Nishiyama Nobuhiro 西山伸宏

… Alternative Names

NISHIYAMA Nobuhiro 西山伸宏

西山信宏ニシヤマノブヒロ

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Researcher Number	10372385
Other IDs
External Links
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 教授 2025: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 主幹研究員
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京工業大学, 科学技術創成研究院, 教授 2017: 東京工業大学, 科学技術創成研究院化学生命科学研究所, 教授 2016 – 2017: 東京工業大学, 化学生命科学研究所, 教授 2012 – 2015: 東京工業大学, 資源化学研究所, 教授 2011 – 2012: 東京大学, 医学(系)研究科(研究院), 准教授 … More 2010 – 2011: 東京大学, 医学系研究院, 准教授 2009 – 2011: The University of Tokyo, 大学院・医学系研究科, 准教授 2009: 東京大学, 医学研究科, 准教授 2008: 東京大学, 工学系研究科, 講師 2007 – 2008: The University of Tokyo, Graduate School of Medicine, Associate Professor 2007: 東京大学, 大学院・医学系研究科 2006: 東京大学, 医学系研究院, 講師 2006: 東京大学, 医学部附属病院, 講師 2006: 東京大学, 大学院医学系研究科, 講師 2006: 東京大学, 大学院工学系研究科, 講師 2005 – 2006: 東京大学, 大学院医学系研究科, 助手 2005 – 2006: 東京大学, 大学院工学系研究科, 助手 2005: The University of Tokyo, Faculty of Medicine, Research Associate, 医学部附属病院, 助手 2004 – 2005: 東京大学, 大学院・医学系研究科, 助手 2004: 東京大学, 大学院・工学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Biomedical engineering/Biomaterial science and engineering / Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / Biomedical engineering/Biomaterial science and engineering / General surgery Except Principal Investigator Cerebral neurosurgery / Digestive surgery / Biomedical engineering/Biological material science … More / Broad Section D / Medical systems / Basic Section 90130:Medical systems-related / Chemistry / Science and Engineering / Nuclear engineering / Plastic surgery / General surgery / Polymer chemistry / Ophthalmology / Surgical dentistry / Biological Sciences Less
Keywords	Principal Investigator 高分子ミセル / イメージング / DDS / がん / ドラッグデリバリーシステム / 光線力学治療 / ドラッグデリバリー / 遺伝子治療 / ナノメディシン / 機能性ポリマー … More / 診断 / MRI / siRNA / セラノスティック / ナノ粒子 / フォトサーマル治療 / 能動的ターゲティング / リガンド分子 / SPECT / 酸化鉄微粒子 / ガドリニウム / バイオ医薬品 / タンパク質デリバリー / コア設計 / スマートシェル / 生理活性タンパク質 / ボロン酸 / タンニン酸 / がん標的化 / 生体適合性ポリマー / 薬物送達システム / 環境応答性高分子 / 微小環境 / pH応答性 / 温度応答性ポリマー / 治療抵抗生がん / 治療抵抗性がん / ターゲティング / アミノ酸トランスポーター / 合成高分子 / ターティング / がん代謝 / がん細胞 / 微小転移 / 低酸素領域 / ポリ(L-リジン) (PLL) / 腎疾患 / ポリ(L-リジン)(PLL) / ポリエチレングリコール(PEG) / ブロック共重合体 / 血管再生 / 虚血性疾患 / がん化学療法 / ナノキャリア / 光エネルギー / 生体内バリア / がん治療 / 光応答型DDS / デンドリマー / 光線力学療法 / ナノテクノロジー / 遺伝子デリバリー … More Except Principal Investigator 癌 / 高分子ミセル / ドラッグデリバリー / RGD / Reverse transfection / 生体材料 / ナノ材料 / ドラッグ・デリバリー / 悪性脳腫瘍 / 化学療法 / siRNA / 核酸 / 脳神経疾患 / がん治療 / 遺伝子治療 / X-band / ポリエチレングリコール / DDS / ブロック共重合体 / biomedical material / nano material / Drug Delivery / Central Nervous System / Cancer / ナノミセル / ドラッグ・デリバリー・システム / Polymer nano-micellsb / Artery wall binding peptide / RGDペプチド / bFGF / がん / 光線力学療法 / ドラッグデリバリーシステム / 脳腫瘍学 / ナノバイオ / トランスレーショナルリサーチ / シグナル伝達 / 移植・再生医療 / がん標的治療 / ナノテクノロジー / がん化学療法 / ミトコンドリア / 腫瘍血管 / ナノ医療 / mRNA / スマートポリマー / LNP / 光温熱 / 低侵襲治療システム / 低侵襲医療 / 光温熱治療 / グルコーストランスポ-ター / 脳―血液関門 / 脳一血液関門 / グルコーストランスポーター / アルツハイマー病 / 脳-血液関門 / 抗体医薬 / プラスミドDNA / メッセンジャーRNA / アンチセンス核酸 / 血液脳関門（BBB） / 薬物送達システム / ポリアミノ酸 / 創薬 / 生体分子 / ゲノム / Dual-energy X-ray CT / Inverse Compton scattering X-ray source / Electron linac / 生物物理 / 廃棄物処理 / 加速器 / 放射線,X線,粒子線 / 2色X線CT / コンプトン散乱X線源 / 電子線形加速器 / nanotechnology / cancer targeted therapy / environment sensitivity / chemotherapeutic agents / cancer chemotherapy / polymeric micelles / drug delivery / 放出制御 / アドリアマイシン / 細胞内環境応答性 / 抗がん剤 / pH応答性 / 制がん剤 / 環境応答性 / 制ガン剤 / Vascular tissue / Gene delivery / Bone regeneration / collagen gel / Reverse transfect / 血管組織 / 遺伝子導入 / 再生骨 / コラーゲンゲル / 高分子ナノミセル構造体 / Therapeutic angiogenesis / Rabbit carotid artery / Intimal Hyperplasia / Acidic gelatin hydrogel / 高分子ミセル型ナノ・パーティクル / 血管新生療法 / 塩基性線維芽細胞増殖因子 / TRAF6 / 治療的血管新生 / 高分子ミセル型ナノパーティクル / コーティング / 高分子ミセル型ナノパーティク / 治療的血管新生療法 / ウサギ頚動脈 / 内膜肥厚 / 高分子ミセル型ナノパーテ / 酸性ゼラチンハイドロゲル / 脳神経腫瘍 / 脳腫瘍 / ナノメディスン / 超分子 / 生体イメージング / 標的化診断・治療 / ナノメディシン / MRI / リポソーム / 中空ナノ粒子 / Rac-1 / ROS / TNF-α遺伝子 / TNF-α / miRNA / GM-CSF / CD40L / YB-1 / TNF一α / トランスレーショナル・リサーチ / 発生・分化 / マイクロアレイ / 機能ポ性リマー / 機能性ポリマー / ナノ送達システム / 骨分化シグナル / 三次元造形法 / 骨再生インプラント / Colla1GFP / インクジェットプリンター / 化合物デリバリーシステム / 化合物スクリーニング / 骨再生療法 / 再生医学 / 人工骨 / 骨再生 / 再生医療 / ナノキャリア Less

Activated mRNA delivery system based on core-shell structured LNP with smart polymers
- Principal Investigator
  
  原島秀吉
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section D
- Research Institution
  Hokkaido University
Development of polymeric micelles based on innovative core-shell design for various therapeutic modalitiesPrincipal Investigator
- Principal Investigator
  
  西山伸宏
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Institute of Science Tokyo
A New Photodynamic Therapy System for Deep Organ Cancer Using an Implantable Light-Emitting Device
- Principal Investigator
  
  YUJI MORIMOTO
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  National Defense Medical College
Development of smart polymeric micelles based on novel shell and core designsPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Nobuhiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo Institute of Technology
Highly efficient cancer treatment system combined with a drug-delivery photoabsorbent agent and a tempreature-controled laser system
- Principal Investigator
  
  Morimoto Yuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  National Defense Medical College
Design of functional polymers responsive to tumor microenvironment and their applications for diagnosis and therapyPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Nobuhiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo Institute of Technology
Development of innovative nucleic acid medicine for gastroenterological cancer
- Principal Investigator
  
  KONNO Masamitsu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
深部がんのイメージングおよび標的治療を可能にする高分子ナノデバイスの創製Principal Investigator
- Principal Investigator
  
  西山伸宏
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Institute of Technology
診断分子と治療分子を搭載したセラノスティック型ナノＤＤＳの創製Principal Investigator
- Principal Investigator
  
  西山伸宏
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Institute of Technology
Design of functional ligand molecules focused on specific metabolism of cancer cells and their applications for diagnosis and therapyPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Nobuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo Institute of Technology
New construction of in vivo reprogramming technology by modified microRNA
- Principal Investigator
  
  ISHII Hideshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
New construction of innovative drug discovery foundation technology for refractory gastrointestinal cancer targeting cancer metabolomics
- Principal Investigator
  
  ISHII Hideshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Development of smart MRI contrast agents based on polymeric micelles to detect tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Nobuhiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo Institute of Technology
Development of Polymeric Micelles for Brain-Targeted Delivery of Nucleic Acid Drugs to Treat Intractable Neurological Diseases
- Principal Investigator
  
  KATAOKA Kazunori
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  The University of Tokyo
固形がんの特異的イメージングのためのＭＲＩ造影剤搭載ナノデバイスの研究開発Principal Investigator
- Principal Investigator
  
  西山伸宏
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
Development of efficient drug and gene delivery system for malignant brain tumors using polymeric nanomicelles.
- Principal Investigator
  
  INO Yasushi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokyo
Theranostic system for cancer by the combination of supramolecular nanocarriers with optical technology
- Principal Investigator
  
  MORIMOTO YUJI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  National Defense Medical College
  防衛医科大学校
Development of systemically injectable siRNA delivery systems by fine-tuning of block copolymersPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Nobuhiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Institute of Technology
  The University of Tokyo
Multidiciplinary TNF・a based gene therapy using polyplex micelle
- Principal Investigator
  
  NAKA Nokenjl
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Development of selective and efficient drug delivery system for malignant brain tumors using polymeric nanomicelles.
- Principal Investigator
  
  INO Yasushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokyo
生体内環境耐性と応答性を兼備したリピド被覆型高分子ミセルドラッグ
- Principal Investigator
  
  片岡一則
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Polymer chemistry
- Research Institution
  The University of Tokyo
Development of Novel Therapeutic Angiogenesis Method by Combination of Nanotechnology and siRNA Targeting PHD2Principal Investigator
- Principal Investigator
  
  NISHIYAMA Nobuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Development of multifunctional polymeric micelles for systemic siRNA delivery
- Principal Investigator
  
  KATAOKA Kazunori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
Novel approach for management of age-related macular degeneration using nanotechnology
- Principal Investigator
  
  TAMAKI Yasuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  The University of Tokyo
Strategic development of a novel implant system to achieve bone regeneration without cell transplantation
- Principal Investigator
  
  TAKATO Tsuyoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Innovative nano-therapy based on nanocarriers equipped with the ability to circumvent biological barriersPrincipal Investigator
- Principal Investigator
  
  NISHIYAMA Nobuhirp
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
Novel Approach for Brain Tumor Treatment using Nano-micelle Drug Delivery System
- Principal Investigator
  
  INO Yasushi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokyo
Polymeric micelle nanocarrier for drug and gene delivery
- Principal Investigator
  
  KATAOKA Kazunori
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Development of functional polymeirc micelles responding to intracellular microenvironments for cancer chemotherapy
- Principal Investigator
  
  KATAOKA Kazunori
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
Development of application of compact tunable monochromatic X-ray source
- Principal Investigator
  
  UESAKA Mitsuru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nuclear engineering
- Research Institution
  THE UNIVERSITY OF TOKYO
部位選択的な遺伝子治療のための光を利用した新規ナノ医療システムの創製Principal Investigator
- Principal Investigator
  
  西山伸宏
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
Novel tissue regeneration using polymer nano-micelle gene delivery system
- Principal Investigator
  
  TAKATO Tsuyoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plastic surgery
- Research Institution
  The University of Tokyo
Nano-micelle Drug Delivery System for the Treatment of Brain Tumors
- Principal Investigator
  
  INO Yasushi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokyo
New support system of vascular surgery using novel bio-materials
- Principal Investigator
  
  KOYAMA Hiroyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo

[Book] ナノメディシン-副作用のない理想的な医薬品の実現に向けて2015
- Author(s)
  西山伸宏
- Publisher
  現代化学東京化学同人
- Data Source
  KAKENHI-PROJECT-25670010
[Book] ナノメディシン-副作用のない理想的な医薬品の実現に向けて2015
- Author(s)
  西山伸宏
- Publisher
  現代化学　東京化学同人
- Data Source
  KAKENHI-PROJECT-23390009
[Book] ナノメディシン-副作用のない理想的な医薬品の実現に向けて2015
- Author(s)
  西山伸宏
- Total Pages
  76
- Publisher
  現代化学東京化学同人
- Data Source
  KAKENHI-PROJECT-13F03042
[Book] 高分子ナノテクノロジーを利用したナノメディシンの開発2014
- Author(s)
  西山伸宏
- Publisher
  最新医学最新医学社
- Data Source
  KAKENHI-PROJECT-23390009
[Book] ナノメディシンによる革新的医薬品の実現に向けて2014
- Author(s)
  西山伸宏
- Total Pages
  104
- Publisher
  BIO Clinica 北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-13F03042
[Book] 標的指向性DDS開発の新展開メディカルサイエンスダイジェスト(Vol. 40 No. 2)「DDS技術の進歩と医療応用」2014
- Author(s)
  西山伸宏
- Total Pages
  106
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-13F03042
[Book] 標的指向性DDS開発の新展開メディカルサイエンスダイジェスト(Vol.40 No.2)「DDS技術の進歩と医療応用」2014
- Author(s)
  西山　伸宏
- Total Pages
  106
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-25670010
[Book] ナノメディシンによる革新的医薬品の実現に向けて2014
- Author(s)
  西山伸宏
- Publisher
  BIO Clinica 北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-25670010
[Book] 高分子ナノパーティクルを用いたDDSの展開2014
- Author(s)
  西山伸宏
- Publisher
  医薬ジャーナル医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-25670010
[Book] 高分子ナノパーティクルを用いたDDSの展開2014
- Author(s)
  西山伸宏
- Total Pages
  165
- Publisher
  医薬ジャーナル医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-13F03042
[Book] 高分子ナノテクノロジーを利用したナノメディシンの開発2014
- Author(s)
  西山伸宏
- Publisher
  最新医学最新医学社
- Data Source
  KAKENHI-PROJECT-25670010
[Book] 高分子ナノパーティクルを用いたDDSの展開2014
- Author(s)
  西山伸宏
- Publisher
  医薬ジャーナル医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-23390009
[Book] ナノメディシンによる革新的医薬品の実現に向けて2014
- Author(s)
  西山伸宏
- Publisher
  BIO Clinica 北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-23390009
[Book] Nonviral Vectors for Gene Therapy : Lipid-and Polymer-based Gene Transfer(Bioresponsive polymer-based nucleic acid carriers)2014
- Author(s)
  H. Takemoto, K. Miyata, N. Nishiyama, K. Kataoka
- Total Pages
  409
- Publisher
  Eds., L. Huang, D. Liu, E. Wagner, Academic Press(Massachusetts, USA)
- Description
  【発行確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Book] 標的指向性DDS開発の新展開メディカルサイエンスダイジェスト(Vol.40 No.2)「DDS技術の進歩と医療応用」2014
- Author(s)
  西山　伸宏
- Total Pages
  106
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-23390009
[Book] ナノテクノロジーの癌医療への応用高分子ミセル型抗癌剤の開発、癌と化学療法36(3)2009
- Author(s)
  西山伸宏、片岡一則
- Data Source
  KAKENHI-PROJECT-17016017
[Book] 細胞工学2008
- Author(s)
  西山伸宏、片岡一則
- Publisher
  人工ウイルスの実現に向けた高分子ミセル型ベクターの設計
- Data Source
  KAKENHI-PROJECT-17016017
[Book] II章5. ナノテクノロジーを利用した DDS 癌の分子標的治療(編集鶴尾隆)2008
- Author(s)
  西山伸宏, 片岡一則
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-19680026
[Book] 第4章機能性DDSキャリアの応用・実用化研究 9. 光応答型DDS機能性DDSキャリア製剤設計(編集岡田弘晃)2008
- Author(s)
  西山伸宏, 片岡一則
- Publisher
  CMC出版
- Data Source
  KAKENHI-PROJECT-19680026
[Book] 細胞工学2008
- Author(s)
  西山伸宏、片岡一則
- Publisher
  人工ウイルスの実現に向けた高分子ミセル型ベクターの設計
- Data Source
  KAKENHI-PROJECT-19680026
[Book] 呼吸と循環2007
- Author(s)
  西山伸宏、鄭雄一、片岡一則
- Publisher
  循環器疾患の治療のためのナノDDS
- Data Source
  KAKENHI-PROJECT-19680026
[Book] ゲノム医学2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  分子標的治療薬とDDSの融合とのその可能性
- Data Source
  KAKENHI-PROJECT-19680026
[Book] Mebio Oncology, 松村保広編、メジカルレビュー社2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  高分子ミセルを利用したがん標的治療
- Data Source
  KAKENHI-PROJECT-19680026
[Book] 血管医学2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  ドラッグデリバリーシステム(DDS)と血管
- Data Source
  KAKENHI-PROJECT-19680026
[Book] ゲノム医学2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  分子標的治療薬とDDSの融合とのその可能性
- Data Source
  KAKENHI-PROJECT-17016017
[Book] レーザー研究2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  デンドリマー光増感剤を利用した部位選択的遺伝子導入
- Data Source
  KAKENHI-PROJECT-17016017
[Book] 呼吸と循環2007
- Author(s)
  西山伸宏、鄭雄一、片岡一則
- Publisher
  循環器疾患の治療のためのナノDDS
- Data Source
  KAKENHI-PROJECT-17016017
[Book] 第II部第1章ナノDDS 医療ナノテクノロジー-最先端医学とナノテクの融合-2007
- Author(s)
  西山伸宏
- Publisher
  杏林図書
- Data Source
  KAKENHI-PROJECT-19680026
[Book] Mebio Oncology, 松村保広編、メジカルレビュー社2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  高分子ミセルを利用したがん標的治療
- Data Source
  KAKENHI-PROJECT-17016017
[Book] 高分子2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  先端医療のためのインテリジェント型高分子ミセルの設計
- Data Source
  KAKENHI-PROJECT-19680026
[Book] 高分子2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  先端医療のためのインテリジェント型高分子ミセルの設計
- Data Source
  KAKENHI-PROJECT-17016017
[Book] レーザー研究2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  デンドリマー光増感剤を利用した部位選択的遺伝子導入
- Data Source
  KAKENHI-PROJECT-19680026
[Book] 血管医学2007
- Author(s)
  西山伸宏、片岡一則
- Publisher
  ドラッグデリバリーシステム(DDS)と血管
- Data Source
  KAKENHI-PROJECT-17016017
[Book] 医学のためのナノ工学2006
- Author(s)
  西山伸宏, 片岡一則
- Total Pages
  6
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-17016017
[Book] 医学のためのナノ工学2006
- Author(s)
  西山伸宏, 片岡一則
- Total Pages
  6
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-16680020
[Book] 体内における部位選択的遺伝子導入を目指した光応答性人工ベクターの開発2006
- Author(s)
  西山伸宏他1名
- Publisher
  バイオテクノロジージャーナル(羊土社)
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Fine tuning of the net charge alternation of polyzwitterion surfaced lipid nanoparticles to enhance cellular uptake and membrane fusion potential2024
- Author(s)
  Homma Keitaro、Miura Yutaka、Kobayashi Motoaki、Chintrakulchai Wanphiwat、Toyoda Masahiro、Ogi Koichi、Michinishi Junya、Ohtake Tomoyuki、Honda Yuto、Nomoto Takahiro、Takemoto Hiroyasu、Nishiyama Nobuhiro
- Journal Title
  
  Science and Technology of Advanced Materials
  
  Volume: 25 Issue: 1 Pages: 2338785-2338785
- DOI
  10.1080/14686996.2024.2338785
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19223, KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-22H00581
[Journal Article] Long noncoding RNA TUG1 promotes cisplatin resistance in ovarian cancer via upregulation of DNA polymerase eta2024
- Author(s)
  Sonobe Ryosuke、Yang Peng、Suzuki Miho M.、Shinjo Keiko、Iijima Kenta、Nishiyama Nobuhiro、Miyata Kanjiro、Kataoka Kazunori、Kajiyama Hiroaki、Kondo Yutaka
- Journal Title
  
  Cancer Science
  
  Volume: 00 Issue: 6 Pages: 1-14
- DOI
  10.1111/cas.16150
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06634, KAKENHI-PROJECT-22H00581
[Journal Article] Polymeric ligands comprising sulfur-containing amino acids for targeting tumor-associated amino acid transporters2023
- Author(s)
  H. Guo, W. Xu, T. Nomoto*, K. Kanamori, Y.M. Voon, Y. Honda, N. Yamada, H. Takemoto, M. Matsui, N. Nishiyama*
- Journal Title
  
  Biomaterials
  
  Volume: 掲載決定 Pages: 121987-121987
- DOI
  10.1016/j.biomaterials.2022.121987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00581, KAKENHI-PROJECT-23K24177
[Journal Article] pH-responsive polyzwitterion covered nanocarriers for DNA delivery2023
- Author(s)
  X. Shen, A. Dirisala, M. Toyoda, Y. Xiao, H. Guo, Y. Honda, T. Nomoto, H. Takemoto, Y. Miura, N. Nishiyama
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 360 Pages: 928-939
- DOI
  10.1016/j.jconrel.2023.07.038
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18322, KAKENHI-PROJECT-23K19223, KAKENHI-PROJECT-23K11841, KAKENHI-PROJECT-21K18062, KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-22H00581, KAKENHI-PROJECT-23K24177
[Journal Article] Polymeric iron chelators for enhancing 5-aminolevulinic acid-induced photodynamic therapy2023
- Author(s)
  T. Nomoto*, K. Komoto, T. Nagano, T. Ishii, H. Guo, Y. Honda, S. Ogura, M. Ishizuka, N. Nishiyama*
- Journal Title
  
  Cancer Sci.
  
  Volume: 114 Issue: 3 Pages: 1086-1094
- DOI
  10.1111/cas.15637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00581, KAKENHI-PROJECT-23K24177
[Journal Article] Self-Folding Macromolecular Drug Carrier for Cancer Imaging and Therapy2023
- Author(s)
  S. Gao, Y. Miura, A. Sumiyoshi, S. Ohno, K. Ogata, T. Nomoto, M. Matsui, Y. Honda, M. Suzuki, M. Iiyama, K. Osada, I. Aoki, N. Nishiyama
- Journal Title
  
  Advanced Science
  
  Volume: 11 Issue: 7 Pages: 2304171-2304171
- DOI
  10.1002/advs.202304171
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18322, KAKENHI-PROJECT-21K19014, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-22H00581, KAKENHI-PROJECT-23K21857, KAKENHI-PROJECT-23K24177
[Journal Article] Umbilical cord?derived mesenchymal stem cell sheets transplanted subcutaneously enhance cell retention and survival more than dissociated stem cell injections2023
- Author(s)
  Mitsuyoshi Nakao, Makoto Matsui, Kyungsook Kim, Nobuhiro Nishiyama, David W. Grainger, Teruo Okano, Hideko Kanazawa, Kenichi Nagase
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 14 Issue: 1 Pages: 352-352
- DOI
  10.1186/s13287-023-03593-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19899, KAKENHI-PROJECT-21KK0199, KAKENHI-PUBLICLY-22H04560, KAKENHI-PROJECT-22H00581
[Journal Article] Site-activatable targeting of macromolecular alendronate for accelerated fracture healing2023
- Author(s)
  M. Matsui, Y. Kaihara, Y. Honda, N. Nishiyama, Y. Miura
- Journal Title
  
  Science and Technology of Advanced Materials
  
  Volume: 24 Issue: 1 Pages: 2286218-2286218
- DOI
  10.1080/14686996.2023.2286218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18322, KAKENHI-PROJECT-23H05451, KAKENHI-PROJECT-22H00581
[Journal Article] Thermo-Responsive Polymer-siRNA Conjugates Enabling Artificial Control of Gene Silencing around Body Temperature2023
- Author(s)
  Y. Honda, S. Onodera, H. Takemoto, N. F. C. Harun, T. Nomoto, M. Matsui, K. Tomoda, Y. Sun, Y. Miura, N. Nishiyama
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 40 Issue: 1 Pages: 157-165
- DOI
  10.1007/s11095-022-03414-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18322, KAKENHI-PROJECT-22H00581, KAKENHI-PROJECT-23K24177
[Journal Article] Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration2022
- Author(s)
  3.A. Awaad, H. Takemoto, M. Iizuka, K. Ogi, Y. Mochida, AH Ranneh, M. Toyoda, M. Matsui, T. Nomoto, Y. Honda, K. Hayashi, K. Tomoda, T. Ohtake, Y. Miura, N. Nishiyama
- Journal Title
  
  J. Control Release.
  
  Volume: 1;346 Pages: 392-404
- DOI
  10.1016/j.jconrel.2022.04.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18322, KAKENHI-PROJECT-22H00581
[Journal Article] Quantitative analysis of acoustic pressure for sonophoresis and its effect on transdermal penetration2022
- Author(s)
  Y. Kurashina*, R. Asano, M. Matsui, T. Nomoto, K. Ando, K. Nakamura, N. Nishiyama, Y. Kitamoto
- Journal Title
  
  Ultrasound Med Biol.
  
  Volume: 48 Issue: 5 Pages: 933-944
- DOI
  10.1016/j.ultrasmedbio.2022.01.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00581, KAKENHI-PROJECT-21H01272
[Journal Article] Cancerous pH‐responsive polycarboxybetaine‐coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model in mice2022
- Author(s)
  Y. Sung, H. Guo, A. Ghasemizadeh, X. Shen, W. Chintrakulchai, M. Kobayashi, M. Toyoda, K. Ogi, J. Michinishi, T. Ohtake, M. Matsui, Y. Honda, T. Nomoto, H. Takemoto, Y. Miura, N. Nishiyama
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 12 Pages: 4339-4349
- DOI
  10.1111/cas.15554
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18322, KAKENHI-PROJECT-21K20513, KAKENHI-PROJECT-22H00581, KAKENHI-PROJECT-23K24177
[Journal Article] Fructose-functionalized polymers to enhance therapeutic potential of p-boronophenylalanine for neutron capture therapy2021
- Author(s)
  Nomoto Takahiro、Yao Ying、Inoue Yukiya、Suzuki Minoru、Kanamori Kaito、Takemoto Hiroyasu、Matsui Makoto、Tomoda Keishiro、Nishiyama Nobuhiro
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 332 Pages: 184-193
- DOI
  10.1016/j.jconrel.2021.02.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-18H04163
[Journal Article] Systemically applicable glutamine-functionalized polymer exerting multivalent interaction with tumors overexpressing ASCT22021
- Author(s)
  Y. Honda, T. Nomoto, H. Takemoto, M. Matsui, K. Taniwaki, H. Guo, Y. Miura, N. Nishiyama
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 4(10) Issue: 10 Pages: 7402-7407
- DOI
  10.1021/acsabm.1c00771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18322, KAKENHI-PROJECT-18H04163
[Journal Article] Nanoprobe-based magnetic resonance imaging of hypoxia predicts responses to radiotherapy, immunotherapy, and sensitizing treatments in pancreatic tumors2021
- Author(s)
  J. Liu, H. Cabral, T. Aoki, N. Nishiyama, Y. Huang, K. Kataoka, P. Mi
- Journal Title
  
  ACS Nano
  
  Volume: 15 Issue: 8 Pages: 13526-13538
- DOI
  10.1021/acsnano.1c04263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04163
[Journal Article] Synthesis of near-infrared absorbing triangular Au nanoplates using biomineralisation peptides2021
- Author(s)
  M. Tanaka, M. Hayashi, L. Roach, Y. Kiriki, T. Kadonosono, T. Nomoto, N. Nishiyama, J. Choi, K. Critchley, S.D. Evans, M. Okochi
- Journal Title
  
  ACTA Biomaterialia
  
  Volume: 131 Pages: 519-531
- DOI
  10.1016/j.actbio.2021.06.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04163
[Journal Article] Polymeric iron chelators enhancing pro-oxidant antitumor efficacy of vitamin C by inhibiting the extracellular fenton reaction2021
- Author(s)
  H. Guo, T. Nomoto, S. E. Muttaqien, X. Sun, K. Komoto, M. Matsui, Y. Miura, N. Nishiyama
- Journal Title
  
  Mol Pharm.
  
  Volume: 18(12) Issue: 12 Pages: 4475-4485
- DOI
  10.1021/acs.molpharmaceut.1c00673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18322, KAKENHI-PROJECT-18H04163
[Journal Article] Sequentially self-assembled nanoreactor comprising tannic acid and phenylboronic acid-conjugated polymers inducing tumor-selective enzymatic activity2021
- Author(s)
  Y. Honda, T. Nomoto, M. Matsui, H. Takemoto, Y. Miura, N. Nishiyama
- Journal Title
  
  ACS Appl. Mater. Inter.
  
  Volume: 13(46) Issue: 46 Pages: 54850-54859
- DOI
  10.1021/acsami.1c20188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18322, KAKENHI-PROJECT-18H04163
[Journal Article] Differential Effect of Azetidine Substitution in Firefly Luciferin Analogues2021
- Author(s)
  Ikeda Yuma、Orioka Mariko、Nomoto Takahiro、Hiruta Yuki、Nishiyama Nobuhiro、Citterio Daniel
- Journal Title
  
  ChemBioChem
  
  Volume: 22 Issue: 21 Pages: 3067-3074
- DOI
  10.1002/cbic.202100310
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H00437, KAKENHI-PROJECT-18H04163
[Journal Article] Potential urinary monitoring of the enhanced permeability and retention effect using MMP-2-responsive poly(ethylene glycol) derivatives2020
- Author(s)
  X. Sun, T. Nomoto, H. Takemoto, M. Matsui, H. Guo, Y. Sun, Y. Miura, N. Nishiyama*
- Journal Title
  
  J. Control. Release
  
  Volume: 329 Pages: 513-523
- DOI
  10.1016/j.jconrel.2020.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-20K20196
[Journal Article] Photodynamic therapy using LCST polymers exerting pH-responsive isothermal phase transition2020
- Author(s)
  S. Muttaqien, T. Nomoto*, X. Dou, H. Takemoto, M. Matsui, N. Nishiyama*
- Journal Title
  
  J. Control. Release
  
  Volume: 328 Pages: 608-616
- DOI
  10.1016/j.jconrel.2020.09.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-20K20196
[Journal Article] Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects2020
- Author(s)
  Takemoto Hiroyasu、Inaba Takanori、Nomoto Takahiro、Matsui Makoto、Liu Xiaomeng、Toyoda Masahiro、Honda Yuto、Taniwaki Kaori、Yamada Naoki、Kim Junhyun、Tomoda Keishiro、Nishiyama Nobuhiro
- Journal Title
  
  Biomaterials
  
  Volume: 235 Pages: 119804-119804
- DOI
  10.1016/j.biomaterials.2020.119804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-19K20693, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-18J01989, KAKENHI-PROJECT-18K09020
[Journal Article] Iron chelation cancer therapy using hydrophilic block copolymers conjugated with deferoxamine2020
- Author(s)
  K. Komoto, T. Nomoto*, S. Muttaqien, H. Takemoto, M. Matsui, Y. Miura, N. Nishiyama*
- Journal Title
  
  Cancer Sci.
  
  Volume: 112 Issue: 1 Pages: 410-421
- DOI
  10.1111/cas.14607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-20K20196
[Journal Article] Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery2020
- Author(s)
  Honda Yuto、Nomoto Takahiro、Matsui Makoto、Takemoto Hiroyasu、Kaihara Yuka、Miura Yutaka、Nishiyama Nobuhiro
- Journal Title
  
  Biomacromolecules
  
  Volume: 21 Issue: 9 Pages: 3826-3835
- DOI
  10.1021/acs.biomac.0c00903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-18H04163
[Journal Article] Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism2020
- Author(s)
  Nomoto Takahiro、Inoue Yukiya、Yao Ying、Suzuki Minoru、Kanamori Kaito、Takemoto Hiroyasu、Matsui Makoto、Tomoda Keishiro、Nishiyama Nobuhiro
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 4
- DOI
  10.1126/sciadv.aaz1722
- NAID
  120006779811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-17H04743
[Journal Article] In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers2019
- Author(s)
  Watanabe Sumiyo、Hayashi Kotaro、Toh Kazuko、Kim Hyun Jin、Liu Xueying、Chaya Hiroyuki、Fukushima Shigeto、Katsushima Keisuke、Kondo Yutaka、Uchida Satoshi、Ogura Satomi、Nomoto Takahiro、et al.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1894-1894
- DOI
  10.1038/s41467-019-09856-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-19K12799, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-18H02797, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-17H02098
[Journal Article] Pyruvate Responsiveness Based on α-Oxohydrazone Formation for Intracellular siRNA Release from Polyion Complex-Based Carriers2019
- Author(s)
  Takemoto Hiroyasu、Wang Chih-Ling、Nomoto Takahiro、Matsui Makoto、Tomoda Keishiro、Nishiyama Nobuhiro
- Journal Title
  
  Biomacromolecules
  
  Volume: 20 Issue: 6 Pages: 2305-2314
- DOI
  10.1021/acs.biomac.9b00261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-17H04743
[Journal Article] Sonodynamic therapy with anticancer micelles and high-intensity focused ultrasound in treatment of canine cancer2019
- Author(s)
  Y. Hirose, M. Maeda, Y. Konishi, J. Okamoto, S. Ikuta, Y. Okamoto, H. Ishii, S. Yoshizawa, S. Umemura, T. Ueyama, S. Tamano, A. Sofuni, K. Takemae, K. Masamune, H. Iseki, N. Nishiyama, K. Kataoka, Y. Muragaki
- Journal Title
  
  Front. Pharmacol.
  
  Volume: 10 Pages: 545-545
- DOI
  10.3389/fphar.2019.00545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-16H03160
[Journal Article] Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers2018
- Author(s)
  Dou Xuebo、Nomoto Takahiro、Takemoto Hiroyasu、Matsui Makoto、Tomoda Keishiro、Nishiyama Nobuhiro
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8126-8126
- DOI
  10.1038/s41598-018-26593-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407
[Journal Article] Poly(N-isopropylacrylamide)-Based Polymer-Inducing Isothermal Hydrophilic-to-Hydrophobic Phase Transition via Detachment of Hydrophilic Acid-Labile Moiety2018
- Author(s)
  Muttaqien Sjaikhurrizal El、Nomoto Takahiro、Takemoto Hiroyasu、Matsui Makoto、Tomoda Keishiro、Nishiyama Nobuhiro
- Journal Title
  
  Biomacromolecules
  
  Volume: 20 Issue: 4 Pages: 1493-1504
- DOI
  10.1021/acs.biomac.8b01465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-18H04163
[Journal Article] Poly(ethylene glycol)ーpoly(lysine) block copolymerーubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells2018
- Author(s)
  Toshiyama, R., Konno, M., Eguchi, H., Takemoto, H., Noda, T., Asai, A., Koseki, J., Haraguchi, N., Ueda, Y. Matsushita, K., Asukai, K., Ohashi, T., Iwagami, Y., Yamada, D., Sakai, D., Asaoka, T., Kudo, T., Kawamoto, K., Gotoh, K., Kobayashi, S., Satoh, T., Doki, Y., Nishiyama, N., Mori, M., Ishii, H.
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 2 Pages: 244-260
- DOI
  10.1038/s41388-018-0406-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16355, KAKENHI-PROJECT-18K16356, KAKENHI-PROJECT-18KK0251, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-17K19698, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06279
[Journal Article] An Ethylenediamine‐based Switch to Render the Polyzwitterion Cationic at Tumorous pH for Effective Tumor Accumulation of Coated Nanomaterials2018
- Author(s)
  Abdul-Hackam Ranneh, Hiroyasu Takemoto, Shunya Sakuma, Aziz Awaad, Takahiro Nomoto, Yuki Mochida, Makoto Matsui, Keishiro Tomoda, Mitsuru Naito, Nobuhiro Nishiyama
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Issue: 18 Pages: 5057-5061
- DOI
  10.1002/anie.201801641
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19481, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-16F16407
[Journal Article] Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release2018
- Author(s)
  Chida Tsukasa、Miura Yutaka、Cabral Horacio、Nomoto Takahiro、Kataoka Kazunori、Nishiyama Nobuhiro
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 292 Pages: 130-140
- DOI
  10.1016/j.jconrel.2018.10.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-16H05422, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407
[Journal Article] Utility of the 2-nitrobenzenesulfonamide group as a chemical linker for enhanced extracellular stability and cytosolic cleavage in siRNA-conjugated polymer systems2017
- Author(s)
  C. H. Huang, H. Takemoto, T. Nomoto, K. Tomoda, M. Matsui, N. Nishiyama
- Journal Title
  
  ChemMedChem
  
  Volume: 12 Issue: 1 Pages: 19-22
- DOI
  10.1002/cmdc.201600488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-15K16331, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104
[Journal Article] Inhibition of PRDM14 expression in pancreatic cancer suppresses cancer stem-like properties and liver metastasis in mice2017
- Author(s)
  C. Moriya, H. Taniguchi, K. Miyata, N. Nishiyama, K. Kataoka, K. Imai
- Journal Title
  
  Carcinogenesis
  
  Volume: 38 Issue: 6 Pages: 638-648
- DOI
  10.1093/carcin/bgx040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297, KAKENHI-PROJECT-17H02098
[Journal Article] cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells2017
- Author(s)
  Miyano Kazuki、Cabral Horacio、Miura Yutaka、Matsumoto Yu、Mochida Yuki、Kinoh Hiroaki、Iwata Caname、Nagano Osamu、Saya Hideyuki、Nishiyama Nobuhiro、Kataoka Kazunori、Yamasoba Tatsuya
- Journal Title
  
  J Control Release
  
  Volume: 261 Pages: 275-286
- DOI
  10.1016/j.jconrel.2017.06.021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16H05422, KAKENHI-PROJECT-17H06641, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104
[Journal Article] Multilayered polyion complexes with dissolvable silica layer covered by controlling densities of cRGD-conjugated PEG chains for cancer-targeted siRNA delivery.2017
- Author(s)
  M. Naito, R. Azuma, H. Takemoto, M. Hori, N. Yoshinaga, S. Osawa, R. Kamegawa, H. -J. Kim, T. Ishii, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  J. Biomater. Sci. Polym.
  
  Volume: 28 Issue: 10-12 Pages: 1109-1123
- DOI
  10.1080/09205063.2017.1301775
- Description
  【掲載確定】 in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-25282141
[Journal Article] Functional polymer-based siRNA delivery carrier that recognizes site-specific biosignals2017
- Author(s)
  Hiroyasu Takemoto, Nobuhiro Nishiyama
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 267 Pages: 90-99
- DOI
  10.1016/j.jconrel.2017.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19481, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104
[Journal Article] Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer2017
- Author(s)
  H. Taniguchi, D. Hoshino, C. Moriya, H. Zembutsu, N. Nishiyama, H. Yamamoto, K. Kataoka, K. Imai
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 29 Pages: 46856-46874
- DOI
  10.18632/oncotarget.16776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104
[Journal Article] cRGD peptide-installed epirubicin-loaded polymeric micelles for effective targeted therapy against brain tumors2017
- Author(s)
  S. Quader, X. Liu, Y. Chen, P. Mi, T. Chida, T. Ishii, Y. Miura, N. Nishiyama, H. Cabral, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 258 Pages: 56-66
- DOI
  10.1016/j.jconrel.2017.04.033
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-16K12904
[Journal Article] Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain2017
- Author(s)
  Anraku Y.、Kuwahara H.、Fukusato Y.、Mizoguchi A.、Ishii T.、Nitta K.、Matsumoto Y.、Toh K.、Miyata K.、Uchida S.、Nishina K.、Osada K.、Itaka K.、Nishiyama N.、Mizusawa H.、Yamasoba T.、Yokota T.、Kataoka K.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 2001-2009
- DOI
  10.1038/s41467-017-00952-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-15H04813, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
[Journal Article] Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors.2017
- Author(s)
  P. Mi, H. Yanagie, N. Dewi, H.-C. Yen, X. Liu, M. Suzuki, Y. Sakurai, K. Ono, H. Takahashi, H. Cabral, K. Kataoka,
- Journal Title
  
  J. Control. Release
  
  Volume: 254 Pages: 1-9
- DOI
  10.1016/j.jconrel.2017.03.036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-25293267, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K12534
[Journal Article] Sonodynamic therapy based on combined use of low dose administration of epirubicin-incorporating drug delivery system and focused ultrasound2017
- Author(s)
  M. Maeda, Y. Muragaki, J. Okamoto, S. Yoshizawa, N. Abe, H. Nakamoto, H. Ishii, K. Kawabata, S. Umemura, N. Nishiyama, K. Kataoka, H. Iseki
- Journal Title
  
  Ultrasound Med. Biol.
  
  Volume: 43 Issue: 10 Pages: 2295-2301
- DOI
  10.1016/j.ultrasmedbio.2017.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H03188, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104
[Journal Article] Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism2017
- Author(s)
  Yamada Naoki、Honda Yuto、Takemoto Hiroyasu、Nomoto Takahiro、Matsui Makoto、Tomoda Keishiro、Konno Masamitsu、Ishii Hideshi、Mori Masaki、Nishiyama Nobuhiro
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 6077-6077
- DOI
  10.1038/s41598-017-06438-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19698, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16J10727, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-16K15615
[Journal Article] Calcium phosphate-based organic-inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy2016
- Author(s)
  T. Nomoto, S. Fukushima, M. Kumagai, K. Miyazaki, A. Inoue, P. Mi, Y. Maeda, K. Toh, Y. Matsumoto, Y. Morimoto, A. Kishimura, N. Nishiyama, K. Kataoka
- Journal Title
  
  Biomater. Sci.
  
  Volume: 印刷中 Issue: 5 Pages: 826-838
- DOI
  10.1039/c6bm00011h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-26882022, KAKENHI-PROJECT-26670738, KAKENHI-PROJECT-26288082, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-26293295
[Journal Article] Artificial Control of Gene Silencing Activity Based on siRNA Conjugation with Polymeric Molecule Having Coil Globule Transition Behavior2016
- Author(s)
  Noor Faizah Che Harun, Hiroyasu Takemoto, Takahiro Nomoto, Keishiro Tomoda, Makoto Matsui, and Nobuhiro Nishiyama
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 27 Issue: 9 Pages: 1961-1964
- DOI
  10.1021/acs.bioconjchem.6b00322
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K16331, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104
[Journal Article] Intracellular Delivery of Charge-Converted Monoclonal Antibodies by Combinatorial Design of Block/Homo Polyion Complex Micelles2016
- Author(s)
  Ahram Kim, Yutaka Miura, Takehiko Ishii, Omer F. Mutaf, Nobuhiro Nishiyama, Horacio Cabral, Kazunori Kataoka
- Journal Title
  
  Biomacromolecules
  
  Volume: 17 Issue: 2 Pages: 446-453
- DOI
  10.1021/acs.biomac.5b01335
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-24689051
[Journal Article] Synthetic polyamines to regulate mRNA translation through the preservative binding of eukaryotic initiation factor 4E to the cap structure.2016
- Author(s)
  H. Uchida, K. Itaka, S. Uchida, T. Ishii, T. Suma, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 138 Issue: 5 Pages: 1478-1481
- DOI
  10.1021/jacs.5b11726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
[Journal Article] Influence of RNA strand rigidity on polyion complex formation with block catiomers.2016
- Author(s)
  K. Hayashi, H. Chaya, S. Fukushima, S. Watanabe, H. Takemoto, K. Osada, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  Macromol. Rapid Commun.
  
  Volume: 37 Issue: 6 Pages: 486-493
- DOI
  10.1002/marc.201500661
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16331, KAKENHI-PROJECT-14J10626, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
[Journal Article] Rapid Cancer Fluorescence Imaging Using A γ-Glutamyltranspeptidase-Specific Probe For Primary Lung Cancer.2016
- Author(s)
  Hino H, Kamiya M, Kitano K, Mizuno K, Tanaka S, Nishiyama N, Kataoka K, Urano Y, Nakajima J
- Journal Title
  
  Translational Oncology.
  
  Volume: 9 Issue: 3 Pages: 203-210
- DOI
  10.1016/j.tranon.2016.03.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05951, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-15K10252, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104
[Journal Article] Nanomedicines eradicating cancer stem-like cells in vivo by pH-triggered intracellular cooperative action of loaded drugs.2016
- Author(s)
  H. Kinoh, Y. Miura, T. Chida, X. Liu, K. Mizuno, S. Fukushima, Y. Morodomi, N. Nishiyama, H. Cabral, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 10 Issue: 6 Pages: 5643-5655
- DOI
  10.1021/acsnano.6b00900
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K12534
[Journal Article] A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy.2016
- Author(s)
  P. Mi, D. Kokuryo, H. Cabral, H. Wu, Y. Terada, T. Saga, I. Aoki, N. Nishiyama, K. Kataoka,
- Journal Title
  
  Nat. Nanotechnol.
  
  Volume: 11 Issue: 8 Pages: 724-730
- DOI
  10.1038/nnano.2016.72
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-24300167, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-26293295, KAKENHI-PROJECT-15K12534
[Journal Article] cRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis2016
- Author(s)
  Jun Makino, Horacio Cabral, Yutaka Miura, Yu Matsumoto, Ming Wang, Hiroaki Kinoh, Yuki Mochida, Nobuhiro Nishiyama, Kazunori Kataoka
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 220 PartB Pages: 783-791
- DOI
  10.1016/j.jconrel.2015.10.017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-26670738, KAKENHI-PROJECT-24689051
[Journal Article] Development of polymeric micelles for targeting intractable cancers2016
- Author(s)
  N. Nishiyama, Y. Matsumura, K. Kataoka
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 7 Pages: 867-874
- DOI
  10.1111/cas.12960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104
[Journal Article] Synthesis of PEGylated poly(amino acid) pentablock copolymers and their self-assembly.2016
- Author(s)
  Iijima, M., Ulkoski, D., Sakuma, S., Matsukuma, D., Nishiyama, N., Otsuka, H. and Scholz, C.
- Journal Title
  
  Polym. Int.
  
  Volume: 65 Issue: 10 Pages: 1132-1141
- DOI
  10.1002/pi.5159
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26288064, KAKENHI-PROJECT-15H04635
[Journal Article] Antibody fragment-conjugated polymeric micelles incorporating platinum drugs for targeted therapy of pancreatic cancer2015
- Author(s)
  J. -Y. Ahn, Y. Miura, N. Yamada, T. Chida, X. Liu, A. Kim, R. Sato, R. Tsumura, Y. Koga, M. Yasunaga, N. Nishiyama, Y. Matsumura, H. Cabral, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 39 Pages: 23-30
- DOI
  10.1016/j.biomaterials.2014.10.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] MicroRNAs induce epigenetic reprogramming and suppress malignant phenotypes of human colon cancer cells.2015
- Author(s)
  Ogawa, H., Wu, X., Kawamoto, K., Nishida, N., Konno, M., Koseki, J., Matsui, H., Noguchi, K., Gotoh, N., Yamamoto, T., Miyata, K., Nishiyama, N., Nagano, H., Yamamoto, H., Obika, S., Kataoka, K., Doki, Y., Mori, M., Ishii, H.
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 5 Pages: 1-23
- DOI
  10.1371/journal.pone.0127119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15474, KAKENHI-PROJECT-15H04294, KAKENHI-PROJECT-15H05664, KAKENHI-PROJECT-26640072, KAKENHI-PROJECT-26670604, KAKENHI-PROJECT-26293303, KAKENHI-PROJECT-15H05791
[Journal Article] MicroRNAs induce epigenetic reprogramming and suppress malignant phenotypes of human colon cancer cells.2015
- Author(s)
  Ogawa, H., Wu, X., Kawamoto, K., Nishida, N., Konno, M., Koseki, J., Matsui, H., Noguchi, K., Gotoh, N., Yamamoto, T., Miyata, K., Nishiyama, N., Nagano, H., Yamamoto, H., Obika, S., Kataoka, K., Doki, Y., Mori, M., Ishii, H.
- Journal Title
  
  PLoS One.
  
  Volume: 10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15496
[Journal Article] Multicompartment Micelles with Adjustable Poly (ethylene glycol) Shell for Efficient In Vivo Photodynamic Therapy2014
- Author(s)
  Synatschke CV, Nomoto T, Cabral H, Förtsch M, Toh K, Matsumoto Y, Miyazaki K, Hanisch A, Schacher FH, Kishimura A, Nishiyama N, Müller AHE, Kataoka K
- Journal Title
  
  ACS nano
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23300174
[Journal Article] Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles2014
- Author(s)
  H. -J. Kim, H. Takemoto, Y. Yi, M. Zheng, Y. Maeda, H. Chaya, K. Hayashi, P. Mi, F. Pittella, R. J. Christie, K. Toh, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 8 Issue: 9 Pages: 8979-8991
- DOI
  10.1021/nn502125h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] Light-induced cytosolic activation of reduction-sensitive camptothecin-loaded polymeric micelles for spatiotemporally controlled in vivo chemotherapy2014
- Author(s)
  H.-C. Yen, H. Cabral, P. Mi, K. Toh, Y. Matsumoto, X. Liu, H. Koori, A. Kim, K. Miyazaki, Y. Miura, N. Nishiyama, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 8 Issue: 11 Pages: 11591-11602
- DOI
  10.1021/nn504836s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172, KAKENHI-PROJECT-26670738
[Journal Article] siRNA delivery from triblock copolymer micelles with spatially-ordered compartmants of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core2014
- Author(s)
  Hyun Jin Kim, Kanjiro Miyata, Takahiro Nomoto, Meng Zheng, Ahram Kim, Xueying Liu, Horacio Cabral, R. James Christie, Nobuhiro Nishiyama, Kazunori Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 15 Pages: 4548-4556
- DOI
  10.1016/j.biomaterials.2014.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors2014
- Author(s)
  Y. Oe, R. J. Christie, M. Naito, S. A. Low, S. Fukushima, K. Toh, Y. Miura, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 27 Pages: 7887-7895
- DOI
  10.1016/j.biomaterials.2014.05.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] Multicompartment micelles with adjustable poly (ethylene glycol) shell for efficient in vivo photodynamic therapy2014
- Author(s)
  C. V. Synatschke, N. Nishiyama, et al.
- Journal Title
  
  ACS Nano
  
  Volume: (in press)(印刷中)(掲載確定) Issue: 2 Pages: 1161-1172
- DOI
  10.1021/nn4028294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172, KAKENHI-PROJECT-26670738
[Journal Article] Polymeric micelles loaded with platinum anticancer drugs target preangiogenic micrometastatic niches associated with inflammation2014
- Author(s)
  H. Wu, H. Cabral, K. Toh, P. Mi, Y.-C. Chen, Y. Matsumoto, N. Yamada, X. Liu, H. Kinoh, Y. Miura, M. R. Kano, H. Nishihara, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 189 Pages: 1-10
- DOI
  10.1016/j.jconrel.2014.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-26670738
[Journal Article] Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer2014
- Author(s)
  Hyun Jin Kim, Takehiko Ishii, Meng Zheng, Sumiyo Watanabe, Kazuko Toh, Yu Matsumoto, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka
- Journal Title
  
  Drug Delivery and Translational Research
  
  Volume: 4 Issue: 1 Pages: 50-60
- DOI
  10.1007/s13346-013-0175-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] Elucidating the molecular mechanism for the intracellular trafficking and fate of block copolymer micelles and their components2014
- Author(s)
  K. -S. Kato, N. Nishiyama, et al.
- Journal Title
  
  Biomaterials
  
  Volume: 35 Issue: 5 Pages: 1347-1358
- DOI
  10.1016/j.biomaterials.2013.11.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25670010
[Journal Article] Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles2014
- Author(s)
  F. Pittella, N. Nishiyama, et al.
- Journal Title
  
  J. Control. Release
  
  Volume: 178 Pages: 18-24
- DOI
  10.1016/j.jconrel.2014.01.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Preconditioning methods influence tumor property in an orthotopic bladder urothelial carcinoma rat model2014
- Author(s)
  Miyazaki K, Morimoto Y, Nishiyama N, Satoh H, Tanaka M, Shinomiya N, Ito K
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 2(1) Pages: 65-70
- Data Source
  KAKENHI-PROJECT-23300174
[Journal Article] Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer2014
- Author(s)
  T. Nomoto, S. Fukushima, M. Kumagai, K. Machitani, Arnida, Y. Matsumoto, M. Oba, K. Miyata, K. Osada, N. Nishiyama, K. Kataoka
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 3545-3545
- DOI
  10.1038/ncomms4545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25670010
[Journal Article] Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection2014
- Author(s)
  H. Uchida, K. Itaka, T. Nomoto, T. ishii, T. Suma, M. Ikegami, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Issue: 35 Pages: 12396-12405
- DOI
  10.1021/ja506194z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006
[Journal Article] Polyion complex vesicles for photo-induced intracellular delivery of amphiphilic photosensitizer2014
- Author(s)
  H. Chen, L. Xiao, Y. Anraku, P. Mi, X. Liu, H. Cabral, A. Inoue, T. Nomoto, A. Kishimura, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 Pages: 157-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009
[Journal Article] Fine-tuning of charge-conversion polymer structure for efficient endosomal escape of siRNA-loaded calcium phosphate hybrid micelles2014
- Author(s)
  Y. Maeda, F. Pittella, T. Nomoto, H. Takemoto, N. Nishiyama, K. Miyata, K. Kataoka
- Journal Title
  
  Macromol. Rapid Commun.
  
  Volume: 35 Issue: 13 Pages: 1211-1215
- DOI
  10.1002/marc.201400049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006
[Journal Article] Hydrothermally synthesized PEGylated calcium phosphate nanoparticles incorporating Gd-DTPA for contrast enhanced MRI diagnosis of solid tumors2014
- Author(s)
  P. Mi, N. Nishiyama, et al.
- Journal Title
  
  J. Control. Release
  
  Volume: 136 Issue: 1 Pages: 157-163
- DOI
  10.1021/ja406992w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23685037, KAKENHI-PROJECT-24700476, KAKENHI-PUBLICLY-25107709, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Hydrothermally synthesized PEGylated calcium phosphate nanoparticles incorporating Gd-DTPA for contrast enhanced MRI diagnosis of solid tumors2014
- Author(s)
  P. Mi, D. Kokuryo, H. Cabral, M. Kumagai, T. Nomoto, I. Aoki, Y. Terada, A. Kishimura, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 174 Pages: 63-71
- DOI
  10.1016/j.jconrel.2013.10.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PUBLICLY-25107709, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Bundled assembly of helical nanostructures in polymeric micelles loaded with platinum drugs enhancing therapeutic efficiency against pancreatic tumor2014
- Author(s)
  Y. Mochida, H. Cabral, Y. Miura, F. Albertini, S. Fukushima, K. Osada, N. Nishiyama, K. Kataoka
- Journal Title
  
  ACS Nano
  
  Volume: 8 Issue: 7 Pages: 6724-6738
- DOI
  10.1021/nn500498t
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Acidic pH-Responsive siRNA Conjugate for Reversible Carrier Stability and Accelerated Endosoraal Escape with Reduced IFNα -Associated Immune Response2013
- Author(s)
  Hiroyasu Takemoto, Kanjiro Miyata, Shota Hattori, Takehiko Ishii, Toraoya Suma, Satoshi Uchida, Nobuhiro Nishiyama and Kazunori Kataoka
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 52 Issue: 24 Pages: 6218-6221
- DOI
  10.1002/anie.201300178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08644, KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23390009
[Journal Article] Phenylboronic acid-installed polymeric micelles for targeting sialylated epitopes in solid tumors.2013
- Author(s)
  S. Deshayes, N. Nishiyama, et al.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 41 Pages: 15501-15507
- DOI
  10.1021/ja406406h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
[Journal Article] Polyion Complex Vesicles for Photoinduced Intracellular Delivery of Amphiphilic Photosensitizer2013
- Author(s)
  Chen H, Xiao L, Anraku Y, Mi P, Liu X, Cabral H, Inoue A, Nomoto T, Kishimura A, Nishiyama N, Kataoka K
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 136(1) Pages: 157-163
- Data Source
  KAKENHI-PROJECT-23300174
[Journal Article] Targeted therapy of spontaneous murine pancreatic tumors by polymeric micelles prolongs survival and prevents peritoneal metastasis2013
- Author(s)
  H. Cabral, N. Nishiyama, et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 110 Issue: 28 Pages: 11397-11402
- DOI
  10.1073/pnas.1301348110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790433, KAKENHI-PROJECT-25670010
[Journal Article] SPIO-PlCsome : Development of a highly sensitive and stealth-capable MRI nano-agent for tumor detection using SPIO-loaded unilamellar polyion complex vesicles (PICsomes)2013
- Author(s)
  D. Kokuryo, N. Nishiyama, et al.
- Journal Title
  
  J. Control. Release
  
  Volume: 169 Issue: 3 Pages: 220-227
- DOI
  10.1016/j.jconrel.2013.03.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23685037, KAKENHI-PROJECT-24700476, KAKENHI-PROJECT-25670010
[Journal Article] Transcription factor YYI contributes to tumor growth by stabilizing hypoxia fact or HIF-lα in a p53-independent manner.2013
- Author(s)
  S. Wu, N. Nishiyama, et al.
- Journal Title
  
  Cancer Res.
  
  Volume: 73 Issue: 6 Pages: 1787-1799
- DOI
  10.1158/0008-5472.can-12-0366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051
[Journal Article] Silica nanogelling of environment-responsive PEGylated polyplexes for enhanced stability and intracellular delivery of siRNA2013
- Author(s)
  N. Gouda, K. Miyata
- Journal Title
  
  Biomaterials
  
  Volume: 34 Issue: 2 Pages: 562-570
- DOI
  10.1016/j.biomaterials.2012.09.077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23685037
[Journal Article] Gd-DTPA-loaded polymer-metal complex micelles with high relaxivity for MR cancer imaging2013
- Author(s)
  P. Mi, H. Cabrala, D. Kokuryo, M. Rafi, Y. Terada, I. Aoki, T. Saga, T. Ishii, N. Nishiyama, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 34 Issue: 2 Pages: 492-500
- DOI
  10.1016/j.biomaterials.2012.09.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23700526, KAKENHI-PROJECT-25670010
[Journal Article] Rational design of smart supramolecular assemblies for gene delivery : Chemical challenges in the creation of artificial viruses2012
- Author(s)
  K. Miyata, N. Nishiyama, K. Kataoka
- Journal Title
  
  Chem. Soc. Rev
  
  Volume: 41(7) Issue: 7 Pages: 2562-2574
- DOI
  10.1039/c1cs15258k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489
[Journal Article] Evaluation of intracellular trafficking and clearance from HeLa cells of doxorubic in-bound block copolymers2012
- Author(s)
  K.Sakai-Kato, N.Nishiyama, et al.
- Journal Title
  
  Int.J.Pharm.
  
  Volume: 423 Issue: 2 Pages: 401-409
- DOI
  10.1016/j.ijpharm.2011.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain2012
- Author(s)
  T.Suma, N.Nishiyama, et al
- Journal Title
  
  Biomaterials
  
  Volume: 33 Issue: 9 Pages: 2770-2779
- DOI
  10.1016/j.biomaterials.2011.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] Micellization of cisplatin (NC-6004) reduces its ototoxicity in guinea pigs2012
- Author(s)
  M.Baba, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release
  
  Volume: 157 Issue: 1 Pages: 112-117
- DOI
  10.1016/j.jconrel.2011.07.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23390393, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-23791880
[Journal Article] Effective transgene expression without toxicity by intraperitoneal administration of PEGdetachable polyplex micelles in mice with peritoneal dissemination2012
- Author(s)
  Kumagai 1VI, Shimoda S, Wakabayashi R, Kunisawa Y, Ishii T, Osada 1 Itaka K, Nishiyama N, Kataoka K and Nakano K
- Journal Title
  
  J Control Release
  
  Volume: (in press, 2012)
- Data Source
  KAKENHI-PROJECT-21390374
[Journal Article] Polymeric micelles incorporating (1,2-diaminocyclohexane) platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis2012
- Author(s)
  Md Rafi, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release
  
  Volume: (in press)(印刷中)(掲載確定)(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390009
[Journal Article] Polymeric micelles incorporating (1,2-diaminocyclohexane) platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis2012
- Author(s)
  Md Rafi, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release
  
  Volume: (in press)(印刷中)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Effective transgene expression without toxicity by intraperitoneal administration of PEG-detachable polyplex micelles in mice with peritoneal dissemination2012
- Author(s)
  M.Kumagai, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release
  
  Volume: (in press)(印刷中)(掲載確定) Issue: 3 Pages: 542-551
- DOI
  10.1016/j.jconrel.2012.03.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22659111, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23390009
[Journal Article] デンドリマー型光増感剤内包高分子ミセルを用いたPDT,PDD2012
- Author(s)
  比留間瞳, 守本祐司, 宮崎幸造, 井上明季, 野本貴大, 福島重人, 四ノ宮成祥, 西山伸宏, 片岡一則
- Journal Title
  
  日本レーザー医学会誌
  
  Volume: 33(2) Pages: 104-109
- NAID
  10031120443
- Data Source
  KAKENHI-PROJECT-23300174
[Journal Article] A novel homogeneous irradiation fiber probe for whole bladder wall photodynamic therapy2012
- Author(s)
  Miyazaki K, Morimoto Y, Nishiyama N, Maekawa Y, Hu WZ, Nakatate K, Kaneda K, Shinomiya N, Kataoka K
- Journal Title
  
  Lasers Surg Med
  
  Volume: 44(5) Pages: 413-420
- Data Source
  KAKENHI-PROJECT-23300174
[Journal Article] ドラッグデリバリーシステムと光ファイバー技術を融合した光線力学治療2012
- Author(s)
  守本祐司, 西山伸宏, 片岡一則
- Journal Title
  
  光学
  
  Volume: 41(11) Pages: 561-567
- Data Source
  KAKENHI-PROJECT-23300174
[Journal Article] Polylex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery2011
- Author(s)
  M.Oba, K.Miyata, K.Osada, R.J.Christie, M.Sanjoh, W.Li, S.Fukushima, T.Ishii, M.R.Kano, N.Nishiyama, H.Koyama, K.Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 32(2) Issue: 2 Pages: 652-663
- DOI
  10.1016/j.biomaterials.2010.09.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689024, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22390244, KAKENHI-PROJECT-22750098
[Journal Article] Disulfide crosslinked polyion complex micelles encapsulating dendrimer phthalocyanine directed to improved efficiency of photodynamic therapy2011
- Author(s)
  S.Herlambang, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release
  
  Volume: 155 Issue: 3 Pages: 449-457
- DOI
  10.1016/j.jconrel.2011.06.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] Gene transfer using micellar nanovectors inhibits corneal neovascularization in vivo2011
- Author(s)
  A. Iriyama, T. Usui, Y. Yanagi, S. Amano, M. Oba, K. Miyata, N. Nishiyama, K. Kataoka
- Journal Title
  
  Cornea
  
  Volume: 30(12) Issue: 12 Pages: 1423-1427
- DOI
  10.1097/ico.0b013e318206c893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049
[Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles.2011
- Author(s)
  Y.Vachutinsky, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release
  
  Volume: 149 Pages: 51-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Effect of polymer structure on micelles formed between siRNA and cationic block copolymer Comprising thiols and amidines2011
- Author(s)
  R. J. Christie, K. Miyata, Y. Matsumoto, T. Nomoto, D. Menasco, T.-C. Lai, M. Pennisi, K. Osada, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  Biomacromolecules
  
  Volume: 12(9) Issue: 9 Pages: 3174-3185
- DOI
  10.1021/bm2006714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
[Journal Article] Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting.2011
- Author(s)
  M.Murakami, N.Nishiyama, et al.
- Journal Title
  
  Science Transl.Med.
  
  Volume: 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging2011
- Author(s)
  F.M.Konig, Y.Vachutinsky, M.Oba, K.Miyata, N.Nishiyama, K.Kataoka, C.Brauchle, N.Ruthardt
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 151(2) Issue: 3 Pages: 104-109
- DOI
  10.1016/j.jconrel.2011.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689024, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] Disulfide crosslinked polyion complex micelles encapsulating dendrimer phthalocyanine directed to improved efficiency of photodynamic therapy2011
- Author(s)
  Herlambang S, Kumagai M, Nomoto T, Horie S, Fukushima S, Oba M, Miyazaki K, Morimoto Y, Nishiyama N, Kataoka K
- Journal Title
  
  J Control Release
  
  Volume: 155(3) Pages: 449-457
- Data Source
  KAKENHI-PROJECT-23300174
[Journal Article] Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles2011
- Author(s)
  H.Uchida, N.Nishiyama, et al
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: 133 Issue: 39 Pages: 15524-15532
- DOI
  10.1021/ja204466y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size2011
- Author(s)
  H. Cabral, Y. Matsumoto, K. Mizuno, Q. Chen, M. Murakami, M. Kimura, Y. Terada, M. R. Kano, K. Miyazono, M. Uesaka, N. Nishiyama, K. Kataoka
- Journal Title
  
  Nature Nanotech
  
  Volume: 6(12) Issue: 12 Pages: 815-823
- DOI
  10.1038/nnano.2011.166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
[Journal Article] Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery.2011
- Author(s)
  M.Oba, N.Nishiyama, et al.
- Journal Title
  
  Biomaterials
  
  Volume: 32 Pages: 652-663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Supramolecular nanodevices : From design validation to theranostic nanomedicine. Acc2011
- Author(s)
  H. Cabral, N. Nishiyama, K. Kataoka
- Journal Title
  
  Chem. Res
  
  Volume: 44(10) Issue: 10 Pages: 999-1008
- DOI
  10.1021/ar200094a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Gene transfer using micellar nanovectors inhibits choroidal neovascularization in vivo2011
- Author(s)
  A. Iriyama, M. Oba, T. Ishii, N. Nishiyama, K. Kataoka, Y. Tamaki, Y. Yanagi
- Journal Title
  
  PLoS One
  
  Volume: 6(12) Issue: 12 Pages: e28560-e28560
- DOI
  10.1371/journal.pone.0028560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] In situ quantitative monitoring of polyplexes and polyplex Micelles in the blood circulation using intravital real-time confocal laser scanning microscopy2011
- Author(s)
  T.Nomoto, Y.Matsumoto, K.Miyata, M.Oba, S.Fukushima, N.Nishiyama, T.Yamasoba, K.Kataoka
- Journal Title
  
  J.Control.Release
  
  Volume: 151(2) Issue: 2 Pages: 104-109
- DOI
  10.1016/j.jconrel.2011.02.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
[Journal Article] PEG-detachable cationic polyaspartamide detivatives bearing stearoyl moieties for systemic siRNA delivery toward subcutaneous BxPC3 pancreatic tumor2011
- Author(s)
  H.-J.Kim, N.Nishiyama, et al
- Journal Title
  
  J.Drug Target.
  
  Volume: 20 Issue: 1 Pages: 33-42
- DOI
  10.3109/1061186x.2011.632010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
[Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles2011
- Author(s)
  Y. Vachutinsky, M. Oba, K. Miyata, S. Hiki, M. R. Kano, N. Nishiyama, H. Koyama, K. Miyazono, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 149(1) Issue: 1 Pages: 51-57
- DOI
  10.1016/j.jconrel.2010.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity2011
- Author(s)
  F. Pittella, M. Zhang, Y. Lee, H.-J. Kim, T. Tockary, K. Osada, T. Ishii, K. Miyata, N. Nishiyama
- Journal Title
  
  Biomaterials
  
  Volume: 32(11) Issue: 11 Pages: 3106-3114
- DOI
  10.1016/j.biomaterials.2010.12.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23390009
[Journal Article] Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting2011
- Author(s)
  M. Murakami, H. Cabral, Y. Matsumoto, S. Wu, M. R. Kano, T. Yamori, N. Nishiyama, K. Kataoka
- Journal Title
  
  Science Transl. Med
  
  Volume: 3(64) Issue: 64 Pages: 64-64
- DOI
  10.1126/scitranslmed.3001385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22240092
[Journal Article] Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown2010
- Author(s)
  H.-J. Kim, A. Ishii, K. Miyata, Y. Lee, S. Wu, M. Oba, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 145(2) Issue: 2 Pages: 141-148
- DOI
  10.1016/j.jconrel.2010.03.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489
[Journal Article] siRNA-grafted polymer for polyion complex(PIC)-based siRNA delivery : Enhancement of PIC stability and gene silencing efficiency2010
- Author(s)
  H. Takemoto, A. Ishii, K. Miyata, M. Nakanishi, M. Oba, T. Ishii, Y. Yamasaki, N. Nishiyama, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 31(31) Issue: 31 Pages: 8097-8105
- DOI
  10.1016/j.biomaterials.2010.07.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489
[Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA.2010
- Author(s)
  K.Miyata, N.Nishiyama, et al.
- Journal Title
  
  Biomaterials
  
  Volume: 31 Pages: 4764-4770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Visible-drug delivery by supra-molecular nanocarriers directing to single-platformed diagnosis and therapy of pancreatic tumor model2010
- Author(s)
  S. Kaida, H. Cabral, M. Kumagai, A. Kishimura, Y. Terada, M. Sekino, I. Aoki, N. Nishiyama, T. Tani, K. Kataoka
- Journal Title
  
  Cancer Res
  
  Volume: 70(18) Issue: 18 Pages: 7031-7041
- DOI
  10.1158/0008-5472.can-10-0303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA.2010
- Author(s)
  K.Miyata, N.Nishiyama, et al.
- Journal Title
  
  Biomaterials 31
  
  Pages: 4764-4770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA2010
- Author(s)
  K. Miyata, N. Gouda, H. Takemoto, M. Oba, Y. Lee, H. Koyama, Y. Yamasaki, K. Itaka, N. Nishiyama, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 31(17) Issue: 17 Pages: 4764-4770
- DOI
  10.1016/j.biomaterials.2010.02.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles.2010
- Author(s)
  Y.Vachutinsky, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release (in press, (印刷中)掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Enhanced In vivo magnetic resonance imaging of tumors by PEGylatediron oxide-gold core-shell nanoparticles with prolonged blood circulation properties.2010
- Author(s)
  M.Kumagai, N.Nishiyama, et al.
- Journal Title
  
  Macromol.Rapid Commun.
  
  Volume: 31 Pages: 1521-1528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010
- Author(s)
  M. Oba, Y. Vachutinsky, K. Miyata, M. R. Kano, S. Ikeda, N. Nishiyama, K. Itaka, K. Miyazono, H. Koyama, K. Kataoka
- Journal Title
  
  Mol. Pharm
  
  Volume: 7(2) Issue: 2 Pages: 501-509
- DOI
  10.1021/mp9002317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22390244
[Journal Article] Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles2010
- Author(s)
  Y.Lee, N.Nishiyama, et al.
- Journal Title
  
  Angew.Chem.Int.Ed. 49
  
  Pages: 2552-2555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles2010
- Author(s)
  Y.Vachutinsky, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release (in press, (印刷中)掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010
- Author(s)
  M.Oba, N.Nishiyama, et al.
- Journal Title
  
  Molecular Pharmaceutics (in press, (印刷中)掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown.2010
- Author(s)
  H.-J.Kim, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release
  
  Volume: 145 Pages: 141-148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Direct and instantaneous observation of intravenously injected substances using intravital confocal micro-videography.2010
- Author(s)
  Y.Matsumoto, N.Nishiyama, et al.
- Journal Title
  
  Biomed.Opt.Express
  
  Volume: 1 Pages: 1209-1216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles.2010
- Author(s)
  Y. Lee, T. Ishii, H. -J. Kim, N. Nishiyama, Y. Hayakawa, K. Itaka, K. Kataoka
- Journal Title
  
  Angew. Chem. Int. Ed. 49(14)
  
  Pages: 2552-2555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Visible-drug delivery by supra-molecular nanocarriers directing to single-platformed diagnosis and therapy of pancreatic tumor model.2010
- Author(s)
  S.Kaida, N.Nishiyama, et al.
- Journal Title
  
  Cancer Research
  
  Volume: 70 Pages: 7031-7041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] siRNA-based therapy ameliorates glomerulonephritis2010
- Author(s)
  H. Shimizu, Y. Hori, S. Kaname, K. Yamada, N. Nishiyama, S. Matsumoto, K. Miyata, M. Oba, A. Yamada, K. Kataoka, T. Fujita
- Journal Title
  
  J. Am. Soc. Nephrol
  
  Volume: 21(4) Issue: 4 Pages: 622-633
- DOI
  10.1681/asn.2009030295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-1.2010
- Author(s)
  M. Oba, Y. Vachutinsky, K. Miyata, M.R. Kano, S. Ikeda, N. Nishiyama, K. Itaka, K. Miyazono, H. Koyama, K. Kataoka
- Journal Title
  
  Mol. Pharm. 7(2)
  
  Pages: 501-509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] siRNA-grafted polymer for polyion complex (PIC)-based siRNA delivery : Enhancement of PIC stability and gene silencing efficiency.2010
- Author(s)
  H.Takemoto, N.Nishiyama, et al.
- Journal Title
  
  Biomaterials
  
  Volume: 31 Pages: 8097-8105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles.2010
- Author(s)
  Y.Lee, N.Nishiyama, et al.
- Journal Title
  
  Angew.Chem.Int.Ed. 49
  
  Pages: 2552-2555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010
- Author(s)
  M.Oba, N.Nishiyama, et al.
- Journal Title
  
  Molecular Pharmaceutics (in press, (印刷中)掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA.2010
- Author(s)
  K. Miyata, N. Gouda, H. Takemoto, M. Oba, Y. Lee, H. Koyama, Y. Yamasaki, K. Itaka, N. Nishiyama, K. Kataoka
- Journal Title
  
  Biomaterials 31(17)
  
  Pages: 4764-4770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Efficient delivery of bioactive antibodies into thecytoplasm of living cells by charge-conversional polyion complex micelles. Angew2010
- Author(s)
  Y. Lee, T. Ishii, H.-J. Kim, N. Nishiyama, Y. Hayakawa, K. Itaka, K. Kataoka
- Journal Title
  
  Chem. Int. Ed
  
  Volume: 49(14) Issue: 14 Pages: 2552-2555
- DOI
  10.1002/anie.200905264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010
- Author(s)
  M. Oba, Y. Vachutinsky, K. Miyata, M.R. Kano, S. Ikeda, N. Nishiyama, K. Itaka, K. Miyazono, H. Koyama, K. Kataoka
- Journal Title
  
  Mol. Pharm 7(2)
  
  Pages: 501-509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Design and development of dendrimer photosensitizer- incorporated polymeric micelles for enhanced photodynamic therapy.2009
- Author(s)
  N. Nishiyama, Y. Morimoto, W. -D. Jang, K. Kataoka
- Journal Title
  
  Adv. Drug Deliv. Rev. 61(4)
  
  Pages: 327-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats2009
- Author(s)
  M.Harada-Shiba, N.Nishiyama, et al.
- Journal Title
  
  Molecular Ther. 17
  
  Pages: 1180-1186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine.2009
- Author(s)
  N. Nishiyama, Y. Nakagishi, Y. Morimoto, P. -S. Lai, K. Miyazaki, K. Urano, S. Horie, M. Kumagai, S. Fukushima, Y. Cheng, W. -D. Jang, M. Kikuchi, K. Kataoka
- Journal Title
  
  J. Control. Release 133(3)
  
  Pages: 245-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles2009
- Author(s)
  M. Han, M. Oba, N. Nishiyama, M. R. Kano, S. Kizaka-Kondoh, K. Kataoka
- Journal Title
  
  Mol. Ther
  
  Volume: 17(8) Issue: 8 Pages: 1404-1410
- DOI
  10.1038/mt.2009.119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats2009
- Author(s)
  M. Harada-Shiba, I. Takamisawa, K. Miyata, T. Ishii, N. Nishiyama, K. Itaka, K. Kangawa, F. Yoshihara, Y. Asada, K. Hatakeyama, N. Nagaya, K. Kataoka
- Journal Title
  
  Mol. Ther
  
  Volume: 17(7) Issue: 7 Pages: 1180-1186
- DOI
  10.1038/mt.2009.63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats.2009
- Author(s)
  M.Harada-Shiba, N.Nishiyama, et al.
- Journal Title
  
  Molecular Ther. 17
  
  Pages: 1180-1186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Charge-conversional polyionic complex micellesefficient nanocarriers for protein delivery into cytoplasm2009
- Author(s)
  Y. Lee, N. Nishiyama, et.al.
- Journal Title
  
  Angew. Chem. Int. Ed. (in press)(印刷中)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles2009
- Author(s)
  M.Han, N.Nishiyama, et al.
- Journal Title
  
  Angew.Chem.Int.Ed. 17
  
  Pages: 1404-1410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine2009
- Author(s)
  N. Nishiyama, K. Kataoka, et.al.
- Journal Title
  
  J. Control. Release 133
  
  Pages: 245-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block-copolymer-coated magnetite nanoparticles with TGF-beta inhibitor2009
- Author(s)
  M. Kumagai, M.R. Kano, Y. Morishita, M. Ota, Y. Imai, N. Nishiyama, M. Sekino, S. Ueno, K. Miyazono, K. Kataoka
- Journal Title
  
  J. Control. Release 140(3)
  
  Pages: 306-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block-copolymer-coated magnetite nanoparticles combined with TGF-beta inhibitor.2009
- Author(s)
  M.Kumagai, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release 140
  
  Pages: 306-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm.2009
- Author(s)
  Y. Lee, T. Ishii, H. Cabral, H. -J. Kim, J. -H. Seo, N. Nishiyama, H. Oshima, K. Osada, K. Kataoka
- Journal Title
  
  Angew. Chem. Int. Ed. 48(29)
  
  Pages: 5309-5312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine.2009
- Author(s)
  N. Nishiyama, K. Kataoka, et al. et al.
- Journal Title
  
  J. Control. Release 133
  
  Pages: 245-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240046
[Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles.2009
- Author(s)
  M. Han, M. Oba, N. Nishiyama, M.R. Kano, S. Kizaka-Kondoh, K. Kataoka
- Journal Title
  
  Mol. Ther. 17(8)
  
  Pages: 1404-1410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles.2009
- Author(s)
  M.Han, N.Nishiyama, et al.
- Journal Title
  
  Angew.Chem.Int.Ed. 17
  
  Pages: 1404-1410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] PEGylated calcium phosphate nanocomposites as smart environment-sensitive carriers for siRNA delivery2009
- Author(s)
  M.Zhang, N.Nishiyama, et al.
- Journal Title
  
  Advanced Materials 21
  
  Pages: 3520-3525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] A photoactivated targeting chemotherapy using glutathione sensitive camptothecin-Ioaded polymeric micelles2009
- Author(s)
  H. Cabral, N. Nishiyama, et.al.
- Journal Title
  
  Pharm. Res. 26
  
  Pages: 82-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery2009
- Author(s)
  S. Matsumoto, R. J. Christie, N. Nishiyama, K. Miyata, A. Ishii, M. Oba, H. Koyama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  Biomacromolecules
  
  Volume: 10(1) Issue: 1 Pages: 119-127
- DOI
  10.1021/bm800985e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block-copolymer-coated magnetite nanoparticles combined with TGF-beta inhibitor2009
- Author(s)
  M.Kumagai, N.Nishiyama, et al.
- Journal Title
  
  J.Control.Release 140
  
  Pages: 306-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles2009
- Author(s)
  M. Han, M. Oba, N. Nishiyama, M.R. Kano, S. Kizaka-Kondoh, K. Kataoka
- Journal Title
  
  Mol. Ther. 17(8)
  
  Pages: 1404-1410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] PEGylated calcium phosphate nanocomposites as smart environment-sensitive carriers for siRNA delivery2009
- Author(s)
  M.Zhang, N.Nishiyama, et al.
- Journal Title
  
  Advanced Materials 21
  
  Pages: 3520-3525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA2009
- Author(s)
  K.Miyata, N.Nishiyama, et al.
- Journal Title
  
  Biomaterials 31
  
  Pages: 4764-4770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery2009
- Author(s)
  S. Matsumoto, N. Nishiyama, et.al.
- Journal Title
  
  Biomacromolecules 10
  
  Pages: 119-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] PEGylated calcium phosphate nanocomposites as smart environment-sensitive carriers for siRNA delivery2009
- Author(s)
  M. Zhang, A. Ishii, N. Nishiyama, S. Matsumoto, T. Ishii, Y. Yamasaki, K. Kataoka
- Journal Title
  
  Adv. Mater
  
  Volume: 21(34) Issue: 34 Pages: 3520-3525
- DOI
  10.1002/adma.200800448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm2009
- Author(s)
  Y. Lee, T. Ishii, H. Cabral, H.-J. Kim, J.-H. Seo, N. Nishiyama, H. Oshima, K. Osada, K. Kataoka
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 48(29) Issue: 29 Pages: 5309-5312
- DOI
  10.1002/anie.200900064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659299
[Journal Article] A photo-activated targeting chemotherapy using glutathione sensitive camptothecin-loaded polymeric micelles.2009
- Author(s)
  H. Cabral, M. Nakanishi, M. Kumagai, W. -D. Jang, N. Nishiyama, K. Kataoka
- Journal Title
  
  Pharm. Res. 26(1)
  
  Pages: 82-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotalineinduced pulmonary hypertension in rats2009
- Author(s)
  M. HaradaShiba, N. Nishiyama, et.al.
- Journal Title
  
  Molecular Ther. (in press)(印刷中)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors2008
- Author(s)
  S. Takae, K. Miyata, M. Oba, T. Ishii, N. Nishiyama, K. Itaka, Y. Yamasaki, H. Koyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc. 130(18)
  
  Pages: 6001-6009
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive non-viral gene vectors.2008
- Author(s)
  S. Takae, N. Nishiyama, et. al.
- Journal Title
  
  J.Am.Chem.Soc. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Polyplexes from poly(aspartamide) bearing 1, 2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity.2008
- Author(s)
  K. Miyata, M. Oba, M. Nakanishi, S. Fukushima, Y. Yamasaki, H. Koyama, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc. 130(48)
  
  Pages: 16287-16294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Charge-conversional ternary polyplex with endosome disruption moiety: a new paradaigm for the efficient and safe gene delivery.2008
- Author(s)
  Y. Lee, K. Miyata, M. Oba, T. Ishii, S. Fukushima, M. Han, N. Nishiyama, K. Kataoka
- Journal Title
  
  Angew. Chem., Int. Ed. 47(28)
  
  Pages: 5163-5166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhancement of Angiogenesis through Stabilization of Hypoxia Inducible Factor-1 by Silencing Proly1 Hydroxylase Domain 2 Gene2008
- Author(s)
  S, Wu, N. Nishiyama, et. al.
- Journal Title
  
  Mol. Ther. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking2008
- Author(s)
  M. Oba, K. Aoyagi, K. Miyata, Y. Matsumoto, K. Itaka, N. Nishiyama, Y. Yamasaki, H. Koyama, K. Kataoka
- Journal Title
  
  Mol. Pharm. 5(6)
  
  Pages: 1080-1092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Polyplex micelles with cyclic RGD peptide ligands and disulfide crosslinks directing to the enhanced transfection via controlled intracellular trafficking2008
- Author(s)
  M. Oba, N. Nishiyama, et.al.
- Journal Title
  
  Mol. Pharm. 5
  
  Pages: 1080-1092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive non-viral gene vectors.2008
- Author(s)
  S. Takae, K. Miyata, M. Oba, T. Ishii, N. Nishiyama, K. Itaka, Y. Yamasaki, H. Koyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc. 130(18)
  
  Pages: 6001-6009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor2008
- Author(s)
  K. Miyata, M. Oba, M.R. Kano, S. Fukushima, Y. Vachutinsky, M. Han, H. Koyama, K. Miyazono, N. Nishiyama, K. Kataoka
- Journal Title
  
  Pharm. Res. 25(12)
  
  Pages: 2924-2936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Photodynamic therapy for corneal neovascularization using polymericmicelles encapsulating dendrimer porphyrins2008
- Author(s)
  K. Sugisaki, N. Nishiyama, et. al.
- Journal Title
  
  Invest. Ophth. Vis. Sci. 49
  
  Pages: 894-899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor tissue.2008
- Author(s)
  K. Miyata, M. Oba, M.R. Kano, S. Fukushima, Y. Vachutinsky, M. Han, H. Koyama, K. Miyazono, N. Nishiyama, K. Kataoka
- Journal Title
  
  Pharm. Res. 25(12)
  
  Pages: 2924-2936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Polyplexes from poly(aspartamide) bearing 1, 2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity2008
- Author(s)
  K. Miyata, M. Oba, M. Nakanishi, S. Fukushima, Y. Yamasaki, H. Koyama, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc. 130(48)
  
  Pages: 16287-16294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to nancreatic tumor tissue2008
- Author(s)
  K. Miyata, N. Nishiyama, et.al.
- Journal Title
  
  Pharm. Res. 25
  
  Pages: 2924-2936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Polyplexes from poly(aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity2008
- Author(s)
  K. Miyata, N. Nishiyama, et.al.
- Journal Title
  
  J. Am. Chem. Soc. 130
  
  Pages: 16287-16294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Charge-conversional ternary polyplex with endosome disruption moiety : a new paradaigm for the efficient and safe gene delivery2008
- Author(s)
  Y. Lee, N. Nishiyama, et.al.
- Journal Title
  
  Angew. Chem., Int. Ed. 47
  
  Pages: 5163-5166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhancement of angiogenesis through stabilization of hypoxia inducible factor-1 by silencing prolyl hydroxylase domain 2 gene2008
- Author(s)
  S. Wu, N. Nishiyama, et.al.
- Journal Title
  
  Angew. Chem., Int. Ed. 16
  
  Pages: 1227-1234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation2007
- Author(s)
  D. Akagi, M. Oba, H. Koyama, N. Nishiyama, S. Fukushima, T. Miyata, H. Nagawa, K. Kataoka
- Journal Title
  
  Gene Ther. 14(13)
  
  Pages: 1029-1038
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy.2007
- Author(s)
  K. Miyata, N. Nishiyama, et. al.
- Journal Title
  
  J. Control. Release 122
  
  Pages: 252-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly (ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes2007
- Author(s)
  M. Oishi, Y. Nagasaki, N. Nishiyama, K. Itaka, M. Takagi, A. Shimamoto, Y. Furuichi, K. Kataoka
- Journal Title
  
  ChemMedChem 2(9)
  
  Pages: 1290-1297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-signaling.2007
- Author(s)
  M.R. Kano, Y. Bae, C. Iwata, Y. Morishita, M. Yashiro, M. Oka, T. Fujii, A. Komuro, K. Kiyono, M. Kaminishi, K. Hirakawa, Y. Ouchi, N. Nishiyama, K. Kataoka, K. Miyazono
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A. 104(9)
  
  Pages: 3460-3465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-signaling2007
- Author(s)
  Kano, MR, Nishiyama, N et al.
- Journal Title
  
  Proc. Natl. Acad. Sci., USA 104(9)
  
  Pages: 3460-3465
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Biocompatible micellar nanovectors achieve efficient gene transfer tovascular lesions without cytotoxicity and thrombus formation.2007
- Author(s)
  D. Akagi, N. Nishiyama, et. al.
- Journal Title
  
  Gene Ther. 14
  
  Pages: 1029-1038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy2007
- Author(s)
  K. Miyata, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  J. Control. Release 122(3)
  
  Pages: 252-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Optimization of (1,2-diamino-cyclohexane) platinum (II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.2007
- Author(s)
  H. Cabral, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release 121
  
  Pages: 146-155
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591578
[Journal Article] Gene delivery with biocompatible cationic polymer: Pharmacogenomic analysis on cell bioactivity.2007
- Author(s)
  K. Masago, N. Nishiyama, et. al.
- Journal Title
  
  Biomaterials 28
  
  Pages: 5169-5175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-signaling2007
- Author(s)
  Kano, MR, Nishiyama, N et al.
- Journal Title
  
  Proc. Natl. Acad. Sci., USA 104(9)
  
  Pages: 3460-3465
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Transfection Study Using Multicellular Tumor Spheroids for Screening Non-viral Polymeric Gene Vectors with Low Cytotoxicity and High Transfection Efficiencies.2007
- Author(s)
  M. Han, N. Nishiyama, et. al.
- Journal Title
  
  Bioconjugate Chem. 121
  
  Pages: 38-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer.2007
- Author(s)
  N. Nishiyama, K. Kataoka et al.
- Journal Title
  
  Nature Mater. 4
  
  Pages: 934-941
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Optimization of (1, 2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.2007
- Author(s)
  H. Cabral, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release 121(3)
  
  Pages: 146-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-betasignaling.2007
- Author(s)
  M. R. Kano, N. Nishiyama, et. al.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 104
  
  Pages: 3460-3465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] In Vivo Antitumor Activity of the Folate-Conjugated pH-Sensitive Polymeric Micelle Selectively Releasing Adriamycin in the Intracellular Acidic Compartments.2007
- Author(s)
  Y. Bae, N. Nishiyama, et. al.
- Journal Title
  
  J. Control. Release 18
  
  Pages: 1131-1139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation2007
- Author(s)
  Aakagi, D., Nishiyama, N.et al.
- Journal Title
  
  Gene Therapy (in press)
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments2007
- Author(s)
  Y. Bae, N. Nishiyama, K. Kataoka
- Journal Title
  
  Bioconjugate Chem. 18(4)
  
  Pages: 1131-1139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Optimization of (1,2-diamino-cyclohexane) platinum(II)-loaded polymeric micelles directedto improved tumor targeting and enhanced antitumor activity.2007
- Author(s)
  H. Cabral, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release 121
  
  Pages: 146-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591578
[Journal Article] Kataoka, Supramolecular nanocarriers integrated with dendrimers encapsulating photosensitizers for effective photodynamic therapy and photochemical gene delivery.2007
- Author(s)
  N. Nishiyama, K. Kataoka, et. al.
- Journal Title
  
  New J. Chem. 31
  
  Pages: 1074-1082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy.2007
- Author(s)
  K. Miyata, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  J. Control. Release 122(3)
  
  Pages: 252-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling2007
- Author(s)
  M. R. Kano, Y. Bae, C. Iwata, Y. Morishita, M. Yashiro, M. Oka, T. Fujii, A. Komuro, K. Kiyono, M. Kamiishi, K. Hirakawa, Y. Ouchi, N. Nishiyama, K. Kataoka, K. Miyazono
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 104(9)
  
  Pages: 3460-3465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Dendrimer Generation Effects on Photodynamic Efficacy of Dendrimer Porphyrins and Dendrimer-Loaded Supramolecular Nanocarrier2007
- Author(s)
  Y. Li, N. Nishiyama, et. al.
- Journal Title
  
  Chem.Mater. 19
  
  Pages: 5557-5562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] pH-Responsive Multi-PEGylated Dual Cationic Nanoparticles Enable Charge Modulations for Safe Gene Delivery.2007
- Author(s)
  M. P. Xiong, N. Nishiyama, et. al.
- Journal Title
  
  ChemMedChem 2
  
  Pages: 1321-1327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Preparation of naphthalocyanine dendrimer loaded polyion complex micelle for photodynamic therapy.2007
- Author(s)
  W. -D. Jang, N. Nishiyama, et. al.
- Journal Title
  
  Key Eng. Mater. 342-343
  
  Pages: 465-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins.2007
- Author(s)
  M. Oba, K. N. Nishiyama, et. al.
- Journal Title
  
  Bioconjugate Chem. 18
  
  Pages: 1415-1423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] Dendrimer generation effects on photodynamic efficacy of dendrimer porphyrins and dendrimer-loaded supramolecular nanocarriers2007
- Author(s)
  Y. Li, W. -D. Jang, N. Nishiyama, A. Kishimura, S. Kawauchi, Y. Morimoto, S. Miake, T. Yamashita, M. Kikuchi, T. Aida, K. Kataoka
- Journal Title
  
  Chem. Mater. 19(23)
  
  Pages: 5557-5562
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-signaling2007
- Author(s)
  Kano, M.R., Nishiyama, N.et al.
- Journal Title
  
  Proc.Natl.Acad.Sci., USA 104(9)
  
  Pages: 3460-3465
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins2007
- Author(s)
  M. Oba, S. Fukushima, N. Kanayama, K. Aoyagi, N. Nishiyama, H. Koyama, K. Kataoka
- Journal Title
  
  Bioconjugate Chem. 18(5)
  
  Pages: 1415-1423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Optimization of(1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.2007
- Author(s)
  H. Cabral, N. Nishiyama, et. al.
- Journal Title
  
  J. Control. Release 121
  
  Pages: 146-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] In Vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments.-2007
- Author(s)
  Bae Y, Nishiyama N, Kataoka K
- Journal Title
  
  Bioconjugate Chemistry 18
  
  Pages: 1131-1139
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591578
[Journal Article] Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies2007
- Author(s)
  M. Han, Y. Bae, N. Nishiyama, K. Miyata, M. Oba, K. Kataoka
- Journal Title
  
  J. Control. Release 121(1-2)
  
  Pages: 38-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Enhanced Growth Inhibition of Hepatic Multicellular Tumor Spheroids by Lactosylated Pol(ethylene glycol)-siRNA Conjugate Fotmulated in PEGylated Polyplexes.2007
- Author(s)
  M. Oishi, N. Nishiyama, et. al.
- Journal Title
  
  ChemMedChem 2
  
  Pages: 1290-1297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy2007
- Author(s)
  K. Miyata, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  J. Control. Release 122(3)
  
  Pages: 252-260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Kataoka, Supramolecular nanocarriers integrated with dendrimers encapsulating photosensitizers for effective photodynamic therapy and photochemical gene delivery.2007
- Author(s)
  N. Nishiyama, et. al.
- Journal Title
  
  New J. Chem. 31
  
  Pages: 1074-1082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19680026
[Journal Article] In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments2007
- Author(s)
  Y. Bae, N. Nishiyama, K. Kataoka
- Journal Title
  
  Bioconjugate Chem. 18(4)
  
  Pages: 11311139-11311139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Optimization of (1, 2-diamino- cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity2007
- Author(s)
  H. Cabral, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release 121(3)
  
  Pages: 146-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling2007
- Author(s)
  M.R. Kano, Y. Bae, C. Iwata, Y. Morishita, M. Yashiro, M. Oka, T. Fujii, A. Komuro, K. Kiyono, M. Kaminishi, K. Hirakawa, Y. Ouchi, N. Nishiyama, K. Kataoka, K. Miyazono
- Journal Title
  
  P. Natl. Acad. Sci. USA. 104(9)
  
  Pages: 3460-3465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Optimization of (1,2-diamino-cyclohexane) platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity2007
- Author(s)
  H. Cabral, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Control. Release 121(3)
  
  Pages: 146-155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Polyion complex micelles for photodynamic therapy : incorporation of dendritic photosensitizer excitable atlong wavelength relevant to improved tissue-penetrating property2006
- Author(s)
  W. -D. Jang, Y. Nakagishi, N. Nishiyama, S. Kawauchi, Y. Morimoto, M. Kikuchi, K. Kataoka
- Journal Title
  
  J. Cotrol. Release 113(1)
  
  Pages: 73-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] PEGylated gene nanocarriers based on block catiomers bearing ethylenediamine repeating units directed to remarkable enhancement of photochemical transfection2006
- Author(s)
  Arnida, Nishiyama, N.et al.
- Journal Title
  
  Journal of Controlled Release 115(2)
  
  Pages: 208-215
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery2006
- Author(s)
  Nishiyama, N.et al.
- Journal Title
  
  Pharmacology ＆ Therapeutics 112(3)
  
  Pages: 630-648
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Polyion complex micelle for photodynamic therapy : incorporation of dendritic photosensitizer excitable at long wavelength with enhanced cellular uptake2006
- Author(s)
  Jang, W.D., Nishiyama, N.et al.
- Journal Title
  
  Journal of Controlled Release 113(1)
  
  Pages: 73-79
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Nanostructured devices based on block copolymer assemblies for drug delivery : designing structures for enhanced drug function2006
- Author(s)
  N.Nishiyama, K.Kataoka
- Journal Title
  
  Adv.Polym.Sci.(Polymer Therapeutics II) 193
  
  Pages: 67-101
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells2006
- Author(s)
  N. Kanayama, S. Fukushima, N. Nishiyama, K. Itaka, W. -D. Jang, K. Miyata, Y. Yamasaki, U. -I. Chung, K. Kataoka
- Journal Title
  
  ChemMedChem 1(4)
  
  Pages: 439-444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Photochemical enhancement of transgene expression by polymeric micelles incorporating plasmid DNA and dendrimer-based photosensitizer2006
- Author(s)
  Nishiyama, N.et al.
- Journal Title
  
  Journal of Drug Targeting 14(6)
  
  Pages: 413-424
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Nano-structured devices based on block copolymer assemblies for drug delivery: designing structures for enhanced drug function2005
- Author(s)
  Ideta, R., Nishiyama, N., et al.
- Journal Title
  
  Nano Letters 5(12)
  
  Pages: 2426-2431
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with poly(ethylene glycol) to enhance intracellular photodynamic efficacy.2005
- Author(s)
  Jang WD, Nishiyama N, Koyama H, Kataoka K et al.
- Journal Title
  
  Angew.Chem.Int.Ed.Engl 44
  
  Pages: 419-423
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery.2005
- Author(s)
  Y. Bae, W. -D. Jang, N. Nishiyama, S. Fukushima, K. Kataoka
- Journal Title
  
  Mol. BioSyst. 1(3)
  
  Pages: 242-250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with poly (ethylene glycol) to enhance ntracellular photodynamic efficacy2005
- Author(s)
  W. -D. Jang, N. Nishiyama, G. -D. Zhang, A. Harada, D. -L. Jiang, S. Kawauchi, Y. Morimoto, M. Kikuchi, H. Koyama, T. Aida, K. Kataoka, K. Kataoka
- Journal Title
  
  Angew. Chem. Int. Ed. 44(3)
  
  Pages: 419-423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Preparation and biological properties of dichloro (1,2-diaminocyclohexane) platinum(II)(DACHPt)-loaded polymeric micelles2005
- Author(s)
  H. Cabral, N. Nishiyama, S. Okazaki, H. Koyama, K. Kataoka
- Journal Title
  
  J. Control. Release 101(1-3)
  
  Pages: 223-232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005
- Author(s)
  Nishiyama, N., et al.
- Journal Title
  
  Nature Materials 4(12)
  
  Pages: 934-941
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005
- Author(s)
  N. Nishiyama, A. Iriyama, W. -D. Jang, K. Miyata, K. Itaka, Y. Inoue, H. Takahashi, Y. Yanagi, Y. Tamaki, H. Koyama, K. Kataoka
- Journal Title
  
  Nature Mater 4(12)
  
  Pages: 934-341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Suparmolecular nanocarrier of anionic dendrimer porphyrins with PEGylated cationic block copolymer to enhance intracellular photodynamic efficacy2005
- Author(s)
  Jang, W.-D., Nishiyama, N., et al.
- Journal Title
  
  Angewandte Chemie, International Edition 44(3)
  
  Pages: 419-423
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Freeze-dried formulations for in vivo gene delivery of PEGylated polyplex micelles with disulfide crosslinked cores to the liver2005
- Author(s)
  Miyata, K., Nishiyama, N., et al.
- Journal Title
  
  Journal of Controlled Release 109(1-3)
  
  Pages: 15-23
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles2005
- Author(s)
  Cabral H, Nishiyama N, Koyama H, Kataoka K et al.
- Journal Title
  
  J.Control.Release 101
  
  Pages: 223-232
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Nanotechnologh-based photodynamic therapy for neovascular disease using a supramolecular nanocarrier loaded with a dendritic photosensitizer2005
- Author(s)
  R. Ideta, F. Tasaka, W. -D. Jang, N. Nishiyama, G. -D. Zhang, A. Harada, Y. Yanagi, Y. Tamaki, T. Aida, K. Kataoka
- Journal Title
  
  Nano Lett. 5(12)
  
  Pages: 2426-2431
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Supramolecular nanocarrier of anionic dendrimer prophyrins with cationic block copolymers modified with poly(ethylene glycol) to enhance intracellular photodynamic efficacy.2005
- Author(s)
  Jang WD, Nishiyama N, Koyama H, Kataoka K, et al.
- Journal Title
  
  Angew. Chem. Int. Ed. Engl 44
  
  Pages: 419-423
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with polyethylene glycol to enhance intracellular photodynamic efficacy2005
- Author(s)
  Jang, W.-D., Nishiyama, N., et al.
- Journal Title
  
  Angewandte Chemie, International Edition 44(3)
  
  Pages: 419-423
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] PEGylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery2005
- Author(s)
  Fukushima, S., Nishiyama, N., et al.
- Journal Title
  
  Journal of the American Chemical Society 127(9)
  
  Pages: 2810-2811
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property : Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy2005
- Author(s)
  Y. Bae, N. Nishiyama, S. Fukushima, H. Koyama, Y. Matsumura, K. Kataoka
- Journal Title
  
  Bioconjugate Chem. 16(1)
  
  Pages: 122-130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with poly (ethylene glycol) to enhance intracellular photodynamic efficacy.2005
- Author(s)
  Jang WD, Nishiyama N, Koyama H, Kataoka K, et al.
- Journal Title
  
  Angew.Chem.Int.Ed.Engl 44
  
  Pages: 419-423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Smart polymeric micelles for gene and drug delivery2005
- Author(s)
  Nishiyama, N., et al.
- Journal Title
  
  Drug Discovery Today: Technologies 2(1)
  
  Pages: 21-26
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Lactosylated poly (ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells2005
- Author(s)
  M. Oishi, Y. Nagasaki, K. Itaka, N. Nishiyama, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc. 127(6)
  
  Pages: 1624-1625
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] PEGylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery2005
- Author(s)
  S. Fukushima, K. Miyata, N. Nishiyama, N. Kanayama, Y. Yamasaki, K. Kataoka
- Journal Title
  
  J. Am. Chem. Soc. 127(9)
  
  Pages: 2810-2811
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Multifunctional polymeric micelles with folate-mediated cancer cell argeting and pH-triggered drug releasing properties for active intracellular drug delivery2005
- Author(s)
  Y. Bae, W. -D. Jang, N. Nishiyama, S. Fukushima, K. Kataoka
- Journal Title
  
  Mol. BioSyst 1(3)
  
  Pages: 242-250
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Preparation and biological properties dichloro (1, 2-diaminocyclohexane) platinum (II) (DACHPt)-loaded polymeric micelles2005
- Author(s)
  Cabral H, Nishiyama N, Koyama H, Kataoka K, et al.
- Journal Title
  
  J.Contorol.Release 101
  
  Pages: 223-232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Preparation and biological characterization of polymeric micelle drug carries with intracellular pH-triggered property : Tumor permeability, controlled subsellular drug distribution, and enhanced in vivo antitumor efficacy2005
- Author(s)
  Bae Y, Nishiyama N, Koyama H, Kataoka K, et al.
- Journal Title
  
  Bioconjug. Chem. 16
  
  Pages: 122-130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property : Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy2005
- Author(s)
  Bae Y, Nishiyama N, Koyama H, Kataoka K et al.
- Journal Title
  
  Bioconjug.Chem. 16
  
  Pages: 122-130
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005
- Author(s)
  Nishiyama N, Koyama H, Kataoka K, et al.
- Journal Title
  
  Nature Material 4
  
  Pages: 934-941
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular PH-triggered drug release property : Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy2005
- Author(s)
  Bae Y, Nishiyama N, Koayama H, Kataoka K, et al.
- Journal Title
  
  Bioconjug.Chem. 16
  
  Pages: 122-130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005
- Author(s)
  Nishiyama, N., Kataoka, K.et al.
- Journal Title
  
  Nature Materials 4(12)
  
  Pages: 934-941
- Data Source
  KAKENHI-PROJECT-17016017
[Journal Article] Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles2005
- Author(s)
  Cabral H, Nishiyama N, Koyama H, Kataoka K, et al.
- Journal Title
  
  J. Control. Release 101
  
  Pages: 223-232
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Preparation of biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property, tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy2005
- Author(s)
  Bae, Y., Nishiyama, N., et al.
- Journal Title
  
  Bioconjugate Chemistry 16(1)
  
  Pages: 122-130
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Freeze-dried formulations for in vivo gene delivery of PEGylated polyplex micelles with disulfide crosslinked cores to the liver2005
- Author(s)
  K. Miyata, Y. Kakizawa, N. Nishiyama, Y. Yamasaki, T. Watanabe, M. Kohara, K. Kataoka
- Journal Title
  
  J. Control. Release 109(1-3)
  
  Pages: 15-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells2005
- Author(s)
  Oishi, M., Nishiyama, N., et al.
- Journal Title
  
  Journal of the American Chemical Society 127(6)
  
  Pages: 1624-1625
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats2005
- Author(s)
  H. Uchino, Y. Matsumura, T. Negishi, F. Koizumi, T. Hayashi, T. Honda, N. Nishiyama, K. Kataoka, S. Naito, T. Kakizoe
- Journal Title
  
  Br. J. Cancer 93(6)
  
  Pages: 678-687
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17200031
[Journal Article] Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression.2004
- Author(s)
  Miyata K, Koyama H, Nishiyama N, Kataoka, K et al.
- Journal Title
  
  Journal of American Chemical Society 126
  
  Pages: 2355-2361
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Polyion complex micelles of pDNA with acetal-poly(ethylene glycol)-poly(2-(dimethylamino)ethyl methacrylate) block copolymer as the gene carrier system : physicochemical properties of micelles relevant to gene transfection efficacy2004
- Author(s)
  Wakebayashi, D., Nishiyama, N., et al.
- Journal Title
  
  Biomacromolecules 5(6)
  
  Pages: 2128-2136
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Supramolecular nanocarrier of siRNA from PEG-based catiomer carrying diamine side chain with distinct pKa directed to enhance intracellular gene silencing2004
- Author(s)
  Itaka, K., Nishiyama, N., et al.
- Journal Title
  
  Journal of the American Chemical Society 126(42)
  
  Pages: 13612-13613
- Data Source
  KAKENHI-PROJECT-16680020
[Journal Article] Gelatin hydrogel microspheres enable pinpoint delivery of basic fibroblast growth factor for development of functional collateral vessels.2004
- Author(s)
  Hosaka A, Koyama H, Miyata T, Nishiyama N et al.
- Journal Title
  
  Circulation 110
  
  Pages: 3322-3328
- Data Source
  KAKENHI-PROJECT-15390373
[Journal Article] Effective transgene expression without toxicity by intraperitoneal administration of PEG-detachable polyplex micelles in mice with peritoneal dissemination
- Author(s)
  Kumagai M, Shimoda S, Wakabayashi R, Kunisawa Y, Ishii T, Osada K, Itaka K, Nishiyama N, Kataoka K, Nakano K
- Journal Title
  
  J Control Release
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390374
[Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles
- Author(s)
  Y. Vachutinsky, M. Oba, K. Miyata, S. Hiki, M.R. Kano, N. Nishiyama, H. Koyama, K. Miyazono, K. Kataoka
- Journal Title
  
  J. Control. Release (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016017
[Patent] 単一高分子からなる自己凝集型ミセル2023
- Inventor(s)
  西山伸宏、三浦裕、他7名
- Industrial Property Rights Holder
  西山伸宏、三浦裕、他7名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-124868
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22H00581
[Patent] グルタミントランスポーターと多価結合することができるリガンド, 及び当該リガンドを含む組成物2017
- Inventor(s)
  西山伸宏、武元宏泰、野本貴大、他7名
- Industrial Property Rights Holder
  東京工業大学, 大阪大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04635
[Patent] 温度応答性ポリマー及びそれを含む組成物2017
- Inventor(s)
  西山伸宏　他6名
- Industrial Property Rights Holder
  東京工業大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-211893
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K15104
[Patent] グルタミントランスポーターと多価結合することができるリガンド, 及び当該リガンドを含む組成物2016
- Inventor(s)
  西山伸宏, 武元宏泰, 野本貴大, 友田敬士郎, 松井誠他
- Industrial Property Rights Holder
  東京工業大学, 大阪大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-161774
- Filing Date
  2016-08-22
- Data Source
  KAKENHI-PROJECT-15H04635
[Patent] 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法2014
- Inventor(s)
  片岡一則, 安楽泰孝, 西山伸宏, 宮田完二郎, 石井武彦, 松本有, 福里優, 溝口明祐, 横田隆徳, 桑原宏哉, 仁科一隆, 水澤英洋
- Industrial Property Rights Holder
  国立大学法人東京大学、国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-096935
- Filing Date
  2014-05-08
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法2014
- Inventor(s)
  片岡一則、安楽泰孝、西山伸宏、宮田完二郎、石井武彦、松本有、溝口明祐、横田隆徳、桑原宏哉、仁科一隆、水澤英洋
- Industrial Property Rights Holder
  国立大学法人東京大学国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-11-21
- Acquisition Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法2013
- Inventor(s)
  片岡一則、安楽泰孝、西山伸宏、宮田完二郎、石井武彦、松本有、福里優、溝口明祐、横田隆徳、桑原宏哉、仁科一隆、水澤英洋
- Industrial Property Rights Holder
  国立大学法人東京大学、国立大学法人東京医科歯科大
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-22
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] 核酸デリバリー用ユニット構造型医薬組成物2013
- Inventor(s)
  片岡一則、宮田完二郎、西山伸宏、長田健介、渡邊秀美代、福島重人、茶谷洋行、武元宏泰、加藤泰己
- Industrial Property Rights Holder
  国立大学法人東京大学、ナノキャリア株式会社
- Filing Date
  2013-04-30
- Data Source
  KAKENHI-PROJECT-25000006
[Patent] TNF-a, CD40L及びGM-CSF併用遺伝子治療剤2011
- Inventor(s)
  中野賢二、片岡一則、西山伸宏
- Industrial Property Rights Holder
  九州大学、東京大学
- Filing Date
  2011-12-28
- Overseas
- Data Source
  KAKENHI-PROJECT-21390374
[Patent] TNF-α,CD40L及びGM-CSF併用遺伝子治療剤2011
- Inventor(s)
  中野賢二、片岡一則、西山伸宏
- Industrial Property Rights Holder
  九州大学、東京大学
- Industrial Property Number
  2010-294035
- Filing Date
  2011-12-28
- Overseas
- Data Source
  KAKENHI-PROJECT-21390374
[Patent] 高分子ミセル内包TNF-α遺伝子治療剤2010
- Inventor(s)
  中野賢二、片岡一則、西山伸宏
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2010-07-02
- Overseas
- Data Source
  KAKENHI-PROJECT-21390374
[Patent] 核酸送達用組成物及び担体組成物、それを用いた医薬組成物、並びに核酸送達方法2010
- Inventor(s)
  片岡一則,フレデリコピテラシルバ,ミンゼンジャン,西山伸宏,宮田完二郎,ヤンイー
- Industrial Property Rights Holder
  国立大学法人,東京大学
- Industrial Property Number
  2010-102880
- Filing Date
  2010-04-28
- Data Source
  KAKENHI-PROJECT-21659299
[Patent] TNF-α遺伝子治療剤2010
- Inventor(s)
  中野賢二、片岡一則、西山伸宏他
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2009-158282
- Filing Date
  2010-07-02
- Overseas
- Data Source
  KAKENHI-PROJECT-21390374
[Patent] Size Controlled Micelle of Plutinum Coordination Complex2009
- Inventor(s)
  西山伸宏, 片岡一則, 他2名
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2009-07-16
- Overseas
- Data Source
  KAKENHI-PROJECT-21659299
[Patent] カチオン性のポリ(アミノ酸)およびその使用2009
- Inventor(s)
  西山伸宏、他5名
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2009-031799
- Filing Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-19680026
[Patent] カチオン性のポリ(アミノ酸)およびその使用2009
- Inventor(s)
  西山伸宏, 片岡一則, 宮田完二郎, 石井武彦, 呉寿栄, キムヒュンジン
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Number
  2009-031799
- Filing Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-17016017
[Patent] Size Controlled Micelle of Plutinum Coordination Complex2009
- Inventor(s)
  西山伸宏、片岡一則, 他2名
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2009-07-16
- Overseas
- Data Source
  KAKENHI-PROJECT-19680026
[Patent] カチオン性のポリ(アミノ酸)およびその使用2009
- Inventor(s)
  西山伸宏, 片岡一則, 宮田完二郎, 石井武彦, 呉寿栄, キムヒュンジン
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Number
  2009-031799
- Filing Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-19680026
[Patent] ポリエチレングリコールの結合した核酸のコンジュゲートとリン酸カルシウムの有機-無機ハイブリッド型ナノ粒子2007
- Inventor(s)
  西山伸宏他4名
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2007-280803
- Filing Date
  2007-10-29
- Data Source
  KAKENHI-PROJECT-19680026
[Patent] TGF-βシグナル阻害剤と抗腫瘍剤の組み合わせ使用2006
- Inventor(s)
  西山伸宏, 他4名
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2006-02-01
- Data Source
  KAKENHI-PROJECT-17200031
[Patent] TGF-βシグナル阻害剤と抗腫瘍剤の組み合わせ使用2006
- Inventor(s)
  西山伸宏, 他4名
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2006-02-01
- Data Source
  KAKENHI-PROJECT-17016017
[Patent] tgf-βシグナル阻害剤と抗腫瘍剤の組み合せ使用2006
- Inventor(s)
  宮園浩平, 狩野光伸, べーユンスー, 西山伸宏, 片岡一則
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2006-08-30
- Data Source
  KAKENHI-PROJECT-17016017
[Patent] pH応答性高分子ミセルの調製に用いる新規ブロック共重合体及びその製造法の提供2005
- Inventor(s)
  西山伸宏, 他4名
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2005-035233
- Filing Date
  2005-04-22
- Data Source
  KAKENHI-PROJECT-16680020
[Presentation] 高分子コア-シェル設計に基づくバイオ医薬品送達システムの開発2024
- Author(s)
  西山伸宏
- Organizer
  CBI学会第454回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 高分子ナノテクノロジーを基盤とするバイオ医薬品送達システムの開発2024
- Author(s)
  西山伸宏
- Organizer
  湘南iPark Innovator’s Crosstalk ナノメディシン
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 精密合成ポリマー技術を基盤としたナノメディシンの研究開発2024
- Author(s)
  西山伸宏
- Organizer
  高分子学会　2023年度Webinar講演
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] バイオ医薬品のデリバリーのための高分子ミセル型ナノマシンの創製2024
- Author(s)
  西山伸宏
- Organizer
  日本化学会第104春季年会 CIPセッション
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] アデノ随伴ウイルス (AAV)の腫瘍選択性を向上させる環状ペプチドリガンド導入三元系複合体の開発2023
- Author(s)
  松平望, 本田雄士, 長尾周平, 喜納宏明, 野本貴大, 三浦裕, 西山伸宏
- Organizer
  第29回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 超分子複合体を基盤とした全身投与可能なCas9-sgRNP RNP送達システムの開発2023
- Author(s)
  本田雄士, 松尾拓海, 野本貴大, 西山伸宏
- Organizer
  第29回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 精密高分子合成を基盤とするスマートナノマシンの創製2023
- Author(s)
  西山伸宏
- Organizer
  高分子進化工学第一回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] ボロン酸エステルを基盤とした細胞内相転移による高分子-細胞間相互作用制御および薬物送達キャリアとしての応用2023
- Author(s)
  本田雄士、シャイクリザルエルムツタキン、西山伸宏、野本貴大
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 外部刺激に応答するナノマシン2023
- Author(s)
  西山伸宏
- Organizer
  第6回iCONM市民公開講座「ナノマシン研究の最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 高分子コア-シェル設計に基づくバイオ医薬品送達システムの開発2023
- Author(s)
  西山伸宏
- Organizer
  CBI学会第454回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] 高分子三元系複合体を基盤とした全身投与型 Cas9-sgRNP RNP 送達システムの開発2023
- Author(s)
  本田雄士、松尾拓海，野本貴大，刑部祐里子，西山伸宏
- Organizer
  日本ゲノム編集学会　第８回大会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] Core-Shell Design for Smart Polymeric Micelles2023
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  ChinaNanomedicine2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] PHPMA を基盤としたホウ素中性子捕捉療法用薬物送達システムの開発2023
- Author(s)
  登倉大貴, 小成田翔, 鈴木実, 本田雄士, 西山伸宏, 野本貴大
- Organizer
  第72回高分子討論会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] タンニン酸とフェニルボロン酸導入高分子から形成されるオボアルブミン内包三元系複合体の構築とがんワクチンアジュバントとしての応用2023
- Author(s)
  Anudari Batbayar, 大橋遼太郎, 本田雄士, 野本貴大, 三浦裕, 西山伸宏
- Organizer
  第45回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] ポリベタイン修飾脂質ナノ粒子を用いたpH変化をトリガーとする腫瘍選択的siRNA送達システムの開発2023
- Author(s)
  小林基晃、Ghasemizadeh Aria、豊田真広、Chintrakulchai Wanphiwat、Sung Yijung、Shen Xin、本田雄士、野本貴大、三浦裕、西山伸宏
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] タンニン酸とフェニルボロン酸導入高分子から形成されるオボアルブミン内包三元系複合体の構築とがんワクチンアジュバントとしての応用2023
- Author(s)
  Anudari Batbayar、Anudari Batbayar, 大橋遼太郎, 本田雄士, 野本貴大, 三浦裕, 西山伸宏
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 抗体耐性を中和するポリマーコーティングと組み合わせたアデノ随伴ウイルス(AAV)送達システムの開発2023
- Author(s)
  本田雄士、Yao Xiao、喜納宏明、西山伸宏
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] バイオ医薬品のデリバリーのための高分子ミセル型ナノマシンの創製2023
- Author(s)
  西山伸宏
- Organizer
  日本化学会第104春季年会 CIPセッション
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] 外部刺激に応答するナノマシン2023
- Author(s)
  西山伸宏
- Organizer
  第6回iCONM市民公開講座「ナノマシン研究の最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] ポリフェノールと自己会合型三元系複合体を形成するボロン酸導入高分子の構造検討と機械学習を用いた解析2023
- Author(s)
  本田雄士、臼倉幸一 , 野本貴大 , 西山伸宏
- Organizer
  第72回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 精密高分子合成を基盤とするスマートナノマシンの創製2023
- Author(s)
  西山伸宏
- Organizer
  茨城地区高分子学会若手の会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] cRGD 結合 PEG 修飾抗 PD-L1 抗体の開発と腫瘍標的性向上のための最適化2023
- Author(s)
  新田祥子, 持田祐希, 本田雄士, 西山伸宏
- Organizer
  第45回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 精密高分子設計に基づくスマート機能型ナノDDSの創製2023
- Author(s)
  西山伸宏
- Organizer
  第33回日本光線力学学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] Core-Shell Design for Smart Polymeric Micelles2023
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  ChinaNanomedicine2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] 高分子が拓く未来医療～スマートナノマシンの実現を目指して～2023
- Author(s)
  西山伸宏
- Organizer
  第5回東京理科大学物理学園賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-23H05451
[Presentation] 腫瘍標的機能を備えた環状ペプチド搭載アデノ随伴ウイルス(AAV)三元系複合体の開発2023
- Author(s)
  松平望、本田雄士、長尾周平、喜納宏明、野本貴大、三浦裕、西山伸宏
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 高分子が拓く未来医療スマートナノマシンの実現を目指して2023
- Author(s)
  西山伸宏
- Organizer
  第5回東京理科大学物理学園賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 精密高分子設計に基づくスマート機能型ナノDDSの創製2023
- Author(s)
  西山伸宏
- Organizer
  Laser Week in Tokyo 第33回日本光線力学学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 次世代スマートナノマシンの研究開発2023
- Author(s)
  西山伸宏
- Organizer
  装備庁講演
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 集束超音波と高分子複合体を組み合わせた脳選択的AAV送達システムの構築2022
- Author(s)
  本田雄士, 長尾周平, 喜納宏昭, 松平望, Liu Xueying, 野本貴大, Dirisala Anjaneyulu, 三浦裕, 片岡一則, 西山伸宏
- Organizer
  第44回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 精密合成ポリマー技術を基盤としたナノメディシンの研究開発2022
- Author(s)
  西山伸宏
- Organizer
  製薬協 DDSコンソーシアム
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 量子ビーム照射によって架橋したゼラチンハイドロゲルの合成とタンパク質薬剤の徐放2022
- Author(s)
  上野真夕, 大野哲史, 石田翔大, 松井誠, 杉山仁志, 永井一清, 大山智子, 田口光正, 西山伸宏, 三浦裕
- Organizer
  第38回DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] Design and Synthesis of Sub-10 nm Polymer-Drug conjugates for Drug Delivery Applications2022
- Author(s)
  Gao Shan, Ohno Satoshi, Ogata Keisuke, Ishida Shota, Nishiyama Nobuhiro, Miura Yutaka
- Organizer
  第71回高分子討論会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 精密高分子設計に基づくナノDDSの設計と光治療への応用2022
- Author(s)
  西山伸宏
- Organizer
  第43回日本レーザー医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 腫瘍細胞標的機能を備えた全身投与型アデノ随伴ウイルス(AAV)三元系複合体の開発2022
- Author(s)
  松平望, 本田雄士,　長尾周平,喜納宏昭,　野本貴大,　Liu Xueying, Dirisala Anjaneyulu,三浦裕, 片岡一則, 西山伸宏
- Organizer
  第44回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] Sequential self-assembly bio-building blocks based on polyphenol materials for efficient biomolecules delivery2022
- Author(s)
  Yuto Honda, Takahiro Nomoto, Nobuhiro Nishiyama
- Organizer
  第44回日本バイオマテリアル学会大会, 日韓バイオマテリアル若手交流AWARDセッション
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] Novel core-shell design for smart polymeric micelles2022
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  International Symposium on Advanced Biomaterials
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 高分子ミセルによる核酸・ペプチド・タンパク質医薬品の送達技術に関する研究2022
- Author(s)
  西山伸宏
- Organizer
  日本薬物動態学会第37回年会
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] ガンマ線架橋ゼラチンハイドロゲルの薬剤徐放型人工血管としての開発2022
- Author(s)
  上野真夕, 大野哲史, 石田翔大, 宮崎大輔, 本田雄士, 松井誠, 野本貴大, 遠藤貴士, 高山利夫, 大山智子, 田口光正, 西山伸宏, 三浦裕
- Organizer
  第70回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] Screening and structural analysis of boronic acid-conjugated polymers capable of stable ester formation with polyphenol structural molecules in in vivo2022
- Author(s)
  Yuto Honda, Ko-ichi Usukura, Takahiro Nomoto, Yutaka Miura, Nobuhiro Nishiyama
- Organizer
  第71回高分子討論会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] プラスミドDNAデリバリーを指向したpH変換型ポリ双性イオン導入ナノシステムの開発2022
- Author(s)
  Xin Shen, Dirisala Anjaneyulu, Yuto Honda, Takahiro Nomoto, Hiroyasu Takemoto, Yutaka Miura, Nobuhiro Nishiyama
- Organizer
  第38回DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 精密高分子設計を基盤とする中分子バイオ医薬品のDDS開発2022
- Author(s)
  西山伸宏
- Organizer
  第17回日本がん分子標的治療学会 TRワークショップ次世代がん創薬としての中分子領域薬の開発フロンティア（オンライン開催）
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 機能性高分子の分子設計を基盤とする革新的ナノメディシンの創製2022
- Author(s)
  西山伸宏
- Organizer
  ポリマーフロンティア21
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 高分子鉄キレート剤を用いた腫瘍免疫環境制御の検討2022
- Author(s)
  Guo Haochen, 野本貴大, 喜納宏昭, 石原純, 松井誠, Sung Yijung, 西山伸宏
- Organizer
  第38回DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 高分子の精密設計に基づくがん診断・治療用ナノマシンの創製2022
- Author(s)
  西山伸宏
- Organizer
  日本薬学会第142年会一般シンポジウムS29 元素の力で切り拓く新時代の創薬イノベーション~多元素化合物による革新的生物機能分子の創製 (オンライン開催)
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] バイオ医薬品送達システムを指向した高分子ミセルのコア-シェル設計2022
- Author(s)
  西山伸宏
- Organizer
  超細胞・DDS研究開発部門シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] 量子ビーム架橋ゼラチンハイドロゲルの人工血管被覆材への応用2022
- Author(s)
  上野真夕, 大野哲史, 石田翔大, 本田雄士, 松井誠, 野本貴大, 杉山仁志, 永井一清, 遠藤貴士, 高山利夫, 大山智子, 田口光正, 西山伸宏, 三浦裕
- Organizer
  第71回高分子討論会
- Data Source
  KAKENHI-PROJECT-22H00581
[Presentation] タンニン酸とフェニルボロン酸導入高分子から成る自己会合型ナノリアクターの構築および酵素プロドラッグ療法への応用2021
- Author(s)
  本田雄士、野本貴大、松井誠、三浦裕、西山伸宏
- Organizer
  第37回日本DDS学会学術集会(幕張メッセ国際会議場/オンライン)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] アデノ随伴ウイルス(AAV)ベクターの中和抗体および副作用を克服するAAV/タンニン酸/ボロン酸導入高分子三元系複合体の構築2021
- Author(s)
  長尾周平、本田雄士、喜納宏昭、野本貴大、Liu Xueying、Dirisala Anjaneyulu、松井誠、三浦裕、片岡一則、西山伸宏
- Organizer
  第37回日本DDS学会学術集会(幕張メッセ国際会議場/オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 高分子鉄キレート剤を用いた腫瘍内鉄イオン制御とそのアスコルビン酸の抗腫瘍効果への影響に関する検討2021
- Author(s)
  Guo Haochen、野本貴大、松井誠、河本花奈、Muttaqien Sjaikhurrizal El、三浦裕、西山伸宏
- Organizer
  第37回日本DDS学会学術集会(幕張メッセ国際会議場/オンライン)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Poly(vinyl alcohol)によるD-4-boronophenylalanineの治療効果向上2021
- Author(s)
  小成田翔、野本貴大、金盛開人、鈴木実、松井誠、三浦裕、西山伸宏
- Organizer
  第17回日本中性子捕捉療法学会学術大会(KKRホテル熱海/オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] タンニン酸とフェニルボロン酸導入高分子で構築された自己会合型Cas9 RNP送達システムの開発2021
- Author(s)
  松尾拓海、本田雄士、野本貴大、松井誠、三浦裕、西山伸宏
- Organizer
  第70回高分子討論会（オンライン開催）
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Poly(vinyl alcohol)と D-4-boronophenylalanine から構成される薬物送達システムによるホウ素中性子捕捉療法の検討2021
- Author(s)
  小成田翔、野本貴大、金盛開人、鈴木実、松井誠、三浦裕、西山伸宏
- Organizer
  第70回高分子学会年次大会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 高分子鉄キレート剤を利用した腫瘍免疫逃避環境の克服2021
- Author(s)
  Guo Haochen、野本貴大、松井誠、 Voon Yan Ming、ソンイーロン、三浦裕、西山伸宏
- Organizer
  第70回高分子討論会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 官能基が異なるボロン酸導入高分子とタンニン酸で構成されたタンパク質三元系複合体の安定性評価2021
- Author(s)
  臼倉幸一、本田雄士、野本貴大、松井誠、三浦裕、西山伸宏
- Organizer
  第70回高分子討論会（オンライン開催）
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] タンニン酸とフェニルボロン酸導入高分子の自己会合によって形成されたナノリアクターの酵素プロドラッグ療法への応用2021
- Author(s)
  本田雄士、野本貴大、松井誠、三浦裕、西山伸宏
- Organizer
  第31回バイオ・高分子シンポジウム（オンライン開催）
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] ポリビニルアルコールを利用したボロノフェニルアラニンの中性子捕捉療法における治療効果向上2021
- Author(s)
  野本貴大、小成田翔、鈴木実、松井誠、西山伸宏
- Organizer
  第37回日本DDS学会学術集会(幕張メッセ国際会議場/オンライン)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] タンニン酸とフェニルボロン酸修飾高分子からなるCRISPR/Casタンパク質デリバリーシステムの開発2021
- Author(s)
  松尾拓海、本田雄士、野本貴大、松井誠、三浦裕、西山伸宏
- Organizer
  第37回日本DDS学会学術集会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] タンニン酸とフェニルボロン酸導入高分子で構成されるオボアルブミン封入三元系複合体の構築とがん免疫療法への応用2021
- Author(s)
  大橋遼太郎、本田雄士、松井誠、野本貴大、三浦裕、西山伸宏
- Organizer
  第37回日本DDS学会学術集会(幕張メッセ国際会議場/オンライン)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] ボロン酸エステルを介したスタチン内包高分子型ミセルの構築および薬理効果2021
- Author(s)
  本田雄士、福原菜摘, 浮田菜央, 松井誠, 大野哲史, 野本貴大, 西山伸宏, 保科克行, 三浦裕
- Organizer
  第37回日本DDS学会学術集会(幕張メッセ国際会議場/オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Novel core-shell design for smart polymeric micelles2021
- Author(s)
  西山伸宏
- Organizer
  Materials Research Meeting 2021 (MRM2021)（Pacifico Yokohama）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 効率的なタンパク質送達を指向したタンニン酸とフェニルボロン酸導入高分子で構成されたタンパク質内包三元系複合体の構築2021
- Author(s)
  本田雄士、野本貴大、松井誠、三浦裕、西山伸宏
- Organizer
  第70回高分子討論会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Construction of sequential self-assembled protein ternary complex utilizing boronic acid conjugated-polymer and tannic acid for protein delivery2021
- Author(s)
  Yuto Honda、Takahiro Nomoto, Makoto Matsui, Yutaka Miura, Nobuhiro Nishiyama
- Organizer
  ACS Fall 2021 (オンライン開催)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 環状アセタール構造を介したゲムシタビンのポリアミノ酸への導入と薬効増大および副作用低減2020
- Author(s)
  武元宏泰, 野本貴大, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第69回高分子学会年次大会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 腫瘍内pH応答性の獲得を目指した高分子ベタイン内の両イオン性基の種類・間隔の検討2020
- Author(s)
  豊田真広, 武元宏泰, 野本貴大, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第69回高分子討論会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 中性子捕捉療法におけるボロノフェニルアラニンの治療効果を向上する機能性高分子の開発2020
- Author(s)
  野本貴大, 井上透矢, Yao Ying, 鈴木実, 金盛開人, 小成田翔, 武元宏泰, 松井誠, 西山伸宏
- Organizer
  第69回高分子討論会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 高分子修飾によるsiRNA周囲の空間支配と薬理機構制御2020
- Author(s)
  武元宏泰, 野本貴大, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第69回高分子討論会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 高分子の精密設計に基づくホウ素薬剤送達システムの開発2020
- Author(s)
  西山伸宏
- Organizer
  令和2 年度京都大学複合原子力科学研究所専門研究会「京都大学複合原子力科学研究所におけるBNCT 研究の多様化・高度化に関する研究会」（オンライン開催）
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] pH反応性ポリマーとナノ粒子2020
- Author(s)
  西山伸宏
- Organizer
  第5回 MRIアライアンス・シンポジウム（オンライン開催）
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 環状アセタール構造に基づくゲムシタビン担持型高分子の開発とその機能評価および副作用低減2020
- Author(s)
  武元宏泰, 稲葉高徳, 野本貴大, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第36回日本DDS学会学術大会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Development of a versatile drug delivery system using tannic acid and boronic acid-conjugated polymer2020
- Author(s)
  I Dewa Agung Panji Dwipayana, Yuto Honda, Takahiro Nomoto, Hiroyasu Takemoto, Makoto Matsui, Yutaka Miura, Nobuhiro Nishiyama
- Organizer
  第69回高分子討論会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 骨折治癒促進効果を有するDDS 医薬品の創製2020
- Author(s)
  松井誠, 海原悠可, 武元宏泰, 野本貴大, 三浦裕, 西山伸宏
- Organizer
  第36回日本DDS学会学術大会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 高分子ベタイン内のイオン性基の種類・間隔の制御と腫瘍内pH応答性への展開2020
- Author(s)
  豊田真広, 武元宏泰, 野本貴大, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第69回高分子学会年次大会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] ASO-分岐PEG結合体を内包する小分子キャリアの開発および機能評価2020
- Author(s)
  Sun Yudi, 武元宏泰, 野本貴大, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第69回高分子討論会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 高分子の精密設計に基づくナノDDSの開発2020
- Author(s)
  西山伸宏
- Organizer
  お茶の水がん学アカデミア第 162 回集会（オンライン開催）
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Iron chelation cancer therapy using functional polymers targeting tumors2020
- Author(s)
  Kana Komoto, Takahiro Nomoto, Hiroyasu Takemoto, Matsui Makoto, Yutaka Miura, Nobuhiro Nishiyama
- Organizer
  International Symposium on Biomedical Materials for Drug/Gene Delivery, Alumni House, University of Utah, UT, USA
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 高濃度ビタミンC療法の治療効果向上を指向した高分子鉄キレート剤2020
- Author(s)
  Guo Haochen,野本貴大, 河本花奈, ムツタキンシャイクリザルエル, ソンショウギョウ, 武元宏泰, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第69回高分子討論会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 機能性ポリマーの精密設計に基づくナノメディシンの開発2020
- Author(s)
  西山伸宏
- Organizer
  第15回理研「バイオものづくり」シンポジウム（オンライン開催）
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Poly(vinyl alcohol) for enhancing therapeutic effects of p-boronophenylalanine in neutron capture therapy2020
- Author(s)
  Takahiro Nomoto, Yukiya Inoue, Ying Yao, Minoru Suzuki, Kaito Kanamori, Hiroyasu Takemoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  International Symposium on Biomedical Materials for Drug/Gene Delivery, Alumni House, University of Utah, UT, USA
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Shell and core design of polymeric micelles for delivery of biopharmaceuticals2020
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  A3 Foresight & 5 Star Alliance Joint Workyoushop (Online Meeting)
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Effect of polymeric iron-chelators on high-dose vitamin C therapy2020
- Author(s)
  Guo Haochen, 野本貴大, 河本花奈,ムツタキンシャイクリザルエル, ソンショウギョウ, 武元宏泰, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第36回日本DDS学会学術大会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] がん鉄キレート療法のための効率的な除鉄を実現する機能性高分子の開発2020
- Author(s)
  河本花奈, 野本貴大, Sjaikhurrizal El Muttaqien, 武元宏泰, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第69回高分子討論会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Development of intracellular pH- responsive protein delivery system utilizing boronic acid-conjugated polymer and tannic acid2020
- Author(s)
  Yuto Honda, Takahiro Nomoto, Makoto Matsui, Hiroyasu Takemoto, Yuka Kaihara, Yutaka Miura, Nobuhiro Nishiyama
- Organizer
  International Symposium on Biomedical Materials for Drug/Gene Delivery, Alumni House, University of Utah, UT, USA
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] ASO-PEG結合体の開発と単分子ASO内包キャリアへの展開2020
- Author(s)
  SUN Yudi, 武元宏泰, 野本貴大, 松井誠, 三浦裕, 西山伸宏
- Organizer
  第36回日本DDS学会学術大会(オンライン開催)
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 精密高分子設計に基づくDDSとPDT応用2019
- Author(s)
  西山伸宏
- Organizer
  PhotoDynamic Medicine 2019 (PDM2019)、ホテルグランドヒル市ヶ谷、東京
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 機能性高分子の精密設計に基づく医療ナノマシンの創製2019
- Author(s)
  西山伸宏
- Organizer
  ニューモダリティと有機合成化学”研究部会, 第2回勉強会化学会館, 東京
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 温度応答性高分子-siRNA結合体とのポリイオンコンプレックス形成と外部刺激によるsiRNA の薬効制御2019
- Author(s)
  小野寺彩、武元宏泰、野本貴大、友田敬士郎、松井誠、西山伸宏
- Organizer
  第35回日本DDS学会学術集会、パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 腫瘍内低pH環境に応答して親水-疎水相転移挙動を示す高分子コンジュゲート型光増感剤2019
- Author(s)
  野本貴大、Sjaikhurrizal El Muttaqien、武元宏泰、松井誠、西山伸宏
- Organizer
  PhotoDynamic Medicine 2019 (PDM2019)、ホテルグランドヒル市ヶ谷、東京
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 腫瘍内pH応答性高分子ベタインの設計と被覆ナノ粒子への展開2019
- Author(s)
  武元宏泰、アワードアジズ、ラネーアブドゥルハカム、野本貴大、松井誠、三浦裕、西山伸宏
- Organizer
  第68回高分子討論会、福井大学文京キャンパス、福井
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] がん細胞の高密度グルタミントランスポーターを標的として選択的な相互作用を示す機能性高分子の開発2019
- Author(s)
  本田雄士、山田直生、武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第68回高分子学会年次大会、大阪府立国際会議場、大阪
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] ポリイオンコンプレックスを利用した温度応答性高分子-siRNA結合体の細胞内導入と外部刺激によるsiRNAの生物活性制御2019
- Author(s)
  小野寺彩、武元宏泰、野本貴大、友田敬士郎、松井誠、西山伸宏
- Organizer
  第68回高分子学会年次大会、大阪府立国際会議場、大阪
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 薬物送達技術を応用した新規骨折治療法の開発2019
- Author(s)
  松井誠、海原悠可、武元宏泰、野本貴大、西山伸宏
- Organizer
  第35回日本DDS学会学術集会、パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 生体適合性高分子とボロノフェニルアラニンから構成される中性子捕捉療法用代謝制御型ホウ素送達システム2019
- Author(s)
  野本貴大、井上透矢、Yao Ying、金盛開人、鈴木実、武元宏泰、松井誠、西山伸宏
- Organizer
  第41回日本バイオマテリアル学会大会、つくば国際会議場、つくば
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 生体適合性高分子とp-boronophenylalanineから構成されるホウ素送達システムの開発と構成高分子の物性が体内動態と治療効果に与える影響に関する考察2019
- Author(s)
  野本貴大、井上透矢、Yao Ying、金盛開人、鈴木実、武元宏泰、松井誠、友田敬士郎、西山伸宏
- Organizer
  第16回日本中性子捕捉療法学会、京都大学宇治キャンパス、京都
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 環状アセタール構造に基づくゲムシタビンの高分子修飾と制がん効果増大及び副作用低減2019
- Author(s)
  武元宏泰、稲葉高徳、野本貴大、松井誠、三浦裕、西山伸宏
- Organizer
  第41回日本バイオマテリアル学会大会、つくば国際会議場、つくば
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Design of functional polymers for smart nanomedicine2019
- Author(s)
  Noburhiro Nishiyama
- Organizer
  Liposome Research Days (LRD2019) in Sapporo, Hokkaido University, Sapporo, Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Photosensitizer delivery to tumor cells and tumor-associated vasculature using functional polymers2019
- Author(s)
  Takahiro Nomoto, Xuebo Dou, Hiroyasu Takemoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  7th International ALA and Prophyrin Symposium (IAPS7)、北海道大学、札幌
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 温度応答性高分子-siRNA結合体の合成と外部刺激によるsiRNAの生物活性制御2019
- Author(s)
  小野寺彩、武元宏泰、野本貴大、松井誠、三浦裕、西山伸宏
- Organizer
  第68回高分子討論会、福井大学文京キャンパス、福井
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 腫瘍内pH応答性高分子ベタイン内のイオン性基間距離の検討2019
- Author(s)
  豊田真広、武元宏泰、野本貴大、松井誠、西山伸宏
- Organizer
  第68回高分子学会年次大会、大阪府立国際会議場、大阪
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] ボロン酸導入高分子とタンニン酸を用いた細胞内環境応答タンパク質送達システムの構築2019
- Author(s)
  本田雄士、野本貴大、松井誠、武元宏泰、海原悠可、三浦裕、西山伸宏
- Organizer
  第41回日本バイオマテリアル学会大会、つくば国際会議場、つくば
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 腫瘍 pH 応答性高分子ベタインの開発とナノ粒子のがん送達への展開2019
- Author(s)
  武元宏泰、アワードアジズ、野本貴大、松井誠、西山伸宏
- Organizer
  第35回日本DDS学会学術集会、パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 糖修飾高分子とホウ素薬物から構成される薬物送達システムの開発2019
- Author(s)
  金盛開人、野本貴大、鈴木実、武元宏泰、松井誠、西山伸宏
- Organizer
  第68回高分子学会年次大会、大阪府立国際会議場、大阪
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Metabolism-controlled boron delivery systems composed of biocompatible polymers and boronophenylalanine for neutron capture therapy2019
- Author(s)
  Takahiro Nomoto, Yukiya Inoue, Ying Yao, Minoru Suzuki, Kaito Kanamori, Hiroyasu Takemoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  he ACS Spring 2019 National Meeting, Orange County Convention Center, FL, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] がん治療のための効率的な生体内の除鉄を実現する機能性高分子の開発2019
- Author(s)
  河本花奈、野本貴大、武元宏泰、松井誠、三浦裕、西山伸宏
- Organizer
  第41回日本バイオマテリアル学会大会、つくば国際会議場、つくば
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] ボロン酸エステルを利用したホウ素薬物送達キャリアの開発2019
- Author(s)
  金盛開人、野本貴大、鈴木実、武元宏泰、松井誠、西山伸宏
- Organizer
  第35回日本DDS学会学術集会、パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] がん細胞の高密度グルタミントランスポーターと選択的な相互作用を示す機能性高分子の開発2019
- Author(s)
  本田雄士、山田直生、武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第68回高分子討論会、福井大学文京キャンパス、福井
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] がん治療を指向した生体内鉄イオンをキレートする機能性高分子の開発2019
- Author(s)
  河本花奈、野本貴大、武元宏泰、松井誠、西山伸宏
- Organizer
  第35回日本DDS学会学術集会、パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Development of Smart Nanodiagnostics for Targeted Cancer Therapy2018
- Author(s)
  西山伸宏
- Organizer
  第2回MRIアライアンス国際シンポジウム2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 機能性ポリマーの精密設計に基づくスマート機能型ナノメディシンの創製2018
- Author(s)
  西山伸宏
- Organizer
  第56回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 機能性ポリマーによるナノDDS設計：高分子ミセルからナノマシンへ2018
- Author(s)
  西山伸宏
- Organizer
  第34回日本DDS学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 機能性高分子の設計に基づくがん診断・治療システムの開発2018
- Author(s)
  西山伸宏
- Organizer
  第35回医用高分子研究会講座
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Ethylenediamine-based betaine structure switches the neutral net charge of polyzwitterion into cationic at tumorous pH toward effective tumor accumulation of the coated nanomaterials2018
- Author(s)
  Hiroyasu Takemoto, Abduhl Hackam Ranneh, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  256th ACS National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Tumor cell-targeting glutamine-derived polymer that can interact with high density glutamine transporter based on aberrant glutamine metabolism2018
- Author(s)
  本田雄士, 山田直生, 武元宏泰, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 精密合成高分子材料を基盤するがん診断・治療ナノマシンの創製2018
- Author(s)
  西山伸宏
- Organizer
  第45回高分子同友会総合講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 精密合成ポリビニルアルコールによるボロノフェニルアラニンの治療効果向上2018
- Author(s)
  野本貴大, 井上透矢, Yao Ying, 鈴木実, 金盛開人, 武元宏泰, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第15回日本中性子捕捉療法学会学術大会
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] グルタミン代謝が亢進したがん細胞の高密度グルタミントランスポーターを認識してアフィニティを示す機能性高分子2018
- Author(s)
  本田雄士, 山田直生, 武元宏泰, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第67回高分子討論会
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Development of Smart Nanodiagnostics for Targeted Cancer Therapy2018
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  第2回MRIアライアンス国際シンポジウム2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Novel design of pH-responsive polymer for targeting acidic microenvironment of tumor2018
- Author(s)
  Sjaikhurrizal El Muttaqien, Takahiro Nomoto, Hiroyasu Takemoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  256th ACS National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 腫瘍内環境を認識する高分子べタインの開発とナノ粒子の効率的な腫瘍集積への展開2018
- Author(s)
  武元宏泰, Ranneh Abdul-Hackam, 野本貴大, 松井誠, 友田敬士郎, 持田祐希, 内藤瑞, 西山伸宏
- Organizer
  第67回高分子年次大会
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Metabolism-controlled boron delivery systems composed of p-boronophenylalanine and poly(vinyl alcohol)2018
- Author(s)
  Takahiro Nomoto, Yukiya Inoue, Ying Yao, Minoru Suzuki, Hiroyasu Takemoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  18th International Congress on Neutron Capture Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 機能性高分子の設計に基づくがん診断・治療システムの開発2018
- Author(s)
  西山伸宏
- Organizer
  第35回医用高分子研究会講座
- Invited
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 精密合成高分子材料を基盤するがん診断・治療ナノマシンの創製2018
- Author(s)
  西山伸宏
- Organizer
  第45回高分子同友会総合講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 機能性ポリマーの精密設計に基づくスマート機能型ナノメディシンの創製2018
- Author(s)
  西山伸宏
- Organizer
  第56回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Ethylenediamine-based polyzwitterion that becomes cationic at tumorous pH for effective tumor accumulation of the coated nanomaterials2018
- Author(s)
  Hiroyasu Takemoto, Abdul-Hackam Ranneh, Takahiro Nomoto, Makoto Matsui, Nobuhiro Nishiyama
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Smart nanomedicines based on the design of functional polymer2018
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  International Conference on Emerging Healthcare Materials 2018 (ICEHM2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Enhanced tumor-targeted delivery of p-boronophenylalanine using fructose-functionalized polymers for boron neutron capture therapy2018
- Author(s)
  Ying Yao, Takahiro Nomoto, Yukiya Inoue, Minoru Suzuki, Makoto Matsui, Hiroyasu Takemoto, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  18th International Congress on Neutron Capture Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Development of Smart Nanodiagnostics for Targeted Cancer Therapy2018
- Author(s)
  西山伸宏
- Organizer
  第2回MRIアライアンス国際シンポジウム2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of gemcitabine-conjugated poly(amino acid) and its evaluation using pancreatic tumor model2018
- Author(s)
  劉暁夢, 武元宏泰, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第67回高分子討論会
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 機能性高分子の精密設計に基づくナノメディシンの創製2018
- Author(s)
  西山伸宏
- Organizer
  日本接着学会東北支部講演会2018
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 機能性高分子の設計に基づくがん診断・治療システムの開発2018
- Author(s)
  西山伸宏
- Organizer
  第35回医用高分子研究会講座
- Invited
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Smart nanomedicines based on the design of functional polymer2018
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  International Conference on Emerging Healthcare Materials 2018 (ICEHM2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] IRDye 700DXの腫瘍内分布を制御する環状RGD担持高分子コンジュゲートによる光線力学効果の検討2018
- Author(s)
  野本貴大, Dou Xuebo, 武元宏泰, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Development of poly(amino acid)-based carrier that loads gemcitabine via reversible linkage and its evaluation using pancreatic cancer model2018
- Author(s)
  劉暁夢, 武元宏泰, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 機能性ポリマーの精密設計に基づくスマート機能型ナノメディシンの創製2018
- Author(s)
  西山伸宏
- Organizer
  第56回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Development of Smart Nanodiagnostics for Targeted Cancer Therapy2018
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  第2回MRIアライアンス国際シンポジウム2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] Smart nanomedicines based on the design of functional polymer2018
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  International Conference on Emerging Healthcare Materials 2018 (ICEHM2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Metabolism-controlled boron delivery systems composed of boronophenylalanine and functional polymers for neutron capture therapy2018
- Author(s)
  Takahiro Nomoto, Yukiya Inoue, Ying Yao, Minoru Suzuki, Kaito Kanamori, Hiroyasu Takemoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  The 12th SPSJ International Polymer Conference (IPC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 精密合成高分子材料を基盤するがん診断・治療ナノマシンの創製2018
- Author(s)
  西山伸宏
- Organizer
  第45回高分子同友会総合講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] Tumor-targeted delivery of BPA using functional polymers for boron neutron capture therapy2018
- Author(s)
  Yao Ying, 野本貴大, 井上透矢, 鈴木実, 松井誠, 武元宏泰, 友田敬士郎, 西山伸宏
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H04163
[Presentation] 機能性ポリマーによるナノDDS設計：高分子ミセルからナノマシンへ2018
- Author(s)
  西山伸宏
- Organizer
  第34回日本DDS学会学術総会
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 機能性ポリマーによるナノDDS設計：高分子ミセルからナノマシンへ2018
- Author(s)
  西山伸宏
- Organizer
  第34回日本DDS学会学術総会
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 2-Nitrobenzenesulfonamide group as a chemical linker with highly selective cleavability in response to intracellular redox system for a construction of siRNA-polymer conjugate2017
- Author(s)
  Hiroyasu Takemoto, Huang Chih-Hao, Takahiro Nomoto, Keishiro Tomoda, Makoto Matsui, Nobuhiro Nishiyama
- Organizer
  253rd American Chemical Society National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] スマート機能型DDSのための機能性高分子設計2017
- Author(s)
  西山伸宏
- Organizer
  高分子学会関東支部バイオと科学の融合領域
- Invited
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 糖骨格を有する制がん剤のポリアミノ酸への可逆的担持と薬効向上及び消化器毒性低減2017
- Author(s)
  武元宏泰、稲葉高徳、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] Development of polymer-based nanodevices for innovative medicine2017
- Author(s)
  N. Nishiyama
- Organizer
  Snowbird Symposium for Dr. Kopecek
- Place of Presentation
  Snowbird, Utah, U.S.A
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Design of functional polymers for smart nanomedicine2017
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  5th International Symposium on Smart Biomaterials
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 機能性高分子を利用した核酸医薬送達システムの開発2017
- Author(s)
  西山伸宏
- Organizer
  創薬薬理フォーラム第25回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Development of smart nanomachines for cancer imaging and minimally invasive treatment2017
- Author(s)
  N. Nishiyama
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki City
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] がん代謝に着想した表層にグルタミンを有する高分子ミセル型薬物送達システムの開発2017
- Author(s)
  真貝太規、山田直生, 武元宏泰, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] がん選択的に相互作用するグルタミン担持高分子の創製と機能評価2017
- Author(s)
  山田直生, 本田雄士，武元宏泰，野本貴大，松井誠，友田敬士郎，西山伸宏
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters2017
- Author(s)
  Naoki Yamada, Yuto Honda, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyamam
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Design of functional polymers for smart nanomedicine2017
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  5th International Symposium on Smart Biomaterials
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 2-Nitrobenzenesulfonamide group that allows highly selective cleavage in intracellular redox system and the application for a construction of siRNA-polymer conjugate2017
- Author(s)
  Hiroyasu Takemoto, Takahiro Nomoto, Keishiro Tomoda, Makoto Matsui, Nobuhiro Nishiyama
- Organizer
  14th US-JAPAN Symposium on Drug Delivery Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Design of functional polymers for cancer diagnosis and therapy2017
- Author(s)
  西山伸宏
- Organizer
  化学系学協会東北大会高分子コロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Design of functional polymers for smart nanomedicine2017
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  5th International Symposium on Smart Biomaterials
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] Glutamine-functionalized polymer for tumor-selective high affinity by sensing dense glutamine transporters associated with aberrant metabolism2017
- Author(s)
  Naoki Yamada, Naoki Yamada, Yuto Honda, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  14th US-JAPAN Symposium on Drug Delivery Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 機能性高分子を利用した核酸医薬送達システムの開発2017
- Author(s)
  西山伸宏
- Organizer
  創薬薬理フォーラム第25回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters2017
- Author(s)
  Naoki Yamada, Yuto Honda, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyamam
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Development of smart polymers and nanodevices for innovative medicine2017
- Author(s)
  N. Nishiyama
- Organizer
  International Symposium on Materials for Chemistry and Engineering (IMCE2017)
- Place of Presentation
  hikushi Hall (C-CUBE), Kyushu University, Fukuok
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 光増感剤結合型高分子における多岐環状ＲＧＤペプチドの腫瘍集積性と腫瘍内分布への効果の検討2017
- Author(s)
  Dou Xuebo、野本貴大、武元宏泰、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] がん特異的代謝に着想した外殻にグルタミンを有する高分子ミセルの開発2017
- Author(s)
  真貝太規、山田直生、武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 2-Nitrobenzenesulfonamide group as a chemical linker with highly selective cleavability in response to intracellular redox system for a construction of siRNA-polymer conjugate2017
- Author(s)
  Hiroyasu Takemoto, Huang Chih-Hao, Takahiro Nomoto, Keishiro Tomoda, Makoto Matsui, Nobuhiro Nishiyama
- Organizer
  253rd American Chemical Society National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] スマート機能型DDSのための機能性高分子設計2017
- Author(s)
  西山伸宏
- Organizer
  高分子学会関東支部バイオと科学の融合領域
- Invited
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism2017
- Author(s)
  Yuto Honda, Naoki Yamada, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  253rd American Chemical Society National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 腫瘍指向性ステルス高分子の開発とDDS への応用-ベタイン構造内アニオン性基の影響-2017
- Author(s)
  左久間隼矢、Abdul-Hackam RANNEH, 武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Design of functional polymers for cancer diagnosis and therapy2017
- Author(s)
  西山伸宏
- Organizer
  化学系学協会東北大会高分子コロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism2017
- Author(s)
  Yuto Honda, Naoki Yamada, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  253rd American Chemical Society National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 機能性高分子を利用した核酸医薬送達システムの開発2017
- Author(s)
  西山伸宏
- Organizer
  創薬薬理フォーラム第25回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 革新的オリゴ核酸送達システムの実現に向けた材料設計2017
- Author(s)
  西山伸宏
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 光増感剤結合型高分子における多岐環状ＲＧＤペプチドの腫瘍集積性と腫瘍内分布への効果の検討2017
- Author(s)
  Dou Xuebo、野本貴大、武元宏泰、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 2-Nitrobenzenesulfonamide group as a redox-sensitive linker for a construction of polymer-siRNA conjugate system2017
- Author(s)
  Hiroyasu Takemoto, Chih Hao Huang, Takahiro Nomoto, Keishiro Tomoda, Makoto Matsui, Nobuhiro Nishiyama
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] がん代謝に着想した表層にグルタミンを有する高分子ミセル型薬物送達システムの開発2017
- Author(s)
  真貝太規、山田直生, 武元宏泰, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] がん選択的に相互作用するグルタミン担持高分子の創製と機能評価,2017
- Author(s)
  山田直生, 本田雄士，武元宏泰，野本貴大，松井誠，友田敬士郎，西山伸宏
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 2-Nitrobenzenesulfonamide group that responds to intracellular redox potential with enhanced photostability for a construction of polymer-siRNA conjugate system2017
- Author(s)
  Hiroyasu Takemoto, Huang Chih-Hao, Takahiro Nomoto, Keishiro Tomoda, Makoto Matsui, Nobuhiro Nishiyama
- Organizer
  The 34th International Conference of Photopolymer Science and Technology (ICPST-34)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] がん特異的代謝に着想した外殻にグルタミンを有する高分子ミセルの開発2017
- Author(s)
  真貝太規、山田直生、武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] Development of smart polymers and nanodevices for innovative medicine2017
- Author(s)
  N. Nishiyama
- Organizer
  International Symposium on Materials for Chemistry and Engineering (IMCE2017)
- Place of Presentation
  Chikushi Hall (C-CUBE), Kyushu University, Fukuoka
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] がん選択的に相互作用するグルタミン担持高分子の創製と機能評価2017
- Author(s)
  山田直生, 本田雄士，武元宏泰，野本貴大，松井誠，友田敬士郎，西山伸宏
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] スマート機能型DDSのための機能性高分子設計2017
- Author(s)
  西山伸宏
- Organizer
  高分子学会関東支部バイオと科学の融合領域
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 機能性高分子を利用した核酸医薬送達システムの開発2017
- Author(s)
  西山伸宏
- Organizer
  創薬薬理フォーラム第25回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 革新的オリゴ核酸送達システムの実現に向けた材料設計2017
- Author(s)
  西山伸宏
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] ゲムシタビンのポリアミノ酸への可逆的担持に基づく消化器毒性低減及び制がん効果向上2017
- Author(s)
  武元宏泰, 稲葉高徳, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 腫瘍内pHに応答する双性イオン型ポリマーの設計とDDS応用-ベタイン内アニオン性基の影響-2017
- Author(s)
  左久間隼矢、Abdul-Hackam RANNEH, 武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Development of smart polymers and nanodevices for innovative medicine2017
- Author(s)
  N. Nishiyama
- Organizer
  International Symposium on Materials for Chemistry and Engineering (IMCE2017)
- Place of Presentation
  Chikushi Hall (C-CUBE), Kyushu University, Fukuoka
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 腫瘍内pHに応答する双性イオン型ポリマーの設計とDDS応用-ベタイン内アニオン性基の影響-2017
- Author(s)
  左久間隼矢、Abdul-Hackam RANNEH, 武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 2-Nitrobenzenesulfonamide group that allows highly selective cleavage in intracellular redox system and the application for a construction of siRNA-polymer conjugate2017
- Author(s)
  Hiroyasu Takemoto, Takahiro Nomoto, Keishiro Tomoda, Makoto Matsui, Nobuhiro Nishiyama
- Organizer
  14th US-JAPAN Symposium on Drug Delivery Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 腫瘍指向性ステルス高分子の開発とDDS への応用-ベタイン構造内アニオン性基の影響-2017
- Author(s)
  左久間隼矢、Abdul-Hackam RANNEH, 武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Development of polymer-based nanodevices for innovative medicine2017
- Author(s)
  N. Nishiyama
- Organizer
  Snowbird Symposium for Dr. Kopecek
- Place of Presentation
  Snowbird, Utah, U.S.A.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] ナノ材料を基盤とするスマート診断・治療システムの開発2017
- Author(s)
  西山伸宏
- Organizer
  ナレッジキャピタル超学校
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 2-Nitrobenzenesulfonamide group as a redox-sensitive linker for a construction of polymer-siRNA conjugate system2017
- Author(s)
  Hiroyasu Takemoto, Chih Hao Huang, Takahiro Nomoto, Keishiro Tomoda, Makoto Matsui, Nobuhiro Nishiyama
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 腫瘍内pHに応答する双性イオン型ポリマーの設計とDDS応用-ベタイン内アニオン性基の影響-2017
- Author(s)
  左久間隼矢、Abdul-Hackam RANNEH, 武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Glutamine-functionalized polymer for tumor-selective high affinity by sensing dense glutamine transporters associated with aberrant metabolism2017
- Author(s)
  Naoki Yamada, Naoki Yamada, Yuto Honda, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  14th US-JAPAN Symposium on Drug Delivery Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 革新的オリゴ核酸送達システムの実現に向けた材料設計2017
- Author(s)
  西山伸宏
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Design of functional polymers for smart nanomedicine2017
- Author(s)
  西山伸宏
- Organizer
  5th International Symposium on Smart Biomaterials
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 2-Nitrobenzenesulfonamide group that responds to intracellular redox potential with enhanced photostability for a construction of polymer-siRNA conjugate system2017
- Author(s)
  Hiroyasu Takemoto, Huang Chih-Hao, Takahiro Nomoto, Keishiro Tomoda, Makoto Matsui, Nobuhiro Nishiyama
- Organizer
  The 34th International Conference of Photopolymer Science and Technology (ICPST-34)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] がん選択的に相互作用するグルタミン担持高分子の創製と機能評価2017
- Author(s)
  山田直生, 本田雄士，武元宏泰，野本貴大，松井誠，友田敬士郎，西山伸宏
- Organizer
  第39回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 11th Annual Symposium on Nanobiotechnology 20172017
- Author(s)
  N. Nishiyama
- Organizer
  Kawasaki City Industrial Promotion Hall, Kawasaki City
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki City
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] ミトコンドリア呼吸鎖阻害剤を腫瘍組織に送達するための高分子ミセルの開発2017
- Author(s)
  劉暁夢、武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] スマート機能型DDSのための機能性高分子設計2017
- Author(s)
  西山伸宏
- Organizer
  高分子学会関東支部バイオと科学の融合領域
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism2017
- Author(s)
  Yuto Honda, Naoki Yamada, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  253rd American Chemical Society National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] ゲムシタビンのポリアミノ酸への可逆的担持に基づく消化器毒性低減及び制がん効果向上2017
- Author(s)
  武元宏泰, 稲葉高徳, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 腫瘍内pHに応答する双性イオン型ポリマーの設計とDDS応用-ベタイン内アニオン性基の影響-2017
- Author(s)
  左久間隼矢、Abdul-Hackam RANNEH, 武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] ナノ材料を基盤とするスマート診断・治療システムの開発2017
- Author(s)
  西山伸宏
- Organizer
  ナレッジキャピタル超学校
- Invited
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 光増感剤結合型高分子における多岐環状ＲＧＤペプチドの腫瘍集積性と腫瘍内分布への効果の検討2017
- Author(s)
  Dou Xuebo、野本貴大、武元宏泰、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Glutamine-functionalized polymer for tumor-selective high affinity by sensing dense glutamine transporters associated with aberrant metabolism2017
- Author(s)
  Naoki Yamada, Naoki Yamada, Yuto Honda, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  14th US-JAPAN Symposium on Drug Delivery Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 光増感剤結合型高分子における多岐環状ＲＧＤペプチドの腫瘍集積性と腫瘍内分布への効果の検討2017
- Author(s)
  Dou Xuebo、野本貴大、武元宏泰、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 革新的オリゴ核酸送達システムの実現に向けた材料設計2017
- Author(s)
  西山伸宏
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of polymer-based nanodevices for innovative medicine2017
- Author(s)
  N. Nishiyama
- Organizer
  Snowbird Symposium for Dr. Kopecek
- Place of Presentation
  Snowbird, Utah, U.S.A.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters2017
- Author(s)
  Naoki Yamada, Yuto Honda, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyamam
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Design of functional polymers for cancer diagnosis and therapy2017
- Author(s)
  西山伸宏
- Organizer
  化学系学協会東北大会高分子コロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Design of synthetic polymer toward achieving a selective high affinity to tumor cells by interacting with dense glutaminolysis-related transporters2017
- Author(s)
  Naoki Yamada, Yuto Honda, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyamam
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 腫瘍指向性ステルス高分子の開発とDDS への応用-ベタイン構造内アニオン性基の影響-2017
- Author(s)
  左久間隼矢、Abdul-Hackam RANNEH, 武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Development of polymer-based nanodevices for innovative medicine2017
- Author(s)
  N. Nishiyama
- Organizer
  Snowbird Symposium for Dr. Kopecek
- Place of Presentation
  Snowbird, Utah, U.S.A.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] Design of functional polymers for cancer diagnosis and therapy2017
- Author(s)
  西山伸宏
- Organizer
  化学系学協会東北大会高分子コロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism2017
- Author(s)
  Yuto Honda, Naoki Yamada, Hiroyasu Takemoto, Takahiro Nomoto, Makoto Matsui, Keishiro Tomoda, Nobuhiro Nishiyama
- Organizer
  253rd American Chemical Society National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 腫瘍指向性ステルス高分子の開発とDDS への応用-ベタイン構造内アニオン性基の影響-2017
- Author(s)
  左久間隼矢、Abdul-Hackam RANNEH, 武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] ミトコンドリア呼吸鎖阻害剤を腫瘍組織に送達するための高分子ミセルの開発2017
- Author(s)
  劉暁夢、武元宏泰・野本貴大・松井誠・友田敬士郎・西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] がん特異的代謝に着想した外殻にグルタミンを有する高分子ミセルの開発2017
- Author(s)
  真貝太規、山田直生、武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] がん代謝に着想した表層にグルタミンを有する高分子ミセル型薬物送達システムの開発2017
- Author(s)
  真貝　太規、山田直生, 武元宏泰, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] がん特異的代謝に着想した外殻にグルタミンを有する高分子ミセルの開発2017
- Author(s)
  真貝太規、山田直生、武元宏泰、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子年次大会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of smart polymers and nanodevices for innovative medicine”, International Symposium on Materials for Chemistry and Engineering (IMCE2017)2017
- Author(s)
  N. Nishiyama
- Organizer
  Symposium on Materials for Chemistry and Engineering (IMCE2017)
- Place of Presentation
  Chikushi Hall (C-CUBE), Kyushu University, Fukuoka
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of smart nanomachines for cancer imaging and minimally invasive treatment2017
- Author(s)
  N. Nishiyama
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki City
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 糖骨格を有する制がん剤のポリアミノ酸への可逆的担持と薬効向上及び消化器毒性低減2017
- Author(s)
  武元宏泰、稲葉高徳、野本貴大、松井誠、友田敬士郎、西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of smart nanomachines for cancer imaging and minimally invasive treatment2017
- Author(s)
  N. Nishiyama
- Organizer
  11th Annual Symposium on Nanobiotechnology 2017
- Place of Presentation
  Kawasaki City Industrial Promotion Hall, Kawasaki City
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] がん代謝に着想した表層にグルタミンを有する高分子ミセル型薬物送達システムの開発2017
- Author(s)
  真貝　太規、山田直生, 武元宏泰, 野本貴大, 松井誠, 友田敬士郎, 西山伸宏
- Organizer
  第66回高分子討論会
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 高分子ナノテクノロジーを基盤とするがん診断・治療システムの創製2016
- Author(s)
  西山伸宏
- Organizer
  第2回神奈川県ヘルスケア・ニューフロティア講座次世代医療に向けた医理工学融合研究とその産業応用
- Place of Presentation
  東京工業大学大岡山キャンパス, 東京都
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 高分子ミセル型ナノマシンが拓く未来医療2016
- Author(s)
  西山伸宏
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール, 川崎市
- Invited
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 高分子ナノテクノロジーを基盤とする革新的がん診断・治療システムの創出2016
- Author(s)
  西山伸宏
- Organizer
  第51回天然物化学談話会
- Place of Presentation
  湯沢東映ホテル, 新潟県南魚沼郡
- Invited
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 高分子ナノテクノロジーを基盤とした革新的ナノ診断・治療システムの開発2016
- Author(s)
  西山伸宏
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  キッセイ文化ホール, 松本市
- Invited
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 精密合成高分子材料を基盤するがん診断・治療ナノマシンの創製2016
- Author(s)
  西山伸宏
- Organizer
  科研費新学術領域「分子ロボティクス」公開シンポジウム
- Place of Presentation
  タワーホール船堀, 東京都
- Invited
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 高分子ミセル型ナノ医薬品の開発-アカデミアからの取り組み-2016
- Author(s)
  西山伸宏
- Organizer
  第32回日本DDS学会学術大会
- Place of Presentation
  グランシップ, 静岡市
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 高分子ミセル型ナノマシンが拓く未来医療2016
- Author(s)
  西山伸宏
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  ミューザ川崎シンフォニーホール, 川崎市
- Invited
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] ナノテクノロジーが拓く未来医療 -体内病院の実現を目指して-2016
- Author(s)
  西山伸宏
- Organizer
  第11回四大学連合文化講演会
- Place of Presentation
  一橋講堂学術総合センター, 東京都
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] ナノテクノロジーが拓く未来医療 -体内病院の実現を目指して-2016
- Author(s)
  西山伸宏
- Organizer
  第11回四大学連合文化講演会
- Place of Presentation
  一橋講堂学術総合センター, 東京都
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 高分子ナノテクノロジーを基盤とするがん診断・治療システムの創製2016
- Author(s)
  西山伸宏
- Organizer
  第2回神奈川県ヘルスケア・ニューフロティア講座次世代医療に向けた医理工学融合研究とその産業応用
- Place of Presentation
  東京工業大学大岡山キャンパス, 東京都
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 高分子ナノテクノロジーを基盤とする革新的がん診断・治療システムの創出2016
- Author(s)
  西山伸宏
- Organizer
  第51回天然物化学談話会
- Place of Presentation
  湯沢東映ホテル, 新潟県南魚沼郡
- Invited
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 高分子ミセル型ナノ医薬品の開発-アカデミアからの取り組み-2016
- Author(s)
  西山伸宏
- Organizer
  第32回日本DDS学会学術大会
- Place of Presentation
  グランシップ, 静岡市
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 精密合成高分子材料を基盤するがん診断・治療ナノマシンの創製2016
- Author(s)
  西山伸宏
- Organizer
  科研費新学術領域「分子ロボティクス」公開シンポジウム
- Place of Presentation
  タワーホール船堀, 東京都
- Invited
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] ナノテクノロジーが拓く未来医療 -体内病院の実現を目指して-2016
- Author(s)
  西山伸宏
- Organizer
  第11回四大学連合文化講演会
- Place of Presentation
  一橋講堂学術総合センター, 東京都
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 高分子ナノテクノロジーを基盤とするがん診断・治療システムの創製2016
- Author(s)
  西山伸宏
- Organizer
  第2回神奈川県ヘルスケア・ニューフロティア講座次世代医療に向けた医理工学融合研究とその産業応用
- Place of Presentation
  東京工業大学大岡山キャンパス, 東京都
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of supramolecular nanodevices for cancer diagnostics and therapy2016
- Author(s)
  N. Nishiyama
- Organizer
  he Korean Academy of Science and Technology (KAST) Symposium for Young Scientists in Drug Delivery: Redirecting the Research Field
- Place of Presentation
  KIST, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16407
[Presentation] 高分子ナノテクノロジーを基盤とするがん診断・治療システムの創製2016
- Author(s)
  西山伸宏
- Organizer
  第2回神奈川県ヘルスケア・ニューフロティア講座次世代医療に向けた医理工学融合研究とその産業応用
- Place of Presentation
  東京工業大学大岡山キャンパス, 東京都
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] Development of supramolecular nanodevices for cancer diagnostics and therapy2016
- Author(s)
  N. Nishiyama
- Organizer
  The Korean Academy of Science and Technology (KAST) Symposium for Young Scientists in Drug Delivery: Redirecting the Research Field
- Place of Presentation
  KIST, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15104
[Presentation] 精密合成高分子材料を基盤するがん診断・治療ナノマシンの創製2016
- Author(s)
  西山伸宏
- Organizer
  科研費新学術領域「分子ロボティクス」公開シンポジウム
- Place of Presentation
  タワーホール船堀, 東京都
- Invited
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 高分子ナノテクノロジーを基盤とした革新的ナノ診断・治療システムの開発2016
- Author(s)
  西山伸宏
- Organizer
  日本薬物動態学会　第31回年会
- Place of Presentation
  キッセイ文化ホール, 松本市
- Invited
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] Development of supramolecular nanodevices for cancer diagnostics and therapy2016
- Author(s)
  N. Nishiyama
- Organizer
  The Korean Academy of Science and Technology (KAST) Symposium for Young Scientists in Drug Delivery: Redirecting the Research Field
- Place of Presentation
  KIST, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16058
[Presentation] 高分子ナノテクノロジーを基盤とした革新的ナノ診断・治療システムの開発2016
- Author(s)
  西山伸宏
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  キッセイ文化ホール, 松本市
- Invited
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of supramolecular nanodevices for cancer diagnosis and therapy2015
- Author(s)
  N. Nishiyama
- Organizer
  The 5th Asian Biomaterials Congress (2015 ABMC5)
- Place of Presentation
  Chientan Youth Activity Center, Taipei, Taiwan
- Year and Date
  2015-05-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of supramolecular nanodevices for cancer diagnosis and therapy2015
- Author(s)
  N. Nishiyama
- Organizer
  Recent Advances in Drug Delivery Systems 17th International Symposium
- Place of Presentation
  Salt Lake City Marriott City Center, Salt Lake City, U.S.A.
- Year and Date
  2015-06-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of polymeric nanocarriers for targeted siRNA delivery2015
- Author(s)
  K. Miyata, H. -J. Kim, N. Nishiyama, K. Kataoka
- Organizer
  IUPAC-2015
- Place of Presentation
  Bexco (Busan, Korea)
- Year and Date
  2015-08-13
- Description
  【発表確定】
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子ナノテクノロジーを基盤とした革新的ナノメディシンの創製2015
- Author(s)
  西山伸宏
- Organizer
  第10回超分子研究会講座
- Place of Presentation
  上智大学, 東京
- Year and Date
  2015-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] 1分子siRNA封入ユニットポリイオンコンプレックスの精密構造設計2015
- Author(s)
  宮田完二郎, 林光太朗, 茶谷洋行, 渡邉秀美代, 藤加珠子, 福島重人, W. Lan, H. -J. Kim, 武元宏泰, 西山伸宏, 長田健介, 片岡一則
- Organizer
  第64回高分子討論会
- Place of Presentation
  東北大学川内キャンパス(宮城県仙台市)
- Year and Date
  2015-09-17
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] ナノバイオテクノロジーが拓く新生代ドラッグデリバリーシステム2015
- Author(s)
  西山伸宏
- Organizer
  第25回日本光線力学学会
- Place of Presentation
  京王プラザホテル, 東京
- Year and Date
  2015-07-10
- Invited
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of enzyme-loaded polyion complex vesicles for in vivo nanoreactor2015
- Author(s)
  Y. Anraku, M. Kamiya, S. Tanaka, T. Nomoto, K. Toh, Y. Matsumoto, S. Fukushima, D. Sueyoshi, A. Kishimura, M. Kano, Y. Urano, N. Nishiyama, K. Kataoka
- Organizer
  THE INTERNATIONAL CHEMICAL CONGRESS OF PACIFIC BASIN SOCIETIES (PACIFICHEM2015)
- Place of Presentation
  Hawaii Convention Center (Hawaii, USA)
- Year and Date
  2015-12-15
- Description
  【発表確定】
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子の精密設計に基づく革新的がん診断・治療システムの創製2015
- Author(s)
  西山伸宏
- Organizer
  第24回DDSカンファランス
- Place of Presentation
  静岡市東部勤労者福祉センター, 静岡
- Year and Date
  2015-09-04
- Invited
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] N置換ポリアスバルタマイド側鎖の化学構造がmRNAポリプレックスの細胞内安定性及び発現持続性に及ぼす影響2015
- Author(s)
  内田寛邦, 位高啓史, 宮田完二郎, 西山伸宏, 片岡一則
- Organizer
  第1回日本核酸医薬学会大会
- Place of Presentation
  京都テルサ(京都府京都市)
- Year and Date
  2015-12-01
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of supramolecular nanodevices for cancer diagnosis and therapy2015
- Author(s)
  N. Nishiyama
- Organizer
  World Engineering Conference and Convention 2015 (WECC2015)
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Year and Date
  2015-12-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04635
[Presentation] Development of supramolecular nanocarriers for cancer diagnosis and therapy2014
- Author(s)
  N. Nishiyama
- Organizer
  Emerging Biomaterials 2014
- Place of Presentation
  KAIST Institute, Seoul, Korea
- Year and Date
  2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] Biological functionalities of polymeric micelle systems for targeting cancer2014
- Author(s)
  N. Nishiyama
- Organizer
  The European Summit for Clinical Nanomedicine 2014(6th CLINAM2014)
- Place of Presentation
  Congress Center Basel(Basel, Switzerland)
- Year and Date
  2014-06-23
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Biological functionalities of polymeric micelle systems for targeting cancer2014
- Author(s)
  N. Nishiyama
- Organizer
  The European Summit for Clinical Nanomedicine 2014 (6th CLINAM 2014)
- Place of Presentation
  Congress Center Basel, Basel, Switzerland
- Year and Date
  2014-06-23
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] 高分子ミセル型ナノ医薬品の研究開発2014
- Author(s)
  西山伸宏
- Organizer
  新製剤技術とエンジニアリングを考える会　第12回技術講演会
- Place of Presentation
  京都国際会館, 京都市, 京都府
- Year and Date
  2014-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] 生体イメージングを活用したナノDDS設計2014
- Author(s)
  西山伸宏
- Organizer
  疾患克服を目指したケミカルバイオフォトニクス技術　第87回日本生化学会大会
- Place of Presentation
  京都国際会館, 京都市, 京都府
- Year and Date
  2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] 生体イメージングを活用したナノDDS設計2014
- Author(s)
  西山伸宏
- Organizer
  疾患克服を目指したケミカルバイオフォトニクス技術　第87回日本生化学会大会
- Place of Presentation
  京都国際会館, 京都市, 京都府
- Year and Date
  2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Development of supramolecular nanocarriers for cancer diagnosis and therapy2014
- Author(s)
  N. Nishiyama
- Organizer
  Emerging Biomaterials 2014
- Place of Presentation
  KAIST Institute, Seoul, Korea
- Year and Date
  2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] がんの診断・治療のための高分子ミセル型DDSの開発2014
- Author(s)
  西山伸宏
- Organizer
  本病院薬剤師会東北ブロック第４回学術大会
- Place of Presentation
  仙台国際センター, 仙台市, 宮城県
- Year and Date
  2014-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] Biological functionalities of polymeric micelle systems for targeting cancer2014
- Author(s)
  N. Nishiyama
- Organizer
  The European Summit for Clinical Nanomedicine 2014 (6th CLINAM 2014)
- Place of Presentation
  Congress Center Basel, Basel, Switzerland
- Year and Date
  2014-06-23
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] 高分子ミセル型ナノ医薬品の研究開発2014
- Author(s)
  西山伸宏
- Organizer
  新製剤技術とエンジニアリングを考える会　第12回技術講演会
- Place of Presentation
  京都国際会館, 京都市, 京都府
- Year and Date
  2014-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] がんの診断・治療のための高分子ミセル型DDSの開発2014
- Author(s)
  西山伸宏
- Organizer
  日本病院薬剤師会東北ブロック第４回学術大会
- Place of Presentation
  仙台国際センター, 仙台市, 宮城県
- Year and Date
  2014-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] がんの診断・治療のための高分子ミセル型DDSの開発2014
- Author(s)
  西山伸宏
- Organizer
  日本病院薬剤師会東北ブロック第４回学術大会
- Place of Presentation
  仙台国際センター, 仙台市, 宮城県
- Year and Date
  2014-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Development of supramolecular nanocarriers for cancer diagnosis and therapy2014
- Author(s)
  N. Nishiyama
- Organizer
  2013 International Advanced Drug Delivery Symposium
- Place of Presentation
  Industrial Technology Research Institute (Hsinchu, Taiwan)
- Year and Date
  2014-02-28
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子ナノテクノロジーを基盤とするナノ医薬品の開発2014
- Author(s)
  西山伸宏
- Organizer
  第10回つくばがん遺伝子治療研究会
- Place of Presentation
  ステーションコンファレンス東京, 東京
- Year and Date
  2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] 高分子ナノテクノロジーを基盤とするナノ医薬品の開発2014
- Author(s)
  西山伸宏
- Organizer
  第10回つくばがん遺伝子治療研究会
- Place of Presentation
  ステーションコンファレンス東京, 東京
- Year and Date
  2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] 高分子ミセル型ナノ医薬品の研究開発2014
- Author(s)
  西山伸宏
- Organizer
  新製剤技術とエンジニアリングを考える会第12回技術講演会
- Place of Presentation
  京都国際会館, 京都市, 京都府
- Year and Date
  2014-06-23
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] Development of supramolecular nanocarriers for cancer diagnosis and therapy2014
- Author(s)
  N. Nishiyama
- Organizer
  Emerging Biomaterials 2014
- Place of Presentation
  KAIST Institute, Seoul, Korea
- Year and Date
  2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] 高分子ナノテクノロジーを基盤とするナノ医薬品の開発2014
- Author(s)
  西山伸宏
- Organizer
  第10回つくばがん遺伝子治療研究会
- Place of Presentation
  ステーションコンファレンス東京, 東京
- Year and Date
  2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] Development of supramolecular nanocarriers for cancer diagnosis and therapy2014
- Author(s)
  N. Nishiyama
- Organizer
  Emerging Biomaterials 2014
- Place of Presentation
  KAIST Institute(Daejeon, Korea)
- Year and Date
  2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 生体イメージングを活用したナノDDS設計2014
- Author(s)
  西山伸宏
- Organizer
  疾患克服を目指したケミカルバイオフォトニクス技術　第87回日本生化学会大会
- Place of Presentation
  京都国際会館, 京都市, 京都府
- Year and Date
  2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] Biological functionalities of polymeric micelle systems for targeting cancer2014
- Author(s)
  N. Nishiyama
- Organizer
  The European Summit for Clinical Nanomedicine 2014 (6th CLINAM 2014)
- Place of Presentation
  Congress Center Basel, Basel, Switzerland
- Year and Date
  2014-06-23
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] Enhanced nucleic acids delivery by fine-tuning repeated aminoethylene structures in polyaspartamide side chain2013
- Author(s)
  K. Miyata, H. Uchida, N. Nishiyama, K. Kataoka
- Organizer
  The 4th Asian Symposium on Advanced Materials - Chemistry, Physics & Biomedicine of Functional and Novel Materials
- Place of Presentation
  National Taiwan University of Science and Technology (Taipei, Taiwan)
- Year and Date
  2013-10-23
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Design of polymeric nanomaterials for enhanced small RNA delivery2013
- Author(s)
  K. Miyata, Y. Maeda, K. Hayashi, H. Takemoto, N. Nishiyama, K. Kataoka
- Organizer
  The 15th Asian Chemical Congress
- Place of Presentation
  Resorts World Sentosa (Sentosa Gateway. Singapore)
- Year and Date
  2013-08-23
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 核酸医薬のデリバリーのための高分子ナノキャリアの設計2013
- Author(s)
  西山伸宏
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ(京都府、京都市)
- Year and Date
  2013-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] Design of REGylate poIyion complexes incorporating single siRNA molecule "Effect of chain lengths of PEG-polycation block copolymers on the complex structure and properties"2013
- Author(s)
  K. Osada, H. Chaya, S. Watanabe, H. Takemoto, N. Nishiyama, K. Miyata, K. Kataoka
- Organizer
  21st International Conference on Analytical Ultracentrifugation, Hydrodynamics, Thermodynamics and Complementary Methods (AUC2013)
- Place of Presentation
  Hotel New Akao (Atami, Shizuoka, Japan)
- Year and Date
  2013-09-28
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] がんの革新的診断・治療のためのスマート機能型高分子ミセルの開発2013
- Author(s)
  西山　伸宏
- Organizer
  BioJapan 2013
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] がんの革新的診断・治療のためのスマート機能型高分子ミセルの開発2013
- Author(s)
  西山　伸宏
- Organizer
  BioJapan 2013
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] Development of supramolecular nanocarriers for cancer diagnosis and therapy2013
- Author(s)
  N. Nishiyama
- Organizer
  2013 International Advanced Drug Delivery Symposium
- Place of Presentation
  ITRI （Taiwan）
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] 生体イメージングを活用したナノDDS設計2013
- Author(s)
  西山伸宏
- Organizer
  第22回日本バイオイメージング学会学術集会
- Place of Presentation
  東京大学大学院薬学系総合研究棟(東京都文京区)
- Year and Date
  2013-09-16
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 高分子ナノテクノロジーによるがんの診断・治療システムの創製2013
- Author(s)
  西山伸宏
- Organizer
  東京工業大学バイオマテリアルシンポジウム
- Place of Presentation
  東京工業大学すずかけホール(神奈川県、横浜市)
- Year and Date
  2013-09-19
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] 核酸医薬のデリバリーのための高分子ナノキャリアの設計2013
- Author(s)
  西山伸宏
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ(京都府京都市)
- Year and Date
  2013-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] Development of polymeric micellar nanocarriers for cancer diagnosis and therapy2013
- Author(s)
  N. Nishiyama
- Organizer
  RSC Publishing-iCeMS Joint International Symposium Cell-Material Integration and Biomaterial Science
- Place of Presentation
  Shiran Kaikan, Kyoto University (Kyoto)
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] DDS evaluation using intravital real-time laser scanning confocal microscopy2013
- Author(s)
  Y. Matsumoto, T. Nomoto, K. Toh, N. Nishiyama, T. Yamasoba, K. Kataoka
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center (Honolulu, Hawaii, USA)
- Year and Date
  2013-07-21
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] がんの革新的診断・治療のためのスマート機能型高分子ミセルの開発2013
- Author(s)
  西山伸宏
- Organizer
  BioJapan 2013
- Place of Presentation
  パシフィコ横浜(神奈川県、横浜市)
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] Development of supramolecular nanocarriers for cancer diagnosis and therapy2013
- Author(s)
  N. Nishiyama
- Organizer
  2013 International Advanced Drug Delivery Symposium
- Place of Presentation
  ITRI (Taiwan)
- Year and Date
  2013-05-02
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] 高分子ナノテクノロジーによるがんの診断・治療システムの創製2013
- Author(s)
  西山　伸宏
- Organizer
  東京工業大学　バイオマテリアルシンポジウム
- Place of Presentation
  東京工業大学すずかけホール（神奈川県、横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Development of polymeric micellar nanocarriers for cancer diagnosis and therapy2013
- Author(s)
  N. Nishiyama
- Organizer
  The 4th Asian Biomaterials Congress
- Place of Presentation
  The Hong Kong University of Science and Technology (Hong Kong, China)
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Development of polymeric micellar nanocarriers for cancer diagnosis and therapy2013
- Author(s)
  N. Nishiyama
- Organizer
  The 4^<th> Asian Biomaterials Congress
- Place of Presentation
  The Hong Kong University of Science and Technology (Hong Kong, China)
- Year and Date
  2013-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] Development of polymeric micellar nanocarriers for cancer diagnosis and therapy2013
- Author(s)
  N. Nishiyama
- Organizer
  The 4th Asian Biomaterials Congress
- Place of Presentation
  The Hong Kong University of Science and Technology (Hong Kong, China)
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] Development of supramolecular nanocarriers for cancer diagnosis and therapy2013
- Author(s)
  N. Nishiyama
- Organizer
  2013 International Advanced Drug Delivery Symposium
- Place of Presentation
  ITRI （Taiwan）
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] がんの診断・治療のための高分子ミセル型DDSの開発2013
- Author(s)
  西山伸宏
- Organizer
  製剤機械技術学会第23回大会
- Place of Presentation
  ニッショーホール(東京都、港区)
- Year and Date
  2013-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-13F03042
[Presentation] がんの診断・治療のための高分子ミセル型DDSの開発2013
- Author(s)
  西山　伸宏
- Organizer
  製剤機械技術学会　第23回大会
- Place of Presentation
  ニッショーホール（東京都、港区）
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] Development of polymeric micellar nanocarriers for cancer diagnosis and ther2013
- Author(s)
  N. Nishiyama
- Organizer
  The 4th Asian Biomaterials Congress
- Place of Presentation
  The Hong Kong University of Science and Technology (Clear Water Bay, Hong Kong)
- Year and Date
  2013-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-25000006
[Presentation] 核酸医薬のデリバリーのための高分子ナノキャリアの設計2013
- Author(s)
  西山　伸宏
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都府、京都市）
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] がんの診断・治療のための高分子ミセル型DDSの開発2013
- Author(s)
  西山　伸宏
- Organizer
  製剤機械技術学会　第23回大会
- Place of Presentation
  ニッショーホール（東京都、港区）
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] 高分子ナノテクノロジーによるがんの診断・治療システムの創製2013
- Author(s)
  西山　伸宏
- Organizer
  東京工業大学　バイオマテリアルシンポジウム
- Place of Presentation
  東京工業大学すずかけホール（神奈川県、横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-25670010
[Presentation] がんの診断・治療のためのスマート機能型高分子ミセルの開発2012
- Author(s)
  西山伸宏
- Organizer
  第7回日本分子イメージング学会総会・学術集会
- Place of Presentation
  アクトシティ浜松（静岡県）
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] がんの革新的診断・治療のためのスマート機能型高分子ミセルの開発2012
- Author(s)
  西山伸宏
- Organizer
  日本薬剤学会　第27年会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Design of polymeric micelles for targeting intractable cancers2012
- Author(s)
  N. Nishiyama
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] がんの革新的診断・治療のためのスマート機能型高分子ミセルの開発2012
- Author(s)
  西山伸宏
- Organizer
  創剤フォーラム第18回シンポジウム
- Place of Presentation
  タワーホール船堀（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Design of smart nanocarriers for photosensitizer delivery2011
- Author(s)
  西山伸宏
- Organizer
  13^<th> World Congress of International Photodynamic Association (IPA)
- Place of Presentation
  Innsbruck Convention Center(Innsbruck,オーストリア)(招待講演)
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Block co-olymer based gene therapy for disseminated cancer : Perspective toClinical Trials. 17th2011
- Author(s)
  Nakano K, Kumagai M, Shimoda S, Wakabayash i R, Nishiyama N, Kataoka K
- Organizer
  日本遺伝子治療学会
- Place of Presentation
  福岡市
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-21390374
[Presentation] Development of functional polymeric micelles for cancer diagnosis and therapy2011
- Author(s)
  N. Nishiyama
- Organizer
  Singapore-Japan "Bioelectronics" Workshop
- Place of Presentation
  Keihanna plaza, Kyoto, Japan
- Year and Date
  2011-08-12
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Development of functional polymeric micelles for cancer diagnosis and therapy2011
- Author(s)
  N. Nishiyama
- Organizer
  2011 International Symposium on Intelligent Drug Delivery Systems
- Place of Presentation
  KIST, Seoul, Korea, April
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Development of photosensitizer drug delivery system for cancer theranostics2011
- Author(s)
  N. Nishiyama
- Organizer
  28th International Conference of Photopolymer Science and Technology
- Place of Presentation
  University Convention Hall, Chiba University, Chiba
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] 高分子集合体を利用したターゲティング型DDSの開発2011
- Author(s)
  西山伸宏
- Organizer
  第24回インターフェックスジャパン
- Place of Presentation
  東京ビッグサイト(東京都江東区)(招待講演)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] 高分子集合体を利用したターゲティング型DDSの開発2011
- Author(s)
  西山伸宏
- Organizer
  第24回インターフェックスジャパン
- Place of Presentation
  東京ビッグサイト(東京都江東区)(招待講演)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Development of functional polymeric micelles for cancer diagnosis and therapy2011
- Author(s)
  西山伸宏
- Organizer
  The 14th Asian Chemical Congress
- Place of Presentation
  Queen Sirikit National Convention Center(タイ,バンコク)(招待講演)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Development of functional polymeric micelles for cancer diagnosis and therapy2011
- Author(s)
  西山伸宏
- Organizer
  The 14th Asian Chemical Congress
- Place of Presentation
  Queen Sirikit National Convention Center(タイ,バンコク)(招待講演)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Development of functional polymeric micelles for cancer diagnosis and therapy2011
- Author(s)
  西山伸宏
- Organizer
  2011 International Symposium on Intelligent Drug Delivery Systems
- Place of Presentation
  KIST(ソウル市,韓国)(招待講演)
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Light-responsive nanodevices for imaging and therapy of malignant tumors2011
- Author(s)
  N. Nishiyama, et al
- Organizer
  FIRST International Symposium Medical Innovation of 21st Century
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23300174
[Presentation] Development of polymeric micelles for innovative cancer diagnosis and treatment2011
- Author(s)
  西山伸宏
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県,名古屋市)(招待講演)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Development of functional polymeric micelles for cancer diagnosis and therapy2011
- Author(s)
  西山伸宏
- Organizer
  Singapore-Japan "Bioelectronics" Workshop
- Place of Presentation
  けいはんなプラザ(京都府,相楽郡)(招待講演)
- Year and Date
  2011-08-12
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Development of functional polymeric micelles for cancer diagnosis and therapy2011
- Author(s)
  西山伸宏
- Organizer
  2011 International Symposium on Intelligent Drug Delivery Systems
- Place of Presentation
  KIST(ソウル市,韓国)(招待講演)
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Development of functional polymeric micelles for cancer diagnosis and therapy2011
- Author(s)
  西山伸宏
- Organizer
  Singapore-Japan "Bioelectronics" Workshop
- Place of Presentation
  けいはんなプラザ(京都府,相楽郡)(招待講演)
- Year and Date
  2011-08-12
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Block co-polymer based gene therapy for disseminated cancer : Perspective to Clinical Trials2011
- Author(s)
  Nakano K, Kumagai M, Shimoda S, Wakabayashi R, Nishiyama N, Kataoka K
- Organizer
  17^<th> Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Fukuoka
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-21390374
[Presentation] Development of polymeric micelles for innovative cancer diagnosis and treatment2011
- Author(s)
  西山伸宏
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県,名古屋市)(招待講演)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Design of smart nanocarriers for photosensitizer delivery2011
- Author(s)
  N. Nishiyama, K. Kataoka
- Organizer
  13^<th> World Congress of International Photodynamic Association(IPA)
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Polymeric micelles for photodynamic diagnosis and therapy2011
- Author(s)
  N. Nishiyama, Y. Morimoto, K. Kataoka
- Organizer
  The 15th International Symposium on Recent Advances in Drug Delivery Systems
- Place of Presentation
  Sheraton Hotel, Salt Lake City, Utah, USA
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Design of smart nanocarriers for photosensitizer delivery2011
- Author(s)
  西山伸宏
- Organizer
  13^<th> World Congress of International Photodynamic Association (IPA)
- Place of Presentation
  Innsbruck Convention Center(Innsbruck,オーストリア)(招待講演)
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] ナノスケールのトロイの木馬として機能する高分子ミセルによる薬剤耐性の克服2011
- Author(s)
  西山伸宏
- Organizer
  第13回図書館総合展フォーラム
- Place of Presentation
  パシフィコ横浜(神奈川県、横浜市)(招待講演)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] ブロックポリマーを用いた播種癌に対する遺伝子治療:臨床試験に向けての展望2011
- Author(s)
  中野賢二、熊谷康顕、下田真也、若林里衣、西山伸宏、片岡一則
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21390374
[Presentation] Development of functional polymeric micelles for cancer diagnosis and therapy2011
- Author(s)
  N. Nishiyama
- Organizer
  The 14th Asian Chemical Congress(14-ACC)
- Place of Presentation
  Bangkok, Thailand
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] ナノスケールのトロイの木馬として機能する高分子ミセルによる薬剤耐性の克服2011
- Author(s)
  西山伸宏
- Organizer
  第13回図書館総合展フォーラム
- Place of Presentation
  パシフィコ横浜(神奈川県,横浜市)(招待講演)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-23390009
[Presentation] Development of polymeric micelles for photodynamic diagnosis and treatment of solid tumors2010
- Author(s)
  西山伸宏, et al.
- Organizer
  Symposium on Biomedical Polymers for Drug Delivery
- Place of Presentation
  University of Utah, USA
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 高分子ミセル型DDSと光照射システムの融合による革新的PDT2010
- Author(s)
  西山伸宏, 他2名
- Organizer
  第31回日本レーザー医学会総会
- Place of Presentation
  ウインクあいち,愛知
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] 光線力学治療のための光増感剤内包高分子ミセルの開発2010
- Author(s)
  西山伸宏
- Organizer
  日本薬学会第130年会
- Place of Presentation
  ホテルグランヴィア, 岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Nanocarrier-mediated photodynamic diagnosis and therapy of malignant tumors, New Directions In Nanotheranostics : Imaging, Biosensors, Materials and DNA Technologies2010
- Author(s)
  N. Nishiyama, Y. Morimoto, K. Kataoka
- Organizer
  4^<th> Annual Symposium on Nanobiotechnology
- Place of Presentation
  Ludwig-Maximilians University, Munich, Germany
- Year and Date
  2010-10-06
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] 高分子ミセルを利用した細胞内薬物分布の時空間制御に基づく耐性がんの克服2010
- Author(s)
  西山伸宏, 他4名
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪国際交流センター,大阪
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] 高分子集合体を基盤とする生体ナノ環境可視化システム2010
- Author(s)
  西山伸宏
- Organizer
  生体ナノ環境の時空間制御を目指して
- Place of Presentation
  北海道大学大学院薬学研究院・臨床薬学講義室, 北海道
- Year and Date
  2010-01-05
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 光線力学治療のための光増感剤内包高分子ミセルの開発2010
- Author(s)
  西山伸宏
- Organizer
  日本薬学会第130年会シンポジウム「異分野技術の融合による次世代の医療基盤技術の構築に向けて」
- Place of Presentation
  ホテルグランヴィア, 岡山
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Development of smart polymeric micelles for innovative cancer therapy2010
- Author(s)
  N. Nishiyama, H. Cabral, K. Kataoka
- Organizer
  World Congress of Pharmacy and Pharmaceutical Sciences
- Place of Presentation
  Lisbon, Portugal
- Year and Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] オキサリプラチン耐性克服のための細胞内環境応答型高分子ミセルの開発2010
- Author(s)
  西山伸宏, 他5名
- Organizer
  第32回日本バイオマテリアル学会
- Place of Presentation
  グランドプリンスホテル広島,広島
- Year and Date
  2010-11-30
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Development of polymeric micelles for photodynamic diagnosis and treatment of solid tumors2010
- Author(s)
  N.Nishiyama, et al.
- Organizer
  Symposium on Biomedical Polymers for Drug Delivery
- Place of Presentation
  University of Utah, USA
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] 光線力学治療のための光増感剤内包高分子ミセルの開発2010
- Author(s)
  西山伸宏
- Organizer
  日本薬学会第130年会
- Place of Presentation
  ホテルグランヴィア,岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] 細胞内環境に応答する白金錯体制がん剤内包高分子ミセルの創製2010
- Author(s)
  西山伸宏, 他4名
- Organizer
  第59回高分子学会年次大会
- Place of Presentation
  パシフィコ横浜,神奈川
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Nanocarrier-mediated photodynamic diagnosis and therapy of malignant tumors2010
- Author(s)
  N.Nishiyama, et al.
- Organizer
  4^<th> Annual Symposium on Nanobiotechnology "New Direciions In Nanotheranostics : Imaging, Biosensors, Materials and DNA Technologies"
- Place of Presentation
  Ludwig-Maximilians University, Munich, Germany
- Year and Date
  2010-10-06
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] がん深部への遺伝子・薬剤デリバリーのためのナノキャリアの設計2009
- Author(s)
  西山伸宏, 他6名
- Organizer
  第58回高分子討論会
- Place of Presentation
  熊本大学黒髪キャンパス, 熊本
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Development of polymeric micelles for innovative cancer therapy2009
- Author(s)
  西山伸宏
- Organizer
  第68回日本癌学会
- Place of Presentation
  パシフィコ横浜, 神奈川
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Development of dendrimer phthalocyanine-loaded polymeric micelle for detection and treatment of microcarcinoma2009
- Author(s)
  N.Nishiyama, et al.
- Organizer
  8th International Symposium on Frontiers in Biomedical Polymers(FBPS09)
- Place of Presentation
  東レ研修センター、三島、静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Block copolymer micelles as smart supramolecular nanodevices for tumor targeting2009
- Author(s)
  N. Nishiyama
- Organizer
  The 36th Annual Meeting and Exposition of the Controlled Release Society
- Place of Presentation
  Bella Center, Copenhagen Denmark
- Year and Date
  2009-07-19
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Development of polymeric micelles for innovative cancer therapy2009
- Author(s)
  西山伸宏
- Organizer
  第68回日本癌学会シンポジウム「ナノテクノロジーがもたらす新規がん治療」
- Place of Presentation
  パシフィコ横浜, 神奈川
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] がん標的治療のための高分子ミセル型DDSの開発2009
- Author(s)
  西山伸宏、片岡一則
- Organizer
  岡山肝癌研究会
- Place of Presentation
  岡山コンベンションセンター(岡山県)
- Year and Date
  2009-04-25
- Data Source
  KAKENHI-PROJECT-20240046
[Presentation] がん深部への遺伝子・薬剤デリバリーのためのナノキャリアの設計2009
- Author(s)
  西山伸宏, 他6名
- Organizer
  第58回高分子討論会
- Place of Presentation
  熊本大学黒髪キャンパス,熊本
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Development of dendirimer phthalocyanine-loaded polymericmicelles for diagnosis and treatment of microcarcinoma2009
- Author(s)
  N. Nishiyama, Y. Morimoto, K. Miyazaki, K. Urano, S. Horie, M. Kumagai, S. Fukushima, W.-D. Jang, K. Kataoka
- Organizer
  The 36th Annual Meeting and Exposition of the Controlled Release Society
- Place of Presentation
  Bella Center, Copenhagen Denmark
- Year and Date
  2009-07-12
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Development of dendrimer phthalocyanine-loaded polymeric micelle for detection and treatment of microcarcinoma2009
- Author(s)
  西山伸宏, et al.
- Organizer
  8th International Symposium on Frontiers in Biomedical Polymers(FBPS09)
- Place of Presentation
  東レ研修センター、三島、静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 高機能ポリマー材料を基盤とした遺伝子デリバリーシステムの設計2009
- Author(s)
  西山伸宏, 他5名
- Organizer
  第18回ポリマー材料フォーラム研究会
- Place of Presentation
  タワーホール船堀,東京
- Year and Date
  2009-11-24
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] Block copolymer micelles as smart supramolecular nanodevices for tumor targeting2009
- Author(s)
  西山伸宏
- Organizer
  The 36th Annual Meeting and Exposition of the Controlled Release Society
- Place of Presentation
  Bella Center, コベンハーゲン、デンマーク
- Year and Date
  2009-07-19
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Block copolymer micelles as smart supramolecular nanodevices for tum or targeting2009
- Author(s)
  N.Nishiyama
- Organizer
  The 36th Annual Meeting and Exposition of the Controlled Release Society
- Place of Presentation
  Bella Center,コベンハーゲン、デンマーク
- Year and Date
  2009-07-19
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] がん深部への遺伝子・薬剤デリバリーのためのナノキャリアの設計2009
- Author(s)
  西山伸宏, 韓ムリ, 大庭誠, カブラル・オラシオ, 狩野光伸, 片岡一則
- Organizer
  第58回高分子討論会
- Place of Presentation
  熊本大学黒髪キャンパス, 熊本
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 高機能ポリマー材料を基盤とした遺伝子デリバリーシステムの設計2009
- Author(s)
  西山伸宏, 他5名
- Organizer
  第18回ポリマー材料フォーラム研究会
- Place of Presentation
  タワーホール船堀, 東京
- Year and Date
  2009-11-24
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Block copolymer micelles as smart supramolecular nanodevices for tumor targeting2009
- Author(s)
  N. Nishiyama
- Organizer
  The 36th Annual Meeting and Exposition of the Controlled Release Society
- Place of Presentation
  Bella Center, Copenhagen Denmark
- Year and Date
  2009-07-19
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 全身投与による遺伝子デリバリーのための高分子ナノキャリア設計2009
- Author(s)
  西山伸宏、片岡一則
- Organizer
  JST新技術説明会
- Place of Presentation
  JST東京本部(東京都)
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-20240046
[Presentation] Development of polymeric micelles for innovative cancer therapy2009
- Author(s)
  西山伸宏
- Organizer
  第68回日本癌学会
- Place of Presentation
  パシフィコ横浜,神奈川
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21659299
[Presentation] 光応答型DDSを治療した革新的治療法の開発2008
- Author(s)
  西山伸宏
- Organizer
  レーザー学会第28回年次大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-01-31
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Design of functional drug delivery system based on polymer assemblies2008
- Author(s)
  N. Nishiyama, K. Kataoka
- Organizer
  10th European Symposium on Controlled Drug Delivery (ESCDD)
- Place of Presentation
  Noordwijk an Zee, The Netherlands
- Year and Date
  2008-04-02
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Stimuli-responsive drug and gene nanocarriers based on supramolecular assemblies2008
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  34th Annual Meeting & Exposition of the Controlled Release Society (CRS)
- Place of Presentation
  Long Beach, California
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Development of smart nanocarriers based on block copolymer assemblies", CNSI-CNBI Symposium on NanoBiotechnology CNSI-CNBI Symposium on NanoBiotechnology2008
- Author(s)
  N. Nishiyama
- Organizer
  CNSI-CNBI Symposium on NanoBiotechnology
- Place of Presentation
  東京大学医学部鉄門記念講堂
- Year and Date
  2008-09-09
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 高分子集合体を基盤とした遺伝子・siRNAデリバリーシステムの創製2008
- Author(s)
  西山伸宏, 片岡一則
- Organizer
  第24回日本DDS学会学術総会
- Place of Presentation
  六本木アカデミーヒルズ, 東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] PEG-ポリカチオンブロック共重合体とsiRNAによる超分子組織体形成とその機能特性2008
- Author(s)
  西山伸宏、片岡一則, 他6名
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪市立大学, 大阪
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 光を利用したドラッグデリバリーシステムの開発2008
- Author(s)
  西山伸宏
- Organizer
  第29回日本レーザー医学会総会
- Place of Presentation
  東京工科大学八王子キャンパス, 東京
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 空間構造を規制した超分子集合体の細胞内動態制御に基づく革新的光力学治療2008
- Author(s)
  西山伸宏、片岡一則, 他8名
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪市立大学, 大阪
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Development of Dendirimer phthalocyanine-incorporated micelles for photodynamic therapy2007
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  1st Asian Biomaterials Congress
- Place of Presentation
  Tsukuba
- Year and Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] トランスレーショナルリサーチの実現に向けた高分子ミセル型DDSの開発2007
- Author(s)
  西山伸宏
- Organizer
  創剤フォーラム第13回若手研究会
- Place of Presentation
  摂南大学大阪センター
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Stimuli-responsive drug and gene nanocarriers based on supramolecular assemblies2007
- Author(s)
  N. Nishiyama, K. Kataoka
- Organizer
  34th Annual Meeting & Exposition of the Controlled Release Society (CRS)
- Place of Presentation
  Long Beach, California
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 空間構造を規制した超分子形成を基盤とする光応答型ナノデバイスの創出2007
- Author(s)
  西山伸宏
- Organizer
  第56回高分子学会年次大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 高分子集合体を基盤とする薬剤・遺伝子送達キャリアの創製2007
- Author(s)
  西山伸宏
- Organizer
  ナノ学会第5回大会
- Place of Presentation
  つくば国際会議場(エポカルつくば)
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 電磁波エネルギーを利用したナノ診断・治療システムの創製の研究開発2007
- Author(s)
  西山伸宏
- Organizer
  第23回日本Drug Delivery System (DDS)学会
- Place of Presentation
  ホテル日航熊本
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 固形がんの光力学治療のためのデンドリマーフタロシアニン内包高分子ミセルの開発2007
- Author(s)
  西山伸宏
- Organizer
  第29回日本バイオマテリアル学会大会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2007-11-27
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] 固形がんの光力学治療のためのデンドリマーフタロシアニン内包高分子ミセルの開発2007
- Author(s)
  西山伸宏, 熊谷康顕, 堀江壮太, Sarma Tridib, 程域, 張祐銅, 中岸義典, 守本祐司, 片岡一則
- Organizer
  第29回日本バイオマテリアル学会大会
- Place of Presentation
  千里ライフサイエンスセンター, 大阪(口頭)
- Year and Date
  2007-11-27
- Data Source
  KAKENHI-PROJECT-19680026
[Presentation] Development of smart nanocarriers for targeting therapy2007
- Author(s)
  Nobuhiro Nishiyama
- Organizer
  2007 International Symposium on Nano-Bioscience
- Place of Presentation
  Kyung Hee University, Seoul, Korea
- Year and Date
  2007-08-20
- Data Source
  KAKENHI-PROJECT-19680026
[]
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Nishiyama Nobuhiro 西山 伸宏

NISHIYAMA Nobuhiro 西山 伸宏

西山 信宏 ニシヤマ ノブヒロ

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Development of polymeric micelles based on innovative core-shell design for various therapeutic modalitiesPrincipal Investigator

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Development of smart polymeric micelles based on novel shell and core designsPrincipal Investigator

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Design of functional polymers responsive to tumor microenvironment and their applications for diagnosis and therapyPrincipal Investigator

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深部がんのイメージングおよび標的治療を可能にする高分子ナノデバイスの創製Principal Investigator

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診断分子と治療分子を搭載したセラノスティック型ナノＤＤＳの創製Principal Investigator

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Design of functional ligand molecules focused on specific metabolism of cancer cells and their applications for diagnosis and therapyPrincipal Investigator

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Development of smart MRI contrast agents based on polymeric micelles to detect tumor microenvironmentPrincipal Investigator

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Nishiyama Nobuhiro 西山伸宏

NISHIYAMA Nobuhiro 西山伸宏

西山信宏ニシヤマノブヒロ