AONUMA Kazutaka 青沼和隆

Researcher Number	10375488
Other IDs	https://orcid.org/0000-0002-3786-0886
Affiliation (based on the past Project Information) *help	2011 – 2019: 筑波大学, 医学医療系, 教授 2010: 筑波大学, 大学院・人間総合科学研究科, 教授
Review Section/Research Field	Principal Investigator Integrative animal science / Applied pharmacology Except Principal Investigator Cardiovascular medicine / Circulatory organs internal medicine / Thoracic surgery
Keywords	Principal Investigator 遺伝子 / 疾患モデル / 心室性不整脈 / 臨床心臓学 / マウス / 遺伝性 / 突然死 / 不整脈 / 炎症反応 / 不全心筋 / 酸化ストレス / 慢性炎症 / 心不全 … More Except Principal Investigator … More 不整脈 / ロボットスーツ / 心臓リハビリテーション / 慢性心不全 / ３次元心エコー図 / 右室機能 / 三次元画像 / 心エコー図 / 右室 / 心機能 / 右心室 / スペックルトラッキング法 / 超音波 / 連続性分裂電位 / 臨床心臓学 / 心房細動 / 腎デナベーション / 交感神経 / 高血圧 / 心室不整脈 / 植込み型除細動器 / 東日本大震災 / 致死性不整脈 / トランクスクリプトーム解析 / バイオマーカー / テネイシンCノックアウトマウス / B型大動脈解離 / 心エコー図法 / 心不全 / 心臓超音波法 / 心臓再同期療法 / 臨床心血管病態学 Less

Development of the innovative treatment using a robot suit HAL in patients with refractory severe heart failure
- Principal Investigator
  
  Koike Akira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Tsukuba
Elucidation of molecular mechanisms of spontaneous sudden cardiac death model mouse due to ventricular arrhythmiaPrincipal Investigator
- Principal Investigator
  
  Aonuma Kazutaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Integrative animal science
- Research Institution
  University of Tsukuba
Mechanism of complex fractionated atrial electrograms in persistent atrial fibrillation
- Principal Investigator
  
  MURAKOSHI Nobuyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Tsukuba
RENAL DENERVATION: NOVEL THERAPY FOR RESISTANT HYPERTENSION
- Principal Investigator
  
  Sato Akira
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Tsukuba
Development of three dimensional speckle tracking echocardiography system specialized for the right ventricle
- Principal Investigator
  
  Seo Yoshihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Tsukuba
Influence of appearance of fatal arrhythmia related to the Great East Japan Earthquake Disaster
- Principal Investigator
  
  SEKIGUCHI Yukio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Tsukuba
The search for elucidating the contribution of chronic inflammation to the development of heart failure and for new treatmentPrincipal Investigator
- Principal Investigator
  
  AONUMA Kazutaka
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Tsukuba
Multicenter cohort study for usefulness of speckle tracking echocardiography to predict cardiac resynchronization therapy
- Principal Investigator
  
  SEO Yoshihiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Tsukuba
M0LECULAR MECHANISIM AND BIOMARKER OF AORTIC DISSECTION
- Principal Investigator
  
  SATO Akira
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  University of Tsukuba

All 2019 2018 2016 2015 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Effects of a lumbar-type hybrid assistive limb on cardiopulmonary burden during squat exercise in healthy subjects2019
- Author(s)
  Watanabe Hiroki、Koike Akira、Pak Yo Joon、Wu Longmei、Kubota Hiroshi、Konno Hirotomo、Sato Akira、Kawamoto Hiroaki、Matsumura Akira、Aonuma Kazutaka、Sankai Yoshiyuki、Ieda Masaki
- Journal Title
  
  Journal of Clinical Neuroscience
  
  Volume: 66 Pages: 226-230
- DOI
  10.1016/j.jocn.2019.05.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09485
[Journal Article] Efficacy of Cardiac Rehabilitation with Assistance from Hybrid Assistive Limb in Patients with Chronic Heart Failure: Protocol for a Randomized Controlled Study2019
- Author(s)
  Watanabe Hiroki、Koike Akira、Wu Longmei、Kato Hidenori、Konno Hirotomo、Sato Akira、Kawamoto Hiroaki、Matsumura Akira、Aonuma Kazutaka、Sankai Yoshiyuki、Ieda Masaki
- Journal Title
  
  Cardiology
  
  Volume: 142 Issue: 4 Pages: 213-219
- DOI
  10.1159/000500263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09485
[Journal Article] Effects of a cyborg-type robot suit HAL on cardiopulmonary burden during exercise in normal subjects2018
- Author(s)
  Pak Yo Joon、Koike Akira、Watanabe Hiroki、Terai Tomoko、Kubota Hiroshi、Takahashi Masahumi、Konno Hirotomo、Kato Jo、Nishi Isao、Sato Akira、Kawamoto Hiroaki、Aonuma Kazutaka、Ieda Masaki、Sankai Yoshiyuki
- Journal Title
  
  European Journal of Applied Physiology
  
  Volume: 119 Issue: 2 Pages: 487-493
- DOI
  10.1007/s00421-018-4040-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09485
[Journal Article] Right Ventricular Deformation Analyses Using a Three-Dimensional Speckle-Tracking Echocardiographic System Specialized for the Right Ventricle.2016
- Author(s)
  Atsumi A, Seo Y, Ishizu T, Nakamura A, Enomoto Y, Harimura Y, Okazaki T, Abe Y, Aonuma K.
- Journal Title
  
  Journal of the American Society of Echocardiography
  
  Volume: in press Issue: 5 Pages: 402-411.e2
- DOI
  10.1016/j.echo.2015.12.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461041
[Journal Article] Impacts of Surgically-Performed Renal Denervation on the Cardiovascular and Electrophysiological Variables in the Chronic Atrioventricular Block Dogs: Comparison with Those of Amiodarone2016
- Author(s)
  Wada T, Ohara H, Nakamura Y, Yokoyama H, Cao X, Izumi-Nakaseko H, Ando K, Murakoshi N, Sato A, Aonuma K, Takahara A, Nakazato Y, Sugiyama A.
- Journal Title
  
  Circ J
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461042
[Journal Article] Preliminary Study of Serum Tenascin-C Levels as a Diagnostic or Prognostic Biomarker of Type B Acute Aortic Dissection2013
- Author(s)
  Nozato T, Sato A, Hirose S, Hikita H, Takahashi A, Imanaka-Yoshida K, Yoshida T, Aonuma K, Hiroe M
- Journal Title
  
  Int J Cardiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591535
[Journal Article] Increased plasma levels of big-endothelin-2 and big-endothelin-3 in patients with end-stage renal disease2012
- Author(s)
  Miyauchi Y, Sakai S, Maeda S, Shimojo N, Watanabe S, Homma S, Kuga K, Aonuma K, Miyauchi T
- Journal Title
  
  Life Sci.
  
  Volume: 91 Pages: 729-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659279
[Journal Article] Prognostic value of serum tenascin-C levels on long-term outcome after acute myocardial infarction2012
- Author(s)
  Sato A, Hiroe M, Akiyama D, Hikita H, Nozato T, Hoshi T, Kimura T, Wang Z, Sakai S, Imanaka-Yoshida K, Yoshida T, Aonuma K
- Journal Title
  
  J Card Fail
  
  Volume: 18 Pages: 480-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659279
[Journal Article] Endothelin-1-induced cardiomyocyte hypertrophy is partly regulated by transcription factor II-F interacting C-terminal domain phosphatase of RNA polymerase II2012
- Author(s)
  Sakai S, Kimura T, Wang Z, Shimojo N, Maruyama H, Homma S, Kuga K, Yamaguchi I, Aonuma K, Miyauchi T.
- Journal Title
  
  Life Sci.
  
  Volume: 91 Pages: 572-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659279
[Journal Article] Suppressor of cytokine signaling 1 DNA administration inhibits inflammatory and pathogenic responses in autoimmune myocarditis2012
- Author(s)
  Tajiri K, Imanaka-Yoshida K, Matsubara A, Tsujimura Y, Hiroe M, Naka T, Shimojo N, Sakai S, Aonuma K, Yasutomi Y
- Journal Title
  
  J Immunol.
  
  Volume: 189 Pages: 2043-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659279
[Journal Article] Tenascin-C is expressed in abdominal aortic aneurysm tissue with an active degradation process2011
- Author(s)
  naka-Yoshida K, Yoshida T, Ikeda Y, Morikage N, Endo H, Hamano K, Imaizumi T, Hiroe M, Aonuma K, Matsuzaki M
- Journal Title
  
  Pathol Int
  
  Volume: 61(10) Pages: 559-64
- NAID
  10030721173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591535
[Journal Article] Prediction of Chronic Renal Insufficiency after Coronary Angiography by an Early Increase in Oxidative Stress and Decrease in Glomerular Filtration Rate2011
- Author(s)
  Tajiri K, Maruyama H, Sato A, Shimojo N, Endo M, Aihara H, Kawano S, Watanabe S, Sakai S, Aonuma K
- Journal Title
  
  Circ J
  
  Volume: 75 Pages: 437-442
- NAID
  10027427336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659279
[Presentation] Feasibility of Using a Lumber-type Hybrid Assistive Limb (HAL) as a Tool of Exercise Therapy in Patients with Heart Failure.2019
- Author(s)
  Wu L，Koike A，Kato H，Watanabe H，Kubota H，Boku Y，Nishi I，Sato A，Aonuma K，Ieda M.
- Organizer
  日本循環器学会
- Data Source
  KAKENHI-PROJECT-17K09485
[Presentation] Effects of hybrid assistive limb (HAL) on muscle strength in patients with heart failure2019
- Author(s)
  Kato H, Koike A, Wu L, Watanabe H, Kubota H, Konno H, Nishi I, Kawamoto H, Sato A, Matsumura A, Aonuma K, Sankai Y, Ieda M.
- Organizer
  EuroPrevent
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09485
[Presentation] Effects of a Lumbar-type HAL on Cardiopulmonary Burden during Squat Exercise in Healthy Subjects.2019
- Author(s)
  渡邉大貴，小池朗，朴要俊，呉龍梅，久保田浩，加藤秀典，佐藤明，青沼和隆，家田真樹.
- Organizer
  日本循環器学会
- Data Source
  KAKENHI-PROJECT-17K09485
[Presentation] Effects of Hybrid Assistive Limb (HAL) on Muscle Strength in Patients with Heart Failure.2019
- Author(s)
  加藤秀典，小池朗，呉龍梅，渡邉大貴，久保田浩，朴要俊，西功，佐藤明，青沼和隆，家田真樹.
- Organizer
  日本循環器学会
- Data Source
  KAKENHI-PROJECT-17K09485
[Presentation] 健常者におけるロボットスーツHALの呼吸循環系への負荷軽減効果に関する検討.2018
- Author(s)
  朴要俊，小池朗，久保田浩，渡邉大貴，高橋雅文，近野宏知，加藤穣，寺井知子，河本浩明，佐藤明，青沼和隆.
- Organizer
  日本心臓リハビリテーション学会
- Data Source
  KAKENHI-PROJECT-17K09485
[Presentation] Effects Of A Cyborg-Type Robot Hal During Squat Exercise In Healthy Subjects.2018
- Author(s)
  Watanabe H, Koike A, Pak YJ, Wu L, Kubota H, Konno H, Sato A, Matsumura A, Aonuma K, Ieda M, Sankai Y.
- Organizer
  American Heart Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09485
[Presentation] Effects of Cyborg-Type Robot Suit HAL on Cardiopulmonary Burden during Exercise in Normal Subjects2018
- Author(s)
  Boku Y, Koike A, Watanabe H, Terai T, Kubota H, Sasajima Y, Takayanagi Y, Takahashi M, Konno H, Nishi I, Kawamoto H, Sato A, Aonuma K.
- Organizer
  第82回日本循環器学会
- Data Source
  KAKENHI-PROJECT-17K09485
[Presentation] Effects of Cyborg-Type Robot Suit HAL on Cardiopulmonary Burden during Exercise in Normal Subjects.2018
- Author(s)
  Pak YJ, Koike A, Watanabe H, Terai T, Kubota H, Takayanagi Y, Takahashi M, Konno H, Nishi I, Kawamoto H, Sato A, Aonuma K.
- Organizer
  EuroPrevent
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09485
[Presentation] Clinical feasibility of a novel three-dimensional speckle tracking imaging system specialized for the right ventricle.2015
- Author(s)
  Yoshihiro Seo, Akiko Atsumi, Tomoko Ishizu, Masayoshi Yamamoto, Kazutaka Aonuma.
- Organizer
  26th Annual Scientific Sessions of the American Society of Echocardiography 2015
- Place of Presentation
  Boston (USA)
- Year and Date
  2015-06-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461041
[Presentation] Involvement of Sterol Regulatory Element Binding Protein-1 (SREBP-1) in Angiotensin II-Induced Cardiac Injury via Chronic Inflammatory Responses2012
- Author(s)
  Sakai S, Nakagawa Y, Shimojo N, Kuga K, Homma S, Shimano H, Aonuma K:
- Organizer
  第76回日本循環器学会総会・学術集会
- Place of Presentation
  福岡
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-23659279
[Presentation] Protective Activity to Oxydative Stress is Attenuated in Development of Angiotensin II-Induced Cardiac Fibrosis and Dysfunction2012
- Author(s)
  Sakai S, Warabi E, Kimura T, Miyauchi T, Aonuma K, Ishii T:
- Organizer
  The 16th Society for Free Radical Research International Biennial Meeting
- Place of Presentation
  London, UK
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-23659279
[Presentation] Sterol regulatory element-binding protein-1 is involved in the development of angiotensin II-induced cardiac fibrosis.2012
- Author(s)
  Sakai S, Nakagawa N, Shimojo N, Kumura T, Tajiri K, Kuga K, Homma S, Miyauchi T, Aonuma K, Shimano H
- Organizer
  Basic Cardiovascular Sciences Conference
- Place of Presentation
  New Orleans, USA
- Year and Date
  2012-07-24
- Data Source
  KAKENHI-PROJECT-23659279
[Presentation] Slowly Progressed Inflammatory Responses May Contribute to the Angiotensin II-Induced Cardiac Dysfunction2011
- Author(s)
  Sakai S, Nakagawa Y, Shimojo N, Yoshida K, Kimura T, Maruyama H, Honma S, Shimano H, Aonuma K
- Organizer
  第75回日本循環器学会総会・学術集会.
- Place of Presentation
  横浜
- Year and Date
  2011-08-01
- Data Source
  KAKENHI-PROJECT-23659279
[Presentation] Sterol Regulatory Element-Binding Protein-1 Participates in the Development of Cardiac Injury via Chronic Inflammation2011
- Author(s)
  Sakai S, Nakagawa Y, Shimojo N, Kuga K, Homma S, Miyauchi T, Shimano H, Aonuma K
- Organizer
  American Heart Association Scientific Sessions
- Place of Presentation
  Orland, USA
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-23659279
[Presentation] テネイシンCは大動脈解離を予防する分子的ショックアブソーバーである2011
- Author(s)
  木村泰三,吉村耕一,青木浩樹,今中恭子,吉田利通,青沼和隆,廣江道昭,今泉勉,松崎益徳
- Organizer
  第58回マトリックス研究会
- Place of Presentation
  大分
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-22591535
[Presentation] 大動脈瘤分子病態における細胞外マトリックステネイシンCの役割の解明2010
- Author(s)
  木村泰三,佐藤明,青沼和隆
- Organizer
  第5回高血圧と冠動脈疾患研究会
- Place of Presentation
  東京
- Year and Date
  2010-12-25
- Data Source
  KAKENHI-PROJECT-22591535

1. SATO Akira (30528469)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. MURAKOSHI Nobuyuki (80447218)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. SEO Yoshihiro (40375499)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. ISHIZU Tomoko (10507859)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. IMANAKA Kyoko (00242967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YOSHIMURA Koichi (00322248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. KIMURA Taizo (00636508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. SAKAI Satoshi (30282362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. SHIMANO Hitoshi (20251241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. MARUYAMA Hidekazu (30528493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. SEKIGUCHI Yukio (90447251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KANESHIRO Takashi (40548913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SUGIYAMA Atsushi (60242632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. TAKAHARA Akira (80377481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. XU Dongzhu (20616651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NOGAMI Akihiko (80708602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Koike Akira (60234655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
18. 五十嵐都 (20633126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 入鹿山容子 (90312834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 呉林なごみ (50133335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 柳沢正史 (20202369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 河本浩明 (00400713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
23. 呉龍梅 (60793528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
24. 渡邉大貴 (00779572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
25. Machino Takeshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. YAMAGAMI Fumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. FENG Duo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 吉田恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

AONUMA Kazutaka 青沼 和隆

Research Projects

Research Products

Co-Researchers

Development of the innovative treatment using a robot suit HAL in patients with refractory severe heart failure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of molecular mechanisms of spontaneous sudden cardiac death model mouse due to ventricular arrhythmiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of complex fractionated atrial electrograms in persistent atrial fibrillation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

RENAL DENERVATION: NOVEL THERAPY FOR RESISTANT HYPERTENSION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of three dimensional speckle tracking echocardiography system specialized for the right ventricle

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Influence of appearance of fatal arrhythmia related to the Great East Japan Earthquake Disaster

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The search for elucidating the contribution of chronic inflammation to the development of heart failure and for new treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Multicenter cohort study for usefulness of speckle tracking echocardiography to predict cardiac resynchronization therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

M0LECULAR MECHANISIM AND BIOMARKER OF AORTIC DISSECTION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effects of a lumbar-type hybrid assistive limb on cardiopulmonary burden during squat exercise in healthy subjects2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of Cardiac Rehabilitation with Assistance from Hybrid Assistive Limb in Patients with Chronic Heart Failure: Protocol for a Randomized Controlled Study2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of a cyborg-type robot suit HAL on cardiopulmonary burden during exercise in normal subjects2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Right Ventricular Deformation Analyses Using a Three-Dimensional Speckle-Tracking Echocardiographic System Specialized for the Right Ventricle.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impacts of Surgically-Performed Renal Denervation on the Cardiovascular and Electrophysiological Variables in the Chronic Atrioventricular Block Dogs: Comparison with Those of Amiodarone2016

Author(s)

AONUMA Kazutaka 青沼和隆