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kawamura yuki  河村 由紀

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KAWAMURA Yuki  河村 由紀

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Researcher Number 10392391
Other IDs
Affiliation (Current) 2025: 国立健康危機管理研究機構, 国立国際医療研究所, 室長
Affiliation (based on the past Project Information) *help 2025: 国立研究開発法人国立国際医療研究センター, 研究所, 臨床連携研究室 室長
2023: 国立研究開発法人国立国際医療研究センター, 研究所, 臨床連携研究室 室長
2018 – 2023: 国立研究開発法人国立国際医療研究センター, その他部局等, 消化器病態生理研究室長
2022: 国立研究開発法人国立国際医療研究センター, その他部局等, 共通実験室長
2021: 国立研究開発法人国立国際医療研究センター, その他部局等, 室長 … More
2017: 国立研究開発法人国立国際医療研究センター, その他, 消化器病態生理研究室長
2017: 国立研究開発法人国立国際医療研究センター, 消化器疾患研究部, 消化器病態生理研究室長
2016: 国立研究開発法人国立国際医療研究センター, その他部局等, 消化器病態生理研究室長
2015: 国立研究開発法人国立国際医療研究センター, 研究所・肝炎・免疫研究センター・消化器疾患研究部, 消化器病態生理研究室長
2014: 独立行政法人国立国際医療研究センター, その他部局等, 室長
2013: 国立国際医療研究センター研究所肝炎・免疫研究センター, 消化器疾患研究部, 病態生理研究研究室長・室長
2013: 独立行政法人国立国際医療研究センター, その他部局等, 消化器病態生理研究室長
2012: 独立行政法人国立国際医療研究センター, その他部局等, その他
2012: 独立行政法人国立国際医療研究センター, 肝炎・免疫研究センター・消化器疾患研究部・消化器病態生理研究室, 室長
2011: 独立行政法人国立国際医療研究センター, 研究所・肝炎・免疫研究センター・消化器疾患研究部・消化器病態生理研究室, 室長
2010: 独立行政法人国立国際医療研究センター, 研究所肝炎・免疫研究センター消化器疾患研究部・消化器病態生理研究室, 室長
2009: 独立行政法人国立国際医療研究センター
2005 – 2008: 国立国際医療センター(研究所), 消化器疾患研究部, 研究員
2007: 国立国際医療センター(研究所), 消化器研究部, 協力研究員
2006 – 2007: 国立国際医療センター(研究所), 協力研究員 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 53030:Respiratory medicine-related / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Basic Section 53010:Gastroenterology-related / Digestive surgery / Gastroenterology / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Biological Sciences
Keywords
Principal Investigator
消化管 / 幹細胞 / エピゲノム / 糖鎖 / 肺胞 / 気管支 / /幹細胞 / 食道扁平上皮 / 食道-胃接合部 / 食道ー胃接合部 … More / 癌 / 食道ー胃接合部癌 / エピジェネティクス / 炎症性腸疾患 / 下部消化管学(小腸、大腸) / レクチン / 糖類 / マクロファージ / リポ多糖 / 低免疫応答 … More
Except Principal Investigator
腸内細菌 / 癌 / 消化管上皮細胞 / 腸肺相関 / RSウイルス / 経口免疫寛容 / 絶食応答 / 骨髄 / パイエル板 / 腸ー骨髄連関 / 経口寛容 / 栄養シグナル / 腸管免疫 / 腸内細菌代謝産物 / アクアポリン / ディフェンシン / 抗菌 / T-RFLP法 / 腸内細菌叢 / 糞便 / IgA / ヒスタミンH2受容体 / H2ブロッカー / 粘膜防御 / NSAIDs / ムチン / 腹膜播種 / 外科 / 化学放射線療法 / 食道扁平上皮癌 / TNFSP / レトロトランスポジション / TNFSF / 消化管炎症 / 炎症 / DNA傷害 / Fn14 / TWEAK / 上皮細胞 / アポトーシス / IL-4 / IL-13 / Sd^a血液型糖鎖 / 大腸がん / 胃がん / 潰瘍性大腸炎 / Sd^a血液型 / 大腸癌 / 胃癌 / 糖転移酵素 / DNAメチル化 Less
  • Research Projects

    (16 results)
  • Research Products

    (164 results)
  • Co-Researchers

    (21 People)
  •  脂肪酸結合タンパク質FABP5を介した肺胞上皮再生機構の解明Principal Investigator

    • Principal Investigator
      河村 由紀
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      National Center for Global Health and Medicine
  •  乳幼児RSウイルス感染予防に向けた腸管を主眼とする新たな試み

    • Principal Investigator
      川島 麗
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kitasato University
  •  気管支上皮および肺胞上皮幹細胞特異的に発現する新規分子の機能解析Principal Investigator

    • Principal Investigator
      河村 由紀
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      National Center for Global Health and Medicine
  •  Association of water-retaining mucins with metabolites derived from the intestinal microbiota

    • Principal Investigator
      Ichikawa Takafumi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kitasato University
  •  Starvation response of the immune system along the gut-bone marrow axis

    • Principal Investigator
      Hase Koji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Keio University
  •  Molecular functions of a novel gene exclusively expressed in esophageal basal cellsPrincipal Investigator

    • Principal Investigator
      Kawamura Yuki I.
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      National Center for Global Health and Medicine
  •  腹膜播種成立に関与する腹腔内環境と免疫チェックポイント

    • Principal Investigator
      相馬 大介
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      National Center for Global Health and Medicine
  •  Helicobacter pylori infection-independent adenocarcinomas of the gastroesophageal junction and gastric corpusPrincipal Investigator

    • Principal Investigator
      KAWAMURA Yuki I.
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Center for Global Health and Medicine
  •  Epigenetic alterations related to efficacy of neoadjuvant therapy before esophagectomy

    • Principal Investigator
      Yamada Kazuhiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      National Center for Global Health and Medicine
  •  Epigenetic dysregulation of immune responses in inflammatory bowel diseasePrincipal Investigator

    • Principal Investigator
      Kawamura Yuki I.
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Center for Global Health and Medicine
  •  TWEAK is involved in DNA damage in intestinal epithelial cells

    • Principal Investigator
      DOHI Taeko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  Epigenetically regulated tissue repair mechanism in gastrointestinal tractPrincipal Investigator

    • Principal Investigator
      KAWAMURA I. Yuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  T helper 2 type cytokines in the gastrointestinal tissue injury

    • Principal Investigator
      DOHI Taeko
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  Study to find lectins, ligands for Sd^a carbohydrate antigen,which is normally expressed in gastrointestinal tractPrincipal Investigator

    • Principal Investigator
      KAWAMURA I Yuki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  DNAメチル化による糖転移酵素遺伝子不活化の、炎症発がん・がんの進展における意義

    • Principal Investigator
      DOHI Taeko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  消化管微小環境による炎症応答抑制機構の分子生物学的解析Principal Investigator

    • Principal Investigator
      河村 由紀
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Research Institute, International Medical Center of Japan

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation

  • [Journal Article] Kallikrein-related peptidase 13 expression and clinicopathological features in lung squamous cell carcinoma2023

    • Author(s)
      Sumiya Ryusuke、Yamada Kazuhiko、Hagiwara Teruki、Nagasaka Satoshi、Miyazaki Hideki、Igari Toru、Kawamura Yuki
    • Journal Title

      Molecular and Clinical Oncology

      Volume: 19 Issue: 2

    • DOI

      10.3892/mco.2023.2660

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15564, KAKENHI-PROJECT-22K08273
  • [Journal Article] Novel protocol to observe the intestinal tuft cell using transmission electron microscopy2022

    • Author(s)
      Kozono Takuma、Tamura-Nakano Miwa、Kawamura Yuki I.、Tonozuka Takashi、Nishikawa Atsushi
    • Journal Title

      Biology Open

      Volume: 11 Issue: 2

    • DOI

      10.1242/bio.059007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K14801, KAKENHI-PROJECT-22K08273
  • [Journal Article] Loss of GSTO2 contributes to cell growth and mitochondria function via the p38 signaling in lung squamous cell carcinoma2021

    • Author(s)
      Sumiya Ryusuke、Terayama Masayoshi、Hagiwara Teruki、Nakata Kazuaki、Sekihara Keigo、Nagasaka Satoshi、Miyazaki Hideki、Igari Toru、Yamada Kazuhiko、Kawamura Yuki I.
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 1 Pages: 195-204

    • DOI

      10.1111/cas.15189

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08457, KAKENHI-PROJECT-20K17007
  • [Journal Article] Expression status of serine protease 27: A prognostic marker for esophageal squamous cell carcinoma treated with preoperative chemotherapy/chemoradiotherapy2021

    • Author(s)
      Kataoka, A, Yamada K, Hagiwara T, Terayama M, Sugimoto T, Nohara K, Igari T, Yokoi C, Kawamura YI.
    • Journal Title

      Annals of Surgical Oncology

      Volume: 印刷中 Issue: 9 Pages: 5373-5381

    • DOI

      10.1245/s10434-020-09550-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08457, KAKENHI-PROJECT-19K24058
  • [Journal Article] ASO Author Reflections: Serine Protease 27 is a Novel Prognostic Indicator for Esophageal Squamous Cell Carcinoma with Preoperative Treatment2021

    • Author(s)
      Kataoka Atsuko、Yamada Kazuhiko、Kawamura Yuki I.
    • Journal Title

      Annals of Surgical Oncology

      Volume: 28 Issue: 9 Pages: 5382-5383

    • DOI

      10.1245/s10434-020-09580-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08457
  • [Journal Article] The N-terminal region of Jaw1 has a role to inhibit the formation of organized smooth endoplasmic reticulum as an intrinsically disordered region2021

    • Author(s)
      Kozono T, Sato H, Okumura W, Jogano C, Tamura-Nakano M, Kawamura YI, Rohrer J, Tonozuka, T, Nishikawa A.
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 753-753

    • DOI

      10.1038/s41598-020-80258-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08457, KAKENHI-PROJECT-18K06107
  • [Journal Article] Glutathione S-transferase Omega 2 Regulates Cell Growth and the Expression of E-cadherin via Post-Transcriptional Downregulation of β-Catenin in Human Esophageal Squamous Cells2019

    • Author(s)
      Terayama M, Yamada K, Hagiwara T, Inazuka F, Sezaki T, Igari T, Yokoi C, Nohara K, Soma D, Dohi T, Kawamura YI.
    • Journal Title

      Carcinogenesis

      Volume: 印刷中 Issue: 7 Pages: 875-886

    • DOI

      10.1093/carcin/bgz189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08457, KAKENHI-PROJECT-19K24058
  • [Journal Article] Expression of the desmosome-related molecule periplakin is associated with advanced stage and poor prognosis of esophageal squamous cell carcinoma.2018

    • Author(s)
      Yamada K, Hagiwara T, Inazuka F, Sezaki T, Igari T, Yokoi C, Nohara K, Yamashita S, Dohi T, Kawamura YI.
    • Journal Title

      Transl Cancer Res

      Volume: 7 Pages: 79-87

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Journal Article] Expression of the desmosome-related molecule periplakin is associated with advanced stage and poor prognosis of esophageal squamous cell carcinoma.2018

    • Author(s)
      Yamada K, Hagiwara T, Inazuka F, Sezaki T, Igari T, Yokoi C, Nohara K, Yamashita S, Dohi T, Kawamura YI.
    • Journal Title

      Translational Cancer Research

      Volume: 7 Issue: 1 Pages: 79-87

    • DOI

      10.21037/tcr.2018.01.03

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Journal Article] Expression of kallikrein-related peptidase 13 is associated with poor prognosis in esophageal squamous cell carcinoma.2018

    • Author(s)
      Nohara K, Yamada K, Yamada L, Hagiwara T, Igari T, Yokoi C, Som, D, Yamashita S, Dohi T, Kawamura YI.
    • Journal Title

      General Thoracic Cardiovascular Surgery

      Volume: 66 Issue: 6 Pages: 79-87

    • DOI

      10.1007/s11748-018-0923-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Journal Article] Expression of kallikrein-related peptidase 13 is associated with poor prognosis in esophageal squamous cell carcinoma2018

    • Author(s)
      Nohara Kyoko、Yamada Kazuhiko、Yamada Leo、Hagiwara Teruki、Igari Toru、Yokoi Chizu、Soma Daisuke、Yamashita Satoshi、Dohi Taeko、Kawamura Yuki I.
    • Journal Title

      General Thoracic and Cardiovascular Surgery

      Volume: 66 Issue: 6 Pages: 351-357

    • DOI

      10.1007/s11748-018-0910-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10618
  • [Journal Article] Expression of kvllikrein-related peptidase 13 is associated with poor prognosis in esophageal squamous cell carcinoma.2018

    • Author(s)
      Nohara K, Yamada K, Yamada L, Hagiwara T, Igari T, Yokoi C, Soma D, Yamashita S, Dohi T, Kawamura YI.
    • Journal Title

      Gen Thorac Cardiovasc Surg

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10618
  • [Journal Article] Sarcopenia, the depletion of muscle mass, an independent predictor of respiratory complications after oncological esophagectomy2018

    • Author(s)
      Soma D、Kawamura Y I、Yamashita S、Wake H、Nohara K、Yamada K、Kokudo N
    • Journal Title

      Diseases of the Esophagus

      Volume: 32 Issue: 3

    • DOI

      10.1093/dote/doy092

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10618
  • [Journal Article] Clinicopathological significance of cystatin A expression in progression of esophageal squamous cell carcinoma.2018

    • Author(s)
      Shiba D, Terayama M, Yamada K, Hagiwara T, Oyama C, Tamura-Nakano M, Igari T, Yokoi C, Soma D, Nohara K, Yamashita S, Dohi T, Kawamura YI.
    • Journal Title

      Medicine

      Volume: 97 Issue: 15 Pages: e0357-e0357

    • DOI

      10.1097/md.0000000000010357

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09299, KAKENHI-PROJECT-17K10618
  • [Journal Article] DNA Hypermethylation and silencing of PITX1 correlated with advanced stage and poor postoperative prognosis of esophageal squamous cell carcinoma2017

    • Author(s)
      Otsubo T, Yamada K, Hagiwara T, Oshima K, Iida K, Nishikata K, Toyoda T, Igari T, Nohara K, Yamashita S, Hattori M, Dohi T and Kawamura YI.
    • Journal Title

      Ongotarget

      Volume: 8 Issue: 48 Pages: 84434-84448

    • DOI

      10.18632/oncotarget.21375

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04503, KAKENHI-PROJECT-15K10124
  • [Journal Article] DNA hypermethylation and silencing of PITX1 correlated with advanced stage and poor postoperative prognosis of esophageal squamous cell carcinoma.2017

    • Author(s)
      Otsubo T, Yamada K, Hagiwara T, Oshima K, Iida K, Nishikata K, Toyoda T, Igari T, Nohara K, Yamashita S, Hattori M, Dohi T, Kawamura YI.
    • Journal Title

      Oncotarget

      Volume: 8 Pages: 84434-84448

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Journal Article] Fatty acids in a high-fat diet potentially induce gastric parietal-cell damage and metaplasia in mice2016

    • Author(s)
      Hirata, Y. Sezaki, T. Tamura-Nakano, M. Oyama, C. Hagiwara, T. Ishikawa, T. Fukuda, S. Yamada, K. Higuchi, K. Dohi, T. Kawamura, Y. I.
    • Journal Title

      J Gastroenterol

      Volume: - Issue: 8 Pages: 889-903

    • DOI

      10.1007/s00535-016-1291-0

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04503, KAKENHI-PROJECT-15K10124, KAKENHI-PROJECT-16K09299
  • [Journal Article] Interferon-gamma Constrains Cytokine Production of Group 2 Innate Lymphoid Cells2016

    • Author(s)
      Kudo, F. Ikutani, M. Seki, Y. Otsubo, T. Kawamura, Y. I. Dohi, T. Oshima, K. Hattori, M. Nakae, S. Takatsu, K. Takaki, S.
    • Journal Title

      Immunology

      Volume: 147 Issue: 1 Pages: 21-29

    • DOI

      10.1111/imm.12537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04503, KAKENHI-PROJECT-25460965, KAKENHI-PROJECT-25293097
  • [Journal Article] Retrotransposition of long interspersed nucleotide element-1 is associated with colitis but not tumors in a murine colitic cancer model.2015

    • Author(s)
      Otsubo T, Okamura T, Hagiwara T, Ishizaka Y, Dohi T, Kawamura YI.
    • Journal Title

      PLoS One

      Volume: 10 (2) Issue: 2 Pages: e0116072-e0116072

    • DOI

      10.1371/journal.pone.0116072

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460965
  • [Journal Article] Aberrant DNA hypermethylation reduces the expression of the desmosome-related molecule periplakin in esophageal squamous cell carcinoma2015

    • Author(s)
      Otsubo T, Hagiwara T, Tamura-Nakano M, Sezaki T, Miyake O, Hinohara C, Shimizu T, Yamada K, Dohi T, Kawamura YI.
    • Journal Title

      Cancer Medicine

      Volume: 4 Issue: 3 Pages: 415-425

    • DOI

      10.1002/cam4.369

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Journal Article] The epigenetic regulator Uhrf1 facilitates proliferation and maturation of colonic regulatory T cells2014

    • Author(s)
      Yuuki Obata*, Yukihiro Furusawa*, Takaho A. Endo, Jafar Sharif, Daisuke Takahashi, Koji Atarashi, Manabu Nakayama, Satoshi Onawa, Yumiko Fujimura, Masumi Takahashi, Tomokatsu Ikawa, Takeshi Otsubo, Yuki I. Kawamura, Taeko Dohi, Shoji Tajima, Osamu Ohara, Kenya Honda, Shohei Hori, Hiroshi Ohno, Haruhiko Koseki and Koji Hase. 【* : 筆頭筆者】
    • Journal Title

      Nature Immunology

      Volume: 15 Issue: 6 Pages: 571-579

    • DOI

      10.1038/ni.2886

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J02667, KAKENHI-PLANNED-23114008, KAKENHI-PROJECT-23247030, KAKENHI-PROJECT-23249015, KAKENHI-PUBLICLY-24117723, KAKENHI-PROJECT-24689042, KAKENHI-PROJECT-24890293, KAKENHI-PUBLICLY-25118732, KAKENHI-PUBLICLY-25118733, KAKENHI-PROJECT-25291025, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25460965, KAKENHI-PUBLICLY-26116709, KAKENHI-PROJECT-26293229, KAKENHI-PROJECT-26670472
  • [Journal Article] Enhancement of leptin receptor signaling by SOCS3 deficiency induces development of gastric tumors in mice.2014

    • Author(s)
      Inagaki-Ohara K, Mayuzumi H, Kato S, Minokoshi Y, Otsubo T, Kawamura YI, Dohi T, Matsuzaki G, Yoshimura A.
    • Journal Title

      Oncogene

      Volume: 33 Issue: 1 Pages: 74-84

    • DOI

      10.1038/onc.2012.540

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22126005, KAKENHI-PROJECT-23590272, KAKENHI-PROJECT-23590955, KAKENHI-PROJECT-24390058
  • [Journal Article] Retrotransposition of long interspersed element-1 by viral protein R of human immunodeficiency virus type-12013

    • Author(s)
      Kenta Iijima, Noriyuki Okudaira, Masato Tamura, Akihiro Doi, Yoshikazu Saito, Mari Shimura, Motohito Goto, Akihiro Matsunaga, Yuki Kawamura, Takeshi Otsubo, Taeko Dohi, Shigeki Hoshino, Shigeyuki Kano, Shotaro Hagiwara, Junko Tanuma, Hiroyuki Gatanaga, Masanori Baba, Taku Iguchi, Motoko Yanagita, Shin-ichi Oka Tadashi Okamura and Yukihito Ishizaka
    • Journal Title

      Retrovirology

      Volume: 10 Issue: 1 Pages: 83-83

    • DOI

      10.1186/1742-4690-10-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J10677, KAKENHI-PROJECT-23590955
  • [Journal Article] TWEAK/Fn14 pathway promotes a T helper 2-type chronic colitis with fibrosis in mice2013

    • Author(s)
      Son A, Oshio T, Kawamura YI, Hagiwara T, Yamazaki M, Inagaki-Ohara K, Okada T, Wu P, Iseki M, Takaki S, Burkly LC, Dohi T
    • Journal Title

      Mucosal Immunology

      Volume: 6 Issue: 6 Pages: 1131-1142

    • DOI

      10.1038/mi.2013.10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590955, KAKENHI-PROJECT-25293097
  • [Journal Article] Microbiota-derived lactate accelerates colon epithelial cell turnover in starvation-refed mice2013

    • Author(s)
      Okada T
    • Journal Title

      Nat. Commun

      Volume: 4巻 Issue: 1 Pages: 1654-1654

    • DOI

      10.1038/ncomms2668

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689017, KAKENHI-PROJECT-23590272, KAKENHI-PROJECT-23590955, KAKENHI-PROJECT-24380072, KAKENHI-PROJECT-24658129, KAKENHI-PROJECT-24700455, KAKENHI-PUBLICLY-24117524, KAKENHI-PUBLICLY-24117723
  • [Journal Article] Colonic epithelial cells express specific ligands for mucosal macrophage immunosuppressive receptors, siglec-7 and-92012

    • Author(s)
      Miyazaki, K., Sakuma, K., Kawamura, Y. I., Izawa, M., Ohmori, K., Mitsuki, M., Yamaji, T., Hashimoto, Y., Suzuki, A., Saito, Y., Dohi, T., and Kannagi, R.
    • Journal Title

      J. Immunol

      Volume: 188 Issue: 9 Pages: 4690-4700

    • DOI

      10.4049/jimmunol.1100605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590324, KAKENHI-PROJECT-22590712, KAKENHI-PROJECT-22790774, KAKENHI-PUBLICLY-23112520, KAKENHI-PROJECT-23590955, KAKENHI-PROJECT-23770164
  • [Journal Article] The monoclonal antibody HCM31 specifically recognizes the Sd^a tetrasaccharide in goblet cell mucin2012

    • Author(s)
      Tsubokawa D、Goso Y、Kawashima R、Ota H、Nakamura T、Nakamura K、Sato N、Kurihara M、Dohi T、Kawamura YI、Ichikawa T、Ishihara K
    • Journal Title

      FEBS Open Bio

      Volume: 2 Pages: 223-233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] Colonic epithelial cells express specific ligands for macrophage immunosuppressive receptors Siglec-7 and -92012

    • Author(s)
      Miyazaki K、Sakuma K、Kawamura YI、Izawa M、Ohmori K、Mitsuki M、Yamaji T、Hashimoto Y、Suzuki A、Saito Y、Dohi T、Kannagi R
    • Journal Title

      J Immunol

      Volume: 188(9) Pages: 4690-4700

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] Comprehensive analysis of chemokines and cytokines secreted in the peritoneal cavity during laparotomy2012

    • Author(s)
      Kawashima R, Kawamura YI, Oshio T, Mizutani N, Okada T, Kawamura YJ, Konishi F, Dohi T
    • Journal Title

      J Immunoassay Immunochem

      Volume: 33 Issue: 3 Pages: 291-301

    • DOI

      10.1080/15321819.2011.638409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590712, KAKENHI-PROJECT-23590955, KAKENHI-PROJECT-23790808
  • [Journal Article] 潰瘍性大腸炎と糖鎖不全現象炎症性腸疾患-病因解明と診断・治療の最新知見-XII.特論2012

    • Author(s)
      河村由紀、土肥多恵子
    • Journal Title

      日本臨床

      Volume: 70 Pages: 646-650

    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] The monoclonal antibody HCM31 specifically recognizes the Sda tetrasaccharide in goblet cell mucin2012

    • Author(s)
      Tsubokawa D, Goso Y, Kawashima R, Ota H, Nakamura T, Nakamura K, Sato N, Kurihara M, Dohi T, Kawamura YI, Ichikawa T, Ishihara K
    • Journal Title

      FEBS Open Bio

      Volume: 2 Issue: 1 Pages: 223-233

    • DOI

      10.1016/j.fob.2012.07.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] Comprehensive analysis of chemokines and cytokines secreted in the peritoneal cavity during laparotomy2012

    • Author(s)
      Kawashima R、Kawamura YI、Oshio T、Mizutani N、Okada T、Kawamura YJ、Konishi F、Dohi T
    • Journal Title

      Immunoassay Immunochem

      Volume: 33(3) Pages: 291-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] Incomplete synthesis of carbohydrate determnants in ulcerative colitis2012

    • Author(s)
      Kawamura YI, Dohi T
    • Journal Title

      Nihon Rinsho

      Volume: 70 Pages: 646-650

    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] Incomplete synthesis of carbohydrate determinants in ulcerative colitis2012

    • Author(s)
      Kawamura YI、Dohi T
    • Journal Title

      Nihon Rinsho

      Volume: 70(1) Pages: 646-650

    • NAID

      40019203412

    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] Interleukin-13 Damages Intestinal Mucosa via TWEAK and Fn14 in Mice - a Pathway Associated with Ulcerative Colitis2011

    • Author(s)
      Kawashima R, Kawamura YI, Oshio T, Son A, Yamazaki M, Hagiwara T, Okada T, Inagaki-Ohara K, Wu P, Szak S, Kawamura YJ, Konishi F, Miyake O, Yano H, Saito Y, Burkly LC, Dohi T
    • Journal Title

      Gastroenterology

      Volume: 141 Issue: 6 Pages: 2119-2129

    • DOI

      10.1053/j.gastro.2011.08.040

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590955, KAKENHI-PROJECT-23790808
  • [Journal Article] Interleukin-13 damages intestinal mucosa via TWEAK and Fn14 in mice-A pathway associated with ulcerative colitis2011

    • Author(s)
      Kawashina R, Kawamura YI, Oshio T, Son A, Yamazaki M, Hagiwara T, Okada T, Inagaki-Ohara K, Eu P, Szak S, Kawamura YJ, Konishi F, Miyake O, Yano H, Saito Y, Burkly LC, Dohi T
    • Journal Title

      Gastroenterology

      Volume: 141 Pages: 2119-2129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] The epithelia-specific membrane trafficking factor AP-1B secures gut immune homeostasis in mice2011

    • Author(s)
      Takahashi D、Hase K、Kimura S、Nakatsu F、Ohmae M、Mandai Y、Sato T、Date Y、Ebisawa M、Kato T、Obata Y、Kawamura YI、Dohi T、Katsuno T、Yokosuka O、Waguri S、Ohno H
    • Journal Title

      Gastroenterology

      Volume: 141(2) Pages: 621-632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] Interleukin-13 damages intestinal mucosa via TWEAK and Fn14 in mice - A pathway associated with ulcerative colitis2011

    • Author(s)
      Kawashima R、Kawamura YI、Oshio T、Son A、Yamazaki M、Hagiwara T、Okada T、Inagaki-Ohara K、Eu P、Szak S、Kawamura YJ、Konishi F、Miyake O、Yano H、Saito Y、Burkly LC、Dohi T
    • Journal Title

      Gastroenterology

      Volume: 141(6) Pages: 2119-2129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] The epithelia-specific membrane trafficking factor AP-1B secures gut immune homeostasis in mice2011

    • Author(s)
      Takahashi D, Hase K, Kimura S, Nakatsu F, Ohmae M, Mandai Y, Sato T, Date Y, Ebisawa M, Kato T, Obata Y, Kawamura YI, Dohi T, Katsuno T, Yokosuka O, Waguri S, Ohno H
    • Journal Title

      Gastroenterology

      Volume: 141 Pages: 621-632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] 炎症-発癌と糖鎖不全現象2010

    • Author(s)
      河村由紀
    • Journal Title

      大腸癌フロンティア

      Volume: 3(3) Pages: 214-218

    • Data Source
      KAKENHI-PROJECT-22590712
  • [Journal Article] 消化管癌における糖鎖不全現象のメカニズムとしてのDNA高メチル化2009

    • Author(s)
      河村由紀、豊田実、土肥多恵子
    • Journal Title

      分子消化器病 6(1)

      Pages: 99-101

    • Data Source
      KAKENHI-PROJECT-19790504
  • [Journal Article] COBRA法を用いたDNAメチル化検出2009

    • Author(s)
      河村由紀
    • Journal Title

      THE LUNG perspectives、分子生物学basic techniqueその54 17(1)

      Pages: 92-94

    • Data Source
      KAKENHI-PROJECT-19790504
  • [Journal Article] DNAhypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer2008

    • Author(s)
      Y.I. Kawamura
    • Journal Title

      Gastroenterology (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Journal Article] Incomplete synthes0is of the Sd(a)/Cad blood group carbohydrate in gastrointestinal cancer.2008

    • Author(s)
      Dohi T, Kawamura YI
    • Journal Title

      Biochim Biophys Ada 1780

      Pages: 467-471

    • Data Source
      KAKENHI-PROJECT-19390204
  • [Journal Article] 消化器癌の糖鎖不全現象とエピジェネティックな遺伝子発現制御2008

    • Author(s)
      土肥多恵子、河村由紀
    • Journal Title

      医学のあゆみ 225(8)

      Pages: 660-664

    • Data Source
      KAKENHI-PROJECT-19790504
  • [Journal Article] DAN hypermethylation contributes incomplete synthesis of carbo hydrate determinants in gastrointestinal cancer.2008

    • Author(s)
      河村 由紀
    • Journal Title

      Gastroenterology 135・1

      Pages: 142-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Journal Article] Incomplete synthesis of the Sda/Cad blood group carbohydrate in gastrointestinal cancer2008

    • Author(s)
      Dohi T、Kawamura YI
    • Journal Title

      Biochim. Biophys. Acta 1780(3)

      Pages: 467-471

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Journal Article] 消化管のがん性変化に伴い消失する血液型抗原Sda糖鎖2008

    • Author(s)
      河村由紀
    • Journal Title

      生化学 80(5)

      Pages: 425-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Journal Article] DNA hypermethylation contributes incomplete synthesis of carbohydrate determinants in gastrointestinal cancer2008

    • Author(s)
      Kawamura YI、Toyota M、Kawashima R、Hagiwara T、Suzuki H、Imai K、Shinomura Y、Tokino T、Kannagi R、Dohi T
    • Journal Title

      Gastroenterology 135(1)

      Pages: 142-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Journal Article] DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer2008

    • Author(s)
      Y. I. Kawamura
    • Journal Title

      Gastroenterology (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18012053
  • [Journal Article] DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer2008

    • Author(s)
      Kawamura, YI, Toyota M, Kawashima R, Hagiwara T, Suzuki H, Imai K, Shinomura Y, Tokino T, Kannagi R, Dohi T
    • Journal Title

      Gastroenterology 135

      Pages: 142-151

    • Data Source
      KAKENHI-PROJECT-19390204
  • [Journal Article] DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer2008

    • Author(s)
      Y. I. Kawamura
    • Journal Title

      Gastroenterology 135

      Pages: 142-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Journal Article] Dose-dependent, differential regulation of cytokine secretion from macrophages by fractalkine.2007

    • Author(s)
      Mizutani N, Sakurai T, Shibata T, Uchida K, Fujita J, Kawashima R, Kawamura Y.I., Toyama-Sorimachi N, Imai T, Dohi T.
    • Journal Title

      J. Immunol 79

      Pages: 7478-7487

    • Data Source
      KAKENHI-PROJECT-19390204
  • [Journal Article] Dose-dependent differential regulation of cytokine secretion from macrophages by fractalkine2007

    • Author(s)
      Mizutani N、Sakurai T、Shibata T、Uchida K、Fujita J、Kawashima R、Kawamura YI、Toyama-Sorimachi N、Imai T、Dohi T
    • Journal Title

      J immunol 179(11)

      Pages: 7478-7487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Journal Article] Inhibition of CCL1-CCR8 interaction prevents aggregation of macrophages and development of peritoneal adhesions2007

    • Author(s)
      Hoshino A、Kawamura YI、Yasuhara M、Toyama-Sorimachi N、Yamamoto K、Matsukawa, A、Lira SA、Dohi T
    • Journal Title

      J immunol 179(8)

      Pages: 5296-5304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Journal Article] Introduction of Sd^a carbohydrate antigen in gastrointestinal cancer cells eliminates selectin ligands and inhibits metastasis2005

    • Author(s)
      河村 由紀
    • Journal Title

      Cancer Research 65・14

      Pages: 3205-3212

    • Data Source
      KAKENHI-PROJECT-17790474
  • [Presentation] 腹膜播種の温熱治療効果に対する腹腔内環境への関与2023

    • Author(s)
      玉木 竣, 川島 麗, 河村 由紀, 前川 達則, 川上 文貴, 市川 尊文
    • Organizer
      第41回サイトプロテクション研究会
    • Data Source
      KAKENHI-PROJECT-20K08294
  • [Presentation] 腹膜播種の温熱治療効果に対する腹腔内環境への関与2023

    • Author(s)
      玉木 竣, 川島 麗, 河村 由紀, 前川 達則, 川上 文貴, 市川 尊文
    • Organizer
      第41回サイトプロテクション研究会
    • Data Source
      KAKENHI-PROJECT-22K07993
  • [Presentation] Smoking silenced glutathione S-transferase omega 2 (GSTO2) in lung club cells, inducing cellular senescence2023

    • Author(s)
      波多野 裕斗、住谷 隆輔、山田 和彦、國土 典宏、河村 由紀.
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-22K08273
  • [Presentation] Prognostic significance of glutathione S-Transferase omega 2, as a post-transcriptional regulator of PD-L1 in patients with lung adenocarcinoma2023

    • Author(s)
      住谷 隆輔、波多野 裕斗、山田 和彦、國土 典宏、河村 由紀.
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-22K08273
  • [Presentation] Loss of glutathione S-transferase is associated with PD-L1 expression and poor prognosis in lung adenocarcinoma2023

    • Author(s)
      Sumiya R, Hatano H, Hagiwara T, Nagasaka S, Yamada K, Kokudo N, Suzuki H, Kawamura YI.
    • Organizer
      American Association for Cancer Research Annual Meeting (米国癌学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08273
  • [Presentation] Loss of glutathione S-transferase omega 2 (GSTO2) predicts poor disease-free survival of lung adenocarcinoma2022

    • Author(s)
      波多野 裕斗、住谷 隆輔、山田 和彦、國土 典宏、河村 由紀.
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-22K08273
  • [Presentation] GSTO2, a novel tumor suppressor gene of lung squamous cell carcinoma, regulates mitochondria function via the p38/β-catenin signaling pathway2022

    • Author(s)
      Sumiya R, Terayama M, Hagiwara T, Nakata K, Nagasaka S, Yamada K, Kokudo N, Suzuki H, Kawamura YI.
    • Organizer
      American Association for Cancer Research Annual Meeting(米国癌学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08273
  • [Presentation] Loss of glutathione S-transferase omega 2 (GSTO2) predicts poor disease-free survival of lung adenocarcinoma2022

    • Author(s)
      住谷 隆輔、波多野 裕斗、山田 和彦、國土 典宏、河村 由紀.
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-22K08273
  • [Presentation] DNA hypermethylation and silencing of glutathione S-transferase omega 2 (GSTO2) in non-small cell lung cancer.2021

    • Author(s)
      Sumiya R, Hagiwara T, Nagasaka S, Kawamura YI.
    • Organizer
      The 25th Congress of the Asian Pacific Society of Respirology (APSR)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08457
  • [Presentation] Glutathione S-Transferase omega 2 (GSTO2) regulates cell growth and mitochondrial oxidative phosphorylation in lung squamous cell carcinoma.2021

    • Author(s)
      住谷隆輔、寺山仁祥、山田和彦、國土典宏、河村 由紀
    • Organizer
      第80回 日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-19K08457
  • [Presentation] 食道扁平上皮癌における新規癌抑制遺伝子GSTO2は細胞内代謝を制御することで増殖を制御する2020

    • Author(s)
      寺山 仁祥、山田 和彦、國土 典宏、河村 由紀.
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-19K08457
  • [Presentation] Glutathione S-transferase omega 2 (GSTO2) is a novel tumor suppressor gene of human lung squamous cell carcinoma2020

    • Author(s)
      Sumiya R, Terayama M, Hagiwara T, Sekihara K, Nagasaka S, Yamada K, Kokudo N, Kawamura YI.
    • Organizer
      American Association for Cancer Research (米国癌学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08457
  • [Presentation] Glutathione S-transferase omega 2 (GSTO2) suppresses cell growth and membrane localization of E-cadherin via p38MAPK signaling pathway in human esophageal squamous cells2020

    • Author(s)
      Terayama M, Yamada K, Hagiwara T, Dohi T, Kokudo N, Kawamura YI.
    • Organizer
      Digestive Disease Week Annual Meeting (米国消化器病週間学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08457
  • [Presentation] The characterization of the function of glutathione S-transferase omega 2 (GSTO2) indicated the presence of putative quiescent stem cells in human esophagus2019

    • Author(s)
      Terayama M, Yamada K, Hagiwara T, Inazuka F, Dohi T, Kokudo N, Kawamura YI.
    • Organizer
      Digestive Disease Week Annual Meeting (米国消化器病週間学会)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08457
  • [Presentation] E-cadherin expression correlates with progression of esophageal squamous cell carcinoma2019

    • Author(s)
      Koda H, Yamada K, Terayama M, Sumiya R, Nohara K, Enomoto N, Kataoka A, Mita H, Takemura N, Kiyomatsu T, Kokudo N, Kawamura YI.
    • Organizer
      The Annual Meeting of the European Society for Diseases of the Esophagus (欧州食道会議)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08457
  • [Presentation] 食道扁平上皮癌における新規癌抑制遺伝子GSTO2はE-カドヘリンの発現を抑制する2019

    • Author(s)
      寺山 仁祥、山田 和彦、國土 典宏、河村 由紀.
    • Organizer
      日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-19K08457
  • [Presentation] Glutathione S-transferase omega 2 (GSTO2) is a novel tumor suppressor gene in human esophageal squamous cell carcinoma.2018

    • Author(s)
      Terayama M, Yamada K, Inazuka F, Hagiwara T, Dohi T, Kokudo N, Kawamura YI.
    • Organizer
      Digestive Disease Week Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] Impact of dietary fat on cancer-predisposing luminal environment.2018

    • Author(s)
      Kawamura YI
    • Organizer
      The 37th Sapporo International Cancer Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] DNAメチル化亢進により食道扁平上皮癌特異的に発現低下を認めるGSTO2~組織型特異性の検討~.2018

    • Author(s)
      寺山 仁祥、山田 和彦、野原 京子、相馬 大介、安田 秀光、橋本 政典、矢野 秀朗、萩原 輝記、土肥 多恵子、河村 由紀
    • Organizer
      第73回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] Cystatin A (CSTA) expression relates to clinico-pathological stages in esophageal squamous cell carcinoma.2017

    • Author(s)
      Terayama M, Yamada K, Soma D, Kokudo N, Kawamura YI.
    • Organizer
      The 15th World Congress of the OESO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] DNA hypermethylation of PITX1 correlated with poor prognosis of esophageal squamous cell carcinoma.2017

    • Author(s)
      Yamada K, Otsubo T, Hagiwara T, Oshima K, Iida K, Nishikata K, Toyoda T, Igari T, Nohara K, Soma D, Kataoka A, Yamashita S, Hattori M, Dohi T, Kawamura YI.
    • Organizer
      The 28th Annual Meeting of the European Society for Diseases of the Esophagus (ESDE)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] Expression of the desmosome-related periplakin is associated with advanced stage of esophageal squamous cell carcinoma.2017

    • Author(s)
      Yamada K, Kawamura YI, Hagiwara T, Inazuka F, Sezaki T, Dohi T, Nohara K, Soma D, Yamashita S, Edamoto Y, Yano H, Hashimoto M, Kokudo N.
    • Organizer
      The 15th World Congress of the OESO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] 肥満と胃粘膜における壁細胞変化についての検討.2017

    • Author(s)
      山田和彦、河村由紀、横溝悠里子、中野(田村)美和、野原京子、相馬大介、山下智、横井千寿、猪狩亨、土肥多恵子.
    • Organizer
      第72回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] Expression of the desmosome-related periplakin is associated with advanced stage of esophageal squamous cell carcinoma.2017

    • Author(s)
      Yamada K, Kawamura YI, Hagiwara T, Inazuka F, Sezaki T, Dohi T, Nohara K, Soma D, Yamashita S, Edamoto Y, Yano H, Hashimoto M, Kokudo N.
    • Organizer
      The 15th World Congress of the OESO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] 食道扁平上皮癌におけるメチル化分析から得られたKallikrein-related peptidase 13 (KLK13) の発現と臨床病理学的検討2017

    • Author(s)
      山田和彦、河村由紀、萩原輝記、大坪武史、中野(田村)美和、土肥多惠子、野原京子、相馬大介、山下智、枝元良広、矢野秀朗、橋本政典.
    • Organizer
      第25回日本消化器関連学会週間(JDDW2017)
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] DNA hypermethylation of PITX1 correlated with poor prognosis of esophageal squamous cell carcinoma.2017

    • Author(s)
      Yamada K, Otsubo T, Hagiwara T, Oshima K, Iida K, Nishikata K, Toyoda T, Igari T, Nohara K, Soma D, Kataoka A, Yamashita S, Hattori M, Dohi T, Kawamura YI.
    • Organizer
      The 28th Annual Meeting of the European Society for Diseases of the Esophagus (ESDE)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] デスモゾーム関連分子であるperiplakinの発現は予後不良因子になる DNAメチル化と免疫染色での検討.2016

    • Author(s)
      山田 和彦, 河村 由紀, 萩原 輝記, 土肥 多恵子, 猪狩 亨, 山田 純, 野原 京子, 山下 智, 橋本 政典, 矢野 秀朗
    • Organizer
      日本消化器外科学会総会
    • Place of Presentation
      徳島
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] Expression of the desmosome-related molecule periplakin in esophageal squamous cell carcinoma2016

    • Author(s)
      Yamada K and Kawamura YI.
    • Organizer
      国際食道学会
    • Place of Presentation
      シンガポール
    • Year and Date
      2016-09-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] Integrative analysis of methylome and transcriptome detected loss of Rh type C-glycoprotein in esophageal squamous cell carcinoma.2016

    • Author(s)
      Shiba D, Yamada K, Nohara K, yamada J, Yamashita S, Yokoi C, Igari T, Hagiwara T, Dohi T, Kawamura Y.
    • Organizer
      国際食道学会
    • Place of Presentation
      シンガポール
    • Year and Date
      2016-09-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] デスモゾーム関連分子であるperiplakinの発現は予後不良因子になる.-DNAメチル化と免疫染色での検討-2016

    • Author(s)
      山田 和彦、河村 由紀、萩原 輝記、土肥 多恵子、山田 純、野原 京子、山下 智、橋本 政典、矢野 秀朗
    • Organizer
      日本消化器外科学会
    • Place of Presentation
      あわぎんホール、徳島
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] 高脂肪食が引き起こすマウス上部消化管病変2016

    • Author(s)
      平田 有基、瀬崎 拓人、樋口 和秀、河村 由紀、土肥 多惠子
    • Organizer
      日本消化器病学会大会
    • Place of Presentation
      神戸コンベンションセンター、神戸
    • Year and Date
      2016-11-03
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] 食道癌における網羅的メチル化解析より見出されたデスモソーム関連分子periplakinと臨床病理学的検討2016

    • Author(s)
      山田 和彦、河村 由紀、山田 純、野原 京子、山下 智、萩原 輝記、大坪 武史、中野(田村) 美和、瀬崎 拓人、土肥 多恵子、枝元 良広、徳原 真、橋本 政典、矢野 秀朗
    • Organizer
      日本外科学会定期学術集会
    • Place of Presentation
      大阪国際会議場、大阪
    • Year and Date
      2016-04-16
    • Data Source
      KAKENHI-PROJECT-16K09299
  • [Presentation] 食道癌における網羅的メチル化解析より見出されたデスモソーム関連分子periplakinと臨床病理学的検討.2016

    • Author(s)
      山田 和彦, 河村 由紀, 山田 純, 野原 京子, 山下 智, 萩原 輝記, 大坪 武史, 中野 美和[田村], 瀬崎 拓人, 土肥 多恵子, 枝元 良広, 徳原 真, 橋本 政典, 矢野 秀朗.
    • Organizer
      日本外科学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2016-04-14
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] 食道胃接合部癌におけるメチル化分析から得られたデスモソーム関連分子periplakinの意義2016

    • Author(s)
      山田 和彦、河村 由紀、萩原 輝記、平田 有基、土肥 多恵子、山田 純、野原 京子、山下 智、横井 千寿、小島 康志、橋本 政典
    • Organizer
      日本胃癌学会総会
    • Place of Presentation
      別府国際コンベンションセンター、大分
    • Year and Date
      2016-03-17
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] PRS27 is downregulated in esophageal squamous cell carcinoma in association with aberrant DNA hypermethylation.2016

    • Author(s)
      Sugimoto T, Hagiwara T, Yamada K, Oyama C, Tamura-Nakano M, Nohara K, Soma D, Yamashita S, Shiba D, Igari T, Yokoi C, Dohi T, Kawamura Y.
    • Organizer
      ヨーロッパ食道学会
    • Place of Presentation
      ミュンヘン
    • Year and Date
      2016-12-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] Integrative analysis of DNA methylome and transcriptome detected loss of a desmosome protein in esophageal squamous cell carcinoma2015

    • Author(s)
      Yuki I. Kawamura, Takeshi Otsubo, Teruki Hagiwara, Miwa Tamura-Nakano, Takuhito Sezaki, Oki Miyake, Toru Igari, Kazuhiko Yamada, Taeko Dohi
    • Organizer
      Digestive Disease Week Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2015-05-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] 消化器疾患で見られる糖鎖異常とエピジェネティックな遺伝子サイレンシング2015

    • Author(s)
      河村由紀
    • Organizer
      日本糖質学会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-31
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460965
  • [Presentation] 潰瘍性大腸炎における粘膜固有層免疫細胞のエピゲノム異常2015

    • Author(s)
      河村由紀、大坪武史、大島健志朗、豊田哲郎、萩原輝記、河村裕、小西文雄、矢野秀朗、斉藤幸夫、服部正平、土肥多恵子
    • Organizer
      日本消化器免疫学会総会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-31
    • Data Source
      KAKENHI-PROJECT-25460965
  • [Presentation] 食道扁平上皮癌でのデスモソーム関連分子periplakinとDNAメチル化異常について2015

    • Author(s)
      山田 和彦、河村 由紀、萩原 輝記、大坪 武史、中野(田村) 美和、瀬崎 拓人、土肥 多恵子、枝元 良広、橋本 政典、矢野 秀朗
    • Organizer
      日本消化器外科学会総会
    • Place of Presentation
      アクトシティ浜松、静岡
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] 食道扁平上皮癌のメチロームおよびトランスクリプトーム統合解析により見出されたデスモソーム関連分子periplakinの発現低下2015

    • Author(s)
      河村 由紀、大坪 武史、山田 和彦、猪狩 亨、土肥 多惠子
    • Organizer
      日本癌学会総会
    • Place of Presentation
      名古屋国際会議場、名古屋
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] Sialic-acid-binding Ig-like lectines, potential peripheral markers for mucosal damage of inflammatory bowel disease.2015

    • Author(s)
      Kawamura YI, Maeyashiki C, Hagiwara T, Otsubo T, Akiyama J, Dohi T.
    • Organizer
      United European Gastroenterology Week Annual Meeting
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-25460965
  • [Presentation] 食道癌のメチロームおよびトランスクリプトーム統合解析により見出されたホメオボックス遺伝子の発現低下2015

    • Author(s)
      河村 由紀、大坪 武史、山田 和彦、萩原 輝記、大島 健志朗、飯田 慶、西方 公郎、豊田 哲郎、猪狩 亨、山田 純、野原 京子、服部 正平、土肥 多惠子
    • Organizer
      日本生化学会大会
    • Place of Presentation
      神戸国際展示場、兵庫
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PROJECT-15K10124
  • [Presentation] Cell type-specific, genome-wide epigenetic analysis for lamina propria cells isolated from the colon with ulcerative colitis2013

    • Author(s)
      Otsubo T, Kawamura YI, Dohi T
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2013-12-11
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] TWEAK/Fn14 pathway promotes chronic colitis and fibrosis mediated by IL-13-TSLP axis2013

    • Author(s)
      Dohi T, Kawamura YI, Kawashima R, Son A, Oshio T, Wu P, Burkly LC
    • Organizer
      Immunology 2013
    • Place of Presentation
      Honolulu
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] バレット食道および食道腺癌におけるDNAメチル化異常2013

    • Author(s)
      萩原 輝記、秋山 純一、三宅 大、大坪 武史、櫻井俊之、清水利夫、土肥多惠子、河村由紀
    • Organizer
      第86回日本生化学会大会
    • Year and Date
      2013-09-13
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] Involvement of L1 retrotransposition in murine experimental colitis-cancer model2013

    • Author(s)
      Otusbo T, Kawamura YI, Ishizaka Y, Dohi T
    • Organizer
      DDW2013
    • Place of Presentation
      Orlando
    • Year and Date
      2013-05-20
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] DNA hypermethylation of the Sd^a carbohydrate synthase gene as a possible biomarker for the prognosis of ulcerative colitis2012

    • Author(s)
      Sakurai T、Kawamura YI、Hagiwara T、Otsubo T、Hirano Maeyashiki C、Kojima Y、Gotoda T、Yano H、Saito Y、Kawamura YJ、Konishi F、Dohi T
    • Organizer
      米国消化器病週間
    • Place of Presentation
      サンディエゴ
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] Genome-wide epigenomic analysis of lamina propria mononuclear cells of inflammatory bowel disease2012

    • Author(s)
      TA、Toyoda T、Hagiwara T、Kawamura YJ、Konishi F、Yano H、Saito Y、Hattori M、Dohi T
    • Organizer
      米国消化器病週間
    • Place of Presentation
      サンディエゴ
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] Epigenomic analysis for small cell numbers of lamina propria T cells and macrophage/dendritic cell fraction in ulcerative colitis2012

    • Author(s)
      大坪武史、遠藤高帆、豊田哲郎、大島健志朗、萩原輝記、河村裕、小西文雄、矢野秀朗、斉藤幸夫、服部正平、稲垣匡子、河村由紀、土肥多惠子
    • Organizer
      日本生化学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] TWEAK/Fn14 pathway promotes chronic colitis with Th2-type cytokine responses2012

    • Author(s)
      Dohi T, Son A, Kawamura YI, Inagaki-Ohara K, Oshio T, Burkly LC
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸(Oral presentation)
    • Year and Date
      2012-12-05
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] Genome-wide epigenomic analysis of lamina propria mononuclear cells isolated from patients with inflammatory bowel disease2012

    • Author(s)
      Kawamura YI、Otsubo T、Oshima K、Endo TA、Toyoda T、Hagiwara T、Kawamura YJ、Konishi F、Yano H、Saito Y、Hattori M、Dohi T
    • Organizer
      日米消化器病学会議
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] TWEAK/Fn14 pathway mediates IL-13 induced intestinal epithelial cell death2012

    • Author(s)
      Kawashima R, Kawamura YI, Oshio T, Hagiwara T, Okada T, Inagaki–Ohara K, Wu P, Szak S, Kawamura YJ, Konishi F, Miyake O, Yano H, Ichikawa T, Saito Y, Burkly LC And Dohi T
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2012-12-05
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] IL-13 induces TWEAK-dependent activation of TNF- and intestinal epithelial cell damage –a pathway associated with ulcerative colitis2012

    • Author(s)
      T Dohi, R Kawashima, YI Kawamura, T Oshio, M Yamazaki, T Hagiwara, T Okada, P Wu, S Szak, YJ Kawamura, F Konishi, O Miyake, H Yano, Y Saito, L. C. Burkly
    • Organizer
      Digestive Disease Week, 2012
    • Place of Presentation
      San Diego, U. S. A(Abstract in; Gastroenterology, Volume 142, Issue 5, Supplement 1, May 2012, PagesS-346-S-347)
    • Year and Date
      2012-05-19
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] IL-13による消化管粘膜傷害におけるTWEAK/Fn14経路の関連性2012

    • Author(s)
      川島 麗、土肥多惠子、河村由紀、川上文貴、市川尊文
    • Organizer
      第40回日本潰瘍学会
    • Place of Presentation
      東京
    • Year and Date
      2012-07-14
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] Interleukin-13 links to TWEAK/Fn14 pathway in intestinal epithelial cell injury2011

    • Author(s)
      Kawashima R, Kawamura YI, Oshio T, Son A, Yamazaki M, Hagiwara T, Okada T, Wu P, Szak S, Kawamura YJ, Konishi F, Miyake O, Yano H, Saito Y, Burkly LC, Dohi T
    • Organizer
      TNF 2011
    • Place of Presentation
      Awajishima, Hyogo
    • Year and Date
      2011-05-16
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] I.L-6, a Potent Inducer of DNA Hypermethylation and Malignant-Type Glycosylation in Ulcerative Colitis2011

    • Author(s)
      河村由紀
    • Organizer
      米国消化器病週間学会
    • Place of Presentation
      ニューオリンズ(米国)
    • Year and Date
      2011-05-03
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] Interleukin-13 links to TWEAK/Fn14 pathway in intestinal epithelial cell injury2011

    • Author(s)
      R Kawashima, YI Kawamura1, T Oshio, A Son, M Yamazaki, T Hagiwara, T Okada, P Wu, S Szak, YJ Kawamura, F Konishi, O Miyake, H Yano, Y Saito, LC Burkly, T Dohi.
    • Organizer
      TNF 2011
    • Place of Presentation
      Hyogo, Japan
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] IL-6, a potential inducer of DNA hypermethylation and malignant-type glycosylation in ulcerative colitis2011

    • Author(s)
      Kawamura YI、Toyota M、Hagiwara T、Suzuki H、Yamazaki M、Okada T、Kawamura YJ、Konishi F、Yano H、Saito Y、Dohi T
    • Organizer
      米国消化器病週間
    • Place of Presentation
      シカゴ
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] 消化管で見られる癌性糖鎖不全とエピゲノム異常.ワークショップ2癌のepigeneticsとmicroRNA2011

    • Author(s)
      河村由紀
    • Organizer
      日本病態治療研究会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-06-17
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] Establishment of a long term culture of self-replicating colon epithelial cells derived from a mouse model of inflammation-related tumor2011

    • Author(s)
      amazaki M、Kawamura YI、Okada T、Dohi T
    • Organizer
      米国消化器病週間
    • Place of Presentation
      シカゴ
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] 消化管でみられる癌性糖鎖不全とエピゲノム異常 ワークショップ2 癌のepigeneticsとmicroRNA2011

    • Author(s)
      河村由紀、豊田実、橋本真一、萩原輝記、山崎元美、河村裕、小西文雄、斉藤幸夫、服部正平、土肥多惠子
    • Organizer
      日本病態治療研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] IL-6 induces expression of DNA methyltransferases, gene silencing, and malignant-type glycosylation in ulcerative colitis and colitic cancer.2010

    • Author(s)
      河村由紀
    • Organizer
      米国消化器病週間学会
    • Place of Presentation
      ニューオリンズ(米国)
    • Year and Date
      2010-05-03
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] パレット食道癌における粘液形質異常2010

    • Author(s)
      河村由紀
    • Organizer
      第52回日本消化器病学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] IL-6 induces expression of DNA methyltransferases, gene silencing, and malignant-type glycosylation in ulcerative colitis and colitic cancer2010

    • Author(s)
      Kawamura YI、Toyota M、Kawashima R、Okada T、Hagiwara T、Kawamura YJ、Konishi F、Matsumoto T、Dohi T
    • Organizer
      米国消化器病週間
    • Place of Presentation
      ニューオリンズ
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] IL-6誘導性DNA高メチル化がもたらす潰瘍性大腸炎およびcolitic cancerの糖鎖異常2010

    • Author(s)
      河村由紀、豊田実、川島麗、萩原輝記、河村裕、小西文雄、斉藤幸夫、松本誉之、神奈木玲児、今井浩三、土肥多惠子
    • Organizer
      日本生化学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] IL-6はDNAメチル基転移酵素の異所性発現を介して潰瘍性大腸炎における糖鎖異常を誘導する2010

    • Author(s)
      河村由紀、豊田実、Vongsavanh Phongsisay、岡田俊彦、山崎元美、河村裕、小西文雄、斉藤幸夫、鈴木拓、神奈木玲児、松本誉之、今井浩三、土肥多惠子
    • Organizer
      日本癌学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] IL-6はDNAメチル基転移酵素の異所性発現を介して潰瘍性大腸炎における糖鎖発現異常を誘導する2010

    • Author(s)
      河村由紀
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] バレット食道癌における粘液形質異常 ワークショップ22 Barrett食道のサーベイランス・治療を巡って2010

    • Author(s)
      河村由紀、秋山純一、土肥多惠子
    • Organizer
      日本消化器病学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] Interleukin-13 Induces Tissue Damage with Relocation ofβ-Catenin and Modification of Cell-Cell Adhesion in the Epithelial Cells.2008

    • Author(s)
      Kawashima R, Kawamura YI, Mizutani N, Toyama-Sorimachi N, Dohi T
    • Organizer
      Digestive Disease Week 2008, Selected as Poster of distinction
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2008-05-20
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] DNA hypermethylation causes cancer-associated changes of carbohydrate determinants by silencing‘glyco-genes' in gastrointestinal cancer2008

    • Author(s)
      Kawamura YI、Toyota M、Kawashima R、Hagiwara T、Kawamura YJ、Dohi T
    • Organizer
      米国消化器病週間
    • Place of Presentation
      サンディエゴ
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] Tweak/Fn14 Pathway: Role in the Intestinal Inflammation and Tissue Repair.2008

    • Author(s)
      Dohi T, Borodovsky A, Kawashima R, Wu P, Kawamura YI, Burkly LC
    • Organizer
      Digestive Disease Week 2008, Selected as Poster of distinction
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2008-05-18
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] Inflammation-associated transcriptional silencing of Sda carbohydrate-synthase gene by DNA hypermethylation in ulcerative colitis.2008

    • Author(s)
      Kawamura YI, Toyota M, Kawashima R, Hagiwara T, Kawamura YJ, Konishi F, Saito Y, Kannagi R, Imai K, Dohi T.
    • Organizer
      Biochemistry and Molecular Biology (BMB) 2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] Comprehensive analysis of lectin-binding in the colitis and colitis-associated tumors in mice.2008

    • Author(s)
      V Phongsisay, Y I. Kawamura, R Kawashiama, T Dohi
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] Inflammation-associated transcriptional silencing of Sda carbohydrate-synthase gene by DNA hypermethylation in ulcerative colitis.2008

    • Author(s)
      河村 由紀
    • Organizer
      第81回 日本生化学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] IL-13 disrupts tight junction in the intestinal epithelial cells by modulating expression of ZO-1, ocdudin and claudin-2.2008

    • Author(s)
      Kawashima R, Kawamura YI. Toayama-Sorimachi N, Dohi T
    • Organizer
      第38回日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-02
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] 消化器癌における糖鎖関連遺伝子のDNAメチル化によるサイレンシング2008

    • Author(s)
      河村由紀、豊田実、土肥多恵子
    • Organizer
      日本消化器病学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] Inflammation-associated transcriptional silencing of Sda carbohydrate-synthase gene by DNA hypermethylation in ulcerative colitis2008

    • Author(s)
      Y I. Kawamura
    • Organizer
      Biochemistry and Molecular Biology (BMB) 2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] DNA異常メチル化により引き起こされる消化管の癌性糖鎖不全現象2008

    • Author(s)
      河村由紀、豊田実、川島麗、萩原輝記、鈴木拓、篠村恭久、時野隆至、今井浩三、土肥多恵子
    • Organizer
      臨床分子医学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] 潰瘍性大腸炎および大腸癌におけるSda糖鎖合成酵素遺伝子のDNA異常メチル化による転写抑制2008

    • Author(s)
      河村由紀、豊田実、川島麗、河村裕、小西文雄、斉藤幸夫、矢島知治、日比紀文、松本誉之、神奈木玲児、今井浩三、土肥多恵子
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] Inflammation-associated transcriptional silencing of Sda carbohydrate-synthase gene by DNA hypermethylation in ulcerative colitis2008

    • Author(s)
      河村由紀、豊田実、川島麗、萩原輝記、河村裕、小西文雄、斉藤幸夫、神奈木玲児、今井浩三、土肥多恵子
    • Organizer
      日本生化学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] Silencing of Sd^a carbohydrate-synthase gene by aberrant methylation in gastrointestinal cancer and ulcerative colitis2007

    • Author(s)
      Kawamura YI.
    • Organizer
      13th International Congress of Mucosal Immunology
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-07-10
    • Data Source
      KAKENHI-PROJECT-18012053
  • [Presentation] Transcriptional silencing of glycosylation-related genes by DNA hypermethylation in gastrointestinal cancer2007

    • Author(s)
      Kawamura YI
    • Organizer
      日本生化学会
    • Place of Presentation
      日本生化学会
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-18012053
  • [Presentation] Siglecs, ligands for carbohydrate determinants on nonmalignant colonic epithelial cells, are expressed in the colonic lamina propria cells2007

    • Author(s)
      河村由紀、川島麗、水谷紀子、反町典子、神奈木玲児、土肥多恵子
    • Organizer
      日本免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] Interleukin-13 disrupts the cell-cell adhesion of intestinal epithelial cells2007

    • Author(s)
      Kawashima R, Kawamura YI, Mizutani N, Toyama-Sorimachi N Dohi T
    • Organizer
      第37回日本免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] Glyco XIX2007

    • Author(s)
      Kawamura YI、Toyota M、Kawashima R、S aito Y、Miyake O、Takeshita E、Kawamura YJ、Konishi F、Kannagi R、Dohi T
    • Organizer
      Glyco XIX、ケアンズ
    • Place of Presentation
      ケアンズ
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] Cancer-associated transcriptional silencing of glycosyltransferase by DNA hypermethylation2007

    • Author(s)
      河村由紀、豊田実、川島麗、斉藤幸夫、神奈木玲児、土肥多恵子
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] Silencing of Sd^a carbohydrate-synthase gene by aberrant methylation in gastrointestinal cancer and ulcerative colitis2007

    • Author(s)
      Kawamura YI
    • Organizer
      13th International Congress of Mucosal Immunology
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-07-10
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] Siglecs,ligands for carbohydrate determinants on nonmalignant colonicepithelial cells,are expressed in the colonic lamina propria cells2007

    • Author(s)
      Kawamura YI
    • Organizer
      第37回日本免疫学会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-18012053
  • [Presentation] Siglecs,ligands for carbohydrate determinants on nonmalignant colonicepithelial cells,are expressed in the colonic lamina propria cells2007

    • Author(s)
      河村 由紀
    • Organizer
      第37回 日本免疫学会総会
    • Place of Presentation
      品川
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] Fractalkine Regulates TNF-alfa secretion by macrophages with induction of peroxisome proliferator-activated receptor-gamma and its ligand2007

    • Author(s)
      Mizutani N, Sakurai T, Shibata T, Uchida K, Fujita J, Kawashima R, Kawamura YI, Toyama-Sorimachi N, Imai T, Dohi T
    • Organizer
      Digestive Disease Week 2007
    • Place of Presentation
      Washington D.C.
    • Year and Date
      2007-05-23
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] Aberrant responses of human colonic macrophage-type cells to lipopolysaccharide in ulcerative colitis: upregulated expression of MD-2 and production of Inflammatory cytokines2007

    • Author(s)
      Kawashima R, Kawamura YI, Mizutani N, Toyama-Sorimachi N, Saito Y, Kawamura YJ, Fumio, Konishi, Dohi T
    • Organizer
      Digestive Disease Week 2007
    • Place of Presentation
      Washington D.C.
    • Year and Date
      2007-05-22
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] Epigenetic mechanism for cancer-associated silencing of a gene encoding abetal,4N-acetylgalactosaminyltransferase,which is exclusively expressed in normal gastrointestinal mucosa2007

    • Author(s)
      Kawamura YI.
    • Organizer
      Glyco XIX(XIX International Symposium on Glycoconjugates)
    • Place of Presentation
      Cairns,Australia
    • Year and Date
      2007-07-17
    • Data Source
      KAKENHI-PROJECT-18012053
  • [Presentation] Transcriptional silencing of glycosylation-related genes by DNA hypermethylation in gastrointestinalcancer2007

    • Author(s)
      河村由紀、豊田実、川島麗、萩原輝記、斉藤幸夫、神奈木玲児、土肥多恵子
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] Silencing of Sda carbohydrate-synthase gene by aberrant methylation in gastrointestinal cancer and ulcerative colitis2007

    • Author(s)
      Kawamura YI, Toyota M, Kawashima R, Hagiwara T, Kawamura YJ, Konishi F, Takeshita E, Miyake O, Saito Y, Kannagi R, T Dohi
    • Organizer
      13th International Congress of Mucosal Immunology
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-07-10
    • Data Source
      KAKENHI-PROJECT-19390204
  • [Presentation] Silencing of Sda carbohydrate-synthase gene by aberrant methylation in gastrointestinal cancer and ulcerative colitis2007

    • Author(s)
      Kawamura YI、Toyota M、Kawashima R、Saito Y、Kawamura YJ、Konishi F、Kannagi R、Dohi T
    • Organizer
      国際粘膜免疫学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19790504
  • [Presentation] DNA hypermethylation of the Sda carbohydrate synthase gene as a possible biomarker for the prognosis of ulcerative colitis

    • Author(s)
      Sakurai T, Kawamura YI, Hagiwara T, Otsubo T, Hirano Maeyasiki C, Kojima Y, Gotoda T, Yano H, Saito Y, Kawamura YJ, Konishi F, Dohi T
    • Organizer
      Digestive Disease Week Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] Involvement of L1 retrotransposition in murine experimental colitis-cancer model.

    • Author(s)
      Otusbo T, Kawamura YI, Ishizaka Y, Dohi T
    • Organizer
      DDW2013
    • Place of Presentation
      Orlando
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] バレット食道および食道腺癌におけるDNAメチル化異常

    • Author(s)
      萩原 輝記、秋山 純一、三宅 大、大坪 武史、櫻井 俊之、清水 利夫、土肥 多惠子、河村 由紀
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] IL-13 induces TWEAK-dependent activation of TNF-α and intestinal epithelial cell damage –a pathway associated with ulcerative colitis.

    • Author(s)
      T Dohi, R Kawashima, YI Kawamura, T Oshio, M Yamazaki, T Hagiwara, T Okada, P Wu, S Szak, YJ Kawamura, F Konishi, O Miyake, H Yano, Y Saito, L. C. Burkly
    • Organizer
      Digestive Disease Week, 2012
    • Place of Presentation
      San Diego, U. S. A
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] TWEAK/Fn14 pathway promotes chronic colitis and fibrosis mediated by IL-13-TSLP axis.

    • Author(s)
      Dohi T, Kawamura YI, Kawashima R, Son A, Oshio T, Wu P, Burkly LC.
    • Organizer
      Immunology 2013
    • Place of Presentation
      Honolulu
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] TWEAK/Fn14 pathway promotes chronic colitis with Th2-type cytokine responses.

    • Author(s)
      Dohi T, Son A, Kawamura YI, Inagaki-Ohara K, Oshio T, Burkly LC
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] IL-13 induces TWEAK-dependent activation of TNF-α and intestinal epithelial cell damage –a pathway associated with ulcerative colitis

    • Author(s)
      Dohi T, Kawashima R, Kawamura YI, Oshio T, Yamazaki M, Hagiwara T, Okada T, Wu P, Szak A, Kawamura YJ, Konishi F, Miyake O, Yano H, Saito Y, Burkly LC
    • Organizer
      Digestive Disease Week Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] Genome-wide epigenomic analysis of lamina propria mononuclear cells isolated from patients with inflammatory bowel disease

    • Author(s)
      Kawamura YI, Otsubo T, Oshima K, Endo TA, Toyoda T, Hagiwara T, Kawamura YJ, Konishi F, Yano H, Saito Y, Hattori M, Dohi T
    • Organizer
      The 6th Japan & US Collaboration Conference in Gastroenterology
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] IL-13による消化管粘膜傷害におけるTWEAK / Fn14経路の関連性

    • Author(s)
      川島麗、土肥多惠子、河村由紀、川上文貴、市川尊文
    • Organizer
      第40回日本潰瘍学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] Genome-wide epigenomic analysis of lamina propria mononuclear cells of inflammatory bowel disease

    • Author(s)
      Otsubo T, Kawamura YI, Oshima K, Endo TA, Toyoda T, Hagiwara T, Kawamura YJ, Konishi F, Yano H, Saito Y, Hattori M, Dohi T
    • Organizer
      Digestive Disease Week Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] 末梢血白血球レクチン発現は炎症性腸疾患の病勢を反映するマーカーである

    • Author(s)
      前屋舗 千明、河村 由紀、萩原 輝記、大坪 武史、櫻井 俊之、永田 尚義、小島 康志、秋山 純一、神奈木 玲児、土肥 多恵子
    • Organizer
      第99回 日本消化器病学会総会
    • Place of Presentation
      城山観光ホテル・かごしま県民交流センター(鹿児島県)
    • Data Source
      KAKENHI-PROJECT-22590712
  • [Presentation] TWEAK/Fn14 pathway mediates IL-13 induced intestinal epithelial cell death.

    • Author(s)
      Kawashima R, Kawamura YI, Oshio T, Hagiwara T, Okada T, Inagaki–Ohara K, Wu P, Szak S, Kawamura YJ, Konishi F, Miyake O, Yano H, Ichikawa T, Saito Y, Burkly LC And Dohi T
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23590955
  • [Presentation] Cell type-specific, genome-wide epigenetic analysis for lamina propria cells isolated from the colon with ulcerative colitis.

    • Author(s)
      Otsubo T, Kawamura YI, Dohi T.
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23590955
  • 1.  DOHI Taeko (60250221)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 35 results
  • 2.  KAWASHIMA Rei (70392389)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 3.  IZUHARA Kenji (00270463)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  ATSUSHI Nishikawa (30218127)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TOYOTA Minoru (70270676)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 6.  ISHIZAKA Yukihito (30281687)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  OTSUBO Takeshi (00623034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  Yamada Kazuhiko (70401081)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 9.  Ichikawa Takafumi (30245378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  Hase Koji (20359714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  相馬 大介 (80636613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  田久保 圭誉 (50502788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  松田 幹 (20144131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  久保 誠 (40464804)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  伊藤 尚志 (90383629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  BURKLY Linda C.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 17.  SAKUMA Keiichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  神奈木 玲児
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  小薗 拓馬
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  箕越 靖彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  住谷 隆輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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