Kubota Kosei 久保田耕世

… Alternative Names

KUBOTA Kousei 久保田耕世

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Researcher Number	10529689
Other IDs
Affiliation (Current)	2025: 弘前大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2025: 弘前大学, 医学部附属病院, 講師 2017 – 2022: 弘前大学, 医学部附属病院, 講師 2011 – 2014: 弘前大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related Except Principal Investigator Basic Section 57080:Social dentistry-related / Surgical dentistry
Keywords	Principal Investigator 口腔粘膜炎 / 遺伝子 / 歯学 / がん関連線維芽細胞 / 骨芽細胞 / 遺伝子発現 / 癌微小環境 / 口腔癌 / 免疫学 Except Principal Investigator 予防医療 … More / 大規模縦断研究 / 予兆発見 / 加齢関連疾患 / 口腔内細菌 / 骨増生法 / 臨床 / 細胞・組織 / 移植・再生医療 / 歯学 / 骨リモデリング / BMP signaling / Wnt signaling / メカニカルストレス / BMP pathway / Wnt pathway / 骨代謝 / メカノセンサー / 骨膜 Less

口腔内細菌を活用した加齢関連疾患の発症予兆検知を目指す大規模長期縦断研究
- Principal Investigator
  
  松宮朋穂
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Hirosaki University
Mechanisms of bone exposure of jaw associated with chemotherapy-induced oral mucositis in oral cancerPrincipal Investigator
- Principal Investigator
  
  Kubota Kosei
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hirosaki University
Development of novel treatment for oral mucositis focused on specific immune system in cancer stromaPrincipal Investigator
- Principal Investigator
  
  Kubota Kosei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hirosaki University
The study on RIG-I and cancer associated fibroblast function for the regulation of mucositis induced by chemotherapyPrincipal Investigator
- Principal Investigator
  
  KUBOTA Kosei
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hirosaki University
Development of the new bone regeneration method by transplanting jawbone periosteum sheets as a mechanosensor.
- Principal Investigator
  
  KIMURA Hiroto
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hirosaki University
The study on RIG-I function analysis for establishment of innovativetherapy for mucositis induced by chemotherapyPrincipal Investigator
- Principal Investigator
  
  KUBOTA Kosei
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hirosaki University

All 2022 2021 2020 2019 2018 2014 2012 2011 Other

All Journal Article Presentation

[Journal Article] Utility of prognostic nutritional index and systemic immune-inflammation index in oral cancer treatment2022
- Author(s)
  Kosei Kubota, Ryohei ito, Norihiko Narita, Yusuke Tanaka, Ken Furudate, Natsumi Akiyama, Chuang Hao Chih, Shotaro Komatsu and Wataru Kobayashi
- Journal Title
  
  BMC Cancer
  
  Volume: 22(1) Issue: 1 Pages: 368-368
- DOI
  10.1186/s12885-022-09439-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10088, KAKENHI-PROJECT-20K18716
[Journal Article] Inflammation based prognostic scoreを用いた口腔癌の予後因子の検討2020
- Author(s)
  久保田耕世,伊藤良平,成田紀彦,中川祥,田中祐介,福田はるか,小林恒
- Journal Title
  
  口腔腫瘍学会誌
  
  Volume: 32 Pages: 9-14
- NAID
  130007814254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11824
[Journal Article] Periosteum-derived cells respond to mechanical stretch and activate Wnt andBMP signaling pathways2014
- Author(s)
  Ito R, Matsumiya T, Kon T, Narita N, Kubota K, Sakaki H, Ozaki T, Imaizumi T, Kobayashi W, Kimura H
- Journal Title
  
  Biomed. Res.
  
  Volume: 35 Issue: 1 Pages: 69-79
- DOI
  10.2220/biomedres.35.69
- NAID
  130004903861
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592979
[Journal Article] Periosteum-derived cells respond to mechanical stretch and activate Wnt and BMP signaling pathways2014
- Author(s)
  Ryohei Ito, Tomoh Matsumiya, Takao Kon, Norihiko Narita, Kosei Kubota, Hirotaka Sakaki, Hidemi Yoshida, Tadaatsu Imaizumi, Wataru Kobayashi, Hiroto Kimura
- Journal Title
  
  Biomedical Reserch
  
  Volume: vol.35 Pages: 69-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592979
[Journal Article] 口腔癌頸部リンパ節転移に対するドセタキセルとネダプラチンによる超選択的動注を用いた化学放射線療法の有効性2012
- Author(s)
  小林恒・佐藤寿・榊宏剛・中川祥・久保田耕世・成田憲司・今敬生・成田紀彦・鄭明源・木村博人
- Journal Title
  
  日本口腔科学会雑誌
  
  Volume: 61巻1号 Pages: 8-15
- NAID
  10030795626
- Data Source
  KAKENHI-PROJECT-23792308
[Presentation] 口腔癌における予後推定栄養指数と全身性免疫炎症指数の有用性について2022
- Author(s)
  久保田　耕世、伊藤　良平、古舘　健、小林　恒
- Organizer
  第46回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-20K10088
[Presentation] 口腔癌動注化学放射線療法による好中球減少予防に対するペグフィルグラスチムの使用経験について2022
- Author(s)
  久保田　耕世　伊藤　良平　成田　紀彦　古舘　健　福田　はるか　小林　恒
- Organizer
  第40回口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20K10088
[Presentation] 口腔癌動注化学放射線療法による好中球減少予防に対するペグフィルグラスチムの使用経験について2022
- Author(s)
  久保田耕世、伊藤良平、成田紀彦、古舘健、福田はるか、秋山なつみ、小林恒
- Organizer
  第４０回日本口腔腫瘍学会総会・学術大会について
- Data Source
  KAKENHI-PROJECT-20K10088
[Presentation] 歯肉癌由来がん関連線維芽細胞の免疫学的応答能について2021
- Author(s)
  久保田　耕世、伊藤　良平、田中　祐介、福田はるか、中川　祥、小林　恒
- Organizer
  日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K10088
[Presentation] 口腔癌動注化学放射線科療法における予後推定栄養指数の有用性2020
- Author(s)
  久保田耕世,　伊藤良平,　田中祐介,　中川　祥,　福田はるか,　小林　恒
- Organizer
  第38回日本口腔腫瘍学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11824
[Presentation] Inflammation based prognostic scoreを用いた口腔癌の予後因子の検討2019
- Author(s)
  久保田　耕世、伊藤　良平、成田　紀彦、今　敬生、中川　祥、福田　はるか、小林　恒
- Organizer
  口腔腫瘍学会
- Data Source
  KAKENHI-PROJECT-17K11824
[Presentation] 口腔癌由来がん関連線維芽細胞の腫瘍免疫学的役割について2019
- Author(s)
  久保田耕世,　伊藤良平,　田中祐介,　福田はるか,　佐竹杏奈,　秋山なつみ,　中川　祥,　小林　恒
- Organizer
  第64回（公社）日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-17K11824
[Presentation] 口腔癌由来がん関連線維芽細胞の比較検討2018
- Author(s)
  久保田　耕世、伊藤　良平、成田　紀彦、福田　はるか、今　敬生、中川　祥、小林　恒
- Organizer
  口腔腫瘍学会
- Data Source
  KAKENHI-PROJECT-17K11824
[Presentation] Study on Cancer-associated fibroblasts derived from oral cancer2018
- Author(s)
  Kosei KUBOTA, Ken FURUDATE, Takao KON, Anna SATAKE, Haruka FUKUDA, Wataru KOBAYASHI
- Organizer
  Asian Congress on Oral and Maxillofacial Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11824
[Presentation] 骨膜由来細胞はメカニカルストレスに応答しWnt signaling pathwayと BMP signaling pathwayが活性化される2014
- Author(s)
  伊藤　良平、佐藤　寿、榊　宏剛、久保田　耕世、今　敬生、小林　恒、木村　博人
- Organizer
  日本口腔科学会
- Place of Presentation
  東京都新宿区
- Data Source
  KAKENHI-PROJECT-23592979
[Presentation] WeeklyDocetaxel静注併用放射線療法を施行した高齢者頭頚部癌5症例の検討2011
- Author(s)
  久保田耕世
- Organizer
  第56回日本口腔外科学会総会・学術大会
- Place of Presentation
  大阪
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23792308
[Presentation] RIG-Iは口腔癌由来細胞株において細胞周期の制御に関与する2011
- Author(s)
  榊宏剛・松宮朋穂・久保田耕世・中川祥・小林恒・木村博人
- Organizer
  第56回日本口腔外科学会総会・学術大会
- Place of Presentation
  大阪
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23792308
[Presentation] 行口腔癌に対する動注化学放射線療法後の放射線性顎骨壊死に関する臨床的検討
- Author(s)
  小林恒・佐藤寿・榊宏剛・久保田耕世・今敬生・中川祥・成田紀彦・木村博人・鄭明源
- Data Source
  KAKENHI-PROJECT-23792308
[Presentation] がん関連線維芽細胞と正常歯肉線維芽細胞の初期免疫応答能に関する比較検討
- Author(s)
  久保田　耕世、伊藤　良平、古舘　健、中川　祥、榊　宏剛、小林　恒、木村　博人
- Organizer
  日本口腔科学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-05-13 – 2015-05-15
- Data Source
  KAKENHI-PROJECT-25861907
[Presentation] 正常歯肉線維芽細胞とがん関連線維芽細胞の比較検討
- Author(s)
  久保田　耕世、中川　祥、今　敬生、小林　恒、木村　博人
- Organizer
  口腔腫瘍学会
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2015-01-29 – 2015-01-30
- Data Source
  KAKENHI-PROJECT-25861907

1. MATSUMIYA Tomoh (30344592)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. WATARU Kobayashi (50234860)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. KIMURA Hiroto (90142851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. NAKAGAWA Hiroshi (00529688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SAKAKI Hirotaka (90374850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. ITO Ryohei (20638902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 田村好拡 (30770789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山内可南子 (80740810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kubota Kosei 久保田 耕世

KUBOTA Kousei 久保田 耕世

Research Projects

Research Products

Co-Researchers

口腔内細菌を活用した加齢関連疾患の発症予兆検知を目指す大規模長期縦断研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of bone exposure of jaw associated with chemotherapy-induced oral mucositis in oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel treatment for oral mucositis focused on specific immune system in cancer stromaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study on RIG-I and cancer associated fibroblast function for the regulation of mucositis induced by chemotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the new bone regeneration method by transplanting jawbone periosteum sheets as a mechanosensor.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study on RIG-I function analysis for establishment of innovativetherapy for mucositis induced by chemotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Utility of prognostic nutritional index and systemic immune-inflammation index in oral cancer treatment2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inflammation based prognostic scoreを用いた口腔癌の予後因子の検討2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Periosteum-derived cells respond to mechanical stretch and activate Wnt andBMP signaling pathways2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Periosteum-derived cells respond to mechanical stretch and activate Wnt and BMP signaling pathways2014

Author(s)

Journal Title

Data Source

[Journal Article] 口腔癌頸部リンパ節転移に対するドセタキセルとネダプラチンによる超選択的動注を用いた化学放射線療法の有効性2012

Author(s)

Journal Title

NAID

Data Source

[Presentation] 口腔癌における予後推定栄養指数と全身性免疫炎症指数の有用性について2022

Author(s)

Organizer

Data Source

[Presentation] 口腔癌動注化学放射線療法による好中球減少予防に対するペグフィルグラスチムの使用経験について2022

Author(s)

Organizer

Data Source

[Presentation] 口腔癌動注化学放射線療法による好中球減少予防に対するペグフィルグラスチムの使用経験について2022

Author(s)

Organizer

Data Source

Kubota Kosei 久保田耕世

KUBOTA Kousei 久保田耕世