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Okudaira Noriyuki  奥平 准之

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… Alternative Names

奥平 准之  オクダイラ ノリユキ

OKUDAIRA Noriyuki  奥平 准之

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Researcher Number 10635585
Other IDs
Affiliation (Current) 2022: 帝京大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2020: 埼玉医科大学, 医学部, 実験助手
2020: 帝京大学, 医学部, 助教
2015 – 2018: 明海大学, 歯学部, 助教
2012 – 2015: 兵庫医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Legal medicine / Basic Section 38050:Food sciences-related
Except Principal Investigator
Legal medicine / Pathobiological dentistry/Dental radiology / Basic Section 57060:Surgical dentistry-related / Basic Section 57010:Oral biological science-related
Keywords
Principal Investigator
LINE-1 / ゲノム不安定性 / レトロエレメント / RyR2 / 突然死 / 胸腺 / 心電図 / 遺伝子組換えマウス / miRNA / 遺伝子改変マウス … More / 乱用薬物 / イミプラミン / NR2A / MAPK / レトロトランスポジション / モルヒネ / クエン酸フェンタニル / TLR4 / DSB / retrotransposition / resveratrol / Sirtuin6 / PPARα / 発がん物質 … More
Except Principal Investigator
クロモン誘導体 / 腫瘍選択性 / 選択毒性 / 胸腺 / 突然死 / 不整脈 / RyR2 / カルシウム動態 / 遺伝性不整脈原因遺伝子 / クロモン環 / 口腔扁平上皮癌細胞 / アポトーシス / 分子軌道解析 / 細胞周期 / カスパーゼ-3 / QSAR解析 / 3次元構造 / アポトーシス誘導能 / subG1 / スチリルクロモン / ピペリン酸エステル / オーロン / QSAR / 置換基 / 化学記述子 / 3-スチリルクロモン類 / ヒト口腔扁平上皮癌 / 有機合成 / 作用機序 / 副作用の緩和 / ハイパーサーミア / 低侵襲性治療 / 腫瘍選択性磁性体 / 口腔癌 / 併用療法 / 細胞透過性ペプチド / Geranylgeraniol / ヒト口腔扁平上皮がん細胞 / 細胞への取り込み / クロモン誘導体の標識 / 作用点 / 遺伝子発現 / 代謝物変化 / 細胞死 / 口腔扁平上皮癌 / シグナル伝達 Less
  • Research Projects

    (7 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (21 People)
  •  Development of minimally invasive therapy for oral cancer by hyperthermia with tumor-specific targeting magnetic nanoparticles

    • Principal Investigator
      藤内 祝
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Meikai University
  •  加熱食品由来発癌物質のゲノム不安定性作用に対するレスベラトロールの遺伝子制御機構Principal Investigator

    • Principal Investigator
      奥平 准之
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Teikyo University
  •  Elucidation of selective cytotoxicity against malignant cells by chromone derivatives

    • Principal Investigator
      坂上 宏
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Meikai University
  •  Basic study of the possibility of newly synthesized 3-styrylchromone derivatives as therapeutic drugs for oral cancer

    • Principal Investigator
      Sakagami Hiroshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Meikai University
  •  Long interspersed element-1 retrotransposition induced by abuse drugsPrincipal Investigator

    • Principal Investigator
      OKUDAIRA Noriyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Legal medicine
    • Research Institution
      Meikai University
  •  Pathophysiological study of the mice with thymicolymphaticus-like phenotypes

    • Principal Investigator
      Nishio Hajime
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      Hyogo College of Medicine
  •  Immunobiological analysis of cardiac muscle type ryanodine receptor genetic mutation micePrincipal Investigator

    • Principal Investigator
      OKUDAIRA Noriyuki
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Legal medicine
    • Research Institution
      Hyogo College of Medicine

All 2018 2017 2016 2015 2013 Other

All Journal Article Presentation

  • [Journal Article] Quantitative Structure-Cytotoxicity Relationship of 2-(N-cyclicamino)chromone Derivatives2018

    • Author(s)
      SHI HAIXIA、NAGAI JUNKO、SAKATSUME TSUKASA、BANDOW KENJIRO、OKUDAIRA NORIYUKI、SAKAGAMI HIROSHI、TOMOMURA MINEKO、TOMOMURA AKITO、UESAWA YOSHIHIRO、TAKAO KOICHI、SUGITA YOSHIAKI
    • Journal Title

      Anticancer Res

      Volume: 38 Pages: 3897-3906

    • DOI

      10.21873/anticanres.12674

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-16K11519
  • [Journal Article] Quantitative Structure-Cytotoxicity Relationship of Pyrano[4,3-b]chromones2018

    • Author(s)
      NAGAI JUNKO、SHI HAIXIA、KUBOTA YUKA、BANDOW KENJIRO、OKUDAIRA NORIYUKI、UESAWA YOSHIHIRO、SAKAGAMI HIROSHI、TOMOMURA MINEKO、TOMOMURA AKITO、TAKAO KOICHI、SUGITA YOSHIAKI
    • Journal Title

      Anticancer Res

      Volume: 38 Pages: 4449-4457

    • DOI

      10.21873/anticanres.12747

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-16K11519
  • [Journal Article] Quantitative Structure-Cytotoxicity Relationship of 3-(N-Cyclicamino)chromone Derivatives2018

    • Author(s)
      SHI HAIXIA、NAGAI JUNKO、SAKATSUME TSUKASA、BANDOW KENJIRO、OKUDAIRA NORIYUKI、UESAWA YOSHIHIRO、SAKAGAMI HIROSHI、TOMOMURA MINEKO、TOMOMURA AKITO、TAKAO KOICHI、SUGITA YOSHIAKI
    • Journal Title

      Anticancer Res

      Volume: 38 Pages: 4459-4467

    • DOI

      10.21873/anticanres.12748

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11487, KAKENHI-PROJECT-16K11519
  • [Journal Article] Quantitative Structure?Cytotoxicity Relationship of 2-Azolylchromones2018

    • Author(s)
      Sakagami H, Okudaira N, Uesawa Y, Takao K, Kagaya H, Sugita Y
    • Journal Title

      Anticancer Research

      Volume: 38 Pages: 763-770

    • DOI

      10.21873/anticanres.12282

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11519, KAKENHI-PROJECT-15K08111
  • [Journal Article] Quantitative Structure?Cytotoxicity Relationship of Cinnamic Acid Phenetyl Esters2018

    • Author(s)
      Uesawa Y, Sakagami H, Okudaira N, Toda K, Takao K, Kagaya H and Sugita Y
    • Journal Title

      Anticancer Research

      Volume: 38 Pages: 817-823

    • DOI

      10.21873/anticanres.12289

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11519, KAKENHI-PROJECT-15K08111
  • [Journal Article] Induction of Apoptosis in human oral keratinocyte by doxorubicin.2017

    • Author(s)
      Sakagami H, Okudaira N, Masuda Y, Amano O, Yokose S, Kanda Y, Suguro M, Natori T, Oizumi H and Oizumi T
    • Journal Title

      Anticancer Research

      Volume: 37 Pages: 1023-1029

    • DOI

      10.21873/anticanres.11412

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11519
  • [Journal Article] トランスポゾンの歴史と食品への利用2016

    • Author(s)
      奥平准之
    • Journal Title

      New Food Industry

      Volume: 58 Pages: 29-32

    • NAID

      40020832743

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Journal Article] Morphine and Fentanyl Citrate Induce Retrotransposition of Long Interspersed Element-1.2016

    • Author(s)
      Okudaira N, Ishizaka Y, Nishio H, Sakagami H.
    • Journal Title

      IN vivo

      Volume: 30 Pages: 113-118

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Journal Article] Morphine and Fentanyl Citrate Induce Retrotransposition of Long Interspersed Element-1.2016

    • Author(s)
      Okudaira N, Ishizaka Y, Nishio H, Sakagami H.
    • Journal Title

      In Vivo

      Volume: 30 Pages: 113-118

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Presentation] ピラノ[4,3-b]クロモン誘導体の定量的構造‐細胞傷害性相関解析2018

    • Author(s)
      永井純子、史海霞、久保田夕香、坂東健二郎、奥平准之、植沢芳広、坂上宏、友村美根子、友村明人、高尾浩一、杉田義昭
    • Organizer
      第139回日本薬理学会関東部会、東京慈恵会医科大学、東京
    • Data Source
      KAKENHI-PROJECT-16K11519
  • [Presentation] 3-(N-サイクリックアミノ)クロモン誘導体の定量的構造‐細胞傷害性相関解析2018

    • Author(s)
      坂上宏、史 海霞、永井純子、坂詰つかさ、坂東健二郎、奥平 准之、植沢芳広、友村美根子、友村明人、高尾浩一、杉田義昭
    • Organizer
      第139回日本薬理学会関東部会、東京慈恵会医科大学、東京
    • Data Source
      KAKENHI-PROJECT-16K11519
  • [Presentation] Long interspersed element-1 retrotransposition induced by imipramine depends on NR2A.2018

    • Author(s)
      Okudaira N.
    • Organizer
      The 18th World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Presentation] LINE-1 retrotransposition by peroxisome proliferator-activated receptor α inhibited by resveratrol2017

    • Author(s)
      奥平准之、石坂幸人
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Presentation] Involvement of long interspersed element 1 Retrotransposition induced by imipramine.2017

    • Author(s)
      奥平准之、坂上宏
    • Organizer
      第90回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Presentation] 食品成分由来の発がん物質ヘテロサイクリックアミンのレトロトランスポジション2017

    • Author(s)
      奥平准之
    • Organizer
      日本食品免疫学会第13回学術大会(JAFI2017)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Presentation] 体細胞におけるLINE-1レトロトランスポジションの転移機構2017

    • Author(s)
      奥平准之
    • Organizer
      日薬レトロポゾン研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Presentation] フラノクロモン誘導体の定量的構造‐細胞傷害性相関解析2017

    • Author(s)
      植沢芳広、高尾浩一、杉田義、加賀谷肇、奥平准之、坂上宏
    • Organizer
      第138回日本薬理学会関東部会、慶応義塾大学薬学部、東京
    • Data Source
      KAKENHI-PROJECT-16K11519
  • [Presentation] Involvement of long interspersed element 1 Retrotransposition induced by imipramine.2017

    • Author(s)
      奥平准之、坂上宏.
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Presentation] ドキソルビシンのヒト口腔ケラチノサイトに対する傷害性を緩和する物質の探索2016

    • Author(s)
      坂上 宏、奥平准之、天野 修、横瀬敏志
    • Organizer
      第58回歯科基礎医学会総会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-16K11519
  • [Presentation] Analysis of long interspersed element 1 Retrotransposition in various drugs2016

    • Author(s)
      奥平准之、坂上宏
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Presentation] 鎮痛薬のLong Interspersed Element 1転移機構2015

    • Author(s)
      奥平准之、西口美紀、主田英之、大塚洋輔、西尾元
    • Organizer
      第99回日本法医学会
    • Place of Presentation
      高知
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-15K19278
  • [Presentation] 心筋型リアノジン受容体遺伝子変異マウス(RyR2-R420W mice)の病態解析2013

    • Author(s)
      奥平 准之
    • Organizer
      日本法医学会(北海道総会)
    • Place of Presentation
      ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-24890282
  • [Presentation] Mice with the R420W Cardiac Ryanodine Receptor Mutation Exhibit Status Thymicolymphaticus-Like Phenotypes(心筋型リアノジン受容体遺伝子(RyR2)変異マウスの免疫生物学的機能解析)2013

    • Author(s)
      奥平准之、西尾元
    • Organizer
      第36回日本分子生物学会年会演題番号
    • Year and Date
      2013-12-05
    • Data Source
      KAKENHI-PROJECT-24890282
  • [Presentation] 筋型リアノジン受容体遺伝子変異マウス(RyR2-R420W mice)の病態解析2013

    • Author(s)
      奥平准之、森川公子、西口美紀、主田英之、大内晴美、佐藤貴子、鈴木廣一、西尾元心
    • Organizer
      第97次日本法医学会学術全国集会
    • Year and Date
      2013-06-28
    • Data Source
      KAKENHI-PROJECT-24890282
  • [Presentation] 心筋型リアノジン受容体遺伝子変異マウス(RyR2-R420W mice)の病態解析

    • Author(s)
      奥平准之、森川公子、西口美紀、主田英之、大内晴美、佐藤貴子、鈴木廣一、西尾元
    • Organizer
      第97次日本法医学会学術全国集会
    • Place of Presentation
      ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-24890282
  • [Presentation] 心筋型リアノジン受容体遺伝子変異マウス(RyR2-R420W mice)の病態解析

    • Author(s)
      奥平准之、森川公子、西口美紀、主田英之、大内晴美、佐藤貴子、鈴木廣一、西尾元
    • Organizer
      第97次日本法医学会学術全国集会
    • Place of Presentation
      ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-25293164
  • [Presentation] Mice with the R420W Cardiac Ryanodine Receptor Mutation Exhibit Status Thymicolymphaticus-Like Phenotypes

    • Author(s)
      奥平准之、西尾元
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-25293164
  • [Presentation] Mice with the R420W Cardiac Ryanodine Receptor Mutation Exhibit Status Thymicolymphaticus-Like Phenotypes

    • Author(s)
      奥平准之、西尾元
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-24890282
  • 1.  Sakagami Hiroshi (50138484)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 2.  BANDOW KENJIRO (50347093)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 3.  杉田 義昭 (20255029)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 4.  高尾 浩一 (70337484)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 5.  植沢 芳広 (90322528)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 6.  友村 美根子 (30217559)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 7.  天野 滋 (90167958)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  Nishio Hajime (90253260)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  NAGAI JUNKO (50828142)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 10.  杉本 昌弘 (30458963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  須永 克佳 (70236040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  藤内 祝 (50172127)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  光藤 健司 (70303641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  小泉 敏之 (80323575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  中鍛治 里奈 (80845511)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  山本 信治 (60385185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  坂下 英明 (10178551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  田沼 靖一 (10142449)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  佐藤 聡 (40530663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  友村 明人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 21.  加賀谷 肇
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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