Mitsuishi Yoichiro 光石陽一郎

… Alternative Names

光石陽一郎ミツイシヨウイチロウ

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Researcher Number	10647001
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 順天堂大学, 医学部, 助教 2014: 東北大学, 病院, 助教 2013: 東北大学, 高等教育開発推進センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 非小細胞肺癌 / Keap1-Nrf2経路 / 酸化ストレス応答経路 / ゲノム構造多型 / スプライシング異常 / スプライシング / 酸化ストレス経路 / 抗癌剤耐性 / 小細胞肺癌 / Keap1 / 創薬スクリーニング / Nrf2 … More Except Principal Investigator … More エピジェネティクス / シングルセル解析 / 腫瘍内不均一性 / 分化制御異常 / 間葉系幹細胞 / 腫瘍抑制遺伝子 / リンパ脈管筋腫症 / 治療標的 / シングルセルATAC-seq / シングルセルRNA-seq / 細胞老化 / 薬剤耐性 / 胸部悪性腫瘍 / 中皮腫 Less

薬剤耐性クローンに着目した腫瘍内不均一性と薬剤耐性原理の解明
- Principal Investigator
  
  田島健
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
エピジェネティクスの再構成の追跡による老化細胞の分類構築と新規治療法開発への挑戦
- Principal Investigator
  
  田島健
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Juntendo University
リンパ脈管筋腫症は神経堤由来間葉系幹細胞が分化制御異常を来した疾患である
- Principal Investigator
  
  瀬山邦明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
肺癌における酸化ストレス応答系の新規破綻機序の解明と標的治療の探索Principal Investigator
- Principal Investigator
  
  光石陽一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
中皮腫における細胞系譜構築による新規治療法の探究と臨床応用
- Principal Investigator
  
  高橋和久
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
小細胞肺癌における酸化ストレス応答系の破綻機序の解明Principal Investigator
- Principal Investigator
  
  光石陽一郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
非小細胞肺癌を標的とするNrf2阻害剤の開発Principal Investigator
- Principal Investigator
  
  光石陽一郎
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University

All 2023 2022 2021 2015 2014

All Journal Article Presentation Book

[Book] Annual Review 呼吸器 20152015
- Author(s)
  永井厚志、光石陽一郎、本橋ほづみ
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25860634
[Book] Annual Review 呼吸器 20142014
- Author(s)
  永井厚志、光石陽一郎
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25860634
[Journal Article] Early Detection of Therapeutic Benefit from PD-1/PD-L1 Blockade in Advanced Lung Cancer by Monitoring Cachexia-Related Circulating Cytokines2023
- Author(s)
  Xu Shiting、Miura Keita、Shukuya Takehito、Harada Sonoko、Fujioka Masahiro、Winardi Wira、Shimamura Shoko、Kurokawa Kana、Sumiyoshi Issei、Miyawaki Taichi、Asao Tetsuhiko、Mitsuishi Yoichiro、Tajima Ken、Takahashi Fumiyuki、Hayashi Takuo、Harada Norihiro、Takahashi Kazuhisa
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 4 Pages: 1170-1170
- DOI
  10.3390/cancers15041170
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08524, KAKENHI-PROJECT-19K23978, KAKENHI-PROJECT-21K08187
[Journal Article] A Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer2022
- Author(s)
  Kawamura Kodai,Matsushima Hidekazu,Sakai Hiroshi,Iwashima Akira,Nakamura Sukeyuki,Kojima Tohru,Sasaki Shinichi,Shigenaga Takehiko,Natsume Ichiro,Sasaki Takaaki,Ohsaki Yoshinobu,Iwanaga Kentaro,Nishi Koichi,Mitsuishi Yoichiro,Taniguchi Hirokazu,Sato Kazuhiro,Yamauchi Mitsugu,Nakajima Motowo,Takahashi Kazuhisa
- Journal Title
  
  Oncology
  
  Volume: 100 Issue: 11 Pages: 620-632
- DOI
  10.1159/000526977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08524
[Journal Article] Survival past five years with advanced, EGFR-mutated or ALK-rearranged non-small cell lung cancer?is there a “tail plateau” in the survival curve of these patients?2022
- Author(s)
  Shimamura Shoko Sonobe、Shukuya Takehito、Asao Tetsuhiko、Hayakawa Daisuke、Kurokawa Kana、Xu Shiting、Miura Keita、Mitsuishi Yoichiro、Tajima Ken、Shibayama Rina、Shimada Naoko、Takahashi Fumiyuki、Takahashi Kazuhisa
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 323-323
- DOI
  10.1186/s12885-022-09421-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08524, KAKENHI-PROJECT-21K08187
[Journal Article] Clinical characteristics of adrenal insufficiency induced by pembrolizumab in non‐small‐cell lung cancer2022
- Author(s)
  Kurokawa Kana、Mitsuishi Yoichiro、Shimada Naoko、Ito Naoaki、Ogiwara Misa、Miura Keita、Asao Tetsuhiko、Ko Ryo、Shukuya Takehito、Shibayama Rina、Goto Hiromasa、Takahashi Kazuhisa
- Journal Title
  
  Thoracic Cancer
  
  Volume: 14 Issue: 5 Pages: 442-449
- DOI
  10.1111/1759-7714.14761
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08524
[Journal Article] Association between the efficacy and immune-related adverse events of pembrolizumab and chemotherapy in non-small cell lung cancer patients: a retrospective study2022
- Author(s)
  Kurokawa Kana、Mitsuishi Yoichiro、Shimada Naoko、Kawakami Yuta、Miura Keita、Miyawaki Taichi、Asao Tetsuhiko、Ko Ryo、Shukuya Takehito、Shibayama Rina、Nojiri Shuko、Takahashi Kazuhisa
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 1047-1047
- DOI
  10.1186/s12885-022-10133-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08524
[Journal Article] A Novel Therapeutic Strategy Targeting the Mesenchymal Phenotype of Malignant Pleural Mesothelioma by Suppressing LSD12021
- Author(s)
  Wirawan Aditya、Tajima Ken、Takahashi Fumiyuki、Mitsuishi Yoichiro、Winardi Wira、Hidayat Moulid、Hayakawa Daisuke、Matsumoto Naohisa、Izumi Kenta、Asao Tetsuhiko、Ko Ryo、Shimada Naoko、Takamochi Kazuya、Suzuki Kenji、Abe Masaaki、Hino Okio、Sekido Yoshitaka、Takahashi Kazuhisa
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 20 Issue: 1 Pages: 127-138
- DOI
  10.1158/1541-7786.mcr-21-0230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03527, KAKENHI-PROJECT-20K08524, KAKENHI-PROJECT-21K08187
[Presentation] Approaches to Malignant Pleural Mesothelioma by Targeting Epigenetic Modifiers2023
- Author(s)
  Ken Tajima、Yosuke Miyashita、Aditya Wirawan、Kenta Izumi、Naohisa Matsumoto、Yoichiro Mitsuishi、Yasushi Okazaki、Kazuhisa Takahashi
- Organizer
  第82回日本癌学会学術総会　Symposia on Specific Tumors/腫瘍別シンポジウム2
- Data Source
  KAKENHI-PROJECT-23K21435
[Presentation] Approaches to Malignant Pleural Mesothelioma by Targeting Epigenetic Modifiers2023
- Author(s)
  Ken Tajima、Yosuke Miyashita、Aditya Wirawan、Kenta Izumi、Naohisa Matsumoto、Yoichiro Mitsuishi、Yasushi Okazaki、Kazuhisa Takahashi
- Organizer
  第82回日本癌学会学術総会 Symposia on Specific Tumors/腫瘍別シンポジウム2
- Data Source
  KAKENHI-PROJECT-23K27465
[Presentation] 非小細胞肺癌における抗ミュラー管ホルモン2型受容体（AMHR2）の発現と細胞増殖における役割の検討．2022
- Author(s)
  濃沼淑芳，光石陽一郎，高橋史行，Wira Winardi，金森幸一郎，林大久生，高持一矢，鈴木健司，高橋和久
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] Outcomes associated with immune-related adverse events in non-small cell lung cancer treated with pembrolizumab plus chemotherapy2022
- Author(s)
  K Kurokawa, Y Mitsuishi, N Shimada, K Miura, T Miyawaki, T Asao, R Ko, T Shukuya, R Shibayama, K Takahashi
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] Efficacy and safety of the transbronchial lung cryobiopsy: a single-center retrospective study in Japan.2022
- Author(s)
  T Nishimaki, K Kurokawa, T Miyawaki, T Asao, R Kanemaru, T Mimori, S Kuriyama, Y Mitsuishi, M Ichikawa, N Shimada, T Hayashi, K Takahashi.
- Organizer
  The 26th Congress of the Asian Pacific Society of Respirology(APSR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] 免疫チェックポイント阻害剤（ICI）による肺障害を呈した肺癌患者へのステロイド投与に関する後方視的検討．2022
- Author(s)
  大熊智子，三森友靖，宿谷威仁，増田孝一，三浦啓太，黒川加奈，早川乃介，徐仁美，宮脇太一，朝尾哲彦，金丸良太，光石陽一郎，嶋田奈緒子，田島健，高橋和久
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08524
[Presentation] Efficacy and safety of the transbronchial lung cryobiopsy: a single-center retrospective study in Japan.2022
- Author(s)
  Y Nagata, T Nagaoka, Y Kuroda, S Hotta, T Okuma, K Masuda, N Sakamoto, T Nishimaki, K Kurokawa, T Miyawaki, T Asao , R Kanemaru, T Mimori, S Kuriyama, Y Mitsuishi, M Ichikawa, N Shimada, T Hayashi, K Takahashi.
- Organizer
  The 26th Congress of the Asian Pacific Society of Respirology(APSR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08524

1. 高橋和久 (80245711)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
2. 田島健 (50384102)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. 高橋史行 (70327823)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 白石友一 (70516880)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 鈴木健司 (10415523)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 柳下薫寛 (80781674)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 林大久生 (70569128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 高遼 (60795178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 眞鍋理一郎 (30280837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岡崎康司 (80280733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 瀬山邦明 (10226681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 新井田要 (40293344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 関戸好孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mitsuishi Yoichiro 光石 陽一郎

光石 陽一郎 ミツイシ ヨウイチロウ

Research Projects

Research Products

Co-Researchers

薬剤耐性クローンに着目した腫瘍内不均一性と薬剤耐性原理の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エピジェネティクスの再構成の追跡による老化細胞の分類構築と新規治療法開発への挑戦

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

リンパ脈管筋腫症は神経堤由来間葉系幹細胞が分化制御異常を来した疾患である

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺癌における酸化ストレス応答系の新規破綻機序の解明と標的治療の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

中皮腫における細胞系譜構築による新規治療法の探究と臨床応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

小細胞肺癌における酸化ストレス応答系の破綻機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非小細胞肺癌を標的とするNrf2阻害剤の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Annual Review 呼吸器 20152015

Author(s)

Publisher

Data Source

[Book] Annual Review 呼吸器 20142014

Author(s)

Publisher

Data Source

[Journal Article] Early Detection of Therapeutic Benefit from PD-1/PD-L1 Blockade in Advanced Lung Cancer by Monitoring Cachexia-Related Circulating Cytokines2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Survival past five years with advanced, EGFR-mutated or ALK-rearranged non-small cell lung cancer?is there a “tail plateau” in the survival curve of these patients?2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical characteristics of adrenal insufficiency induced by pembrolizumab in non‐small‐cell lung cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between the efficacy and immune-related adverse events of pembrolizumab and chemotherapy in non-small cell lung cancer patients: a retrospective study2022

Author(s)

Journal Title

DOI

Data Source

Mitsuishi Yoichiro 光石陽一郎

光石陽一郎ミツイシヨウイチロウ