Mano Yohei 間野洋平

… Alternative Names

MANO yohei 間野洋平

Less

Researcher Number	10792244
Affiliation (Current)	2025: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help	2023: 九州大学, 医学研究院, 共同研究員 2019 – 2023: 独立行政法人国立病院機構(九州がんセンター臨床研究センター), その他部局等, 肝胆膵外科医師 2018 – 2020: 九州大学, 大学病院, 助教 2017: 九州大学, 医学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Digestive surgery
Keywords	Principal Investigator 癌関連線維芽細胞 / 肝細胞癌 / 癌微小環境 / サルコペニア / 膵癌 / エクソソーム / 微小環境 / 線維化 / 腫瘍免疫 / 線維芽細胞 / 肝線維化 / 肝癌 … More Except Principal Investigator … More 肝細胞癌 / 肝移植 / 生体肝移植 / 肝がん / ゲノミクス / 免疫微小環境 / ウイルス学的著効 / mRNAシークエンス / メチル化シークエンス / C型肝炎 / C型肝炎治癒 / 転写因子 / エピゲノム / 線維芽細胞 / EMT / マイクロアレイ解析 / Normal fibroblast / 網羅的解析 / Exsome / CAF / miR-150-3p / miRNA / 癌関連線維芽細胞 / エクソソーム / 分子機序 / 肝性脳症 / 肝不全 / 門脈圧亢進症 / 肝硬変 / メタボローム解析 / 便移植 / 胆汁酸 / 短鎖脂肪酸 / 腸内細菌叢 / マイトファジー / 肝癌 / オートファジー / VETC / 類洞様血管構造 / 膵癌 / capicua / 再発 / HLA-Class II / HLA / HBVワクチン / ワクチン / B型肝炎ウイルス / 創薬 / プロテオーム / Sphere / 化合物ライブラリー / 造血幹細胞 / がん幹細胞 / 集学的治療 / Type IVcollagen / plasma fibronectin / 腹膜播種 / sphere / シグナル伝達 / トランスレーショナルリサーチ / 薬剤反応性 / 細胞・組織 / 外科 / 癌 Less

癌微小環境とサルコペニアの連関をターゲットとした革新的な膵癌治療法の探索Principal Investigator
- Principal Investigator
  
  間野洋平
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
  National Hospital Organization, Kyushu Cancer Center
Genomics analysis of immune microenvironmental changes in hepatocarcinogenesis after cure of hepatitis C
- Principal Investigator
  
  Sugimachi Keishi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  National Hospital Organization, Kyushu Cancer Center
Cancer-associated fibroblasts promote hepatocellular carcinoma progression by exosomePrincipal Investigator
- Principal Investigator
  
  Mano Yohei
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  National Hospital Organization, Kyushu Cancer Center
Prevention of HBV recurrence by HBV vaccination based on SNP and allele of HLA class II
- Principal Investigator
  
  YOSHIZUMI Tomoharu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
肝移植後肝細胞癌再発に対する機序解明と革新的治療戦略の構築
- Principal Investigator
  
  吉屋匠平
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
Autophagy and mitophagy in advanced hepatocellular carcinoma
- Principal Investigator
  
  Ikegami Toru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
  Kyushu University
Elucidation of the molecular mechanism of hepatic encephalopathy and development of innovative treatment by intestinal bacterial flora profiling
- Principal Investigator
  
  soejima yuji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Shinshu University
  Kyushu University
New strategy of hepatocellular carcinoma treatment using exosomes exocrimned by cancer associated fibroblast
- Principal Investigator
  
  HARADA Noboru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
Interaction between cancer associated fibroblasts and immune cells in tumor microenvironment of HCCPrincipal Investigator
- Principal Investigator
  
  MANO yohei
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells
- Principal Investigator
  
  Maehara Yoshihiko
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukuoka Dental College
  Kyushu University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Cachexia index as a prognostic predictor after resection of pancreatic ductal adenocarcinoma2023
- Author(s)
  Tomonari Shimagaki, Keishi Sugimachi, Yohei Mano, Emi Onishi, Tomohiro Iguchi, Yuichiro Nakashima, Masahiko Sugiyama, Manabu Yamamoto, Masaru Morita, Yasushi Toh
- Journal Title
  
  Annals of Gastroenterological Surgery
  
  Volume: 7 Issue: 6 Pages: 977-986
- DOI
  10.1002/ags3.12686
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08884, KAKENHI-PROJECT-22K08908
[Journal Article] Persistent epigenetic alterations in transcription factors after a sustained virological response in hepatocellular carcinoma2022
- Author(s)
  Sugimachi Keishi、Araki Hiromitsu、Saito Hideyuki、Masuda Takaaki、Miura Fumihito、Inoue Kentaro、Shimagaki Tomonari、Mano Yohei、Iguchi Tomohiro、Morita Masaru、Toh Yasushi、Yoshizumi Tomoharu、Ito Takashi、Mimori Koshi
- Journal Title
  
  JGH Open
  
  Volume: 6 Issue: 12 Pages: 854-863
- DOI
  10.1002/jgh3.12833
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08745, KAKENHI-PROJECT-20K08960, KAKENHI-PROJECT-23K24164
[Journal Article] Cancer-associated fibroblasts promote hepatocellular carcinoma progression through downregulation of exosomal miR-150-3p2021
- Author(s)
  Yugawa Kyohei、Yoshizumi Tomoharu、Mano Yohei、Itoh Shinji、Harada Noboru、Ikegami Toru、Kohashi Kenichi、Oda Yoshinao、Mori Masaki
- Journal Title
  
  European Journal of Surgical Oncology
  
  Volume: 47 Issue: 2 Pages: 384-393
- DOI
  10.1016/j.ejso.2020.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08707, KAKENHI-PROJECT-19K18092
[Journal Article] Simultaneous splenectomy improves outcomes after adult living donor liver transplantation.2021
- Author(s)
  Yoshizumi T, Itoh S, Shimokawa M, Inokuchi S, Harada N, Takeishi K, Mano Y, Yoshiya S, Kurihara T, Nagao Y, Ikegami T, Soejima Y, Mori M.
- Journal Title
  
  J Hepatol.
  
  Volume: 74(2) Issue: 2 Pages: 372-379
- DOI
  10.1016/j.jhep.2020.08.017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12693, KAKENHI-PROJECT-19K20676, KAKENHI-PROJECT-18K08542, KAKENHI-PROJECT-21K08718
[Journal Article] Bone morphogenetic protein 4 provides cancer-supportive phenotypes to liver fibroblasts in patients with hepatocellular carcinoma2019
- Author(s)
  Mano Y, Yoshio S, Shoji H, Tomonari S, Aoki Y, Aoyanagi N, Okamoto T, Matsuura Y, Osawa Y, Kimura K, Yugawa K, Wang H, Oda Y, Yoshizumi T, Maehara Y, Kanto T
- Journal Title
  
  J Gastroenterol
  
  Volume: Epub ahead of print Issue: 11 Pages: 1007-1018
- DOI
  10.1007/s00535-019-01579-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19382, KAKENHI-PROJECT-17K16559, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429
[Journal Article] Lymphocyte-to-Monocyte Ratio Is a Predictor of Survival After Liver Transplantation for Hepatocellular Carcinoma.2018
- Author(s)
  Mano Y, Yoshizumi T, Yugawa K, Ohira M, Motomura T, Toshima T, Itoh S, Harada N, Ikegami T, Soejima Y, Maehara Y.
- Journal Title
  
  Liver Transpl.
  
  Volume: 24 Issue: 11 Pages: 1603-1611
- DOI
  10.1002/lt.25204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08647
[Presentation] 膵癌患者における周術期体組成・運動機能変化の意義2023
- Author(s)
  間野洋平、杉町圭史、島垣智成、大西惠美、藤本禎明、財津瑛子、杉山雅彦、中島雄一郎、山本学、森田勝、藤也寸志
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-22K08884
[Presentation] 高齢者膵癌症例に対する手術療法の短期・長期成績と高齢者機能評価の意義2023
- Author(s)
  意義間野洋平　杉町圭史　島垣智成　大西惠美　藤本禎明　財津瑛子　杉山雅彦　中島雄一郎山本学　森田勝　藤也寸志
- Organizer
  第78回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-22K08884
[Presentation] Sustained epigenetic carcinogenic alteration in hepatocellular carcinoma arising on the liver after viral eradication2023
- Author(s)
  Keishi Sugimachi, Tomonari Shimagaki, Yohei Mano, Emi Onishi, Masaru Morita, Yasushi Toh, Koshi Mimori
- Organizer
  Society of Surgical Oncology 2023 International Conference on Surgical Cancer Care
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08745
[Presentation] 全ゲノム的メチローム・トランスクリプトーム解析によるSVR後肝発癌関連転写因子の同定2022
- Author(s)
  杉町圭史、間野洋平、島垣智成、大西惠美、増田隆明、藤本禎明、上原英雄、中島雄一郎、杉山雅彦、山本学、森田勝、三森功士、藤也寸志
- Organizer
  第122回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K08745
[Presentation] 肝癌微小環境における癌関連線維芽細胞由来エクソソームの意義2020
- Author(s)
  湯川恭平, 吉住朋晴, 間野洋平, 伊勢田憲史, 冨山貴央, 森永哲成, 小斎侑希子, 井口詔一, 吉屋匠平, 武石一樹, 戸島剛男, 長尾吉泰, 伊藤心二, 原田昇, 池上徹, 森正樹
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08647
[Presentation] 肝癌微小環境における癌関連線維芽細胞由来エクソソームの意義2020
- Author(s)
  湯川恭平, 吉住朋晴, 間野洋平, 伊勢田憲史, 冨山貴央, 森永哲成, 小斎侑希子, 井口詔一, 吉屋匠平, 武石一樹, 戸島剛男, 長尾吉泰, 伊藤心二, 原田昇, 池上徹, 森正樹
- Organizer
  第120回日本外科学科定期学術集会
- Data Source
  KAKENHI-PROJECT-19K18092
[Presentation] 膵癌における転写抑制因子capicua発現の意義の検討2019
- Author(s)
  吉屋匠平、吉住朋晴、伊勢田憲史、冨山貴央、森永哲成、湯川恭平、小斉侑希子、井口詔一、栗原　健、間野洋平、武石一樹、伊藤心二、原田　昇、池上　徹、副島雄二、森　正樹
- Organizer
  JDDW2019 KOBE
- Data Source
  KAKENHI-PROJECT-18K08619
[Presentation] 肝細胞癌における癌関連線維芽細胞の役割2019
- Author(s)
  マノヨウヘイ
- Organizer
  第30回消化器癌発生学会
- Data Source
  KAKENHI-PROJECT-19K18092
[Presentation] 浸潤性膵管癌における転写抑制因子capicua発現の意義の検討2019
- Author(s)
  吉屋匠平、吉住朋晴、栗原　健、間野洋平、武石一樹、伊藤心二、原田　昇、池上　徹、副島雄二
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08619
[Presentation] The impact of capicua (CIC) expression on pancreatic ductal adenocarcinoma2019
- Author(s)
  Shohei Yoshiya, Tomoharu Yoshizumi, Takeshi Kurihara, Yohei Mano, Kazuki Takeishi, Shinji Itoh, Noboru Harada, Toru Ikegami, Yuji Soejima, Masaki Mori
- Organizer
  The 31th Meeting of Japanese Society pf Hepato-Biliary-Pancreatic Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08619
[Presentation] 肝癌関連線維芽細胞におけるBMP4の機能と意義2018
- Author(s)
  間野洋平　吉住朋晴　　考藤達哉
- Organizer
  第26回日本消化器関連学会週間（JDDW2018KOBE）
- Data Source
  KAKENHI-PROJECT-17K16559

1. YOSHIZUMI Tomoharu (80363373)

# of Collaborated Projects: 8 results

# of Collaborated Products: 7 results
2. soejima yuji (30325526)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
3. HARADA Noboru (80419580)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
4. Ikegami Toru (80432938)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
5. 本村貴志 (50719507)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
6. 伊藤心二 (90382423)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
7. 戸島剛男 (40608965)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
8. Sugimachi Keishi (90452763)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
9. 吉屋匠平 (20717079)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. Maehara Yoshihiko (80165662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 播本憲史 (00419582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 古山正 (00419590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 原田結 (00608507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 馬場秀夫 (20240905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 赤星朋比古 (20336019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松本拓也 (20374168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 飯森真人 (20546460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 安藤幸滋 (20608864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 北尾洋之 (30368617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 森崎浩一 (30625801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 豊川剛二 (30627261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 吉野一郎 (40281547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 米満吉和 (40315065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中島雄一郎 (40733564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 杉山雅彦 (40751079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 池田哲夫 (60585701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 調憲 (70264025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 相島慎一 (70346774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 武冨紹信 (70363364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 沖英次 (70380392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 内山秀昭 (70380425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 掛地吉弘 (80284488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 佐伯浩司 (80325448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 岡本龍郎 (80568626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 木村光一 (80755273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 田川哲三 (90419557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 庄司文裕 (90444851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 中西良太 (90771254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 工藤健介 (90801663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 岡野慎士 (10380429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 堤亮介 (60846541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 橋本直隆 (30608964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 山下奈真 (60608967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 久保信英 (20811748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 諸富洋介 (60645365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 安田光宏 (90269043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 西田奈央 (50456109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. 後町武志 (40338893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 古川賢英 (80624973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 白井祥睦 (10785364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 恩田真二 (10459620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. 長尾吉泰 (70608968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
53. 増田隆明 (50463493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
54. 荒木啓充 (60572823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. 由雄祥代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mano Yohei 間野 洋平

MANO yohei 間野 洋平

Research Projects

Research Products

Co-Researchers

癌微小環境とサルコペニアの連関をターゲットとした革新的な膵癌治療法の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genomics analysis of immune microenvironmental changes in hepatocarcinogenesis after cure of hepatitis C

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cancer-associated fibroblasts promote hepatocellular carcinoma progression by exosomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prevention of HBV recurrence by HBV vaccination based on SNP and allele of HLA class II

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝移植後肝細胞癌再発に対する機序解明と革新的治療戦略の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Autophagy and mitophagy in advanced hepatocellular carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism of hepatic encephalopathy and development of innovative treatment by intestinal bacterial flora profiling

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New strategy of hepatocellular carcinoma treatment using exosomes exocrimned by cancer associated fibroblast

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Interaction between cancer associated fibroblasts and immune cells in tumor microenvironment of HCCPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cachexia index as a prognostic predictor after resection of pancreatic ductal adenocarcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Persistent epigenetic alterations in transcription factors after a sustained virological response in hepatocellular carcinoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cancer-associated fibroblasts promote hepatocellular carcinoma progression through downregulation of exosomal miR-150-3p2021

Author(s)

Journal Title

DOI

Data Source

Mano Yohei 間野洋平

MANO yohei 間野洋平