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0 0  白井 祥睦

… Alternative Names

Shirai Yoshihiro  白井 祥睦

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Researcher Number 10785364
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-4907-0101
Affiliation (Current) 2022: 東京慈恵会医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2016 – 2021: 東京慈恵会医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Digestive surgery / Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords
Principal Investigator
膵臓癌 / オートファジー / 酸性αグルコシダーゼ / 抗癌剤耐性 / ライソゾーム / Lysosome / 酸性さらみだーぜ / アデノウイルスベクター / 遺伝子治療 / スフィンゴリン脂質 / ライソゾーム酵素 … More
Except Principal Investigator
… More オートファジー / マイトファジー / 肝細胞癌 / 癌微小環境 / 膵臓癌 / 肝虚血再灌障害 / アポトーシス / 肝虚血再灌流障害 / ミトコンドリア / Parkin / アデノウイルスベクター / miRNA / エクソソーム / 化学療法抵抗性 / 腸内細菌 / 腫瘍免疫 / ライソゾーム / 肝癌 Less
  • Research Projects

    (7 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (19 People)
  •  The molecular mechanism of hepatocellular carcinoma associated fibroblast oriented exosome miRNA

    • Principal Investigator
      Ikegami Toru
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  腸内細菌による膵臓癌化学療法抵抗性の機序解明と革新的治療法開発

    • Principal Investigator
      春木 孝一郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  膵癌特異的エネルギー代謝メカニズムに基づく革新的治療の開発

    • Principal Investigator
      宇和川 匡
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  Analysis of lysosomal metabolism in pancreatic cancerPrincipal Investigator

    • Principal Investigator
      白井 祥睦
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  Autophagy and mitophagy in advanced hepatocellular carcinoma

    • Principal Investigator
      Ikegami Toru
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
      Kyushu University
  •  Analysis of lysosome in pancreatic cancerPrincipal Investigator

    • Principal Investigator
      Shirai Yoshihiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Jikei University School of Medicine
  •  Parkin-dependent mitophagy in hepatic ischemia-reperfusion injury

    • Principal Investigator
      Yanaga Katsuhiko
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Jikei University School of Medicine

All 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Small-for-size graft, small-for-size syndrome and inflow modulation in living donor liver transplantation.2020

    • Author(s)
      Ikegami T, Onda S, Furukawa K, Haruki K, Shirai Y, Gocho T
    • Journal Title

      J Hepatobiliary Pancreat Sci.

      Volume: 27 Pages: 799-809

    • DOI

      10.1002/jhbp.822

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08647
  • [Presentation] 膵臓癌に対するLysosome酵素制御によるTFEB抑制を介した抗腫瘍効果誘導の試み2021

    • Author(s)
      羽村凌雅、白井祥睦、谷合智彦、柳垣充、斉藤庸博、堀内尭、高田直樹、嶋田洋太、鐘ヶ江裕美、大橋十也、矢永勝彦
    • Organizer
      第51回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-20K17665
  • [Presentation] スフィンゴリン脂質代謝に着目した膵臓がんに対する抗腫瘍効果の検討2020

    • Author(s)
      谷合智彦、池上徹、矢永勝彦、白井祥睦、柳垣充、羽村凌雅、高田直樹、堀内尭、嶋田洋太、後町武志、柴浩明、大橋十也、大木隆生
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-20K17665
  • [Presentation] 大腸癌肝転移肝切除における外科感染症のリスク因子の検討と長期予後改善を目指した対策2020

    • Author(s)
      古川 賢英, 後町 武志, 谷合 智彦, 柳垣 充, 羽村 凌雅, 堀内 尭, 白井 祥睦, 安田 淳吾, 春木 孝一郎, 塩崎 弘憲, 恩田 真二, 池上 徹
    • Organizer
      第82回日本臨床外科学会総会
    • Data Source
      KAKENHI-PROJECT-18K08647
  • [Presentation] ライソゾーム酵素による膵臓癌におけるオートファジー調整機構の解明2020

    • Author(s)
      羽村凌雅、白井祥睦、谷合智彦、柳垣充、高田直樹、堀内尭、嶋田洋太、鐘ヶ江裕美、大橋十也、池上徹
    • Organizer
      第31回消化器癌発生学会
    • Data Source
      KAKENHI-PROJECT-20K17665
  • [Presentation] Inhibition of sphingolipid metabolism has ceramide-induced anti-tumor effect on pancreatic cacner cells2020

    • Author(s)
      Tomohiko Taniai, Yoshihiro Shirai, Yohta Shimada, Ryoga Hamura, Mitsuru Yanagaki, Naoki Takada, Kazuhito Tsuboi, Yasuo Okamoto, Toya Ohashi, Katsuhiko Yanaga, Toru Ikegami
    • Organizer
      American Collage of Surgeons (ACS) clinical congress 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17665
  • [Presentation] 抗癌剤耐性膵癌におけるライソソーム酵素の機能解析と遺伝子制御による塩酸ゲムシタビンの抗腫瘍効果増強の試み2019

    • Author(s)
      羽村凌雅, 矢永勝彦, 白井祥睦, 谷合 智彦, 斉藤庸博, 嶋田洋太, 堀内 尭, 菅野 宏, 高田直樹, 鐘ヶ江裕美, 大橋十也, 大木隆生.
    • Organizer
      第119回 日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K16584
  • [Presentation] Down-regulation of acid-α glucosidase induce antitumor effect via mitochondrial dysfunction in pancreatic cancer cell2019

    • Author(s)
      Ryoga Hamura, Yoshihiro Shirai, Nobuhiro Saito, Tomohiko Taniai, Yohta Shimada, Takashi Horiuchi, Hiroshi Sugano, Naoki Takada, Yumi Kanegae, Toya Ohashi, Katsuhiko Yanaga
    • Organizer
      第78回 日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K16584
  • [Presentation] 抗癌剤耐性膵癌におけるライソソーム酵素の機能解析と遺伝子制御による塩酸ゲムシタビンの抗腫瘍効果増強の試み2019

    • Author(s)
      羽村凌雅, 矢永勝彦, 白井祥睦, 谷合 智彦, 斉藤庸博, 嶋田洋太, 堀内 尭, 菅野 宏, 高田直樹, 鐘ヶ江裕美, 大橋十也, 大木隆生
    • Organizer
      第119回 日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K16584
  • [Presentation] Inhibition of lysosomal enzyme activity enhances antitumor effect of gemcitabine in pancreatic cancer cells.2019

    • Author(s)
      Ryoga Hamura, Yoshihiro Shirai, Nobuhiro Saito, Tomohiko Taniai, Yohta Shimada, Takashi Horiuchi, Hiroshi Sugano, Naoki Takada, Yumi Kanegae, Toya Ohashi, Katsuhiko Yanaga
    • Organizer
      14th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16584
  • [Presentation] Parkin-dependent mitophagy in hepatic ischemia-reperfusion injury2019

    • Author(s)
      白井祥睦
    • Organizer
      第31回日本肝胆膵外科学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K10173
  • [Presentation] Inhibition of lysosomal enzyme activity enhances antitumor effect of gemcitabine in pancreatic cancer cells.2019

    • Author(s)
      Hamura R, Shirai Y, Saito N, Taniai T, Shimada Y, Horiuchi T, Sugano H, Takada N, Kanegae Y, Ohashi T, Yanaga K.
    • Organizer
      14th Annual Academic Surgical Congress (ASC)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16584
  • [Presentation] Inhibition of acid ceramidase enhances antitumor effect of gemcitabine on pancreatic cancer cells2019

    • Author(s)
      Tomohiko Taniai, Yoshihiro Shirai, Ryoga Hamura, Takashi Horiuchi, Nobuhiro Saito, Mitsuru Yanagaki, Yohta Shimada, Naoki Takada, Toya Ohashi, Katsuhiko Yanaga
    • Organizer
      第78回 日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K16584
  • [Presentation] Suppression of lysosomal enzyme improves chemoresistance in pancreatic cancer cells.2018

    • Author(s)
      Hamura R, Shirai Y, Saito N, Taniai T, Shimada Y, Horiuchi T, Sugano H, Takada N, Kanegae Y, Ohashi T, Yanaga K
    • Organizer
      第77回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K16584
  • 1.  Ikegami Toru (80432938)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 2.  後町 武志 (40338893)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  恩田 真二 (10459620)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 4.  古川 賢英 (80624973)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 5.  春木 孝一郎 (60720894)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  田中 真二 (30253420)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  阿部 恭平 (30751292)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  Yanaga Katsuhiko (70220176)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  安田 淳吾 (90896870)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  塩崎 弘憲 (30896816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  須田 亙 (20590847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  宇和川 匡 (70287209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  間野 洋平 (10792244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  副島 雄二 (30325526)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  戸島 剛男 (40608965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  本村 貴志 (50719507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  吉住 朋晴 (80363373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  原田 昇 (80419580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  伊藤 心二 (90382423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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