Yanagaki Mitsuru 柳垣充

Researcher Number	80979435
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2023 – 2025: 東京慈恵会医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator エクソソーム / 微小環境 / 血管内皮細胞 / 肝細胞癌 Except Principal Investigator 肝細胞癌 / 癌微小環境 / オートファジー / 膵臓癌 / 血管新生阻害薬 / microRNA … More / エクソソーム / 血管内皮細胞 / 癌免疫 / レンバチニブ / 薬剤耐性 / 分子標的薬 / マイトファジー / レンバチニブ耐性 / リキッドバイオプシー / 獲得耐性メカニズム / ミトコンドリア / ライソゾーム / 肝癌 / GPR15 / MHCクラスI / 腫瘍免疫 / 免疫回避機構 / Lysosome酵素 Less

肝癌におけるGPR15の分子生物学的機能解明および革新的癌免疫療法の開発
- Principal Investigator
  
  堀内尭
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Jikei University School of Medicine
肝細胞癌におけるライソゾームとミトコンドリアの関連に注目した革新的治療法の開発
- Principal Investigator
  
  坂本太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
Elucidation of mechanisms of chemotherapy resistance through epigenetic analysis of pancreatic cancer and development of innovative treatment methods
- Principal Investigator
  
  宇和川匡
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
癌微小環境に着目した肝細胞癌の分子標的薬耐性メカニズム解明と革新的治療法の開発
- Principal Investigator
  
  恩田真二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
肝細胞癌の宿主免疫回避機構の解明に基づく新たな治療戦略の開発
- Principal Investigator
  
  池上徹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
肝癌微小環境における癌関連血管内皮細胞の分子生物学的機能解明と革新的治療法開発
- Principal Investigator
  
  春木孝一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
肝癌血管内皮細胞由来エクソソームを介した癌進展メカニズムの解明と革新的治療法開発Principal Investigator
- Principal Investigator
  
  柳垣充
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
Analysis of lysosome enzymes in pancreatic cancer specific immune evasion system
- Principal Investigator
  
  白井祥睦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
  University of Toyama

All 2024 2023

All Journal Article Presentation

[Journal Article] Analysis of Preoperative Risk Factors for Early Recurrence in Patients After Hepatic Resection for Intrahepatic Cholangiocarcinoma2024
- Author(s)
  Akaoka Munetoshi、Haruki Koichiro、Furukawa Kenei、Tsunematsu Masashi、Ishizaki Shunta、Okui Norimitsu、Shirai Yoshihiro、Yanagaki Mitsuru、Onda Shinji、Ikegami Toru
- Journal Title
  
  The American Surgeon
  
  Volume: 90 Issue: 6 Pages: 1148-1155
- DOI
  10.1177/00031348241227173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K11920
[Journal Article] Short-term Outcomes of Laparoscopic<i>Versus</i>Open Liver Resection in the Elderly: A Propensity Score-matched Analysis2024
- Author(s)
  IGARASHI YOSUKE、HARUKI KOICHIRO、FURUKAWA KENEI、TANIAI TOMOHIKO、YANAGAKI MITSURU、OKUI NORIMITSU、SHIRAI YOSHIHIRO、TSUNEMATSU MASASHI、SAKAMOTO TARO、IKEGAMI TORU
- Journal Title
  
  Anticancer Research
  
  Volume: 44 Issue: 6 Pages: 2731-2736
- DOI
  10.21873/anticanres.17081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K11920
[Journal Article] Proposal for Prognosis-Oriented Definition of Borderline Resectable Hepatocellular Carcinoma.2024
- Author(s)
  Haruki K, Harimoto N, Furukawa K, Taniai T, Yanagaki M, Igarashi Y, Tsunematsu M, Shirai Y, Shirabe K, Ikegami T
- Journal Title
  
  J Am Coll Surg.
  
  Volume: 238 Issue: 6 Pages: 1137-1147
- DOI
  10.1097/xcs.0000000000001032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K11898, KAKENHI-PROJECT-24K11920
[Journal Article] The postoperative platelet-to-lymphocyte ratio predicts the outcome of patients undergoing pancreaticoduodenectomy for pancreatic head cancer2023
- Author(s)
  Shirai Yoshihiro、Hamura Ryoga、Tanji Yoshiaki、Taniai Tomohiko、Yanagaki Mitsuru、Haruki Koichiro、Furukawa Kenei、Onda Shinji、Sakamoto Taro、Gocho Takeshi、Ikegami Toru
- Journal Title
  
  Surgery Today
  
  Volume: 54 Issue: 3 Pages: 247-257
- DOI
  10.1007/s00595-023-02727-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08202
[Journal Article] Superior mesenteric vein/portal vein contact in preoperative imaging indicates biological malignancy in anatomically resectable pancreatic cancer2023
- Author(s)
  Shirai Yoshihiro、Onda Shinji、Tanji Yoshiaki、Hamura Ryoga、Matsumoto Michinori、Yanagaki Mitsuru、Tsunematsu Masashi、Taniai Tomohiko、Haruki Kochiro、Furukawa Kenei、Abe Kyohei、Sakamoto Taro、Gocho Takeshi、Uwagawa Tadashi、Ikegami Toru
- Journal Title
  
  Surgical Oncology
  
  Volume: 51 Pages: 101998-101998
- DOI
  10.1016/j.suronc.2023.101998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08202
[Presentation] 肝細胞癌血管内皮細胞の細胞外小胞を介した腫瘍微小環境における相互作用の解析2024
- Author(s)
  柳垣　充，赤岡宗紀，春木孝一郎，古川賢英，谷合智彦，石崎俊太，奥井紀光，松本倫典，坂本太郎，後町武志，池上　徹
- Organizer
  第60回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-24K11920
[Presentation] 肝細胞癌切除例におけるオステオぺニア合併椎体骨折の臨床的意義2024
- Author(s)
  春木孝一郎，古川賢英，赤岡宗紀，柳垣　充，谷合智彦，恩田真二，奥井紀光，松本倫典，白井祥睦，池上　徹
- Organizer
  第124回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-24K11920
[Presentation] 肝細胞癌血管内皮細胞の細胞外小胞を介した腫瘍微小環境における相互作用の解析2024
- Author(s)
  柳垣　充、赤岡宗紀、春木孝一郎、古川賢英、谷合智彦、石崎俊太、奥井紀光、松本倫典、坂本太郎、後町武志、池上　徹
- Organizer
  第60回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-24K19377
[Presentation] 肝細胞癌におけるPARK9阻害はミトコンドリア機能不全とフェロトーシスを誘導する2024
- Author(s)
  柳垣充，赤岡宗紀，春木孝一郎，古川賢英，谷合智彦，白井祥睦，奥井紀光，松本倫典，坂本太郎，後町武志，池上　徹
- Organizer
  第22回日本消化器外科学会大会
- Data Source
  KAKENHI-PROJECT-24K11920
[Presentation] 解剖学的切除可能膵癌におけるSMV/PV接触の生物学的意義2023
- Author(s)
  白井祥睦, 丹治芳明, 羽村凌雅, 後町武志, 恒松雅, 奥井紀光, 塩崎弘憲, 阿部恭平, 松本倫典, 坂本太郎, 五十嵐陽介, 谷合智彦, 柳垣充, 赤岡宗紀, 山畑勇統, 春木孝一郎, 安田淳吾, 古川賢英, 恩田真二, 池上徹
- Organizer
  JDDW2023
- Data Source
  KAKENHI-PROJECT-23K08202

1. 白井祥睦 (10785364)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
2. 春木孝一郎 (60720894)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
3. 谷合智彦 (60961860)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
4. 池上徹 (80432938)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
5. 古川賢英 (80624973)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
6. 恩田真二 (10459620)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
7. 奥井紀光 (60648864)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 安田淳吾 (90896870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 嶋田洋太 (20560824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 羽村凌雅 (60894425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 田中晴祥 (80793504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 堀内尭 (00838774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 恒松雅 (70912757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 坂本太郎 (60366234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 宇和川匡 (70287209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 高橋数冴 (00909385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 藤田雄 (10737133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yanagaki Mitsuru 柳垣 充

Research Projects

Research Products

Co-Researchers

肝癌におけるGPR15の分子生物学的機能解明および革新的癌免疫療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝細胞癌におけるライソゾームとミトコンドリアの関連に注目した革新的治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanisms of chemotherapy resistance through epigenetic analysis of pancreatic cancer and development of innovative treatment methods

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

癌微小環境に着目した肝細胞癌の分子標的薬耐性メカニズム解明と革新的治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝細胞癌の宿主免疫回避機構の解明に基づく新たな治療戦略の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝癌微小環境における癌関連血管内皮細胞の分子生物学的機能解明と革新的治療法開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝癌血管内皮細胞由来エクソソームを介した癌進展メカニズムの解明と革新的治療法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of lysosome enzymes in pancreatic cancer specific immune evasion system

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Analysis of Preoperative Risk Factors for Early Recurrence in Patients After Hepatic Resection for Intrahepatic Cholangiocarcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Short-term Outcomes of Laparoscopic<i>Versus</i>Open Liver Resection in the Elderly: A Propensity Score-matched Analysis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proposal for Prognosis-Oriented Definition of Borderline Resectable Hepatocellular Carcinoma.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The postoperative platelet-to-lymphocyte ratio predicts the outcome of patients undergoing pancreaticoduodenectomy for pancreatic head cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Superior mesenteric vein/portal vein contact in preoperative imaging indicates biological malignancy in anatomically resectable pancreatic cancer2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肝細胞癌血管内皮細胞の細胞外小胞を介した腫瘍微小環境における相互作用の解析2024

Author(s)

Organizer

Yanagaki Mitsuru 柳垣充