Uwagawa Tadashi 宇和川匡

… Alternative Names

宇和川匡ウワガワタダシ

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Researcher Number	70287209
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 東京慈恵会医科大学, 医学部, 教授 2021 – 2023: 東京慈恵会医科大学, 医学部, 准教授 1998 – 1999: 東京慈恵会医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords	Principal Investigator 膵臓癌 / リキッドバイオプシー / 獲得耐性メカニズム / オートファジー / ライソゾーム / アポトーシス / 酸性β-グルコシダーゼ / ライソゾーム酵素 / 酸性セラミダーゼ / APC遺伝子 … More / 大腸癌モデルマウス / 肝細胞成長促成因子 / loxP system / Cre / 遺伝子治療 / 切除後肝再生 Less

Elucidation of mechanisms of chemotherapy resistance through epigenetic analysis of pancreatic cancer and development of innovative treatment methodsPrincipal Investigator
- Principal Investigator
  
  宇和川匡
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
Development of innovative treatments based on pancreatic cancer-specific energy metabolism mechanisms.Principal Investigator
- Principal Investigator
  
  Uwagawa Tadashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
肝切除後の肝再生補助に関する遺伝子治療の新案-Cre/loxP systemを用いた導入遺伝子発現のコントロールは可能か?Principal Investigator
- Principal Investigator
  
  宇和川匡
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Jikei University School of Medicine

All 2024 2023 2022 2021

All Journal Article

[Journal Article] The prognosis-based classification model in resectable pancreatic cancer2024
- Author(s)
  Okui Norimitsu、Tsunematsu Masashi、Furukawa Kenei、Shirai Yoshihiiro、Haruki Koichiro、Sakamoto Taro、Uwagawa Tadashi、Onda Shinji、Gocho Takeshi、Ikegami Toru
- Journal Title
  
  Surgical Oncology
  
  Volume: 52 Pages: 102035-102035
- DOI
  10.1016/j.suronc.2024.102035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16501, KAKENHI-PROJECT-21K08806
[Journal Article] Osteosarcopenia is a significant predictor of recurrence and the prognosis after resection for extrahepatic bile duct cancer2023
- Author(s)
  Matsumoto Michinori、Onda Shinji、Igarashi Yosuke、Hamura Ryoga、Uwagawa Tadashi、Furukawa Kenei、Shirai Yoshihiro、Gocho Takeshi、Haruki Koichiro、Ikegami Toru
- Journal Title
  
  Surgery Today
  
  Volume: 54 Issue: 5 Pages: 407-418
- DOI
  10.1007/s00595-023-02747-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08806
[Journal Article] Effect of duration of adjuvant chemotherapy with S-1 (6 versus 12?months) for resected pancreatic cancer: the multicenter clinical randomized phase II postoperative adjuvant chemotherapy S-1 (PACS-1) trial2023
- Author(s)
  Kayashima Hiroto、Itoh Shinji、Shimokawa Mototsugu、Hayashi Hiromitsu、Takamori Hiroshi、Fukuzawa Kengo、Ninomiya Mizuki、Araki Kenichiro、Yamashita Yo-ichi、Sugimachi Keishi、Uchiyama Hideaki、Morine Yuji、Utsunomiya Tohru、Uwagawa Tadashi、Maeda Takashi、Baba Hideo、Yoshizumi Tomoharu
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 28 Issue: 11 Pages: 1520-1529
- DOI
  10.1007/s10147-023-02399-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08806
[Journal Article] Oesophageal elongation using magnets in adult patients.2022
- Author(s)
  Kamada T, Ohdaira H, Okada S, Takahashi J, Nakashima K, Nakaseko Y, Suzuki N, Uwagawa T, Yoshida M, Yamanouchi E, Suzuki Y.
- Journal Title
  
  Br J Surg
  
  Volume: 109 Pages: 472-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08806
[Journal Article] Phase II trial of nafamostat mesilate/gemcitabin/S-1 for unresectable pancreatic cancer.2022
- Author(s)
  Uwagawa T, Sakamoto T, Gocho T, Shiba H, Onda S, Yasuda J, Shirai Y, Hamura R, Furukawa K, Yanaga K, Ikegami T.
- Journal Title
  
  PLoS One
  
  Volume: 17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08806
[Journal Article] The impact of S-1 for the patient with lymph nodal metastasis biliary tract cancer as adjuvant chemotherapy: a multicenter database analysis.2022
- Author(s)
  Hamura R, Haruki K, Taniai T, Yanagaki M, Shirai Y, Furukawa K, Usuba T, Fujioka S, Okamoto T, Nakabayashi Y, Uwagawa T, Ikegami T.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 27 Pages: 1188-1195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08806
[Journal Article] Inhibition of lysosomal acid β-glucosidase induces cell apoptosis via impairing mitochondrial clearance in pancreatic cancer.2022
- Author(s)
  Yanagaki M, Shirai Y, Shimada Y, Hamura R, Taniai T, Horiuchi T, Takada N, Haruki K, Furukawa K, Uwagawa T, Kobayashi H, Ikegami T.
- Journal Title
  
  Carcinogenesis
  
  Volume: 43 Pages: 826-837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08806
[Journal Article] Molecular detection and clinicopathological characteristics of advanced/recurrent biliary tract carcinomas harboring the FGFR2 rearrangements: a prospective observational study (PRELUDE Study)2021
- Author(s)
  Maruki Y, Morizane C, Arai Y, Ikeda M, Ueno M, Ioka T, Naganuma A, Furukawa M, Mizuno N, Uwagawa T, Takahara N, Kanai M, Asagi A, Shimizu S, Miyamoto A, Yukisawa S, Kadokura M, Kojima Y, Furuse J, Nakajima TE, Sudo K, Kobayashi N, Hama N, Yamanaka T, Shibata T, Okusaka T.
- Journal Title
  
  J Gastroenterol
  
  Volume: 56 Pages: 250-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08806
[Journal Article] Inhibition of acid ceramidase elicits mitochondrial dysfunction and oxidative stress in pancreatic cancer cells2021
- Author(s)
  Taniai T, Shirai Y, Shimada Y, Hamura R, Yanagaki M, Takada N, Horiuchi T, Haruki K, Furukawa K, Uwagawa T, Tsuboi K, Okamoto Y, Shimada S, Tanaka S, Ohashi T, Ikegami T.
- Journal Title
  
  Cancer Sci
  
  Volume: 112 Pages: 4570-4579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08806
[Journal Article] Phase II Study of Adjuvant Chemotherapy With Gemcitabine and Nafamostat Mesilate for Pancreatic Cancer2021
- Author(s)
  Uwagawa T, Sakamoto T, Yasuda J, Shiozaki H, Furukawa K, Onda S, Gocho T, Shiba H, Yanaga K.
- Journal Title
  
  Pancreas
  
  Volume: 50 Pages: 313-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08806

1. 白井祥睦 (10785364)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 春木孝一郎 (60720894)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 池上徹 (80432938)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 古川賢英 (80624973)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. 恩田真二 (10459620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 阿部恭平 (30751292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 後町武志 (40338893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 高橋数冴 (00909385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 谷合智彦 (60961860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 柳垣充 (80979435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SAKAMOTO Taro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uwagawa Tadashi 宇和川 匡

宇和川 匡 ウワガワ タダシ

Research Projects

Research Products

Co-Researchers

Elucidation of mechanisms of chemotherapy resistance through epigenetic analysis of pancreatic cancer and development of innovative treatment methodsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of innovative treatments based on pancreatic cancer-specific energy metabolism mechanisms.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝切除後の肝再生補助に関する遺伝子治療の新案-Cre/loxP systemを用いた導入遺伝子発現のコントロールは可能か?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The prognosis-based classification model in resectable pancreatic cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteosarcopenia is a significant predictor of recurrence and the prognosis after resection for extrahepatic bile duct cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of duration of adjuvant chemotherapy with S-1 (6 versus 12?months) for resected pancreatic cancer: the multicenter clinical randomized phase II postoperative adjuvant chemotherapy S-1 (PACS-1) trial2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oesophageal elongation using magnets in adult patients.2022

Author(s)

Journal Title

Data Source

[Journal Article] Phase II trial of nafamostat mesilate/gemcitabin/S-1 for unresectable pancreatic cancer.2022

Author(s)

Journal Title

Data Source

[Journal Article] The impact of S-1 for the patient with lymph nodal metastasis biliary tract cancer as adjuvant chemotherapy: a multicenter database analysis.2022

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of lysosomal acid β-glucosidase induces cell apoptosis via impairing mitochondrial clearance in pancreatic cancer.2022

Author(s)

Journal Title

Data Source

[Journal Article] Molecular detection and clinicopathological characteristics of advanced/recurrent biliary tract carcinomas harboring the FGFR2 rearrangements: a prospective observational study (PRELUDE Study)2021

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of acid ceramidase elicits mitochondrial dysfunction and oxidative stress in pancreatic cancer cells2021

Author(s)

Journal Title

Data Source

[Journal Article] Phase II Study of Adjuvant Chemotherapy With Gemcitabine and Nafamostat Mesilate for Pancreatic Cancer2021

Author(s)

Journal Title

Data Source

Uwagawa Tadashi 宇和川匡

宇和川匡ウワガワタダシ