onodera osamu 小野寺理

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ONODERA Osamu 小野寺理

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Researcher Number	20303167
Other IDs	https://orcid.org/0000-0003-3354-5472
External Links
Affiliation (Current)	2025: 新潟大学, 脳研究所, 教授
Affiliation (based on the past Project Information) *help	2010 – 2024: 新潟大学, 脳研究所, 教授 2013: 新潟大学, 脳研究所, 准教授 2007 – 2010: Niigata University, Brain Research Ins, Associate Professor 2009: 新潟大学, 大学院・医学系研究科, 准教授 2002 – 2006: Niigata University Brain research institute, Associate professor, 脳研究所, 助教授 1999 – 2001: 新潟大学, 脳研究所, 助手
Review Section/Research Field	Principal Investigator Neurology / Biological Sciences / Medium-sized Section 52:General internal medicine and related fields / Neurology Except Principal Investigator Neurology / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology / Neurology / Human pathology / Biological Sciences … More / Basic Section 51030:Pathophysiologic neuroscience-related / Pathological medical chemistry / Nerve anatomy/Neuropathology / Radiation science Less
Keywords	Principal Investigator 神経病態 / 脳小血管 / スプライシング / 脳小血管病 / polyglutamine / 脳神経疾患 / 認知症 / ALS / TDP-43 / 筋萎縮性側索硬化症 … More / DRPLA / 脊髄小脳変性症 / 痴呆 / poly(ADP-ribose)polymerase / XRCC1 / APTX / UPS / microtubules filaments / intermediate filaments / aggresome / MTOC / unfolding protein / Huntington disease / 遺伝子 / 蛋白質 / 循環器 / RNA代謝 / HTRA1 / CARASIL / 神経変性疾患 / ポリグルタミン / 透明化 / 一細胞解析 / 一細胞オミックス / 細胞外マトリックス / 加齢 / リンパ管 / フィブロネクチン / 細胞外基質 / カンデサルタン / 血管 / 老化 / タンパク質 / 病理学 / 脳血管障害 / ゲノム / CRISPR-Cas9 / MAPT / CRISPR / Cas9 / タウオパチー / ゲノム編集 / DNA repair / CREB mediated transcription / spinocerebellar ataxia / DNA修復 / CREB依存性転写 / huntington disease / polygultamine / 蛋白 / 前頭側頭葉変性症 / 核酸 / エピゲノム / RNA / RNA結合蛋白 / 神経病帯 / 脳循環 / 脳血管 / マイクロアレイ / グリア / 神経分子病態学 / サイトカイ / 炎症 / モデルマウス / 微小循環 / TGF-β / 血管性認知症 / 周皮細胞 / 平滑筋細胞 / 血液脳関門 / 封入体 / 天然変性蛋白 / 核内小体 / 二量体 / アプラタキシン / DNA修復機構 / DNA損傷修復 / 神経病理 / 定量的PCR / 一塩基多型 / シヌクレイン / 多系統萎縮症 / ハンチントン舞踏病 / 凝集体 / GFP / CAG繰り返し配列 … More Except Principal Investigator TDP-43 / 脊髄小脳変性症 / 脳神経疾患 / ポリグルタミン病 / 筋萎縮性側索硬化症 / 神経変性疾患 / ALS / CAG repeat / 1C2 / DNA repair / spinocerebellar degeneration / ocular motor apraxia / aprataxin / cDNA / transcriptional dysregulation / polyglutamine diseases / 遺伝性神経変性疾患 / CAGリピート / 転写障害 / polyglutamine disease / 評価法 / 小脳性運動失調 / 臨床評価法 / 神経病理学 / 疾患モデル / 核内小体 / 免疫組織化学 / 多系統萎縮症 / 脳・神経 / 運動ニューロン / HITS-CLIP / RNA結合蛋白質 / Globular glial tauopathy / ４-リピートタウ / globular glial tauopathy / 皮質基底核変性症 / 進行性核上性麻痺 / 4-リピートタウ / アストロサイト / タウオパチー / 治療法開発 / 定量評価法 / 治療薬開発 / モデル線虫 / 病型分類 / 発生・分化 / オートファジー / 老化 / 癌 / 神経科学 / ストレス / G3BP2 / G3BP1 / SCF / アポトーシス / 造血幹細胞 / USP10 / ストレス顆粒 / Gene expression / Protein analysis / Animal model / Pathology / Polyglutamine disease / 遺伝子発現 / 蛋白質解析 / 動物実験 / 病理 / amino acid sequence / Two-dimensional electrophoresis / Western blotting / Spinocerebellar ataxia / ウェスタンブロッティング / 小脳変性症 / アミノ酸配列 / 2次元電気泳動 / ウエスタンブロッティング / cerebellum / liypoalbuminemia / single strand DNA break / hypoalbuminemia / hypoalbuminenia / DNA Repair / spinoxerebellar degeneration / 小脳 / 低アルブミン血症 / 眼球運動失行 / XRCC1 / アプラタキシン / 一本鎖DNA修復 / DNA修復 / hereditary neurodegenerative diseases / spinocerebellar ataxia / polygjutemine diseases / ポリグルタミシ病 / radiation hybrid panel / dentatorubral-pallidoluysian atrophy / expression profiling / CREB-dependent transcriptional activation / cAMP-responsive gene / nuclear accumulation / TAFII130 / 神経細胞死 / 転写因子 / トランスジェニックマウス / c-fos / CREB-依存性転写活性化 / animal model / transcription / molecular mechanism / neurodegeneration / 歯状核赤核・淡倉球ルイ体萎縮症 / 歯状核赤核・淡蒼球ルイ体萎縮症 / 遺伝子発現プロファイリング / CREB依存性転写活性化 / cAMP依存性遺伝病 / 核内集積 / oligomer / therapy / ataxia / SCD / 重合体形成 / 新規治療法 / 重合体 / 治療 / 神経病態 / 新経変性疾患 / 細胞内凝集体 / 神経 / 脳 / スプライシング因子 / ミニジーン / 欠損マウス / mRNA分解機構 / ナンセンス / スプライシング / TDPー４３ / 神経軸索 / プログラミング / アルゴリズム / MRS / MRI / 核磁気共鳴画像 / 遅発性脳症 / 脳機能解析 / ＤＴＩ / 拡散テンソルイメージング / ＭＲＳ / 白質脳症 / 一酸化炭素中毒 / 磁気共鳴スペクトロスコピー / シミュレーション / 数理統計学 / 神経症状 / 大脳白質 / 核磁気共鳴画像(MRI) / 初期胚発生 / Cajal小体 / SMN / U12 snRNA / GEM / 病理学 / 脳神経疾患病理学 / 治療予測マーカー / L-プラスチン / 封人体 / 人口呼吸 / 分子生物学 / 分子病理 / 封入体 / 臨床病理 / 家族性パーキンソン病 / 遺伝性脊髄小脳変性症 / 疾患感受性遺伝子 / 脊髓小脳変性症 / パーキンソン病 / 病理学的サブタイプ / 連鎖解析 / 相関解析 / 連鎖漢籍 / 脳血管障害 / 多型解析 / 分子遺伝学 / 遺伝学 / 遺伝子 / ゲノム Less

Identification of cell groups that perturb the extracellular matrix of cerebral small vessel disease and deciphering their regulatory mechanisms.Principal Investigator
- Principal Investigator
  
  小野寺理
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Niigata University
Spinal motoneuron-specific RNA regulatory programmes and their relevance to ALS pathology.
- Principal Investigator
  
  Yano Masato
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Niigata University
Approach to neurodegenerative disorders by elucidation of the excretion pathway of the brain.Principal Investigator
- Principal Investigator
  
  ONODERA OSMAU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Niigata University
Tauopathy affecting astrocytes: diversity in the tau pathology and the astrocytic molecular feature
- Principal Investigator
  
  Takahashi Hitoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
重合体形成阻害を標的としたポリグルタミン病の新規治療法開発
- Principal Investigator
  
  他田正義
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Elucidation of the significance of MAPT polymorphism associated with sporadic tauopathies by using genome editing method.Principal Investigator
- Principal Investigator
  
  Onodera Osamu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Strategies for overcoming vascular dementia focusing on dynamic functions of cerebral small vessels.Principal Investigator
- Principal Investigator
  
  Onodera Osamu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Crosstalk between stress granules and autophagy in protein degradation
- Principal Investigator
  
  Fujii Masahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Niigata University
Mechanism of protein aging from the point of turbulence of nucleic acid metabolism or its exclusion mechanism.Principal Investigator
- Principal Investigator
  
  Onodera Osamu
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Amyotrophic Lateral Sclerosis and TDP-43: Elucidation of molecular neuropathology in terms of spread from its beginning
- Principal Investigator
  
  Takahashi Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
Heterogeneity of TDP-43 pathology and clinicopathologic correlations in sporadic amyotrophic lateral sclerosis
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
U12依存性スプライシングとALSサーキットパソロジーPrincipal Investigator
- Principal Investigator
  
  小野寺理
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Autoreguation of TDP-43 in ALS
- Principal Investigator
  
  Nishizawa Masatoyo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Approach to cerebral small vessel disease: lesson from CARASIL.Principal Investigator
- Principal Investigator
  
  Onodera Osamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Developing new therapeutic drugs that inhibit oligomer formation of polyglutamine disease proteins based on the hypothesis of oligomer toxicity in polyglutamine diseases
- Principal Investigator
  
  Tada Masayoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Identification of splicing factors that bind to expanded GGGGCC repeat and TDP-43 mRNAPrincipal Investigator
- Principal Investigator
  
  Onodera Osamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Establishment of TDP-43 C-terminal deficient mice using zinc finger nuclease and application to the model for amyotrophic lateral sclerosis
- Principal Investigator
  
  SATO TOSHIYA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kitasato University
  Niigata University
ALS and TDP-43: Dose the splicing failure underlie the pathogenesis of ALS?
- Principal Investigator
  
  HITOSHI Takahashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
An immunohistochemical study on nuclear bodies in neurodegenerativediseases with abnormal protein aggregates
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Niigata University
天然変性タンパク質の機能解析によるALSの病態機序の解明Principal Investigator
- Principal Investigator
  
  小野寺理
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Molecular pathogenesis of ALS: approach from TDP-43 function.
- Principal Investigator
  
  NISHIZAWA Masatoyo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Molecular pathogenesis of cerebral small vessel disease.Principal Investigator
- Principal Investigator
  
  ONODERA Osamu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Analysis of TDP-43 functions and modeling for ALS using conditional knockout mice
- Principal Investigator
  
  SATO Toshiya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Mathematic statistical analyses of relationship between severity of neurological symptom and MRI measurements of white matter injury
- Principal Investigator
  
  TERAJIMA Kenshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Niigata University
Identification for serum biomarker for ALS associated with the function of TDP-43Principal Investigator
- Principal Investigator
  
  ONODERA Osamu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Amyotrophic lateral sclerosis and TDP-43 : elucidation of the entire neuropathological picture and molecular pathomechanism
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
L-plastin ; the possibility as a surrogate marker of polyglutamine diseases.
- Principal Investigator
  
  TOYOSHIMA Yasuko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
核内小体機能不全による非翻訳リボ核酸の異常による運動神経細胞死の研究Principal Investigator
- Principal Investigator
  
  小野寺理
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Impairment of quality control system for nucleic acids and neurodegenerative disorders.Principal Investigator
- Principal Investigator
  
  ONODERA Osamu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
The spectrum of pathological involvement in Japanese multiple system atrophy
- Principal Investigator
  
  OZAWA Tetsutaro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Elucidation of molecular mechanisms of neurological diseases based on genome analysis
- Principal Investigator
  
  TSUJI Shoji
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Atherapeutic approach to polyglutamine diseases by the activation of cellularproteolyticpathways
- Principal Investigator
  
  YAMADA Mitsunori
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Niigata University
内在性相補鎖RNAによる遺伝子発現調節機構に注目したシヌクレイン関連蛋白の解析Principal Investigator
- Principal Investigator
  
  小野寺理
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Niigata University
New polyglutamine diseases : from the neuropathologies to the identification of genes responsible for the diseases
- Principal Investigator
  
  TAKAHASHI Hitoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Niigata University
Transcriptional disturbance and Neurodegeneration.Principal Investigator
- Principal Investigator
  
  ONODERA Osamu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  NIIGATA UNIVERSITY
Identified the causative gene for EAOH end elucidation the molecular mechanisms of neurodegeneration in EAOH
- Principal Investigator
  
  TSUJI Shoji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo
Research for the role of dystrophic neurites in neuronal cell dysfunction of Polyglutamine diseasePrincipal Investigator
- Principal Investigator
  
  ONODERA Osamu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Molecular mechanisms of neurodegeneration
- Principal Investigator
  
  TSUJI Shoji
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Niigata University
Elucidation of molecular mechanisms of neurodegenerative diseases caused by expansion of CAG repeats
- Principal Investigator
  
  TSUJI Shoji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  NIIGATA UNIVERSITY
ポリグルタミン病における凝集体と神経細胞死の関連の解明と凝集体阻害剤の探求Principal Investigator
- Principal Investigator
  
  小野寺理
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurology
- Research Institution
  Niigata University

[Book] Pathologies of calcium channels; Chapter 28, IP3 Receptors in Neurodegenerative Disorders: Spinocerebellar Ataxias and Huntington’s and Alzheimer’s Diseases2014
- Author(s)
  Tada M, Nishizawa M, and Onodera O
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25461272
[Book] Annual Review神経2011巻CARASILの臨床・病理像と病態機序2011
- Author(s)
  野崎洋明,西澤正豊,小野寺理
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22390174
[Book] CARASIL GeneReviews^<TM>2010
- Author(s)
  Onodera O, Nozaki H, Fukutake T
- Publisher
  In : Pagon RA, Bird TD, Dolan CR, Stephens K, Adam MP, Seattle (WA) : University of Washington, Seattle(Internet)
- Data Source
  KAKENHI-PROJECT-22390174
[Book] University of Washington, Seattle; CARASIL. GeneReviews2010
- Author(s)
  Onodera O, Nozaki H, Fukutake T.In : Pagon RA, Bird TD, Dolan CR, Stephens K, Adam MP
- Publisher
  Seattle (WA)(Internet)
- Data Source
  KAKENHI-PROJECT-22390174
[Book] 末梢神経疾患眼球運動失行と低アルブミン血症を伴う早期発症型脊髄小脳失調症佐藤達哉(新潟大学学脳研究所神経内科)(Annual Review神経)2009
- Author(s)
  他田正義, 小野寺理
- Data Source
  KAKENHI-PROJECT-19390236
[Journal Article] High frequency of HTRA1 AND ABCC6 mutations in Japanese patients with adult-onset cerebral small vessel disease.2023
- Author(s)
  Uemura M, Hatano Y, Nozaki H, Ando S, Kondo H, Hanazono A, Iwanaga A, Murota H, Osakada Y, Osaki M, Kanazawa M, Kanai M, Shibata Y, Saika R, Miyatake T, Aizawa H, Ikeuchi T, Tomimoto H, Mizuta I, Mizuno T, Ishihara T, Onodera O.
- Journal Title
  
  J Neurol Neurosurg Psychiatry.
  
  Volume: 94(1) Pages: 74-81
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00466
[Journal Article] DNA damage stress-induced translocation of mutant FUS proteins into cytosolic granules and screening for translocation inhibitors2022
- Author(s)
  Nogami Masahiro、Sano Osamu、Adachi-Tominari Keiko、Hayakawa-Yano Yoshika、Furukawa Takako、Iwata Hidehisa、Ogi Kazuhiro、Okano Hideyuki、Yano Masato
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 15 Pages: 01-14
- DOI
  10.3389/fnmol.2022.953365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06879, KAKENHI-PUBLICLY-22H05589, KAKENHI-PROJECT-20H00485, KAKENHI-PROJECT-19H03543
[Journal Article] Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson’s disease.2021
- Author(s)
  Matsui, H.*, Ito, J., Matsui, N., Uechi, T., Onodera, O., Kakita, A.
- Journal Title
  
  Nat. Commun.
  
  Volume: - Issue: 1 Pages: 3101-3101
- DOI
  10.1038/s41467-021-23452-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02716, KAKENHI-PROJECT-20K20468, KAKENHI-PROJECT-19H01043, KAKENHI-PROJECT-19H01061, KAKENHI-PROJECT-19K08869
[Journal Article] Candesartan prevents arteriopathy progression in cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy model2021
- Author(s)
  Kato T, Manabe RI, Igarashi H, Kametani F, Hirokawa S, Sekine Y, Fujita N, Saito S, Kawashima Y, Hatano Y, Ando S, Nozaki H, Sugai A, Uemura M, Fukunaga M, Sato T, Koyama A, Saito R, Sugie A, Toyoshima Y, Kawata H, Murayama S, Matsumoto M, Kakita A, Hasegawa M, Ihara M, Kanazawa M, Nishizawa M, Tsuji S, Onodera O.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 131 Issue: 22
- DOI
  10.1172/jci140555
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-19H01043, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-20K07880
[Journal Article] Parkinson's disease and parkinsonism: Clinicopathological discrepancies on diagnosis in three patients2021
- Author(s)
  Toyoshima Yasuko、Takahashi Hitoshi、Katada Shinnichi、Kojima Naoyuki、Tada Mari、Tani Takashi、Koike Ryoko、Nozawa Takanori、Aida Izumi、Nakajima Takashi、Onodera Osamu、Kakita Akiyoshi
- Journal Title
  
  Neuropathology
  
  Volume: 41 Issue: 6 Pages: 450-456
- DOI
  10.1111/neup.12777
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07972, KAKENHI-PROJECT-20K20468, KAKENHI-PROJECT-19H01043
[Journal Article] HTRA1-Related Cerebral Small Vessel Disease: A Review of the Literature2020
- Author(s)
  Uemura Masahiro、Nozaki Hiroaki、Kato Taisuke、Koyama Akihide、Sakai Naoko、Ando Shoichiro、Kanazawa Masato、Hishikawa Nozomi、Nishimoto Yoshinori、Polavarapu Kiran、Nalini Atchayaram、Hanazono Akira、Kuzume Daisuke、Shindo Akihiro、El-Ghanem M、Abe A、Sato A、Yoshida M、Ikeuchi T、Mizuta I、Mizuno T、Onodera O
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 11 Pages: 545-545
- DOI
  10.3389/fneur.2020.00545
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07493, KAKENHI-PROJECT-19H01043
[Journal Article] Morphological characterization of glial and neuronal tau pathology in globular glial tauopathy (Types II and III)2020
- Author(s)
  Tanaka H, Toyoshima Y, Kawakatsu S, Kobayashi R, Yokota O, Terada S, Kuroda S, Miura T, Higuchi Y, Otsu H, Sanpei K, Otani K, Ikeuchi T, Onodera O, Kakita A, Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: 46 Pages: 344-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03554
[Journal Article] TDP-43 transports ribosomal protein mRNA to regulate axonal local translation in neuronal axons2020
- Author(s)
  Nagano Seiichi、Jinno Junki、Abdelhamid Rehab F.、Jin Yinshi、Shibata Megumi、Watanabe Shohei、Hirokawa Sachiko、Nishizawa Masatoyo、Sakimura Kenji、Onodera Osamu、Okada Hironori、Okada Takashi、Saito Yuko、Takahashi-Fujigasaki Junko、Murayama Shigeo、Wakatsuki Shuji、Mochizuki Hideki、Araki Toshiyuki
- Journal Title
  
  Acta Neuropathologica
  
  Volume: 140 Issue: 5 Pages: 695-713
- DOI
  10.1007/s00401-020-02205-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19H01043
[Journal Article] Amyotrophic lateral sclerosis with pallidonigroluysian degeneration: a clinicopathological study2020
- Author(s)
  Ito J, Shimizu H, Ohta K, Idezuka J, Tanaka H, Kondo H, Nakajima T, Takahashi H, Akazawa K, Onodera O, Kakita A
- Journal Title
  
  Ann Neurol
  
  Volume: 87 Issue: 2 Pages: 302-312
- DOI
  10.1002/ana.25652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03554
[Journal Article] Molecular mechanism of amyotrophic lateral sclerosis (ALS) from the viewpoint of the formation and degeneration of transactive response DNA-binding protein 43 kDa (TDP-43) inclusions2020
- Author(s)
  Kasahara Sou、Ishihara Tomohiko、Koike Yuka、Sugai Akihiro、Onodera Osamu
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 60 Issue: 2 Pages: 109-116
- DOI
  10.5692/clinicalneurol.cn-001362
- NAID
  130007802650
- ISSN
  0009-918X, 1882-0654
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09751, KAKENHI-PROJECT-19H01043
[Journal Article] Shrinkage of the myenteric neurons of the small intestine in patients with multiple system atrophy2019
- Author(s)
  Ozawa Tetsutaro、Shimizu Hiroshi、Matsui Hideaki、Onodera Osamu、Kakita Akiyoshi
- Journal Title
  
  Autonomic Neuroscience
  
  Volume: 221 Pages: 102583-102583
- DOI
  10.1016/j.autneu.2019.102583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02716, KAKENHI-PROJECT-19H01043
[Journal Article] HTRA1 Mutations Identified in Symptomatic Carriers Have the Property of Interfering the Trimer-Dependent Activation Cascade2019
- Author(s)
  Uemura Masahiro、Nozaki Hiroaki、Koyama Akihide、Sakai Naoko、Ando Shoichiro、Kanazawa Masato、Kato Taisuke、Onodera Osamu
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 10 Pages: 693-693
- DOI
  10.3389/fneur.2019.00693
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07493, KAKENHI-PROJECT-19H01043
[Journal Article] Globular glial tauopathy Type II: Clinicopathological study of two autopsy cases2019
- Author(s)
  Tanaka Hidetomo、Kawakatsu Shinobu、Toyoshima Yasuko、Miura Takeshi、Mezaki Naomi、Mano Atsushi、Sanpei Kazuhiro、Kobayashi Ryota、Hayashi Hiroshi、Otani Koichi、Ikeuchi Takeshi、Onodera Osamu、Kakita Akiyoshi、Takahashi Hitoshi
- Journal Title
  
  Neuropathology
  
  Volume: 39 Issue: 2 Pages: 111-119
- DOI
  10.1111/neup.12532
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-17H03554, KAKENHI-PROJECT-16K09228, KAKENHI-PROJECT-19K08009, KAKENHI-PROJECT-19H01043
[Journal Article] Ectopic expression induces abnormal somatodendritic distribution of tau in the mouse brain.2019
- Author(s)
  Kubo A, Ueda S, Yamane A, Wada-Kakuda S, Narita M, Matsuyama M, Nomori A, ..... Murayama S, Ihara Y, Misonou H, Miyasaka T
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 39 Issue: 34 Pages: 6781-6797
- DOI
  10.1523/jneurosci.2845-18.2019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H01043
[Journal Article] Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation2019
- Author(s)
  Sugai Akihiro、Kato Taisuke、Koyama Akihide、Koike Yuka、Konno Takuya、Ishihara Tomohiko、Onodera Osamu
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 130 Pages: 104534-104534
- DOI
  10.1016/j.nbd.2019.104534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09750, KAKENHI-PROJECT-17K09751, KAKENHI-PROJECT-19H01043
[Journal Article] Retinal Vasculopathy With Cerebral Leukodystrophy: Clinicopathologic Features of an Autopsied Patient With a Heterozygous TREX 1 Mutation2018
- Author(s)
  Saito Rie、Nozaki Hiroaki、Kato Taisuke、Toyoshima Yasuko、Tanaka Hajime、Tsubata Yutaka、Morioka Tetsuo、Horikawa Yoh、Oyanagi Kiyomitsu、Morita Takashi、Onodera Osamu、Kakita Akiyoshi
- Journal Title
  
  Journal of Neuropathology & Experimental Neurology
  
  Volume: 78 Issue: 2 Pages: 181-186
- DOI
  10.1093/jnen/nly115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-19K21314, KAKENHI-PROJECT-19K07820
[Journal Article] Frequency and characteristics of the TBK1 gene variants in Japanese patients with sporadic amyotrophic lateral sclerosis2018
- Author(s)
  Tohnai Genki、Nakamura Ryoichi、Sone Jun、Nakatochi Masahiro、Yokoi Daichi、Katsuno Masahisa、Watanabe Hazuki、Watanabe Hirohisa、Ito Mizuki、Li Yuanzhe、Izumi Yuishin、et al. Atsuta Naoki、Sobue Gen
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 64 Pages: 158.e15-158.e19
- DOI
  10.1016/j.neurobiolaging.2017.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09778, KAKENHI-PROJECT-17K16116, KAKENHI-PROJECT-17K16118, KAKENHI-ORGANIZER-26117001, KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-17J03762
[Journal Article] Robustness and Vulnerability of the Autoregulatory System That Maintains Nuclear TDP-43 Levels: A Trade-off Hypothesis for ALS Pathology Based on in Silico Data2018
- Author(s)
  Sugai Akihiro、Kato Taisuke、Koyama Akihide、Koike Yuka、Kasahara Sou、Konno Takuya、Ishihara Tomohiko、Onodera Osamu
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 12 Pages: 0-0
- DOI
  10.3389/fnins.2018.00028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09750, KAKENHI-PROJECT-17K09751, KAKENHI-PLANNED-26117006
[Journal Article] Histopathologic features of an autopsied patient with cerebral small vessel disease and a heterozygous HTRA1 mutation2018
- Author(s)
  Ito Junko、Nozaki Hiroaki、Toyoshima Yasuko、Abe Takashi、Sato Aki、Hashidate Hideki、Igarashi Shuichi、Onodera Osamu、Takahashi Hitoshi、Kakita Akiyoshi
- Journal Title
  
  Neuropathology
  
  Volume: 38 Issue: 4 Pages: 428-432
- DOI
  10.1111/neup.12473
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-16H02656, KAKENHI-PROJECT-17K09775
[Journal Article] Clinicopathologic Features of Two Patients With Sporadic Amyotrophic Lateral Sclerosis Who Maintained Communication Ability for Over 30 Years2018
- Author(s)
  Ito Junko、Shimada Tetsuro、Tada Mari、Shimizu Hiroshi、Wakabayashi Masatoshi、Yokoseki Akio、Onodera Osamu、Takahashi Hitoshi、Kakita Akiyoshi
- Journal Title
  
  Journal of Neuropathology & Experimental Neurology
  
  Volume: 77 Issue: 11 Pages: 981-986
- DOI
  10.1093/jnen/nly082
- Data Source
  KAKENHI-PLANNED-26117006
[Journal Article] CARASIL families from India with 3 novel null mutations in theHTRA1gene2017
- Author(s)
  Preethish-Kumar Veeramani、Nozaki Hiroaki、Tiwari Sarbesh、Vengalil Seena、Bhat Maya、Prasad Chandrajit、Onodera Osamu、Uemura Masahiro、Doniparthi Seshagiri、Saini Jitender、Nashi Saraswati、Polavarapu Kiran、Nalini Atchayaram
- Journal Title
  
  Neurology
  
  Volume: 89 Issue: 23 Pages: 2392-2394
- DOI
  10.1212/wnl.0000000000004710
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-16H02656
[Journal Article] A CARASIL Patient from Americas with Novel Mutation and Atypical Features: Case Presentation and Literature Review2017
- Author(s)
  Ibrahimi Muhammad、Nozaki Hiroaki、Lee Angelica、Onodera Osamu、Reichwein Raymond、Wicklund Matthew、El-Ghanem Mohammad
- Journal Title
  
  Cerebrovascular Diseases
  
  Volume: 44 Issue: 3-4 Pages: 135-140
- DOI
  10.1159/000477358
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-16H02656
[Journal Article] 特集近年注目されている白質脳症 CARASIL-(Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy)2017
- Author(s)
  上村昌寛、野崎洋明、小野寺理
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 69 Pages: 25-33
- Data Source
  KAKENHI-PROJECT-16H02656
[Journal Article] 【遺伝性脊髄小脳失調症の病態と治療展望】本邦における遺伝性脊髄小脳変性症の全体像.2017
- Author(s)
  他田正義, 横関明男, 小野寺理.
- Journal Title
  
  Brain Nerve
  
  Volume: 69 Pages: 879-890
- Data Source
  KAKENHI-PROJECT-16K09670
[Journal Article] Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL)2017
- Author(s)
  Uemura M, Nozaki H, Onodera O.
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 69 Issue: 1 Pages: 25-33
- DOI
  10.11477/mf.1416200631
- ISSN
  1344-8129, 1881-6096
- Year and Date
  2017-01-01
- Data Source
  KAKENHI-PROJECT-16H02656
[Journal Article] Familial amyotrophic lateral sclerosis with an I104F mutation in the SOD1 gene: multisystem degeneration with neurofilamentous aggregates and SOD1 inclusions.2017
- Author(s)
  Jiang H, Shimizu H, Shiga A, Tanaka M, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Neuropathology
  
  Volume: 37 Issue: 1 Pages: 69-77
- DOI
  10.1111/neup.12324
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-17H03554
[Journal Article] 【脊髄小脳変性症(SCD)-最新診療マニュアル】治療と介護の現状　パーキンソニズム.2017
- Author(s)
  他田正義, 小野寺理.
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 35 Pages: 1097-1100
- Data Source
  KAKENHI-PROJECT-16K09670
[Journal Article] Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43.2016
- Author(s)
  Koyama A, Sugai A, Kato T, Ishihara T, Shiga A, Toyoshima Y, Koyama M, Konno T, Hirokawa S, Yokoseki A, Nishizawa M, Kakita A, Takahashi H, Onodera O.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 44 Issue: 12 Pages: 5820-5836
- DOI
  10.1093/nar/gkw499
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-15H06225, KAKENHI-PROJECT-15K19479, KAKENHI-PLANNED-26117006
[Journal Article] Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes.2016
- Author(s)
  Takeuchi R, Tada M, Shiga A, Toyoshima Y, Konno T, Sato T, Nozaki H, Kato T, Horie M, Shimizu H, Takebayashi H, Onodera O, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Acta Neuropathol Commun
  
  Volume: 4 Issue: 1 Pages: 61-61
- DOI
  10.1186/s40478-016-0335-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PLANNED-26117006
[Journal Article] Pathological and Clinical Spectrum of Progressive Supranuclear Palsy: With Special Reference to Astrocytic Tau Pathology.2016
- Author(s)
  Yokoyama Y, Toyoshima Y, Shiga A, Tada M, Kitamura H, Hasegawa K, Onodera O, Ikeuchi T, Someya T, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Brain Pathol.
  
  Volume: 26 Issue: 2 Pages: 155-166
- DOI
  10.1111/bpa.12265
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-25430048, KAKENHI-PROJECT-26640029, KAKENHI-PROJECT-15K09860
[Journal Article] Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL2016
- Author(s)
  Nozaki H, Kato T, Nihonmatsu M, Saito Y, Mizuta I, Noda T, Koike R, Miyazaki K, Kaito M, Ito S, Makino M, Koyama A, Shiga A, Uemura M, Sekine Y, Murakami A, Moritani S, Hara K, Yokoseki A, Kuwano R, Endo N, Momotsu T, Yoshida M, Nishizawa M, Mizuno T, Onodera O.
- Journal Title
  
  Neurology
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293200
[Journal Article] Clinicopathological characteristics of patients with amyotrophic lateral sclerosis resulting in a totally locked-in state (communication Stage V).2016
- Author(s)
  Hayashi K, Mochizuki Y, Takeuchi R, Shimizu T, Nagao M, Watabe K, Arai N, Oyanagi K, Onodera O, Hayashi M, Takahashi H, Kakita A, Isozaki E.
- Journal Title
  
  Acta Neuropathol Commun
  
  Volume: 4 Issue: 1 Pages: 107-107
- DOI
  10.1186/s40478-016-0379-3
- NAID
  120007113458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26250017, KAKENHI-PROJECT-15K06763, KAKENHI-PROJECT-16H05583, KAKENHI-PLANNED-26117006
[Journal Article] 小脳症状をどう捉えるか：小脳機能に基づく小脳症状の再構築2016
- Author(s)
  他田正義, 西澤正豊, 小野寺理
- Journal Title
  
  MDSJ Letters
  
  Volume: 9(1) Pages: 4-5
- Data Source
  KAKENHI-PROJECT-25461272
[Journal Article] Roles of inositol 1,4,5-trisphosphate receptors in spinocerebellar ataxias.2016
- Author(s)
  Tada M, Nishizawa M, Onodera O.
- Journal Title
  
  Neurochem Int.
  
  Volume: 94 Pages: 1-8
- DOI
  10.1016/j.neuint.2016.01.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-25461272, KAKENHI-PROJECT-16K09670
[Journal Article] 小脳症状をどう捉えるか　小脳機能に基づく小脳症状の再構築2016
- Author(s)
  他田正義, 西澤正豊, 小野寺理.
- Journal Title
  
  MDSJ Letters
  
  Volume: 9 Pages: 4-5
- Data Source
  KAKENHI-PROJECT-16K09670
[Journal Article] Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL.2016
- Author(s)
  Nozaki H, Kato T, Nihonmatsu M, Saito Y, Mizuta I, Noda T, Koike R, Miyazaki K, Kaito M, Ito S, Makino M, Koyama A, Shiga A, Uemura M, Sekine Y, Murakami A, Moritani S, Hara K, Yokoseki A, Kuwano R, Endo N, Momotsu T, Yoshida M, Nishizawa M, Mizuno T, Onodera O
- Journal Title
  
  Neurology
  
  Volume: 86 Issue: 21 Pages: 1-10
- DOI
  10.1212/wnl.0000000000002694
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461276, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-16H02656
[Journal Article] Emerging molecular mechanism for cerebral small vessel disease: Lessons from hereditary small vessel disease2015
- Author(s)
  Onodera, O., Sekine, Y., Kato, T., Koyama, A., Nozaki, H. and Nishizawa, M
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Issue: 1 Pages: 7-13
- DOI
  10.1111/ncn3.134
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293200
[Journal Article] Characteristic features and progression of abnormalities on MRI for CARASIL2015
- Author(s)
  Hiroaki Nozaki, Yumi Sekine, Toshio Fukutake, Yoshinori Nishimoto, Yutaka Shimoe, Akiko Shirata, Sohei Yanagawa, Mikio Hirayama, Masato Tamura, Masatoyo Nishizawa, and Osamu Onodera
- Journal Title
  
  Neurology
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293200
[Journal Article] Characteristic features and progression of abnormalities on MRI for CARASIL.2015
- Author(s)
  Nozaki H, Sekine Y, Fukutake T, Nishimoto Y, Shimoe Y, Shirata A, Yanagawa S, Hirayama M, Tamura M, Nishizawa M, Onodera O.
- Journal Title
  
  Neurology.
  
  Volume: 85 Issue: 5 Pages: 459-463
- DOI
  10.1212/wnl.0000000000001803
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-25293200
[Journal Article] Redefining cerebellar ataxia in degenerative ataxias: lessons from recent research on cerebellar systems.2015
- Author(s)
  Tada M, Nishizawa M, Onodera O
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: - Issue: 8 Pages: 922-928
- DOI
  10.1136/jnnp-2013-307225
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461272, KAKENHI-PLANNED-26117006
[Journal Article] Haploinsufficiency of CSF-1R and clinicopathological characterization in patients with HDLS.2014
- Author(s)
  Konno T, Tada M, Tada M, Koyama A, Nozaki H, Harigaya Y, Nishimiya J, Matsunaga A, Yoshikura N, Ishihara K, Arakawa M, Isami A, Okazaki K, Yokoo H, Ihoh K, Yoneda M, Kawamura M, Inuzuka T, Takahashi H, Nishizawa M, Onodera O, Kakita A, Ikeuchi T
- Journal Title
  
  Neurology
  
  Volume: 82 Issue: 2 Pages: 139-148
- DOI
  10.1212/wnl.0000000000000046
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PUBLICLY-24111517, KAKENHI-PROJECT-25293200, KAKENHI-PROJECT-25430048
[Journal Article] Minor splicing pathway is not minor any more: implications for the pathogenesis of motor neuron diseases.2014
- Author(s)
  Onodera O, Ishihara T, Shiga A, Ariizumi Y, Yokoseki A, Nishizawa M.
- Journal Title
  
  Neuropathology
  
  Volume: 34 Issue: 1 Pages: 99-107
- DOI
  10.1111/neup.12070
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065
[Journal Article] Bunina bodies in motor and non-motor neurons revisited: A pathological study of an ALS patient after long-term survival on a respirator.2014
- Author(s)
  Kimura T, Jiang H, Konno T, Seto M, Iwanaga K, Tsujihata M, Satoh A, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Neuropathology
  
  Volume: なし Issue: 4 Pages: 392-397
- DOI
  10.1111/neup.12105
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25670417, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-26250017
[Journal Article] A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories.2014
- Author(s)
  Akimoto C, Volk AE, van Blitterswijk M, Van den Broeck M, Leblond CS, Lumbroso S, Camu W, Neitzel B, Onodera O, et al.
- Journal Title
  
  J Med Genet.
  
  Volume: 51 Pages: 419-424
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117006
[Journal Article] Features of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy.2014
- Author(s)
  Nozaki H, Nishizawa M, Onodera O.
- Journal Title
  
  Stroke.
  
  Volume: 45 Issue: 11 Pages: 3447-3453
- DOI
  10.1161/strokeaha.114.004236
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293200
[Journal Article] A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories.2014
- Author(s)
  AkimotoC, Onodera O ら
- Journal Title
  
  J Med Genet.
  
  Volume: 51 Issue: 6 Pages: 419-424
- DOI
  10.1136/jmedgenet-2014-102360
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25670417
[Journal Article] A mutation of COX6A1 causes a recessive axonal or mixed form of Charcot-Marie-Tooth disease.2014
- Author(s)
  Tamiya G, Makino S, Hayashi M, Abe A, Numakura C, Ueki M, Tanaka A, Ito C, Toshimori K, Ogawa N, Terashima T, Maegawa H, Yanagisawa D, Tooyama I, Tada M, Onodera O, Hayasaka K.
- Journal Title
  
  Am J Hum Genet
  
  Volume: 95(3) Pages: 294-300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461272
[Journal Article] C9ORF72 repeat-associated non-ATG-translated polypeptides are distributed independently of TDP-43 in a Japanese patient with c9ALS2014
- Author(s)
  Konno T　ほか
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: 40 Issue: 6 Pages: 783-788
- DOI
  10.1111/nan.12157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PROJECT-25430048, KAKENHI-PROJECT-25670417, KAKENHI-PLANNED-26117005, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-26250017
[Journal Article] [Aberration of the spliceosome in amyotrophic lateral sclerosis].2014
- Author(s)
  Ishihara T, Kakita A, Takahashi H, Onodera O, Nishizawa M.
- Journal Title
  
  Rinsho Shinkeigaku.
  
  Volume: 54 Pages: 1155-1157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253065
[Journal Article] Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis2013
- Author(s)
  Ishihara T, Ariizumi Y, Shiga A, Kato T, Tan CF, Sato T, Miki Y, Yokoo M, Fujino T, Koyama A, Yokoseki A, Nishizawa M, Kakita A, Takahashi H, Onodera O
- Journal Title
  
  Hum Mol Genet
  
  Volume: 22 Pages: 4136-4147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Sporadic ALS with compound heterozygous mutation in the SQSTM1 gene.2013
- Author(s)
  Shimizu H, Toyoshima Y, Shiga A, Yokoseki A, Arakawa K, Sekine Y, Shimohata T, Ikeuchi T, Nishizawa M, Kakita A, Onodera O, Takahashi H
- Journal Title
  
  Acta Neuropathol
  
  Volume: 126 Issue: 3 Pages: 453-459
- DOI
  10.1007/s00401-013-1150-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23590390, KAKENHI-PROJECT-24790875, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25830038
[Journal Article] [Hereditary cerebral small-vessel disease].2013
- Author(s)
  Nozaki H, Nishizawa M, Onodera O.
- Journal Title
  
  Nihon Rinsho.
  
  Volume: 71 Pages: 545-554
- NAID
  40017342931
- Data Source
  KAKENHI-PROJECT-25293200
[Journal Article] What is the key player in TDP-43 pathology in ALS: Disappearance from the nucleus or inclusion formation in the cytoplasm?2013
- Author(s)
  Onodera O
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Pages: 11-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Japanese amyotrophic lateral sclersois patients with GGGGCC hexanucleotide repeat expansion in C90RF722013
- Author(s)
  Konno T, Shiga A, Tsujino A, Sugai A, Kato T, Kanai K, Yokoseki A, Eguchi H, Kuwabara S, Nishizawa M, Takahashi H, Onodera O
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 84 Pages: 398-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.2013
- Author(s)
  Ishihara T, Ariizumi Y, Shiga A, et al ;
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 22 Issue: 20 Pages: 4136-4147
- DOI
  10.1093/hmg/ddt262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07914, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-24790875, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065
[Journal Article] Progressive myoclonus epilepsy: extraneuronal brown pigment deposition and system neurodegeneration in the brains of Japanese patients with novel SCARB2 mutations2013
- Author(s)
  Fu YJ, Aida I, Tada M, Tada M, Toyoshima Y, Takeda S, Nakajima T, Naito H, Nishizawa M, Onodera O, Kakita A, and Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: doi:10.1111/nan.12057. Pages: 12057-12057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461272
[Journal Article] Japanese amyotrophiclateral sclerosis patients withGGGGCC hexanucleotide repeatexpansion in C9ORF722013
- Author(s)
  Konno T, Shiga A, Tsujino A, Sugai A,Kato T, Kanai K, Yokoseki A, Eguchi H,Kuwabara S, Nishizawa M, Takahashi H,Onodera O
- Journal Title
  
  J NeurolNeurosurg Psychiatry
  
  Volume: 84(4) Pages: 398-401
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] 【小脳の神経学】治療研究に向けた小脳機能評価法の将来2013
- Author(s)
  徳永純, 他田正義, 永井貴大, 西澤正豊, 小野寺理
- Journal Title
  
  神経内科
  
  Volume: 78 Pages: 687-694
- Data Source
  KAKENHI-PROJECT-25461272
[Journal Article] ERBB4 Mutations that Disrupt the Neuregulin-ErbB4 Pathway Cause Amyotrophic Lateral Sclerosis Type 19.2013
- Author(s)
  Takahashi Y, Fukuda Y, Yoshimura J, Toyoda A, (33名省略）, Morishita S, Goto J and Tsuji S.
- Journal Title
  
  Am J Hum Genet
  
  Volume: 93 Issue: 5 Pages: 900-905
- DOI
  10.1016/j.ajhg.2013.09.008
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22129001, KAKENHI-PLANNED-22129002, KAKENHI-PLANNED-22129003, KAKENHI-PLANNED-22129008, KAKENHI-PUBLICLY-25110714, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25461277, KAKENHI-PROJECT-25860700, KAKENHI-PROJECT-221S0002
[Journal Article] Sporadic ALS with compound heterozygous mutation in the SQSTM1 gene2013
- Author(s)
  Shimizu H, Toyoshima Y, Shiga A, Yokoseki A, Arakawa K, Sekine Y, Shimohata T, Ikeuchi T, Nishizawa M, Kakita A, Onodera O, Takahashi H
- Journal Title
  
  Acta Neuropathol
  
  Volume: 126 Pages: 453-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Japanese amyotrophic lateral sclerosis patients with GGGGCC hexanucleotide repeat expansion in C9ORF72.2013
- Author(s)
  Konno T
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 84(4) Issue: 4 Pages: 398-401
- DOI
  10.1136/jnnp-2012-302272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23591269, KAKENHI-PROJECT-24790875, KAKENHI-PROJECT-25253065, KAKENHI-PROJECT-25670417
[Journal Article] Co-occurrence of argyrophilic grain disease in sporadic amyotrophic lateral sclerosis2012
- Author(s)
  Soma K, Fu YJ, Wakabayashi K, Onodera O, Kakita A, Takahashi H
- Journal Title
  
  Neuropathology
  
  Volume: 38(1) Issue: 1 Pages: 54-60
- DOI
  10.1111/j.1365-2990.2011.01175.x
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113506, KAKENHI-PROJECT-23659184
[Journal Article] Alterarion of POLDIP3 splicing associated with loss of function of TDP-43 in tissues affected with ALS2012
- Author(s)
  Shiga A, Ishihara T, Miyashita A, Kuwabara M, Kato T, Watanabe N, Yamahira A, Kondo C, Yokoseki A, Takahashi M, Kuwano R, Kakita A, Nishizawa M, Takahashi H, Onodera O
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Primary lateral sclerosis : upper-motor-predominant amyotrophic lateral sclerosis with frontotemporal lobar degeneration - immunohistochemical and biochemical analyses of TDP-432012
- Author(s)
  Kosaka T, Fu YJ, Shiga A, Ishidaira H, Tan CF, Tani T, Koike R, Onodera O, Nishizawa M, Kakita A, Takahashi H
- Journal Title
  
  Neuropathology
  
  Volume: 32 Pages: 373-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Co-occurrence of argyrophilic grain disease in sporadic amyotrophic lateral sclerosis2012
- Author(s)
  Soma K, Fu YJ, Wakabayashi K, Onodera O, Kakita A, Takahashi H
- Journal Title
  
  Neuropathology
  
  Volume: 38 Pages: 54-60
- Data Source
  KAKENHI-PROJECT-22659169
[Journal Article] Co-occurrence of argyrophilic grain disease in sporadic amyotrophic lateral sclerosis2012
- Author(s)
  Soma K, Fu YJ, Wakabayashi K, Onodera O, Kakita A, Takahashi H
- Journal Title
  
  Neuropathol Appl Neurobiol
  
  Volume: 38 Pages: 54-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240049
[Journal Article] Co-occurrence of argyrophilic graindisease in sporadic amyotrophiclateral sclerosis2012
- Author(s)
  Soma K, Fu YJ, Wakabayashi K, OnoderaO, Kakita A, Takahashi H
- Journal Title
  
  Neuropathol ApplNeurobiol
  
  Volume: 38(1) Pages: 54-60
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Alteration of P0LDIP3 Splicing Associated with Loss of Function of TDP-43 in Tissues Affected with ALS2012
- Author(s)
  Shiga A, et al ;
- Journal Title
  
  PLoS ONE
  
  Volume: 7(8) Issue: 8 Pages: e43120-e43120
- DOI
  10.1371/journal.pone.0043120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07914, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23890060, KAKENHI-PROJECT-24510275, KAKENHI-PROJECT-24790875, KAKENHI-PLANNED-22129004
[Journal Article] Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β12011
- Author(s)
  Shiga A, Nozaki H, Yokoseki A, Nihonmatsu M, Kawata H, Kato T, Koyama A, Arima. K, Ikeda M, Katada S, Toyoshima Y, Takahashi H, Tanaka A, Nakano I, Ikeuchi T, Nishizawa M, Onodera O
- Journal Title
  
  Hum Mol Genet
  
  Volume: 20(9) Pages: 1800-10
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] 認知症学下-その解明と治療の最新知見-臨床編血管性認知症とその類縁疾患CADASIL(皮質下梗塞および白質脳症を伴う常染色体優性脳動脈症)とCARASIL(皮質下梗塞と白質脳症を伴う脳常染色体劣性動脈症)2011
- Author(s)
  加藤泰介,西澤正豊,小野寺理
- Journal Title
  
  日本臨床増刊認知症学(下)
  
  Pages: 320-324
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] Primary lateral sclerosis : Upper-motor-predominant amyotrophic lateral sclerosis with frontotemporal lobar degeneration-immunohistochemical and biochemical analyses of TDP-432011
- Author(s)
  Kosaka T, Fu YJ, Shiga A, Ishidaira H, Tan CF, Tani T, Koike R, Onodera O, Nishizawa M, Kakita A, Takahashi H
- Journal Title
  
  Neuropathology. 2011
  
  Volume: 32 Issue: 4 Pages: 373-384
- DOI
  10.1111/j.1440-1789.2011.01271.x
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113506, KAKENHI-PROJECT-22249036, KAKENHI-PROJECT-22659169, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23659184
[Journal Article] 家族性ALS ALS10(遺伝性ALS-TDP)の臨床と病理2011
- Author(s)
  今野卓哉, 石原智彦, 西澤正豊, 小野寺理
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 29巻 Pages: 1019-1021
- Data Source
  KAKENHI-PROJECT-22659169
[Journal Article] 家族性ALS ALS10(遺伝性ALS-TDP)の臨床と病理2011
- Author(s)
  今野卓哉, 石原智彦, 西洋正豊, 小野寺理
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 29巻9号 Pages: 1019-1021
- Data Source
  KAKENHI-PUBLICLY-22113506
[Journal Article] 【血管性認知症のニューホライズン】遺伝性脳小血管病の病態機序から脳小血管病を探る2011
- Author(s)
  小野寺理
- Journal Title
  
  Dementia Japan
  
  Volume: 25 Pages: 24-31
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] 家族性ALS ALS10(遺伝性ALS-TDP)の臨床と病理2011
- Author(s)
  今野卓哉, 石原智彦, 西津正豊, 小野寺理
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 29巻9号 Pages: 1019-1021
- Data Source
  KAKENHI-PROJECT-22659169
[Journal Article] 【認知症:診断と治療の進歩】トピックス新規の認知症関連遺伝子の発見TGF-βファミリーシグナルの異常と遺伝性脳小血管病CARASILの分子病態の解析から2011
- Author(s)
  野崎洋明,西澤正豊,小野寺理
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 100巻8号 Pages: 2207-2213
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] 【血管性認知症のニューホライズン】遺伝性脳小血管病の病態機序から脳小血管病を探る2011
- Author(s)
  小野寺理
- Journal Title
  
  Dementia Japan
  
  Volume: 25巻1号 Pages: 24-31
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] 脳小血管病とは何か2011
- Author(s)
  小野寺理
- Journal Title
  
  臨床神経学
  
  Volume: 51巻6号 Pages: 399-405
- NAID
  10031164020
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] Neurological picture. Neuroaxonal integrity evaluated by MR spectroscopy in a case of CARASIL2011
- Author(s)
  Nishimoto Y, Shibata M, Onodera O, Suzuki N
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 82(8) Pages: 860-1
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] 家族性ALSALS10(遺伝性ALS-TDP)の臨床と病理2011
- Author(s)
  今野卓哉, 石原智彦, 西澤正豊, 小野寺理
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 29巻9号 Pages: 1019-1021
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] A novel mutation in the HTRA1 gene causes CARASIL without alopecia2011
- Author(s)
  Nishimoto Y, Shibata M, Nihonmatsu M, Nozaki H, Shiga A, Shirata A, Yamane K, Kosakai A, Takahashi K, Nishizawa M, Onodera O, Suzuki N
- Journal Title
  
  Neurology
  
  Volume: 76(15) Pages: 1353-5
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] ALS Update ALSの病態 FUSの観点から2010
- Author(s)
  志賀篤, 西澤正豊, 小野寺理
- Journal Title
  
  医学のあゆみ
  
  Pages: 236-240
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] CARASILの分子病態機序2010
- Author(s)
  野崎洋明,志賀篤,西澤正豊,小野寺理
- Journal Title
  
  神経内科
  
  Volume: 72巻4号 Pages: 408-412
- NAID
  40017170126
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] 【神経変性疾患におけるTDP-43】家族性筋萎縮性側索硬化症とTDP-432010
- Author(s)
  石原智彦, 横関明男, 西澤正豊, 高橋均, 小野寺理
- Journal Title
  
  最新医学
  
  Volume: 65 Pages: 1648-1653
- Data Source
  KAKENHI-PROJECT-22659169
[Journal Article] ALS Update ALSの病態FUSの観点から2010
- Author(s)
  志賀篤, 西澤正豊, 小野寺理
- Journal Title
  
  医学のあゆみ
  
  Volume: 253 Pages: 236-240
- Data Source
  KAKENHI-PROJECT-22659169
[Journal Article] Involvement of Onuf's nucleus in Machado-Joseph disease : a morphometric and immunohistochemical study.2010
- Author(s)
  Shimizu H, Yamada M, Toyoshima Y, Ikeuchi T, Onodera O, Takahashi H.
- Journal Title
  
  Acta Neuropathol 120
  
  Pages: 439-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] CARASILの分子病態学2010
- Author(s)
  志賀篤, 野崎洋明, 西澤正豊, 小野寺理
- Journal Title
  
  BRAIN and NERVE:神経研究の進歩
  
  Volume: 62巻6号 Pages: 595-599
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] 臨床トピックス遺伝性脳小血管病2010
- Author(s)
  今野卓哉,小野寺理
- Journal Title
  
  医学のあゆみ
  
  Volume: 235巻6号 Pages: 745-748
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] CARASILの分子病態学BRAIN and NERVE2010
- Author(s)
  志賀篤,野崎洋明,西澤正豊,小野寺理
- Journal Title
  
  神経研究の進歩
  
  Volume: 62巻6号 Pages: 595-599
- Data Source
  KAKENHI-PROJECT-22390174
[Journal Article] FTLD/ALS as TDP-43proteinopathies2010
- Author(s)
  Ishihara T, Ariizumi Y, Shiga A,Yokoseki A, Sato T, Toyoshima Y,Kakita A,Takahashi H, Nishizawa M,Onodera O
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 50(11) Pages: 1022-4
- NAID
  130004504601
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] Sporadic four-repeat tauopathy with frontotemporal lobar degeneration, Parkinsonism, and motor neuron disease : a distinct clinicopathological and biochemical disease entity.2010
- Author(s)
  Fu Y-J, Nishihira Y, Kuroda S, Toyoshima Y, Ishihara T, Shinozaki M, Miyashita A, Piao Y-S, Tan C-F, Tani T, Koike R, Iwanaga K, Tsujihata M, Onodera O, Kuwano R, Nishizawa M, Kakita A, Ikeuchi T, Takahashi H.
- Journal Title
  
  Acta Neuropathol 120
  
  Pages: 21-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] 【神経変性疾患におけるTDP-43】家族性筋萎縮性側索硬化症とTDP-432010
- Author(s)
  石原智彦, 横関明男, 西澤正豊, 高橋均, 小野寺理
- Journal Title
  
  最新医学
  
  Volume: 65 Pages: 1648-1653
- Data Source
  KAKENHI-PUBLICLY-22113506
[Journal Article] Clinical and pathological spectrumof TDP-43 associated ALS2010
- Author(s)
  Onodera O, Yokoseki A, Tan CF,Ishihara T, Nishiira Y, Toyoshima Y,Kakita A, Nishizawa M, Takahashi H
- Journal Title
  
  RinshoShinkeigaku
  
  Volume: 50(11) Pages: 940-2
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] 【神経変性疾患におけるTDP・43】家族性筋萎縮性側索硬化症とTDP-432010
- Author(s)
  石原智彦, 横関明男, 西澤正豊, 高橋均, 小野寺理
- Journal Title
  
  最新医学
  
  Volume: 65 Pages: 1648-1653
- Data Source
  KAKENHI-PROJECT-22249036
[Journal Article] 【ALS Update】ALSの病態FUSの観点から2010
- Author(s)
  志賀篤, 西澤正豊, 小野寺理
- Journal Title
  
  医学のあゆみ
  
  Volume: 253 Pages: 236-240
- Data Source
  KAKENHI-PUBLICLY-22113506
[Journal Article] Molecular mechanism for spinocerebellar ataxia2009
- Author(s)
  Onodera O
- Journal Title
  
  Rinsho SHinkeigaku 1
  
  Pages: 1-8
- NAID
  10024898887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390236
[Journal Article] 【癌治療・発癌・老化の鍵を握るDNA修復経路】DNA一本鎖切断損傷修復の破綻による神経変性疾患2009
- Author(s)
  他田正義, 辻省次, 西澤正豊, 小野寺理
- Journal Title
  
  細胞工学 29巻1号
  
  Pages: 60-6
- Data Source
  KAKENHI-PROJECT-19390236
[Journal Article] Familial Ischemic Cerebral Small-Vessel Disease, Alopecia, and Spondylosis Caused by Mutations in the HTRA1 Gene2009
- Author(s)
  Hara K, Shiga A, Fukutake T, Nozaki H, Miyashita A, Yokoseki A, Kawata H, Koyama A, Arima K, Takahashi T, Ikeda M, Shiota H, Tamura M, Shimoe Y, Hirayama M, Arisato T, Yanagawa S, Tanaka A, Nakano I, Ikeda S, Yoshida Y, Yamamoto T, Ikeuchi T, Kuwano R, Nishizawa M, Tsuji S, Onodera O.
- Journal Title
  
  New Engl J Med 360
  
  Pages: 1729-1739
- Data Source
  KAKENHI-PROJECT-17019006
[Journal Article] Molecular mechanism for spinocerebellar ataxias2009
- Author(s)
  Onodera O. Rinsho Shinkeigaku
- Journal Title
  
  Japanese 49(1)
  
  Pages: 1-8
- NAID
  10024898887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390236
[Journal Article] 前頭側頭葉変性症(FTLD)とALSにおけるTDP-43をめぐる最近の進歩Bunina小体を認める家族性ALSに認めたTDP-43ミスセンス変異2009
- Author(s)
  小野寺理ら
- Journal Title
  
  Dementia Japan 22
  
  Pages: 91-91
- Data Source
  KAKENHI-PROJECT-20659139
[Journal Article] Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology.2009
- Author(s)
  Nishihira Y, Tan C-F, Hoshi Y, Iwanaga K, Yamada M, Kawachi I, Tsujihata M, Hozumi I, Morita T, Onodera O, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Acta Neuropathol 117
  
  Pages: 45-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Selective occurrence of TDP-43-immunoreactive inclusions in the lower motor neurons in Machado-Joseph disease.2009
- Author(s)
  Tan C-F, Yamada M, Toyoshima Y, Yokseki A, Miki Y, Hoshi Y, Kaneko H, Ikeuchi T, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Acta Neuropathol 118
  
  Pages: 553-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] 【脊髄小脳変性症What's new?】劣性遺伝性家族性眼球運動失行と低アルブミン血症を伴う早期発症型脊髄小脳失調症(EAOH/AOA1)2009
- Author(s)
  佐藤達哉, 他田正義, 小野寺理
- Journal Title
  
  Clinical Neuroscience 27巻1号
  
  Pages: 82-8
- Data Source
  KAKENHI-PROJECT-19390236
[Journal Article] Spinocerebellar Ataxia Type 17 (SCA17).2008
- Author(s)
  Toyoshima Y, Onodera O, Yamada M, et al.
- Journal Title
  
  GeneReviews at GeneTests
- URL
  http://www.genetests.org
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500322
[Journal Article] Sporadic amyotrophic lateral sclerosis : two pathological patterns shown by analysis of distribution of TDP-43-immunreactive neuronal and glial cytoplasmic inclusions.2008
- Author(s)
  Nishihira Y, Tan C-F, Onodera O, Toyoshima Y, Yamada M, Morita T, Nishizawa M, Kakita A, Takahashi H.
- Journal Title
  
  Acta Neuropathol 116
  
  Pages: 169-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic2008
- Author(s)
  Takahashi T, Kikuchi S, Katada S, Nagai Y, Nishizawa M, Onodera O.
- Journal Title
  
  Hum Mol Genet 17
  
  Pages: 345-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500322
[Journal Article] TDP-43 mutation in familial amyotrophic lateral sclerosis.2008
- Author(s)
  Yokoseki A, Shiga A, Tan C-F, Tagawa A, Kaneko H, Koyama A, Eguchi H, Tsujino A, Ikeuchi T, Kakita A, Okamoto K, Nishizawa M, Takahashi H, Onodera O.
- Journal Title
  
  Ann Neurol 63
  
  Pages: 538-542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Bunina小体のみられる家族性ALSに認めたTDP-43ミスセンス変異2008
- Author(s)
  小野寺理
- Journal Title
  
  Dementia Japan 22
  
  Pages: 245-251
- Data Source
  KAKENHI-PROJECT-20240037
[Journal Article] Multiplex families with multiple system atrophy.2007
- Author(s)
  Hara K, Momose Y, Tokiguchi S, Shimohata M, Terajima K, Onodera O, Kakita A, Yamada M, Takahashi H, Hirasawa M, Mizuno Y, Ogata K, Goto J, Kanazawa I, Nishizawa M, Tsuji S
- Journal Title
  
  Arch Neurol. 64(4)
  
  Pages: 545-551
- Data Source
  KAKENHI-PROJECT-17019006
[Journal Article] Total deletion and a missense mutation of ITPR1 in Japanese SCA15 families.2007
- Author(s)
  Hara, K, Shiga, A, Nozaki, H,…Tsuji, S,…and Onodera, O.
- Journal Title
  
  Ann Neurol 64
  
  Pages: 544-544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019006
[Journal Article] Aprataxin, causative gene product, for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends.2007
- Author(s)
  Takahashi, T., Tada, M.,…Tsuji, S., Nishizawa, M., Onodera, O.
- Journal Title
  
  Nucleic Acids Res 35
  
  Pages: 3797-3809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019006
[Journal Article] 【脳神経疾患の分子病態と治療への展開アルツハイマー病、パーキンソン病、発達障害、精神疾患などの発症メカニズムを分子から解く】神経難病の病態トピックスDNA修復の異常と劣性遺伝性失調症2007
- Author(s)
  他田正義, 横関明男, 小野寺理
- Journal Title
  
  実験医学 25巻13号
  
  Pages: 1988-1994
- Data Source
  KAKENHI-PROJECT-19390236
[Journal Article] Aprataxin, causative gene product for EAOH/AOAI, repairs DNA single-strand breaks with 3'-phosphate and 3'-phosphoglycolate ends2007
- Author(s)
  Takahashi T, Tada M, Igarashi S, Koyama A, Date H, Yokoseki A, Shiga A, Yoshida Y, Tsuji S, Nishizawa M, Onodera O
- Journal Title
  
  Nucleic Acids Res (in press)
- Data Source
  KAKENHI-PROJECT-17019006
[Journal Article] Novel locus for benign hereditary chorea with adult-onset maps to chromosome 8q21.3-q23.32007
- Author(s)
  Shimohata T, Hara K, Sanpei K, Nunomura J, Maeda T, Kawachi I, Kanazawa M, Kasuga K, Miyashita A, Kuwano R, Hirota K, Tsuji S, Onodera O, Nishizawa M, Honma Y
- Journal Title
  
  Brain (In press)
- Data Source
  KAKENHI-PROJECT-17019006
[Journal Article] Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends2007
- Author(s)
  Takahashi T, Tada M, Igarashi S, Koyama A, Date H, Yokoseki A, Shiga A, Yoshida Y, Tsuji S, Nishizawa M, Onodera O
- Journal Title
  
  Nucleic Acids Res 35(11)
  
  Pages: 3797-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390236
[Journal Article] Polyglutamine represses cAMP-responsive-element-mediated transcription without aggregate formation.2005
- Author(s)
  Takahashi T, Nozaki K, Tsuji S, Nishizawa M, Onodera O.
- Journal Title
  
  Neuroreport. 16(3)
  
  Pages: 295-299
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Polyglutamine represses cAMP-responsive-element-mediated transcription without aggregate formation.2005
- Author(s)
  Takahashi T, Nozaki K, Tsuji S, S, Nishizawa M, Onodera O.
- Journal Title
  
  Neuroreport 16(3)
  
  Pages: 295-299
- Data Source
  KAKENHI-PROJECT-17019006
[Journal Article] Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.2004
- Author(s)
  Sano Y, Date H, Igarashi S, Onodera O, Oyake M, Takahashi T, Hayashi S, Morimatsu M, Takahashi H, Makifuchi T, Fukuhara N, Tsuji S.
- Journal Title
  
  Ann Neurol. 55(2)
  
  Pages: 241-249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Five year follow up of a patient with spinal and bulbar muscular atrophy treated with leuprorelin.2004
- Author(s)
  Shimohata T, Kimura T, Nishizawa M, Onodera O, Tsuji S
- Journal Title
  
  J Neurol Neurosurg Psychiatry 75
  
  Pages: 206-207
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210008
[Journal Article] 感覚神経細胞とPurkinje細胞に共通する神経変性の原因はあるのか-常染色体劣性遺伝性脊髄小脳変性症の解明から学ぶこと2004
- Author(s)
  小野寺理
- Journal Title
  
  神経研究の進歩 48巻5号
  
  Pages: 751-760
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] The FHA domain of aprataxin interacts with the C-terminal region of XRCC1.2004
- Author(s)
  Date H, Igarashi S, Sano Y, Takahashi T, Takahashi T, Takano H, Tsuji S, Nishizawa M, Onodera O.
- Journal Title
  
  Biochem Biophys Res Commun. 325(4)
  
  Pages: 1279-1285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Beta-synuclein gene alterations in dementia with Lewy bodies.2004
- Author(s)
  Ohtake H, Limprasert P, Fan Y, Onodera O, Kakita A, Takahashi H, Bonner LT, Tsuang DW, Murray IV, Lee VM, Trojanowski JQ, Ishikawa A, Idezuka J, Murata M, Toda T, Bird TD, Leverenz JB, Tsuji S, La Spada AR.
- Journal Title
  
  Neurology. 63(5)
  
  Pages: 805-811
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Five year follow up of a patient with spinal and bulbar muscular atrophy treated with leuprorelin.2004
- Author(s)
  Shimohata T, Kimura T, Nishizawa M, Onodera O, Tsuji S.
- Journal Title
  
  J Neurol Neurosurg Psychiatry 75
  
  Pages: 206-207
- Data Source
  KAKENHI-PROJECT-12210008
[Journal Article] Five year follow up of a patient with spinal and bulbar muscularatrophy treated with leuprorelin.2004
- Author(s)
  Shimohata T, Kimura T, Nishizawa M, Onodera 0, Tsuji S.
- Journal Title
  
  J Neurol Neurosurg Psychiatry 75
  
  Pages: 206-207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210008
[Journal Article] 常染色体劣性遺伝性脊髄小脳変性症2004
- Author(s)
  小野寺理
- Journal Title
  
  神経内科 60巻5号
  
  Pages: 497-505
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Five year follow up of a patient with spinal and bulbar muscular atrophy treated with leuprorelin.2004
- Author(s)
  Shimohata T, Kimura T, Nishizawa M, Onodera O, Tsuji S.
- Journal Title
  
  J Neural Neurosurg Psychiatry. 75(8)
  
  Pages: 1206-1207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Aprataxin, a novel protein that protects against genotoxic stress.2004
- Author(s)
  Gueven N, Becherel OJ, Kijas AW, Chen P, Howe O, Rudolph JH, Gatti R, Date H, Onodera O, Taucher-Scholz G, Lavin MF.
- Journal Title
  
  Hum Mol Genet. Epub 2004 Mar 25 13(10)
  
  Pages: 1081-1093
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] The FHA domain of aprataxin (APTX) interacts with the C terminal region of XRCC1.2004
- Author(s)
  Date, H, Igarashi, S, Sano, Y, Takahashi, T, Takahashi, T, Takano, H, Tsuji, S, Nishizawa, S, Onodera, O.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 325
  
  Pages: 1279-1285
- Data Source
  KAKENHI-PROJECT-12210008
[Journal Article] The FHA domain of aprataxin (APTX) interacts with the C terminal region of XRCC1.2004
- Author(s)
  Date, H, Igarashi, S, Sano, Y, Takahashi, T, Takahashi, T, Takano, H, Tsuji, S, Nishizawa, S, Onodera, O
- Journal Title
  
  Biochem. Biophys. Res. Commun. 325
  
  Pages: 1279-1285
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210008
[Journal Article] Sacsin-related autosomal recessive ataxia without prominent retinal myelinated fibers in Japan.2004
- Author(s)
  Hara K, Onodera O, Endo M, Kondo H, Shiota H, Miki K, Tanimoto N, Kimura T, Nishizawa M.
- Journal Title
  
  Mov Disord. 20(3)
  
  Pages: 380-382
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] SCA17 homozygote showing Huntington's disease-like phenotype.2004
- Author(s)
  Toyoshima Y, Yamada M, Onodera O, Shimohata M, Inenaga C, Fujita N, Morita M, Tsuji S, Takahashi H.
- Journal Title
  
  Ann Neurol. 55(2)
  
  Pages: 281-286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] The FHA domain of aprataxin (APTX) interacts with The C terminal region of XRCC1.2004
- Author(s)
  Date, H, Igarashi, S, Sano, Y, Takahashi, T, Takahashi, T, Takano, H, Tsuji, S, Nishizawa, S, Onodera, 0.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 325
  
  Pages: 1279-1285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210008
[Journal Article] Aprataxin, the causative protein for early-onset ataxia with ocular motor apraxia and hypoalbuminemia, is a nuclear protein wi2004
- Author(s)
  Sano, Y., Date, H, Igarashi, S, Onodera, O, Oyake, M, Takahashi, T, Hayashi, S, Morimatsu, M, Takahashi, H, Makifuchi, T, Fukuhara, N, Tsuji, S.
- Journal Title
  
  Ann.Neurol. 55
  
  Pages: 241-249
- Data Source
  KAKENHI-PROJECT-12210008
[Journal Article] Quantitative evaluation of brainstem involvement in multiple system atrophy by diffusion-weighted MR imaging.2004
- Author(s)
  Kanazawa M, Shimohata T, Terajima K, Onodera O, Tanaka K, Tsuji S, Okamoto K, Nishizawa M.
- Journal Title
  
  J Neural. 251(9)
  
  Pages: 1121-1124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Aprataxin, the causative protein for early-onset ataxia with ocular motor apraxia and hypoalbuminemia, is a nuclear protein with a potential role as a nucleotide repair protein.2004
- Author(s)
  Sano, Y., Date, H, Igarashi, S, Onodera, O, Oyake, M, Takahashi, T, Hayashi, S, Morimatsu, M, Takahashi, H, Makifuchi, T, Fukuhara, N, Tsuji, S
- Journal Title
  
  Ann. Neurol. 55
  
  Pages: 241-249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210008
[Journal Article] Aprataxin, the causative protein for early-onset ataxia with ocular motor apraxia and hypoalbuminemia, is a nuclear protein with a potential role as a nucleotide repair protein.2004
- Author(s)
  Sano, Y., Date, H, Igarashi, S, Onodera, 0, Oyake, M, Takahashi, T, Hayashi, S, Morimatsu, M, Takahashi, H, Makifuchi, T, Fukuhara, N, Tsuji, S.
- Journal Title
  
  Ann. Neurol 55
  
  Pages: 241-249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210008
[Journal Article] Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity.2004
- Author(s)
  Popiel HA, Nagai Y, Onodera O, Inui T, Fujikake N, Urade Y, Strittmatter WJ, Burke JR, Ichikawa A, Toda T.
- Journal Title
  
  Biochem Biophys Res Commun. 317(4)
  
  Pages: 1200-1206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Severe generalized dystonia as a presentation of a patient with aprataxin gene mutation.2003
- Author(s)
  Sekijima Y, Hashimoto T, Onodera O, Date H, Okano T, Naito K, Tsuji S, Ikeda S.
- Journal Title
  
  Mov Disord. 18(10)
  
  Pages: 1198-1200
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390272
[Journal Article] Familial Ischemic Cerebral Small-Vessel Disease, Alopecia, and Spondylosis Caused by Mutations in the HTRAI Gene
- Author(s)
  Hara K, Shiga A, Fukutake T, suji S, Onodera O
- Journal Title
  
  New Engl J Med (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019006
[Journal Article] Co-occurrence of argyrophilic grain disease in sporadic amyotrophic lateral sclerosis.
- Author(s)
  Soma K, Fu J-Y, Wakabayashi K, Onodera O, Kakita A, Takahashi H.
- Journal Title
  
  Neuropathol Appl Neurobiol in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240037
[Patent] 小脳血管病の予防又は治療用医薬組成物2020
- Inventor(s)
  小野寺理　加藤泰介
- Industrial Property Rights Holder
  小野寺理　加藤泰介
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H01043
[Patent] Association of HTRA1 mutations and familial ischemic cerebral small-vessel dieases2010
- Inventor(s)
  辻省次, 小野寺理
- Industrial Property Rights Holder
  The University of Tokyo
- Filing Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-17019006
[Presentation] DNA damage stress-induced translocation of mutant FUS proteins into cytosolic granules and screening for translocation inhibitors2023
- Author(s)
  Masahiro Nogami, Osamu Sano, Keiko Adachi-Tominari, Yoshika Hayakawa-Yano, Takako Furukawa, Hidehisa Iwata, Kazuhiro Ogi, Hideyuki Okano and Masato Yano
- Organizer
  CSHL-Asia ~The Now and Future of RNA therapeutics~
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03543
[Presentation] Deficiency of Quaking results in the dysregulation of RNA metabolism and motor neuron degeneration2022
- Author(s)
  Yoshika Hayakawa-Yano, Takako Furukawa, Kenji Sakimura, Hirohide Takebayashi, Osamu Onodera, Hideyuki Okano, Masato Yano
- Organizer
  日本神経科学学会-Neuro2022
- Data Source
  KAKENHI-PROJECT-19H03543
[Presentation] Deficiency of Quaking results in the dysregulation of RNA metabolism and motor neuron degeneration2022
- Author(s)
  Masato Yano, Hideyuki Okano, Hirohide Takebayashi, Osamu Onodera, Kenji Sakimura, Takako Furukawa and Yoshika Hayakawa-Yano
- Organizer
  日本RNA学会
- Data Source
  KAKENHI-PROJECT-19H03543
[Presentation] 遺伝子解析が解き明かす脳小血管病病態2022
- Author(s)
  小野寺理
- Organizer
  日本人類遺伝学会第67回大会シンポジウム4全ゲノム配列解析時代の神経・筋疾患
- Invited
- Data Source
  KAKENHI-PROJECT-22H00466
[Presentation] An RNA-binding protein Quaking safeguards motor neuron function through pre-mRNA processing2021
- Author(s)
  Yoshika Hayakawa-Yano, Takako Furukawa, Akihide Koyama Chihiro Nakamoto, Kenji Sakimura, Osamu Onodeara, Hirohide Takebayashi, Hideyuki Okano and Masato Yano
- Organizer
  日本神経化学会
- Data Source
  KAKENHI-PROJECT-19H03543
[Presentation] Familial SVD, CARASIL and Treatments2020
- Author(s)
  Osamu Onodera
- Organizer
  VasCog 2020: Virtual International Conference of The VasCog Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01043
[Presentation] 遺伝性脳小血管病の鑑別診断と分子病態2020
- Author(s)
  小野寺理
- Organizer
  第３９回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01043
[Presentation] HTRA1活性低下による脳小血管病2019
- Author(s)
  小野寺理
- Organizer
  Stroke 2019
- Invited
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] Gene therapy for DRPLA model mice by AAV-delivered CRISPR / Cas92019
- Author(s)
  加藤泰介　小野寺理ら
- Organizer
  Keystone symposia (Genome Engineering: From Mechanisms to Therapies (B4))
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Diversity and its treatment strategy of cerebral small vessel disease. lesson from the hereditary cerebral small vessel disease2019
- Author(s)
  Osamu Onodera
- Organizer
  The 9th Japan-Korea Joint Stroke Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01043
[Presentation] 核内非膜性オルガネラと運動神経変性疾患2019
- Author(s)
  小野寺理
- Organizer
  第38回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01043
[Presentation] 脳小血管異常の分子病態と脳白質病変との関係2019
- Author(s)
  小野寺理
- Organizer
  第28回日本脳ドック学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01043
[Presentation] Morphological features of neuronal and glial tau pathology in GGT (Types II and III)2019
- Author(s)
  Tanaka H, Toyoshima Y, Kawakatsu S, Miura T, Ikeuchi T, Onodera O, Takahashi H, Kakita A
- Organizer
  19th International Congress of Neuropathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03554
[Presentation] TARDBP pre-mRNA with a mutation causes disturbance of TDP-43 autoregulation via altered interaction with ALS-related splicing factors2018
- Author(s)
  須貝章弘　小野寺理ら
- Organizer
  29th International Symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The SMN2 gene copy number states can affect the onset risk and survival time in Japanese ALS.2018
- Author(s)
  石原智彦　小野寺理ら
- Organizer
  PACTALS soul 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Development of Neurofilament-L high sensitivity assay by proximity-dependent DNA ligation method2018
- Author(s)
  笠原壮　小野寺理ら
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Does the DNA methylation state of the TARDBP 3'-UTR cause sporadic ALS?2018
- Author(s)
  小池　佑佳　小野寺理ら
- Organizer
  第41回　日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 片頭痛を認める遺伝性脳小血管病の臨床的検討2018
- Author(s)
  酒井直子　小野寺理ら
- Organizer
  第46回頭痛学会総会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 遺伝性脳小血管病における微小出血の特徴2018
- Author(s)
  上村昌寛, 野崎洋明, 酒井直子先生, 小野寺理
- Organizer
  第43回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] TARDBP mutations and ALS-related splicing factors that cause disturbances in TDP-43 autoregulation2018
- Author(s)
  須貝章弘　小野寺理ら
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The decrease of copy number of SMN2 gene in progressive muscular atrophy.2018
- Author(s)
  石原智彦　小野寺理ら
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The frequency of mutations in NOTCH3 or HTRA1 gene among _Japanese CSVD patients2018
- Author(s)
  野崎洋明　小野寺理ら
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Phenotypic suppression of DRPLA model mice using CRISPR / Cas9 system.2018
- Author(s)
  加藤泰介　小野寺理ら
- Organizer
  Keystone symposia (Advances in Neurodegenerative Disease Research and Therapy (Z3))
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Efficacy evaluation of nusinersen in an adult spinal muscular atrophy case using peripheral blood mRNA2018
- Author(s)
  石原智彦　小野寺理ら
- Organizer
  29th international symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 遺伝性脳小血管病における微小出血の特徴2018
- Author(s)
  上村昌寛, 野崎洋明, 酒井直子先生, 小野寺理
- Organizer
  第43回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] The DNA methylation status of TARDBP 3’-UTR affects its alternative splicing.2018
- Author(s)
  小池　佑佳　小野寺理ら
- Organizer
  Advances in Neurodegenerative Disease Research and Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The alternative splicing of TARDBP mRNA is affected by the DNA methylation status of TARDBP gene.2018
- Author(s)
  小池　佑佳　小野寺理ら
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 成人発症脳症血管病を呈する一卵性双生児に認めたCOL4A1スプライスサイト多型の検討2018
- Author(s)
  酒井直子　小野寺理ら
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] CARASIL症候性キャリアの一例2017
- Author(s)
  野崎洋明, 伊藤絢子, 阿部崇, 豊島靖子,佐藤晶, 橋立英樹, 五十嵐修一, 高橋均, 小野寺理, 柿田明美
- Organizer
  第36回日本認知症学会学術集会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Distinct Molecular Mechanisms of Htra1 Mutants in Manifesting Heterozygotes With Carasil.2017
- Author(s)
  Hiroaki Nozaki, Taisuke Kato, Megumi Nihonmatsu, Yohei Saito, Osamu Onodera, et al.
- Organizer
  International stroke conference 2017
- Place of Presentation
  Houston (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] Characteristic Brain Features of Manifesting　Heterozygotes With Cerebral Autosomal Recessive Arteriopathy With Subcortical Infarcts and Leukoencephalopathy.2017
- Author(s)
  Masahiro Uemura, Hiroaki Nozaki, Yumi Sekine, , Osamu Onodera et al.
- Organizer
  International stroke conference 2017
- Place of Presentation
  Houston (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] 進行性核上性麻痺：短期経過剖検例の病理組織学的検討.2017
- Author(s)
  張　路, 豊島靖子, 柿田明美, 小野寺　理, 高橋　均
- Organizer
  第58回日本神経病理学会
- Data Source
  KAKENHI-PROJECT-17H03554
[Presentation] RVCL関連変異の細胞内局在についての検討．2017
- Author(s)
  笠原杏子, 加藤泰介, 野崎洋明, 小山哲秀, 小野寺理．
- Organizer
  第36回日本認知症学会学術集会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Molecular analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Kato T, Koyama A, Onodera O
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] “CORRECT” for introducing nucleotide substitution with CRISPR/Cas9 system in MAPT gene.2017
- Author(s)
  Koike Y, Koyama A, Shiga A, Yokoseki A, Onodera O
- Organizer
  The 23rd World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03554
[Presentation] How are neurovascular units maintained in aging? From a study of HSCVD2017
- Author(s)
  小野寺理
- Organizer
  Brain Protein Aging and Dementia Control, 2nd International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] “CORRECT” for introducing nucleotide substitution with CRISPR/Cas9 system in MAPT gene.2017
- Author(s)
  Yuka Koike, Akihide Koyama, Atsushi Shiga, Akio Yokoseki, Osamu Onodera.
- Organizer
  XXⅢ World Congress of Neurology.
- Data Source
  KAKENHI-PROJECT-16K15479
[Presentation] The SMN2 gene copy number states can affect the onset risk and survival time in Japanese ALS2017
- Author(s)
  Ishihara T, Toyoda S, Koyama A, Tada , Atsuta N, Nakamura R, Tohnai G, Sone J, Izumi Y, Kaji R, Morita M, Taniguchi A, Kakita A, Sobue G, Nishizawa M, Onodera O Japanese Consortium for Amyotrophic Lateral Sclerosis Research (JaCALS)
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] セリンプロテアーゼHTRA1の機能欠損は、脳小血管病を引き起こす; Serine protease HTRA1 deficiency induces arteriopathy in cerebral small vessels2017
- Author(s)
  Kato T, Sekine Y, Fujita N, Nozaki H, Hirokawa S, Sato T, Onodera O
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] The SMN2 gene copy number states can affect the onset risk and survival time in Japanese ALS2017
- Author(s)
  Ishihara T, Toyoda S, Koyama A, Tada , Atsuta N, Nakamura R, Tohnai G, Sone J, Izumi Y, Kaji R, Morita M, Taniguchi A, Kakita A, Sobue G, Nishizawa M, Onodera O Japanese Consortium for Amyotrophic Lateral Sclerosis Research (JaCALS)
- Organizer
  28th international symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 脳小血管の機能と疾病の分子病態2017
- Author(s)
  小野寺理
- Organizer
  第8回日本脳血管・認知症学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] “CORRECT” for introducing nucleotide substitution with CRISPR/Cas9 system in MAPT2017
- Author(s)
  Yuka Koike, Akihide Koyama, Atsushi Shiga, Akio Yokoseki, Osamu Onodera.
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K15479
[Presentation] タンパク質老化に寄与する脳小血管ユニットの異常－非神経細胞の視点から－2017
- Author(s)
  小野寺理
- Organizer
  新学術領域研究［グリアアセンブリ］［脳タンパク質老化］公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] CARASIL症候性キャリアの一例2017
- Author(s)
  野崎洋明, 伊藤絢子, 阿部崇, 豊島靖子,佐藤晶, 橋立英樹, 五十嵐修一, 高橋均, 小野寺理, 柿田明美
- Organizer
  第36回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] 脳小血管の機能と疾病の分子病態2017
- Author(s)
  小野寺理
- Organizer
  第8回日本脳血管・認知症学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 家族性脳小血管病患者で報告された変異型HTRA1蛋白質の機能解析2017
- Author(s)
  上村昌寛, 野崎洋明, 加藤泰介, 小山哲秀, 小野寺理
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] セリンプロテアーゼHTRA1の機能欠損は、脳小血管病を引き起こす; Serine protease HTRA1 deficiency induces arteriopathy in cerebral small vessels2017
- Author(s)
  Kato T, Sekine Y, Fujita N, Nozaki H, Hirokawa S, Sato T, Onodera O
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] <Altered allele-specific gene expression by an ALS-causative TDP-43 mutation2017
- Author(s)
  須貝章弘、廣川祥子、小山哲秀、今野卓哉、小野寺理
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Stress granules and autophagy control degradation of neuropathogenic RNA-binding proteins2017
- Author(s)
  Masahiro Fujii, Toshifumi Hara, Masaya Higuchi, Osamu Onodera, Masahiko Takahashi
- Organizer
  日本神経科学学会
- Data Source
  KAKENHI-PROJECT-15H04704
[Presentation] The prevalence estimates of HTRA1-associated cerebral small vessel disease2017
- Author(s)
  Hiroaki Nozaki, Akihide Koyama, Masahiro Uemura, Taisuke Kato, Osamu Onodera
- Organizer
  The 8th Korea-Japan Joint Stroke Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] Protease activity analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Kato T, Koyama A, Onodera O
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] A non-genetically modified iPSC-derived neuron model with an increased expression of intrinsic TDP-432017
- Author(s)
  Akihiro Sugai, Genri Tohyama, Taisuke Kato, Tomohiko Ishihara, Osamu Onodera
- Organizer
  Amyotrophic lateral sclerosis & Related Motor Neuron Disease (Gordon Research Conference)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The prevalence estimates of HTRA1-associated cerebral small vessel disease2017
- Author(s)
  Hiroaki Nozaki, Akihide Koyama, Masahiro Uemura, Taisuke Kato, Osamu Onodera
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 脳小血管病の分子病態：CARASILからのアプローチ2017
- Author(s)
  小野寺理
- Organizer
  第36回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] The absence of hypertension and the presence of psychiatric symptoms suggest a genetic disorder among patients suspected for hereditary cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Sakai N, Onodera O
- Organizer
  The 8th Korea Joint Stroke Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Molecular analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Kato T, Koyama A, Onodera O
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] A NON-GENETICALLY MODIFIED HUMAN NEURONAL MODEL OF ALS WITH AN INCREASED EXPRESSION OF INTRINSIC TDP-432017
- Author(s)
  A. Sugai, T. Kato, T. Ishihara, O. Osamu
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Molecular analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Kato T, Koyama A, Onodera O
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] 家族性脳小血管病患者で報告された変異型HTRA1蛋白質の機能解析2017
- Author(s)
  上村昌寛, 野崎洋明, 加藤泰介, 小山哲秀, 小野寺理
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Molecular analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Kato T, Koyama A, Onodera O
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The absence of hypertension and the presence of psychiatric symptoms suggest a genetic disorder among patients suspected for hereditary cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Sakai N, Onodera O
- Organizer
  The 8th Korea Joint Stroke Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] CARASIL：HTRA1活性の低下と脳小血管病2017
- Author(s)
  小野寺理
- Organizer
  第49回日本動脈硬化学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] Distinct mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL2017
- Author(s)
  野崎洋明, 加藤泰介, 水田依久子, 水野敏樹, 西澤正豊,小野寺理
- Organizer
  第114回日本内科学会総会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] “CORRECT” for introducing nucleotide substitution with CRISPR/Cas9 system in MAPT　gene2017
- Author(s)
  Koike Y, Koyama A, Shiga A, Yokoseki A, Onodera O
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H03554
[Presentation] The prevalence estimates of HTRA1-associated cerebral small vessel disease2017
- Author(s)
  Hiroaki Nozaki, Akihide Koyama, Masahiro Uemura, Taisuke Kato, Osamu Onodera
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] CARASIL：HTRA1活性の低下と脳小血管病2017
- Author(s)
  小野寺理
- Organizer
  第49回日本動脈硬化学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The alternative splicing of TARDBP mRNA is affected by the methylation status2017
- Author(s)
  Yuka Koike, Akihiro Sugai, Akio Yokoseki, Osamu Onodera
- Organizer
  28th international symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 脳小血管病の分子病態：CARASILからのアプローチ2017
- Author(s)
  小野寺理
- Organizer
  第36回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] How are neurovascular units maintained in aging? From a study of HSCVD2017
- Author(s)
  小野寺理
- Organizer
  Brain Protein Aging and Dementia Control, 2nd International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 家族性脳小血管病患者で同定された変異型HTRA1蛋白質のプロテアーゼ活性解析2017
- Author(s)
  上村昌寛, 野崎洋明, 加藤泰介, 小山哲秀, 小野寺理
- Organizer
  第47回新潟神経学夏季セミナー
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The alternative splicing of TARDBP mRNA is affected by the ALS10 associated mutations and methylation status2017
- Author(s)
  Yuka Koike, Akihiro Sugai, Takuya Konno, Akihide Koyama, Misaki Koyama, Taisuke Kato, Tomohiko Ishihara, Akio Yokoseki, Osamu Onodera
- Organizer
  Amyotrophic lateral sclerosis & Related Motor Neuron Disease (Gordon Research Conference)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] iPatax: iPad Application Software for Evaluating Ataxia.2017
- Author(s)
  Takahiro Nagai, Masayoshi Tada, Jun Tokunaga, Osamu Onodera.
- Organizer
  World Congress of Neurology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09670
[Presentation] “CORRECT” for introducing nucleotide substitution with CRISPR/Cas9 system in MAPT　gene2017
- Author(s)
  Yuka Koike, Akihide Koyama, Atsushi Shiga, Akio Yokoseki, Osamu Onodera
- Organizer
  第40回日本神経科学大会．
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Serine protease HTRA1 deficiency induces arteriopathy in cerebral small vessels2017
- Author(s)
  Kato T, Sekine Y, Fujita N, Nozaki H, Hirokawa S, Sato T, Onodera O
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Therapeutic strategy utilizing gene editing by CRISPR/Cas9 for polyglutamine disease using DRPLA model2017
- Author(s)
  Kato T, Hirokawa S, Fujita N, Sato T, Tsuji S, Onodera O
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Distinct mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL2017
- Author(s)
  野崎洋明, 加藤泰介, 水田依久子, 水野敏樹, 西澤正豊,小野寺理
- Organizer
  第114回日本内科学会総会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] タンパク質老化に寄与する脳小血管ユニットの異常－非神経細胞の視点から－2017
- Author(s)
  小野寺理
- Organizer
  新学術領域研究［グリアアセンブリ］［脳タンパク質老化］公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] RVCL関連変異の細胞内局在についての検討．2017
- Author(s)
  笠原杏子, 加藤泰介, 野崎洋明, 小山哲秀, 小野寺理．
- Organizer
  第36回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] “CORRECT” for introducing nucleotide substitution with CRISPR/Cas9 system in MAPT gene2017
- Author(s)
  Yuka Koike, Akihide Koyama, Atsushi Shiga, Akio Yokoseki, Osamu Onodera
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 家族性脳小血管病患者で同定された変異型HTRA1蛋白質のプロテアーゼ活性解析2017
- Author(s)
  上村昌寛, 野崎洋明, 加藤泰介, 小山哲秀, 小野寺理
- Organizer
  第47回新潟神経学夏季セミナー
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] Promoting excellence in ALS registry and research. Hot topics: Molecular mechanism. ALS registry and research in Japan2017
- Author(s)
  小野寺理
- Organizer
  “PACTALS” and “Brain Protein Aging and Dementia Control” Project Joint Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Protease activity analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Kato T, Koyama A, Onodera O
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] The prevalence estimates of HTRA1-associated cerebral small vessel disease2017
- Author(s)
  Hiroaki Nozaki, Akihide Koyama, Masahiro Uemura, Taisuke Kato, Osamu Onodera
- Organizer
  The 8th Korea-Japan Joint Stroke Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The expression of Human endogenous retrovirus-K in the neuronal tissues of Japanese ALS patients.2016
- Author(s)
  Ishihara T, Koyama A, Kato T, Takeuchi R, Tada M, Kakita A, Onodera O.
- Organizer
  Key stone symposium: Common Mechanisms of Neurodegeneration
- Place of Presentation
  Keystone (Colorado), USA
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Applying "CORRECT" for introducing a mutation in the MAPT gene.2016
- Author(s)
  Yuka Koike, Akihide Koyama, Atsushi Shiga, Akio Yokoseki, Osamu Onodera
- Organizer
  4th Symposium on RNA Metabolism in Neurological Disease.
- Place of Presentation
  San Diego. （アメリカ合衆国）
- Year and Date
  2016-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15479
[Presentation] A trade-off theory for TDP-43 proteinopathya ”robust yet fragile” nature of the autoregulation.2016
- Author(s)
  Sugai A, Onodera O.
- Organizer
  The 4th Symposium on RNA Metabolism in Neurological Disease
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] 脊髄小脳変性症に対するバレニクリン酒石酸塩の治療効果の検討2016
- Author(s)
  他田正義，徳永純，徳武孝允，石原智彦，小野寺理，西澤正豊.
- Organizer
  第34回日本神経治療学会総会
- Place of Presentation
  米子コンベンションセンター（鳥取県米子市）
- Data Source
  KAKENHI-PROJECT-16K09670
[Presentation] Appearance of unique tau-positive astrocytes in the motor cortex in amyotrophic lateral sclerosis.2016
- Author(s)
  竹内亮子, 清水　宏, 他田真理, 豊島靖子, 小野寺　理, 西澤正豊, 高橋　均, 柿田明美.
- Organizer
  第57回日本神経病理学会
- Place of Presentation
  ホテルニューキャッスル（青森県・弘前市）
- Year and Date
  2016-06-01
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Analysis of intracellular distribution of TDP-43 mRNA in affected spinal motor neuron with ALS.2016
- Author(s)
  Kato T, Koyama A, Sugai A, Toyoshima Y, Kakita A, Takahashi H, Nishizawa M, Onodera O.
- Organizer
  Key stone symposium: Common Mechanisms of Neurodegeneration
- Place of Presentation
  Keystone (Colorado), USA
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Applying "CORRECT" for introducing a mutation in the MAPT gene.2016
- Author(s)
  Yuka Koike, Akihide Koyama, Atsushi Shiga, Akio Yokoseki, Osamu Onodera
- Organizer
  4th Symposium on RNA Metabolism in Neurological Disease.
- Place of Presentation
  San Diego. (USA)
- Year and Date
  2016-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 脊髄小脳変性症に対するバレニクリン酒石酸塩の治療効果の検討2016
- Author(s)
  他田正義，徳永純，徳武孝允，石原智彦，野崎洋明，関根有美，堅田慎一，横関明男，小野寺理，西澤正豊.
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09670
[Presentation] Analysis of intracellular distribution of TDP-43 mRNA in affected spinal motor neuron with ALS.2016
- Author(s)
  Taisuke Kato, Akihide Koyama, Akihiro Sugai, Yasuko Toyoshima, Akiyoshi Kakita, Hitoshi Takahashi, Masatoyo Nishizawa, Osamu Onodera.
- Organizer
  Key stone symposium. Common Mechanisms of Neurodegeneration
- Place of Presentation
  Keystone, Colorado (USA)
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] A trade-off theory for TDP-43 proteinopathy; a 'robust yet fragile' nature of the autoregulation.2016
- Author(s)
  Akihiro Sugai, Osamu Onodera
- Organizer
  4th Symposium on RNA Metabolism in Neurological Disease.
- Place of Presentation
  San Diego. (USA)
- Year and Date
  2016-11-10
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] The expression of Human endogenous retrovirus-K in the neuronal tissues of Japanese ALS patients.2016
- Author(s)
  Tomohiko Ishihara, Akihide Koyama, Taisuke Kato, Ryoko Takeuchi, Mari Tada, Akiyoshi Kakita, Osamu Onodera.
- Organizer
  Key stone symposium. Common Mechanisms of Neurodegeneration
- Place of Presentation
  Keystone, Colorado (USA)
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Dominant Negative HTRA1 Mutations in Cerebral Small Vessel Disease.2015
- Author(s)
  Nozaki H, Kato T, Nihonmatsu M, Saito Y, Mizuta I, Noda T, Koike R, Miyazaki K, Kaito M, Ito S, Makino M, Koyama A, Shiga A, Uemura M, Sekine Y, Murakami A, Moritani S, Hara K, Yokoseki A, Kuwano R, Endo N, Momotsu T, Yoshida M, Nishizawa M, Mizuno T, Onodera O.
- Organizer
  9th International Congress on Vascular Dementia; ICVD 2015
- Place of Presentation
  Ljubljana, Slovenija
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293200
[Presentation] The SMN gene copy number states in Japanese ALS patients.2015
- Author(s)
  T.Ishihara, S.Toyoda, A.Koyama, R.Nakamura, G. Tohnai, N.Atsuta, G.Sobue, M.Nishizawa, O. Onodera
- Organizer
  10th Brain Research Conference: RNA Metabolism in Neurological Disease
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670417
[Presentation] Distinct patterns of neuronal and glial TDP-43 inclusions in motor cortex.2015
- Author(s)
  Takeuchi R, Tada M, Toyohima Y, Shiga A, Sato A, Horie M, Takebayashi H, Onodera O, Nishizawa M, Takahashi H, Kakita A
- Organizer
  第56回日本神経学会
- Place of Presentation
  朱鷺メッセ（新潟県・新潟市）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] The SMN gene copy number states in Japanese ALS patients.2015
- Author(s)
  T.Ishihara, S.Toyoda, A.Koyama, R.Nakamura, G. Tohnai, N.Atsuta, G.Sobue, M.Nishizawa, O. Onodera
- Organizer
  10th Brain Research Conference: RNA Metabolism in Neurological Disease
- Place of Presentation
  Chicag (USA)
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] TDP-43陽性封入体の出現を認めた家族性ALSの姉妹剖検例.2015
- Author(s)
  清水　宏, 田中英智, 松崎紗矢香, 黒羽泰子, 金沢雅人, 小池亮子, 堀川　楊, 小柳清光, 小野寺　理, 西澤正豊, 柿田明美, 高橋　均
- Organizer
  第56回日本神経病理学会
- Place of Presentation
  九州大学医学部百年講堂（福岡県・福岡市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Characteristic brain MRI features in HTRA1 mutation heterozygotes.2015
- Author(s)
  Masahiro Uemura, Hiroaki Nozaki, Yumi Sekine, Ikuko Mizuta, Tomoko Noda, Kazuhide Miyazaki, Muichi Kaito, Yoshinori Nishimoto,　Yutaka Shimoe, Akiko Shirata, Kiyomi Yamane, Sohei Yanagawa, Mikio Hirayama, Masato Tamura, Toshiki Mizuno, Masatoyo　Nishizawa, and Osamu Onodera.
- Organizer
  9th International Congress on Vascular Dementia; ICVD 2015
- Place of Presentation
  Ljubljana, Slovenija
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293200
[Presentation] 小脳症状をどう捉えるか：小脳機能に基づく小脳症状の再構築2015
- Author(s)
  他田正義, 小野寺理, 西澤正豊
- Organizer
  第9回パーキンソン病・運動障害疾患コングレス
- Place of Presentation
  品川プリンスホテル（東京都品川区）
- Year and Date
  2015-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-25461272
[Presentation] Overexpression of intrinsic TDP-43 by disruption of the autoregulation in vivo.2015
- Author(s)
  Akihiro Sugai, Taisuke Kato, Masatoyo Nishizawa, Osamu Onodera.
- Organizer
  EMBO | EMBL Symposia Mechanisms of Neurodegeneration
- Place of Presentation
  Heidelberg (Germany)
- Year and Date
  2015-07-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670417
[Presentation] Depletion of TDP-43 induces mitochondrial fragmentation.2015
- Author(s)
  Ito G, Koyama A, Shiga A, Hirokawa S, Toyoshima Y, Kakita A, Nishizawa M, Onodera O.
- Organizer
  ALS MND 2015 26th International Symposium on ALS/MND
- Place of Presentation
  Orland (USA)
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670417
[Presentation] Kinect を用いた3次元歩行解析システムによる小脳性歩行障害の解析2015
- Author(s)
  他田正義, 徳永純, 小野寺理, 西澤正豊
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-25461272
[Presentation] Depletion of TDP-43 induces mitochondrial fragmentation.2015
- Author(s)
  Gaku Ito, Akihide Koyama, Atsushi Shiga, Sachiko Hirokawa, Yasuko Toyoshima, Akiyoshi Kakita, Masatoyo Nihizawa, Osamu Onodera.
- Organizer
  Neuroscience 2015
- Place of Presentation
  Chicago, (USA)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Detection of CRISPR/Cas9 induced-rare genome editing events by droplet-digital PCR.2015
- Author(s)
  Siga A, Onodera O.
- Organizer
  10th Brain Research Conference: RNA Metabolism in Neurological Disease
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670417
[Presentation] Depletion of TDP-43 induces mitochondrial fragmentation.2015
- Author(s)
  Ito G, Koyama A, Shiga A, Hirokawa S, Toyoshima Y, Kakita A, Nishizawa M, Onodera O.
- Organizer
  26th International Symposium on ALS/MND
- Place of Presentation
  Orland (USA)
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Detection of CRISPR/Cas9 induced-rare genome editing events by droplet-digital PCR.2015
- Author(s)
  Siga A, Onodera O.
- Organizer
  10th Brain Research Conference: RNA Metabolism in Neurological Disease
- Place of Presentation
  Chicago, (USA)
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Distinct patterns of neuronal and glial TDP-43 inclusions in motor cortex.2015
- Author(s)
  Takeuchi R, Tada M, Toyoshima Y, Shiga A, Sato T, Horie M, Takebayashi H, Onodera O, Nishizawa M, Takahashi H, Kakita A
- Organizer
  第56回日本神経学会
- Place of Presentation
  朱鷺メッセ（新潟県・新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26640029
[Presentation] he SMN gene copy number states in Japanese ALS patients.2015
- Author(s)
  T.Ishihara, S.Toyoda, A.Koyama, R.Nakamura, G. Tohnai, N.Atsuta, G.Sobue, M.Nishizawa, O. Onodera
- Organizer
  10th Brain Research Conference: RNA Metabolism in Neurological Disease
- Place of Presentation
  Chicago, (USA)
- Year and Date
  2015-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Overexpression of intrinsic TDP-43 by disruption of the autoregulation in vivo.2015
- Author(s)
  Akihiro Sugai, Taisuke Kato, Masatoyo Nishizawa, Osamu Onodera.
- Organizer
  EMBO | EMBL Symposia Mechanisms of Neurodegeneration
- Place of Presentation
  Heidelberg (Germany)
- Year and Date
  2015-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Depletion of TDP-43 induces mitochondrial fragmentation.2015
- Author(s)
  Gaku Ito, Akihide Koyama, Atsushi Shiga, Sachiko Hirokawa, Yasuko Toyoshima, Akiyoshi Kakita, Masatoyo Nihizawa, Osamu Onodera.
- Organizer
  Neuroscience 2015
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] verexpression of intrinsic TDP-43 by disruption of the autoregulation in vivo.2015
- Author(s)
  Akihiro Sugai, Taisuke Kato, Masatoyo Nishizawa, Osamu Onodera.
- Organizer
  EMBO | EMBL Symposia Mechanisms of Neurodegeneration
- Place of Presentation
  Heidelberg, (Germany)
- Year and Date
  2015-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Update in amyotrophic lateral sclerosis2014
- Author(s)
  Osamu Onodera, Masatoyo Nishizawa, Hitoshi Takahashi
- Organizer
  XVIII International congress of neuropathology.
- Place of Presentation
  Sheratom Rio Hotel, Rio de Janeiro,Brazil
- Year and Date
  2014-09-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-25110714
[Presentation] Alternation of miRNA expression in TDP-43 depleted spinal motor neuron2014
- Author(s)
  Atsushi Shiga, Chigusa Kondo, Sachiko Hirokawa, Akinori Miyashita, Toshiya Sato, Kenji Sakimura, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  Neuroscience 2014
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PUBLICLY-25110714
[Presentation] TDP-43 is autoregulated by multiple excisions of introns in exon6 and reservation of mRNA in nucleus by TDP-432014
- Author(s)
  Akihide Koyama, Akihiro Sugai, Taisuke Kato, Takuya Konno, Tomohiko Ishihara, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  Neuroscience 2014
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PUBLICLY-25110714
[Presentation] The reduction of minor spliceosome and aberrant splicing in ALS.2014
- Author(s)
  Tomohiko Ishihara,Akihide Koyama, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  Cell symposia Regulatory RNAs
- Place of Presentation
  Claremont Hotel & Spa, USA
- Year and Date
  2014-10-20
- Data Source
  KAKENHI-PUBLICLY-25110714
[Presentation] Endogenous TDP-43 over-expression model with disrupted auto-regulation2014
- Author(s)
  Akihiro Sugai, Taisuke Kato, Akihide Koyama, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  10th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  Hilton San Diego Resort & Spa, USA
- Year and Date
  2014-10-12
- Data Source
  KAKENHI-PUBLICLY-25110714
[Presentation] Analysis of intracellular distribution of TDP-43 mRNA in affected spinal motor neuron with ALS2014
- Author(s)
  Taisuke Kato, Akihide Koyama, Akihiro Sugai, Yasuko Toyoshima, Akiyoshi Kakita, Hitoshi Takahashi, Osamu Onodera
- Organizer
  Neuroscience 2014
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PUBLICLY-25110714
[Presentation] SCARB2変異を認めた進行性ミオクローヌスてんかん 2剖検例の臨床病理・生化学的解析．2014
- Author(s)
  他田正義，付永娟，会田泉，他田真理，武田茂樹，豊島靖子，中島孝，内藤明彦，高橋均，小野寺理，西澤正豊．
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-05-21
- Data Source
  KAKENHI-PROJECT-25461272
[Presentation] RNA metabolism and ALS2014
- Author(s)
  Osamu Onodera
- Organizer
  Neuroscience 2014
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-12
- Invited
- Data Source
  KAKENHI-PUBLICLY-25110714
[Presentation] 人工ヌクレアーゼ技術による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用2014
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，小野寺理，横山峯介，笹岡俊邦．
- Organizer
  第55回新潟生化学懇話会
- Place of Presentation
  長岡技術科学大学（新潟県・長岡市）
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] iPatax：小脳性運動失調の新たな定量評価法．2014
- Author(s)
  徳永純，他田正義，永井貴大，小野寺理，西澤正豊．
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-05-21
- Data Source
  KAKENHI-PROJECT-25461272
[Presentation] iPatax: A new method for quantitative assessment for motor coordination of ataxia.2014
- Author(s)
  Tada M, Tokunaga J, Nagai T, Nishizawa M, Onodera O.
- Organizer
  AAN Annual Meeting 2014
- Place of Presentation
  Philadelphia, PA
- Year and Date
  2014-05-01
- Data Source
  KAKENHI-PROJECT-25461272
[Presentation] MRI Features of Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy.2013
- Author(s)
  Hiroaki Nozaki, Yumi Sekine, Toshio Fukutake, Yoshinori Nishimoto, Mamoru Shibata, Akiko Shirata, Kiyomi Yamane, Yutaka Shimoe, Sohei Yanagawa, Mikio Hirayama, Imaharu Nakano, Norihiro Suzuki, Masatoyo Nishizawa, Osamu Onodera.
- Organizer
  The 8th International Congress on Vascular Dementia
- Place of Presentation
  アテネギリシャ
- Data Source
  KAKENHI-PROJECT-25293200
[Presentation] TDP-43量はTDP-43に惹起される自己mRNAのスプライシングで制御される2013
- Author(s)
  須貝章弘、小山哲秀、今野卓哉、加藤泰介、西澤正豊、小野寺理
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] 筋萎縮性側索硬化症の大脳皮質におけるTDP-43の組織学的および生化学的解析.2013
- Author(s)
  竹内亮子, 志賀　篤, 他田真理,今野卓也, 豊島靖子, 柿田明美, 小野寺　理, 西澤正豊, 高橋　均
- Organizer
  第54回日本神経病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] TDP-43 is autoregulated by multiple excisions of introns in exon6 and reservation of mRNA in nucleus by TDP-432013
- Author(s)
  Akihide Koyama, Akihiro Sugai, Taisuke Kato, Takuya Konno, Tomohiko Ishihara, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  24th International Symposium on ALS/MND
- Place of Presentation
  Milan　イタリア
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] An emerging molecular mechanism for the cerebral small vessel disease2013
- Author(s)
  Osamu Onodera
- Organizer
  54th Annual Meeting of the Japanese Society of Neurology
- Place of Presentation
  Tokyo
- Invited
- Data Source
  KAKENHI-PROJECT-25293200
[Presentation] Alternative splicing or polyadenylation, which is the major mechanism for auto-regulation of TDP-43?2013
- Author(s)
  Akihiro Sugai, Akihide Koyama, Taisuke Kato, Takuya Konno, Tomohiko Ishihara, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  RNA Metabolism in Neurological Disease:8th Brain Research Conference
- Place of Presentation
  SanDiego アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] 等速直線運動の速度変動に着手した小脳性運動失調の新たな定量評価法2013
- Author(s)
  徳永純，他田正義，永井貴大，小野寺理，西澤正豊
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461272
[Presentation] 筋萎縮性側索硬化症の大脳皮質におけるTDP-43 の組織学的および生化学的解析2013
- Author(s)
  竹内亮子, 志賀篤, 他田真理, 今野卓也, 豊島靖子, 柿田明美, 小野寺理, 西澤正豊, 高橋均
- Organizer
  第54回日本神経病理学会
- Place of Presentation
  東京
- Year and Date
  2013-04-25
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] Reduction of U12 snRNAs in nervous tissues with TDP-43 pathology in amyotrophic lateral sclerosis2012
- Author(s)
  Ishihara T, Shiga A, Yokoseki A, Kakita A, Nishizawa M, Takahashi H, Onodera O
- Organizer
  Society For Neuroscience 2012
- Place of Presentation
  New Orleans,USA
- Year and Date
  2012-10-17
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] Molecular pathogenesis of cerebral small vessel disease - lesson from CARASIL.2012
- Author(s)
  小野寺理
- Organizer
  Stroke 2012
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] 脳小血管病とは何か2012
- Author(s)
  小野寺理
- Organizer
  第134回日本神経学会東海北陸地方会
- Place of Presentation
  金沢
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] RNA代謝からTDP-43 proteinopathyの病態に迫る2012
- Author(s)
  小野寺理
- Organizer
  第53回神経病理学会総会学術研究会(招待講演)
- Place of Presentation
  新潟
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Molecular pathogenesis of cerebral small vessel disease-lesson from CARASIL2012
- Author(s)
  小野寺理
- Organizer
  Stroke 2012
- Place of Presentation
  Tokyo
- Year and Date
  2012-04-29
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] 筋萎縮性側索硬化症の克服を目指して2012
- Author(s)
  小野寺理
- Organizer
  新潟医学会特別例会
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] 本邦の9FTD/ALSのまとめと展望2012
- Author(s)
  小野寺理
- Organizer
  神経変性疾患に関する調査研究班　平成24年度ワークショップ
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] ALS患者神経組織ではスプライシング関連機能性RNAが低下する2012
- Author(s)
  石原智彦,志賀篤,横尾麻衣子,有泉優子,横関明男,譚春鳳,柿田明美,西澤正豊,高橋均,小野寺理
- Organizer
  第53回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 筋萎縮性側索硬化症の克服を目指して2012
- Author(s)
  小野寺理
- Organizer
  新潟医学会特別講演
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 筋萎縮性側索硬化症の克服を目指して2012
- Author(s)
  小野寺理
- Organizer
  新潟医学会特別例会(招待講演)
- Place of Presentation
  新潟
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] 本邦の9FTD/ALSのまとめと展望2012
- Author(s)
  小野寺理
- Organizer
  厚労省神経変性疾患に関する調査研究班　平成24年度ワークショップ
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 脳小血管病の分子病態機序を探る2012
- Author(s)
  小野寺理
- Organizer
  第10回首都圏脳卒中フォーラム
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] CARASILの分子病態機序2012
- Author(s)
  小野寺理
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  つくば
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] Primary lateral sclerosis : an immunohistochemical and biochemical study of pathological TDP-43 in two cases2012
- Author(s)
  Kosaka T, Fu YJ, Shiga A, Onodera O, Nishizawa M, Kakita A, Takahashi H
- Organizer
  The 8th International Conference on Frontotemporal Dementias
- Place of Presentation
  Manchester, UK
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] RNA代謝からTDP-43 proteinopathyの病態に迫る2012
- Author(s)
  小野寺理
- Organizer
  第53回　神経病理学会総会学術研究会
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] 本邦の9FTD/ALSのまとめと展望神経変性疾患に関する調査研究班2012
- Author(s)
  小野寺理
- Organizer
  平成24年度ワークショッフ(招待講演)
- Place of Presentation
  東京
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] RNA代謝からTDP-43 proteinopathyの病態に迫る2012
- Author(s)
  小野寺理
- Organizer
  第53回　神経病理学会総会学術研究会
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Alteration of snRNAs in amyotrophic lateral sclerosis2011
- Author(s)
  T.ISHIHARA, A.SHIGA, A.KAKITA, A.YOKOSEKI, M.NISHIZAWA, H.TAKAHASHI, O.ONODERA
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] Alteration of snRNAs in amyotrophic lateral sclerosis2011
- Author(s)
  T. ISHIHARA, A. SHIGA, A. KAKITA, A. YOKOSEKI, M. NISHIZAWA, H. TAKAHASHI, O. ONODERA
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins in Neurological Disease
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A. SHIGA, T. ISHIHARA, A. MIYASHITA, T. KATO, M. KUWABARA, A. YOKOSEKI, R. KUWANO, A. KAKITA, H. TAKAHASHI, M. NISHIZAWA, O. ONODERA
- Organizer
  米国神経科学会
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Alteration of snRNAs in amyotrophic lateral sclerosis2011
- Author(s)
  T.ISHIHARA, A.SHIGA, A.KAKITA, A.YOKOSEKI, M.NISHIZAWA, H.TAKAHASHI, O.ONODERA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] Tardbp欠損マウスのmRNA選択的スプライシングと組織特異的な多様性2011
- Author(s)
  廣川祥子,佐藤俊哉,石原知彦,藤野赳至,近藤千草,横山峯介,崎村健司,西澤正豊,小野寺理
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MIYASHITA, T.KATO, M.KUWABARA, A.YOKOSEKI, R.KUWANO, A.KAKITA, H.TAKAHASHI, M.NISHIZAWA, O.ONODERA
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] Alteration of snRNAs in amyotrophic lateral sclerosis2011
- Author(s)
  T.ISHIHARA, A.SHIGA, A.KAKITA, A.YOKOSEKI, M.NISHIZAWA, H.TAKAHASHI, O.ONODERA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Alteration of snRNAs in amyotrophic lateral sclerosis 20112011
- Author(s)
  T. ISHIHARA, A. SHIGA, A. KAKITA, A. YOKOSEKI, M. NISHIZAWA, H. TAKAHASHI, O. ONODERA
- Organizer
  米国神経科学会
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Tardbp欠損マウスのmRNA選択的スプライシングと組織特異的な多様性Tar dbp alternatively spliced mRNA and tissue-specific variation in heterozy gous Tardbp-deficient mice2011
- Author(s)
  廣川祥子, 佐藤俊哉, 石原知彦, 藤野赳至, 近藤千草, 横山峯介, 崎村健司, 西澤正豊, 小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MIYASHITA, T.KATO, M.KUWABARA, A.YOKOSEKI, R.KUWANO, A.KAKITA, H.TAKAHASHI, M.NISHIZAWA, O.ONODERA
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Alteration of snRNAs inamyotrophic lateral sclerosis2011
- Author(s)
  T. ISHIHARA, A. SHIGA, A. KAKITA A.YOKOSEKI, M. NISHIZAWA, H. TAKAHASHI,O. ONODERA
- Organizer
  6th Brain Research Conference RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D. C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A. SHIGA, T. ISHIHARA, A. MIYASHITA, T. KATO M. KUWABARA, A. YOKOSEKI, R. KUWANO, A. KAKITA, H. TAKAHASHI, M. NISHIZAWA, O. ONODERA
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins Neurological Disease
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MIYASHITA, T.KATO, M.KUWABARA, A.YOKOSEKI, R.KUWANO, A.KAKITA, H.TAKAHASHI, M.NISHIZAWA, O.ONODERA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MIYASHITA, T.KATO, M.KUWABARA, A.YOKOSEKI, R.KUWANO, A.KAKITA, H.TAKAHASHI, M.NISHIZAWA, O.ONODERA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A.SHIGA, T.ISHIHARA, A. MIYASHITA, T.KATO, M.KUWABARA, A.YOKOSEKI, R.KUWANO, A.KAKITA, H.TAKAHASHI, M.NISHIZAWA, O.ONODERAI
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] TGF-βファミリーシグナルの異常と脳小血管病2011
- Author(s)
  小野寺理
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] Alteration of snRNAs in amyotrqohic lateral sclerosis2011
- Author(s)
  T.ISHIHARA, A.SHIGA, A.KAKITA, A.YOKOSEKI, M.NISHIZAWA, H.TAKAHASHI, O.ONODERA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Aberrant splicing of POLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MIYASHITA, T.KATO, M.KUWABARA, A.YOKOSEKI, R.KUWANO, A.KAITA, H.TAKAHASHI, M.NISHIZAWA, O.ONODERAKA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Aberrant splicing ofPOLDIP3 gene in motor neuron with ALS.2011
- Author(s)
  A. SHIGA1, T. ISHIHARA1, A.MIYASHITA1, T. KATO1, M. KUWABARA1, A. YOKOSEKI2, R. KUWANO1, A. KAKITA1,H. TAKAHASHI1, M. NISHIZAWA1, O. ONODERA1
- Organizer
  6th Brain Research Conference RNA-Binding Proteins in NeurologicalDisease
- Place of Presentation
  Washington, D. C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] ALS関連蛋白TDP-43の自己発現調節機能に関与するスプライシング因子の検討Splicing factors involved in an autoregulation of the ALS-associated protein TDP-432011
- Author(s)
  桑原美咲, 石原智彦, 志賀篤, 今野卓哉, 小山哲秀, 西澤正豊, 小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] ALS関連蛋白TDP-43の自己発現調節機能に関与するスプライシング因子の検討Splicing factors involved in anautoregulation of the ALS-associated protein TDP-432011
- Author(s)
  桑原美咲,石原智彦,志賀篤,今野卓哉,小山哲秀,西澤正豊,小野寺理
- Organizer
  分子生物学
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] 筋萎縮性側索硬化症における嗜銀顆粒性認知症の共存について2011
- Author(s)
  相馬健一, 付永娟, 若林孝一, 小野寺理, 柿田明美, 高橋均
- Organizer
  第52回日本神経病理学会京都
- Place of Presentation
  京都
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-23240049
[Presentation] Tardbp欠損マウスのmRNA選択的スプライシングと組織特異的な多様性Tardbp alternatively spliced mRNA and tissue-specific variation in heterozygous Tardbp-deficient mice2011
- Author(s)
  廣川祥子, 佐藤俊哉, 石原知彦, 藤野赳至, 近藤千草, 横山峯介, 崎村健司, 西澤正豊, 小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] Alteration of snRNAs in amyotrophic lateral sclerosis2011
- Author(s)
  T.ISHIHARA, A.SHIGA, A.KAKITA, A.YOKOSEKI, M.NISHIZAWA, H.TAKAHASHI, O.ONODERA
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Tardbp欠損マウスのmRNA選択的スプライシングと組織特異的な多様性 Tardbp alternatively spliced mRNA and tissue-specific variation in heterozygous Tardbp-deficient mice2011
- Author(s)
  廣川祥子, 佐藤俊哉, 石原知彦, 藤野赳至, 近藤千草, 横山峯介, 崎村健司, 西澤正豊, 小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Aberrant splicing ofPOLDIP3 gene in motor neuron with ALS2011
- Author(s)
  A. SHIGA1, T. ISHIHARA1, A.MIYASHITA1, T. KATO1, M. KUWABARA1, A. YOKOSEKI2, R. KUWANO1, A. KAKITA1,H. TAKAHASHI1, M. NISHIZAWA1, O.ONODERA1
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D. C.
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] ALS関連蛋白TDP-43の自己発現調節機能に関与するスプライシング因子の検討Splicing factors involved in an autoregulation of the ALS-associated protein TDP-432011
- Author(s)
  桑原美咲, 石原智彦, 志賀篤, 今野卓哉, 小山哲秀, 西澤正豊, 小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] ALS関連蛋白TDP-43の自己発現調節機能に関与するスプライシング因子の検討Splicing factors involved in an autoregulation of the ALS-associated protein TDP-432011
- Author(s)
  桑原美咲, 石原智彦, 志賀篤, 今野卓哉, 小山哲秀, 西澤正豊, 小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] Tardbp欠損マウスのmRNA選択的スプライシングと組織特異的な多様性Tardbp alternatively spliced mRNA andtissue-specific variation inheterozygous Tardbp-deficient mice2011
- Author(s)
  廣川祥子,佐藤俊哉,石原知彦,藤野赳至,近藤千草,横山峯介,崎村健司,西澤正豊,小野寺理
- Organizer
  分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] Alteration of snRNAs in amyotrophic lateral sclerosis2011
- Author(s)
  T.ISHIHARA, A.SHIGA, A.KAKITA, A.YOKOSEKI, M.NISHIZAWA, H.TAKAHASHI, O.ONODERA
- Organizer
  6th Brain Research Conference : RNA-Binding Proteins in Neurological Disease
- Place of Presentation
  Washington, D.C.
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Alteration of snRNAs inamyotrophic lateral sclerosis2011
- Author(s)
  T. ISHIHARA, A. SHIGA, A. KAKITA A.YOKOSEKI, M. NISHIZAWA, H. TAKAHASHI, O. ONODERA
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, D. C.
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] TDP-43 depletion causes splicing defects in the genes associated with endomembrane system.2010
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MIYASHITA, M.YOKOO, Y.ARIIZUMI, A.YOKOSEKI, R.KUWANO, M.NISHIZAWA, O.ONODERA
- Organizer
  Neuroscience 2010
- Place of Presentation
  San Diego
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] Cytoplasmic C-Terminus TDP-43 Aggregate Leads to Increased Phosphorylation of Full-Length TDP-43 in Culture Cell2010
- Author(s)
  Ariizumi, Y Ishihara, T.Yokoo, M.Shiga, A.Yokoseki, A.Onodera, O.Nishizawa, M
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] 遺伝性血管性認知症2010
- Author(s)
  小野寺理
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] TGF-β経路は遺伝性脳小血管病で特異的に活性化される(TGF-βpathway is specifically activated in hereditary cerebral small-vessel disease)2010
- Author(s)
  二本松萌,志賀篤,野崎洋明,西澤正豊,小野寺理
- Organizer
  日本生化学会大会・日本分子生物学会年会合同大会83回・33回
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] Alteration of snRNAs in Amyotrophic Lateral Sclerosis2010
- Author(s)
  Ishihara, T.Shiga, A.Kakita, A.Yokoseki, A.Nishizawa, M.Takahashi, H.Onodera, O
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] 遺伝性血管性認知症2010
- Author(s)
  小野寺理
- Organizer
  第29回日本認知症学会
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] Novel molecular mechanism for hereditary cerebral small-vessel disease2010
- Author(s)
  小野寺理
- Organizer
  BMB2010
- Place of Presentation
  神戸(招待講演)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] Cytoplasmic C-Terminus TDP-43 Aggregate Leads to Increased Phosphorylation of Full-Length TDP-43 in Culture Cell2010
- Author(s)
  Ariizumi, Y..Ishihara ; T.Yokoo, M.Shiga, A.Yokoseki, A.Onodera, O.Nishizawa, M
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Cytoplasmic C-Terminus TDP-43 Aggregate Leads to Increased Phosphorylation of Full-Length TDP-43 in Culture Cell2010
- Author(s)
  Ariizumi, Y.Ishihara, T.Yokoo, M.Shiga, A.Yokoseki, A.Onodera, O.Nishizawa, M
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] TDP-43 depletion causes splicing defects in the genes associated with endomemb rane system.2010
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MIYASHITA, M.YOKOO, Y..ARIIZUMI, A.YOKOSEKI, R.KUWANO, M.NISHIZAWA, O.ONODERA
- Organizer
  Neuroscience 2010
- Place of Presentation
  San Diego
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] ALS-TDP43の臨床と病理2010
- Author(s)
  小野寺理
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PUBLICLY-22113506
[Presentation] Alteration of snRNAs inAmyotrophic Lateral Sclerosis2010
- Author(s)
  Ishihara, T. Shiga, A. Kakita A.Yokoseki A. Nishizawa M. Takahashi, H.Onodera O
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] HTRA1 controls BMP2/4 signaling via cleavage of proBMP2/4 : Implication for molecular pathogenesis of hereditary cerebral small vessel disease2010
- Author(s)
  H.NOZAKI, A.SHIGA, M.NIHONMATSU, A.KOYAMA, O.ONODERA, M.NISHIZAWA
- Organizer
  NEUROSCIENCE 2010
- Place of Presentation
  San Diego
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] Alteration of snRNAs in Amyotrophic Lateral Sclerosis2010
- Author(s)
  Ishihara, T.Shiga, A.Kakita, A.Yokoseki, A.Nishizawa, M.Takahashi, H.Onodera, O
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] HTRA1 controls BMP2/4 signaling via cleavage of proBMP2/42010
- Author(s)
  H NOZAKI, A. SHIGA, M. NIHONMATSU, A. KOYAMA, O ONODERA, M. NISHIZAWA
- Organizer
  Implication for molecular pathogenesis of hereditary cerebral small vessel disease NEUROSCIENCE 2010
- Place of Presentation
  San Diego.USA
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] Novel molecular mechanism for hereditary cerebral small-vessel disease2010
- Author(s)
  小野寺理
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] TDP-43 depletion causes splicingdefects in the genes associated withendomembrane system2010
- Author(s)
  A. SHIGA, T. ISHIHARA, A. MIYASHITA,M. YOKOO, Y. ARIIZUMI, A. YOKOSEKI,R. KUWANO, M. NISHIZAWA, O. ONODERA
- Organizer
  Neuroscience 2010 Saturday
- Place of Presentation
  SanDiego
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] TDP-43 depletion causes splicing defects in the genes associated with endomemb rane system.2010
- Author(s)
  A.SHIGA, T.ISHIHARA, A.MWASHITA, M.YOKOO, Y ARIIZUMI, A.YOKOSEKI, R.KUWANO, M.NISHIZAWA, O.ONODERA
- Organizer
  Neuroscience 2010
- Place of Presentation
  San Diego
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Alteration of snRNAs in Amyotrophic Lateral Sclerosis2010
- Author(s)
  Ishihara, T.Shiga, A.Kakita, A.Yokoseki, A.Nishizawa, M.Takahashi, H.Onodera, O
- Organizer
  AAN 2010
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Cytoplasmic C-Terminus TDP-43 Aggregate Leads to Increased Phosphorylation of Full-LengthTDP-43 in Culture Cell2010
- Author(s)
  Ariizumi, Y. Ishihara, T. Yokoo, M.Shiga, A. Yokoseki A. Onodera O.Nishizawa M
- Organizer
  AAN
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-22249036
[Presentation] TGF-β経路は遺伝性脳小血管病で特異的に活性化される(TGF-β pathway is specifically activated in hereditary cerebral small-vessel disease)2010
- Author(s)
  二本松萌, 志賀篤, 野崎洋明, 西澤正豊, 小野寺理
- Organizer
  日本生化学会大会・日本分子生物学会年会合同大会83回・33回
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22390174
[Presentation] 脊髄小脳変性症の分子病態機序の解明2009
- Author(s)
  小野寺理
- Organizer
  第50回日本神経学会
- Place of Presentation
  仙台
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-19390236
[Presentation] 疾患関連変異型APTXの蛋白不安定化機序の解明佐藤達哉(新潟大学学脳研究所神経内科)2009
- Author(s)
  小山哲秀, 横関明男, 他田正義, 小野寺理, 西澤正豊
- Organizer
  日本神経学会総会
- Place of Presentation
  仙台
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-19390236
[Presentation] 疾患関連変異型アプラタキシンの核小体局在障害とその機序の解明2008
- Author(s)
  佐藤達哉, 小山哲秀, 横関明男, 他田正義, 小野寺理, 西澤正豊
- Organizer
  日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19390236
[Presentation] Aprataxinは神経細胞においてDNA単鎖切断損傷修復に関与する2008
- Author(s)
  他田正義, 佐藤達哉, 横関明男, 小山哲秀, 志賀篤, 高橋哲哉, 小宅睦郎, 五十嵐修一, 佐藤俊哉, 辻省次, 西澤正豊, 小野寺理
- Organizer
  日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19390236
[Presentation] AOA1/EAOHの病態機序における核小体局在の意義2007
- Author(s)
  小野寺理, 小山哲秀, 横関明男, 他田正義, 間由希, 五十嵐修一, 西澤正豊
- Organizer
  日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-19390236
[Presentation] EAOHの病因蛋白aprataxinは校正機能を有する3'-5'exonucleaseである2007
- Author(s)
  他田正義, 横関明男, 高橋哲哉, 五十嵐修一, 西澤正豊, 小野寺理
- Organizer
  日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-19390236
[Presentation] EAOH/AOA1における遺伝子変異と臨床症状の検討2007
- Author(s)
  横関明男, 岩淵潔, 丸田恭子, 西澤正豊, 小野寺理
- Organizer
  日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-16
- Data Source
  KAKENHI-PROJECT-19390236
[Presentation] 人工制限酵素による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，笹岡俊邦，西澤正豊，小野寺理，横山峯介．
- Organizer
  第43回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター（新潟県）
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] Coordinated autoregulation of TDP-43 and its implication for TDP-43 pathology
- Author(s)
  須貝章弘　小山哲秀　加藤泰介　志賀篤　今野卓哉　小山美咲　石原智彦　西澤正豊　小野寺理
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Invited
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Analysis of intracellular distribution of TDP-43 mRNA in affected spinal motor neuron with ALS
- Author(s)
  Kato T, Koyama A, Sugai A, Toyoshima Y, Takahashi H, Nishizawa M, Onodera O
- Organizer
  The 37th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] ALS関連蛋白TDP-43の自己発現調節機能に関与するスプライシング因子の検討
- Author(s)
  桑原美咲,石原智彦,志賀篤,今野卓哉,小山哲秀,西澤正豊,小野寺理
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PROJECT-22659169
[Presentation] Analysis of the physiological function of TDP-43 using the C-terminal deficient mice established by zinc finger nuclease
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，笹岡俊邦，小野寺理，横山峯介．
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場（神戸）
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] Update in amyotrophic lateral sclerosis
- Author(s)
  Osamu Onodera, Masatoyo Nishizawa, Hitoshi Takahashi
- Organizer
  The XVIII International Congress of Neuropathology.
- Place of Presentation
  Rio de Janeiro, Brazil Sheraton Rio Hotel & Resort
- Year and Date
  2014-09-14 – 2014-09-18
- Invited
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] GFβ1過剰発現マウスでは脳小血管壁細胞の異常をきたす
- Author(s)
  関根有美、加藤泰介、野崎洋明、廣川祥子、佐藤俊哉、志賀篤、笹岡敏邦、西澤正豊、小野寺理
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡市　福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25293200
[Presentation] 筋萎縮性側索硬化症のTDP-43皮質組織像の多様性：臨床病理および生化学的解析
- Author(s)
  竹内亮子, 他田真理, 志賀　篤, 今野卓哉, 豊島靖子, 小野寺理, 西澤正豊, 柿田明美, 高橋　均
- Organizer
  日本神経病理学会
- Place of Presentation
  学術総合センター、東京
- Year and Date
  2014-06-05 – 2014-06-07
- Data Source
  KAKENHI-PROJECT-26640029
[Presentation] RNA metabolism and ALS.
- Author(s)
  Osamu Onodera
- Organizer
  The 37th Annual Meeting of the Japan Neuroscience Society.
- Place of Presentation
  横浜　パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-25670417
[Presentation] Droplet digital PCR system fascilitate to clone the genome-edited iPS cells.
- Author(s)
  Atsushi Shiga, Masatoyo Nishizaw, Osamu Onodera.
- Organizer
  Molecular Med Tri-Con 2015
- Place of Presentation
  San Francisco CA USA
- Year and Date
  2015-02-16 – 2015-02-18
- Data Source
  KAKENHI-PROJECT-25670417
[Presentation] The reduction of minor spliceosome and aberrant splicing in ALS.
- Author(s)
  T. Ishihara., A. Koyama M., Nishizawa. O. Onodera
- Organizer
  Cell Symposium
- Place of Presentation
  Berkeley, CA, USA
- Year and Date
  2014-10-19 – 2014-10-21
- Data Source
  KAKENHI-PROJECT-25670417
[Presentation] Aberration of the spliceosome in amyotrophic lateral sclerosis
- Author(s)
  石原智彦，柿田明美，高橋均，小野寺理，西澤正豊
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Invited
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Droplet digital PCR system fascilitate to clone the genome-edited iPS cells.
- Author(s)
  Atsushi Shiga, Masatoyo Nishizaw, Osamu Onodera.
- Organizer
  Molecular Med Tri-Con 2015
- Place of Presentation
  San Francisco CA　Mosco center
- Year and Date
  2015-02-16 – 2015-02-18
- Invited
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Update in amyotrophic lateral sclerosis
- Author(s)
  Osamu Onodera, Masatoyo Nishizawa, Hitoshi Takahashi
- Organizer
  The XVIII International Congress of Neuropathology. ICN 2014
- Place of Presentation
  Rio de Janeiro, Brazil
- Year and Date
  2014-09-14 – 2014-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Molecular mechanism of nucleolus localization of aprataxin, causative protein for neurodegenerative disorder
- Author(s)
  T. SATO, A. KOYAMA, M. TADA, S. ATSUSHI, S. IGARASHI, M. NISHIZAWA, *O. ONODERA
- Data Source
  KAKENHI-PROJECT-19390236
[Presentation] Endogenous TDP-43 over-expression model with disrupted auto-regulation
- Author(s)
  Akihiro Sugai, Taisuke Kato, Akihide Koyama, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  10th Annual Meeting of the Oligonucleotide Therapeutics Society.
- Place of Presentation
  Hilton San Diego Resort & Spa, San Diego, California USA
- Year and Date
  2014-10-12 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-25670417
[Presentation] 筋萎縮性側索硬化症における嗜銀顆粒性認知症の共存について
- Author(s)
  相馬健一、付　永娟、若林孝一、小野寺　理、柿田明美、高橋　均
- Organizer
  第５２回日本神経病理学会総会学術研究会
- Place of Presentation
  京都テルサ（京都市）
- Data Source
  KAKENHI-PROJECT-23659184
[Presentation] TDP-43 C-terminal deficient mice exhibit a loss-of-function phenotype with up-regulated Tardbp mRNA.
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，笹岡俊邦，小野寺理，横山峯介．
- Organizer
  第5回新潟大学脳研究所共同研究拠点国際シンポジウム
- Place of Presentation
  新潟大学脳研究所（新潟県・新潟市）
- Year and Date
  2015-03-05 – 2015-03-06
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] RNA metabolism and ALS
- Author(s)
  Osamu Onodera
- Organizer
  The 37th Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  横浜パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Invited
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 人工制限酵素による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，笹岡俊邦，西澤正豊，小野寺理，横山峯介．
- Organizer
  第4回新潟大学脳研究所共同研究拠点国際シンポジウム
- Place of Presentation
  新潟大学脳研究所統合脳機能研究センター（新潟県）
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] The reduction of minor spliceosome and aberrant splicing in ALS.
- Author(s)
  T. Ishihara., A. Koyama M., Nishizawa. O. Onodera.
- Organizer
  Cell Symposium
- Place of Presentation
  Berkeley, CA, USA
- Year and Date
  2014-10-19 – 2014-10-21
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] Clinicopathologic analysis of TDP-43 expression in the cerebral cortex in ALS
- Author(s)
  Takeuchi R, Tada M, Shiga A, Konno T, Toyoshima Y, Onodera O, Nishizawa M, Kakita A, Takahashi H.
- Organizer
  The 66th Annual Meeting of American Academy of Neurology
- Place of Presentation
  Pennsylvania Convention Center, Philadelphia, USA
- Year and Date
  2014-04-27 – 2014-04-29
- Data Source
  KAKENHI-PROJECT-26640029
[Presentation] The reduction of minor spliceosome and aberrant splicing in ALS.
- Author(s)
  T. Ishihara., A. Koyama M., Nishizawa. O. Onodera.
- Organizer
  Cell Symposium
- Place of Presentation
  Berkeley, CA, USA　Claremont Hotel & Spa
- Year and Date
  2014-10-19 – 2014-10-21
- Invited
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] Endogenous TDP-43 over-expression model with disrupted auto-regulation
- Author(s)
  3.Akihiro Sugai, Taisuke Kato, Akihide Koyama, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  10th Annual Meeting of the Oligonucleotide Therapeutics Society.
- Place of Presentation
  Hilton San Diego Resort & Spa, San Diego, California
- Year and Date
  2014-10-12 – 2014-10-15
- Invited
- Data Source
  KAKENHI-PLANNED-26117006
[Presentation] 人工制限酵素による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，廣川祥子，永田史也，前田宜俊，藤澤信義，西澤正豊，小野寺理，横山峯介．
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25461271
[Presentation] Update in amyotrophic lateral sclerosis
- Author(s)
  Onodera O, Nishizawa M, Takahashi H
- Organizer
  The XVIII International Congress of Neuropathology
- Place of Presentation
  Sheraton Rio Hotel & Resort, Rio de Janeiro, Brazil
- Year and Date
  2014-09-14 – 2014-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-26250017
[Presentation] Update in amyotrophic lateral sclerosis:
- Author(s)
  Osamu Onodera, Masatoyo Nishizawa, Hitoshi Takahashi
- Organizer
  The XVIII International Congress of Neuropathology.
- Place of Presentation
  Rio de Janeiro, Brazil,
- Year and Date
  2014-09-14 – 2014-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-25670417
[Presentation] Endogenous TDP-43 over-expression model with disrupted auto-regulation
- Author(s)
  Akihiro Sugai, Taisuke Kato, Akihide Koyama, Masatoyo Nishizawa, Osamu Onodera
- Organizer
  10th Annual Meeting of the Oligonucleotide Therapeutics Society.
- Place of Presentation
  Hilton San Diego Resort & Spa, San Diego, California
- Year and Date
  2014-10-12 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-25253065
[Presentation] 人工ヌクレアーゼ技術による内在性TDP-43遺伝子改変と筋萎縮性側索硬化症モデルへの応用
- Author(s)
  佐藤俊哉，小田佳奈子，酒井清子，西澤正豊，小野寺理，横山峯介，笹岡俊邦．
- Organizer
  第44回新潟神経学夏期セミナー
- Place of Presentation
  新潟大学脳研究所（新潟県・新潟市）
- Year and Date
  2014-07-31 – 2014-08-02
- Data Source
  KAKENHI-PROJECT-25461271

1. TOYOSHIMA Yasuko (20334675)

# of Collaborated Projects: 12 results

# of Collaborated Products: 22 results
2. TAKAHASHI Hitoshi (90206839)

# of Collaborated Projects: 10 results

# of Collaborated Products: 39 results
3. KAKITA Akiyoshi (80281012)

# of Collaborated Projects: 7 results

# of Collaborated Products: 57 results
4. SATOU Toshiya (90359703)

# of Collaborated Projects: 6 results

# of Collaborated Products: 20 results
5. TSUJI Shoji (70150612)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
6. GOTO Jun (10211252)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
7. OYAKE Mutsuo (70313559)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
8. 加藤泰介 (30598496)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
9. TAKAHASHI Yuji (00372392)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
10. SAKIMURA Kenji (40162325)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
11. KUWANO Ryozo (20111734)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
12. KOYAMA Akihide (90622209)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
13. OZAWA Tetsutaro (10377153)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. YOKOYAMA Minesuke (40090930)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. NISHIZAWA Masatoyo (80198457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 36 results
16. NOZAKI Hiroaki (20547567)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
17. Tada Masayoshi (10467079)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
18. TADA Mari (30646394)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
19. YAMADA Mitsunori (30240039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 清水宏 (40608767)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
21. MURAYAMA Shigeo (50183653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. TAKAHASHI Toshiaki (70377191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
23. TAN ChenーFeng (40447610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
24. ABE Manabu (10334674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TERAJIMA Kenshi (00377160)

# of Collaborated Projects: 1 results

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26. AKAZAWA Kouhei (10175771)

# of Collaborated Projects: 1 results

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27. ISHIHARA Tomohiko (70612232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
28. IKEUCHI Takeshi (20372469)

# of Collaborated Projects: 1 results

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29. KOBAYASHI Hisashi (30303168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. IGARASHI Shuichi (60345519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. Fujii Masahiro (30183099)

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# of Collaborated Products: 1 results
32. Komatsu Masaaki (90356254)

# of Collaborated Projects: 1 results

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33. KODERA YOSHIO (60265733)

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34. Yano Masato (20445414)

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# of Collaborated Products: 5 results
35. 百瀬義雄 (30359624)

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36. 横関明男 (90515719)

# of Collaborated Projects: 1 results

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37. 清水潤 (40260492)

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38. 成瀬聡 (70313541)

# of Collaborated Projects: 1 results

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39. 田中英智 (80612225)

# of Collaborated Projects: 1 results

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40. 矢野佳芳 (60397320)

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41. 上村昌寛 (00836710)

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42. 五十嵐博中 (20231128)

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43. 今野卓哉 (20837372)

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44. 金澤雅人 (80645101)

# of Collaborated Projects: 1 results

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45. 塚田啓道 (40794087)

# of Collaborated Projects: 1 results

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46. 齋藤理恵 (80829078)

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47. SACHIKO Hirokawa

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48. Takahashi Masahiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
49. Kageyama Shun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. Hara Toshifumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
51. Higuchi Masaya

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
52. Saito Kousuke

# of Collaborated Projects: 1 results

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53. Katsuragi Yoshinori

# of Collaborated Projects: 1 results

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54. Kakihana Taichi

# of Collaborated Projects: 1 results

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55. KATSUNO Masahisa

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56. MORISHITA Shinichi

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57. MIZUNO Toshiki

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58. MIZUTA Ikuko

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59. 早川佳芳

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60. 松井秀彰

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61. 熱田直樹

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62. 祖父江元

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# of Collaborated Products: 1 results
63. 中村亮一

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64. 藤内玄規

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65. 森満

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# of Collaborated Products: 1 results
66. 豊田敦

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67. 松本雅記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

onodera osamu 小野寺 理

ONODERA Osamu 小野寺 理

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Identification of cell groups that perturb the extracellular matrix of cerebral small vessel disease and deciphering their regulatory mechanisms.Principal Investigator

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Approach to neurodegenerative disorders by elucidation of the excretion pathway of the brain.Principal Investigator

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Elucidation of the significance of MAPT polymorphism associated with sporadic tauopathies by using genome editing method.Principal Investigator

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Strategies for overcoming vascular dementia focusing on dynamic functions of cerebral small vessels.Principal Investigator

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Mechanism of protein aging from the point of turbulence of nucleic acid metabolism or its exclusion mechanism.Principal Investigator

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U12依存性スプライシングとALSサーキットパソロジーPrincipal Investigator

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Approach to cerebral small vessel disease: lesson from CARASIL.Principal Investigator

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onodera osamu 小野寺理

ONODERA Osamu 小野寺理