kadowaki Makoto 門脇真

… Alternative Names

Kadowaki Makoto 門脇真

KADOWAKI Makoto 門脇真

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Researcher Number	20305709
Other IDs
Affiliation (Current)	2025: 富山大学, 学術研究部教育研究推進系, 特別研究教授
Affiliation (based on the past Project Information) *help	2023: 富山大学, 学術研究部教育研究推進系, 特別研究教授 2021 – 2022: 富山大学, 和漢医薬学総合研究所, 名誉教授 2020: 富山大学, 学術研究部薬学・和漢系, 名誉教授 2016 – 2018: 富山大学, 和漢医薬学総合研究所, 教授 2009 – 2014: University of Toyama, 和漢医薬学総合研究所, 教授 … More 2012: 富山大学, 和漢医薬総合研究所, 教授 2005 – 2007: University of Toyama, Institute of Natural Medicine, Professor, 和漢医薬学総合研究所, 教授 2004: Institute of Natural Medicine, Division of Gastrointestinal Pathophysiology, Professor, 和漢薬研究所, 教授 2002 – 2003: 奈良県立医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine) / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Applied pharmacology / Environmental physiology (including Physical medicine and Nutritional physiology) Except Principal Investigator Nerve anatomy/Neuropathology / Gastroenterology / Environmental pharmacy
Keywords	Principal Investigator 漢方薬 / リポジショニング / COX-2 / COX-1 / 樹状細胞 / 食物アレルギー / 腸管粘膜免疫系 / 東洋医学 / 粘膜修復 / 腸管マクロファージ … More / IL-10 / 再燃 / nNOS陽性腸管神経 / 神経細胞死 / 未病遺伝子 / 炎症性腸疾患（IBD） / NO神経 / 神経新生 / マスト細胞 / 未病 / DNB解析 / 炎症性腸疾患 / 標的タンパク質 / 和漢医薬学 / 実験薬理学的検証 / 標的タンパク質探索 / 結合シミュレーション / 機械学習手法 / インシリコ / in silico結合シミュレーション / 機械学習 / 医薬ビッグデータ / 複雑系 / ドラッグ・リポジショニング / 大腸炎関連発癌 / 寛解期 / 慢性大腸炎関連発癌 / 経時的全遺伝子発現解析 / 数理解析 / 疾病前状態の予測 / 急性大腸炎 / 大建中湯 / cytokine / type-2 helper T cell / intestinal mucosal immune system / nicotinic acetylcholine receptor s / oxazolone / ulcerative Colitis / ニコチン受容体 / サイトカイン / Th2 / ニコチン性アセチルコリン受容体 / オキサゾロン / 潰瘍性大腸炎 / calcitonin gene-related peptide (CGRP) / Immunohistochemistry / transient receptor potential vanilloid 1 (TRPV1) / capsaicin / food allergy / rat intestine / 除神経 / 粘膜下神経叢 / 筋層間神経経叢 / 運動 / 知覚神経 / オブアルブミン / vanilloid receptor subtype 1 / 腸管 / ラット / 植物アレルギー / CGRP / 免疫組織化学 / TRPV1 / キャプサイシン / ラット腸管 / 炎症性疾患 / アレルギー / 自己免疫疾患 / 創薬研究 / 探索研究 / 遊走 / CD25 / Foxp3 / 末梢性免疫寛容 / 活性化T細胞 / 制御性T細胞 / 葛根湯 … More Except Principal Investigator SP / CGRP / Wistar rat / immunohistochemistry / lower esophageal sphincter / esophagus / sensory nerve / capsaicin receptor / 抑制反射機構 / ウィスター・ラット / 抑制性反射 / 一酸化窒素作動性神経 / タキキニン / 食道壁在性神経細胞 / 下部食道括約筋 / ラット / 免疫組織化学 / Fos / サブスタンスP(SP) / 知覚神経 / 迷走神経 / キャプサイシン・レセプター / autonomic rhythmicity / IP_3 receptor / ryanodine receptor / sarcoplasmic reticulum / mitochondria / Ca channel / interstitial cells of Cajal / pacemaker cell / 自動運動 / IP_3受容体 / リアノジン受容体 / 筋小胞体 / ミトコンドリア / Caチャネル / カハールの間質細胞 / ペースメーカー細胞 / 党参 / 龍胆 / 大黄 / 秦ギョウ / 分子系統学 / 抗炎症 / 抗アレルギー / エゾウコギ / 薬用植物学 / 国際協力 / アレルギー疾患 / 痴呆 / Gentiana属生薬 / 刺五加 / 芍薬 / 品質評価 / 薬用植物 Less

Novel Inflammatory Disease Treatment Based on Scientific Prediction of Mebyo by Integrating Kampo Medice and Mathematical InformaticsPrincipal Investigator
- Principal Investigator
  
  Kadowaki Makoto
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  University of Toyama
Daikenchuto, a traditional Japanese Kampo medicine, suppresses colonic tumorigenesis associated with chronic colitis in micePrincipal Investigator
- Principal Investigator
  
  Kadowaki Makoto
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Toyama
Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseasesPrincipal Investigator
- Principal Investigator
  
  Kadowaki Makoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Toyama
Construction of a program for sustainable use of traditional medicines, based on integrated study of genetic, chemical and pharmacological diversity of medicinal plants
- Principal Investigator
  
  KOMATSU Katsuko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Toyama
Examination of the effects of constituents of traditional Japanese herbal (Kampo) medicines on the migration of plasmacytoid dendritic cells to develop a new therapeutic targetPrincipal Investigator
- Principal Investigator
  
  KADOWAKI MAKOTO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
Immunological tolerance induced by Kampo medicine kakkonto through the regulation of helper T cell differentiation in the mucosal immune system of the intestine.Principal Investigator
- Principal Investigator
  
  KADOWAKI Makoto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
Pathophysiological Role of Cholinergic Anti-inflammatory Pathway via Nicotinic Acetylcholine Receptors in Experimental Ulcerative ColitisPrincipal Investigator
- Principal Investigator
  
  KADOWAKI Makoto
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Toyama
Inhibitory reflex system by capsaicin-sensitive sensory nerves in lower esophageal sphincter
- Principal Investigator
  
  KURAMOTO Hirofumi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto Institute of Technology
Studies on colonic autonomic rhythmicity and its pacemaker mechanism in pathological model animals
- Principal Investigator
  
  TAKAKI Miyako
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Nara Medical University
Food allergy and immunologic disease in the intestine : the role of primary afferent neurons in the intestinePrincipal Investigator
- Principal Investigator
  
  KADOWAKI Makoto
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
  Nara Medical University

[Journal Article] Application of the Dynamical Network Biomarker Theory to Raman Spectra2022
- Author(s)
  Haruki Takayuki、Yonezawa Shota、Koizumi Keiichi、Yoshida Yasuhiko、Watanabe Tomonobu M.、Fujita Hideaki、Oshima Yusuke、Oku Makito、Taketani Akinori、Yamazaki Moe、Ichimura Taro、Kadowaki Makoto、Kitajima Isao、Saito Shigeru
- Journal Title
  
  Biomolecules
  
  Volume: 12 Issue: 12 Pages: 1730-1730
- DOI
  10.3390/biom12121730
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05409, KAKENHI-PROJECT-20K07098, KAKENHI-PUBLICLY-21H05590
[Journal Article] Neuro-immune crosstalk and food allergy: Focus on enteric neurons and mucosal mast cells2022
- Author(s)
  Kadowaki Makoto, Yamamoto Takeshi, Hayashi Shusaku
- Journal Title
  
  Allergol. Int.
  
  Volume: 71 Issue: 3 Pages: 278-287
- DOI
  10.1016/j.alit.2022.03.004
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Cholinergic anti-inflammatory pathway ameliorates murine experimental Th2-type colitis by suppressing the migration of plasmacytoid dendritic cells2022
- Author(s)
  Kanauchi Yuya、Yamamoto Takeshi、Yoshida Minako、Zhang Yue、Lee Jaemin、Hayashi Shusaku、Kadowaki Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 54-54
- DOI
  10.1038/s41598-021-04154-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098, KAKENHI-PROJECT-21K06593
[Journal Article] Identification of key pathways and gene expression in the activation of mast cells via calcium flux using bioinformatics analysis2021
- Author(s)
  Wang X, Yamamoto T, Kadowaki M, Yang Y
- Journal Title
  
  BIOCELL
  
  Volume: 45 Issue: 2 Pages: 395-415
- DOI
  10.32604/biocell.2021.012280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Pathophysiological Roles of Neuro-Immune Interactions between Enteric Neurons and Mucosal Mast Cells in the Gut of Food Allergy Mice2021
- Author(s)
  Yashiro Tomoe、Ogata Hanako、Zaidi Syed Faisal、Lee Jaemin、Hayashi Shusaku、Yamamoto Takeshi、Kadowaki Makoto
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 7 Pages: 1586-1586
- DOI
  10.3390/cells10071586
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Suppression of plasmacytoid dendritic cell migration to colonic isolated lymphoid follicles abrogates the development of colitis2021
- Author(s)
  Zhang Yue、Yamamoto Takeshi、Hayashi Shusaku、Kadowaki Makoto
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 141 Pages: 111881-111881
- DOI
  10.1016/j.biopha.2021.111881
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Morphological elucidation of short-chain fatty acid receptor GPR41-positive enteric sensory neurons in the colon of mice with dextran sulfate sodium-induced colitis2020
- Author(s)
  Hertati Ai、Hayashi Shusaku、Ogata Hanako、Miyata Kana、Kato Ryo、Yamamoto Takeshi、Kadowaki Makoto
- Journal Title
  
  Heliyon
  
  Volume: 6 Issue: 12 Pages: e05647-e05647
- DOI
  10.1016/j.heliyon.2020.e05647
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-20K07098, KAKENHI-PROJECT-17KK0166
[Journal Article] Isoflavones Suppress Cyp26b1 Expression in the Murine Colonic Lamina Propria2020
- Author(s)
  Yamamoto Takeshi、Nagata Yuka、Hayashi Shusaku、Kadowaki Makoto
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 12 Pages: 1945-1949
- DOI
  10.1248/bpb.b20-00355
- NAID
  130007948731
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Ginger Increases ALDH1A1 Expression and Enhances Retinoic Acid Signaling in a Human Colonic Epithelial Cell Line2020
- Author(s)
  Nagata Y, Yamamoto T, Kadowaki M.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 66 Issue: 5 Pages: 462-467
- DOI
  10.3177/jnsv.66.462
- NAID
  130007932347
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2020-10-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Therapeutic Benefit in Allergic Dermatitis Derived from the Inhibitory Effect of Byakkokaninjinto on the Migration of Plasmacytoid Dendritic Cells2020
- Author(s)
  Yamamoto Takeshi、Zhang Yue、Kigasawa Ai、Hayashi Shusaku、Kadowaki Makoto
- Journal Title
  
  Evidence-Based Complementary and Alternative Medicine
  
  Volume: 2020 Issue: 1 Pages: 1-10
- DOI
  10.1155/2020/9532475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Interleukin-4 Receptor α Subunit Deficiency Alleviates Murine Intestinal Inflammation In Vivo Through the Enhancement of Intestinal Mucosal Barrier Function2020
- Author(s)
  Hertati Ai、Hayashi Shusaku、Ogawa Yudai、Yamamoto Takeshi、Kadowaki Makoto
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 11 Pages: 573470-573470
- DOI
  10.3389/fphar.2020.573470
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-20K07098, KAKENHI-PROJECT-17KK0166
[Journal Article] Genetic polymorphism of Japanese cultivated Rheum species in the internal transcribed spacer region of nuclear ribosomal DNA.2019
- Author(s)
  Asanuma M., Zhu S., Okura N., Cai S.Q., Yoshimatsu K., Komatsu K.
- Journal Title
  
  J Nat Med.
  
  Volume: 73 Issue: 3 Pages: 541-554
- DOI
  10.1007/s11418-019-01298-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06716, KAKENHI-PROJECT-20K07098
[Journal Article] KampoDB, database of predicted targets and functional annotations of natural medicines.2018
- Author(s)
  Sawada R, Iwata M, Umezaki M, Usui Y, Kobayashi T, Kubono T, Hayashi S, Kadowaki M, Yamanishi Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 11216-11216
- DOI
  10.1038/s41598-018-29516-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05276
[Journal Article] Improvement of Therapeutic Efficacy of Oral Immunotherapy in Combination with Regulatory T Cell-Inducer Kakkonto in a Murine Food Allergy Model.2017
- Author(s)
  Nagata Y, Yamamoto T, Hayashi M, Hayashi S, Kadowaki M.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 1 Pages: e0170577-e0170577
- DOI
  10.1371/journal.pone.0170577
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09234, KAKENHI-PROJECT-15K18873, KAKENHI-PROJECT-16H05276
[Journal Article] PI3K p85alpha Subunit-deficient Macrophages Protect Mice from Acute Colitis due to the Enhancement of IL-10 Production.2017
- Author(s)
  Hayashi S., Hamada T., Zinsou D. G. A., Oshiro M., Itoi K., Yamamoto T., Kadowaki M.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 6187-6187
- DOI
  10.1038/s41598-017-06464-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-16K15408, KAKENHI-PROJECT-15K18873
[Journal Article] Induction of regulatory T cells as a novel mechanism underlying the therapeutic action of kakkonto, a traditional Japanese herbal medicine, in a murine food allergy model2016
- Author(s)
  Yamamoto T, Fujiwara K, Tsubota Y, Kageyama-Yahara N, Hayashi S, Kadowaki M
- Journal Title
  
  International Archives of Allergy and Immunology
  
  Volume: 169 Issue: 3 Pages: 146-156
- DOI
  10.1159/000445433
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460891, KAKENHI-PROJECT-16H05276
[Journal Article] Anti-allergic role of cholinergic neuronal pathway via α7 nicotinic ACh receptors on mucosal mast cells in a murine food allergy model2014
- Author(s)
  Yamamoto T., Kodama T., Lee J., Utsunomiya N., Hayashi S., Sakamoto H., Kuramoto H., Kadowaki M.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: 85888-85888
- DOI
  10.1371/journal.pone.0085888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PROJECT-24790657, KAKENHI-PROJECT-25460891
[Journal Article] Shikonin, a constituent of Lithospermum erythrorhizon exhibits anti-allergic effects by suppressing orphan nuclear receptor Nr4a family gene expression as a new prototype of calcineurin inhibitors in mast cells2014
- Author(s)
  Wang X., Hayashi S., Umezaki M., Yamamoto T., Kageyama-Yahara N., Kondo T., Kadowaki M.
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 224 Pages: 117-127
- DOI
  10.1016/j.cbi.2014.10.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PROJECT-25460891
[Journal Article] Arbutin, an intracellular hydroxyl radical scavenger, protects radiation-induced apoptosis in human lymphoma U937 cells2014
- Author(s)
  Wu L. H., Li P., Zhao Q. L., Piao J. L., Jiao Y. F., Kadowaki M., Kondo T.
- Journal Title
  
  Apoptosis
  
  Volume: 19 Issue: 11 Pages: 1654-1663
- DOI
  10.1007/s10495-014-1032-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879
[Journal Article] CGRP, a neurotransmitter of enteric sensory neurons, contributes to the development of food allergy due to the augmentation of microtubule reorganization in mucosal mast cells.2014
- Author(s)
  Kim JH., Yamamoto T., Lee J., Yashiro T., Hamada T., Hayashi S., Kadowaki M.
- Journal Title
  
  Biomedical Research
  
  Volume: 35 Pages: 285-293
- NAID
  130004678584
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590879
[Journal Article] Nicotine suppresses acute colitis and colonic tumorigenesis associated with chronic colitis in mice.2014
- Author(s)
  Hayashi S., Hamada T., Zaidi SF., Oshiro M., Lee J., Yamamoto T., Ishii Y., Sasahara M., Kadowaki M.
- Journal Title
  
  Americal Journal of Physiology Gastrointestinal and Liver Physiology
  
  Volume: 307 Issue: 10 Pages: G968-G978
- DOI
  10.1152/ajpgi.00346.2013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590879
[Journal Article] Isofraxidin, a potent reactive oxygen species (ROS) scavenger, protects human leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in p53-independent manner2014
- Author(s)
  Li P., Zhao Q. L., Wu L. H., Jawaid P., Jiao Y. F., Kadowaki M., Kondo T.
- Journal Title
  
  Apoptosis
  
  Volume: 19 Issue: 6 Pages: 1043-1053
- DOI
  10.1007/s10495-014-0984-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PUBLICLY-25108503, KAKENHI-PROJECT-26670551
[Journal Article] Morphological demonstration of a vagal inhibitory pathway to the lower esophageal sphincter via nitrergic neurons in the rat esophagus.2013
- Author(s)
  Kuramoto H., Kadowaki M., Yoshida N.
- Journal Title
  
  Neurogastroenterol Motil.
  
  Volume: 25 Issue: 7 Pages: 485-94
- DOI
  10.1111/nmo.12146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590879
[Journal Article] The molecular mechanisms and gene expression profiling for shikonin-induced apoptotic and necroptotic cell death in U937 cells2013
- Author(s)
  Piao J. L., Cui Z. G., Furusawa Y., Ahmed K., Rehman M. U., Tabuchi Y., Kadowaki M., Kondo T.
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 205 Issue: 2 Pages: 119-127
- DOI
  10.1016/j.cbi.2013.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PUBLICLY-25108503
[Journal Article] TRPM2 contributes to antigen-stimulated Ca2+ influx in mucosal mast cells.2013
- Author(s)
  Oda S, Uchida K, Wang X, Lee J, Shimada Y, Tominaga M, Kadowaki M.
- Journal Title
  
  Pflugers Archiv. Eur. J. Physiol.
  
  Volume: 465 Issue: 7 Pages: 1023-1030
- DOI
  10.1007/s00424-013-1219-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249012, KAKENHI-PROJECT-23790267, KAKENHI-PROJECT-24590879
[Journal Article] TRPM2 contributes to antigen-stimulated Ca2+ influx in mucosal mast cells2013
- Author(s)
  Oda S., Uchida K., Wang X., Lee J., Shimada Y., Tominaga M., Kadowaki M.
- Journal Title
  
  Pflugers Archiv : European journal of physiology
  
  Volume: 465 Issue: 3 Pages: 895-900
- DOI
  10.1016/j.bbrc.2012.12.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PROJECT-24790657, KAKENHI-PROJECT-25460891
[Journal Article] Oral Tolerance Induced by Transfer of Food Antigens via Breast Milk of Allergic Mothers Prevents Offspring from Developing Allergic Symptoms in a Mouse Food Allergy Model2012
- Author(s)
  Yamamoto T, Tsubota Y, Kodama T, Kageyama-Yahara N, Kadowaki M
- Journal Title
  
  Clinical and Developmental Immunology Volume 2012(2012)
  
  Volume: 2012 Pages: 721085-721085
- DOI
  10.1155/2012/721085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760, KAKENHI-PROJECT-22790616
[Journal Article] Sphingosine kinase-1-dependent and -independent inhibitory effects of zanthoxyli fructus to attenuate the activation of mucosal mast cells and ameliorate food allergies in mice2012
- Author(s)
  Wang X, Kageyama-Yahara N, Hayashi S, Yamamoto T, Kadowaki M.
- Journal Title
  
  Evid Based Complement Alternat Med
  
  Volume: 2012 Pages: 862743-862743
- DOI
  10.1155/2012/862743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790616, KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PROJECT-24790657
[Journal Article] Apoptotic cell death by the novel natural compound, cinobufotalin2012
- Author(s)
  Emam H
- Journal Title
  
  Chem Biol Interact
  
  Volume: 199 Issue: 3 Pages: 154-160
- DOI
  10.1016/j.cbi.2012.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390229, KAKENHI-PROJECT-24590879
[Journal Article] Rab5a Regulates Surface Expression of Fc.EPSILON.RI and Functional Activation in Mast Cells2011
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Yamamoto T, Kadowaki M
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 34 Issue: 5 Pages: 760-763
- DOI
  10.1248/bpb.34.760
- NAID
  130000657792
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760, KAKENHI-PROJECT-22790616
[Journal Article] Rab5a regulates surface expression of FcεRI and functional activation in mast cells2011
- Author(s)
  Kageyama-Yahara N., Suehiro Y., Yamamoto T., Kadowaki M
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 34 Pages: 760-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Suppression of phospholipase Cγ1 phosphorylation by cinnamaldehyde inhibits antigen-induced extracellular calcium influx and degranulation in mucosal mast cells2011
- Author(s)
  Kageyama-Yahara N., Wang X., Katagiri T., Wang P., Yamamoto T., Tominaga M., Kadowaki M
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 416 Pages: 283-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Suppression of phospholipase Cγ1 phosphorylation by cinnamaldehyde in hibits antigen-induced extracellular calcium influx and degranulation in mucosal mast cells2011
- Author(s)
  Kageyama-Yahara N, Wang X, Katagiri T, Wang P, Yamamoto T, Tominaga M, Kadowaki M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 416 Issue: 3-4 Pages: 283-8
- DOI
  10.1016/j.bbrc.2011.11.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760, KAKENHI-PROJECT-22790616
[Journal Article] The inhibitory effect of ergosterol, a bioactive constituent of a traditional Japanese herbal medicine saireito on the activity of mucosal-type mast cells.2010
- Author(s)
  Kageyama-Yahara N., Wang P., Wang X., Yamamoto T., Kadowaki M.
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 33 Pages: 142-145
- NAID
  130000140209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Pentagalloy lglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo2010
- Author(s)
  Kageyama-Yahara N., Suehiro Y., Maeda F., Kageyama S., Fukuoka J., Katagiri T., Yamamoto T., Kadowaki M
- Journal Title
  
  FEBS Letter
  
  Volume: 584 Pages: 111-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] The inhibitory effect of ergosterol, a bioactive constituent of a traditional Japanese herbal medicine saireito on the activity of mucosal-type mast cells2010
- Author(s)
  Kageyama-Yahara N., Wang P., Wang X., Yamamoto T., Kadowaki M
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 33 Pages: 142-145
- NAID
  130000140209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Pentagalloylglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo.2010
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Maeda F, Kageyama S, Fukuoka J, Katagiri T, Yamamoto T, Kadowaki M.
- Journal Title
  
  FEBS Lett.
  
  Volume: 584 Pages: 111-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Pentagalloylglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo.2010
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Maeda F, Kageyama S, Fukuoka J, Katagiri T, Yamamoto T, Kadowaki M.
- Journal Title
  
  FEBS Lett. 584
  
  Pages: 111-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] The pathophysiological roles of COX-1 and COX-2 in the intestinal smooth muscle contractility under the anaphylactic condition.2008
- Author(s)
  Kadowaki H
- Journal Title
  
  Biomedical Research 29
  
  Pages: 113-117
- NAID
  130004724049
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590507
[Journal Article] The pathophysiological roles of COX-1 and COX-2 in the intestinal smooth muscle contractility under the anaphylactic condition2008
- Author(s)
  Kadowaki H
- Journal Title
  
  Biomedical Research (掲載確定)
- NAID
  130004724049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590507
[Journal Article] The pathophysiological roles of COX-1 and COX-2 in the intestinal smooth muscle contractility under the anaphylactic condition2006
- Author(s)
  Kadowaki, H
- Journal Title
  
  Biomedical Research 29
  
  Pages: 113-117
- NAID
  130004724049
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Journal Article] Vagus nerve stimulation preferentially induces Fos expression in nitrergic neurons of rat esophagus2006
- Author(s)
  Hirofumi Kuramoto, Makoto Kadowaki
- Journal Title
  
  Cell and Tissue Research 324(3)
  
  Pages: 361-367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500236
[Journal Article] Vagus nerve stimulationpreferentially induces Fos expression in nitrergic neurons of rat esophagus2006
- Author(s)
  Hirofumi Kuramoto, Makoto Kadowaki
- Journal Title
  
  Cell and Tissue Research (On line)
- Data Source
  KAKENHI-PROJECT-15500236
[Journal Article] Calbindin is predominantly expressed in nitrergic neurons in rat esophagus2006
- Author(s)
  Hirofumi Kuramoto, Makoto Kadowaki, Takeshi Yamamoto, Ryozo Kuwano
- Journal Title
  
  Neuroscience Letters 401(1-2)
  
  Pages: 174-177
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500236
[Journal Article] Localization of neurokinin 1 receptor (NK1R) immunoreactivity in rat esophagus2004
- Author(s)
  Hirofumi Kuramoto, Yukio Oomori Hiroshi Murabayashi, Makoto Kadowaki, Shin-Ichiro Karaki, Atsukazu Kuwahara
- Journal Title
  
  The Journal of Comparative Neurology 478(1)
  
  Pages: 1-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500236
[Journal Article] Combined determination with functional and morphological studies of origin of nerve fibers expressing transient receptor potential vanilloid 1……2004
- Author(s)
  Makoto Kadowaki, Hirofumi Kuramoto, et al.
- Journal Title
  
  Autonomic Neuroscience : Basic and Clinical 116
  
  Pages: 11-18
- Data Source
  KAKENHI-PROJECT-15500236
[Journal Article] Combined determination with functionnal and morphological studies of origin of nerve fibers expressing transient receptor potential vanilloid 1 in the myenteric plexus of the rat jejunum.2004
- Author(s)
  Makoto Kadowaki
- Journal Title
  
  Autonomic Neuroscience : Basic & Clinical 116
  
  Pages: 11-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570065
[Journal Article] Combined determination with functional and morphological studies of origin of nerve fibers expressing transient receptor potential vanilloid 1 in the myenteric plexus of the rat jejunum2004
- Author(s)
  Makoto Kadowaki, Hirofumi Kuramoto, Miyako Takaki
- Journal Title
  
  Autonomic Neuroscience Basic and Clinical 116(1)
  
  Pages: 11-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500236
[Journal Article] Combined determination with functionnal and morphological studies of origin of nerve fibers expressing transient receptor potential vanilloid 1 in the myenteric plexus of the rat jejunum.2004
- Author(s)
  Makoto Kadowaki
- Journal Title
  
  Autonomic Neuroscience-Basic & Clinical 116
  
  Pages: 11-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570065
[Journal Article] Combined determination with functional and morphological studies of origin of nerve fibers expressing transient receptor potential vanilloid 1 in the myenteric plexus of the rat jejunum.2004
- Author(s)
  Makoto Kadowaki
- Journal Title
  
  Autonomic Neroscience-Basic & Clinical 116
  
  Pages: 11-18
- Data Source
  KAKENHI-PROJECT-14570065
[Journal Article] Localization of neurokinin 1 receptor (NK1R) immunoreactivity in rat esophagus2004
- Author(s)
  Hirofumi Kuramoto, Yukio Oomori, Hiroshi Murabayashi, Makoto Kadowaki, Shin-ichiro Karaki, Atsukazu Kuwahara
- Journal Title
  
  The Journal of Comparative Neurology 478(1)
  
  Pages: 11-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500236
[Journal Article] Combined determination with functional and morphological studies of origin of nerve fibers expressing transient receptor potential vanilloid lin the myenteric plexus of the rat Jejunum2004
- Author(s)
  Makoto Kadowaki, Hirofumi Kuramoto, Miyako Takaki
- Journal Title
  
  Autonomic Neuroscience : Basic and Clinical 116(1)
  
  Pages: 11-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500236
[Presentation] Preferential Neurogenesis of Nitrergic Neurons in the Myenteric Plexus of the DSS-induced Colitis Mouse Colon Causes Colonic Dysmotility in Colitis2024
- Author(s)
  Makoto Kadowaki, Kana Miyata, Takeshi Yamamoto, Shusaku Hayashi
- Organizer
  日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] PREFERENTIAL NEUROGENESIS OF NITRERGIC NEURONS IN THE MYENTERIC PLEXUS OF DSS COLITIS MOUSE COLON CAUSES THE COLONIC DYSMOTILITY IN THE COLITIS2023
- Author(s)
  Kana Miyata, Takeshi Yamamoto, Shusaku Hayashi, Makoto Kadowaki
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] Dysmotility Associated by Colonic Inflammation Is Attributed to Preferential Neurogenesis of Nitrergic Neurons in the Myenteric Plexus of DSS Colitis Mouse Colon2023
- Author(s)
  Kana Miyata, Takeshi Yamamoto, Shusaku Hayashi, Makoto Kadowaki
- Organizer
  Falk Symposium "Mucosal Immunology - A Translational View Into The Clinic"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] 大腸炎マウスの腸管運動不全は腸管神経系でのNO 神経の過剰な神経新生に起因する2023
- Author(s)
  門脇　真
- Organizer
  日本神経消化器病学会
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] Neurogenesis and neurodegeneration in enteric neurons of DSS colitis mouse colon2022
- Author(s)
  Makoto Kadowaki
- Organizer
  Cell Symposia: The Neuro-Immune Axis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] 腸内細菌叢は成熟マウスの腸管神経回路の形成維持に恒常的に寄与する2020
- Author(s)
  加藤諒, 緒方華子, 山本武, 門脇真
- Organizer
  富山薬学研究会2020
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] 葛根湯併用経口免疫療法による食物アレルギー疾患の寛解維持誘導について病態マウスを用いた検討2020
- Author(s)
  山本武, 宋夢, 後藤由佳, 門脇真
- Organizer
  第37回和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] 数理科学・情報科学・生命科学の融合による未病創薬への展開2020
- Author(s)
  門脇真
- Organizer
  生命医薬情報学連合大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] 漢方薬リポジショニングを目指した薬理学的および情報科学的研究2020
- Author(s)
  門脇真
- Organizer
  第37回和漢医薬学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] 腸管マクロファージでのIL-10産生を亢進させるベルベリンは炎症性腸疾患モデルにおける再燃を抑制する2020
- Author(s)
  小川雄大, 林周作, 山本武, 門脇真
- Organizer
  富山薬学研究会2020
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] An evaluation of the effects of Kakkonto in combination with dietary advice in children with food allergies through a non-randomized controlled trial.2020
- Author(s)
  Kato T., Ito Y., Yamamoto T., Shimizu M., Itazawa T., Adachi Y., Kadowaki M., Adachi Y.
- Organizer
  JSA/WAO Joint Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] 食物アレルギー病態マウスを用いた葛根湯と経口免疫療法の併用療法による寛解維持効果の検討2020
- Author(s)
  山本武, 宋夢, 後藤由佳, 門脇真
- Organizer
  JSA/WAO Joint Congress
- Data Source
  KAKENHI-PROJECT-20K07098
[Presentation] Therapeutic effects of inhibitors of the migration of plasmacytoid dendritic cells, but not conventional dendritic cells in a murine colitis model.2018
- Author(s)
  Zhang Y., Yamamoto T., Kadowaki M.
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] Enhancer of IL-10 production in intestinal macrophages ameliorates an experimental colitis in mice.2018
- Author(s)
  Hayashi S., Wakabayashi N., Ogawa Y., Hertati A., Kadowaki M.
- Organizer
  10th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] Berberine Chloride, an Enhancer of IL-10 Production in Macrophages, Suppresses the Development of an Experimental Colitis in Mice.2018
- Author(s)
  Hayashi S., Wakabayashi N., Kadowaki M.
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] 未病研究の最前線経験知の「未病」を数理科学を用いて科学知へと導く2017
- Author(s)
  門脇真
- Organizer
  日本臨床薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] インシリコスクリーニングを応用した炎症性腸疾患に対する新規治療薬の探索研究.2017
- Author(s)
  窪野孝貴, 林周作, 福西快文, 門脇真
- Organizer
  次世代を担う創薬・医療薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] Compuational analysis of the mode-of-action and pharmacological effects of Japanese Kampo medicines2017
- Author(s)
  Sawada, R., Iwata, M., Umezaki, M., Usui, Y., Kubono, T., Kadowaki, M., and Yamanishi, Y.
- Organizer
  The Sixteenth Asia Pacific Bioinformatics Conference (APBC2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] KampoDB: An integrated platform for mode-of-action analysis and repositioning of natural medicines2017
- Author(s)
  Sawada, R., Iwata, M., Umezaki, M., Usui, Y., Kubono, T., Kadowaki, M., and Yamanishi, Y.
- Organizer
  情報計算化学生物学会2017年大会
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] Enhancer of IL-10 Production in Intestinal Macrophages Suppresses the Development of an Experimental Colitis in Mice.2017
- Author(s)
  Wakabayashi N., Hayashi S., Kadowaki M.
- Organizer
  18th International Congress of Mucosal Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15408
[Presentation] Search for an Enhancer of IL-10 Production in the Intestinal Macrophages for New Therapy against Inflammatory Bowel Disease.2017
- Author(s)
  Wakabayashi N., Hayashi S., Kadowaki M.
- Organizer
  Annual Meeting of the International Cytokine & Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] Improvement of Therapeutic Efficacy of Oral Immunotherapy in Combination with Regulatory T Cell-inducer Kakkonto in a Murine Food Allergy Model.2017
- Author(s)
  Kadowaki M., Nagata Y., Hayashi M., Hayashi S., Yamamoto T
- Organizer
  East-West Integrative Medicine for Immunology & Wellness
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] CD206 Positive Intestinal Macrophages Contribute to the Colonic Epithelial Wound Healing.2017
- Author(s)
  Hayashi S., Sendo M., Hertati A., Tobe K., Kadowaki M.
- Organizer
  5th Annual Meeting of the International Cytokine & Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15408
[Presentation] CD206 Positive Intestinal Macrophages Accelerate the Colonic Epithelial Wound Healing.2017
- Author(s)
  Hayashi S., Zinsou D., Tobe K., Kadowaki M.
- Organizer
  18th International Congress of Mucosal Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15408
[Presentation] Intestinal Regulatory T Cells Induced by Kakkonto, a Traditional Japanese Herbal Medicine, Improve Therapeutic Efficacy of Oral Immunotherapy in Food Allergy Model Mice.2017
- Author(s)
  Yamamoto T., Nagata Y., Hayashi M., Kadowaki M
- Organizer
  International Congress of Mucosal Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] Search for an Enhancer of IL-10 Production in the Intestinal Macrophages for New Therapy against Inflammatory Bowel Disease.2017
- Author(s)
  Wakabayashi N., Hayashi S., Kadowaki M.
- Organizer
  5th Annual Meeting of the International Cytokine & Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15408
[Presentation] Exploration for Natural Medicines that Stimulate the Production of IL-10 in Macrophages as a Therapeutic Approach in Inflammatory Bowel Disease.2017
- Author(s)
  Zinsou D., Hayashi S., Kadowaki M.
- Organizer
  International Symposium on Scientific Research of Traditional Medicine.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15408
[Presentation] インシリコスクリーニングを用いた炎症性腸疾患に対する新規治療薬の探索.2016
- Author(s)
  窪野孝貴, 林周作, 梅嵜雅人, 門脇真
- Organizer
  日本薬学会北陸支部第128回例会
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] 漢方薬成分のインシリコ標的タンパク質探索による漢方薬リポジショニング2016
- Author(s)
  門脇真
- Organizer
  フォーラム富山「創薬」第43回研究会「情報科学・計算科学・数理科学から創薬への新展開～ウェット研究とドライ研究のコラボレーション～」
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] Generation of Technologies of Big Data Analysis to Effectively Utilize Kampo Medicines in Medical Practice.2016
- Author(s)
  Kadowaki M.
- Organizer
  6th International Symposium in Phytochemicals-Bioactivities and Diseases Prevention of Phytochemicals and Natural Products for Health
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] 食物アレルギー病態モデルにおける葛根湯の有効性とその免疫学的作用機序2013
- Author(s)
  門脇真
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24406005
[Presentation] 伝統医薬データーベースの構築（３）2013
- Author(s)
  柴原直利，条美智子，小松かつ子，Zhu Shu，門脇真，山本武，東田千尋，紺野勝弘，数馬恒平
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24590879
[Presentation] Pathophysiological role of CGRP-expressing intrinsic primary afferent neurons in a murine model of food allergy．2013
- Author(s)
  Lee J., Kim J., Zaidi SF., Kadowaki M.
- Organizer
  8th Congress of International Society for Autonomic Neuroscience
- Place of Presentation
  Giessen, Germany
- Data Source
  KAKENHI-PROJECT-24590879
[Presentation] Activation of the Cholinergic Anti-Inflammatory Pathway Through Alpha-7 Nicotinic Acetylcholine Receptors Improves Symptoms in Murine Oxazolone-Induced Ulcerative Colitis by Inhibiting Migration of Plasmacytoid Dendritic Cells.2013
- Author(s)
  Yamamoto T., Matsunami E., Kanauchi Y., Kadowaki M.
- Organizer
  Digestive Disease Week
- Place of Presentation
  Orlando, U.S.A.
- Data Source
  KAKENHI-PROJECT-24590879
[Presentation] Nicotine Suppresses Colonic Tumorigenesis Associated With Chronic Colitis in Mice Through the Inhibition of IL-6 and TNF-α Expression.2013
- Author(s)
  Hayashi S., Hamada T., Kadowaki M.
- Organizer
  Digestive Disease Week
- Place of Presentation
  Orlando, U.S.A.
- Data Source
  KAKENHI-PROJECT-24590879
[Presentation] 食物アレルギー病態モデルにおける葛根湯の有効性とその免疫学的作用機序2013
- Author(s)
  門脇真
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24590879
[Presentation] Induction of Foxp3+CD4+ Regulatory T Cells as a Novel Mechanism Underlying the Therapeutic Action of Kakkonto, a Traditional Japanese Herbal Medicine, in a Murine Food Allergy Model．2013
- Author(s)
  Yamamoto T., Kadowaki M.
- Organizer
  16th International Congress of Mucosal Immunology
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-24590879
[Presentation] 腸管免疫性疾患に対する和漢薬からのアプローチ2012
- Author(s)
  門脇真
- Organizer
  第15回天然薬物研究方法論アカデミー
- Place of Presentation
  クロス・ウェーブ船橋(千葉)(招待講演)
- Data Source
  KAKENHI-PROJECT-24406005
[Presentation] 紫雲膏の主要活性成分シコニンの核内オーファン受容体NR4Aの遺伝子発現抑制を介したマスト細胞に対する作用2012
- Author(s)
  王暁宇,林周作,山本武,門脇真
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  北里大学薬学部(東京)
- Data Source
  KAKENHI-PROJECT-24406005
[Presentation] 葛根湯の粘膜免疫系での制御性T細胞誘導による食物アレルギー抑制作用2012
- Author(s)
  門脇真
- Organizer
  第16回日本統合医療学会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-24590879
[Presentation] α7 ニコチン受容体による JAK2 –カスパーゼの活性化を介した形質細胞様樹状細胞遊走抑制作用.2012
- Author(s)
  山本武，金内優也，林周作，門脇真
- Organizer
  第14回日本神経消化器病学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590879
[Presentation] 腸管免疫性疾患に対する和漢薬からのアプローチ.2012
- Author(s)
  門脇真
- Organizer
  第15回天然薬物研究方法論アカデミー
- Place of Presentation
  千葉
- Invited
- Data Source
  KAKENHI-PROJECT-24590879
[Presentation] 樹状細胞を介した葛根湯によるエフェクターT細胞の分化・増殖の抑制2011
- Author(s)
  山本武,原優加,門脇真
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] Traditional Chinese-Japanese medicine research in mucosal immunity.2010
- Author(s)
  Kadowaki M.
- Organizer
  East-West Scientific Symposia on Allergy & Traditional Oriental Medicine
- Place of Presentation
  Luoyang, China
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] Traditional Chinese-Japanese medicine research in mucosal immunity2010
- Author(s)
  Kadowaki M
- Organizer
  East-West Scientific Symposia on Allergy & Traditional Oriental Medicine
- Place of Presentation
  Luoyang, China
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] 食物アレルギー病態モデルにおける葛根湯の新規制御性T細胞を介した腸管粘膜免疫抑制作用2010
- Author(s)
  山本武,藤原加苗,坪田悠真,門脇真
- Organizer
  第27回和漢医薬学会学術大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] Effect of kakkonto, a traditional Japanese herbal medicine, on the differentiation of CD4+T cells in the colon of food allergy model mouse2009
- Author(s)
  Yamamoto T., Fujiwara K., Yoshida M., Kadowaki M
- Organizer
  International Congress of Mucosal Immunology
- Place of Presentation
  Boston, U. S. A.
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] Effect of kakkonto, a traditional Japanese herbal medicine, on the differentiation of CD4+T cells in the colon of food allergy model mouse2009
- Author(s)
  門脇真
- Organizer
  国際粘膜免疫学会
- Place of Presentation
  ボストンアメリカ合衆国
- Year and Date
  2009-07-07
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] 食物アレルギー性消化器症状誘発病態モデルにおける葛根湯による制御性T細胞への分化亢進を介する腸管粘膜免疫系の制御機構(プレナリーセッション講演)2009
- Author(s)
  山本武,藤原加苗,氣賀澤愛,吉田益奈子,門脇真
- Organizer
  第26回和漢医薬学会学術大会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] Pathophysiological Role of Vagal Anti-inflammatory Pathway via α7-Nicotinic Receptors in Experimental Ulcerative Colitis.2007
- Author(s)
  Kadowaki M.
- Organizer
  5th Congress of the International Society for Autonomic Neuroscience.
- Place of Presentation
  Kyoto
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] Chohnergic anti-inflammatory pathway through α7-nicotinic acetylcholinle receptors in the colon reduces oxazolone-induced colitis in mouse2007
- Author(s)
  Kadowaki M.
- Organizer
  Falk workshop "Mechaisms of Intestinal lnflammation"
- Place of Presentation
  Dresden, Germany
- Year and Date
  2007-10-09
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] Pathophysiological Role of Vagal Anti-inflammatory Pathway via α7-Nicotinic Receptors in Experimental Ulcerative Colitis2007
- Author(s)
  Kadowaki, M
- Organizer
  5th Congress of the International Society for Autonomic Neuroscience
- Place of Presentation
  Kyoto
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] Cholinergic anti-inflammatory pathway through α7-nicotinic acetylcholine receptors in the colon reduces oxazolone-induced colitis in mouse.2007
- Author(s)
  Kadowaki M.
- Organizer
  Falk Workshop"Mechanisms of Intestinal Inflammation"
- Place of Presentation
  Dresden, Germany.
- Year and Date
  2007-10-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] Pathophysiological Role of Vagal Anti-inflammatory Pathway via α7-Nicotinic Receptors in Experimental Ulcerative Colitis.2007
- Author(s)
  Kadowaki M.
- Organizer
  5th Congress of the International Society for Autonomic Neuroscience.
- Place of Presentation
  京都
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] Cholinergic anti-inflammatory pathway through α7-nicotinic acetylcholine receptors in the colon reduces oxazolone-induced colitis in mouse2007
- Author(s)
  Kadowaki, M
- Organizer
  Falk Workshop "Mechanisms of Intestinal Inflammation"
- Place of Presentation
  Dresden, Germany
- Year and Date
  2007-10-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] ムラサキの生化学研究，特にシコニンの抗アレルギー作用の分子作用機序の研究
- Author(s)
  門脇真
- Organizer
  第1回ムラサキに関するシンポジウム
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24406005

1. KURAMOTO Hirofumi (30153373)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. YAMAMOTO Takeshi (70316181)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
3. KAGEYAMA Natsuko (90342865)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TOHDA Chihiro (10272931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKAKI Miyako (00033358)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KOMATSU Katsuko (50225570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ZHU Shu (20377360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAZUMA Kohei (70552446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. FUKUI Hiroshi (80145838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUGIYAMA Toshito (00196768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KADOWAKI Takashi (30185889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
12. 柴原直利 (10272907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 林周作 (10548217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
14. 山西芳裕 (60437267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 梅嵜雅人 (80534370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 渡邉朋信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 矢原夏子

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
18. 長田夕佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 富永真琴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 朱しゅう

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kadowaki Makoto 門脇 真

Kadowaki Makoto 門脇 真

KADOWAKI Makoto 門脇 真

Research Projects

Research Products

Co-Researchers

Novel Inflammatory Disease Treatment Based on Scientific Prediction of Mebyo by Integrating Kampo Medice and Mathematical InformaticsPrincipal Investigator

Principal Investigator

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Daikenchuto, a traditional Japanese Kampo medicine, suppresses colonic tumorigenesis associated with chronic colitis in micePrincipal Investigator

Principal Investigator

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Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseasesPrincipal Investigator

Principal Investigator

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Construction of a program for sustainable use of traditional medicines, based on integrated study of genetic, chemical and pharmacological diversity of medicinal plants

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Examination of the effects of constituents of traditional Japanese herbal (Kampo) medicines on the migration of plasmacytoid dendritic cells to develop a new therapeutic targetPrincipal Investigator

Principal Investigator

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Immunological tolerance induced by Kampo medicine kakkonto through the regulation of helper T cell differentiation in the mucosal immune system of the intestine.Principal Investigator

Principal Investigator

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Pathophysiological Role of Cholinergic Anti-inflammatory Pathway via Nicotinic Acetylcholine Receptors in Experimental Ulcerative ColitisPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Inhibitory reflex system by capsaicin-sensitive sensory nerves in lower esophageal sphincter

Principal Investigator

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Research Institution

Studies on colonic autonomic rhythmicity and its pacemaker mechanism in pathological model animals

Principal Investigator

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Research Institution

Food allergy and immunologic disease in the intestine : the role of primary afferent neurons in the intestinePrincipal Investigator

Principal Investigator

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Research Institution

[Journal Article] Application of the Dynamical Network Biomarker Theory to Raman Spectra2022

Author(s)

Journal Title

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[Journal Article] Neuro-immune crosstalk and food allergy: Focus on enteric neurons and mucosal mast cells2022

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Journal Title

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Data Source

[Journal Article] Cholinergic anti-inflammatory pathway ameliorates murine experimental Th2-type colitis by suppressing the migration of plasmacytoid dendritic cells2022

Author(s)

kadowaki Makoto 門脇真

Kadowaki Makoto 門脇真

KADOWAKI Makoto 門脇真