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Nakada Takaaki  中田 孝明

… Alternative Names

NAKADA Takaaki  中田 孝明

中田 孝明  ナカダ タカアキ

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Researcher Number 20375794
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-8698-8712
Affiliation (Current) 2025: 千葉大学, 大学院医学研究院, 教授
Affiliation (based on the past Project Information) *help 2018 – 2025: 千葉大学, 大学院医学研究院, 教授
2017 – 2018: 千葉大学, 大学院医学研究院, 講師
2015 – 2017: 千葉大学, 医学部附属病院, 講師
2014: 千葉大学, 大学院医学研究院, 特任講師
2013 – 2014: 千葉大学, 医学(系)研究科(研究院), 特任講師
2012: 千葉大学, 医学部附属病院, 助教
2005: 山梨大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Emergency medicine / Basic Section 55060:Emergency medicine-related
Except Principal Investigator
Basic Section 55060:Emergency medicine-related / Emergency medicine / Basic Section 62020:Web informatics and service informatics-related / Medical sociology
Keywords
Principal Investigator
遺伝子多型 / 敗血症 / 敗血症性ショック / 個別化医療 / 集中治療 / 救急 / 侵襲 / 網羅解析 / ゲノム / GWAS … More / 診断法 / Proteomics / 盲腸穿孔モデル / 急性腸間膜虚血モデル / 早期診断 / biomarker / cell free DNA / 急性腸間膜虚血 / exon / EXON / single nucleotide polymorphisms / SNPs / IL-24 / IL-20 / IL-19 / IL-10 / 血管透過性亢進 / 血管透過性 / vascular permeability / polymorphisms / Septic shock / ゲノムワイド関連解析 / 生体反応 / 外傷 / 集中治療医学 / 救急医学 / 遺伝学 / 医学 … More
Except Principal Investigator
敗血症 / 血管透過性 / SVEP1 / 遺伝子多型 / 腸管透過性 / ショック / Capillary Refilling Time / 重症急性膵炎 / polydom / 凝固障害 / Cytokine / Sepsis / 播種性血管内凝固 / 重症感染症 / 血中濃度 / TDM / 脳症 / セフェピム / STAT3 / IL-22 / 腸管免疫 / 腸内細菌叢 / Prediction / Blood Glucose / Non-contact Method / Machine Learning / Glucose / Blood Pressure / Non-contact Sensing / claudin2 / タイトジャンクション / 盲腸結紮穿孔モデル / dysbiosis / オートファジー / 救急診療 / 毛細血管再充満時間 / エクソソーム / シングルセル解析 / 間葉系幹細胞 / リンパ管 / PICS-F / 測定条件の標準化 / 高精度 / ショックの早期発見 / CRT測定 / 多数傷病者 / トリアージ / 末梢循環不全 / 集中治療 / セルレイン / CD69-Myl9/12 / 血管内皮 / 血管内皮細胞 / リンパ管内皮細胞 / リンパ管新生 / CD69 / ARDS / Covid-19 / Myl9 / DIC / 肺血症 / 腸管虚血 / proteomics / Biomarker / biomarker / 急性腸間膜虚血 / Serum paraoxonase-1 / ApolipoproteinB-100 / Proteomics / Cell-free DNA / Nonelderly / Elderly / Comprehensive analysis / 高齢 / バイオマーカー / サイトカイン / Lipopolysaccharide / PCSK9 / VLDLR / 内臓脂肪 / 皮下脂肪 / Apo A2 / HDL / 病原体脂質 / 褐色脂肪細胞 / 白色脂肪細胞 / トランスレーショナルリサーチ / オミックス解析 / 蘇生後脳症 / 心停止 / ECPR / MET / 病棟急変 / HRV / RRS / 院内急変 / モニタリング / 急変予測 / 全ゲノム配列決定 / PacBioRSⅡ / 敗血症ショック / long read型シーケンサ― / 全ゲノム解析 / 全ゲノムシーケンス / データベ―ス / 変異 / PacBioRSⅡ/Sequel / 全ゲノム / 病原性微生物 / 自動生体情報収集システム / 情報通信技術 / 救急医学 / 救急医療情報システム / 画像伝送 / ICT / 情報共有 / 受け入れ拒否 / 生体情報自動収集装置 / 救急医療システム Less
  • Research Projects

    (29 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (39 People)
  •  敗血症におけるIL-22関連蛋白を介した腸管恒常性破綻の病態解明と治療への展開

    • Principal Investigator
      近藤 乾伍
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  重症患者におけるセフェピムの薬物動態解明とTDMの必要性評価

    • Principal Investigator
      服部 憲幸
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  集中治療室に入室した患者家族の精神障害(PICS-F)の病態解明と予防バンドルの開発

    • Principal Investigator
      白崎 加純
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      St. Luke's International University
  •  敗血症における細胞外マトリックス蛋白質SVEP1の遺伝子改変動物を用いた機能解明

    • Principal Investigator
      栗田 健郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  シングルセル遺伝子発現とエクソソームに着目した間葉系幹細胞の敗血症治療への応用

    • Principal Investigator
      宮内 清司
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  定量的CRT値と臨床的有用性の確立および高精度CRT測定装置の開発

    • Principal Investigator
      三輪 弥生
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  Comprehensive analysis of multiple cytokines for the prognosis of nonelderly and elderly patients with sepsis

    • Principal Investigator
      島居 傑
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  オートファジーを介した腸管恒常性の制御による敗血症治療への応用

    • Principal Investigator
      大網 毅彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  敗血症の遺伝的素因の詳細解析と検証基盤構築Principal Investigator

    • Principal Investigator
      中田 孝明
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  重症急性膵炎におけるclaudin2の機能解析と腸管透過性の制御による治療への応用

    • Principal Investigator
      石田 茂誠
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  Machine Learning Enabled Non-contact Sensing Platform for Blood Pressure and Glucose Prediction

    • Principal Investigator
      劉 江
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 62020:Web informatics and service informatics-related
    • Research Institution
      Waseda University
  •  重症急性膵炎におけるCD 69-Myl9/12システムの関与について

    • Principal Investigator
      大村 拓
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  CRT測定条件の標準化と臨床的有用性の確立および高精度CRT測定装置の開発

    • Principal Investigator
      齋藤 大輝
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  Validation of apolipoproteinB-100,serum paraoxonase-1,cell-free DNA as a biomarker for mesenteric ischemia

    • Principal Investigator
      Karasawa Satoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  Involvement of the CD69-Myl9/12 system in septic DIC

    • Principal Investigator
      Miyaychi seiji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  Elucidation of the function of extracellular matrix proteins in sepsis

    • Principal Investigator
      Kurita Takeo
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  ECPR症例における神経学的予後予測バイオマーカーの網羅的探索

    • Principal Investigator
      安部 隆三
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Oita University
      Chiba University
  •  Sequestration of pathogen lipid by lipoprotein receptor in adipocytes

    • Principal Investigator
      Shimada Tadanaga
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  Integrated genome-wide association study in sepsisPrincipal Investigator

    • Principal Investigator
      Nakada Taka-aki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  Elucidation of the function of SVEP1 in sepsis and development of novel treatment for sepsis

    • Principal Investigator
      Kurita Takeo
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Chiba University
  •  Early Recognition of Deterioration in Hospitalized Patients Using Heart Rate Variability Analysis

    • Principal Investigator
      Tateishi Yoshihisa
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Chiba University
  •  Whole genome sequencing of pathogenic microorganisms causing septic shock

    • Principal Investigator
      Sekine Akihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Chiba University
  •  Challenges of new biomarkers of acute mesenteric ischemiaPrincipal Investigator

    • Principal Investigator
      Nakada Taka-aki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Chiba University
  •  The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock.Principal Investigator

    • Principal Investigator
      Nakada Taka-aki
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Emergency medicine
    • Research Institution
      Chiba University
  •  次世代シーケンサーを用いたエクソーム解析による急性期DIC患者の遺伝的素因の解明

    • Principal Investigator
      松村 洋輔
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Chiba University
  •  Association of angiopoietin-1 genetic polymorphisms with altered clinical outcome in septic shockPrincipal Investigator

    • Principal Investigator
      NAKADA Taka-aki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Chiba University
  •  Development of highly-sophisticated and integrated emergency medical information communication system: HI-EMICS project

    • Principal Investigator
      SHIGETO Oda
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical sociology
    • Research Institution
      Chiba University
  •  Genetic polymorphisms in severe sepsisPrincipal Investigator

    • Principal Investigator
      TAKAAKI Nakada
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Emergency medicine
    • Research Institution
      Chiba University
  •  外傷による生体反応に対する遺伝子分析に基づく個別化対策に関する研究Principal Investigator

    • Principal Investigator
      SHIGETO Oda, 中田 孝明
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Chiba University
      University of Yamanashi

All 2024 2021 2017 2015 2013 2012 2005 Other

All Journal Article Presentation Book

  • [Book] 敗血症の診断/治療の実状と 病態・メカニズムをふまえた開発戦略 - 治療薬、診断薬・試薬、医療機器・装置 -2013

    • Author(s)
      中田孝明,松岡哲也
    • Total Pages
      623
    • Publisher
      技術情報協会
    • Data Source
      KAKENHI-PROJECT-25670758
  • [Book] Annual Review 呼吸器2013, 「敗血症性ショックにおける遺伝子多型」2013

    • Author(s)
      中田孝明, 織田成人
    • Total Pages
      292
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-24689066
  • [Journal Article] VPS13D gene variant is associated with altered IL-6 production and mortality in septic shock.2015

    • Author(s)
      Nakada TA, Boyd JH, Russell JA, Aguirre-Hernández R, Wilkinson MD, Thair SA, Nakada E, McConechy MK, Fjell CD, Walley KR.
    • Journal Title

      J Innate Immun.

      Volume: 7 Issue: 5 Pages: 545-543

    • DOI

      10.1159/000381265

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02568, KAKENHI-PROJECT-25670758
  • [Journal Article] Identification of a non-synonymous polymorphism in the SVEP1 gene associated with altered clinical outcomes in septic shock.2015

    • Author(s)
      Nakada TA, Russell JA, Boyd JH, Thair SA, Walley KR.
    • Journal Title

      Crit Care Med.

      Volume: 43 Issue: 1 Pages: 101-108

    • DOI

      10.1097/ccm.0000000000000604

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02568, KAKENHI-PROJECT-25670758
  • [Journal Article] 敗血症の転帰に影響を与える遺伝子多型2013

    • Author(s)
      島田忠長, 中田孝明, 織田成人
    • Journal Title

      日本救急医学会雑誌

      Volume: 24 Pages: 1-11

    • NAID

      130004840941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24689066
  • [Journal Article] 敗血症の転帰に影響を与える遺伝子多型2013

    • Author(s)
      島田忠長, 中田孝明, 織田成人
    • Journal Title

      日本救急医学会雑誌

      Volume: 24 Pages: 1-11

    • NAID

      130004840941

    • Data Source
      KAKENHI-PROJECT-25670758
  • [Journal Article] 敗血症の初期治療の指針 -重症敗血症と敗血症性ショック-2013

    • Author(s)
      中田孝明,織田成人
    • Journal Title

      感染と抗菌薬

      Volume: 16 Pages: 22-25

    • Data Source
      KAKENHI-PROJECT-25670758
  • [Journal Article] Cytokine-related genotypic differences in peak interleukin-6 blood levels of patients with SIRS and septic complications2005

    • Author(s)
      Watanabe E, Hirasawa H, Oda S, Shiga H, Matsuda K, Nakamura M, Abe R, Nakada T.
    • Journal Title

      Journal of Trauma 59・5

      Pages: 1181-1189

    • Data Source
      KAKENHI-PROJECT-17659567
  • [Journal Article] Cytokine-related genotypic differences in peak interleukin-6 blood levels of patients with SIRS and septic complications2005

    • Author(s)
      Watanabe E, Hirasawa H, Oda S, Shiga H, Matsuda K, Nakamura M, Abe R, Nakada T
    • Journal Title

      Journal of Trauma 59・5

      Pages: 1181-1189

    • Data Source
      KAKENHI-PROJECT-17659567
  • [Journal Article] Influence of toll-like receptor 4, CD14, tumor necrosis factor, and interleukine-10 gene polymorphisms on clinical outcome in Japanese critically ill patients.2005

    • Author(s)
      Nakada TA, Hirasawa H, Oda S, Shiga H, Matsuda K, Nakamura M, Watanabe E, Abe R, Hatano M, Tokuhisa T
    • Journal Title

      Journal of Surgical Research 129・2

      Pages: 322-328

    • Data Source
      KAKENHI-PROJECT-17659567
  • [Journal Article] Influence of toll-like receptor 4, CD14, tumor necrosis factor, and interleukine-10 gene polymorphisms on clinical outcome in Japanese critically ill patients.2005

    • Author(s)
      Nakada TA, Hirasawa H, Oda S, Shiga H, Matsuda K, Nakamura M, Watanabe E, Abe R, Hatano M, Tokuhisa T.
    • Journal Title

      Journal of Surgical Research 129・2

      Pages: 322-328

    • Data Source
      KAKENHI-PROJECT-17659567
  • [Presentation] Estimation of Systolic and Diastolic Blood Pressure in a non-contact method using microwaves2024

    • Author(s)
      Miyu Matsuda, Jiang Liu, Taka-aki Nakada, Shigeru Shimamoto
    • Organizer
      2024 IEEE 21st Consumer Communications and Networking Conference, CCNC 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K11341
  • [Presentation] 敗血症マウスにおけるSVEP1の動的変化2021

    • Author(s)
      栗田健郎、大網毅彦、藤村理紗、坂本明美、幡野雅彦、中田孝明
    • Organizer
      第35回日本Shock学会総会
    • Data Source
      KAKENHI-PROJECT-21K09066
  • [Presentation] Interleukin-10ファミリー遺伝子の一塩基多型と敗血症性ショック患者の転帰との関連2017

    • Author(s)
      中田孝明
    • Organizer
      日本外科学会
    • Data Source
      KAKENHI-PROJECT-15H02568
  • [Presentation] nterleukin-10ファミリー遺伝子の一塩基多型と敗血症性ショック患者の転帰2017

    • Author(s)
      中田孝明
    • Organizer
      日本外科学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2017-04-27
    • Data Source
      KAKENHI-PROJECT-15H02568
  • [Presentation] Polymorphism of Angiopoietin-1 rs4324901 is Associated with Increased Fluid Overload and Mortality of Septic Shock.2013

    • Author(s)
      Taka-aki Nakada, John H. Boyd, Keith R. Walley, James A. Russell
    • Organizer
      42nd Critical Care Congress
    • Place of Presentation
      Puerto Rico (San Juan)
    • Year and Date
      2013-01-20
    • Data Source
      KAKENHI-PROJECT-24689066
  • [Presentation] A genome-wide scan of functional SNPs identifies novel loci associated with altered clinical outcome of septic shock.2013

    • Author(s)
      Nakada TA. Shigeto Oda, Hiroyuki Hirasawa, John Boyd, Keith Walley, James Russell.
    • Organizer
      The 7th Asian Conference on Emergency Medicine
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-25670758
  • [Presentation] The impact of genetic polymorphisms on the outcome of septic shock.2013

    • Author(s)
      Nakada TA.
    • Organizer
      Australian New Zealand Intensive Care Society/ Australian College of Critical Care Nurses (ANZICS/ACCCN) Intensive Care Annual Scientific Meeting 2013
    • Place of Presentation
      Hobart, Tasmania, Australia
    • Data Source
      KAKENHI-PROJECT-25670758
  • [Presentation] ゲノムワイド関連解析による敗血症性ショックの転帰に関連する新規遺伝子多型の探索2013

    • Author(s)
      中田孝明,織田成人,平澤博之
    • Organizer
      第41回日本救急医学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25670758
  • [Presentation] 敗血症性ショックとangiopoietin-1遺伝子多型2013

    • Author(s)
      中田孝明,織田成人,平澤博之,Keith Walley,James Russell
    • Organizer
      第113回日本外科学会総会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25670758
  • [Presentation] Beta2-adrenergic receptor遺伝子多型と敗血症性ショック患者の転帰2012

    • Author(s)
      中田孝明, 平澤博之, 織田成人, James Russell, Keith Walley
    • Organizer
      日本救急医学会
    • Place of Presentation
      京都
    • Year and Date
      2012-11-15
    • Data Source
      KAKENHI-PROJECT-24689066
  • [Presentation] Vacuolar protein sorting 13 homolog D (VPS13D)遺伝子多型とIL-6産生および敗血症性ショックの転帰との関連2012

    • Author(s)
      中田孝明, 平澤博之, 織田成人, James Russell, Keith Walley
    • Organizer
      日本外科学会
    • Place of Presentation
      千葉
    • Year and Date
      2012-04-12
    • Data Source
      KAKENHI-PROJECT-24689066
  • [Presentation] 高精度救急医療情報システムのための自動生体情報収集装置(耳朶・胸部バイオセンサ)の開発

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      織田成人,中田孝明,仲村将高,安部隆三,近藤針次
    • Organizer
      第11回千葉大学医工学シンポジウム
    • Place of Presentation
      千葉大学
    • Data Source
      KAKENHI-PROJECT-24659232
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