Fikazawa Kakuya 深澤拓也

… Alternative Names

FUKAZAWA Takuya 深澤拓也

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Researcher Number	20379845
Other IDs	https://orcid.org/0000-0003-2890-0599
Affiliation (Current)	2024: 川崎医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 川崎医科大学, 医学部, 准教授 2010 – 2015: 川崎医科大学, 医学部, 講師 2006 – 2009: 岡山大学, 医学部, 客員研究員
Review Section/Research Field	Principal Investigator Respiratory surgery / Basic Section 55040:Respiratory surgery-related / Basic Section 50010:Tumor biology-related / Thoracic surgery Except Principal Investigator Thoracic surgery / Basic Section 55040:Respiratory surgery-related / Digestive surgery / Basic Section 55020:Digestive surgery-related / Respiratory surgery
Keywords	Principal Investigator オルガノイド / 肺扁平上皮癌 / 肺癌 / 肺大細胞神経内分泌癌 / 肺大細胞神経内分泌 / ゲノム編集 / 扁平上皮癌 / 分子標的治療法 / Midkine / Sox2遺伝子 / アデノウイルスベクター / K-Ras / Myc … More Except Principal Investigator … More 食道癌 / 肺癌 / Surfactant protein A / オルガノイド / 肺扁平上皮癌 / HSP90阻害剤 / 分子標的治療 / 食道外科学 / AUY922 / HSP90 / Thyroid transcription factor 1 / グルココルチコイド / Thyriod transcription factor 1 / TTF1 / KRas / プロモータ / 胸膜中皮腫 / 非小細胞肺癌 / BRAF V600E / 分子標的 / BRAF / 肺腺癌 / ミッドカイン / 癌幹細胞 / 悪性胸膜中皮腫 / 分子標的治療法 / Midkaine / AKT / PIK3CA / Glucocorticoid / Lung cancer / 遺伝子治療 / Gefitinib / hTERT / 肺胞サーファクタントプロティンA / Thyroid transcription factor / 肺外科 / 人口転写因子 / Sox2 / AUY-922 / 非小細胞性肺癌 / 呼吸器外科学 / 抗腫瘍効果 / inhibitor / 11 / Midkine / Akt / ヘパラナーゼ / 核内移行 / 進行肺癌 / 肺胞サーファクタント / 制限増殖アデノウイルス / cisplatin / intratracheal administration / adenovirus / non small cell lung cancer / surfactant protein / 中皮腫 / 制限増殖型アデノウイルス / E1A / Bid / CRI1 Less

非小細胞肺癌の再発と予後に関わるゲノムの倍加、不均一性の解析
- Principal Investigator
  
  湯川拓郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kawasaki Medical School
Elucidation of the pathogenesis and development of personalized medicine for esophageal adenocarcinoma arisen from Barrett's esophagus using patient-derived organoids.
- Principal Investigator
  
  猶本良夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kawasaki Medical School
Elucidation of molecular pathogenesis and carcinogenesis in pulmonary large cell neuroendocrine carcinoma using patient derived organoidsPrincipal Investigator
- Principal Investigator
  
  深澤拓也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kawasaki Medical School
BRAF non-V600E変異陽性肺癌に対する新規治療法の開発
- Principal Investigator
  
  湯川拓郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kawasaki Medical School
Development of novel clinical compounds for treating lung squamous cell carcinoma via academic drug discovery
- Principal Investigator
  
  Naomoto Yoshio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kawasaki Medical School
Elucidation of mechanism of carcinogenesis and progression in lung squamous cell carcinoma with organoid technologyPrincipal Investigator
- Principal Investigator
  
  Fukazawa Takuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Medical School
Development of a novel therapy targeting the stemness of esophageal cancer using organoid technology
- Principal Investigator
  
  Haisa Minoru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kawasaki Medical School
Development of strategies to treat malignant mesothelioma by novel PIK3CA inhibitors
- Principal Investigator
  
  Naomoto Yoshio
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kawasaki Medical School
Identification of novel candidate compounds for the treatment of lung squamous cell carcinoma by academic drug discoveryPrincipal Investigator
- Principal Investigator
  
  Fukazawa Takuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Kawasaki Medical School
Development of artificial transcription factors for the treatment of lung and esophageal squamous cell carcinoma
- Principal Investigator
  
  Naomoto Yoshio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kawasaki Medical School
Sox2 is a novel target gene for the treatment of lung squamous cell carcinoma.Principal Investigator
- Principal Investigator
  
  Fukazawa Takuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kawasaki Medical School
Antitumor effect of a novel HSP90 inhibitor in esophageal cancer cells
- Principal Investigator
  
  YAMATSUJI Tomoki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kawasaki Medical School
Development of novel therapies targeting esophageal cancer using Midkine inhibitors
- Principal Investigator
  
  NAOMOTO YOSHIO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kawasaki Medical School
Development of novel molecular targeted therapies for the treatment of KRas mutated non small lung cancer using a HSP90 inhibitor
- Principal Investigator
  
  MORITA ICHIRO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kawasaki Medical School
Investigation of novel therapeutic alternative to gastrointestinal cancer using a HSP90 inhibitor
- Principal Investigator
  
  YAMATSUJI Tomoki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kawasaki Medical School
  Okayama University
Development of novel Myc and K-Ras targeted therapies for the treatment of lung cancerPrincipal Investigator
- Principal Investigator
  
  FUKAZAWA Takuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kawasaki Medical School
  Okayama University
Targeting advanced non small cell lung cancer in vivo by pulmonary surfactant -adenovirus-mediated gene transfer
- Principal Investigator
  
  MATSUOKA Jyunji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
第三世代制限増殖ウイルスベクターを用いた瀰漫性胸膜中皮腫に対する新規治療法の開発
- Principal Investigator
  
  TANAKA Noriaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
HUMAN NON-SMALL CELLLUNG CANCER TARGETED PROMOTER SYSTEM FOR GENE THERAPY
- Principal Investigator
  
  MATSUOKA Junji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University

[Journal Article] Clinical application of a lung cancer organoid (tumoroid) culture system2021
- Author(s)
  Yokota Etsuko、Iwai Miki、Yukawa Takuro、Yoshida Masakazu、Naomoto Yoshio、Haisa Minoru、Monobe Yasumasa、Takigawa Nagio、Guo Minzhe、Maeda Yutaka、Fukazawa Takuya、Yamatsuji Tomoki
- Journal Title
  
  npj Precision Oncology
  
  Volume: 5 Issue: 1 Pages: 29-29
- DOI
  10.1038/s41698-021-00166-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07699, KAKENHI-PROJECT-19K09205, KAKENHI-PROJECT-20K17765, KAKENHI-PROJECT-21K08893
[Journal Article] 人工転写因子を用いた癌抑制技術開発2020
- Author(s)
  深澤拓也
- Journal Title
  
  医学のあゆみ　第５土曜特集　ゲノム編集の未来
  
  Volume: 273 Pages: 885-892
- Data Source
  KAKENHI-PROJECT-19K09205
[Journal Article] 人工転写因子を用いた癌抑制技術開発2020
- Author(s)
  深澤拓也
- Journal Title
  
  医学のあゆみ　第５土曜特集　ゲノム編集の未来
  
  Volume: 273 Pages: 885-892
- Data Source
  KAKENHI-PROJECT-19K07699
[Journal Article] SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.2016
- Author(s)
  Fukazawa T, Guo M, Ishida N, Yamatsuji T, Takaoka M, Yokota E, Haisa M, Miyake N, Ikeda T, Okui T, Takigawa N, Maeda Y, Naomoto Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 20113-20113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462188
[Journal Article] SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.2016
- Author(s)
  Fukazawa T, Guo M, Ishida N, Yamatsuji T, Takaoka M, Yokota E, Haisa M, Miyake N, Ikeda T, Okui T, Takigawa N, Maeda Y, Naomoto Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 20113-20113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462141
[Journal Article] Sasaki A. Novel HSP90 inhibitor NVP-AUY922 enhances the anti-tumor effect of temsirolimus against oral squamous cell carcinoma.2013
- Author(s)
  Okui T, Shimo T, Fukazawa T, Mohammad Monsur Hassan N, Honami T, Ibaragi S, Takaoka M, Naomoto Y
- Journal Title
  
  Current Cancer Drug Targets
  
  Volume: 13（3） Pages: 289-299
- Data Source
  KAKENHI-PROJECT-24591964
[Journal Article] Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer.2013
- Author(s)
  Bao XH, Takaoka M, Hao HF, Fukazawa T, Yamatsuji T, Sakurama K, Takigawa N, Nakajima M, Fujiwara T, Naomoto Y
- Journal Title
  
  Oncology Reports
  
  Volume: 29（1） Pages: 45-50
- Data Source
  KAKENHI-PROJECT-24591964
[Journal Article] Antiproliferative effect of a novel mTOR inhibitor temsirolimus contributes to the prolonged survival of orthotopic esophageal cancer-bearing mice.2013
- Author(s)
  Nishikawa T, Takaoka M, Ohara T, Tomono Y, Hao H, Bao X, Fukazawa T, Wang Z, Sakurama K, Fujiwara Y, Motoki T, Shirakawa Y, Yamatsuji T, Tanaka N, Fujiwara T, Naomoto Y
- Journal Title
  
  Cancer biology & therapy
  
  Volume: 14（3） Pages: 230-236
- NAID
  120005324790
- Data Source
  KAKENHI-PROJECT-24591964
[Journal Article]2013
- Author(s)
  Hao H, Maeda Y, Fukazawa T, Yamatsuji T, Takaoka M, Bao XH, Matsuoka J, Okui T, Shimo T, Takigawa N, Tomono Y, Nakajima M, Fink-Baldauf IM, Nelson S, Seibel W, Papoian R, Whitsett JA, Naomoto Y.
- Journal Title
  
  PLoS One
  
  Volume: 8(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591950
[Journal Article] Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer.2013
- Author(s)
  Hao H, Maeda Y, Fukazawa T, Yamatsuji T, Takaoka M, Bao XH, Matsuoka J, Okui T, Shimo T, Takigawa N, Tomono Y, Nakajima M, Fink-Baldauf IM, Nelson S, Seibel W, Papoian R, Whitsett JA, Naomoto Y.
- Journal Title
  
  PLoS One.
  
  Volume: 16 Issue: 8 Pages: 8-8
- DOI
  10.1371/journal.pone.0071093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591950
[Journal Article] Antiproliferative effect of HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer2012
- Author(s)
  Xiao-hong Bao, Munenori Takaoka, Hui-fang Hao1, Takuya Fukazawa, Tomoki Yamatsuji, Kazufumi Sakurama1, Nagio Takigawa, Motowo Nakajima, Toshiyoshi Fujiwara, Yoshio Naomoto
- Journal Title
  
  Oncology Report
  
  Volume: (in press掲載決定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591700
[Journal Article] Antiproliferative effect of the HSP90 inhibitor　NVP-AUY922 is determined by the　expression of PTEN in esophageal cancer2012
- Author(s)
  Bao XH, Fukazawa T, Yamatsuji T, Naomoto Y.et al.
- Journal Title
  
  Oncology Report
  
  Volume: 29 Issue: 1 Pages: 45-50
- DOI
  10.3892/or.2012.2074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591964
[Journal Article] Antitumor effect of novel HSP90 inhibitor NVP-AUY922 against oral squamous cell carcinoma2011
- Author(s)
  Okui T, Shimo T, Hassan NM, Fukazawa T, Kurio N, Takaoka M, Naomoto Y, Sasaki
- Journal Title
  
  Anticancer Res
  
  Volume: Vol31 Pages: 1197-1204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591700
[Journal Article] Antitumor Effect of Novel HSP90 Inhibitor NVP-AUY922 against Oral Squamous Cell Carcinoma2011
- Author(s)
  Okui T, Shimo T, Hassan NM, Fukazawa T, Kurio N, Takaoka M, Naomoto Y, Sasaki A.
- Journal Title
  
  Anticancer Research
  
  Volume: 31 Pages: 1197-1204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591700
[Journal Article] Targeting KRAS Mutation-bearing Lung Cancer In Vivo by Pulmonary Surfactant-Adenovirus-mediated Gene Transfer2010
- Author(s)
  Fukazawa T, et al.
- Journal Title
  
  Anticancer Research
  
  Volume: 30 Pages: 4925-4935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390369
[Journal Article] Inhibition of Myc effectively targets KRAS mutation-positive lung cancer expressing high levels of Myc.2010
- Author(s)
  Fukazawa T, Maeda Y, Matsuoka J, Yamatsuji T, Shigemitsu K, Morita I, Faiola F, Durbin ML, Soucek L, Naomoto Y.
- Journal Title
  
  Anticancer Research
  
  Volume: 30 Pages: 4193-4200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591814
[Journal Article] Targeting KRAS Mutation-bearing Lung Cancer In Vivo by Pulmonary Surfactant-Adenovirus-mediated Gene Transfer.2010
- Author(s)
  Fukazawa T, Maeda Y, Matsuoka J, Ono T, Mominoki K, Yamatsuji T, Shigemitsu K, Morita I, Murakami I, Tanaka H, Durbin ML, Naomoto Y.
- Journal Title
  
  Anticancer Research. 125
  
  Pages: 4925-4935
- Data Source
  KAKENHI-PROJECT-20390369
[Journal Article] Drug-regulatable cancer cell death induced by BID under control of the tissue-specific, lung cancer-targeted TTS promoter system.2009
- Author(s)
  Fukazawa T, Matsuoka J, Tanaka N, Tanaka H, Durbin ML Maeda Y, Naomoto Y.
- Journal Title
  
  Int J Cancer. 125
  
  Pages: 1975-1984
- Data Source
  KAKENHI-PROJECT-20390369
[Journal Article] Drug-regulatable cancer cell death induced by BID under control of the tissue-specific, lung cancer-targeted TTS promoter system2009
- Author(s)
  Fukazawa T, et al.
- Journal Title
  
  International Journal of Cancer 125
  
  Pages: 1975-1984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390369
[Journal Article] Malignant Pleural Mesothelioma-Targeted CREBBP/EP300 Inhibitory Protein 1 Promoter System for Gene Therapy and Virotherapy2008
- Author(s)
  Takuya Fukazawa, Junji Matsuoka, Yoshio Naomoto, Yutaka Maeda, Mary Durbin, Noriaki Tanaka
- Journal Title
  
  Cancer Research 68
  
  Pages: 7120-7129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659353
[Journal Article] Pulmonary adenocarcinoma, Vtargeted gene therapy by a cancer-and tissue-specific promoter system2007
- Author(s)
  Fukazawa T, et. al.
- Journal Title
  
  Mol Cancer Ther. 6
  
  Pages: 244-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591548
[Journal Article] Pulmonary adenocarcinoma targeted gene therapy by a cancer-and tissue-specific promoter system2007
- Author(s)
  Fukazawa T, et. al.
- Journal Title
  
  Mol Cancer Ther. 6
  
  Pages: 244-252
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591548
[Journal Article] Pulmonary adenocarcinoma-targeted gene therapy by a cancer- and tissue-specific promoter system2007
- Author(s)
  Fukazawa T, Maeda Y, Durbin ML, Nakai T, Matsuoka J, Tanaka H, Naomoto Y, Tanaka N.
- Journal Title
  
  Molecular and Cancer Therapeutics 6巻・1号
  
  Pages: 244-252
- Data Source
  KAKENHI-PROJECT-18591548
[Journal Article] Pulmonary adenocarcinoma-targeted gene therapy by a cancer-and tissue-specific promoter system2007
- Author(s)
  Fukazawa, T., Maeda, Y., Durbin, ML., Nakai, T., Matsuoka, J., Tanaka, H., Naomoto, Y., Tanaka, N
- Journal Title
  
  Mol Cancer Then 6
  
  Pages: 244-252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591548
[Patent] METHODS AND COMPOSITIONS TO TREAT CANCER2018
- Inventor(s)
  深澤拓也
- Industrial Property Rights Holder
  深澤拓也
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-17K10813
[Patent] METHODS AND COMPOSITIONS TO TREAT CANCER2017
- Inventor(s)
  ①深澤拓也 ②Whitsett Jeffrey A ③前田　豊
- Industrial Property Rights Holder
  ①シンシナティチルドレンズホスピタル②深澤拓也
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-17K10813
[Patent] 扁平上皮癌に対する抗腫瘍剤2017
- Inventor(s)
  猶本　良夫、深澤　拓也、世良　貴史
- Industrial Property Rights Holder
  学校法人川崎学園
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-038047
- Filing Date
  2017-03-01
- Data Source
  KAKENHI-PROJECT-26462141
[Patent] 特許 : 中皮腫特異的プロモータおよびその用途2008
- Inventor(s)
  深澤拓也松岡順治田中紀章
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2008-104070
- Filing Date
  2008-04-11
- Data Source
  KAKENHI-PROJECT-19659353
[Presentation] 肺癌オルガノイド樹立におけるFISH法を用いた核型解析の有用性2021
- Author(s)
  深澤拓也，横田悦子，岩井美樹，石田雄大, 湯川拓郎，吉田将和，羽井佐実，瀧川奈義夫, 物部泰昌，前田豊，Minzhe Guo, 山辻知樹.
- Organizer
  第62回日本肺癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09205
[Presentation] 個別化医療のための切除肺癌組織由来オルガノイドの作製肺癌.2021
- Author(s)
  深澤拓也，横田悦子，岩井美樹，湯川拓郎，羽井佐実，瀧川奈義夫，物部泰昌, 吉田将和，前田豊，Minzhe Guo, 猶本良夫.
- Organizer
  第38回日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08893
[Presentation] 肺癌オルガノイド樹立におけるFISH法を用いた核型解析の有用性2021
- Author(s)
  深澤拓也，横田悦子，岩井美樹，石田雄大, 湯川拓郎，吉田将和，羽井佐実，瀧川奈義夫, 物部泰昌，前田豊，Minzhe Guo, 山辻知樹
- Organizer
  第62回日本肺癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07699
[Presentation] 個別化医療のための切除肺癌組織由来オルガノイドの作製肺癌.2021
- Author(s)
  深澤拓也，横田悦子，岩井美樹，湯川拓郎，羽井佐実，瀧川奈義夫，物部泰昌, 吉田将和，前田豊，Minzhe Guo, 猶本良夫
- Organizer
  第38回日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07699
[Presentation] 肺癌オルガノイド培養システムの確立とその臨床応用2021
- Author(s)
  深澤拓也，横田悦子，岩井美樹，湯川拓郎，吉田将和，羽井佐実，瀧川奈義夫，猶本良夫, 前田豊，Minzhe Guo, 山辻知樹
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07699
[Presentation] 個別化医療のための切除肺癌組織由来オルガノイドの作製肺癌.2021
- Author(s)
  深澤拓也，横田悦子，岩井美樹，湯川拓郎，羽井佐実，瀧川奈義夫，物部泰昌, 吉田将和，前田豊，Minzhe Guo, 猶本良夫.
- Organizer
  第38回日本呼吸器外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09205
[Presentation] 肺癌オルガノイド培養システムの確立とその臨床応用.2021
- Author(s)
  深澤拓也，横田悦子，岩井美樹，湯川拓郎，吉田将和，羽井佐実，瀧川奈義夫，猶本良夫, 前田豊，Minzhe Guo, 山辻知樹
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09205
[Presentation] 肺癌オルガノイド培養システムの確立とその臨床応用.2021
- Author(s)
  深澤拓也，横田悦子，岩井美樹，湯川拓郎，吉田将和，羽井佐実，瀧川奈義夫，猶本良夫, 前田豊，Minzhe Guo, 山辻知樹
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08893
[Presentation] 肺癌オルガノイド樹立におけるFISH法を用いた核型解析の有用性2021
- Author(s)
  深澤拓也，横田悦子，岩井美樹，石田雄大, 湯川拓郎，吉田将和，羽井佐実，瀧川奈義夫, 物部泰昌，前田豊，Minzhe Guo, 山辻知樹
- Organizer
  第62回日本肺癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08893
[Presentation] Suppression of cancer growth by transcriptional regulation based on gene editing technology2020
- Author(s)
  Fukazawa T, Yokota E, Sakuma T, Naomoto Y, Yamamoto T, Yamatsuji T
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07699
[Presentation] Suppression of cancer growth by transcriptional regulation based on gene editing technology2020
- Author(s)
  Fukazawa T, Yokota E, Sakuma T, Naomoto Y, Yamamoto T, Yamatsuji T
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09205
[Presentation] Development of a novel targeted therapy for malignant mesothelioma by a midkine inhibitor.2017
- Author(s)
  Takuya Fukazawa, Yuitaka Maeda, Tomoki Yamatsuji, Munenori Takaoka, Masakazu Yoshida, Naomasa Ishida, Miki Iwai, Etsuko Yokota, Takuro Yukawa, Minoru Haisa, Noriko Miyake, Tomoko Ikeda, Nagio Takigawa, Jeffery Whitsett, Yoshio Naomoto
- Organizer
  AACR Annual Meeting 2017
- Place of Presentation
  Center, Cincinnati, OH,Washington DC,USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15638
[Presentation] 人工転写因子を用いた肺扁平上皮癌に対する新規標的療法の開発2015
- Author(s)
  横田悦子、深澤拓也、山辻知樹、高岡宗徳、羽井佐実、三宅規子、池田智子、石田尚正、吉田将和、瀧川奈義夫、世良貴史、猶本良夫
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-26462141
[Presentation] Esophageal cancer exhibits a resistance to the chemical inhibition of IGF-1R with a maintained Ras-MAPK activity2015
- Author(s)
  Munenori Takaoka, XiaoHong Bao, Huifang Hao, Naomasa Ishida, Takuya Fukazawa, Tomoki Yamatsuji, Minoru Haisa, Yoshio Naomoto
- Organizer
  American Association for Cancer Research　2015
- Place of Presentation
  Philadelphia, Pennsylvania,USA（Pannsylvania Convention Center)
- Year and Date
  2015-04-20
- Data Source
  KAKENHI-PROJECT-24591964
[Presentation] 人工転写因子を用いた肺扁平上皮癌に対する新規標的療法の開発2015
- Author(s)
  横田悦子1、深澤拓也1、山辻知樹1、高岡宗徳1、羽井佐実1、三宅規子2、池田智子2、石田尚正1、吉田将和1、瀧川奈義夫3、世良貴史4、猶本良夫1 (1 川崎医科大学・総合外科、2 川崎病院研究センター、3 川崎医科大学・総合内科 4、4 岡山大学・生命工学・生体機能分子設計)
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-25462188
[Presentation] Midkine阻害剤を用いた非小細胞肺癌に対する新規治療法開発.2013
- Author(s)
  深澤拓也、前田豊、山辻知樹、高岡宗徳、森田一郎、瀧川奈義夫、猶本良夫
- Organizer
  第54回日本肺癌学会総会
- Place of Presentation
  東京都千代田区
- Year and Date
  2013-11-21
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] Development of novel targeted therapies for non-small cell carcinoma by novel Midkine inhibitors2013
- Author(s)
  Takuya Fukazawa, Yutaka Maeda, Huifang Hao, Tomoki Yamatsuji, Munenori Takaoka, Nagio Takigawa, and Yoshio Naomoto
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  米国ワシントンDC
- Year and Date
  2013-04-08
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] 肺腺癌に対するMidkineを標的とした新規治療法の開発2013
- Author(s)
  深澤拓也、山辻知樹、前田豊、瀧川奈義夫、高岡宗徳、森田一郎、中島元夫、ジェフリー・ウィトセット、猶本良夫
- Organizer
  第113回日本外科学会学術集会
- Place of Presentation
  福岡県博多
- Year and Date
  2013-04-11
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] Inhibition of Midkine by a novel small molecule compound to treat non-small cell lung cancer2013
- Author(s)
  Takuya Fukazawa1, Huifang Hao1, Tomoki Yamatsuji1, Munenori Takaoka1, Nagio Takigawa2, Yutaka Maeda3, Junji Matsuoka4, Tatsuo Okui5, Tsuyoshi Shimo5, Yasuko Tomono6, Motowo Nakajima7, Jeffrey A. Whitsett2 and Yoshio Naomoto
- Organizer
  第72回日本癌学会　学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-23591950
[Presentation] HSP90阻害剤NVP-AUY922による食道癌にたいする抗腫瘍効果はPTENの発現により変化する2012
- Author(s)
  高岡宗徳、山田貴子、木下真一郎、林次郎、深澤拓也、繁光薫、山辻知樹、吉田和弘、森田一郎、猶本良夫
- Organizer
  第66回日本食道学会学術集会
- Place of Presentation
  長野県軽井沢
- Year and Date
  2012-06-22
- Data Source
  KAKENHI-PROJECT-21591700
[Presentation] HSP90 inhibitor NVP-AUY922 exhibits the potent antiproliferative effect in gastrointestinal cancer cells with a lack of PTEN expression2012
- Author(s)
  Munenori Takaoka, Xiaohong Bao, Huifang Hao, Takuya Fukazawa, Tomoki Yamatsuji, Yasuko Tomono, Kazufumi Sakurama and Yoshio Naomoto
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  米国シカゴ
- Year and Date
  2012-04-02
- Data Source
  KAKENHI-PROJECT-21591700
[Presentation] K-ras及びMycを標的とした新規非小細胞肺癌治療法の開発2011
- Author(s)
  深澤拓也,森田一郎,木下真一郎,吉田和弘,山辻知樹,繁光薫,林次郎,松岡順次,前田豊, Durbin Mary, Soucek Laura,猶本良夫
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-23592078
[Presentation] K-Ras及びMycを標的とした肺癌治療法の開発のための基礎的検討2011
- Author(s)
  深澤拓也
- Organizer
  第64回日本胸部外科学会学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-21591814
[Presentation] 消化器悪性腫瘍に対する新規治療戦略としてのheat-shock protein 90阻害剤の可能性2011
- Author(s)
  高岡宗徳、Hao Huifang、Bao Xiaohong、山辻知樹、深澤拓也、友野靖子、木下真一郎、林次郎、繁光薫、吉田和弘、森田一郎、猶本良夫
- Organizer
  第66回消化器外科学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591700
[Presentation] K-Ras及びMycを標的とした新規非小細胞肺癌治療法の開発2011
- Author(s)
  深澤拓也
- Organizer
  第52回日本肺癌学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21591814
[Presentation] Inhibition of Myc Effedtively Targets KRAS Mutation-positive Lung Cancer2011
- Author(s)
  深澤拓也,山辻知樹,繁光薫,高岡宗徳,木下真一郎,森田一郎,前田豊, Mary Durbin, Soucek Laura,猶本良夫
- Organizer
  第64回日本胸部外科学会定期学術集会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-23592078
[Presentation] Adenoviral mediated expression of Omomyc induced growth inhibition and apoptosis in lung cancer expressing Myc2010
- Author(s)
  Fukazawa T, Matsuoka J, Yamatsuji T, Faiola F, Durbin ML, Naomoto Y
- Organizer
  米国癌学会年次総会
- Place of Presentation
  Washington DC
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-21591814
[Presentation] 肺胞サーファクタントを用いたKRAS変異肺癌を標的とする新規ウイルス療法の開発2010
- Author(s)
  深澤拓也
- Organizer
  日本癌学会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20390369
[Presentation]2010
- Author(s)
  深澤拓也
- Organizer
  岡山癌免疫研究会
- Place of Presentation
  岡山
- Year and Date
  2010-06-22
- Data Source
  KAKENHI-PROJECT-20390369
[Presentation] Adenoviral mediated expression of Omomyc induced growth inhibition and apoptosis in lung cancer expressing Myc2010
- Author(s)
  深澤拓也
- Organizer
  第101回米国癌学会年次総会
- Place of Presentation
  Washington DC
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-21591814
[Presentation] Malignant Pleural Mesothelioma-Targeted CREBBP/EP300 Inhibitory Protein 1 Promoter System for Gene Therapy and Virotherapy2008
- Author(s)
  Takuya Fukazawa, Junji Matsuoka, Yoshio Naomoto, Yutaka Maeda, Nakai Torn, Inoue Fumiyuki, Takahashi Masahiko, Mary Durbin, Noriaki Tanaka
- Organizer
  日本癌学会第67回学術総会(English Workshop)
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19659353
[Presentation] 胸膜中皮腫遺伝子治療のための特異的目的遺伝子発現システムの開発2008
- Author(s)
  深澤拓也, 松岡順治以下 7名
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19659353
[Presentation] Malignant pleural mesothelioma-targeted gene therapy2007
- Author(s)
  深澤拓也, 松岡順治以下 8名
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19659353
[Presentation] Identification of a novel promoter for the induction of genes into malignant pleural mesothelioma2007
- Author(s)
  深澤拓也, 松岡順治以下 5名
- Organizer
  98th Annual Meeting American Association for Cancer Research
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-19659353
[Presentation] HUMAN NON-SMALL CELL LUNG CANCER TARGETED PROMOTER SYSTEM FOR GENE THERAPY2006
- Author(s)
  Fukazawa, T., Matsuoka, J., Naomoto, Y., Nakai, T., Maeda, Y., Frances, M., Sladek, Laurie, B., Owen-Schaub, Jeffrey, Whitsett, Tanaka, N
- Organizer
  65th Annual Meeting of Japanese Association for Cancer Research
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591548
[Presentation] 組織かつ癌特異的目的遺伝子発現システムによる肺腺癌治療への応用2006
- Author(s)
  深澤拓也, 松岡順治以下8名
- Organizer
  第65回日本癌学会総会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591548
[Presentation] HSP90阻害剤NVP-AUY922による食道癌にたいする抗腫瘍効果はPTENの発現により変化する
- Author(s)
  高岡宗徳、深澤拓也、山辻知樹、猶本良夫ほか
- Organizer
  第66回日本食道学会学術集会
- Place of Presentation
  長野県軽井沢
- Data Source
  KAKENHI-PROJECT-24591964
[Presentation] HSP90 inhibitor NVP-AUY922 exhibits the potent antiproliferative effect in gastrointestinal cancer cells with a lack of PTEN expression.
- Author(s)
  Takaoka M, Fukazawa T, Yamatsuji T, Naomoto Y.et al.
- Organizer
  AACR Annual Meeting 2012.
- Place of Presentation
  米国シカゴ
- Data Source
  KAKENHI-PROJECT-24591964

1. NAOMOTO Yoshio (00237190)

# of Collaborated Projects: 14 results

# of Collaborated Products: 37 results
2. YAMATSUJI Tomoki (40379730)

# of Collaborated Projects: 14 results

# of Collaborated Products: 31 results
3. TAKAOKA Munenori (50548568)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
4. MATSUOKA Jyunji (30332795)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
5. TANAKA Noriaki (10127566)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
6. Haisa Minoru (70322229)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
7. 湯川拓郎 (80388975)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
8. TANAKA Hirotosh (00171794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
9. 繁光薫 (50585007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. ONO Toshiro (50185641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. MOMINOKI Katsumi (70304615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUTYA Tomoshi (30437884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAKAJIMA Motowo (90240738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. MORITA ICHIRO (30200413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 世良貴史 (10362443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 吉田将和 (30868914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 近藤英作 (30252951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 瀧川奈義夫 (60325107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 佐久間哲史 (90711143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 樅木勝巳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fikazawa Kakuya 深澤 拓也

FUKAZAWA Takuya 深澤 拓也

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Elucidation of molecular pathogenesis and carcinogenesis in pulmonary large cell neuroendocrine carcinoma using patient derived organoidsPrincipal Investigator

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Elucidation of mechanism of carcinogenesis and progression in lung squamous cell carcinoma with organoid technologyPrincipal Investigator

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Identification of novel candidate compounds for the treatment of lung squamous cell carcinoma by academic drug discoveryPrincipal Investigator

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Sox2 is a novel target gene for the treatment of lung squamous cell carcinoma.Principal Investigator

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Fikazawa Kakuya 深澤拓也

FUKAZAWA Takuya 深澤拓也