Kabe Yasuaki 加部泰明

… Alternative Names

KABE Yasuaki 加部泰明

KABE Yasuaka 加部泰明

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Researcher Number	20397037
Other IDs
Affiliation (Current)	2025: 高知大学, 教育研究部医療学系基礎医学部門, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 慶應義塾大学, 医学部(信濃町), 准教授 2016 – 2018: 慶應義塾大学, 医学部(信濃町), 講師 2015: 慶應義塾大学, 医学部, 講師 2011 – 2013: 慶應義塾大学, 医学部, 講師 2008: Keio University, 医学部, 講師 … More 2007: Tokyo Institute of Technology, バイオフロンティアセンター, 特任助教 2006: 東京工業大学, 大学院生命理工学研究科, COE助手 2005: 東京工業大学, 大学院・生命理工学研究科, COE助手 Less
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Functional biochemistry / Living organism molecular science Except Principal Investigator Pathological medical chemistry
Keywords	Principal Investigator 癌 / 金属タンパク質 / ヘム / 天然有機化合物 / 脂質代謝 / 結晶構造解析 / アポトーシス / 肝機能 / 炎症 / 天然物 … More / ケミカルバイオロジー / 肥満 / がん / 構造生物科学 / がん増殖 / 赤血球分化 / トランスポーター / ミトコンドリア / ヘム生合成 / ポルフィリン / アフィニティ精製 / VDR / 転写因子 / AU rich elemet / mRNA安定性 / ビタミンD / NF-Y / 破骨細胞分化誘導因子 / 骨粗鬆症 … More Except Principal Investigator 糖代謝 / 肝線維化 / lipin-1 / ペルオキシゾーム / 低酸素 / 肝臓 / HIF / 脂肪肝 / 低酸素応答 / 脂質代謝 Less

天然物グリチルリチンの作用を指標とした膜受容体PGRMC1の肝機能・炎症制御の解明Principal Investigator
- Principal Investigator
  
  加部泰明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Keio University
Strategy for improving cancer and obesity by regulating the lipid metabolic function of PGRMC1Principal Investigator
- Principal Investigator
  
  Kabe Yasuaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Keio University
Analyses of physiological function of PGRMC1 based on the structural regulationPrincipal Investigator
- Principal Investigator
  
  Kabe Yasuaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Keio University
Analysis of functional regulation of PGMRC1Principal Investigator
- Principal Investigator
  
  Kabe Yasuaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Keio University
Analysis of erythroid differentiation by HSP27Principal Investigator
- Principal Investigator
  
  KABE Yasuaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Keio University
Analysis of pathological roles of hypoxic responses in the regulation of organ metabolism in fatty liver diseases
- Principal Investigator
  
  GODA Nobuhito
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Waseda University
Analysis of the mitochondrial accumulation of heme precursors for heme biosynthesisPrincipal Investigator
- Principal Investigator
  
  KABE Yasuaka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Keio University
  Tokyo Institute of Technology
破骨細胞分化誘導因子の発現制御機構の解析とこれを標的とした骨阻鬆症薬の開発Principal Investigator
- Principal Investigator
  
  加部泰明
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Tokyo Institute of Technology

[Book] 実験医学別冊「医学生物学における最新プロトコールと実験例」2013
- Author(s)
  加部泰明、末松誠、半田宏
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23570172
[Book] 実験医学別冊「医学生物学における最新プロトコールと実験例」2013
- Author(s)
  加部泰明, 末松誠, 半田宏
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23570172
[Book] 実験医学別冊、質量分析実験ガイド2013
- Author(s)
  加部泰明、末松誠、半田宏
- Publisher
  リガンド結合タンパク質を見つける
- Data Source
  KAKENHI-PROJECT-23570172
[Book] 臨床麻酔「ガス分子による代謝システム制御機構の系統的探索と応用」2012
- Author(s)
  末松誠, 梶村真弓, 加部泰明.
- Publisher
  真興交易医書
- Data Source
  KAKENHI-PROJECT-23570172
[Book] 実験医学「がんと代謝」2012
- Author(s)
  末松誠, 久保亜紀子, 大村光代, 菱木貴子, 梶村真弓, 加部泰明, 杉浦悠基
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23570172
[Book] 実験医学増刊「in vivo実験医学によるヒト疾患解明の最前線」2011
- Author(s)
  末松誠, 梶村真弓, 加部泰明, 山本雄広
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23570172
[Book] Protein Targeting with Small Molecules : Chemical Biology Techniques and Applications2009
- Author(s)
  Yasuaki Kabe
- Publisher
  John Wiley & Sons, Inc.(印刷中)
- Data Source
  KAKENHI-PROJECT-19770105
[Book] Novel application of affinity beads2009
- Author(s)
  Yausaki Kabe, Mamoru Hatakeyama, Kousuke Nishio and Hiroshi Handa
- Publisher
  「Chemical Biology/Chemical Genetics」CMC press(in press)
- Data Source
  KAKENHI-PROJECT-19770105
[Book] Chemical Biology/Chemical Genetics2008
- Author(s)
  Yasuaki Kabe
- Publisher
  CMC press
- Data Source
  KAKENHI-PROJECT-19770105
[Book] ナノアフィニティ磁性ビーズを用いたケミカルバイオロジー戦略、蛋白質核酸酵素2007
- Author(s)
  加部泰明、半田宏
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] PRMT1 Sustains <i>De Novo</i> Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer2024
- Author(s)
  Yamamoto T、Hayashida T、Masugi Y、Oshikawa K、Hayakawa N、Itoh M、Nishime C、Suzuki M、Nagayama A、Kawai Y、Hishiki T、Suematsu M、et al.
- Journal Title
  
  Cancer Research
  
  Volume: 84 Issue: 7 Pages: 1065-1083
- DOI
  10.1158/0008-5472.can-23-2266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05294, KAKENHI-PROJECT-23K11851, KAKENHI-PROJECT-21K06072, KAKENHI-PROJECT-21K06845
[Journal Article] Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery2023
- Author(s)
  Morimoto Satoru、Takahashi Shinichi、Ito Daisuke et al.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 30 Issue: 6 Pages: 766-780.e9
- DOI
  10.1016/j.stem.2023.04.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15736, KAKENHI-PROJECT-22K07500, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-21K07411, KAKENHI-PLANNED-21H05278, KAKENHI-PROJECT-20H00485, KAKENHI-PROJECT-23K21397
[Journal Article] Generation of bicistronic Dmp1-Cre knock-in mice using a self-cleaving 2A peptide2023
- Author(s)
  Nakamura Takashi、Honda Sayako、Ito Shinichirou、Mizoguchi Toshihide、Yamamoto Takehiro、Kasahara Masataka、Kabe Yasuaki、Matsuo Koichi、Suematsu Makoto
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: in printing Issue: 4 Pages: 470-480
- DOI
  10.1007/s00774-023-01425-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19615, KAKENHI-PROJECT-21K06072, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-20H03853, KAKENHI-PROJECT-23K21467
[Journal Article] Polysulfide Serves as a Hallmark of Desmoplastic Reaction to Differentially Diagnose Ductal Carcinoma In Situ and Invasive Breast Cancer by SERS Imaging2023
- Author(s)
  Kubo Akiko、Masugi Yohei、Hase Takeshi、Nagashima Kengo、Kawai Yuko、Takizawa Minako、Hishiki Takako、Shiota Megumi、Wakui Masatoshi、Kitagawa Yuko、Kabe Yasuaki、Sakamoto Michiie、Yachie Ayako、Hayashida Tetsu、Suematsu Makoto
- Journal Title
  
  Antioxidants
  
  Volume: 12 Issue: 2 Pages: 240-240
- DOI
  10.3390/antiox12020240
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05294, KAKENHI-PROJECT-21K06845
[Journal Article] Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s2023
- Author(s)
  Irie Misato、Kabata Hiroki、Sasahara Kotaro、Kurihara Momoko、Shirasaki Yoshitaka、Kamatani Takashi、Baba Rie、Matsusaka Masako、Koga Satoshi、Masaki Katsunori、Miyata Jun、Araki Yasutomo、Kikawada Toru、Kabe Yasuaki、Suematsu Makoto、Yamagishi Mai、Uemura Sotaro、Moro Kazuyo、Fukunaga Koichi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 6 Pages: 112610-112610
- DOI
  10.1016/j.celrep.2023.112610
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08240, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-23K24342
[Journal Article] Pro108Ser mutation of SARS-CoV-2 3CLpro reduces the enzyme activity and ameliorates the clinical severity of COVID-192022
- Author(s)
  Abe K, Kabe Y, Uchiyama S, Iwasaki YW, Ishizu H, Uwamino Y, Takenouchi T, Uno S, Ishii M, Maruno T, Noda M, Murata M, Hasegawa N, Saya H, Kitagawa Y, Fukunaga K, Amagai M, Siomi H, Suematsu M, Kosaki K, Keio Donner Project.
- Journal Title
  
  Sci Rep
  
  Volume: 12 Issue: 1 Pages: 1299-1299
- DOI
  10.1038/s41598-022-05424-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05753, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-22K06091
[Journal Article] ossible Therapeutic Strategy Involving the Purine Synthesis Pathway Regulated by ITK in Tongue Squamous Cell Carcinoma.2021
- Author(s)
  Onidani K, Miura N, Sugiura Y, Abe Y, Watabe Y, Kakuya T, Mori T, Yoshimoto S, Adachi J, Kiyoi T, Kabe Y, Suematsu M, Tomonaga T, Shibahara T, Honda K.
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 13 Pages: 3333-3333
- DOI
  10.3390/cancers13133333
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03749, KAKENHI-PROJECT-20K07333, KAKENHI-PROJECT-20K07383, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-23K20389, KAKENHI-PROJECT-19H03856
[Journal Article] On-tissue polysulfide visualization by surface-enhanced Raman spectroscopy benefits patients with ovarian cancer to predict post-operative chemosensitivity2021
- Author(s)
  Honda Kazufumi、Hishiki Takako、Yamamoto Sohe、Naito Yoshiko、Matsuura Tomomi、Iwaisako Keiko、Masui Toshihiko、Sakuma Tomohiro、Matsubara Osamu、Huang Wilber、Ida Tomoaki、Akaike Takaaki、Masugi Yohei、Sakamoto Michiie、Kato Tomoyasu、Kabe Yasuaki、Suematsu Makoto
- Journal Title
  
  Redox Biology
  
  Volume: 41 Pages: 101926-101926
- DOI
  10.1016/j.redox.2021.101926
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07306, KAKENHI-PROJECT-20K21496, KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-21K05294, KAKENHI-PROJECT-21K06072, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-21K06937, KAKENHI-PROJECT-19H03856
[Journal Article] Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasome complex to prevent Salmonella infection2020
- Author(s)
  Tsugawa Hitoshi、Kabe Yasuaki、Kanai Ayaka、Sugiura Yuki、Hida Shigeaki、Taniguchi Shun’ichiro、Takahashi Toshio、Matsui Hidenori、Yasukawa Zenta、Itou Hiroyuki、Takubo Keiyo、Suzuki Hidekazu、Honda Kenya、Handa Hiroshi、Suematsu Makoto
- Journal Title
  
  PLOS Biology
  
  Volume: 18 Issue: 9 Pages: 3000813-3000813
- DOI
  10.1371/journal.pbio.3000813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07068, KAKENHI-PROJECT-20K06751, KAKENHI-PROJECT-20K07017, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-19H03474, KAKENHI-PROJECT-20H03667, KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18K06921
[Journal Article] O-Glycan-Altered Extracellular Vesicles: A Specific Serum Marker Elevated in Pancreatic Cancer2020
- Author(s)
  Yokose, T., et al., Koshiba, S., et al., Kitagawa, Y.（合計32名、本研究者は26番目）
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 9 Pages: 2469-2469
- DOI
  10.3390/cancers12092469
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-19K18132, KAKENHI-PROJECT-19H03856, KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-18K08552
[Journal Article] Comparative Glycomic Analysis of Exosome Subpopulations Derived from Pancreatic Cancer Cell Lines2020
- Author(s)
  Matsuda Atsushi、Kuno Atsushi、Yoshida Maki、Wagatsuma Takanori、Sato Takashi、Miyagishi Makoto、Zhao Jing、Suematsu Makoto、Kabe Yasuaki、Narimatsu Hisashi
- Journal Title
  
  Journal of Proteome Research
  
  Volume: 19 Issue: 6 Pages: 2516-2524
- DOI
  10.1021/acs.jproteome.0c00200
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16078, KAKENHI-PROJECT-18K06921
[Journal Article] Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes2020
- Author(s)
  Furuhata Ryogo、Kabe Yasuaki、Kanai Ayaka、Sugiura Yuki、Tsugawa Hitoshi、Sugiyama Eiji、Hirai Miwa、Yamamoto Takehiro、Koike Ikko、Yoshikawa Noritada、Tanaka Hirotoshi、Koseki Masahiro、Nakae Jun、Matsumoto Morio、Nakamura Masaya、Suematsu Makoto
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 479-479
- DOI
  10.1038/s42003-020-01202-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-19K07068, KAKENHI-PROJECT-19K08973, KAKENHI-PROJECT-20K08214, KAKENHI-PROJECT-20K08881, KAKENHI-PROJECT-18H03532, KAKENHI-PROJECT-18K06921
[Journal Article] Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites.2020
- Author(s)
  Kabe Y, Takemoto D, Kanai A, Hirai M, Ono Y, Akazawa S, Horikawa M, Kitagawa Y, Handa H, Rogi T, Shibata H, Suematsu M.
- Journal Title
  
  npj Science of Food
  
  Volume: 4 Issue: 1
- DOI
  10.1038/s41538-020-0064-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-17H06112
[Journal Article] Application of high-performance magnetic nanobeads to biological sensing devices2019
- Author(s)
  Kabe Yasuaki、Sakamoto Satoshi、Hatakeyama Mamoru、Yamaguchi Yuki、Suematsu Makoto、Itonaga Makoto、Handa Hiroshi
- Journal Title
  
  Analytical and Bioanalytical Chemistry
  
  Volume: 411 Issue: 9 Pages: 1825-1837
- DOI
  10.1007/s00216-018-1548-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-18K06921
[Journal Article] Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo.2019
- Author(s)
  Kobayashi H, Morikawa T, Okinaga A, Hamano F, Hashidate-Yoshida T, Watanuki S, Hishikawa D, Shindou H, Arai F, Kabe Y, Suematsu M, Shimizu T, Takubo K.
- Journal Title
  
  Cell Reports
  
  Volume: 28 Issue: 1 Pages: 145-158
- DOI
  10.1016/j.celrep.2019.06.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-18K08379, KAKENHI-PROJECT-19K22638, KAKENHI-PROJECT-19K17847, KAKENHI-PROJECT-17H04208, KAKENHI-PROJECT-18H02845, KAKENHI-PROJECT-18K19570
[Journal Article] Xanthine oxidase inhibitor ameliorates postischemic renal injury in mice by promoting resynthesis of adenine nucleotides.2019
- Author(s)
  Fujii K, Kubo A, Miyashita K, Sato M, Hagiwara A, Inoue H, Ryuzaki M, Tamaki M, Hishiki T, Hayakawa N, Kabe Y, Itoh H, Suematsu M.
- Journal Title
  
  JCI insight
  
  Volume: 4 Issue: 22 Pages: 124816-124816
- DOI
  10.1172/jci.insight.124816
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-19K17717, KAKENHI-PROJECT-17H06270, KAKENHI-PROJECT-17K09710, KAKENHI-PROJECT-17K09735
[Journal Article] Function and structural regulation of the carbon monoxide (CO)-responsive membrane protein PGRMC12018
- Author(s)
  Kabe Y, Handa H, Suematsu M.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 63 Issue: 1 Pages: 12-17
- DOI
  10.3164/jcbn.17-132
- NAID
  130007387128
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06921
[Journal Article] Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor-Initiating Stem Cell-Like Cells Resistant to mTORC1 Inhibition.2018
- Author(s)
  Wu R, Murali R, Kabe Y, French SW, Chiang YM, Liu S, Sher L, Wang CC, Louie S, Tsukamoto H.
- Journal Title
  
  Hepatology
  
  Volume: 68 Issue: 5 Pages: 1726-1740
- DOI
  10.1002/hep.30071
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06921
[Journal Article] Development of a Highly Sensitive Device for Counting the Number of Disease-Specific Exosomes in Human Sera.2018
- Author(s)
  Kabe Y, Suematsu M, Sakamoto S, Hirai M, Koike I, Hishiki T, Matsuda A, Hasegawa Y, Tsujita K, Ono M, Minegishi N, Hozawa A, Murakami Y, Kubo M, Itonaga M, Handa H.
- Journal Title
  
  Clin Chem
  
  Volume: 64 Issue: 10 Pages: 1463-1473
- DOI
  10.1373/clinchem.2018.291963
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-15K09464, KAKENHI-PROJECT-16K01937
[Journal Article] Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival2018
- Author(s)
  Shiota M, Naya M, Yamamoto T, Hishiki T, Tani T, Takahashi H, Kubo A, Koike D, Itoh M, Ohmura M, Kabe Y, Sugiura Y, Hiraoka N, Morikawa T, Takubo K, Suina K, Nagashima H, Sampetrean O, Nagano O, Saya H, Yamazoe S, Watanabe H, Suematsu M
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 1561-1561
- DOI
  10.1038/s41467-018-03899-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01937, KAKENHI-PROJECT-15H04355, KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-15K10315, KAKENHI-PROJECT-18K06921, KAKENHI-PROJECT-18K08379, KAKENHI-PROJECT-17K19614, KAKENHI-PROJECT-16K07124, KAKENHI-PROJECT-18J14396
[Journal Article] Quiescence of adult oligodendrocyte precursor cells requires thyroid hormone and hypoxia to activate Runx1.2017
- Author(s)
  Tokumoto Y, Tamaki S, Kabe Y, Takubo K, Suematsu M
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1019-1019
- DOI
  10.1038/s41598-017-01023-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07011, KAKENHI-PLANNED-26115005, KAKENHI-PROJECT-15H04861, KAKENHI-PROJECT-16K15507
[Journal Article] Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism2017
- Author(s)
  Nishimoto, K., Koga, M., Seki, T., Oki, K., Gomez-Sanchez, E.P., Gomez-Sanchez, C.E., Naruse, M., Sakaguchi, T., Morita, S., Kosaka, T., Oya, M., Ogishima, T., Yasuda, M., Suematsu, M., Kabe, T., Omura, M., Nishikawa, T., Mukai, K.
- Journal Title
  
  Mol. Cell. Endocrinol.
  
  Volume: 441 Pages: 124-133
- DOI
  10.1016/j.mce.2016.10.014
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461387, KAKENHI-PROJECT-26860707, KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-15K10650
[Journal Article] CO応答性ヘムタンパク質PGRMC1による悪性腫瘍の増殖と薬剤耐性のメカニズムの解明2017
- Author(s)
  加部泰明、末松誠
- Journal Title
  
  生化学
  
  Volume: 89 Pages: 88-88
- NAID
  40021439299
- Data Source
  KAKENHI-PROJECT-15K07011
[Journal Article] Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.2017
- Author(s)
  Lai KK, Kweon SM, Chi F, Hwang E, Kabe Y, Higashiyama R, Qin L, Yan R, Wu RP, Fujii N, French S, Xu J, Wang JY, Murali R, Mishra L, Lee JS, Ntambi JM, Tsukamoto H.
- Journal Title
  
  Gastroenterology
  
  Volume: S0016-5085 Issue: 6 Pages: 300081-300081
- DOI
  10.1053/j.gastro.2017.01.021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07011
[Journal Article] Disorganized steroidogenesis in adrenocortical carcinoma, a case study2017
- Author(s)
  Uchida, T., Nishimoto, K., Fukumura, Y., Asahina, M., Goto, H., Kawano, Y., Shimizu, F., Tsujimura, A., Seki, T., Mukai, K., Kabe, Y., Suematsu, M., Gomez-Sanchez, C.E., Yao, T., Horie, S., Watada, H.
- Journal Title
  
  Endocr. Pathol.
  
  Volume: 28 Issue: 1 Pages: 27-35
- DOI
  10.1007/s12022-016-9441-8
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461387, KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-15K10650
[Journal Article] Somatic KCNJ5 mutation occurring early in adrenal development may cause a novel form of juvenile primary aldosteronism.2017
- Author(s)
  Tamura A, Nishimoto K, Seki T, Matsuzawa Y, Saito J, Omura M, Gomez-Sanchez CE, Makita K, Matsui S, Moriya N, Inoue A, Nagata M, Sasano H, Nakamura Y, Yamazaki Y, Kabe Y, Mukai K, Kosaka T, Oya M, Suematsu S, Nishikawa T.
- Journal Title
  
  Mol Cell Endocrinol.
  
  Volume: 441 Pages: 134-139
- DOI
  10.1016/j.mce.2016.07.031
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04711, KAKENHI-PROJECT-26461387, KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-15K10650
[Journal Article] Cystathionine beta-synthase and PGRMC1 as CO sensors.2016
- Author(s)
  Kabe Y, Yamamoto T, Kajimura M, Sugiura Y, Koike I, Ohmura M, Nakamura T, Tokumoto Y, Tsugawa H, Handa H, Kobayashi T, and Suematsu M.
- Journal Title
  
  Free Radical Biology & Medicine
  
  Volume: 99 Pages: 333-344
- DOI
  10.1016/j.freeradbiomed.2016.08.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04355, KAKENHI-PROJECT-26560469, KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-16K07066
[Journal Article] Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.2016
- Author(s)
  Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, Sugase K, Shimamura T, Ohmura M, Muraoka K, Yamamoto A, Uchida T, Iwata S, Yamaguchi Y, Krayukhina E, Noda M, Handa H, Ishimori K, Uchiyama S, Kobayashi T, Suematsu M.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 11030-11030
- DOI
  10.1038/ncomms11030
- NAID
  130007529314
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07011, KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-16H06145
[Journal Article] Human Adrenocortical Remodeling Leading to Aldosterone-Producing Cell Cluster Generation.2016
- Author(s)
  Nishimoto K, Seki T, Hayashi Y, Mikami S, Al-Eyd G, Nakagawa K, Morita S, Kosaka T, Oya M, Mitani F, Suematsu M, Kabe Y, Mukai K.
- Journal Title
  
  Int J Endocrinol.
  
  Volume: 2016 Pages: 7834356-7834356
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07011
[Journal Article] Alteration of matrix metalloproteinase-3 O-glycan structure as a biomarker for disease activity of rheumatoid arthritis.2016
- Author(s)
  Takeshita M, Kuno A, Suzuki K, Matsuda A, Shimazaki H, Nakagawa T, Otomo Y, Kabe Y, Suematsu M, Narimatsu H, Takeuchi T.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 18 Issue: 1 Pages: 112-112
- DOI
  10.1186/s13075-016-1013-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07011
[Journal Article] Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1.2016
- Author(s)
  Pati ML, Groza D, Riganti C, Kopecka J, Niso M, Berardi F, Hager S, Heffeter P, Hirai M, Tsugawa H, Kabe Y, Suematsu M, Abate C.
- Journal Title
  
  Pharmacological Research
  
  Volume: 117 Pages: 67-71
- DOI
  10.1016/j.phrs.2016.12.023
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-16K08349
[Journal Article] CO-CBS-H2 S Axis: From Vascular Mediator to Cancer Regulator.2016
- Author(s)
  Suematsu M, Nakamura T, Tokumoto Y, Yamamoto T, Kajimura M, Kabe Y.
- Journal Title
  
  Microcirculation
  
  Volume: 23 Issue: 3 Pages: 183-190
- DOI
  10.1111/micc.12253
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07011, KAKENHI-PUBLICLY-26117726, KAKENHI-PROJECT-26670673, KAKENHI-PROJECT-15H04355, KAKENHI-PROJECT-16K07066
[Journal Article] LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.2015
- Author(s)
  Masuda K, Chiyoda T, Sugiyama N, Segura-Cabrera A, Kabe Y, Ueki A, Banno K, Suematsu M, Aoki D, Ishihama Y, Saya H, Kuninaka S
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 2 Pages: 1-22
- DOI
  10.1371/journal.pone.0118662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24241062, KAKENHI-PROJECT-24590360, KAKENHI-PROJECT-26830125, KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-15K20161, KAKENHI-PROJECT-14J04635
[Journal Article] Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry.2014
- Author(s)
  Ohmura M, Hishiki T, Yamamoto T, Nakanishi T, Kubo A, Tsuchihashi K, Tamada M, Toue S, Kabe Y, Saya H and Suematsu M
- Journal Title
  
  Nitric Oxide
  
  Volume: pii: S1089-8603 Pages: 495-499
- DOI
  10.1016/j.niox.2014.11.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-24510304, KAKENHI-PROJECT-25870717, KAKENHI-PUBLICLY-26117726, KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-25513008
[Journal Article] Microscopic imaging mass spectrometry assisted by on-tissue chemical derivatization for visualizing multiple amino acids in human colon cancer xenografts.2014
- Author(s)
  Toue S, Sugiura Y, Kubo A, Ohmura M, Karakawa S, Mizukoshi T, Yoneda J, Miyano H, Noguchi Y, Kobayshi T, Kabe Y, Suematsu M.
- Journal Title
  
  Proteomics
  
  Volume: 14 Issue: 7-8 Pages: 810-819
- DOI
  10.1002/pmic.201300041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172, KAKENHI-PROJECT-25513008
[Journal Article] Microscopic imaging mass spectrometry assisted by on-tissue chemical derivatization for visualizing multiple amino acids in human colon cancer xenografts2013
- Author(s)
  Toue S, Sugiura Y, Kubo A, Ohmura M, Karasawa S, Mizukoshi M, Yoneda J, MIyano H, Noguchi Y, KObayashi T, Kabe Y, Suematsu M
- Journal Title
  
  Proteomics
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Microscopic imaging mass spectrometry assisted by on-tissue chemical derivatization for visualizing multiple amino acids in human colon cancer xenografts2013
- Author(s)
  Toue S, Sugiura Y, Kubo A, Ohmura M, Karakawa S, Mizukoshi T, Yoneda J, Miyano H, Noguchi Y, Kobayshi T, Kabe Y, Suematsu M.
- Journal Title
  
  Proteomics
  
  Volume: 14(7-8) Pages: 810-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Vesnarinone Suppresses TNF α mRNA Expression by Inhibiting Valosin-containing Protein2013
- Author(s)
  Hotta K, Nashimoto A, Yasumura E, Suzuki M, Azuma M, Iizumi Y, Shima D, Nabeshima R, Hiramoto M, Okada A, Sakata-Sogawa K, Tokunaga M, Ito T, Ando H, Sakamoto S, Kabe Y, Aizawa S, Imai T, Yamaguchi Y, Watanabe H, Handa H
- Journal Title
  
  Mol Pharmacol
  
  Volume: Vol.83 Issue: 5 Pages: 930-938
- DOI
  10.1124/mol.112.081935
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20114004, KAKENHI-PLANNED-23102004, KAKENHI-PROJECT-23570172, KAKENHI-PROJECT-23689036, KAKENHI-PROJECT-23710267, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-24650231, KAKENHI-PLANNED-23102002, KAKENHI-PLANNED-24118006
[Journal Article] Vesnarinone Suppresses TNFα mRNA Expression by Inhibiting Valosin-containing Protein.2013
- Author(s)
  Hotta K, Nashimoto A, Yasumura E, Suzuki M, Azuma M, Iizumi Y, Shima D, Ando H, Sakamoto S, Kabe Y, Aizawa S, Imai T, Yamaguchi Y, Watanabe H, Handa H.
- Journal Title
  
  Mol Pharmacol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Vesnarinone suppresses TNFαmRNA expression by inhibiting valosin-containing protein2013
- Author(s)
  Hotta K, Nashimoto A, Yasumura E, Suzuki M, Azuma M, Iizumi Y, Shima D, Nabeshima R, Hiramoto M, Okada A, Sakata-Sogawa K, Tokunaga M, Ito T, Ando H, Sakamoto S, Kabe Y, Aizawa S, Imai T, Yamaguchi Y, Watanabe H, Handa H.
- Journal Title
  
  Mol Pharmacol
  
  Volume: 83(5) Pages: 930-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Vitamin K2 covalently binds to Bak and induces Bak-mediated apoptosis2013
- Author(s)
  Karasawa S, Azuma M, Kasama T, Sakamoto S, Kabe Y, Imai T, Yamaguchi Y, Miyazawa K, Handa H.
- Journal Title
  
  Mol Pharmacol
  
  Volume: 83(3) Pages: 613-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Vitamin K2 covalently binds to Bak and induces Bak-mediated apoptosis.2013
- Author(s)
  Karasawa S, Azuma M, Kasama T, Sakamoto S, Kabe Y, Imai T, Yamaguchi Y, Miyazawa K, Handa H
- Journal Title
  
  Mol Pharmacol
  
  Volume: 83 Issue: 3 Pages: 613-620
- DOI
  10.1124/mol.112.082602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591050, KAKENHI-PROJECT-23570172, KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002
[Journal Article] Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway.2012
- Author(s)
  Morikawa T, Kajimura M, Nakamura T, Hishiki T,Ishikawa M, Hattori K, Takenouchi T, Takahashi T, Ishii I, Matsubara K, Kabe Y, Uchiyama S, Nagata E, Gadalla MM, Snyder SH, Suematsu M.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109 Pages: 1293-1298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] HIF-1αinduction suppresses excessive lipid accumulation in alcoholic fatty liver in mice2012
- Author(s)
  Nishiyama Y, Goda N, Kanai M, Niwa D, Osanai K, Yamamoto Y, Senoo-Matsuda N, Johnson RS, Miura S, Kabe Y, Suematsu M.
- Journal Title
  
  J Hepatol.
  
  Volume: 56(2) Pages: 441-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Involvement of NF-κB-mediated expression of galectin-3-binding protein in TNF-α-induced breast cancer cell adhesion2012
- Author(s)
  Noma N, Simizu S, Kambayashi Y, Kabe Y, Suematsu M, Umezawa K.
- Journal Title
  
  Oncol Rep
  
  Volume: 27(6) Pages: 2080-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway2012
- Author(s)
  Morikawa T, Kajimura M, Nakamura T, Hishiki T, Nakanishi T, Yukutake Y, Nagahata Y, Ishikawa M, Hattori K, Takenouchi T, Takahashi T, Ishii I, Matsubara K, Kabe Y, Uchiyama S, Nagata E, Gadalla MM, Snyder SH, Suematsu M.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 109(4) Pages: 1293-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Involvement of NF-κB-mediated expression of galectin-3-binding protein in TNF-α-induced breast cancer cell adhesion.2012
- Author(s)
  Noma N, Simizu S, Kambayashi Y, Kabe Y, Suematsu M, Umezawa K
- Journal Title
  
  Oncology Reports
  
  Volume: 27 Pages: 2080-2084
- URL
  http://www.spandidos-publications.com/serveFile/or_27_6_2080_PDF.pdf?type=article&article_id=or_27_6_2080&item=PDF
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice.2012
- Author(s)
  Nishiyama Y, Goda N, Kanai M, Niwa D, Osanai K, Yamamoto Y, Senoo-Matsuda N, Johnson RS, Miura S, Kabe Y, Suematsu M.
- Journal Title
  
  J Hepatol.
  
  Volume: 56 Pages: 441-447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Involvement of NF-κB-mediated expression of galectin-3-binding protein in TNF-α-induced breast cancer cell adhesion.2012
- Author(s)
  Noma N, Simizu S, Kambayashi Y, Kabe Y, Suematsu M, Umezawa K.
- Journal Title
  
  Oncol Rep.
  
  Volume: 27 Pages: 2080-2084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway.2011
- Author(s)
  Morikawa T, Kajimura M, Nakamura T, Kabe Y,　et al
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109 Pages: 1293-1298
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268316/pdf/pnas.201119658.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice.2011
- Author(s)
  Nishiyama Y, Goda N, Kanai M, Niwa D, Osanai K, Yamamoto Y, Senoo-Matsuda N, Johnson RS, Miura S, Kabe Y, Suematsu M.
- Journal Title
  
  Journal of Hepatology
  
  Volume: 56 Pages: 441-447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Gas Biology Research in Clinical Practice : Roles of Stress-Inducible Carbon Monoxide in the Regulation of Liver Function2011
- Author(s)
  Suematsu M, Kajimura M, Kabe Y.
- Journal Title
  
  KARGAR press
  
  Pages: 1-5
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Identification of dynamin-2-mediated endocytosis as a new target of osteoporosis drugs, bisphosphonates2011
- Author(s)
  Masaike Y, Takagi T, Hirota M, Yamada J, Ishihara S, Yung TM, Inoue T, Sawa C, Sagara H, Sakamoto S, Kabe Y, Takahashi Y, Yamaguchi Y, Handa H.
- Journal Title
  
  Mol Pharmacol.
  
  Volume: 77(2) Pages: 262-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570172
[Journal Article] Mono-(2-ethylhexyl) phthalate targets glycogen debranching enzyme and affects glycogen metabolism in rat testis2009
- Author(s)
  Kuramori C, Hase Y, Hoshikawa K, Watanabe K, Nishi T, Hishiki T, Soga T, Nashimoto A, Kabe Y, Yamaguchi Y, Watanabe H, Kataoka K, Suematsu M, Handa H
- Journal Title
  
  Toxicol Sci 109(1)
  
  Pages: 143-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus2009
- Author(s)
  Kuramori C, Azuma M, Kume K, Kaneko Y, Inoue A, Yamaguchi Y, Kabe Y, Hosoya T, Kizaki M, Suematsu M, Handa H
- Journal Title
  
  Biochem Biophys Res Commun 379(2)
  
  Pages: 519-525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] Development and application of high-performance affinity beads : toward chemical biology and drug discovery2009
- Author(s)
  Sakamoto S, Kabe Y, Hatakeyama M, Yamaguchi Y, Handa H
- Journal Title
  
  Chem Rec 9(1)
  
  Pages: 66-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] Adenine nucleotide translocator transports haem precursors into mitochondria2008
- Author(s)
  Azuma M*, Kabe Y*, Kuramori C, Kondo M, Yamaguchi Y, Handa H. (*double first authorship)
- Journal Title
  
  PLoS ONE 3(8)
  
  Pages: 3070-3070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity2008
- Author(s)
  Ando K, Hirao S, Kabe Y, Ogura Y, Sato I, Yamaguchi Y, Wada T, Handa H
- Journal Title
  
  Nucleic Acids Res 36(13)
  
  Pages: 4327-43361
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] A new mechanism of 6-((2-(dimethylamino)ethyl)amino)-3-hyd roxy-7H-indeno(2,1-c)quinolin-7-one dihydrochloride (TAS-103) action discovered by target screening with drug-immobilized affinity beads2008
- Author(s)
  Yoshida M, Kabe Y, Wada T, Asai A, Handa H
- Journal Title
  
  Mol Pharmacol 73(3)
  
  Pages: 987-994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] Development of a chemical screening system using aqueorin-fused protein2008
- Author(s)
  Suzuki M, Furukawa S, Kuramori C, Sawa C, Kabe Y, Nakamura M, Sawada J, Yamaguchi Y, Sakamoto S, Inouye S, Handa H
- Journal Title
  
  Biochem Biophys Res Commun 368(3)
  
  Pages: 600-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells : therapeutic implications in tumor angiogenesis2008
- Author(s)
  Zou GM, Karikari C, Kabe Y, Handa H, Anders RA, Maitra A
- Journal Title
  
  J Cell Physiol 219(1)
  
  Pages: 209-218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] Atrazine binds to F1F0-ATP synthase and inhibits mitochondrial function in sperm2008
- Author(s)
  Hase Y, Tatsuno M, Nishi T, Kataoka K, Kabe Y, Yamaguchi Y, Ozawa N, Natori M, Handa H, Watanabe H
- Journal Title
  
  Biochem Biophys Res Commun 366(1)
  
  Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] The enteropathogeni E. coli effector EspB facilitates microvillus effacing and antiphagocytosis by inhibiting myosin function2007
- Author(s)
  Iizumi Y, Sagara H, Kabe Y, Azuma M, Kume K, Ogawa M, Nagai T, Gillespie PG, Sasakawa C, Handa H
- Journal Title
  
  Cell Host Microbe 2(6)
  
  Pages: 383-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770105
[Journal Article] Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier.2006
- Author(s)
  Kabe Y, Ohmori M, Shinouchi K, Tsuboi Y, Hirao S, Azuma M, Watanabe H, Okura I, Handa H
- Journal Title
  
  J Biol Chem. 281
  
  Pages: 31729-31735
- Data Source
  KAKENHI-PROJECT-17710183
[Journal Article] hnRNP-U enhances the expression of specific genes by stabilizing mRNA.2006
- Author(s)
  Yugami M, Kabe Y, Yamaguchi Y, Wada T, Handa H
- Journal Title
  
  Febs Letters 581
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-17710183
[Journal Article] TFII-I downregulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor.2006
- Author(s)
  Yuji Ogura, Motoki Azuma, Yasuaki Tsuboi, Yasuaki Kabe, Yuki Yamaguchi, Tadashi Wada, Hiroshi Handa
- Journal Title
  
  Genes to Cells (In printing)
- Data Source
  KAKENHI-PROJECT-17710183
[Journal Article] TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor alpha.2006
- Author(s)
  Ogura Y, Azuma M, Tsuboi Y, Kabe Y, Yamaguchi Y, Wada T, Watanabe H, Handa H
- Journal Title
  
  Genes to Cells 11
  
  Pages: 373-381
- Data Source
  KAKENHI-PROJECT-17710183
[Journal Article] NF-Y is Essential for the Recruitment of RNA Polymerase II and Inducible Transcription of Several CCAAT Box-Containing Genes.2005
- Author(s)
  Yasuaki Kabe, Joe Yamada, Hitoshi Uga, Yuki Yamaguchi, Tadashi Wada, Hiroshi Handa.
- Journal Title
  
  Molecular Cellular Biology 25
  
  Pages: 512-522
- Data Source
  KAKENHI-PROJECT-17710183
[Journal Article] GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis.2005
- Author(s)
  Delehouzee S, Yoshikawa T, Sawa C, Sawada J, Ito T, Omori M, Wada T, Yamaguchi Y, Kabe Y, Handa H.
- Journal Title
  
  Genes to Cells 10
  
  Pages: 717-732
- Data Source
  KAKENHI-PROJECT-17710183
[Patent] 一酸化炭素（CO）による脂肪酸、コレステロールの取り込み阻害2011
- Inventor(s)
  加部泰明、末松誠
- Industrial Property Rights Holder
  加部泰明、末松誠
- Filing Date
  2011
- Data Source
  KAKENHI-PROJECT-23570172
[Patent] 一酸化炭素(CO)による脂肪酸、コレステロールの取り込み阻害2011
- Inventor(s)
  加部泰明, 末松誠
- Industrial Property Rights Holder
  加部泰明, 末松誠
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2011-263015
- Filing Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] Development of a medical application using nano-beads technology2019
- Author(s)
  Yasuaki Kabe
- Organizer
  The 92nd Annual Meeting of the Japanese Biochemical Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06921
[Presentation] ヘム含有受容体PGRMC1の構造と機能2017
- Author(s)
  加部泰明
- Organizer
  第41回日本鉄バイオサイエンス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15K07011
[Presentation] 新規ガス受容体PGRMC1の構造的機能制御の解明2016
- Author(s)
  加部泰明
- Organizer
  日本プロテオーム学会2016年大会
- Place of Presentation
  北里大学白金キャンパス
- Year and Date
  2016-07-27
- Data Source
  KAKENHI-PROJECT-15K07011
[Presentation] 新規ガス受容体PGRMC1の構造的機能制御の解明2016
- Author(s)
  加部泰明
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K07011
[Presentation] 肝炎保護成分グリチルリチンの新規受容体探索と生理機能の解明2015
- Author(s)
  加部泰明
- Organizer
  第22回肝細胞研究会
- Place of Presentation
  米子コンベンションセンター（鳥取県米子市）
- Year and Date
  2015-06-04
- Invited
- Data Source
  KAKENHI-PROJECT-15K07011
[Presentation] 新規 CO ガス受容体を介した肝障害制御機構の解明2014
- Author(s)
  加部泰明
- Organizer
  第12回分子予防環境医学研究会
- Place of Presentation
  つくばサイエンス・インフォメーションセンター
- Invited
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] 新規COガス受容体を介した肝障害制御機構の解明2013
- Author(s)
  加部泰明
- Organizer
  第12回分子予防環境医学研究会
- Place of Presentation
  つくばサイエンス・インフォメーションセンター
- Year and Date
  2013-02-01
- Invited
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] ヘム/COによるGAPDHを介した細胞防御機構の解明2012
- Author(s)
  加部泰明, 末松誠
- Organizer
  第35回日本分子生物学会年回
- Place of Presentation
  福岡国際会議場 (口頭・ポスター発表)
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] Regulation of the GAPDH-mediated cell death by CO gas2012
- Author(s)
  加部泰明、半田宏、末松誠
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] ヘム/COによる細胞防御機構の解明2011
- Author(s)
  加部泰明, 末松誠
- Organizer
  第32回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館口頭発表)
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] ガス分子応答性受容体の系統的探索機能解明2011
- Author(s)
  加部泰明、内田毅、山本竜也、堀内正、石森浩一郎、半田宏、末松誠
- Organizer
  第64回日本酸化ストレス学会
- Place of Presentation
  北海道ルスツリゾートホテル（北海道）
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] Carbon Monoxide Protects Against the GAPDH-mediated Cell Death2011
- Author(s)
  加部泰明、山本竜也、半田宏、末松誠
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] ヘム/COによるGAPDHを介した細胞防御機構の解明2011
- Author(s)
  加部　泰明、半田　宏、末松　誠
- Organizer
  日本ケミカルバイオロジー学会　第6回年会
- Place of Presentation
  東京工業大学大岡山キャンパス（東京都）
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] ヘム/COによるGAPDHを介した細胞防御機構の解明2011
- Author(s)
  加部泰明, 末松誠
- Organizer
  第38回生体分子科学討論会
- Place of Presentation
  筑波大学大学会館国際会議室口頭発表)
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] COガスによる細胞防御機構の解明2011
- Author(s)
  加部泰明, 末松誠
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (口頭・ポスター発表)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] ガス分子応答性受容体の系統的探索と機能解明2011
- Author(s)
  加部泰明, 末松誠
- Organizer
  第64回日本酸化ストレス学会
- Place of Presentation
  北海道ルスツリゾートホテル&コンベンション (口頭発表)
- Year and Date
  2011-07-03
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] ヘム/COによるGAPDHを介した細胞防御機構の解明2011
- Author(s)
  加部泰明、内田毅、山本竜也、石森浩一郎、半田宏、末松誠
- Organizer
  第38回生体分子科学討論会
- Place of Presentation
  筑波大学（茨城県）
- Data Source
  KAKENHI-PROJECT-23570172
[Presentation] 赤血球分化におけるヘム毒性に対する生体防御機構2008
- Author(s)
  加部泰明
- Organizer
  第3回ケミカルバイオロジー学会
- Place of Presentation
  東京
- Year and Date
  2008-06-18
- Data Source
  KAKENHI-PROJECT-19770105
[Presentation] HSP27を介したヘム毒性に対する細胞防御機構2008
- Author(s)
  加部泰明
- Organizer
  第31回日本分子生物学学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19770105
[Presentation] HSP27 を介したヘム毒性に対する生体防御機構2008
- Author(s)
  加部泰明
- Organizer
  第31 回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19770105
[Presentation] ヘム生合成に関わるヘム前駆体のミトコンドリア集積機構の解析2007
- Author(s)
  加部泰明
- Organizer
  第3回ケミカルバイオロジー学会
- Place of Presentation
  京都
- Year and Date
  2007-05-09
- Data Source
  KAKENHI-PROJECT-19770105
[Presentation] ヘム刺激による赤血球分化における細胞防御機構の解析2007
- Author(s)
  加部泰明
- Organizer
  第30 回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19770105
[Presentation] ヘム刺激による赤血球分化における細胞防御機構の解析2007
- Author(s)
  加部泰明
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜みなと未来
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19770105
[]
[]

1. ISHIMORI Koichiro (20192487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. GODA Nobuhito (00245549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TSUKADA Kosuke (00351883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. UCHIDA Tsuyoshi (30343742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 山崎広貴 (60784337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TSUGAWA Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ISHIHAMA YASUSHI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. SUGIYAMA Naoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. YAMAZAKI Yuto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 菱木貴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 山口雄輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 半田宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 森本悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 塩見春彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 溝口利英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 十川久美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 徳永万喜洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 荻島正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 向井邦晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 佐谷秀行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 小柴生造

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 山本雄広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 松田厚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 田中廣壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 朝長毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 加畑宏樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 井田智章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 中村保宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 笹野公伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. Gomez-Sanchez Celso E

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 宮澤啓介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kabe Yasuaki 加部 泰明

KABE Yasuaki 加部 泰明

KABE Yasuaka 加部 泰明

Research Projects

Research Products

Co-Researchers

天然物グリチルリチンの作用を指標とした膜受容体PGRMC1の肝機能・炎症制御の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Strategy for improving cancer and obesity by regulating the lipid metabolic function of PGRMC1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of physiological function of PGRMC1 based on the structural regulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of functional regulation of PGMRC1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of erythroid differentiation by HSP27Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of pathological roles of hypoxic responses in the regulation of organ metabolism in fatty liver diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mitochondrial accumulation of heme precursors for heme biosynthesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

破骨細胞分化誘導因子の発現制御機構の解析とこれを標的とした骨阻鬆症薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 実験医学別冊「医学生物学における最新プロトコールと実験例」2013

Author(s)

Publisher

Data Source

[Book] 実験医学別冊「医学生物学における最新プロトコールと実験例」2013

Author(s)

Publisher

Data Source

[Book] 実験医学別冊、質量分析実験ガイド2013

Author(s)

Publisher

Data Source

[Book] 臨床麻酔「ガス分子による代謝システム制御機構の系統的探索と応用」2012

Author(s)

Publisher

Data Source

[Book] 実験医学「がんと代謝」2012

Author(s)

Publisher

Data Source

[Book] 実験医学増刊「in vivo実験医学によるヒト疾患解明の最前線」2011

Author(s)

Publisher

Data Source

[Book] Protein Targeting with Small Molecules : Chemical Biology Techniques and Applications2009

Author(s)

Kabe Yasuaki 加部泰明

KABE Yasuaki 加部泰明

KABE Yasuaka 加部泰明