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Yao Chenjuan  姚 陳娟

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YAO Chenjuan  姚 陳娟

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Researcher Number 20432750
Affiliation (Current) 2025: 徳島大学, 大学院医歯薬学研究部(歯学域), 助教
Affiliation (based on the past Project Information) *help 2024 – 2025: 徳島大学, 大学院医歯薬学研究部(歯学域), 助教
2016: 徳島大学, 大学院医歯薬学研究部(歯学系), 助教
2015: 徳島大学, 大学院医歯薬学研究部, 助教
2012 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教
2013: 徳島大学, 大学院ヘルスバイオサイエンス 研究部(歯学系), 助教 … More
2008 – 2009: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 助教
2007: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授
2006: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 57010:Oral biological science-related / Functional basic dentistry
Except Principal Investigator
Functional basic dentistry / Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 59040:Nutrition science and health science-related
Keywords
Principal Investigator
Naポンプ / NF-κBシグナリング / down-regulation / 水チャネル / 唾液腺 / LPS / 口腔生理学
Except Principal Investigator
唾液腺 / AQP5 / 水チャネル … More / PACE4 / サチライシン様前駆体蛋白質変換酵素 / 顎下腺 / Wnt / 幹細胞 / アクアポリン5 / フラボノイド / 口腔乾燥症 / 雌雄差 / 再生 / HSG細胞 / bHLH型転写因子 / 発生・分化・再生 / 腺房細胞 / GFP-AQP5キメラ分子 / トラフィッキング / MDCK細胞 / 塩酸セビメリン / 副交感神経 / カテプシン / アクアポリン Less
  • Research Projects

    (7 results)
  • Research Products

    (40 results)
  • Co-Researchers

    (13 People)
  •  Elucidation of the Function of Embryonic-Like Revertant Stem Cells in Salivary Gland Repair and Establishment of a Basis for Regenerative Therapy

    • Principal Investigator
      松本 真司
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      The University of Tokushima
  •  Na+/K+-ATPase α1の選択的分解を介した唾液腺慢性ストレス応答機構の分子基盤解明Principal Investigator

    • Principal Investigator
      姚 陳娟
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      The University of Tokushima
  •  フラボノイドの唾液腺機能亢進効果の検証:口腔乾燥症予防に資する機能性食品の開発

    • Principal Investigator
      赤松 徹也
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      The University of Tokushima
  •  Elucidation of Molecular Mechanism of the Salivary Gland Regeneration ~ Toward the application to the Regenerative Medicine for Xerostomia ~

    • Principal Investigator
      Akamatsu Tetsuya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      The University of Tokushima
  •  Elucidation of the molecular mechanism on the differentiation/maturation and functional expression of salivary acinar cell toward conquest of xerostomia.

    • Principal Investigator
      AKAMATSU Tetsuya
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      The University of Tokushima
  •  Down-regulation of salivary glands AQP5 by LPS via NF-κB signalingPrincipal Investigator

    • Principal Investigator
      YAO Chenjuan
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      The University of Tokushima
  •  Moecular meohanism of expression and regulation of the water channe1, aquapor in 5 in the exocrine gland

    • Principal Investigator
      HOSOI Kazuo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      The University of Tokushima

All 2016 2014 2013 2009 2008 2007 2006

All Journal Article Presentation Book

  • [Book] 動物細胞培養の手法と細胞死・増殖不良・細胞変異を防止する技術(第8節[14]唾液腺研究における組織培養・分化誘導系)2014

    • Author(s)
      赤松徹也,姚陳娟,細井和雄
    • Publisher
      ㈱技術情報協会
    • Data Source
      KAKENHI-PROJECT-23592737
  • [Book] 動物細胞培養の手法と細胞死・増殖不良・細胞変異を防止する技術(第9章12節唾液腺研究における組織培養・分化誘導系)2014

    • Author(s)
      赤松徹也,姚陳娟,細井和雄
    • Publisher
      ㈱技術情報協会
    • Data Source
      KAKENHI-PROJECT-23592737
  • [Journal Article] 唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与2013

    • Author(s)
      赤松徹也,姚陳娟,長谷川敬展,吉村弘
    • Journal Title

      J. Oral Biosci.

      Volume: Suppl. Pages: 199-199

    • Data Source
      KAKENHI-PROJECT-23592737
  • [Journal Article] 唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与2013

    • Author(s)
      赤松徹也,姚陳娟,長谷川敬展,吉村弘
    • Journal Title

      J. Oral Biosci

      Volume: Suppl Pages: 199-199

    • Data Source
      KAKENHI-PROJECT-23592737
  • [Journal Article] Involvement of the IL-6/STAT3/Sca-1 system in proliferation of duct cells following duct ligation in the submandibular gland of mice2009

    • Author(s)
      Purwanti, N., Azlina A., Karabasil M.R., Hasegawa T., Yao C., Akamatsu T., Hosoi K.
    • Journal Title

      J Med Invest 56巻

      Pages: 273-276

    • NAID

      120006472137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Journal Article] Aquaglyceroporins in arsenite bio-transportation across gastrointestinal tract membranes2009

    • Author(s)
      Wang, C., Chen G., Jiang J., Qiu L., Li X., Ding S., Hosoi K., Yao C.
    • Journal Title

      J Med Invest 56巻

      Pages: 241-246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Journal Article] Effects of natural point mutation of rat aquaporin 5 expressed in vitro on its capacity of water permeability and membrane trafficking2009

    • Author(s)
      Karabasil, M.R., Murdiastuti K., Purwanti N., Azlina A., Purevjav J., Hasegawa T., Yao C., Akamatsu T., Hosoi K.
    • Journal Title

      J Med Invest 56巻

      Pages: 398-400

    • NAID

      130004822652

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Journal Article] Induction of caiprotectin mRNAs by lipopolysaccharide in the salivary gland of mice2009

    • Author(s)
      Purevjav, J., Hiroshima Y., Azlina A., Hasegawa T., Yao C., Akamatsu T., Nagata T., Hosoi K.
    • Journal Title

      J Med Invest 56巻

      Pages: 343-346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Journal Article] Inhibition and transcriptional silencing of a subtilisin-like proprotein convertase, PACE4/SPC4, reduces the branching morphogenesis of and AQP5 expression in rat embryonic submandibular gland2009

    • Author(s)
      Akamatsu T., Azlina A., Purwanti N., Karabasil M.R., Hasegawa T., Yao C., Hosoi K.
    • Journal Title

      Dev Biol 325巻

      Pages: 434-443

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Journal Article] Salivary gland development: its mediation by a subtilisin-like proprotein convertase, PACE42009

    • Author(s)
      Akamatsu, T., Azlina A., Purevjav J., Hasegawa T., Akamatsu T., Yao C., Hosoi K.
    • Journal Title

      J Med Invest 56巻

      Pages: 241-246

    • NAID

      130004822603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Journal Article] Trafficking of GFP-AQP5 chimeric proteins conferred with unphosphorylated amino acids at their PKA-target motif ((152)SRRTS)2009

    • Author(s)
      Karabasil M.R., Hasegawa T., Azlina A, Purwanti N, Purevjav J, Yao C, Akamatsu T, Hosoi K.
    • Journal Title

      MDCK-II cells 56巻

      Pages: 55-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Journal Article] Down-regulation of submandibular gland AQP5 following parasympathetic denervation in rats2009

    • Author(s)
      Azlina, A., Li X., Purevjav J., Hasegawa T., Yao C., Akamatsu T., Hosoi K.
    • Journal Title

      J Med Invest 56巻

      Pages: 287-289

    • NAID

      130004822614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Journal Article] Trafficking of GFP-AQP5 chimeric proteins conferred with unphosphorylated amino acids at their PKA-target motif(152SRRTS) in MDCK-II cells2009

    • Author(s)
      Karabasil, M.R., T. Hasegawa, A. Azlina, N. Purwanti, J.Purevjav, C. Yao, T. Akamatsu and K. Hosoi
    • Journal Title

      The Journal of Medical Investigation 56(1, 2)

      Pages: 55-63

    • NAID

      130004465167

    • Data Source
      KAKENHI-PROJECT-18390493
  • [Journal Article] Inhibition and transcriptional silencing of a subtilisin-like proprotein convertase, PACE4/SPC4, reduces the branching morphogenesis of and AQP5 expression in rat embryonic submandibular gland2009

    • Author(s)
      Akamatsu, T., A. Azlina, N. Purwanti, M.R. Karabasil, T. Hasegawa, C. Yao, and K. Hosoi
    • Journal Title

      Developmental Biology 325(2)

      Pages: 434-443

    • Data Source
      KAKENHI-PROJECT-18390493
  • [Journal Article] Hypophysectomy and hormonal therapy modulate mK1-immunoreactive duct cells in the mice sublingual glands2008

    • Author(s)
      Kurabuchi S., Gresik E.W., Yao C., Hosoi K.
    • Journal Title

      J Mol Histol 39巻

      Pages: 499-507

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Journal Article] Degradation of submandibular gland AQP5 by parasympathetic denervation of chords tympani and its recovery by cevimeline, an M3 muscarinic receptor agonist2008

    • Author(s)
      Li X., A. Azlina, M.R. Karabasil, N. Purwanti, T. Hasegawa, C. Yao, T. Akamatsu, and K. Hosoi
    • Journal Title

      American Journal of Physiology-Gastrointestinal and Liver Physiology 295(1)

      Pages: 112-123

    • Data Source
      KAKENHI-PROJECT-18390493
  • [Journal Article] Temporospatially regulated expression of subtilisin-like proproteinconvertase PACE4 (SPC4) during development of the rat submandibular gland2007

    • Author(s)
      Akamatsu, T., N. Purwanti, M.R. Karabasil, X. Li, C. Yao, N. Kanamori, and K.Hosoi
    • Journal Title

      Developmental Dynamics 236(1)

      Pages: 314-320

    • Data Source
      KAKENHI-PROJECT-18390493
  • [Journal Article] Protein kinase A-regulated membrane trafficking of a green fluorescent protein-aquaporin 5 chimera in MDCK cells2006

    • Author(s)
      Kosugi-Tanaka, C., X. Li, C. Yao, T. Akamatsu, N. Kanamori, and K. Hosoi
    • Journal Title

      Biochimica et Biophysica Acta, Molecular Cell Research 1763(4)

      Pages: 337-344

    • Data Source
      KAKENHI-PROJECT-18390493
  • [Journal Article] A naturally occurring point mutation in the rat aquaporin 5 gene, influencing its protein production by and secretion of water from salivary glands2006

    • Author(s)
      Murdiastuti, K., N. Purwanti, M.R. Karabasil, X. Li, C. Yao, T. Akamatsu, N. Kanamori, and K. Hosoi
    • Journal Title

      American Journal of Physiology-Gastrointestinal and Liver Physiology 291(6)

      Pages: 1081-1088

    • Data Source
      KAKENHI-PROJECT-18390493
  • [Presentation] 唾液腺再生過程で見られる雌雄差について2016

    • Author(s)
      赤松徹也,姚陳娟,長谷川敬展,吉村弘
    • Organizer
      第58回歯科基礎医学会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-26462814
  • [Presentation] Induced expression of a subtilisin-like proprotein convertase PACE4 in the regeneration model of rat submandibular gland2016

    • Author(s)
      Chenjuan Yao, Tetsuya Akamatsu, Takahiro Hasegawa, Hiroshi Yoshimura
    • Organizer
      The 4th International Symposium on Salivary Glands in Honor of Niels Stensen
    • Place of Presentation
      自然科学研究機構岡崎カンファレンスセンター(愛知県岡崎市)
    • Year and Date
      2016-11-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462814
  • [Presentation] 唾液腺再生モデルにおけるサチライシン様前駆体蛋白質変換酵素PACE4の発現誘導-Part II-2016

    • Author(s)
      嶋谷達哉,嶺岸誠,赤松徹也,姚陳娟,長谷川敬展,吉村弘
    • Organizer
      第58回歯科基礎医学会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-26462814
  • [Presentation] Sexual difference in the regeneration model of the rat submandibular gland2016

    • Author(s)
      Tetsuya Akamatsu, Chenjuan Yao, Takahiro Hasegawa, Hiroshi Yoshimura
    • Organizer
      The 4th International Symposium on Salivary Glands in Honor of Niels Stensen
    • Place of Presentation
      自然科学研究機構岡崎カンファレンスセンター(愛知県岡崎市)
    • Year and Date
      2016-11-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462814
  • [Presentation] 唾液腺再生モデルにおけるサチライシン様前駆体蛋白質変換酵素の発現誘導2014

    • Author(s)
      嶺岸誠,赤松徹也,姚陳娟,長谷川敬展,吉村弘
    • Organizer
      第56回歯科基礎医学会学術大会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-26462814
  • [Presentation] Salivary Gland Development, Differentiation, and Regeneration - Role of Subtilisin-like Proprotein Convertase PACE4/SPC42014

    • Author(s)
      Tetsuya Akamatsu, Chenjuan Yao, Takahiro Hasegawa, and Hiroshi Yoshimura
    • Organizer
      BIT's 1st Annual World Congress of Oral & Dental Medicine
    • Place of Presentation
      Haikou (China)
    • Year and Date
      2014-11-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-26462814
  • [Presentation] 唾液腺再生モデルにおける水チャネルAQP5の発現2014

    • Author(s)
      姚陳娟,赤松徹也,長谷川敬展,吉村弘
    • Organizer
      第56回歯科基礎医学会学術大会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-26462814
  • [Presentation] 唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与2013

    • Author(s)
      赤松徹也,姚陳娟,長谷川敬展,吉村弘
    • Organizer
      第55回歯科基礎医学会
    • Place of Presentation
      岡山コンベンションセンター(岡山県)
    • Data Source
      KAKENHI-PROJECT-23592737
  • [Presentation] 唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与2013

    • Author(s)
      赤松徹也,姚陳娟,長谷川敬展,吉村弘
    • Organizer
      第55回歯科基礎医学会
    • Place of Presentation
      (岡山コンベンションセンター/岡山県)
    • Data Source
      KAKENHI-PROJECT-23592737
  • [Presentation] NF-κB/AP-1の複合体を介した耳下腺AQP5のLPSによるdown-regulation2009

    • Author(s)
      姚陳娟
    • Organizer
      第51回歯科医学会学術大会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Presentation] Potential Down-regulation of Parotid Gland AQP5 by LPS via Cross-coupling of NF-κB/AP12009

    • Author(s)
      姚陳娟
    • Organizer
      The 11th International Symposium on Exocrine Secretion, Tokushima 09 Exocrine Secretion
    • Place of Presentation
      長井記念ホール(徳島)
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Presentation] Potential down-regulation of parotid gland AQP5 by LPS via cross-coupling of NF-κB/AP1, The 11th International Symposium on Exocrine Secretion2009

    • Author(s)
      Chenjuan Yao
    • Organizer
      Tokushima 09 Exocrine Secretion-Mechanism and Disease
    • Place of Presentation
      Tokushima
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Presentation] NF-κB/AP-1複合体を介した耳下腺AQP5のLPSによるdown-regulation2009

    • Author(s)
      姚陳娟
    • Organizer
      第50回歯科基礎医学会学術大会
    • Place of Presentation
      新潟コンベンションセンター(新潟)
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Presentation] 唾液腺における水チャネルAQP5のLPSによるdown-regulationの機構2008

    • Author(s)
      姚陳娟
    • Organizer
      第53回日本唾液腺学会
    • Place of Presentation
      東京
    • Year and Date
      2008-12-06
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Presentation] 唾液腺AQP5のLPSによるdown-regulationの機構2008

    • Author(s)
      姚陳娟
    • Organizer
      第50回歯科医学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Presentation] 唾液腺AQP5のLPSによるdown-regulationの機構2008

    • Author(s)
      姚陳娟
    • Organizer
      第50回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20791353
  • [Presentation] 唾液腺AQP5のLPSによるdown-regulationの機構2008

    • Author(s)
      姚陳娼
    • Organizer
      第50回歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390493
  • [Presentation] 唾液腺における水チャネルAQP5のLPSによるdown-regulationの機構2008

    • Author(s)
      姚 陳娟
    • Organizer
      第53回日本唾液腺学会
    • Place of Presentation
      東京
    • Year and Date
      2008-12-06
    • Data Source
      KAKENHI-PROJECT-18390493
  • [Presentation] 唾液腺AQP5およびAQP1発現のLPSによるdown-regulation2007

    • Author(s)
      姚陳娼
    • Organizer
      第49回歯科基礎医学会学術大会並びに総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-18390493
  • [Presentation] LPS Induces Down-regulation of AQP5 and AQP1 via Nf-xBand MAPK Pathways in the Mouse Parotid Gland2007

    • Author(s)
      Chenjuan Yao
    • Organizer
      The 5th International Conference of Aquaporin
    • Place of Presentation
      Nara,Japan
    • Year and Date
      2007-07-14
    • Data Source
      KAKENHI-PROJECT-18390493
  • [Presentation] LPS Induces Down-regulation of AQP5 and AQP1 via Nf-kB and MAPK Pathways in the Mouse Parotid Gland2007

    • Author(s)
      Chenjuan Yao
    • Organizer
      The 5th International Conference of Aquaporin
    • Place of Presentation
      Nara, Japan
    • Data Source
      KAKENHI-PROJECT-18390493
  • 1.  AKAMATSU Tetsuya (80294700)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 19 results
  • 2.  HOSOI Kazuo (10049413)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 3.  HASEGAWA Takahiro (50447273)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 4.  松本 真司 (20572324)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KANAMORI Norio (90064865)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  吉村 弘 (90288845)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 7.  向井 理恵 (90547978)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  原田 昭和 (30963350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  李 雪飛
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NUNUK Purwanti
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MILEVA Ratko Karabasil
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  AZLINA Ahmad
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 13.  JAVKHLAN Purevjav
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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