Oikawa Daisuke 及川大輔

… Alternative Names

OIKAWA Daisuke 及川大輔

及川大輔オイカワダイスケ

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Researcher Number	20455330
Other IDs
Affiliation (Current)	2025: 大阪公立大学, 大学院医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪公立大学, 大学院医学研究科, 准教授 2020 – 2021: 大阪市立大学, 大学院医学研究科, 准教授 2016 – 2019: 大阪市立大学, 大学院医学研究科, 講師 2014 – 2015: 群馬大学, 生体調節研究所, 助教 2013: 群馬大学, 生体調節研究所, 研究員 2009: 理研, 研究員 2008: The Institute of Physical and Chemical Research, 岩脇独立主幹研究ユニット, ユニット研究員
Review Section/Research Field	Principal Investigator Complex systems / Basic Section 49010:Pathological biochemistry-related / Transformative Research Areas, Section (III) / Biological Sciences / General medical chemistry / Chemical biology / Functional biochemistry Except Principal Investigator Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 51:Brain sciences and related fields
Keywords	Principal Investigator 直鎖状ユビキチン鎖 / ALS / 筋萎縮性側索硬化症 / 阻害剤 / 化合物 / 細胞死 / NF-kB / NDP52 / 炎症性疾患 / 活性酸素 … More / 炎症性腸疾患（IBD） / 炎症応答 / ユビキチン修飾 / マイトファジー / T細胞受容体 / IFN経路 / LRBA / in vivoイメージング / 酸化ストレスレポーター / IL-1β / 炎症シグナル / 試験管内再構築 / 異常タンパク質 / シャペロン / IRE1 / 小胞体 … More Except Principal Investigator 炎症 / ユビキチン / 難治性疾患（認知症・運動機能障害） / コモンクロスシード仮説 / GAPDH凝集 / 創薬 / 脳アミロイドーシス / 自然免疫 / NF-κB / 細胞死 / 化合物探索 / 細胞質封入体 / 疾患修飾薬 / 筋萎縮性側索硬化症 / 神経変性疾患 / 酵素 / タンパク質 Less

複雑化ユビキチン修飾による細胞生死制御の細胞・個体レベルでの解析と病態との関連
- Principal Investigator
  
  徳永文稔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Osaka Metropolitan University
直鎖状ユビキチン鎖によるタンパク質寿命制御機構の解析Principal Investigator
- Principal Investigator
  
  及川大輔
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka Metropolitan University
Therapeutic strategy in brain amyloidosis based on the GAPDH aggregate common cross-seed hypothesis
- Principal Investigator
  
  中嶋秀満
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Osaka Metropolitan University
複合型ユビキチン鎖を標的とした筋萎縮性側索硬化症の病態解明と創薬シーズの開拓
- Principal Investigator
  
  徳永文稔
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 51:Brain sciences and related fields
- Research Institution
  Osaka Metropolitan University
直鎖状ユビキチン代謝を制御する新規ケモテクノロジーによる疾患病態の抑制Principal Investigator
- Principal Investigator
  
  及川大輔
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Study on the Novel Cellular Regulatory Mechanism with LUBAC as a Scaffold and Its Application to Disease TherapyPrincipal Investigator
- Principal Investigator
  
  Oikawa Daisuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
直鎖状ユビキチン鎖が制御する新規オートファジー機構の解明Principal Investigator
- Principal Investigator
  
  及川大輔
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
直鎖状ユビキチン鎖を標的としたケモテクノロジーによる病態解析Principal Investigator
- Principal Investigator
  
  及川大輔
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka City University
Regulation of biological defense responses via linear ubiquitin chains and its contribution to disease onsetPrincipal Investigator
- Principal Investigator
  
  Oikawa Daisuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Osaka City University
Regulation of cellular signal transduction by novel immunological factorPrincipal Investigator
- Principal Investigator
  
  Oikawa Daisuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka City University
  Gunma University
Development of high-sensitive mitochondrial stress reporter for in vivo ROS-damage imagingPrincipal Investigator
- Principal Investigator
  
  OIKAWA Daisuke
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Gunma University
試験管内再構築系による異常タンパク質感知機構の解析Principal Investigator
- Principal Investigator
  
  及川大輔
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  The Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2008 Other

All Journal Article Presentation Patent

[Journal Article] The hypothetical molecular mechanism of the ethnic variations in the manifestation of age-related macular degeneration; focuses on the functions of the most significant susceptibility genes2024
- Author(s)
  Honda Shigeru、Misawa Norihiko、Sato Yusuke、Oikawa Daisuke、Tokunaga Fuminori
- Journal Title
  
  Graefe's Archive for Clinical and Experimental Ophthalmology
  
  Volume: - Issue: 9 Pages: 2799-2811
- DOI
  10.1007/s00417-024-06442-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09773, KAKENHI-PROJECT-21K06873
[Journal Article] LRBA signalosomes activate vasopressin‐induced AQP2 trafficking at recycling endosomes2023
- Author(s)
  Yanagawa Hideki、Hara Yu、Ando Fumiaki、Suzuki Soichiro、Fujiki Tamami、Oikawa Daisuke、Yui Naofumi、Mandai Shintaro、Mori Yutaro、Susa Koichiro、Mori Takayasu、Sohara Eisei、Tokunaga Fuminori、Uchida Shinichi
- Journal Title
  
  The Journal of Physiology
  
  Volume: 601 Issue: 23 Pages: 5437-5451
- DOI
  10.1113/jp285188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21H02933, KAKENHI-PROJECT-23K24346
[Journal Article] Pleiotropic Roles of a KEAP1-Associated Deubiquitinase, OTUD12023
- Author(s)
  Oikawa Daisuke、Shimizu Kouhei、Tokunaga Fuminori
- Journal Title
  
  Antioxidants
  
  Volume: 12 Issue: 2 Pages: 350-350
- DOI
  10.3390/antiox12020350
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-22K07174, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-21H02688, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-22H04922
[Journal Article] Involvement of heterologous ubiquitination including linear ubiquitination in Alzheimer’s disease and amyotrophic lateral sclerosis2023
- Author(s)
  Sato Yusuke、Terawaki Seigo、Oikawa Daisuke、Shimizu Kouhei、Okina Yoshinori、Ito Hidefumi、Tokunaga Fuminori
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 10 Pages: 1089213-1089213
- DOI
  10.3389/fmolb.2023.1089213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-22K07174, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-21H02418, KAKENHI-PROJECT-21H02688, KAKENHI-PUBLICLY-21H00283, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-22H04922
[Journal Article] Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased survival of mice following viral infection2023
- Author(s)
  Fukushi Masaya、Ohsawa Ryosuke、Okinaka Yasushi、Oikawa Daisuke、Kiyono Tohru、Moriwaki Masaya、Irie Takashi、Oda Kosuke、Kamei Yasuhiro、Tokunaga Fuminori、Sotomaru Yusuke、Maruyama Hirofumi、Kawakami Hideshi、Sakaguchi Takemasa
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 6 Pages: e0287545-e0287545
- DOI
  10.1371/journal.pone.0287545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H05702, KAKENHI-PROJECT-21H04818, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-23K26510, KAKENHI-PROJECT-23K27518
[Journal Article] OTUD1 deubiquitinase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways2022
- Author(s)
  Oikawa Daisuke、Gi Min、Kosako Hidetaka、Shimizu Kouhei、Takahashi Hirotaka、Shiota Masayuki、Hosomi Shuhei、Komakura Keidai、Wanibuchi Hideki、Tsuruta Daisuke、Sawasaki Tatsuya、Tokunaga Fuminori
- Journal Title
  
  Cell Death & Disease
  
  Volume: 13 Issue: 8 Pages: 694-694
- DOI
  10.1038/s41419-022-05145-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-22K07174, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H02951, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-20K06611, KAKENHI-PROJECT-21K19230, KAKENHI-PUBLICLY-21H00287, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-20K10431
[Journal Article] Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species2022
- Author(s)
  Hoang Dinh Viet、Thuy Le Thi Thanh、Hai Hoang、Hieu Vu Ngoc、Kimura Kenjiro、Oikawa Daisuke、Ikura Yoshihiro、Dat Ninh Quoc、Hoang Truong Huu、Sato-Matsubara Misako、Dong Minh Phuong、Hanh Ngo Vinh、Uchida-Kobayashi Sawako、Tokunaga Fuminori、Kubo Shoji、Ohtani Naoko、Yoshizato Katsutoshi、Kawada Norifumi
- Journal Title
  
  Oncogenesis
  
  Volume: 11 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41389-022-00389-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K07921, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21H03369, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-23K24322
[Journal Article] LRBA is essential for urinary concentration and body water homeostasis2022
- Author(s)
  Hara Y, Ando F, Oikawa D, Ichimura K, Yanagawa H, Sakamaki Y, Nanamatsu A, Fujiki T, Mori S, Suzuki S, Yui N, Mandai S, Susa K, Mori T, Sohara E, Rai T, Takahashi M, Sasaki S, Kagechika H, Tokunaga F, Uchida S.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 30
- DOI
  10.1073/pnas.2202125119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K08249, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21H02933, KAKENHI-PROJECT-18K08233, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-23K24346
[Journal Article] Suppression of Linear Ubiquitination Ameliorates Cytoplasmic Aggregation of Truncated TDP-432022
- Author(s)
  Zhang Qiang、Terawaki Seigo、Oikawa Daisuke、Okina Yoshinori、Usuki Yoshinosuke、Ito Hidefumi、Tokunaga Fuminori
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 15 Pages: 2398-2398
- DOI
  10.3390/cells11152398
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02688, KAKENHI-PUBLICLY-21H00291
[Journal Article] Identification and molecular analysis of <i>RNF31</i> Q622H germline polymorphism2022
- Author(s)
  Nakazawa Seshiru、Mamiya Ryo、Kawabata?Iwakawa Reika、Oikawa Daisuke、Kaira Kyoichi、Tokunaga Fuminori、Nobusawa Sumihito、Sato Yusuke、Sasaki Atsushi、Yajima Toshiki、Shirabe Ken
- Journal Title
  
  Oncology Letters
  
  Volume: 24 Issue: 5 Pages: 394-394
- DOI
  10.3892/ol.2022.13514
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02418, KAKENHI-PROJECT-21H02688, KAKENHI-PUBLICLY-21H00283, KAKENHI-PUBLICLY-21H00291
[Journal Article] Spinocerebellar ataxia type 17-digenic TBP/STUB1 disease: neuropathologic features of an autopsied patient2022
- Author(s)
  Saito Rie、Tada Yui、Oikawa Daisuke、Sato Yusuke、Seto Makiko、Satoh Akira、Kume Kodai、Ueki Nozomi、Nakashima Masahiro、Hayashi Shintaro、Toyoshima Yasuko、Tokunaga Fuminori、Kawakami Hideshi、Kakita Akiyoshi
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 10 Issue: 1 Pages: 177-177
- DOI
  10.1186/s40478-022-01486-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04818, KAKENHI-PROJECT-21H02418, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-20K07424, KAKENHI-PROJECT-20K08886, KAKENHI-PUBLICLY-21H00283, KAKENHI-PUBLICLY-21H00291
[Journal Article] Cloaking the ACE2 receptor with salivary cationic proteins inhibits SARS-CoV-2 entry2022
- Author(s)
  Yoshizato Katsutoshi、Taira Toshio、Sato-Matsubara Misako、Sekiguchi Shizuko、Yabunaka Yoriko、Kira Yukimi、Ohashi Tetsu、Daikoku Atsuko、Ofusa Ken、Kadono Chiho、Oikawa Daisuke、Matsubara Tsutomu、Nakagama Yu、Kido Yasutoshi、Tokunaga Fuminori、Ikeda Kazuo、Kaneko Akira、Kawada Norifumi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 172 Issue: 4 Pages: 205-216
- DOI
  10.1093/jb/mvac054
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02688, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-23K21359
[Journal Article] Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion.2022
- Author(s)
  Hieu VN, Thuy LTT, Hai H, Dat NQ, Hoang DV, Hanh NV, Phuong DM, Hoang TH, Sawai H, Shiro Y, Sato-Matsubara M, Oikawa D, Tokunaga F, Yoshizato K, Kawada N.
- Journal Title
  
  Redox Biol.
  
  Volume: 52 Pages: 102286-102286
- DOI
  10.1016/j.redox.2022.102286
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-21K05281, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H00926, KAKENHI-PROJECT-21H02688, KAKENHI-PLANNED-19H05761, KAKENHI-PROJECT-23K24322
[Journal Article] Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease2021
- Author(s)
  Kuriyama Yuko、Shimizu Akira、Kanai Saki、Oikawa Daisuke、Motegi Sei-ichiro、Tokunaga Fuminori、Ishikawa Osamu
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 23146-23146
- DOI
  10.1038/s41598-021-02522-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08766, KAKENHI-PROJECT-21K20753, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-16H06276
[Journal Article] Crosstalk Between NDP52 and LUBAC in Innate Immune Responses, Cell Death, and Xenophagy.2021
- Author(s)
  Miyashita H, Oikawa D, Terawaki S, Kabata D, Shintani A, Tokunaga F.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 635475-635475
- DOI
  10.3389/fimmu.2021.635475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06937, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-16H06276
[Journal Article] 6His-tagged Recombinant Human Cytoglobin Deactivates Hepatic Stellate Cells and Inhibits Liver Fibrosis by Scavenging Reactive Oxygen Species2021
- Author(s)
  Ninh Quoc Dat, Le Thi Thanh Thuy, Vu Ngoc Hieu, Fuminori Tokunaga, Massimo Pinzani, and Norifumi Kawada
- Journal Title
  
  Hepatology
  
  Volume: 0-0 Issue: 6 Pages: 0-0
- DOI
  10.1002/hep.31752
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08428, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-18K07952, KAKENHI-PROJECT-19K22541, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-19H03641, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-16H06276
[Journal Article] Th2 cells and macrophages cooperatively induce allergic inflammation through histamine signaling2021
- Author(s)
  Iwasaki N, Terawaki S, Shimizu K, Oikawa D, Sakamoto H, Sunami K, Tokunaga F.
- Journal Title
  
  Plos One
  
  Volume: - Issue: 3 Pages: e0248158-e0248158
- DOI
  10.1371/journal.pone.0248158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17912, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06937, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-20K16146, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-16H06276
[Journal Article] The synchronized gene expression of retrotransposons and type I interferon in dermatomyositis.2021
- Author(s)
  Kuriyama Y, Shimizu A, Kanai S, Oikawa D, Tokunaga F, Tsukagoshi H, Ishikawa O.
- Journal Title
  
  Journal of American Academy of Dermatology
  
  Volume: 84 Issue: 4 Pages: 1103-1105
- DOI
  10.1016/j.jaad.2020.05.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K08766, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-21H02688
[Journal Article] Th2 cell-derived histamine is involved in nasal Th2 infiltration in mice2021
- Author(s)
  Iwasaki N, Terawaki S, Shimizu K, Oikawa D, Sakamoto H, Sunami K, Tokunaga F.
- Journal Title
  
  Inflammation Research
  
  Volume: In press Issue: 5 Pages: 539-541
- DOI
  10.1007/s00011-021-01458-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18K06937, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-19K17912, KAKENHI-PROJECT-20K16146, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PUBLICLY-20H05337, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-16H06276
[Journal Article] Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling2020
- Author(s)
  Yamanaka Satoshi、Sato Yusuke、Oikawa Daisuke、Goto Eiji、Fukai Shuya、Tokunaga Fuminori、Takahashi Hirotaka、Sawasaki Tatsuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 524 Issue: 1 Pages: 1-7
- DOI
  10.1016/j.bbrc.2019.12.049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PLANNED-16H06575, KAKENHI-PLANNED-16H06579, KAKENHI-PLANNED-18H05501, KAKENHI-PUBLICLY-19H05292, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-17K07261, KAKENHI-PROJECT-16H06276
[Journal Article] Cellular and Mathematical Analyses of LUBAC Involvement in T Cell Receptor-Mediated NF-κB Activation Pathway2020
- Author(s)
  D.Oikawa, N.Hatanaka, T.Suzuki, F.Tokunaga
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 601926-601926
- DOI
  10.3389/fimmu.2020.601926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06576, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H05468, KAKENHI-PUBLICLY-19H05296
[Journal Article] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.2020
- Author(s)
  Oikawa D, Sato Y, Ohtake F, Komakura K, Hanada K, Sugawara K, Terawaki S, Mizukami Y, Phuong HT, Iio K, Obika S, Fukushi M, Irie T, Tsuruta D, Sakamoto S, Tanaka K, Saeki Y, Fukai S, Tokunaga F.
- Journal Title
  
  Communications Biology
  
  Volume: -
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Journal Article] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.2020
- Author(s)
  Oikawa D, Sato Y, Ohtake F, Komakura K, Hanada K, Sugawara K, Terawaki S, Mizukami Y, Phuong HT, Iio K, Obika S, Fukushi M, Irie T, Tsuruta D, Sakamoto S, Tanaka K, Saeki Y, Fukai S, Tokunaga F.
- Journal Title
  
  Communications Biology
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-18K06967
[Journal Article] Linear ubiquitin code: Its writer, erasers, decoders, inhibitors, and implications in disorders.2020
- Author(s)
  Oikawa D, Sato Y, Ito H, and Tokunaga F.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 9 Pages: 3381-3381
- DOI
  10.3390/ijms21093381
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-20H05337, KAKENHI-PROJECT-18H02743, KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-19H05296
[Journal Article] Involvement of linear ubiquitination in neurodegenerative diseases and development of LUBAC inhibitors2020
- Author(s)
  及川大輔、伊東秀文、徳永文稔
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 1 Pages: 28-34
- DOI
  10.14952/SEIKAGAKU.2020.920028
- ISSN
  0037-1017
- Year and Date
  2020-02-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06967, KAKENHI-PROJECT-19K22541, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-19H05296, KAKENHI-PROJECT-18H02619
[Journal Article] Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling2019
- Author(s)
  Katsuya Ken、Oikawa Daisuke、Iio Kiyosei、Obika Shingo、Hori Yuji、Urashima Toshiki、Ayukawa Kumiko、Tokunaga Fuminori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 509 Issue: 3 Pages: 700-706
- DOI
  10.1016/j.bbrc.2018.12.164
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06967
[Journal Article] High-Throughput Screening for Linear Ubiquitin Chain Assembly Complex (LUBAC) Selective Inhibitors Using Homogenous Time-Resolved Fluorescence (HTRF)-Based Assay System2018
- Author(s)
  Katsuya Ken、Hori Yuji、Oikawa Daisuke、Yamamoto Tomohisa、Umetani Kayo、Urashima Toshiki、Kinoshita Tomomi、Ayukawa Kumiko、Tokunaga Fuminori、Tamaru Masahiro
- Journal Title
  
  SLAS DISCOVERY: Advancing Life Sciences R&D
  
  Volume: 23 Issue: 10 Pages: 1018-1029
- DOI
  10.1177/2472555218793066
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06967
[Journal Article] Generalized verrucosis caused by various human papillomavirus in a patient with GATA2 deficiency.2018
- Author(s)
  Kuriyama Y, Hattori M, Mitsui T, Nakano H, Tokunaga F, Oikawa D, Ishikawa O, Shimizu A.
- Journal Title
  
  J Dermatol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08259
[Journal Article] Generation of Rat Monoclonal Antibodies Against a Deubiquitinase, Ovarian Tumor Domain-Containing Protein 12018
- Author(s)
  Oikawa Daisuke、Shiota Masayuki、Goto Eiji、Komakura Keidai、Wanibuchi Hideki、Tokunaga Fuminori
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 37 Issue: 4 Pages: 180-184
- DOI
  10.1089/mab.2018.0023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09162, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06967
[Journal Article] Generation of Rat Monoclonal Antibodies Specific for DZIP3.2018
- Author(s)
  Oikawa D, Shiota M, Tokunaga F, Wanibuchi H.
- Journal Title
  
  Monoclon Antib Immunodiagn Immunother.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08259
[Journal Article] In-frame Val216-Ser217 deletion of KIT in mild piebaldism causes aberrant secretion and SCF response.2018
- Author(s)
  Hattori M, Ishikawa O, Oikawa D, Amano H, Yasuda M, Kaira K, Ishida-Yamamoto A, Nakano H, Sawamura D, Terawaki S, Wakamatsu K, Tokunaga F, Shimizu A.
- Journal Title
  
  J Dermatol Sci.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08259
[Journal Article] In-frame Val 216 -Ser 217 deletion of KIT in mild piebaldism causes aberrant secretion and SCF response2018
- Author(s)
  Hattori Mai、Ishikawa Osamu、Oikawa Daisuke、Amano Hiroo、Yasuda Masahito、Kaira Kyoichi、Ishida-Yamamoto Akemi、Nakano Hajime、Sawamura Daisuke、Terawaki Shin-ichi、Wakamatsu Kaori、Tokunaga Fuminori、Shimizu Akira
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 91 Issue: 1 Pages: 35-42
- DOI
  10.1016/j.jdermsci.2018.03.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07301, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16K07262, KAKENHI-PROJECT-18K06967
[Journal Article] Generation of Rat Monoclonal Antibodies Specific for DZIP32018
- Author(s)
  Oikawa Daisuke、Shiota Masayuki、Tokunaga Fuminori、Wanibuchi Hideki
- Journal Title
  
  Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
  
  Volume: 37 Issue: 3 Pages: 153-157
- DOI
  10.1089/mab.2018.0005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09162, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06967
[Journal Article] Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 12018
- Author(s)
  Kato Kazuki、Nishimasu Hiroshi、Oikawa Daisuke、Hirano Seiichi、Hirano Hisato、Kasuya Go、Ishitani Ryuichiro、Tokunaga Fuminori、Nureki Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 4424-4424
- DOI
  10.1038/s41467-018-06922-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06574, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-17H05592, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H02384, KAKENHI-PROJECT-18K06967
[Journal Article] ER stress in the pathogenesis of pretibial dystrophic epidermolysis bullosa.2017
- Author(s)
  Hattori M, Shimuzu A, Oikawa D, Kamei K, Kaira K, Ishida-Yamamoto A, Nakano H, Sawamura D, Tokunaga F, and Ishikawa O.
- Journal Title
  
  Br. J. Dermatol.
  
  Volume: 印刷中 Issue: 4 Pages: e92-e93
- DOI
  10.1111/bjd.15342
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-16H01192, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-16K15210, KAKENHI-PROJECT-15K08259, KAKENHI-PROJECT-15K09739
[Journal Article] Structural and functional analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide.2016
- Author(s)
  Omura H, Oikawa D, Nakane T, Kato M, Ishii R, Ishitani R, Tokunaga F, and Nureki O.
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 34756-34756
- DOI
  10.1038/srep34756
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-16H01192, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-15K08259, KAKENHI-PROJECT-16K15210
[Journal Article] Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.2016
- Author(s)
  Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, and Tokunaga F.
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Issue: 1 Pages: 12547-12547
- DOI
  10.1038/ncomms12547
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-16H01192, KAKENHI-PLANNED-16H06575, KAKENHI-PLANNED-16H06579, KAKENHI-PLANNED-24112002, KAKENHI-PROJECT-15H04270, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-15K18468, KAKENHI-PROJECT-15K08259, KAKENHI-PROJECT-16K15210, KAKENHI-PROJECT-16K18383
[Journal Article] Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.2015
- Author(s)
  Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa T, Kataoka Y, Yamamura K.
- Journal Title
  
  Scientific Reports.
  
  Volume: 5 Issue: 1 Pages: 17205-17205
- DOI
  10.1038/srep17205
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08259, KAKENHI-PUBLICLY-15H00905, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25460399
[Journal Article] Membrane lipid saturation activates IRE1α without inducing clustering.2013
- Author(s)
  Kitai Y, Ariyama H, Kono N, Oikawa D, Iwawaki T, Arai H.
- Journal Title
  
  Genes Cells.
  
  Volume: 18 Pages: 798-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870118
[Journal Article] Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins.2013
- Author(s)
  Oikawa D, Iwawaki T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 433 Pages: 426-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870118
[Journal Article] The role of the unfolded protein response in diabetes mellitus.2013
- Author(s)
  Iwawaki T, Oikawa D.
- Journal Title
  
  Semin Immunopathol.
  
  Volume: 35 Pages: 333-350
- Data Source
  KAKENHI-PROJECT-25870118
[Journal Article] 生きているマウスで酸化ストレスを見えるように2013
- Author(s)
  及川大輔，岩脇隆夫
- Journal Title
  
  化学と生物
  
  Volume: 51 Pages: 361-363
- Data Source
  KAKENHI-PROJECT-25870118
[Patent] 炎症レポーターシステム2014
- Inventor(s)
  岩脇隆夫、及川大輔、石川智夫
- Industrial Property Rights Holder
  岩脇隆夫、及川大輔、石川智夫
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-31
- Overseas
- Data Source
  KAKENHI-PROJECT-25870118
[Presentation] 新規LUBAC結合E3によるTNF誘導性細胞死の多面的制御2023
- Author(s)
  清水康平、魏民、及川大輔、Tran Thi Thuy Linh、小迫英尊、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] BEACHドメイン含有タンパク質（BDCP）の新機能：RNAウイルス誘導性細胞死の制御と非アルコール性脂肪性肝疾患への寄与2023
- Author(s)
  及川大輔、翁良徳、魏民、塩田正之、福士雅也、入江崇、堀居拓郎、畑田出穂、坂口剛正、河田則文、徳永文稔
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] 新規LUBAC結合E3による複合型ユビキチン鎖形成を介したネクロプトーシスの制御2023
- Author(s)
  清水康平、魏民、及川大輔、Tran Thi Thuy Linh、小迫英尊、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第31回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] LUBAC阻害剤およびLUBAC協働性E3による細胞機能制御2023
- Author(s)
  徳永文稔, 及川大輔, 清水康平, 畑中由香里
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] BEACHドメイン含有タンパク質（BDCP）の新機能：RNAウイルス誘導性細胞死の制御と非アルコール性脂肪性肝疾患への寄与2023
- Author(s)
  及川大輔、翁良徳、魏民、塩田正之、福士雅也、入江崇、堀居拓郎、畑田出穂、坂口剛正、河田則文、徳永文稔
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] LRBAはRNAウイルス誘導性細胞死（RIPA）を制御する2023
- Author(s)
  及川大輔、魏民、塩田正之、福士雅也、入江崇、堀居拓郎、畑田出穂、坂口剛正、徳永文稔
- Organizer
  第31回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] Heat shock protein 70-dependent regulation of cell adhesion and migration2023
- Author(s)
  Shiota M, Min G, Oikawa D, Tokunaga F.
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] LRBAは尿細管における塩および水の再吸収を制御する2023
- Author(s)
  柳川英輝、安藤史顕、及川大輔、七松東、原悠、鈴木聡一郎、藤木珠美、萬代新太郎、森雄太郎、森崇寧、須佐紘一郎、蘇原映誠、徳永文稔、内田信一
- Organizer
  第66回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] OTUD1 plays an important role in inflammatory response through regulation of programmed cell death2023
- Author(s)
  Tran Thi Thuy Linh、Oikawa D, Shimizu K, Okina Y, Tokunaga F
- Organizer
  第17回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] LRBAによるRIG-I様受容体シグナル制御と非アルコール性脂肪性肝疾患への寄与2023
- Author(s)
  及川大輔、翁良徳、魏民、塩田正之、福士雅也、入江崇、堀居拓郎、畑田出穂、坂口剛正、河田則文、徳永文稔
- Organizer
  第17回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] ウイルスRNA受容体MDA5を介したIFN産生シグナルを制御する脱ユビキチン化酵素の機能解析2023
- Author(s)
  坂口詩穏、高橋宏隆、及川大輔、徳永文稔、西野耕平、小迫英尊、澤崎達
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] ウイルスRNA受容体MDA5を介したIFN産生シグナルを制御する脱ユビキチン化酵素の機能解析2023
- Author(s)
  坂口詩穏, 高橋宏隆, 及川大輔, 徳永文稔, 西野耕平3 小迫英尊, 澤崎達也
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] LRBAはRNAウイルス誘導性細胞死（RIPA）を制御する2023
- Author(s)
  及川大輔、魏民、塩田正之、福士雅也、入江崇、堀居拓郎、畑田出穂、坂口剛正、徳永文稔
- Organizer
  第31回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] Gordon Holmes syndrome and SCA17-DI: pathologic features of 2 patients with Huntington-like disorder2023
- Author(s)
  Saito R, Tada Y, Oikawa D, Sato Y, Iwanaga K, Satoh A, Seto M, Kume K, Ueki N, Nakashima M, Hayashi S, Toyoshima Y, Tokunaga F, Kawakami H, Kakita A.
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] Gordon Holmes syndrome and SCA17-DI: pathologic features of 2 patients with Huntington-like disorder2023
- Author(s)
  Saito R, Tada Y, Oikawa D, Sato Y, Iwanaga K, Satoh A, Seto M, Kume K, Ueki N, Nakashima M, Hayashi S, Toyoshima Y, Tokunaga F, Kawakami H, Kakita A.
- Organizer
  第64回日本神経病理学会総会学術研究会/第66回日本神経化学会大会合同大会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] Gordon Holmes syndrome and SCA17-DI: pathologic features of 2 patients with Huntington-like disorder2023
- Author(s)
  aito R, Tada Y, Oikawa D, Sato Y, Iwanaga K, Satoh A, Seto M, Kume K, Ueki N, Nakashima M, Hayashi S, Toyoshima Y, Tokunaga F, Kawakami H, Kakita A
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] LRBAは尿細管における塩および水の再吸収を制御する2023
- Author(s)
  柳川英輝、安藤史顕、及川大輔、七松東、原悠、鈴木聡一郎、藤木珠美、萬代新太郎、森雄太郎、森崇寧、須佐紘一郎、蘇原映誠、徳永文稔、内田信一
- Organizer
  第66回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 新規LUBAC結合タンパク質によるネクロプトーシス制御機構2023
- Author(s)
  清水康平、魏民、及川大輔、Tran Thi Thuy Linh、小迫英尊、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第69回生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] 直鎖状ユビキチン鎖生成酵素（LUBAC）阻害剤のALSモデルマウスへの影響2023
- Author(s)
  畑中由香里、及川大輔、翁良徳、臼杵克之助、徳永文稔
- Organizer
  第17回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] LUBAC阻害剤およびLUBAC協働性E3による細胞機能制御2023
- Author(s)
  徳永文稔、及川大輔、清水康平、畑中由香里
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 直鎖状ユビキチン鎖生成酵素（LUBAC）阻害剤のALSモデルマウスへの影響2023
- Author(s)
  畑中由香里、及川大輔、翁良徳、臼杵克之助、徳永文稔
- Organizer
  第17回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] LUBAC and its associated ubiquitin ligase generate heterotypic ubiquitin chains to inhibit necroptosis2023
- Author(s)
  Shimizu K, Gi M, Oikawa D, Linh TTT, Kosako H, Takahashi H, Sawasaki T, Tokunaga F
- Organizer
  The 3rd Japan and Australia Meeting on Cell Death
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] Heat shock protein 70-dependent regulation of cell adhesion and migration2023
- Author(s)
  Shiota M, Min G, Oikawa D, Tokunaga F
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] 新規LUBAC結合E3によるTNF誘導性細胞死の多面的制御2023
- Author(s)
  清水康平, 魏民, 及川大輔, Tran Thi Thuy Linh, 小迫英尊, 高橋宏隆, 澤崎達也, 徳永文稔
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] LRBAによるRIG-I様受容体シグナル制御と非アルコール性脂肪性肝疾患への寄与2023
- Author(s)
  及川大輔、翁良徳、魏民、塩田正之、福士雅也、入江崇、堀居拓郎、畑田出穂、坂口剛正、河田則文、徳永文稔
- Organizer
  第17回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] 新規LUBAC結合タンパク質によるネクロプトーシス制御機構2023
- Author(s)
  清水康平、魏民、及川大輔、Tran Thi Thuy Linh、小迫英尊、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第69回生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 新規LUBAC結合E3による複合型ユビキチン鎖形成を介したネクロプトーシスの制御2023
- Author(s)
  清水康平、魏民、及川大輔、Tran Thi Thuy Linh、小迫英尊、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第31回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] OTUD1 plays an important role in inflammatory response through regulation of programmed cell death2023
- Author(s)
  Tran Thi Thuy Linh, Oikawa D, Shimizu K, Okina Y, Tokunaga F
- Organizer
  第17回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] タンパク質アレイ技術を基盤とした脱ユビキチン化酵素の機能解析2022
- Author(s)
  高橋宏隆、檜垣佳奈、山中聡士、佐藤裕介、平野港、好井健太朗、髙谷大輔、本間光貴、及川大輔、徳永文稔、澤崎達也
- Organizer
  第27回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] The inhibition of LUBAC mitigates amyotrophic lateral sclerosis-associated TDP-43 aggregation2022
- Author(s)
  Zhang Q, Terawaki S, Oikawa D, Okina Y, Usuki Y, Tokunaga F.
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] OTUD1-KEAP1による炎症、酸化ストレス、細胞死制御と炎症性疾患抑制2022
- Author(s)
  及川大輔、魏民、清水康平、小迫英尊、塩田正之、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] LRBA は尿濃縮と体液恒常性維持に必須の分子である2022
- Author(s)
  原悠、安藤史顕、及川大輔、市村浩一郎、藤木珠美、萬代新太郎、森崇寧、須佐紘一郎、蘇原映誠、頼建光、徳永文稔、内田信一
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] ウイルスRNA受容体MDA5を介したIFNシグナルを制御する脱ユビキチン化酵素の同定と機能解析2022
- Author(s)
  坂口詩穏、髙橋宏隆、西耕平、小迫英尊、及川大輔、徳永文稔、澤崎達也
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] LRBA is essential for urinary concentration and body water homeostasis2022
- Author(s)
  Hara Y, Ando F, Oikawa D, Ichimura K, Fujiki T, Mandai S, Mori T, Susa K, Sohara E, Rai T, Tokunaga F, Uchida S.
- Organizer
  ASN kidney week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 新規LUBAC結合タンパク質による細胞死制御機構の解析2022
- Author(s)
  清水康平、魏民、Tran Thi Thuy Linh、及川大輔、小迫英尊、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] 直鎖状ユビキチン鎖生成酵素を標的とした阻害剤開発と疾患治療薬としての基礎検討2022
- Author(s)
  及川大輔、張強、寺脇正剛、翁良、臼杵克之助、徳永文稔
- Organizer
  第74回日本細胞生物学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] ウイルスRNA受容体MDA5を介したIFNシグナルを制御する脱ユビキチン化酵素の同定と機能解析2022
- Author(s)
  坂口詩穏、髙橋宏隆、西耕平、小迫英尊、及川大輔、徳永文稔、澤崎達也
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 脱ユビキチン化酵素 OTUD1による炎症・細胞死制御と病態2022
- Author(s)
  及川大輔、魏民、清水康平、小迫英尊、塩田正之、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第27回日本病態プロテアーゼ学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] タンパク質アレイ技術を基盤とした脱ユビキチン化酵素の機能解析2022
- Author(s)
  高橋宏隆、檜垣佳奈、山中聡士、佐藤裕介、平野港、好井健太朗、髙谷大輔、本間光貴、及川大輔、徳永文稔、澤崎達也
- Organizer
  第27回日本病態プロテアーゼ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 脱ユビキチン化酵素 OTUD1による炎症・細胞死制御と病態2022
- Author(s)
  及川大輔、魏民、清水康平、小迫英尊、塩田正之、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第27回日本病態プロテアーゼ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] OTUD1-KEAP1による炎症、酸化ストレス、細胞死制御と炎症性疾患抑制2022
- Author(s)
  及川大輔、魏民、清水康平、小迫英尊、塩田正之、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第95回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] LRBA is essential for urinary concentration and body water homeostasis2022
- Author(s)
  Hara Y, Ando F, Oikawa D, Ichimura K, Fujiki T, Mandai S, Mori T, Susa K, Sohara E, Rai T, Tokunaga F, Uchida S.
- Organizer
  ASN kidney week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 形質膜におけるCFTR脱ユビキチン化の促進はCF治療剤の効果を増強する2022
- Author(s)
  小林祐斗、森島良貴、辻尚樹、福田亮介、及川大輔、徳永文稔、沖米田司
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] The inhibition of LUBAC mitigates amyotrophic lateral sclerosis-associated TDP-43 aggregation2022
- Author(s)
  Zhang Q, Terawaki S, Oikawa D, Okina Y, Usuki Y, Tokunaga F.
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 新規LUBAC結合タンパク質による細胞死制御機構の解析2022
- Author(s)
  清水康平、魏民、Tran Thi Thuy Linh、及川大輔、小迫英尊、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] LRBA is essential for urinary concentration and body water homeostasis2022
- Author(s)
  Hara Y、Ando F、Oikawa D、Ichimura K、Yanagawa H、Sakamaki Y、Nanamatsu A、Fujiki T、Mori S、Suzuki S、Yui N、Mandai S、Susa K、Mori T、Sohara E、Rai T、Takahashi M、Sasaki S、Kagechika H、Tokunaga F、Uchida S
- Organizer
  ASN kidney week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] OTUD1-KEAP1による炎症、酸化ストレス、細胞死制御と炎症性疾患抑制2022
- Author(s)
  及川大輔、魏民、清水康平、小迫英尊、塩田正之、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第95回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 直鎖状ユビキチン鎖を標的としたTDP-43凝集体抑制手法の開発2022
- Author(s)
  及川大輔
- Organizer
  第15回小胞体ストレス応答研究会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] ウイルスRNA受容体MDA5を介したIFNシグナルを制御する脱ユビキチン化酵素の同定と機能解析2022
- Author(s)
  坂口詩穏、髙橋宏隆、西耕平、小迫英尊、及川大輔、徳永文稔、澤崎達也
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 直鎖状ユビキチン鎖生成酵素を標的とした阻害剤開発と疾患治療薬としての基礎検討2022
- Author(s)
  及川大輔、張強、寺脇正剛、翁良、臼杵克之助、徳永文稔
- Organizer
  第74回日本細胞生物学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 新規LUBAC結合タンパク質による細胞死制御機構の解析2022
- Author(s)
  清水康平、魏民、Tran Thi Thuy Linh、及川大輔、小迫英尊、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 細胞内ウイルス受容体MDA5を制御するDUBの探索と機能解析2022
- Author(s)
  高橋宏隆、坂口詩穏、西野耕平、小迫英尊、及川大輔、徳永文稔、澤崎達也
- Organizer
  第95回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 形質膜におけるCFTR脱ユビキチン化の促進はCF治療剤の効果を増強する2022
- Author(s)
  小林祐斗、森島良貴、辻尚樹、福田亮介、及川大輔、徳永文稔、沖米田司
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 直鎖状ユビキチン鎖を標的としたTDP-43凝集体抑制手法の開発2022
- Author(s)
  及川大輔
- Organizer
  第15回小胞体ストレス応答研究会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 脱ユビキチン化酵素 OTUD1による炎症・細胞死制御と病態2022
- Author(s)
  及川大輔、魏民、清水康平、小迫英尊、塩田正之、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第27回日本病態プロテアーゼ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] LRBAは尿濃縮と体液恒常性維持に必須の分子である2022
- Author(s)
  原悠、安藤史顕、及川大輔、市村浩一郎、藤木珠美、萬代新太郎、森崇寧、須佐紘一郎、蘇原映誠、頼建光、徳永文稔、内田信一
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] タンパク質アレイ技術を基盤とした脱ユビキチン化酵素の機能解析2022
- Author(s)
  高橋宏隆、檜垣佳奈、山中聡士、佐藤裕介、平野港、好井健太朗、髙谷大輔、本間光貴、及川大輔、徳永文稔、澤崎達也
- Organizer
  第27回日本病態プロテアーゼ学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 細胞内ウイルス受容体MDA5を制御するDUBの探索と機能解析2022
- Author(s)
  高橋宏隆、坂口詩穏、西野耕平、小迫英尊、及川大輔、徳永文稔、澤崎達也
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] The inhibition of LUBAC mitigates amyotrophic lateral sclerosis-associated TDP-43 aggregation2022
- Author(s)
  Zhang Q, Terawaki S, Oikawa D, Okina Y, Usuki Y, Tokunaga F.
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] LRBA は尿濃縮と体液恒常性維持に必須の分子である2022
- Author(s)
  原悠、安藤史顕、及川大輔、市村浩一郎、藤木珠美、萬代新太郎、森崇寧、須佐紘一郎、蘇原映誠、頼建光、徳永文稔、内田信一
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 細胞内ウイルス受容体MDA5を制御するDUBの探索と機能解析2022
- Author(s)
  高橋宏隆、坂口詩穏、西野耕平、小迫英尊、及川大輔、徳永文稔、澤崎達也
- Organizer
  第95回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 直鎖状ユビキチン鎖生成酵素を標的とした阻害剤開発と疾患治療薬としての基礎検討2022
- Author(s)
  及川大輔、張強、寺脇正剛、翁良、臼杵克之助、徳永文稔
- Organizer
  第74回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K18385
[Presentation] 形質膜におけるCFTR脱ユビキチン化の促進はCF治療剤の効果を増強する2022
- Author(s)
  小林祐斗、森島良貴、辻尚樹、福田亮介、及川大輔、徳永文稔、沖米田司
- Organizer
  第95回日本生化学会大会名古屋国際会場
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] Identification of OTUD1 deubiquitinase as a regulator for innate immune responses, cell death, and inflammatory bowel disease2021
- Author(s)
  Oikawa D, Gi M, Kosako H, Shimizu K, Shiota M, Takahashi H, Sawasaki T, Tokunaga F.
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] Identification of OTUD1 deubiquitinase as a regulator for innate immune responses, cell death, and inflammatory bowel disease2021
- Author(s)
  Oikawa D, Gi M, Kosako H, Shimizu K, Shiota M, Takahashi H, Sawasaki T, Tokunaga F.
- Organizer
  第94回日本生化学会大
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] Identification of OTUD1 deubiquitinase as a regulator for innate immune responses, cell death, and inflammatory bowel disease2021
- Author(s)
  Oikawa D, Gi M, Kosako H, Shimizu K, Shiota M, Takahashi H, Sawasaki T, Tokunaga F.
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 直鎖状ユビキチン修飾を介した炎症・免疫応答制御機構の研究2021
- Author(s)
  及川大輔
- Organizer
  第67回日本生化学会近畿支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] A novel LUBAC-associated protein plays important roles in inflammatory response through regulation of programmed cell death.2021
- Author(s)
  Tran Thi Thuy Linh、清水康平、及川大輔、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] LUBACユビキチンリガーゼと直鎖状ユビキチン鎖が筋萎縮性側索硬化症関連タンパク質TDP-43の細胞質内凝集形成を促進する2021
- Author(s)
  寺脇正剛、張強、及川大輔、林邦忠、布村一人、駒川晋輔、臼杵克之助、徳永文稔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 直鎖状ポリユビキチン鎖デコーダーZnUBPのNF-kBシグナル制御機構の解明2021
- Author(s)
  岩崎誠、長尾和哉、及川大輔、小迫英尊、徳永文稔、高橋宏隆、澤崎達也
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] Cellular functions regulated by complex-type ubiquitination including linear polyubiquitin chain2021
- Author(s)
  Tokunaga F, Terawaki S, Oikawa D, Shimizu K.
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] Cellular functions regulated by complex-type ubiquitination including linear polyubiquitin chain2021
- Author(s)
  Tokunaga F, Terawaki S, Oikawa D, Shimizu K.
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] LUBACユビキチンリガーゼと直鎖状ユビキチン鎖が筋萎縮性側索硬化症関連タンパク質TDP-43の細胞質内凝集形成を促進する2021
- Author(s)
  寺脇正剛、張強、及川大輔、林邦忠、布村一人、駒川晋輔、臼杵克之助、徳永文稔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] Identification of OTUD1 deubiquitinase as a regulator for innate immune responses, cell death, and inflammatory bowel disease2021
- Author(s)
  Oikawa D, Gi M, Kosako H, Shimizu K, Shiota M, Takahashi H, Sawasaki T, Tokunaga F.
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] A novel LUBAC-associated protein regulates NF-kB activation, apoptosis and necroptosis pathway.2021
- Author(s)
  清水康平、Tran Thi Thuy Linh、及川大輔、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] 直鎖状ユビキチン修飾を介した炎症・免疫応答制御機構の研究2021
- Author(s)
  及川大輔
- Organizer
  第67回日本生化学会近畿支部例会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] A novel LUBAC-associated protein regulates NF-kB activation, apoptosis and necroptosis pathway.2021
- Author(s)
  清水康平、Tran Thi Thuy Linh、及川大輔、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] A novel LUBAC-associated protein plays important roles in inflammatory response through regulation of programmed cell death.2021
- Author(s)
  Tran Thi Thuy Linh、清水康平、及川大輔、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] Cellular functions regulated by complex-type ubiquitination including linear polyubiquitin chain2021
- Author(s)
  Tokunaga F, Terawaki S, Oikawa D, Shimizu K.
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] A novel LUBAC-associated protein regulates NF-kB activation, apoptosis and necroptosis pathway.2021
- Author(s)
  清水康平、Tran Thi Thuy Linh、及川大輔、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] LUBACユビキチンリガーゼと直鎖状ユビキチン鎖が筋萎縮性側索硬化症関連タンパク質TDP-43の細胞質内凝集形成を促進する2021
- Author(s)
  寺脇正剛、張強、及川大輔、林邦忠、布村一人、駒川晋輔、臼杵克之助、徳永文稔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] 全身性エリテマトーデス、皮膚筋炎、自己免疫水泡症における協調したレトロトランスポゾンとI型IFN経路の特徴2021
- Author(s)
  栗山裕子、清水晶、金井早紀、及川大輔、徳永文稔、石川治、茂木精一郎
- Organizer
  第68回北関東医学会総会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 全身性エリテマトーデス、皮膚筋炎、自己免疫水泡症における協調したレトロトランスポゾンとⅠ型IFN経路の特徴2021
- Author(s)
  栗山裕子、清水晶、金井早紀、及川大輔、徳永文稔、石川治、茂木精一郎
- Organizer
  第68回北関東医学会総会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] A novel LUBAC-associated protein plays important roles in inflammatory response through regulation of programmed cell death.2021
- Author(s)
  Tran Thi Thuy Linh、清水康平、及川大輔、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] A novel LUBAC-associated protein regulates NF-kB activation, apoptosis and necroptosis pathway.2021
- Author(s)
  清水康平、Tran Thi Thuy Linh、及川大輔、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] Cellular functions regulated by complex-type ubiquitination including linear polyubiquitin chain2021
- Author(s)
  Tokunaga F, Terawaki S, Oikawa D, Shimizu K.
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 直鎖状ポリユビキチン鎖デコーダーZnUBPのNF-kBシグナル制御機構の解明2021
- Author(s)
  岩崎誠、長尾和哉、及川大輔、小迫英尊、徳永文稔、高橋宏隆、澤崎達也
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] UBACユビキチンリガーゼと直鎖状ユビキチン鎖が筋萎縮性側索硬化症関連タンパク質TDP-43の細胞質内凝集形成を促進する2021
- Author(s)
  寺脇正剛、張強、及川大輔、林邦忠、布村一人、駒川晋輔、臼杵克之助、徳永文稔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 全身性エリテマトーデス、皮膚筋炎、自己免疫水泡症における協調したレトロトランスポゾンとⅠ型IFN経路の特徴2021
- Author(s)
  栗山裕子、清水晶、金井早紀、及川大輔、徳永文稔、石川治、茂木精一郎
- Organizer
  第68回北関東医学会総会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] 直鎖状ユビキチン修飾を介した炎症・免疫応答制御機構の研究2021
- Author(s)
  及川大輔
- Organizer
  第67回日本生化学会近畿支部例会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 直鎖状ユビキチン修飾を介した炎症・免疫応答制御機構の研究2021
- Author(s)
  及川大輔
- Organizer
  第67回日本生化学会近畿支部例会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] 直鎖状ポリユビキチン鎖デコーダーZnUBPのNF-kBシグナル制御機構の解明2021
- Author(s)
  岩崎誠、長尾和哉、及川大輔、小迫英尊、徳永文稔、高橋宏隆、澤崎達也
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] 直鎖状ポリユビキチン鎖デコーダーZnUBPのNF-kBシグナル制御機構の解明2021
- Author(s)
  岩崎誠、長尾和哉、及川大輔、小迫英尊、徳永文稔、高橋宏隆、澤崎達也
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06873
[Presentation] A novel LUBAC-associated protein plays important roles in inflammatory response through regulation of programmed cell death.2021
- Author(s)
  Tran Thi Thuy Linh、清水康平、及川大輔、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-21H00291
[Presentation] 全身性エリテマトーデス、皮膚筋炎、自己免疫水泡症における協調したレトロトランスポゾンとⅠ型IFN経路の特徴2021
- Author(s)
  栗山裕子、清水晶、金井早紀、及川大輔、徳永文稔、石川治、茂木精一郎
- Organizer
  第68回北関東医学会総会
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] Comprehensive identification and functional analysis of novel decoder molecules for linear polyubiquitin chain using a wheat cell-free system.2020
- Author(s)
  Takahashi H, Nagao K, Iwasaki M, Sato Y, Oikawa D, Tokunaga F, Sawasaki T.
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] Comprehensive identification and functional analysis of novel decoder molecules for linear polyubiquitin chain using a wheat cell-free system.2020
- Author(s)
  Takahashi H, Nagao K, Iwasaki M, Sato Y, Oikawa D, Tokunaga F, Sawasaki T.
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] Comprehensive identification and functional analysis of novel decoder molecules for linear polyubiquitin chain using a wheat cell-free system.2020
- Author(s)
  Takahashi H, Nagao K, Iwasaki M, Sato Y, Oikawa D, Tokunaga F, Sawasaki T.
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] NDP52のユビキチン結合性を介した炎症応答・細胞死制御とLUBAC阻害剤の影響2020
- Author(s)
  宮下裕久、及川大輔、寺脇正剛、徳永文稔
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] Involvement of atypical linear ubiquitin as a scaffold for inflammatory signaling and proteinopathy2020
- Author(s)
  徳永文稔、伊東秀文、及川大輔
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] Mathematical Model of Linear Ubiquitination-mediated NF-κB Activation Pathway2020
- Author(s)
  Tokunaga F, Oikawa D, Hatanaka N, Suzuki T.
- Organizer
  JSPS Core-to-Core Program “Establishing International Research Network of Mathematical Oncology"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] Mathematical Model of Linear Ubiquitination-mediated NF-κB Activation Pathway2020
- Author(s)
  Tokunaga F, Oikawa D, Hatanaka N, Suzuki T.
- Organizer
  JSPS Core-to-Core Program “Establishing International Research Network of Mathematical Oncology"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] Involvement of atypical linear ubiquitin as a scaffold for inflammatory signaling and proteinopathy2020
- Author(s)
  徳永文稔、伊東秀文、及川大輔
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] NDP52のユビキチン結合性を介した炎症応答・細胞死制御とLUBAC阻害剤の影響2020
- Author(s)
  宮下裕久、及川大輔、寺脇正剛、徳永文稔
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] NDP52のユビキチン結合性を介した炎症応答・細胞死制御とLUBAC阻害剤の影響2020
- Author(s)
  宮下裕久、及川大輔、寺脇正剛、徳永文稔
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.2020
- Author(s)
  Oikawa D, Tokunaga F.
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 非定型型直鎖状ユビキチン鎖を足場とするNF-κB活性化の細胞機能と数理モデル2020
- Author(s)
  徳永文稔、及川大輔、畑中尚也、鈴木貴
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] 非定型型直鎖状ユビキチン鎖を足場とするNF-κB活性化の細胞機能と数理モデル2020
- Author(s)
  徳永文稔、及川大輔、畑中尚也、鈴木貴
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.2020
- Author(s)
  Oikawa D, Tokunaga F.
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.2020
- Author(s)
  Oikawa D, Tokunaga F.
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05337
[Presentation] Involvement of atypical linear ubiquitin as a scaffold for inflammatory signaling and proteinopathy2020
- Author(s)
  徳永文稔、伊東秀文、及川大輔
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] Mathematical Model of Linear Ubiquitination-mediated NF-κB Activation Pathway2020
- Author(s)
  Tokunaga F, Oikawa D, Hatanaka N, Suzuki T.
- Organizer
  JSPS Core-to-Core Program “Establishing International Research Network of Mathematical Oncology"
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] 非定型型直鎖状ユビキチン鎖を足場とするNF-κB活性化の細胞機能と数理モデル2020
- Author(s)
  徳永文稔、及川大輔、畑中尚也、鈴木貴
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] LUBACによるT細胞受容体シグナル制御に関する細胞・生化学及び数理モデル解析2019
- Author(s)
  及川大輔、畑中尚也、鈴木貴、徳永文稔
- Organizer
  第14日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] LUBACによるT細胞受容体シグナル制御に関する細胞・生化学及び数理モデル解析2019
- Author(s)
  及川大輔、畑中尚也、鈴木貴、徳永文稔
- Organizer
  第14日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] "まっすぐ”なユビキチン鎖を狙った創薬アプローチ2019
- Author(s)
  及川大輔
- Organizer
  第9回CSJ化学フェスタ2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] LRBA DUF1088ドメインの自然免疫制御における重要性2019
- Author(s)
  及川大輔、駒倉啓大、福士雅也、入江崇、堀居拓郎、畑田出穂、坂口剛正、徳永文稔
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] LUBACシグナルソームによる自然免疫応答の選択的制御2019
- Author(s)
  及川大輔、駒倉啓大、阿部貴則、飯尾清誠、小比賀真吾、勝矢健、花田和希、坂本信二、徳永文稔
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] OTUD1, an OUT family deubiquitinase, involved in innate immune response2019
- Author(s)
  Komakura K, Goto E, Oikawa D, Abe T, Tokunaga F.
- Organizer
  1st International symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 直鎖状ユビキチン鎖を足場とした免疫シグナル制御に関する数理モデル解析2019
- Author(s)
  及川大輔
- Organizer
  日本応用数理学会2019年度年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] 自然免疫制御に関わる新規脱ユビキチン化酵素OTUD1の同定と生理機能解析2019
- Author(s)
  駒倉啓大、及川大輔、徳永文稔
- Organizer
  第24回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] 自然免疫制御に関わる新規脱ユビキチン化酵素OTUD1の同定と生理機能解析2019
- Author(s)
  駒倉啓大、及川大輔、徳永文稔
- Organizer
  第24回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 直鎖状ユビキチン鎖を足場とした免疫シグナル制御に関する数理モデル解析2019
- Author(s)
  及川大輔
- Organizer
  日本応用数理学会2019年度年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 脱ユビキチン化酵素OTUD1によるNF-κB経路とインターフェロン産生経路の相反的制御2019
- Author(s)
  駒倉啓大、及川大輔、徳永文稔
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] Screening and characterization of novel LUBAC inhibitors, HOIPINs.2019
- Author(s)
  Oikawa D, Katsuya K, Hanada K, Sugawara K, Tsuruta D, Sakamoto S, Tokuanga F.
- Organizer
  Cold Spring Harbor Laboratory meeting: Ubiquitins, Autophagy & Disease.
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] 直鎖状ポリユビキチン鎖結合タンパク質ZnUBPファミリーのNF-κB抑制機構の解明2019
- Author(s)
  高橋宏隆、及川大輔、長尾和哉、岩崎誠、今井祐記、徳永文稔、澤崎達也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] Subquinocin, a small molecule inhibitor for USPs, promotes NF-kB signal by stabilization of M1-linked polyubiquitin2019
- Author(s)
  Takahashi H, Yamanaka S, Sato Y, Oikawa D, Fukai S, Tokunaga F, Sawasaki T.
- Organizer
  1st International symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] "まっすぐ”なユビキチン鎖を狙った創薬アプローチ2019
- Author(s)
  及川大輔
- Organizer
  第9回CSJ化学フェスタ2019
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] Screening and characterization of novel LUBAC inhibitors, HOIPINs.2019
- Author(s)
  Oikawa D, Katsuya K, Hanada K, Sugawara K, Tsuruta D, Sakamoto S, Tokuanga F.
- Organizer
  Cold Spring Harbor Laboratory meeting: Ubiquitins, Autophagy & Disease.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 脱ユビキチン化酵素OTUD1によるNF-κB経路とインターフェロン産生経路の相反的制御2019
- Author(s)
  駒倉啓大、及川大輔、徳永文稔
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 新規LUBAC阻害剤の同定と合成展開による阻害能亢進2019
- Author(s)
  及川大輔
- Organizer
  第2回ユビキチン研究会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] Identification and characterization of small-molecule LUBAC inhibitors, HOIPINs2019
- Author(s)
  Oikawa D, Katsuya K, Hanada K, Sakamoto S, Tokunaga F.
- Organizer
  1st International symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] LRBA DUF1088ドメインの自然免疫制御における重要性2019
- Author(s)
  及川大輔、駒倉啓大、福士雅也、入江崇、堀居拓郎、畑田出穂、坂口剛正、徳永文稔
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 直鎖状ポリユビキチン鎖結合タンパク質ZnUBPファミリーのNF-κB抑制機構の解明2019
- Author(s)
  高橋宏隆、及川大輔、長尾和哉、岩崎誠、今井祐記、徳永文稔、澤崎達也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-19H05296
[Presentation] LUBACシグナルソームによる自然免疫応答の選択的制御2019
- Author(s)
  及川大輔、駒倉啓大、阿部貴則、飯尾清誠、小比賀真吾、勝矢健、花田和希、坂本信二、徳永文稔
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 新規LUBAC阻害剤の探索と機能評価2018
- Author(s)
  及川大輔、花田和希、勝矢健、菅原弘二、水上裕加里、鶴田大輔、坂本信二、徳永文稔
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 自然免疫制御に関わる新規RING型E3（RNF126）の同定と機能解析2018
- Author(s)
  阿部貴則、及川大輔、寺脇正剛、後藤栄治、高橋宏隆、大竹史明、川原裕之、堀居拓郎、畑田出穂、佐伯泰、田中啓二、澤崎達也、徳永文稔
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] OTUD1は自然免疫制御に関わる脱ユビキチン化酵素である2018
- Author(s)
  駒倉啓大、後藤栄治、及川大輔、阿部貴則、徳永文稔
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] TCRシグナルにおける直鎖状ユビキチン化シグナルの数理モデル解析2018
- Author(s)
  後藤栄治、浜田大輔、及川大輔、徳永文稔
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 新規LUBAC阻害剤、HOIPIN-1の機能評価と病態抑制効果2018
- Author(s)
  及川大輔
- Organizer
  第1回ユビキチン研究会
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] 自然免疫制御に関わる新規脱ユビキチン化酵素（OTUD1）の同定と生理機能解析2018
- Author(s)
  駒倉啓大、後藤栄治、及川大輔、阿部貴則、徳永文稔
- Organizer
  第13回臨床ストレス応答学会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 直鎖状ユビキチン鎖生成酵素(LUBAC)に対する新規阻害剤の開発と炎症病態抑制2018
- Author(s)
  及川大輔、花田和希、勝矢健、菅原弘二、水上裕加里、鶴田大輔、坂本信二、徳永文稔
- Organizer
  第13回臨床ストレス応答学会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] 新規LUBAC阻害剤、HOIPIN-1の作用機序と病態抑制効果2018
- Author(s)
  及川大輔、花田和希、菅原弘二、寺脇正剛、水上裕加里、鶴田大輔、坂本信二、徳永文稔
- Organizer
  第65回日本生化学会近畿支部会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] Characterization of a novel LUBAC inhibitor, HOIPIN-12018
- Author(s)
  Oikawa D, Hanada K, Terawaki S, Sakamoto S, Tokunaga F.
- Organizer
  Keystone Symposium; Ubiquitin Signaling.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] T細胞受容体を介したNF-κBシグナル制御の数理シミュレーション2018
- Author(s)
  後藤栄治、濱田大輔、及川大輔、鈴木貴、徳永文稔
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] オートファジーアダプターNDP52による新規NF-κB・細胞死制御機構2018
- Author(s)
  及川大輔、駒倉啓大、徳永文稔
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06967
[Presentation] マイトファジー受容体のユビキチン結合性はNF-κBと細胞死制御に関与する2017
- Author(s)
  葛谷早喜子、及川大輔、徳永文稔
- Organizer
  バイオインターフェース先端マテリアルの創生第7回シンポジウム
- Place of Presentation
  大阪市立大学（大阪府大阪市）
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] マイトファジーアダプター(NDP52)のユビキチン結合性はNF-kBと細胞死制御に関与する2017
- Author(s)
  及川大輔、徳永文稔
- Organizer
  第64回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] 直鎖状ユビキチン鎖生成酵素(LUBAC)に対する新規阻害剤の細胞・生化学機構と疾患治療への応用2017
- Author(s)
  及川大輔、葛谷早喜子、花田和希、寺脇正剛、鶴田大輔、坂本信二、徳永文稔
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] NDP52のユビキチン結合性はNF-kBと細胞死制御に関与する2017
- Author(s)
  葛谷早喜子、及川大輔、徳永文稔
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] 直鎖状ユビキチン鎖生成酵素(LUBAC)に対する新規阻害剤によるNF-kB制御と疾患応用を目指した基礎解析2017
- Author(s)
  及川大輔、花田和希、寺脇正剛、葛谷早喜子、菅原弘二、鶴田大輔、坂本信二、徳永文稔
- Organizer
  第12回臨床ストレス応答学会
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] Optineurin遺伝子変異に伴うALS発症における直鎖状ポリユビキチン鎖の寄与2016
- Author(s)
  及川大輔、中澤世識、石井亮平、綾木孝、石谷隆一郎、伊東秀文、濡木理、徳永文稔
- Organizer
  第494回大阪市医学会
- Place of Presentation
  大阪市立大学（大阪府大阪市）
- Year and Date
  2016-10-20
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] Linear Ubiquitin binding of optineurin regulates NF-κB signaling.2015
- Author(s)
  Nakazawa S, Ishii R, Oikawa D, Ishitani R, Nureki O, Tokunaga F.
- Organizer
  2nd International symposium on "Protein modifications in Pathogenic Dysregulation of Signaling"
- Place of Presentation
  The University of Tokyo
- Year and Date
  2015-01-23
- Data Source
  KAKENHI-PROJECT-25870118
[Presentation] 表皮基底層にⅦ型コラーゲン沈着が見られた優性栄養障害型表皮水泡症（前脛骨型）の1例2015
- Author(s)
  服部麻衣、清水晶、加藤円香、天野博雄、山本明美、中野創、澤村大輔、及川大輔、亀井希代子、徳永文、石川治
- Organizer
  第62回北関東医学会総会
- Place of Presentation
  群馬大学
- Year and Date
  2015-10-01
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] Generalized verrucosis caused by a GATA2 deficiency2015
- Author(s)
  Mai Hattori, Akira Shimizu, Hiroo Amano, Osamu Ishikawa, Takeki Mitsui, Kyoichi Kaira, Daisuke Oikawa, Fuminori Tokunaga, Hajime Nakano, Daisuke Sawamura
- Organizer
  日本研究皮膚科学会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] GATA2遺伝子変異によるgeneralized verrucosis発症メカニズムの検討2015
- Author(s)
  服部麻衣、清水晶、石川治、及川大輔、徳永文稔、解良恭一、三井健揮、中野創、澤村大輔
- Organizer
  第66回日本皮膚科学会中部支部学術大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] Optineurinによる直鎖状ポリユビキチン鎖結合を介したNF-κBとアポトーシス制御2015
- Author(s)
  及川大輔、石井亮平、中澤世識、石谷隆一郎、濡木理、徳永文稔
- Organizer
  第67回日本細胞生物学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] 直鎖状ユビキチン鎖産生酵素(LUBAC)の新規調節因子の同定と免疫・炎症制御2015
- Author(s)
  阿部貴則、及川大輔、高橋宏隆、澤崎達也、徳永文稔
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] IL-1βの分子制御を利用した炎症可視化モデルマウスの開発2015
- Author(s)
  赤井良子、及川大輔、豊嶋孝恵、吉野麻由子、岩脇隆夫
- Organizer
  第11回日本疲労学会
- Place of Presentation
  山口県総合保健会館
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] Optineurin遺伝子変異に伴うALS発症における直鎖状ポリユビキチン鎖の寄与2015
- Author(s)
  及川大輔、中澤世識、石井亮平、綾木孝、石谷隆一郎、伊東秀文、濡木理、徳永文稔
- Organizer
  第10回臨床ストレス応答学会
- Place of Presentation
  東京農工大学
- Year and Date
  2015-11-06
- Data Source
  KAKENHI-PROJECT-15K08259
[Presentation] Optineurin regulates NF-κB via linear ubiquitin binding.2014
- Author(s)
  Nakazawa S, Oikawa D, Ishii R, Hatada I, Nureki O, Tokunaga F.
- Organizer
  International symposium on "Homeostasis through development, life, and diseases"
- Place of Presentation
  Gunma University
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-25870118
[Presentation] 胎盤での Cathepsin 遺伝子発現制御における IRE1alpha および XBP1 の役割2013
- Author(s)
  岩脇隆夫、及川大輔
- Organizer
  第60回北関東医学会総会
- Place of Presentation
  群馬大学医学部刀城会館
- Data Source
  KAKENHI-PROJECT-25870118
[Presentation] High-sensitive in vivo Imaging of Oxidative Stress with OKD48 mice.2013
- Author(s)
  Daisuke Oikawa, Ryoko Akai, Mio Tokuda, Takao Iwawaki.
- Organizer
  日本組織培養学会第86回大会
- Place of Presentation
  独立行政法人産業技術総合研究所
- Invited
- Data Source
  KAKENHI-PROJECT-25870118
[Presentation] 哺乳動物IRE1αによる小胞体ストレス感知は、異常タンパク質との直接結合ではなく、BiPの解離に強く依存する。2008
- Author(s)
  及川大輔, 木俣行雄, 河野憲二, 岩脇隆夫
- Organizer
  BMB2008(一般口頭発表)
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20770113
[Presentation] 哺乳動物IRE1αによる小胞体ストレス感知は、異常タンパク質との直接結合ではなく、BiPの解離に強く依存する。2008
- Author(s)
  及川大輔, 木俣行雄, 河野憲二, 岩脇隆夫
- Organizer
  BMB2008(ポスター発表)
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20770113
[Presentation] 哺乳動物IRE1αによる異常タンパク質感知機構の解析2008
- Author(s)
  及川大輔
- Organizer
  「タンパク質の社会」若手ワークショップ(口頭発表)
- Place of Presentation
  東京大学検見川セミナーハウス(千葉)
- Year and Date
  2008-09-26
- Data Source
  KAKENHI-PROJECT-20770113
[Presentation] 新規LUBACシグナル複合体構成因子の探索と細胞機能解析
- Author(s)
  及川大輔、中澤世識、徳永文稔
- Organizer
  第66回日本細胞生物学会
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-25870118
[Presentation] Optineurinの直鎖状ユビキチン結合を介したNF-κB 抑制と疾患との関連
- Author(s)
  及川大輔、石井亮平、中澤世識、石谷隆一郎、濡木理、徳永文稔
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25870118
[Presentation] OptineurinによるNF-κBシグナル制御の細胞機構と疾患
- Author(s)
  及川大輔、石井亮平、中澤世識、石谷隆一郎、濡木理、徳永文稔
- Organizer
  第9回臨床ストレス応答学会
- Place of Presentation
  岡山大学
- Year and Date
  2014-11-01 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25870118

1. 徳永文稔 (00212069)

# of Collaborated Projects: 4 results

# of Collaborated Products: 78 results
2. SAWASAKI Tatsuya (50314969)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. 清水康平 (70727073)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 中嶋秀満 (30405360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 疋田貴俊 (70421378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. チェンバーズジェームズ (00621682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 永井義隆 (60335354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中山淳 (60743408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISHITANI Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 山本瑞生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 鰐渕英機

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 本田茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 寺脇正剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 清水晶

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 鈴木貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. LE Thuy

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 若松馨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 岩崎成仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oikawa Daisuke 及川 大輔

OIKAWA Daisuke 及川 大輔

及川 大輔 オイカワ ダイスケ

Research Projects

Research Products

Co-Researchers

複雑化ユビキチン修飾による細胞生死制御の細胞・個体レベルでの解析と病態との関連

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

直鎖状ユビキチン鎖によるタンパク質寿命制御機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Therapeutic strategy in brain amyloidosis based on the GAPDH aggregate common cross-seed hypothesis

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

複合型ユビキチン鎖を標的とした筋萎縮性側索硬化症の病態解明と創薬シーズの開拓

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

直鎖状ユビキチン代謝を制御する新規ケモテクノロジーによる疾患病態の抑制Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Study on the Novel Cellular Regulatory Mechanism with LUBAC as a Scaffold and Its Application to Disease TherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

直鎖状ユビキチン鎖が制御する新規オートファジー機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

直鎖状ユビキチン鎖を標的としたケモテクノロジーによる病態解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of biological defense responses via linear ubiquitin chains and its contribution to disease onsetPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Regulation of cellular signal transduction by novel immunological factorPrincipal Investigator

Principal Investigator

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Research Institution

Development of high-sensitive mitochondrial stress reporter for in vivo ROS-damage imagingPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

試験管内再構築系による異常タンパク質感知機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] The hypothetical molecular mechanism of the ethnic variations in the manifestation of age-related macular degeneration; focuses on the functions of the most significant susceptibility genes2024

Author(s)

Oikawa Daisuke 及川大輔

OIKAWA Daisuke 及川大輔

及川大輔オイカワダイスケ