Matsumoto Shinji 松本真司

… Alternative Names

MATSUMOTO Shinji 松本真司

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Researcher Number	20572324
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(歯学域), 教授
Affiliation (based on the past Project Information) *help	2025: 徳島大学, 大学院医歯薬学研究部(歯学域), 教授 2021 – 2023: 大阪大学, 大学院医学系研究科, 准教授 2021: 大阪大学, 医学系研究科, 准教授 2018 – 2020: 大阪大学, 医学系研究科, 助教 2017: 大阪大学, 医学(系)研究科(研究院), 助教 … More 2016: 大阪大学, 医学系研究科, 助教 2015: 大阪大学, 医学(系)研究科(研究院), 特任助教 (常勤) 2015: 大阪大学, 大学院医学系研究科, 特任助教 2013 – 2015: 大阪大学, 医学(系)研究科(研究院), 特任助教(常勤) 2012 – 2014: 大阪大学, 医学(系)研究科(研究院), 助教 2012: 大阪大学, 医学系研究科, 助教 2011: 大阪大学, 医学(系)研究科(研究院), 招へい研究員 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 50010:Tumor biology-related / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Medium-sized Section 48:Biomedical structure and function and related fields / Medium-sized Section 50:Oncology and related fields / Basic Section 50010:Tumor biology-related / Biological Sciences / Tumor biology
Keywords	Principal Investigator Wnt / GREB1 / アンチセンス核酸 / Arl4c / Wntシグナル / 小児固形がん / 神経芽腫 / Ras / 細胞浸潤 / MT1-MMP … More / MMP14 / KRas / 転移 / 膵がん / IQGAP1 / 導管形成 / 腺房分化 / KIT / 分化 / 導管 / 腺房 / 唾液腺 / 外分泌腺 / 上皮分岐管腔形成 / 上皮管腔形成 / YAP/TAZ / Arｌ４ｃ / EGF / 極性 / 上皮 / Wnt シグナル / 分枝管腔形成 … More Except Principal Investigator CKAP4 / Wntシグナル / Wnt / Arl4c / シグナル伝達 / 炎症 / Wnt5a / 細胞生物学 / CXCR2 / ジフテリア毒素 / 食道 / 扁平上皮 / 腺細胞 / 唾液腺 / AQP3 / 扁平上皮組織 / 腺組織 / 組織幹細胞 / 腸管炎症 / TGFβ / 大腸炎 / 1細胞シーケンス / 大腸がん / 線維芽細胞 / 肝細胞癌サブタイプ / オルガノイド / DKK1 / 肝細胞癌 / 上皮管腔形成 / FGF / HGF / 増殖因子 / 細胞外基質 / 上皮管腔組織形成 / EGF / Dkk1 / 極性 / 上皮菅腔組織形成 / ハイスループットスクリーニング / 転移 / 癌 / エンドサイト―シス / 炎症性腸疾患 / サイトカイン / エンドサイトーシス / がん Less

唾液腺修復における胎生期型先祖返り幹細胞の機能解明と再生医療基盤の構築Principal Investigator
- Principal Investigator
  
  松本真司
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  The University of Tokushima
DKK1/CKAP4シグナルを標的とした肝細胞癌に対する新規抗癌治療の開発
- Principal Investigator
  
  権英寿
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kobe University
Fibroblast remodeling in tumorigenesis based on inflammation
- Principal Investigator
  
  Akira Kikuchi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Osaka University
Identification of novel tissue-specific stem and progenitor cells responding to Wnt signaling
- Principal Investigator
  
  菊池章
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Osaka University
GREB1による小児固形がん発症機序の解明Principal Investigator
- Principal Investigator
  
  松本真司
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Osaka University
Regulation of cell proliferation through interaction between Arl4c and IQGAP1 in pancreatic cancer.Principal Investigator
- Principal Investigator
  
  Matsumoto Shinji
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Osaka University
Regulation of exocrine glands development by Wnt signalingPrincipal Investigator
- Principal Investigator
  
  Matsumoto Shinji
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Elucidation of the molecular mechanism of the malignant transformation of cancer with the Wnt5a signal and development of the molecular target medicine
- Principal Investigator
  
  Kikuchi Akira
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Tumor biology
- Research Institution
  Osaka University
Wnt signaling promotes epithelial tubulogenesis through the regulation of cell morphology and proliferationPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Shinji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Spatial regulation of branching tubulogenesis by Wnt signalingPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Shinji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Moleuclar mechanism for the formation and maintenance of epithelial tubulogenesis with branching
- Principal Investigator
  
  Kikuchi Akira
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Book Patent

[Book] G. I. Research「消化管の再生医療」 (In vitro実験系を用いた上皮管腔組織形成の分子基盤の確立)2014
- Author(s)
  松本真司、菊池　章
- Total Pages
  72
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-25860211
[Book] Wnt Signaling　(Chapter8, Wnt signaling in Development and Disease)2014
- Author(s)
  Akira Kikuchi, Shinji Matsumoto, Katsumi Fumoto, and Akira Sato.
- Total Pages
  472
- Publisher
  John Wiley and Sons, Inc
- Data Source
  KAKENHI-PLANNED-23112004
[Book] Wnt Signaling　(Chapter8, Wnt signaling in Development and Disease)2014
- Author(s)
  Akira Kikuchi, Shinji Matsumoto, Katsumi Fumoto, and Akira Sato.
- Total Pages
  472
- Publisher
  John Wiley and Sons, Inc
- Data Source
  KAKENHI-PROJECT-25250018
[Book] プログレッシブ生命科学 (細胞増殖・運動・死とがん)2014
- Author(s)
  菊池　章、松本真司
- Total Pages
  312
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-25860211
[Book] Wnt Signaling　(Chapter8, Wnt signaling in Development and Disease)2014
- Author(s)
  Kikuchi, A., Matsumoto, S., Fumoto, K., and Sato, A.
- Total Pages
  472
- Publisher
  John Wiley and Sons, Inc
- Data Source
  KAKENHI-PLANNED-23112004
[Book] Wnt Signaling in Development and Disease: Molecular Mechanisms and Biological Functions2014
- Author(s)
  Akira kikuchi, Shinji Matsumoto, Katsumi Fumoto, and Akira Sato
- Total Pages
  472
- Publisher
  Wiley-Blackwell
- Data Source
  KAKENHI-PROJECT-25860211
[Book] 生体の科学　特集　細胞接着の制御2013
- Author(s)
  松本　真司、菊池　章
- Total Pages
  292
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-25860211
[Book] 細胞工学 Vol.32 No.42013
- Author(s)
  松本　真司
- Total Pages
  496
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-23790333
[Book] 実験医学増刊　Vol.30 No.52012
- Author(s)
  菊池　章、松本真司
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23790333
[Book] がん生物学イラストレイテッド2011
- Author(s)
  菊池　章、松本真司
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23790333
[Book] 実験医学増刊　Vol.29 No.22011
- Author(s)
  菊池　章、佐藤　朗、松本　真司
- Total Pages
  10
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23790333
[Journal Article] DKK1‐CKAP4 signal axis promotes hepatocellular carcinoma aggressiveness2023
- Author(s)
  Sada Ryota、Iguchi Kosuke、Matsumoto Shinji、Kimura Hirokazu、Zen Yoh、Akita Masayuki、Gon Hidetoshi、Fukumoto Takumi、Kikuchi Akira
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 5 Pages: 2063-2077
- DOI
  10.1111/cas.15743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15511, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-20K16330
[Journal Article] Dickkopf signaling, beyond Wnt-mediated biology2022
- Author(s)
  Kikuchi Akira、Matsumoto Shinji、Sada Ryota
- Journal Title
  
  Seminars in Cell & Developmental Biology
  
  Volume: 125 Pages: 55-65
- DOI
  10.1016/j.semcdb.2021.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15511, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-20K16330
[Journal Article] Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion.2021
- Author(s)
  Harada A, Matsumoto S, Yasumizu Y, Shojima K, Akama T, Eguchi H, Kikuchi A.
- Journal Title
  
  Elife.
  
  Volume: 10
- DOI
  10.7554/elife.66721
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06956, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K07121
[Journal Article] TAZ inhibits acinar cell differentiation but promotes immature ductal cell proliferation in adult mouse salivary glands.2021
- Author(s)
  Miyachi Y, Nishio M, Otani J, Matsumoto S, Kikuchi A, Mak TW, Maehama T, Suzuki A.
- Journal Title
  
  Genes Cells.
  
  Volume: 26(9) Issue: 9 Pages: 714-726
- DOI
  10.1111/gtc.12879
- NAID
  120007148944
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06956, KAKENHI-PUBLICLY-20H04905, KAKENHI-PROJECT-21H04806, KAKENHI-PROJECT-20K07572, KAKENHI-PROJECT-20K07590, KAKENHI-PROJECT-20K20661, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K07121
[Journal Article] RAF1-MEK/ERK pathway-dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation.2021
- Author(s)
  Fujii S, Ishibashi T, Kokura M, Fujimoto T, Matsumoto S, Shidara S, Kurppa KJ, Pape J, Caton J, Morgan PR, Heikinheimo K, Kikuchi A, Jimi E, Kiyoshima T.
- Journal Title
  
  J Pathol.
  
  Volume: 256(1) Issue: 1 Pages: 119-133
- DOI
  10.1002/path.5814
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06956, KAKENHI-PROJECT-20K09906, KAKENHI-PROJECT-20K10096, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K07121
[Journal Article] YAP signaling induces PIEZO1 to promote oral squamous cell carcinoma cell proliferation2020
- Author(s)
  Hasegawa Kana、Fujii Shinsuke、Matsumoto Shinji、Tajiri Yudai、Kikuchi Akira、Kiyoshima Tamotsu
- Journal Title
  
  The Journal of Pathology
  
  Volume: 253 Issue: 1 Pages: 80-93
- DOI
  10.1002/path.5553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09906, KAKENHI-PROJECT-20K10096, KAKENHI-PROJECT-19K18966, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K07121
[Journal Article] ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target2020
- Author(s)
  Kimura Kenji、Matsumoto Shinji、Harada Takeshi、Morii Eiichi、Nagatomo Izumi、Shintani Yasushi、Kikuchi Akira
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 3 Pages: 951-961
- DOI
  10.1111/cas.14303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08633, KAKENHI-PROJECT-18K06956, KAKENHI-PROJECT-19K22563, KAKENHI-PUBLICLY-18H04861, KAKENHI-PUBLICLY-18H05101, KAKENHI-PROJECT-19H03452, KAKENHI-PROJECT-16H06374
[Journal Article] Palmitoylated CKAP4 regulates mitochondrial functions through an interaction with VDAC2 at ER?mitochondria contact sites2020
- Author(s)
  Harada Takeshi、Sada Ryota、Osugi Yoshito、Matsumoto Shinji、Matsuda Tomoki、Hayashi-Nishino Mitsuko、Nagai Takeharu、Harada Akihiro、Kikuchi Akira
- Journal Title
  
  Journal of Cell Science
  
  Volume: 133 Issue: 21
- DOI
  10.1242/jcs.249045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06956, KAKENHI-PROJECT-20K07357, KAKENHI-PROJECT-16H06374, KAKENHI-PROJECT-18H02594, KAKENHI-PROJECT-17K08633, KAKENHI-PROJECT-19K22563, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06422
[Journal Article] Chemically Modified Antisense Oligonucleotide Against ARL4C Inhibits Primary and Metastatic Liver Tumor Growth2019
- Author(s)
  Harada Takeshi、Matsumoto Shinji、Hirota Suguru、Kimura Hirokazu、Fujii Shinsuke、Kasahara Yuuya、Gon Hidetoshi、Yoshida Toshihiko、Itoh Tomoo、Haraguchi Naotsugu、Mizushima Tsunekazu、Noda Takehiro、Eguchi Hidetoshi、Nojima Satoshi、Morii Eiichi、Fukumoto Takumi、Obika Satoshi、Kikuchi Akira
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 18 Issue: 3 Pages: 602-612
- DOI
  10.1158/1535-7163.mct-18-0824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08633, KAKENHI-PROJECT-18K06956, KAKENHI-PUBLICLY-18H05101, KAKENHI-PROJECT-15K08272, KAKENHI-PROJECT-16K11501, KAKENHI-PROJECT-18K15064, KAKENHI-PROJECT-16H06374
[Journal Article] GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFβ signaling.2019
- Author(s)
  Matsumoto S, Yamamichi T, Shinzawa K, Kasahara Y, Nojima S, Kodama T, Obika S, Takehara T, Morii E, Okuyama H, Kikuchi A.
- Journal Title
  
  Nature Communications
  
  Volume: 28 Issue: 1 Pages: 3882-3882
- DOI
  10.1038/s41467-019-11533-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06956, KAKENHI-PROJECT-19K22563, KAKENHI-PROJECT-19K16557, KAKENHI-PUBLICLY-18H04861, KAKENHI-PUBLICLY-18H05101, KAKENHI-PROJECT-16H06374
[Journal Article] Wnt/β-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development2019
- Author(s)
  Fujii Shinsuke、Nagata Kengo、Matsumoto Shinji、Kohashi Ken-ichi、Kikuchi Akira、Oda Yoshinao、Kiyoshima Tamotsu、Wada Naohisa
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 4257-4257
- DOI
  10.1038/s41598-019-39686-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06956, KAKENHI-PROJECT-15H05023, KAKENHI-PROJECT-15K08272, KAKENHI-PROJECT-16K11501, KAKENHI-PROJECT-16K11448, KAKENHI-PROJECT-17K08722, KAKENHI-PROJECT-16H06374
[Journal Article] LDL switches the LRP6 internalization route from flotillin dependent to clathrin dependent in hepatic cells2017
- Author(s)
  Yamamoto Hideki、Umeda Daisuke、Matsumoto Shinji、Kikuchi Akira
- Journal Title
  
  Journal of Cell Science
  
  Volume: 130 Issue: 20 Pages: 3542-3556
- DOI
  10.1242/jcs.202135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08272, KAKENHI-PROJECT-16H06374
[Journal Article] Arl4c is a key regulator of tubulogenesis and tumourigenesis as a target gene of Wnt-β-catenin and groth factor-Ras signaling2017
- Author(s)
  Matsumoto, S., Fujii, S., Kikuchi, A.
- Journal Title
  
  J Biochem.
  
  Volume: 161 Issue: 1 Pages: 27-35
- DOI
  10.1093/jb/mvw069
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K11501, KAKENHI-PROJECT-15K08272, KAKENHI-PROJECT-16H06374
[Journal Article] Wnt-Myb pathway suppresses KIT expression to control the timing of salivary proacinar differentiation and duct formation.2016
- Author(s)
  Matsumoto, S., Kurimoto, T., Taketo, M., Fujii, S., and Kikuchi, A.
- Journal Title
  
  Development
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112004
[Journal Article] Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells.2016
- Author(s)
  Lim, BC., Matsumoto, S., Yamamoto, H., Mizuno, H., Kikuta, J., Ishii, M., and Kikuchi, A.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 129 Pages: 3115-3129
- DOI
  10.1242/jcs.185439
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-WRAPUP-16H01696, KAKENHI-PROJECT-16H02469, KAKENHI-PROJECT-15K08272, KAKENHI-PROJECT-16H06374
[Journal Article] Wnt-Myb pathway suppresses KIT expression to control the timing of salivary proacinar differentiation and duct formation.2016
- Author(s)
  Matsumoto, S., Kurimoto, T., Taketo, M., Fujii, S., and Kikuchi, A.
- Journal Title
  
  Development
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25250018
[Journal Article] Wnt-Myb pathway suppresses KIT expression to control the timing of salivary proacinar differentiation and duct formation.2016
- Author(s)
  Matsumoto, S., Kurimoto, T., Taketo, M., Fujii, S., and Kikuchi, A.
- Journal Title
  
  Development
  
  Volume: 143 Pages: 2311-2324
- DOI
  10.1242/dev.134486
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-WRAPUP-16H01696, KAKENHI-PROJECT-15K08272, KAKENHI-PROJECT-16K11501, KAKENHI-PROJECT-16H06374
[Journal Article] The P2Y2 receptor promotes Wnt3a and EGF-induced epithelial tubular formation of IEC6 cells by binding to integrins.2015
- Author(s)
  Ibuka, S., Matsumoto, S., Fujii, S., Kikuchi, A.
- Journal Title
  
  J Cell Sci.
  
  Volume: 128(11) Issue: 11 Pages: 2156-2168
- DOI
  10.1242/jcs.169060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08272, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-25861669, KAKENHI-PROJECT-26861547
[Journal Article] The Wnt5a-Ror2 axis promotes the signaling circuit between interleukin-12 and interferon-γ in colitis.2015
- Author(s)
  Sato, A., Kayama, H., Shojima, K., Matsumoto, S., Koyama, H., Minami, Y., Nojima, S., Morii, E., Honda, H., Takeda, K., Kikuchi, A.
- Journal Title
  
  Sci. Rep.
  
  Volume: 5 Issue: 1 Pages: 10536-10536
- DOI
  10.1038/srep10536
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08272, KAKENHI-PROJECT-15K08423, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PLANNED-23112007, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-26670157
[Journal Article] The P2Y2 receptor promotes Wnt3a and EGF-induced epithelial tubular formation of IEC6 cells by binding to integrins2015
- Author(s)
  Ibuka, S., Matsumoto, S., Fujii, S., and Kikuchi, A.
- Journal Title
  
  J. Cell Sci.
  
  Volume: In press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25250018
[Journal Article] Arl4c expression in colorectal and lung cancers promotes tumorigenesis and may represent a novel therapeutic target2015
- Author(s)
  Fujii, S., Matsumoto, S., Nojima, S. Morii, E., and Kikuchi, A.
- Journal Title
  
  Oncogene
  
  Volume: In press Issue: 37 Pages: 4834-4844
- DOI
  10.1038/onc.2014.402
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-25860211, KAKENHI-PROJECT-26861547
[Journal Article] A. Basolateral secretion of Wnt5a in polarized epithelial cells is required for apical lumen formation2015
- Author(s)
  Yamamoto, H., Awada, C., Matsumoto, S., Kaneiwa, T., Sugimoto, T., Takao, T., and Kikuchi
- Journal Title
  
  J. Cell Sci.
  
  Volume: 128 Pages: 1051-1063
- DOI
  10.1242/jcs.163683
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860211, KAKENHI-PROJECT-15K08272, KAKENHI-PROJECT-26460365, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-25250018
[Journal Article] The P2Y2 receptor promotes Wnt3a and EGF-induced epithelial tubular formation of IEC6 cells by binding to integrins2015
- Author(s)
  Ibuka, S., Matsumoto, S., Fujii, S., and Kikuchi, A.
- Journal Title
  
  J. Cell Sci.
  
  Volume: In press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23112004
[Journal Article] A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures.2014
- Author(s)
  Matsumoto, S., Fujii, S., Sato, A., Ibuka, S., Kagawa, Y., Ishii, M., and Kikuchi, A.
- Journal Title
  
  EMBO J
  
  Volume: 33 Issue: 7 Pages: 702-718
- DOI
  10.1002/embj.201386942
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-24590378, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-25860211, KAKENHI-PROJECT-25861669, KAKENHI-PROJECT-26861547
[Journal Article] Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo.2014
- Author(s)
  Kagawa Y, Matsumoto S, Kamioka Y, Mimori M, Naito Y, Ishii T, Okuzaki D, Nishida N, Maeda S, Naito A, Kikuta J, Nishikawa K, Nishimura J, Haraguchi N, Takemasa I, Mizushima T, Ikeda M, Yamamoto H, Sekimoto M, Ishii H, Doki Y, Matsuda M, Kikuchi A, Mori M, Ishii M
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 12 Pages: e83629-e83629
- DOI
  10.1371/journal.pone.0083629
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22113007, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-23701053, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-25253070, KAKENHI-PROJECT-25860211, KAKENHI-PROJECT-25893117
[Journal Article] Wnt5a signaling promotes apical and basolateral polarization of single epithelial cells.2013
- Author(s)
  Gon, H., Fumoto, K., Ku, Y., Matsumoto, S., and Kikuchi, A.
- Journal Title
  
  Mol. Biol. Cell.
  
  Volume: 24 Issue: 23 Pages: 3764-3774
- DOI
  10.1091/mbc.e13-07-0357
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-24770186, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-25860211
[Journal Article] Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling2012
- Author(s)
  Sakane, H., et.al.
- Journal Title
  
  J.Cell Sci.
  
  Volume: 125 Issue: 2 Pages: 449-460
- DOI
  10.1242/jcs.091876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249017, KAKENHI-PUBLICLY-22019025, KAKENHI-PROJECT-22770127, KAKENHI-PROJECT-22790316, KAKENHI-ORGANIZER-23112001, KAKENHI-PROJECT-23590333, KAKENHI-PROJECT-23650594, KAKENHI-PROJECT-23790333, KAKENHI-PROJECT-24590378, KAKENHI-PLANNED-23112004
[Journal Article] The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility.2012
- Author(s)
  Ishida-Takagishi M, Enomoto A, Asai N, Ushida K, Watanabe T, Hashimoto T, Kato T, Weng L, Matsumoto S, Asai M, Murakumo Y, Kaibuchi K, Kikuchi A, Takahashi M.
- Journal Title
  
  Nat Commun
  
  Volume: 3 Pages: 859-859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790333
[Journal Article] Regulation of focal adhesion dynamics by Wnt5a signaling.2012
- Author(s)
  Matsumoto S, Kikuchi A.
- Journal Title
  
  Methods Mol Biol
  
  Volume: 839 Pages: 215-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790333
[Journal Article] Regulation of focal adhesion dynamics by Wnt5a signaling2012
- Author(s)
  Matsumoto, S., et.al.
- Journal Title
  
  Methods Mol.Biol.
  
  Volume: 839 Pages: 215-27
- DOI
  10.1007/978-1-61779-510-7_17
- ISBN
  9781617795091, 9781617795107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249017, KAKENHI-PROJECT-23650594, KAKENHI-PROJECT-23790333, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004
[Journal Article] An Wnt5a-antibody suppresses metastasis of gastric cancer cells in vivo by inhibiting receptor-mediated endocytosis2012
- Author(s)
  Hanaki, H., et.al.
- Journal Title
  
  Mol.Cancer Ther.
  
  Volume: 11 Issue: 2 Pages: 298-307
- DOI
  10.1158/1535-7163.mct-11-0682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249017, KAKENHI-PUBLICLY-22019025, KAKENHI-PROJECT-22770127, KAKENHI-PROJECT-22790316, KAKENHI-ORGANIZER-23112001, KAKENHI-PROJECT-23590333, KAKENHI-PROJECT-23790333, KAKENHI-PROJECT-24590378, KAKENHI-PLANNED-23112004
[Journal Article] An anti-Wnt5a antibody suppresses metastasis of gastric cancer cells in vivo by inhibiting receptor-mediated endocytosis2012
- Author(s)
  Hanaki H, Yamamoto H, Sakane H, Matsumoto S, Ohdan H, Sato A, and Kikuchi A.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 11 Pages: 298-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790333
[Journal Article] Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling.2012
- Author(s)
  Sakane H, Yamamoto H, Matsumoto S, Sato A, and Kikuchi A.
- Journal Title
  
  J Cell Sci
  
  Volume: 125 Pages: 449-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790333
[Patent] Arl4c遺伝子の発現を抑制する物質又はタンパク質の活性を抑制する物質を含む、癌の治療の為の医薬組成物（核酸を含む）2014
- Inventor(s)
  菊池　章、松本　真司、藤井　慎介
- Industrial Property Rights Holder
  菊池　章、松本　真司、藤井　慎介
- Industrial Property Rights Type
  特許
- Filing Date
  2014-05-13
- Data Source
  KAKENHI-PROJECT-25860211
[Presentation] GREB1によるHNF4αを介したWntシグナル活性化型肝細胞がんの増殖制御機構2022
- Author(s)
  松本真司, 原田昭和, 瀬田みなみ, 権英寿, 福本巧, 菊池章
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H04797
[Presentation] GREB1を軸とした小児固形がん発症シグナルの解明2022
- Author(s)
  原田昭和, 松本真司, 菊池章
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K19407
[Presentation] ホルモン非依存性悪性腫瘍におけるGREB1の発現制御機構2022
- Author(s)
  菊池章, 松本真司, 新澤康英, 原田昭和
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H04797
[Presentation] GREB1を軸とした小児固形がん発症シグナルの解明2022
- Author(s)
  原田昭和, 松本真司, 菊池章
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H04797
[Presentation] GREB1によるHNF4αを介したWntシグナル活性化型肝細胞がんの増殖制御機構2022
- Author(s)
  松本真司, 原田昭和, 瀬田みなみ, 権英寿, 福本巧, 菊池章
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19407
[Presentation] ホルモン非依存性悪性腫瘍におけるGREB1の発現制御機構2022
- Author(s)
  菊池章, 松本真司, 新澤康英, 原田昭和
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19407
[Presentation] 悪性黒色腫におけるMITF依存的なGREB1アイソフォーム4の発現は、ピリミジン合成を介して細胞増殖を促進する2022
- Author(s)
  新澤康英, 松本真司, 佐田遼太, 原田昭和, 種村篤, 二村圭祐, 伊川正人, 曽我朋義, 菊池章
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H04797
[Presentation] GREB1 drives HNF4α-dependent oncogenic transcription and tumor growth in Wnt signal-activated hepatocellular carcinoma.2022
- Author(s)
  Matsumoto S, Harada A, Kikuchi A.
- Organizer
  Wnt Meeting2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04797
[Presentation] GREB1 drives HNF4α-dependent oncogenic transcription and tumor growth in Wnt signal-activated hepatocellular carcinoma.2022
- Author(s)
  Matsumoto S, Harada A, Kikuchi A.
- Organizer
  Wnt Meeting2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19407
[Presentation] GREB1を介する新規がんシグナル経路は分子標的となる2022
- Author(s)
  菊池章, 松本真司, 新澤康英, 佐田遼太, 原田昭和
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H04797
[Presentation] GREB1 isoform 4はピリミジン合成を介して悪性黒色腫細胞の増殖能を促進する2021
- Author(s)
  新澤康英、松本真司、種村篤、横井一範、藤本学、二村圭祐、曽我朋義、菊池章
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19407
[Presentation] Wnt標的遺伝子GREB1の組織特異的発現制御と肝細胞がんの増殖制御機構2021
- Author(s)
  松本真司、瀬田みなみ、福本巧、菊池章
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H04797
[Presentation] RAS下流のエフェクター分子ARL4Cを標的とした膵癌の浸潤転移の制御2021
- Author(s)
  原田昭和、松本真司、菊池章
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H04797
[Presentation] Wnt標的遺伝子GREB1の組織特異的発現制御と肝細胞がんの増殖制御機構2021
- Author(s)
  松本真司、瀬田みなみ、福本巧、菊池章
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K19407
[Presentation] RAS下流のエフェクター分子ARL4Cを標的とした膵癌の浸潤転移の制御2021
- Author(s)
  原田昭和、松本真司、菊池章
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19407
[Presentation] DKK1-CKAP4シグナルは肝癌の予後不良因子であり、CKAP4は新たな治療標的となりうる。2021
- Author(s)
  井口　浩輔、権　英寿、木村　公一、松本　真司、福本　巧、菊池　章
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K07123
[Presentation] Wnt標的遺伝子GREB1の組織特異的発現制御と肝細胞がんの増殖制御機構2021
- Author(s)
  松本真司
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06956
[Presentation] Wnt標的遺伝子GREB1の組織特異的発現制御と肝細胞がんの増殖制御機構2021
- Author(s)
  松本真司
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K07121
[Presentation] GREB1 isoform 4はピリミジン合成を介して悪性黒色腫細胞の増殖能を促進する2021
- Author(s)
  新澤康英、松本真司、種村篤、横井一範、藤本学、二村圭祐、曽我朋義、菊池章
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H04797
[Presentation] 肝細胞がんにおけるWnt標的遺伝子GREB1の発現と細胞増殖制御2020
- Author(s)
  瀬田みなみ, 松本真司, 福本巧, 菊池　章
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06956
[Presentation] Recruitment of KRAS downstream target ARL4C to memblane protrusions accelerates pancreatic cancer cell invasion2020
- Author(s)
  Akikazu Harada, Shinji Matsumoto, Akira Kikuchi
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06956
[Presentation] DKK1-CKAP4 signaling is associated with poor prognosis of HCC and CKAP4 might represent a novel therapeutic target2020
- Author(s)
  Kosuke Iguchi, Hidetoshi Gon, Hirokazu Kimura, Shinji Matsumoto, Takumi Fukumoto, Akira Kikuchi
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06956
[Presentation] パルミトイル化CKAP4はVDAC2を介してミトコンドリア機能を制御する2020
- Author(s)
  原田武志, 佐田遼太, 大杉祥仁, 松本真司, 菊池章
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06956
[Presentation] Wntシグナル標的遺伝子GREB1によるTGFβシグナルの抑制を介した肝芽腫形成の制御2020
- Author(s)
  松本真司, 山道拓, 新沢康英, 奥山宏臣, 菊池章
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06956
[Presentation] 悪性黒色腫におけるGREB1 isoform 4の発現機構解析と治療への応用2020
- Author(s)
  新沢康英, 松本真司, 種村篤, 藤本学, 菊池章
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06956
[Presentation] 唾液腺におけるWntシグナル依存性新規前駆細胞の同定と機能解析2018
- Author(s)
  松本真司
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-15K08272
[Presentation] 唾液腺におけるWntシグナル依存的新規前駆細胞の同定と機能解析2018
- Author(s)
  松本真司
- Organizer
  第91回生化学会大会
- Data Source
  KAKENHI-PROJECT-15K08272
[Presentation] WntとKITシグナルの活性化バランスによる唾液腺の形づくりと機能獲得過程の制御2016
- Author(s)
  松本真司
- Organizer
  歯科基礎医学会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-15K08272
[Presentation] Wnt/β-catenin signaling regulates morphogenesis of embryonic salivary gland through the optimal control of end bud cell acinar formation2015
- Author(s)
  松本真司
- Organizer
  第38回分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K08272
[Presentation] Wnt/β-カテニンシグナルは外分泌腺上皮の分岐と導管形成を制御する2014
- Author(s)
  松本真司
- Organizer
  第87回　日本生化学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25860211
[Presentation] 増殖因子シグナルの協調的作用による上皮管腔形成と腫瘍形成の制御2013
- Author(s)
  菊池章、松本真司、藤井慎介、佐藤朗、井深奏司
- Organizer
  日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PLANNED-23112004
[Presentation] Wnt/β-cateninシグナルとEGFシグナルの協調による三次元基質内での上皮分枝管腔形成制御機構の解析2012
- Author(s)
  松本　真司
- Organizer
  第３５回分子生物学会年会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23790333
[Presentation] Wnt/β-catenin シグナルとEGF シグナルの協調による三次元基質内での上皮分枝管腔形成制御機構の解析2012
- Author(s)
  松本真司
- Organizer
  第35回分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790333
[Presentation] Wnt3a and Wnt5a regulate epithelial polarity and tubulogenesis cooperatively2011
- Author(s)
  松本真司
- Organizer
  第34回分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23790333
[Presentation] Wnt3a and Wnt5a regulate epithelial polarity and tubulogenesis cooperatively2011
- Author(s)
  松本真司
- Organizer
  分子生物学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23790333

1. Kikuchi Akira (10204827)

# of Collaborated Projects: 4 results

# of Collaborated Products: 29 results
2. FUMOTO KATSUMI (40467783)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 権英寿 (70648394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 伊藤智雄 (20301880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 佐田遼太 (60869783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 福本巧 (70379402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. FUJII Shinsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 原田武志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 清島保

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 石井優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsumoto Shinji 松本 真司

MATSUMOTO Shinji 松本 真司

Research Projects

Research Products

Co-Researchers

唾液腺修復における胎生期型先祖返り幹細胞の機能解明と再生医療基盤の構築Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

DKK1/CKAP4シグナルを標的とした肝細胞癌に対する新規抗癌治療の開発

Principal Investigator

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Review Section

Research Institution

Fibroblast remodeling in tumorigenesis based on inflammation

Principal Investigator

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Review Section

Research Institution

Identification of novel tissue-specific stem and progenitor cells responding to Wnt signaling

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

GREB1による小児固形がん発症機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of cell proliferation through interaction between Arl4c and IQGAP1 in pancreatic cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of exocrine glands development by Wnt signalingPrincipal Investigator

Principal Investigator

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Research Institution

Elucidation of the molecular mechanism of the malignant transformation of cancer with the Wnt5a signal and development of the molecular target medicine

Principal Investigator

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Research Institution

Wnt signaling promotes epithelial tubulogenesis through the regulation of cell morphology and proliferationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Spatial regulation of branching tubulogenesis by Wnt signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Moleuclar mechanism for the formation and maintenance of epithelial tubulogenesis with branching

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] G. I. Research「消化管の再生医療」 (In vitro実験系を用いた上皮管腔組織形成の分子基盤の確立)2014

Author(s)

Total Pages

Publisher

Data Source

[Book] Wnt Signaling (Chapter8, Wnt signaling in Development and Disease)2014

Author(s)

Total Pages

Publisher

Matsumoto Shinji 松本真司

MATSUMOTO Shinji 松本真司

[Book] Wnt Signaling　(Chapter8, Wnt signaling in Development and Disease)2014

[Book] Wnt Signaling　(Chapter8, Wnt signaling in Development and Disease)2014

[Book] プログレッシブ生命科学 (細胞増殖・運動・死とがん)2014

[Book] Wnt Signaling　(Chapter8, Wnt signaling in Development and Disease)2014

[Book] 生体の科学　特集　細胞接着の制御2013

[Book] 実験医学増刊　Vol.30 No.52012

[Book] 実験医学増刊　Vol.29 No.22011