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KOSAKA Mituo
小坂 光男
Connect your ORCID iD
*help
Researcher Number
30079983
External Links
Affiliation (Current)
2022: 愛知医科大学, 加齢医科学研究所, その他
Affiliation (based on the past Project Information)
*help
1986 – 1999: 長崎大学, 熱帯医学研究所, 教授
1993 – 1994: Nagasaki Univ., Institute of Tropical Medicine, Prof., 教授
1988: Department of Environmental Physiology Institute of Tropical Medicine, Nagasaki University, 熱医学研究所, 教授
1986: Department of Epidemiology-Environmental Physiology, Institute of Tropical Medicine, Nagasaki University, 熱帯医学研究所, 教授
Review Section/Research Field
Principal Investigator
環境生理学(含体力医学･栄養生理学)
/
Environmental physiology (including Physical medicine and Nutritional physiology)
Except Principal Investigator
環境生理学(含体力医学･栄養生理学)
/
体育学
/
Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords
Principal Investigator
VIP / Hyperthermic Oncology / ナキウサギ / Ionto-phrosis / 熱ショック蛋白(HSPs) / ナキウサギ(pika) / アフガン・ナキウサギ / クチグロ・ナキウサギ / 弱熱耐性 / 高体温
…
More
/ 体温 / 熱ショック蛋白(HSP) / 寒冷ショック蛋白(CSP) / 暑熱順化機序 / HSP 70 / SDS-PAGE / 体温調節機序 / 弱免疫マウス / nude-SCID Mouse / アドレナリン / Method on research for sweating / Human skin transplantation / Catecholamine / QSART (Quantative Sudo-Motor Axon Reflex) / 暑熱 / 寒冷順化 / 視床下部外中枢温度感受性 / 弱熱耐性動物モデル / クチグロ・アフガン・ナキウサギ / SDS-PAGE,Western Blotting / Domestic Animal化 / 高地寒冷・低酸素順化 / 高地体力順化・脳順化機序 / 高地寒冷順化動物 / 温熱パンティング / 温熱性・唾液分泌 / ナキウサギ(pika rabbit) / 高地・寒冷順化動物 / 弱熱放散能 / RVW / LVW / 体温調節 / 温度適応 / 代謝 / 発汗 / 生存温度域 / SDSーPAGE / Cytosol fraction / Western Blotting法 / 寒冷ショック蛋白(CSPs) / Hypertheramic Oncology / HSP70 / 暑熱・寒冷順化機序 / 温熱感受性と耐熱性 / 熱ショック蛋白質(HSPs) / 体温調節反応 / 急性温熱ショック / 慢性温熱ショック / ウサギ・ラット・ナキウサギ / 電気泳動法(10%SDS-PAGE) / heat acclimatization / heat shock proteins (HSPs) / cytosol fraction / western blotting method / cold shock proteins (CSPs) / 温熱感受性 / 温熱耐性 / ニューロ・ペプタイド / サイトカイン / ニューロテンシン / ボンベシン / インターロイキン1αβ / 熱ショック蛋白 / 温度修飾因子 / 熱耐性 / 熱感受性 / 温熱細胞性免疫 / 発熱・解熱 / 寒冷・暑熱適応機序 / SDS-PAGE,Western,Northan blotting / Thermosensitivity / thermotolerance / neuro-peptides / cytokine / neurotensin / Bombesin / IL-1alpha beta / heat shock protein(HSP) / オコト-ナ(学名) / 温度耐性 / 温熱遮断 / 冬眠動物 / テレメータ / 皮膚毛 / テレメトリー / 乳酸値 / 血糖値 / 日内リズム / 行動性体温調節 / 実験動物モデル / Western Blotting / Pika / Ochotna / Thermal insulation / Thermal tolerance / hibernator / Telemetry / Body temperature / Skin hair / 発汗研究法 / ヒト皮膚移植 / カテコールアミン / QSART(Quantative Sudo-Motor Axon Reflex) / アセチール・コリン / VIP(vaso-active intestinal polypeptide) / ピロカルピン / Week immune mouse / 発汗誘発メカニズム / ニコチン作用 / 白血病抑制因子 / ムスカリン作用 / QSART 定量的軸索反射性発汗テスト / イオント・フォレシス(イオン電離輸送) / VIP発汗 / QSART定量的軸索反射性発汗テスト / コリン作動性 / 汗腺交感神経支配 / アセチールコリン / VIP(vasoactive-intestinal peptide) / イオント・フォレーシス / 軸索反射性発汗 / nude-SCID mouse / Weak immune mouse / NMR-MRI / 脳障害ウサギ / アルゴンイオンレーザー / 発熱持性 / 脳局所血流量 / 脳局所代謝 / サーモグラフィー / 発汗誘発潜時 / 発汗連続測定法 / カプセル法 / 温度順化中枢機序 / Heat acclimation / Thermoregulation / Cutaneous vasodilation and- constriction / PO / AH lesion / 暑熱-寒冷順化の形成機序 / 家ウサギ / ヒト(スポーツ選手) / LPS / IL_1-α / IL_1-β / 発熱特性 / 熱放散反応解析 / 甲状腺ホルモン / 発汗測定 / 暑熱-運動の交叉適応 / 甲状腺機能亢進 / 低下症 / 脳血流 / 甲状腺ホルモン測定 / アルゴンレーザー / 水素クリアランス法 / 温度順化 / 体温調節熱放散能 / 外因性・内因性発熱物質 / 熱帯地非スポーツマン / 日本人運動選手 / 暑熱ー運動の交叉適応 / Pika (Whistle rabbit) / albino rabbit / tropical subject / sportsmen / heat-and cold-acclimated rabbit / pyrogenicity / poor heat loss ability / cerebral blood flow / thermal sweating thyroid hormone / heat-exercise cross adaptation
…
More
Except Principal Investigator
ハイパーサーミア / 癌治療 / 熱耐性 / 高地適応動物モデル / 温熱処理 / 細胞致死 / 体温調節 / 高原ナキウサギ / 中国小型ブタ / Highland pika / Animal models for high altitude adaptation / Hyperthermia Oncology / Thermochemotherapy / Thermotolerance / Murine Experimental Tumor / In Vitro Cell Culture / ミトコンドリア / 放射線照射 / 化学療法 / 温熱療法 / 加熱処理 / 温熱増感効果 / ナキウサギ / クチグロナキウサギ / 高地動物モデル / 中国青海省 / 実験動物 / Pike / Ochotona curzoniae / High-altitude animal model / Tsinghai province in China / Laboratory animals / 環境適応 / 免疫サイトカイン / 体液 / 循環 / 生体リズム / Environment / Adaptation / Body temperature / Circulation / Body fluid / Immune response / Circadian rhythm / Behavior / チベット高原ナキウサギ / ネパールナキウサギ / Highland pika in Tibet / Pika in Nepal / 食細胞 / Bリンパ球 / 活性酸素 / シトクロムb558 / 慢性肉芽腫症 / 活性酸素産生 / Superoxide-Generating System / Phagocytes / B Lymphocytes / Chronic granulomatoous disease / Cytochrome b558 / モンゴルのナキウサギ / ダウリナキウサギ / Ochotona daurica / Pika in Mongolia / Miniature pigs / 汗拍出頻度 / 暑熱順化 / 運動鍛練 / 皮膚血流量 / 酸素摂取量 / 運動鍛錬 / 発汗の拍出頻度 / 酸素消費量 / Frequency of sweat expulsions / Heat adaptation / Physical training / Oxygen consumption / 環境生理学 / 紫外線影響 / 紫外線防御 / 紫外線透過率 / 皮膚障害 / 野生哺乳動物 / 環境因子 / 環境生物学 / 紫外線 / 組織変性 / マウス / 細胞免疫 / 液性免疫 / Environmental biology / Wild mammals / Ultraviolet rays (UV) / Defense to UV / Dermatopathy by UV / Transmission rate of UV / 高齢者 / 暑熱適応 / 体温 / 発汗機能 / 循環機能 / 体熱出納 / 体力 / 概日リズム / 日周変動 / 季節差 / 運動能力 / 皮膚血流 / 栄養 / 体温調節機能 / 基礎代謝 / 発汗 / 汗腺訓練 / aging / heat adaptation / body temperature / sweating function / circulatory function / heat balance / fitness
Less
Research Projects
(
21
results)
Co-Researchers
(
52
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Ultraviolet permeability through skin of wild animals and skin degeneration by ultraviolet rays
Principal Investigator
OHWATARI Nobu
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
Institute of Tropical Medicine, Nagasaki University
Analysis of sweating of human skin transplanted on the weak immune mouse
Principal Investigator
Principal Investigator
KOSAKA Mitsuo
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
Institute of Tropical Medicine, Nagasaki University
Initial Fine Control Mechanism of Sweating in Well-Trained Athletes
Principal Investigator
YAMAUCHI Masaki
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
体育学
Research Institution
Nagasaki University
Study on sweating from xenotransplanted human skin
Principal Investigator
Principal Investigator
KOSAKA Mitsuo
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
Nagasaki University
温度ストレス環境適応能力開発に関する温熱生理学的方策
Principal Investigator
Principal Investigator
小坂 光男
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Nagasaki University
Study on various species of Pikas indigenous to high altitude -Pikas as animal modeis for high altitude adaptation-
Principal Investigator
SAITO Muneo
, 斉藤 宗雄
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Central Institute for Experimental Animals
Basic research on development of experimental animal model for weak heat tolerance and bbehavioral thermoregulation
Principal Investigator
Principal Investigator
KOSAKA Mitsuo
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Environmental physiology (including Physical medicine and Nutritional physiology)
Research Institution
Nagasaki University
Generation and Role of Active oxygens in Cells
Principal Investigator
NAKAMURA Michio
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Institute of Tropical Medicine, Nagasaki University
Study on Pika(Ochtona) as Animal Models for High Altitude Adaptation
Principal Investigator
NOMURA Tatsuji
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Central Institute for Experimental Animals
Research project on the varient modification of thermosensitivity in the
Principal Investigator
Principal Investigator
KOSAKA Mitsuo
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
Institute of Tropical Medicine, Nagasaki University
温熱と制がん剤の併用効果及びその臨床応用に関する基礎的研究
Principal Investigator
KANO Eiichi
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
福井医科大学
弱熱耐性動物モデルとしてナキウサギ(PiKa)開発の基礎研究
Principal Investigator
Principal Investigator
小坂 光男
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
Nagasaki University
Integrative analysis of physiological adaption to environmental stress.
Principal Investigator
MORIMOTO T.
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
Kyoto Prefectural University of Medicine
Research on Pika (Ochotona) as high altitude animal models
Principal Investigator
NOMURA Tatuji
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Centoral Institute for Experimental Animals
Induction of Heat Shock Proteins (HSPs) in the Process of Heat Tolerance
Principal Investigator
Principal Investigator
KOSAKA Mitsuo
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
Institute of Tropical Medicine, Nagasaki University
動物腫瘍系における温熱の制癌効果を左右する因子とその修飾に関する研究
Principal Investigator
奥村 寛
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagasaki University
動物腫瘍系における温熱の制癌効果を左右する因子とその修飾に関する研究
Principal Investigator
奥村 寛
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagasaki University
Analysis of thermoregulatory and pyretic responses in heat-and cold-acclimation
Principal Investigator
Principal Investigator
KOSAKA Mitsuo
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
Institute of Tropical Medicine, Nagasaki University
動物腫瘍系における温熱の制癌効果を左右する因子とその修飾に関する研究
Principal Investigator
OKUMURA Yutaka
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagasaki University
Heat adaptation in the aged
Principal Investigator
OGAWA Tokuo
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
Aichi Medical University
Analysis of thermoregulatory responses in the process of heat-and cold-acclimatization
Principal Investigator
Principal Investigator
KOSAKA Mitsuo
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
環境生理学(含体力医学･栄養生理学)
Research Institution
Institute of Tropical Medicine, Nagasaki University
# of Projects (Dsc)
# of Projects (Asc)
1.
OHWATARI Nobu
(80128165)
# of Collaborated Projects:
10 results
# of Collaborated Products:
0 results
2.
SAITOU Muneo
(50167417)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
3.
MATSUMOTO Takaaki.
(60199875)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
4.
KANO Eiichi
(70065910)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
5.
SAKAI Akio
(70020758)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
6.
MATUZAKI Tetuya
(30167647)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
7.
YAMASHITA Shunichi
(30200679)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
8.
OKUMURA Yutaka
(00073130)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
9.
土屋 勝彦
(90073006)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
10.
NOMURA Tatuji
(10072399)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
11.
川崎 祥二
(20034952)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
12.
田中 紀元
(20079932)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
13.
MORIMOTO T.
(30079694)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
IRIKI M.
(90072967)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
KUROSHIMA A.
(90002774)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
KUMATORI Atsushi
(60244092)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
NAGASAKA Tetsuo
(80023646)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
18.
NAKAMURA Michio
(30091276)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
19.
KANEDA Eiko
(10253626)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
20.
中村 弥
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
21.
KAWATA M.
(60112512)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
ONO T.
(50019577)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
ITAKURA Hideyo
(00010512)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
NAGATAKE Tsuyoshi
(30164445)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
HIRAYAMA Toshiya
(50050696)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
KANBARA Hiroji
(20029789)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
YAMAUCHI Masaki
(00128232)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
TORIYAMA Kan
(00108359)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
FUJIMAKI Yasunori
(10209083)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
FUJIWARA Mariko
(50156931)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
IWAMOTO Jun
(20160137)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
OGAWA Tokuo
(50065520)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
NAKAYAMA Teruo
(80022763)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
SASAKI Susumu
(00022682)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
SHIRAKI Keizo
(00035453)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
MATSUO Sachiko
(80039916)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
中島 俊文
(30155725)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
馬嶋 秀行
(60165701)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
前田 迪郎
(70032208)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
大西 武雄
(60094554)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
柳平 担徳
(10020760)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
42.
広重 力
(50000914)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
43.
村上 悳
(90040518)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
44.
中村 彌
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
45.
RADEKE H.H.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
46.
VERHOEVEN AJ
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
47.
JONES O.T.G.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
48.
OTG Jones
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
49.
HH Radeke
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
50.
AJ Verhoeven
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
51.
RADEKE H
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
52.
JONES OTG
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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