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KOSAKA Mituo  小坂 光男

ORCIDConnect your ORCID iD *help
Researcher Number 30079983
External Links
Affiliation (Current) 2022: 愛知医科大学, 加齢医科学研究所, その他
Affiliation (based on the past Project Information) *help 1986 – 1999: 長崎大学, 熱帯医学研究所, 教授
1993 – 1994: Nagasaki Univ., Institute of Tropical Medicine, Prof., 教授
1988: Department of Environmental Physiology Institute of Tropical Medicine, Nagasaki University, 熱医学研究所, 教授
1986: Department of Epidemiology-Environmental Physiology, Institute of Tropical Medicine, Nagasaki University, 熱帯医学研究所, 教授
Review Section/Research Field
Principal Investigator
環境生理学(含体力医学・栄養生理学) / Environmental physiology (including Physical medicine and Nutritional physiology)
Except Principal Investigator
環境生理学(含体力医学・栄養生理学) / 体育学 / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords
Principal Investigator
VIP / Hyperthermic Oncology / ナキウサギ / Ionto-phrosis / 熱ショック蛋白(HSPs) / ナキウサギ(pika) / アフガン・ナキウサギ / クチグロ・ナキウサギ / 弱熱耐性 / 高体温 … More / 体温 / 熱ショック蛋白(HSP) / 寒冷ショック蛋白(CSP) / 暑熱順化機序 / HSP 70 / SDS-PAGE / 体温調節機序 / 弱免疫マウス / nude-SCID Mouse / アドレナリン / Method on research for sweating / Human skin transplantation / Catecholamine / QSART (Quantative Sudo-Motor Axon Reflex) / 暑熱 / 寒冷順化 / 視床下部外中枢温度感受性 / 弱熱耐性動物モデル / クチグロ・アフガン・ナキウサギ / SDS-PAGE,Western Blotting / Domestic Animal化 / 高地寒冷・低酸素順化 / 高地体力順化・脳順化機序 / 高地寒冷順化動物 / 温熱パンティング / 温熱性・唾液分泌 / ナキウサギ(pika rabbit) / 高地・寒冷順化動物 / 弱熱放散能 / RVW / LVW / 体温調節 / 温度適応 / 代謝 / 発汗 / 生存温度域 / SDSーPAGE / Cytosol fraction / Western Blotting法 / 寒冷ショック蛋白(CSPs) / Hypertheramic Oncology / HSP70 / 暑熱・寒冷順化機序 / 温熱感受性と耐熱性 / 熱ショック蛋白質(HSPs) / 体温調節反応 / 急性温熱ショック / 慢性温熱ショック / ウサギ・ラット・ナキウサギ / 電気泳動法(10%SDS-PAGE) / heat acclimatization / heat shock proteins (HSPs) / cytosol fraction / western blotting method / cold shock proteins (CSPs) / 温熱感受性 / 温熱耐性 / ニューロ・ペプタイド / サイトカイン / ニューロテンシン / ボンベシン / インターロイキン1αβ / 熱ショック蛋白 / 温度修飾因子 / 熱耐性 / 熱感受性 / 温熱細胞性免疫 / 発熱・解熱 / 寒冷・暑熱適応機序 / SDS-PAGE,Western,Northan blotting / Thermosensitivity / thermotolerance / neuro-peptides / cytokine / neurotensin / Bombesin / IL-1alpha beta / heat shock protein(HSP) / オコト-ナ(学名) / 温度耐性 / 温熱遮断 / 冬眠動物 / テレメータ / 皮膚毛 / テレメトリー / 乳酸値 / 血糖値 / 日内リズム / 行動性体温調節 / 実験動物モデル / Western Blotting / Pika / Ochotna / Thermal insulation / Thermal tolerance / hibernator / Telemetry / Body temperature / Skin hair / 発汗研究法 / ヒト皮膚移植 / カテコールアミン / QSART(Quantative Sudo-Motor Axon Reflex) / アセチール・コリン / VIP(vaso-active intestinal polypeptide) / ピロカルピン / Week immune mouse / 発汗誘発メカニズム / ニコチン作用 / 白血病抑制因子 / ムスカリン作用 / QSART 定量的軸索反射性発汗テスト / イオント・フォレシス(イオン電離輸送) / VIP発汗 / QSART定量的軸索反射性発汗テスト / コリン作動性 / 汗腺交感神経支配 / アセチールコリン / VIP(vasoactive-intestinal peptide) / イオント・フォレーシス / 軸索反射性発汗 / nude-SCID mouse / Weak immune mouse / NMR-MRI / 脳障害ウサギ / アルゴンイオンレーザー / 発熱持性 / 脳局所血流量 / 脳局所代謝 / サーモグラフィー / 発汗誘発潜時 / 発汗連続測定法 / カプセル法 / 温度順化中枢機序 / Heat acclimation / Thermoregulation / Cutaneous vasodilation and- constriction / PO / AH lesion / 暑熱-寒冷順化の形成機序 / 家ウサギ / ヒト(スポーツ選手) / LPS / IL_1-α / IL_1-β / 発熱特性 / 熱放散反応解析 / 甲状腺ホルモン / 発汗測定 / 暑熱-運動の交叉適応 / 甲状腺機能亢進 / 低下症 / 脳血流 / 甲状腺ホルモン測定 / アルゴンレーザー / 水素クリアランス法 / 温度順化 / 体温調節熱放散能 / 外因性・内因性発熱物質 / 熱帯地非スポーツマン / 日本人運動選手 / 暑熱ー運動の交叉適応 / Pika (Whistle rabbit) / albino rabbit / tropical subject / sportsmen / heat-and cold-acclimated rabbit / pyrogenicity / poor heat loss ability / cerebral blood flow / thermal sweating thyroid hormone / heat-exercise cross adaptation … More
Except Principal Investigator
ハイパーサーミア / 癌治療 / 熱耐性 / 高地適応動物モデル / 温熱処理 / 細胞致死 / 体温調節 / 高原ナキウサギ / 中国小型ブタ / Highland pika / Animal models for high altitude adaptation / Hyperthermia Oncology / Thermochemotherapy / Thermotolerance / Murine Experimental Tumor / In Vitro Cell Culture / ミトコンドリア / 放射線照射 / 化学療法 / 温熱療法 / 加熱処理 / 温熱増感効果 / ナキウサギ / クチグロナキウサギ / 高地動物モデル / 中国青海省 / 実験動物 / Pike / Ochotona curzoniae / High-altitude animal model / Tsinghai province in China / Laboratory animals / 環境適応 / 免疫サイトカイン / 体液 / 循環 / 生体リズム / Environment / Adaptation / Body temperature / Circulation / Body fluid / Immune response / Circadian rhythm / Behavior / チベット高原ナキウサギ / ネパールナキウサギ / Highland pika in Tibet / Pika in Nepal / 食細胞 / Bリンパ球 / 活性酸素 / シトクロムb558 / 慢性肉芽腫症 / 活性酸素産生 / Superoxide-Generating System / Phagocytes / B Lymphocytes / Chronic granulomatoous disease / Cytochrome b558 / モンゴルのナキウサギ / ダウリナキウサギ / Ochotona daurica / Pika in Mongolia / Miniature pigs / 汗拍出頻度 / 暑熱順化 / 運動鍛練 / 皮膚血流量 / 酸素摂取量 / 運動鍛錬 / 発汗の拍出頻度 / 酸素消費量 / Frequency of sweat expulsions / Heat adaptation / Physical training / Oxygen consumption / 環境生理学 / 紫外線影響 / 紫外線防御 / 紫外線透過率 / 皮膚障害 / 野生哺乳動物 / 環境因子 / 環境生物学 / 紫外線 / 組織変性 / マウス / 細胞免疫 / 液性免疫 / Environmental biology / Wild mammals / Ultraviolet rays (UV) / Defense to UV / Dermatopathy by UV / Transmission rate of UV / 高齢者 / 暑熱適応 / 体温 / 発汗機能 / 循環機能 / 体熱出納 / 体力 / 概日リズム / 日周変動 / 季節差 / 運動能力 / 皮膚血流 / 栄養 / 体温調節機能 / 基礎代謝 / 発汗 / 汗腺訓練 / aging / heat adaptation / body temperature / sweating function / circulatory function / heat balance / fitness Less
  • Research Projects

    (21 results)
  • Co-Researchers

    (52 People)
  •  Ultraviolet permeability through skin of wild animals and skin degeneration by ultraviolet rays

    • Principal Investigator
      OHWATARI Nobu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  Analysis of sweating of human skin transplanted on the weak immune mousePrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  Initial Fine Control Mechanism of Sweating in Well-Trained Athletes

    • Principal Investigator
      YAMAUCHI Masaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      体育学
    • Research Institution
      Nagasaki University
  •  Study on sweating from xenotransplanted human skinPrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Nagasaki University
  •  温度ストレス環境適応能力開発に関する温熱生理学的方策Principal Investigator

    • Principal Investigator
      小坂 光男
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagasaki University
  •  Study on various species of Pikas indigenous to high altitude -Pikas as animal modeis for high altitude adaptation-

    • Principal Investigator
      SAITO Muneo, 斉藤 宗雄
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Central Institute for Experimental Animals
  •  Basic research on development of experimental animal model for weak heat tolerance and bbehavioral thermoregulationPrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Nagasaki University
  •  Generation and Role of Active oxygens in Cells

    • Principal Investigator
      NAKAMURA Michio
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  Study on Pika(Ochtona) as Animal Models for High Altitude Adaptation

    • Principal Investigator
      NOMURA Tatsuji
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Central Institute for Experimental Animals
  •  Research project on the varient modification of thermosensitivity in thePrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  温熱と制がん剤の併用効果及びその臨床応用に関する基礎的研究

    • Principal Investigator
      KANO Eiichi
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      福井医科大学
  •  弱熱耐性動物モデルとしてナキウサギ(PiKa)開発の基礎研究Principal Investigator

    • Principal Investigator
      小坂 光男
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Nagasaki University
  •  Integrative analysis of physiological adaption to environmental stress.

    • Principal Investigator
      MORIMOTO T.
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Research on Pika (Ochotona) as high altitude animal models

    • Principal Investigator
      NOMURA Tatuji
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Centoral Institute for Experimental Animals
  •  Induction of Heat Shock Proteins (HSPs) in the Process of Heat TolerancePrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  動物腫瘍系における温熱の制癌効果を左右する因子とその修飾に関する研究

    • Principal Investigator
      奥村 寛
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagasaki University
  •  動物腫瘍系における温熱の制癌効果を左右する因子とその修飾に関する研究

    • Principal Investigator
      奥村 寛
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagasaki University
  •  Analysis of thermoregulatory and pyretic responses in heat-and cold-acclimationPrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  動物腫瘍系における温熱の制癌効果を左右する因子とその修飾に関する研究

    • Principal Investigator
      OKUMURA Yutaka
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagasaki University
  •  Heat adaptation in the aged

    • Principal Investigator
      OGAWA Tokuo
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Aichi Medical University
  •  Analysis of thermoregulatory responses in the process of heat-and cold-acclimatizationPrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  • 1.  OHWATARI Nobu (80128165)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  SAITOU Muneo (50167417)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  MATSUMOTO Takaaki. (60199875)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  KANO Eiichi (70065910)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  SAKAI Akio (70020758)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  MATUZAKI Tetuya (30167647)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  YAMASHITA Shunichi (30200679)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  OKUMURA Yutaka (00073130)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  土屋 勝彦 (90073006)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  NOMURA Tatuji (10072399)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  川崎 祥二 (20034952)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  田中 紀元 (20079932)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  MORIMOTO T. (30079694)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  IRIKI M. (90072967)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  KUROSHIMA A. (90002774)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  KUMATORI Atsushi (60244092)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  NAGASAKA Tetsuo (80023646)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  NAKAMURA Michio (30091276)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  KANEDA Eiko (10253626)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  中村 弥
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  KAWATA M. (60112512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  ONO T. (50019577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  ITAKURA Hideyo (00010512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  NAGATAKE Tsuyoshi (30164445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  HIRAYAMA Toshiya (50050696)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  KANBARA Hiroji (20029789)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  YAMAUCHI Masaki (00128232)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  TORIYAMA Kan (00108359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  FUJIMAKI Yasunori (10209083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  FUJIWARA Mariko (50156931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  IWAMOTO Jun (20160137)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  OGAWA Tokuo (50065520)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  NAKAYAMA Teruo (80022763)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  SASAKI Susumu (00022682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  SHIRAKI Keizo (00035453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  MATSUO Sachiko (80039916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  中島 俊文 (30155725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  馬嶋 秀行 (60165701)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  前田 迪郎 (70032208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  大西 武雄 (60094554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  柳平 担徳 (10020760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  広重 力 (50000914)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  村上 悳 (90040518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  中村 彌
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  RADEKE H.H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  VERHOEVEN AJ
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  JONES O.T.G.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  OTG Jones
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  HH Radeke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  AJ Verhoeven
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  RADEKE H
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  JONES OTG
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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