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KOSAKA Mituo  小坂 光男

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… Alternative Names

小坂 光男  コサカ ミツオ

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Researcher Number 30079983
External Links
Affiliation (Current) 2025: 愛知医科大学, 加齢医科学研究所, その他
Affiliation (based on the past Project Information) *help 1986 – 1999: 長崎大学, 熱帯医学研究所, 教授
1993 – 1994: Nagasaki Univ., Institute of Tropical Medicine, Prof., 教授
1988: Department of Environmental Physiology Institute of Tropical Medicine, Nagasaki University, 熱医学研究所, 教授
1986: Department of Epidemiology-Environmental Physiology, Institute of Tropical Medicine, Nagasaki University, 熱帯医学研究所, 教授
Review Section/Research Field
Principal Investigator
環境生理学(含体力医学・栄養生理学) / Environmental physiology (including Physical medicine and Nutritional physiology)
Except Principal Investigator
環境生理学(含体力医学・栄養生理学) / Environmental physiology (including Physical medicine and Nutritional physiology) / 体育学
Keywords
Principal Investigator
VIP / Ionto-phrosis / ナキウサギ / Hyperthermic Oncology / 視床下部外中枢温度感受性 / 寒冷順化 / 暑熱 / QSART (Quantative Sudo-Motor Axon Reflex) / Catecholamine / Human skin transplantation … More / Method on research for sweating / アドレナリン / nude-SCID Mouse / 弱免疫マウス / 体温調節機序 / SDS-PAGE / HSP 70 / 暑熱順化機序 / 寒冷ショック蛋白(CSP) / 熱ショック蛋白(HSP) / 体温 / 高体温 / 弱熱耐性 / クチグロ・ナキウサギ / アフガン・ナキウサギ / ナキウサギ(pika) / 熱ショック蛋白(HSPs) / heat-exercise cross adaptation / thermal sweating thyroid hormone / cerebral blood flow / poor heat loss ability / pyrogenicity / heat-and cold-acclimated rabbit / sportsmen / tropical subject / albino rabbit / Pika (Whistle rabbit) / 暑熱ー運動の交叉適応 / 日本人運動選手 / 熱帯地非スポーツマン / 外因性・内因性発熱物質 / 体温調節熱放散能 / 温度順化 / 水素クリアランス法 / アルゴンレーザー / 甲状腺ホルモン測定 / 脳血流 / 低下症 / 甲状腺機能亢進 / 暑熱-運動の交叉適応 / 発汗測定 / 甲状腺ホルモン / 熱放散反応解析 / 発熱特性 / IL_1-β / IL_1-α / LPS / ヒト(スポーツ選手) / 家ウサギ / 暑熱-寒冷順化の形成機序 / AH lesion / PO / Cutaneous vasodilation and- constriction / Thermoregulation / Heat acclimation / 温度順化中枢機序 / カプセル法 / 発汗連続測定法 / 発汗誘発潜時 / サーモグラフィー / 脳局所代謝 / 脳局所血流量 / 発熱持性 / アルゴンイオンレーザー / 脳障害ウサギ / NMR-MRI / Weak immune mouse / nude-SCID mouse / 軸索反射性発汗 / イオント・フォレーシス / VIP(vasoactive-intestinal peptide) / アセチールコリン / 汗腺交感神経支配 / コリン作動性 / QSART定量的軸索反射性発汗テスト / VIP発汗 / イオント・フォレシス(イオン電離輸送) / QSART 定量的軸索反射性発汗テスト / ムスカリン作用 / 白血病抑制因子 / ニコチン作用 / 発汗誘発メカニズム / Week immune mouse / ピロカルピン / VIP(vaso-active intestinal polypeptide) / アセチール・コリン / QSART(Quantative Sudo-Motor Axon Reflex) / カテコールアミン / ヒト皮膚移植 / 発汗研究法 / Skin hair / Body temperature / Telemetry / hibernator / Thermal tolerance / Thermal insulation / Ochotna / Pika / Western Blotting / 実験動物モデル / 行動性体温調節 / 日内リズム / 血糖値 / 乳酸値 / テレメトリー / 皮膚毛 / テレメータ / 冬眠動物 / 温熱遮断 / 温度耐性 / オコト-ナ(学名) / heat shock protein(HSP) / IL-1alpha beta / Bombesin / neurotensin / cytokine / neuro-peptides / thermotolerance / Thermosensitivity / SDS-PAGE,Western,Northan blotting / 寒冷・暑熱適応機序 / 発熱・解熱 / 温熱細胞性免疫 / 熱感受性 / 熱耐性 / 温度修飾因子 / 熱ショック蛋白 / インターロイキン1αβ / ボンベシン / ニューロテンシン / サイトカイン / ニューロ・ペプタイド / 温熱耐性 / 温熱感受性 / cold shock proteins (CSPs) / western blotting method / cytosol fraction / heat shock proteins (HSPs) / heat acclimatization / 電気泳動法(10%SDS-PAGE) / ウサギ・ラット・ナキウサギ / 慢性温熱ショック / 急性温熱ショック / 体温調節反応 / 熱ショック蛋白質(HSPs) / 温熱感受性と耐熱性 / 暑熱・寒冷順化機序 / HSP70 / Hypertheramic Oncology / 寒冷ショック蛋白(CSPs) / Western Blotting法 / Cytosol fraction / SDSーPAGE / 生存温度域 / 発汗 / 代謝 / 温度適応 / 体温調節 / LVW / RVW / 弱熱放散能 / 高地・寒冷順化動物 / ナキウサギ(pika rabbit) / 温熱性・唾液分泌 / 温熱パンティング / 高地寒冷順化動物 / 高地体力順化・脳順化機序 / 高地寒冷・低酸素順化 / Domestic Animal化 / SDS-PAGE,Western Blotting / クチグロ・アフガン・ナキウサギ / 弱熱耐性動物モデル … More
Except Principal Investigator
高地適応動物モデル / 熱耐性 / 癌治療 / ハイパーサーミア / Animal models for high altitude adaptation / Highland pika / 中国小型ブタ / 高原ナキウサギ / 体温調節 / 細胞致死 / 温熱処理 / fitness / heat balance / circulatory function / sweating function / body temperature / heat adaptation / aging / 汗腺訓練 / 発汗 / 基礎代謝 / 体温調節機能 / 栄養 / 皮膚血流 / 運動能力 / 季節差 / 日周変動 / 概日リズム / 体力 / 体熱出納 / 循環機能 / 発汗機能 / 体温 / 暑熱適応 / 高齢者 / Transmission rate of UV / Dermatopathy by UV / Defense to UV / Ultraviolet rays (UV) / Wild mammals / Environmental biology / 液性免疫 / 細胞免疫 / マウス / 組織変性 / 紫外線 / 環境生物学 / 環境因子 / 野生哺乳動物 / 皮膚障害 / 紫外線透過率 / 紫外線防御 / 紫外線影響 / 環境生理学 / Oxygen consumption / Physical training / Heat adaptation / Frequency of sweat expulsions / 酸素消費量 / 発汗の拍出頻度 / 運動鍛錬 / 酸素摂取量 / 皮膚血流量 / 運動鍛練 / 暑熱順化 / 汗拍出頻度 / Miniature pigs / Pika in Mongolia / Ochotona daurica / ダウリナキウサギ / モンゴルのナキウサギ / Cytochrome b558 / Chronic granulomatoous disease / B Lymphocytes / Phagocytes / Superoxide-Generating System / 活性酸素産生 / 慢性肉芽腫症 / シトクロムb558 / 活性酸素 / Bリンパ球 / 食細胞 / Pika in Nepal / Highland pika in Tibet / ネパールナキウサギ / チベット高原ナキウサギ / Behavior / Circadian rhythm / Immune response / Body fluid / Circulation / Body temperature / Adaptation / Environment / 生体リズム / 循環 / 体液 / 免疫サイトカイン / 環境適応 / Laboratory animals / Tsinghai province in China / High-altitude animal model / Ochotona curzoniae / Pike / 実験動物 / 中国青海省 / 高地動物モデル / クチグロナキウサギ / ナキウサギ / 温熱増感効果 / 加熱処理 / 温熱療法 / 化学療法 / 放射線照射 / ミトコンドリア / In Vitro Cell Culture / Murine Experimental Tumor / Thermotolerance / Thermochemotherapy / Hyperthermia Oncology Less
  • Research Projects

    (21 results)
  • Co-Researchers

    (52 People)
  •  Ultraviolet permeability through skin of wild animals and skin degeneration by ultraviolet rays

    • Principal Investigator
      OHWATARI Nobu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  Analysis of sweating of human skin transplanted on the weak immune mousePrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  Initial Fine Control Mechanism of Sweating in Well-Trained Athletes

    • Principal Investigator
      YAMAUCHI Masaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      体育学
    • Research Institution
      Nagasaki University
  •  Study on sweating from xenotransplanted human skinPrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Nagasaki University
  •  温度ストレス環境適応能力開発に関する温熱生理学的方策Principal Investigator

    • Principal Investigator
      小坂 光男
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagasaki University
  •  Study on various species of Pikas indigenous to high altitude -Pikas as animal modeis for high altitude adaptation-

    • Principal Investigator
      SAITO Muneo, 斉藤 宗雄
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Central Institute for Experimental Animals
  •  Basic research on development of experimental animal model for weak heat tolerance and bbehavioral thermoregulationPrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Nagasaki University
  •  Generation and Role of Active oxygens in Cells

    • Principal Investigator
      NAKAMURA Michio
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  Study on Pika(Ochtona) as Animal Models for High Altitude Adaptation

    • Principal Investigator
      NOMURA Tatsuji
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Central Institute for Experimental Animals
  •  Research project on the varient modification of thermosensitivity in thePrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  温熱と制がん剤の併用効果及びその臨床応用に関する基礎的研究

    • Principal Investigator
      KANO Eiichi
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      福井医科大学
  •  弱熱耐性動物モデルとしてナキウサギ(PiKa)開発の基礎研究Principal Investigator

    • Principal Investigator
      小坂 光男
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Nagasaki University
  •  Integrative analysis of physiological adaption to environmental stress.

    • Principal Investigator
      MORIMOTO T.
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Research on Pika (Ochotona) as high altitude animal models

    • Principal Investigator
      NOMURA Tatuji
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Centoral Institute for Experimental Animals
  •  Induction of Heat Shock Proteins (HSPs) in the Process of Heat TolerancePrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  動物腫瘍系における温熱の制癌効果を左右する因子とその修飾に関する研究

    • Principal Investigator
      奥村 寛
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagasaki University
  •  動物腫瘍系における温熱の制癌効果を左右する因子とその修飾に関する研究

    • Principal Investigator
      奥村 寛
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagasaki University
  •  Analysis of thermoregulatory and pyretic responses in heat-and cold-acclimationPrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  •  動物腫瘍系における温熱の制癌効果を左右する因子とその修飾に関する研究

    • Principal Investigator
      OKUMURA Yutaka
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagasaki University
  •  Heat adaptation in the aged

    • Principal Investigator
      OGAWA Tokuo
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Aichi Medical University
  •  Analysis of thermoregulatory responses in the process of heat-and cold-acclimatizationPrincipal Investigator

    • Principal Investigator
      KOSAKA Mitsuo
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Institute of Tropical Medicine, Nagasaki University
  • 1.  OHWATARI Nobu (80128165)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  SAITOU Muneo (50167417)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  MATSUMOTO Takaaki. (60199875)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  KANO Eiichi (70065910)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  SAKAI Akio (70020758)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  MATUZAKI Tetuya (30167647)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  YAMASHITA Shunichi (30200679)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  OKUMURA Yutaka (00073130)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  土屋 勝彦 (90073006)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  NOMURA Tatuji (10072399)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  川崎 祥二 (20034952)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  田中 紀元 (20079932)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  MORIMOTO T. (30079694)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  IRIKI M. (90072967)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  KUROSHIMA A. (90002774)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  KUMATORI Atsushi (60244092)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  NAGASAKA Tetsuo (80023646)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  NAKAMURA Michio (30091276)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  KANEDA Eiko (10253626)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  中村 弥
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  KAWATA M. (60112512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  ONO T. (50019577)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  ITAKURA Hideyo (00010512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  NAGATAKE Tsuyoshi (30164445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  HIRAYAMA Toshiya (50050696)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  KANBARA Hiroji (20029789)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  YAMAUCHI Masaki (00128232)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  TORIYAMA Kan (00108359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  FUJIMAKI Yasunori (10209083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  FUJIWARA Mariko (50156931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  IWAMOTO Jun (20160137)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  OGAWA Tokuo (50065520)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  NAKAYAMA Teruo (80022763)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  SASAKI Susumu (00022682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  SHIRAKI Keizo (00035453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  MATSUO Sachiko (80039916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  中島 俊文 (30155725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  馬嶋 秀行 (60165701)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  前田 迪郎 (70032208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  大西 武雄 (60094554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  柳平 担徳 (10020760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  広重 力 (50000914)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  村上 悳 (90040518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  中村 彌
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  RADEKE H.H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  VERHOEVEN AJ
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  JONES O.T.G.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  OTG Jones
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  HH Radeke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  AJ Verhoeven
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  RADEKE H
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  JONES OTG
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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