ADACHI Isao 足立伊左雄

… Alternative Names

ADACH Isaso 足立伊左雄

足立伊左雄アダチイサオ

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Researcher Number	30151070
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2019: 富山大学, 学術研究部薬学・和漢系, 教授 2016 – 2018: 富山大学, 附属病院, 教授 2009 – 2015: 富山大学, 大学病院, 教授 2002 – 2003: 富山医科薬科大学, 附属病院, 教授 2001: 富山医科薬科大学, 付属病院, 教授 … More 1998 – 2000: 富山医科薬科大学, 附属病院, 教授 1995 – 1996: 富山医科薬科大学, 附属病院, 助教授 1990: 富山医科薬科大学, 附属病院, 助教授 1987 – 1988: Department of Hospital Pharmacy, Toyama Medical & Pharmaceutical University, Res, 附属病院, 助手 1987: Department of Hospital Pharmacy, Toyama Medical & Pharmaceutical University, Res, 付属病院, 助手 1986: 富山医薬大, 附属病院・薬剤部, 助手 1986: 富山医薬大, 附属病院薬剤部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Drug development chemistry Except Principal Investigator Physical pharmacy / Drug development chemistry / Science and Engineering / Chemical pharmacy / Biomedical engineering/Biological material science
Keywords	Principal Investigator イミノ糖 / グリコシダーゼ / 光学異性体 / リソソーム病 / シャペロン / リンパ吸収 / エンドサイトーシス / 脂溶性薬物 / ユビデカレノン / lymphatic absorption … More / endocytosis / lipophilic drug / Ubidecarenone / リソソーム蓄積症 / グルコセレブロシド / 水溶性アルカロイド / 糖鎖生合成 / LYSOSOME DISEASE / GLUCOCEREBROSIDE / SUGAR-MIMIC ALKALOIDS / ラムノシダーゼ / 結核菌 / グリコシダーゼ阻害剤 … More Except Principal Investigator リソソーム病 / グリコシダーゼ / イミノ糖 / シャペロン / フォールディング / テイーサックス病 / テイ-サックス病 / リポゾーム / リポソーム / Liposome / 線溶酵素 / ウロキナーゼ / 牛乳脂肪球被膜物質 / MFGM / エマルション / 消化管吸収 / 製剤素材 / リンパ移行 / DDS素材 / デオキシアザシュガー / キラル素子 / グリコシダーゼ阻害作用 / 閉環メタセシス / Garnerアルデヒド / 多元素環状化合物 / 海洋産アルカロイド / バツェラサイド / 環状カーバメート / クロスメタセシス / Batzellaside / 相対配置 / 絶対配置 / 立体化学 / 海綿 / 不斉アリル化 / ジアステレオマー / 超音波 / 周波数依存性 / キャビテーション / 経皮吸収 / 血栓溶解 / 超音波造影剤 / 遺伝子導入 / フリーラジカル / アポトーシス / 経度吸収 / ultrasound / Frequency dependent / caritation / Transdermal absorption / Thrombolysis / Echo contrast agent / 界面活性剤 / 混合ミセル / 粒径 / 転移領域 / 時間因子 / アンバライトXAD-2 / 準弾性光散乱 / 流体力学的半径 / フリーズフラクチャー / 粒子径 / Detergent / Mixed Micelle / Diameter / Transient State / Time Factor / 熱測定 / マイクロカロリメーター / フロー・スルー・セル / フィブリノーゲン / プラスミノーゲン / プラスミン / フィブリン / 活性定量 / 熱 / 活性 / 微少熱量計 / Calorimetry / Fibrinolytic activity / Microcalorimeter / Flow-throgh-Cell / Urokinase / Fibrinogen / Plasminogen / 温度感受性リポソーム / 線溶活性 / 温度感受性 / 血栓 / 新剤型 / 局所加温 / REV / 温度感受性リポゾーム / 相転移温度 / 人工血栓 / 界面活性剤除去法 / Thermo-Sensitive Liposome / Fibrinolytic Activity / Thermo-Sensitivity / Thrombosis Less

Analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease
- Principal Investigator
  
  KATO Atsushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
Strategy for designing selective rhamnosidase inhibitors: Synthesis and biological evaluation of L-DMDP cyclic isothioureasPrincipal Investigator
- Principal Investigator
  
  ADACHI ISAO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
Design and synthesis of iminosugar-based pharmacological chaperone as a structure stabilizing agent for mutation enzyme
- Principal Investigator
  
  Kato Atsushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
Design, synthesis, and biological evaluation of iminosugars as pharmacological chaperone for Gaucher disease
- Principal Investigator
  
  KATO Atsushi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
Inhibition activities of iminosugars against glycoprotein processingPrincipal Investigator
- Principal Investigator
  
  ADACHI Isao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Toyama
Synthetic Studies on Marine Alkaloid of Batzellasides Directed toward Novel Antidiabetic Drug
- Principal Investigator
  
  TOYOOKA Naoki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  University of Toyama
EFFECTS OF GLYCOSIDASE INHIBITORY SUGAR-MIMIC ALKALOIDS AGAINST LYSOSOME DISEASE.Principal Investigator
- Principal Investigator
  
  ADACHI Isao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
デオキシアザシュガー類の新規合成法の開発と生物活性評価
- Principal Investigator
  
  TAKAHATA Hiroki
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku Pharmaceutical University
Development and evaluation of ultrasound therapeutic system for drug activation
- Principal Investigator
  
  KONDO Takashi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
Biochemical Study for Absorption Mechanism of Lipophilic Drug from Intestine to Lymphatic fluidPrincipal Investigator
- Principal Investigator
  
  ADACHI Isao
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
牛乳脂肪球被膜物質のDDS素材としての可能性に関する研究
- Principal Investigator
  
  UENO Masaharu
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Toyama Medical and Pharmaceutical University
New Dosage Form for Treating a Thrombosis Using a Thermo-Sensitive Liposome
- Principal Investigator
  
  HORIKOSHI Isamu
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Toyama Medical and Pharmaceutical University
Studies on the Factors Dominating Liposome Size, Size Distribution and Permeability
- Principal Investigator
  
  UENO Masaharu
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Toyama Medical & Pharmaceutical University
New Mechod on Evaluating Fibrinolytic Activity using Calormitry
- Principal Investigator
  
  UENO Masaharu
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Toyama Medical & Pharmaceutical Univerisity

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Design of a new α-1-C-alkyl-DAB derivative acting as a pharmacological chaperone for β-glucocerebrosidase using ligand docking and molecular dynamics simulation.2018
- Author(s)
  Nakagom, I., Kato, A., Yamaotsu, N., Yoshida, T., Ozawa, S., Adachi, I., Hirono, S.
- Journal Title
  
  Molecules
  
  Volume: 23 Pages: 2683-2693
- DOI
  10.3390/molecules23102683
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Selective trihydroxylated azepane inhibitors of NagZ, a glycosidase involved in Pseudomonas aeruginosa resistance to β-lactam antibiotics2017
- Author(s)
  Bouquet, J., King, D. T., Vadlamani, G., Benzie, G. R., Iorga, B., Ide, D., Adachi, I., Kato, A., Vocadlo, D. J., Mark, B. L., Bleriot Y., Desire, J.
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 15 Pages: 4609-4619
- DOI
  10.1039/c7ob00838d
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] In silico analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease2017
- Author(s)
  Kato, A., Nakagome, I., Nakagawa, S., Kinami, K., Adachi, I., Jenkinson, S. F., Desire, J., Bleriot, Y., Nash, R. J., Fleet, G. W. J., Hirono, S.
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 15 Pages: 9297-9304
- DOI
  10.1039/c7ob02281f
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362, KAKENHI-PROJECT-15K07899
[Journal Article] Multivalency To Inhibit and Discriminate Hexosaminidases2017
- Author(s)
  Alvarez-Dorta D., King D. T., Legigan T., Ide D., Adachi I., Deniaud D., Desire J., Kato A., Vocadlo D., Gouin S. G., Bleriot Y.
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 23 Pages: 9022-9025
- DOI
  10.1002/chem.201701756
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Strategy for designing selective α-L-rhamnosidase inhibitors: Synthesis and biological evaluation of L-DMDP cyclic isothioureas.2017
- Author(s)
  Miyawaki, S., Hirokami, Y., Kinami, K., Hoshino, M., Minehira, D., Miyamoto, D., Nash, R. J., Fleet, G. W. J., Adachi, I., Kato, A.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 25 (1) Pages: 107-115
- DOI
  10.1016/j.bmc.2016.10.015
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143, KAKENHI-PROJECT-15K08021
[Journal Article] Docking study and biological evaluation of pyrrolidine-based iminosugars as pharmacological chaperones for Gaucher disease.2016
- Author(s)
  Atsushi Kato, Izumi Nakagome, Kasumi Sato, Arisa Yamamoto, Isao Adachi, Robert J. Nash, George W. J. Fleet, Yoshihiro Natori, Yasuka Wasuka, Tatsushi Imahori, Yuichi Yoshimura, Hiroki Takahata and Shuichi Hirono
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 14 Pages: 1039-1048
- DOI
  10.1039/c5ob02223a
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05437, KAKENHI-PROJECT-26460143, KAKENHI-PROJECT-25860088
[Journal Article] 3-Fluoro-azetidine carboxylic acids and trans,trans-3,4-difluoroproline as peptide scaffolds: inhibition of pancreatic cancer cell growth by a fluoroazetidine iminosugar.2015
- Author(s)
  Liu, Z., Jenkinson, S. F., Vermaas, T., Adachi, I., Wormald, M. R., Hata, U., Kurashima, Y., Kaji, A., Yu, C,-Y., Kato, A., Fleet, G. W. J.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 80(9) Pages: 4244-4258
- DOI
  10.1021/acs.joc.5b00463
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Design and synthesis of labystegines, hybrid iminosugars from LAB and calystegine, as inhibitors of intestinal α-glucosidases: binding conformation and interaction for ntSI.2015
- Author(s)
  Kato, A., Zhang, Z.-L., Wang, H.-Y., Jia, Y.-M., Yu, C.-Y., Kinami, K., Hirokami, Y., Tsuji, Y., Adachi, I., Nash, R. J., Fleet, G. W. J., Koseki, J., Nakagome, I., Hirono, S.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 80(9) Pages: 4501-4515
- DOI
  10.1021/acs.joc.5b00342
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Fluorinated and conformationally fixed derivatives of L-homoDMDP: synthesis and glycosidase inhibition.2015
- Author(s)
  Li, Yi.-X., Shimada, Y., Adachi, I., Kato, A., Jia, Y.-M., Fleet, G. W. J., Xiao, M., Yu. C.-Y.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 80(10) Pages: 5151-5158
- DOI
  10.1021/acs.joc.5b00571
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Docking and SAR studies of calystegines : binding orientation and influence on pharmacological chaperone effects for Gaucher's disease2014
- Author(s)
  Kato, A., Nakagome, I., Nakagawa, S., Koike, Y., Nash, R. J., Adachi, I., Hirono, S.
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 22 (8) Pages: 2435-2441
- DOI
  10.1016/j.bmc.2014.02.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Synthesis of 1,2-trans-2-acetamido-2-deoxyhomoiminosugars.2014
- Author(s)
  Bleriot, Y., Tran, A. T., Prencipe, G., Jagadeesh, Y., Auberger, N., Zhu, S., Gauthier, C., Zhang, Y., Desire;, J., Adachi, I., Kato, A., Sollogoub, M.
- Journal Title
  
  Org. Lett.
  
  Volume: 16 (21) Pages: 5516-5519
- DOI
  10.1021/ol502929h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors.2014
- Author(s)
  Kato, A., Hirokami, Y., Kinami, K., Tsuji, Y., Miyawaki, S., Adachi, I., Hollinshead, J., Nash, R. J. Kiappes, J. L., Zitzmann, N., Cha, J. K., Molyneux, R. J., Fleet, G. W. J., Asano, N.
- Journal Title
  
  Phytochemistry
  
  Volume: 111 Pages: 124-131
- DOI
  10.1016/j.phytochem.2014.12.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Synthesis of eight stereoisomers of pochonicine : Nanomolar inhibition ofβ-N-acetylhexosaminidases2013
- Author(s)
  Zhu, J. -S., Nakagawa, S., Chen, W., Adachi, I., Jia, Y. -M., Hu, X. -G., Fleet, G. W. J., Wilson, F. X., Nitoda, T., Horne, G., van Well, R., Kato, A., Yu, C. -Y.
- Journal Title
  
  J. Org. Chem
  
  Volume: 78 (20) Pages: 10298-10309
- DOI
  10.1021/jo401694e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] General synthesis of sugar-derived azepane nitrones : precursors of azepane iminosugars2013
- Author(s)
  Zhao, W. -B., Nakagawa, S., Kato, A., Adachi, I., Jia, Y. -M., Hu, X. -G., Fleet, G. W. J., Wilson, F. X., Horne, G., Yoshihara, A., Izumori, K., Yu, C. -Y.
- Journal Title
  
  J. Org. Chem
  
  Volume: 78 (7) Pages: 3208-3221
- DOI
  10.1021/jo400130p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] α-1-C-Butyl-1,4-dideoxy-1,4-imino-L-arabinitol as a Second-Generation Iminosugar-Based Oral α-Glucosidase Inhibitor for Improving Postprandial Hyperglycemia2012
- Author(s)
  Kato, A., Hayashi, E., Miyauchi, S., Adachi, I., Imahori, T., Natori, Y., Yoshimura, Y., Nash, R. J., Shimaoka, H., Nakagome, I., Koseki, J., Hirono, S., Takahata, H.
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 55 (23) Pages: 10347-10362
- DOI
  10.1021/jm301304e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059, KAKENHI-PROJECT-22590104, KAKENHI-PROJECT-23590012, KAKENHI-PROJECT-23590127, KAKENHI-PROJECT-23790138
[Journal Article] Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymet hylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol2012
- Author(s)
  Araujo, N., Jenkinson, S. F., Martinez, R. F., Glawar, A. F. G., Wormald, M. R., Butters, T. D., Nakagawa, S., Adachi, I., Kato, A. Yoshihara, A., Akimitsu, K., Izumori, K., Fleet, G. W. J.
- Journal Title
  
  Org. Lett
  
  Volume: 14 (16) Pages: 4174-4177
- DOI
  10.1021/ol301844n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059, KAKENHI-PROJECT-23590127
[Journal Article] α-1-C-Butyl-LAB as a second-generation iminosugar-based oral α-glucosidase inhibitor for improving postprandial hyperglycemia2012
- Author(s)
  Kato, A., Hayashi, E., Miyauchi, S., Adachi, I., Imahori, T., Natori, Y., Yoshimura, Y., Nash, R. J., Shimaoka, H., Nakagome, I., Koseki, J., Hirono, S., Takahata, H
- Journal Title
  
  J. Med. Chem
  
  Volume: 55(23) Pages: 10347-10362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Eight stereoisomers of homonojirimycin from D-mannose2012
- Author(s)
  Lenagh-Snow, G. M. J., Jenkinson, S. F., Newberry, S. J., Kato, A., Nakagawa, S., Adachi, I., Wormald, M. R., Yoshihara, A., Morimoto, K., Akimitsu, K., Izumori, K., Fleet, G. W. J.
- Journal Title
  
  Org. Lett
  
  Volume: 14 (8) Pages: 2050-2053
- DOI
  10.1021/ol3005744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Synthesis of 1-Alkyl-2-deoxyiminofuranoses via The Iridium- catalyzed Intramolecular Cyclization of an Allylic Carbonate2012
- Author(s)
  Natori, Y., Kikuchi, S., Yoshimura, Y., Kato, A., Adachi, I., Takahata, H.
- Journal Title
  
  Heterocycles, 2012, 86, 1401-1417.
  
  Volume: 86 (2) Pages: 1401-1417
- DOI
  10.3987/com-12-s(n)99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059, KAKENHI-PROJECT-22590104, KAKENHI-PROJECT-23790138
[Journal Article] Asymmetric synthesis of 2-propylisofagomine using allylic hydroxy group accelerated ring-closing enyne metathesis.2012
- Author(s)
  Taguchi, T., Imahori, T., Yoshimura, Y., Kato, A., Adachi, I., Kawahara, M., Yamaguchi, K., Takahata, H.
- Journal Title
  
  Heterocycles
  
  Volume: 84 (2) Pages: 929-944
- DOI
  10.3987/com-11-s(p)74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Glycosidase inhibition by all 10 stereoisomeric 2,5-dideoxy-2,5-iminohexitols prepared from the enantiomers of glucuronolactone2012
- Author(s)
  Ayers, B., Ngo, M., Jenkinson, S. F Martínez, R. F., Shimada, Y., Adachi, I., Weymouth-Wilson, A. C., Kato, A., Fleet, G. W. J.
- Journal Title
  
  J. Org. Chem
  
  Volume: 77 (18) Pages: 7777-7792
- DOI
  10.1021/jo301243s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Asymmetric synthesis of 1-alkyl-2-deoxyiminofuranoses via The iridium-catalyzed intramolecular cyclization of an allylic carbonate2012
- Author(s)
  Natori, Y., Kikuchi, S., Yoshimura, Y., Kato, A., Adachi, I., Takahata, H
- Journal Title
  
  Heterocycles
  
  Volume: 86(2) Pages: 1401-1417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Asymmetric synthesis of 2-propylisofagomine using allylic hydroxy group accelerated ring-closing enyne metathesis2012
- Author(s)
  Taguchi, T., Imahori, T., Yoshimura, Y., Kato, A., Adachi, I., Kawahara, M., Yamaguchi, K., Takahata, H
- Journal Title
  
  Heterocycles
  
  Volume: 84(2) Pages: 929-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol2012
- Author(s)
  Araujo, N., Jenkinson, S. F., Martinez, R. F., Glawar, A. F. G., Wormald, M. R., Butters, T. D., Nakagawa, S., Adachi, I., Kato, A.Yoshihara, A., Akimitsu, K., Izumori, K., Fleet, G. W. J
- Journal Title
  
  Org. Lett
  
  Volume: 14(16) Pages: 4174-4177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Looking-glass synergistic pharmacological chaperones: DGJ and L-DGJ from the enantiomers of tagatose2011
- Author(s)
  Jenkinson, S. F., Fleet, G. W. J., Nash, R. J., Koike, Y., Adachi, I., Yoshihara, A., Morimoto, K., Izumori, K., Kato, A
- Journal Title
  
  Org. Lett
  
  Volume: 13(15) Pages: 4064-4067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Looking-glass synergistic pharmacological chaperones: DGJ and L-DGJ from the enantiomers of tagatose.2011
- Author(s)
  Jenkinson, S. F., Fleet, G. W. J., Nash, R. J., Koike, Y., Adachi, I., Yoshihara, A., Morimoto, K., Izumori, K., Kato, A
- Journal Title
  
  Org. Lett.
  
  Volume: 13 (15) Pages: 4064-4067
- DOI
  10.1021/ol201552q
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Synthesis, conformational analysis, and evaluation as glycosidase inhibitors of two ether-bridged iminosugars2011
- Author(s)
  Luo, B., Marcelo, F., Desire, J., Zhang, Y., Sollogoub, M., Kato, A., Adachi, I., Canada, F. Jimenez-Barbero, J., Bleriot, Y
- Journal Title
  
  J. Carb. Chem
  
  Volume: 30(7-9) Pages: 641-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] ヒメコウゾ (Broussonetia kazinoki)に含まれるbroussonetine MおよびWのグリコシダーゼ阻害活性と誘導体化の試み2019
- Author(s)
  島立優奈、加藤　敦、木南今日子、足立伊佐雄
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08362
[Presentation] Hex A高親和性リガンドのin silico解析とTay-Sachs病に対するファーマコロジカルシャペロン効果の検証2019
- Author(s)
  加藤　敦、中込泉、中川進平、島立優奈、足立伊佐雄、広野修一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08362
[Presentation] 新規ピロリジン型イミノ糖誘導体のデザインとゴーシェ病に対するシャペロン効果について2019
- Author(s)
  島立優奈、加藤　敦、久保萌美、井出大介、足立伊佐雄
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08362
[Presentation] Hex A高親和性リガンドの創製とTay-Sachs病に対するファーマコロジカルシャペロン効果の検証2018
- Author(s)
  加藤　敦、中込　泉、久保萌美、今枝秀貴、足立伊佐雄、広野修一
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K08362
[Presentation] 選択的α-L-rhamnosidase阻害剤のデザイン戦略：L-DMDP cyclic isothioureasの合成と構造最適化2017
- Author(s)
  星野雅子、加藤敦、宮脇章太、広上由季、木南今日子、友原啓介、宮本大樹、足立伊佐雄、豊岡尚樹
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター他
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08021
[Presentation] コンピュータリガンドドッキングと分子動力学シミュレーションによるHexosaminidase A―リガンド複合体の相互作用解析2017
- Author(s)
  中込泉、加藤敦、山乙教之、足立伊左雄、広野修一
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター他
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] ピロリジン型イミノ糖を基盤とした新規GCase高親和性リガンドのデザインとファーマコロジカルシャペロン効果について2016
- Author(s)
  加藤敦、山本亜里紗、友原啓介、足立伊佐雄、渡邊靖香、名取良浩、吉村祐一、中込　泉、広野修一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Hexosaminidase Aの高親和性リガンドに対するイン・シリコ相互作用解析2016
- Author(s)
  中込　泉、加藤　敦、山乙　教之、足立伊佐雄、広野修一
- Organizer
  第44回構造活性相関シンポジウム
- Place of Presentation
  京都大学医学部創立百年記念施設
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] イミノ糖を基盤としたGCase高親和性リガンドの創製とファーマコロジカルシャペロン効果について2016
- Author(s)
  加藤敦、中込　泉、佐藤香純、山本亜里紗、足立伊佐雄、広野修一
- Organizer
  第35回糖質学会年会
- Place of Presentation
  高知市文化プラザ　かるぽーと
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Computational study of the interaction of α-1-C-alkyl derivatives of 1,4-dideoxy-1,4-imino-D-arabinitol with β-glucocerebrosidase2015
- Author(s)
  中込　泉、加藤　敦、山乙教之、吉田智喜、足立伊佐雄、広野修一
- Organizer
  第43回構造活性相関シンポジウム
- Place of Presentation
  新潟日報メディアシップ　日報ホール
- Year and Date
  2015-09-27
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Catalytic asymmetric syntheses and biological evaluations of α-1-C-substituted L-iminofuranose derivatives as α-glucosidase inhibitor2015
- Author(s)
  Natori, Y., Kato, A., Adachi, I., Yoshimura, Y.
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Catalytic asymmetric syntheses and biological evaluations of α-1-C-substituted L-iminofuranose derivatives as α-glucosidase inhibitor2015
- Author(s)
  Natori, Y., Kato, A., Adachi, I., Yoshimura, Y.
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08021
[Presentation] In silico study on the interaction of high affinity ligand calystegine B2 with β-glucocerebrosidase2015
- Author(s)
  Nakagome, I., Kato, A., Yoshida, T., Yamaotsu, N., Adachi, I., Hirono, S.
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成と酵素阻害活性評価2015
- Author(s)
  佐久間俊嘉、名取良浩、中川進平、加藤　敦、足立伊佐雄、吉村祐一
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-15K08021
[Presentation] Synthesis and interactions of rhamnose iminosugar mimics with the rhamnose operon, rhamnosidases, and rhamnose isomerase2015
- Author(s)
  Liu, Z., Kelly, C., Yoshihara, A., Izumori, K., Wormald, M., Otero-Casas, J., Estevez-Reino, A., Heap, J., Kato, A., Adachi, I., Jenkinson, S., Fleet, G., Estevez, R.
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08021
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成と酵素阻害活性評価2015
- Author(s)
  佐久間俊嘉、名取良浩、中川進平、加藤　敦、足立伊佐雄、吉村祐一
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Calystegine類のβ-glucocerebrosidaseに対する結合親和性とファーマコロジカルシャペロン効果について2014
- Author(s)
  加藤敦、中込泉、中川進平、広野修一、足立伊佐雄
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] トリアゾール環を側鎖に持つD-イミノフラノース誘導体の合成と生物活性評価2014
- Author(s)
  名取良浩、盛　友莉恵、吉村祐一、佐藤香純、加藤　敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] β-1-C-n-ブチル-L-イミノ糖誘導体の触媒的不斉合成とα-グルコシダーゼ阻害作用に対する構造活性相関2014
- Author(s)
  佐久間俊嘉、名取良浩、吉村祐一、加藤敦、足立伊佐雄、中川進平、高畑廣紀
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] DGJNAc誘導体の結合親和性とpharmacological chaperone活性について2014
- Author(s)
  中川進平、加藤敦、足立伊佐雄
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Calystegine類のβ-glucocerebrosidaseに対する結合親和性とファーマコロジカルシャペロン効果について2014
- Author(s)
  加藤　敦、中込　泉、中川進平、広野修一、足立伊佐雄
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 新規β-glucocerebrosidase高親和性リガンドcalystegine B_2の結合様式に対するin silico解析2014
- Author(s)
  中込泉、加藤敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] β-1-C-n-ブチル-L-イミノ糖誘導体の触媒的不斉合成とα-グルコシダーゼ阻害作用に対する構造活性相関2014
- Author(s)
  佐久間俊嘉、名取良浩、吉村祐一、加藤　敦、足立伊佐雄、中川進平、高畑廣紀
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 新規β-glucocerebrosidase高親和性リガンドcalystegine B2の結合様式に対するin silico解析2014
- Author(s)
  中込　泉、加藤　敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] トリアゾール環を側鎖に持つD-イミノフラノース誘導体の合成と生物活性評価2014
- Author(s)
  名取良浩、盛友莉恵、吉村祐一、佐藤香純、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] DGJNAc誘導体の結合親和性とpharmacological chaperone活性について2014
- Author(s)
  中川進平、加藤　敦、足立伊佐雄
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] コンピュータリガンドドッキングによるα-glucosidase阻害剤α-1-C-Butyl-LABのmaltase及びβ-glucosidaseに対する結合様式解析2013
- Author(s)
  中込泉、小関準、山乙教之、合田浩明、広野修一、加藤敦、林恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 新規β-glucocerebrosidase阻害剤calystegine B_2のインシリコ結合様式解析2013
- Author(s)
  中込泉、加藤敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  第41回構造活性相関シンポジウム
- Place of Presentation
  西宮
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 七員環型イミノ糖の誘導体化とグリコシダーゼ阻害活性2013
- Author(s)
  岩城蓮、加藤敦、中川進平、足立伊佐雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について(第2報)2013
- Author(s)
  加藤敦、林恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、島岡秀行、中込泉、小関準、広野修一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について（第2報）2013
- Author(s)
  加藤　敦、林　恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、島岡秀行、中込　泉、小関　準、広野修一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] α-1-C-アルキル-D-アラビノイミノ糖誘導体の触媒的不斉合成とその生物活性2013
- Author(s)
  渡邊靖香、佐久間俊嘉、名取良浩、吉村祐一、佐藤香純、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成2013
- Author(s)
  佐久間俊嘉、渡邊はるか、名取良浩、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] α-1-C-アルキル-D-アラビノイミノ糖誘導体の触媒的不斉合成とその生物活性2013
- Author(s)
  渡邊靖香、佐久間俊嘉、名取良浩、吉村祐一、佐藤香純、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成2013
- Author(s)
  佐久間俊嘉、渡邊はるか、名取良浩、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について(第1報)2013
- Author(s)
  足立伊佐雄、加藤敦、林恵利奈、中川進平、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について(第1報)2013
- Author(s)
  足立伊佐雄、加藤敦、林恵利奈、中川進平、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] 新規β-glucocerebrosidase阻害剤calystegine B2のインシリコ結合様式解析2013
- Author(s)
  中込　泉、加藤　敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  第41回構造活性相関シンポジウム
- Place of Presentation
  関西学院会館
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] ピロリジン型イミノ糖の構造活性相関に基づいたシャペロン様化合物のデザイン研究2013
- Author(s)
  中川進平、加藤敦、足立伊佐雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について（第1報）2013
- Author(s)
  足立伊佐雄、加藤　敦、林　恵利奈、中川進平、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1位に4-アリールブチル基を導入したL-アラビノイミノ糖誘導体の不斉合成と生物活性評価2013
- Author(s)
  名取良浩、今堀龍志、吉村祐一、嶋田陽介、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について(第2報)2013
- Author(s)
  加藤敦、林恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、島岡秀行、中込泉、小関準、広野修一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] α-1-C-アルキル-D-アラビノイミノ糖誘導体の触媒的不斉合成とその生物活性2013
- Author(s)
  渡邊靖香、佐久間俊嘉、名取良浩、吉村祐一、佐藤香純、加藤　敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1位に4-アリールブチル基を導入したL-アラビノイミノ糖誘導体の不斉合成と生物活性評価2013
- Author(s)
  名取良浩、今堀龍志、吉村祐一、嶋田陽介、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について（第2報）2013
- Author(s)
  加藤　敦、林　恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、島岡秀行、中込　泉、小関　準、広野修一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について（第1報）2013
- Author(s)
  足立伊佐雄、加藤　敦、林　恵利奈、中川進平、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] C1位に4-アリールブチル基を導入したL-アラビノイミノ糖誘導体の触媒的不斉合成2012
- Author(s)
  名取良浩、今堀龍志、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1位に4-アリールブチル基を組み込んだL-アラビノイミノフラノースの触媒的不斉合成と生物活性評価2012
- Author(s)
  名取良浩、吉村祐一、高畑廣紀、嶋田陽介、加藤敦、足立伊佐雄
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] Docking and SAR studies of D- and L-isofagomine isomers as humanβ-glucocerebrosidase inhibitors2012
- Author(s)
  Kato, A., Miyauchi, S., Nakagome, I., Yoshimura, Y., Hirono, S., Takahata, H., Adachi, I
- Organizer
  8th AFMC International Medicinal Chemistry Symposium (AIMECS11)
- Place of Presentation
  Keio, Japan
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] C1位に4-アリールブチル基を組み込んだL-アラビノイミノフラノースの触媒的不斉合成と生物活性評価2012
- Author(s)
  名取良浩、吉村祐一、高畑廣紀、嶋田陽介、加藤敦、足立伊佐雄
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] L-アラビノイミノフラノースをベースとした食後過血糖改善薬のデザイン合成研究2012
- Author(s)
  加藤敦、林恵利奈、中川進平、足立伊佐雄、中込泉、小関準、広野修一、名取良浩、今堀龍志、吉村祐一、高畑廣紀
- Organizer
  第31回糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] N-アセチルヘキソサミニダーゼを標的とした1-N型イミノ糖のデザイン研究2012
- Author(s)
  嶋田陽介、加藤敦、佐藤香純、中川進平、足立伊佐雄
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Sucrase及びIsomaltaseへのLAB化合物の結合様式に関する理論的研究2012
- Author(s)
  小関準、中込泉、足立伊佐雄、加藤敦、広野修一
- Organizer
  第40回構造活性相関シンポジウム
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] LABNAcを中心としたβ-N-acetyl-hexosaminidaseに対する構造活性相関とPC活性について2012
- Author(s)
  中川進平、加藤敦、嶋田陽介、足立伊
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Isofagomine類のβ-glucocerebrosidaseに対する結合親和性と構造活性相関について2012
- Author(s)
  加藤敦、中川進平、足立伊佐雄、中込泉、広野修一、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] C1位アルキルL-アラビノイミノフラノース誘導体の触媒的不斉合成とその生物活性2011
- Author(s)
  名取良浩、今堀龍志、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] フコシダーゼ阻害活性が期待されるイミノ糖誘導体の合成研究2011
- Author(s)
  坂知樹、杉本健士、松谷裕二、中川進平、山下侑子、加藤敦、足立伊佐雄、豊岡尚樹
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1置換L-アラビノイミノ糖誘導体の触媒的不斉合成2011
- Author(s)
  名取良浩、今堀龍志、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1位アルキルL-アラビノイミノフラノース誘導体の触媒的不斉合成とその生物活性2011
- Author(s)
  名取良浩、今堀龍志、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Docking and SAR studies of D- and L-isofagomine isomers as human β-glucocerebrosidase inhibitors2011
- Author(s)
  Kato, A., Miyauchi, S., Nakagome, I., Yoshimura, Y., Hirono, S., Takahata, H., Adachi, I.
- Organizer
  8th AFMC International Medicinal Chemistry Symposium (AIMECS11)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] D-およびL-isofagomine類の合成とグリコシダーゼ阻害活性2011
- Author(s)
  加藤敦、宮内沙織、中川進平、足立伊佐雄、中込泉、広野修一、吉村祐一、高畑廣紀
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Pharmacological chaperone活性を有するL型イミノ糖の可能性について2010
- Author(s)
  小池有理子、加藤敦、足立伊佐雄、石井達
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] α-glucosidase 阻害剤 α-1-C-Butyl-LAB のイソマルターゼに対する結合様式解析
- Author(s)
  中込　泉、小関　準、加藤　敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] β-glucocerebrosidaseに対する高親和性リガンドcalystegine B2類縁体の計算化学的相互作用解析
- Author(s)
  中込　泉、加藤　敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  第42回構造活性相関シンポジウム
- Place of Presentation
  くまもと森都心プラザ
- Year and Date
  2014-11-13 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] GCase高親和性リガンドである1-N型イミノ糖の結合親和性とファーマコロジカルシャペロン効果について
- Author(s)
  加藤敦、山本亜里紗、中川進平、足立伊佐雄、中込泉、広野修一
- Organizer
  第33回糖質学会年会
- Place of Presentation
  名古屋大学豊田講堂
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-26460143

1. KATO Atsushi (60303236)

# of Collaborated Projects: 8 results

# of Collaborated Products: 92 results
2. UENO Masaharu (40080197)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TAKAHATA Hiroki (00109109)

# of Collaborated Projects: 3 results

# of Collaborated Products: 38 results
4. HIRONO Shuichi (30146328)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
5. ISHII Satoshi (00222935)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 名取良浩 (50584455)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. TOYOOKA Naoki (10217565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KONDO Takashi (40143937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TANABE Kiyoshi (30293301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ASANO Naoki (50121265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKAHASHI Kaoru (70135028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HORIKOSHI Isamu (70019123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 大内秀一 (30275606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 梅村晋一郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHIN-ICHIRO Umemura

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. IMAHORI Tatsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 吉村祐一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 中込泉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ADACHI Isao 足立 伊左雄

ADACH Isaso 足立 伊左雄

足立 伊左雄 アダチ イサオ

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Strategy for designing selective rhamnosidase inhibitors: Synthesis and biological evaluation of L-DMDP cyclic isothioureasPrincipal Investigator

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Inhibition activities of iminosugars against glycoprotein processingPrincipal Investigator

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EFFECTS OF GLYCOSIDASE INHIBITORY SUGAR-MIMIC ALKALOIDS AGAINST LYSOSOME DISEASE.Principal Investigator

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Biochemical Study for Absorption Mechanism of Lipophilic Drug from Intestine to Lymphatic fluidPrincipal Investigator

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ADACHI Isao 足立伊左雄

ADACH Isaso 足立伊左雄

足立伊左雄アダチイサオ