Kato Atsushi 加藤敦

… Alternative Names

加藤敦カトウアツシ

KATO Atsushi 加藤敦

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Researcher Number	60303236
Other IDs
Affiliation (Current)	2022: 富山大学, 学術研究部薬学・和漢系, 教授
Affiliation (based on the past Project Information) *help	2021: 富山大学, 学術研究部薬学・和漢系, 教授 2019: 富山大学, 学術研究部薬学・和漢系, 准教授 2019: 富山大学, 学術研究部薬学・和漢系, 教授 2016 – 2018: 富山大学, 附属病院, 准教授 2015: 富山大学, 付属病院薬剤部, 准教授 … More 2008 – 2015: University of Toyama, 大学病院, 准教授 2014: 富山大学, 附属病院, 准教授 2012: 富山大学, 付属病院薬剤部, 准教授 2007 – 2008: University of Toyama, 附属病院, 准教授 2006: 富山大学, 附属病院, 助教授 2005: 富山医薬大, 医学部附属病院, 助手 2002 – 2004: 富山医科薬科大学, 附属病院, 助手 2001: 富山医科薬科大学, 付属病院, 助手 Less
Review Section/Research Field	Principal Investigator Drug development chemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related Except Principal Investigator Drug development chemistry / Science and Engineering / Chemical pharmacy / Biological pharmacy / Biological pharmacy
Keywords	Principal Investigator リソソーム病 / グリコシダーゼ / イミノ糖 / シャペロン / フォールディング / ケミカルシャペロン / 小胞体品質管理機構 / テイーサックス病 / テイ-サックス病 / 糖類似アルカロイド / ポンペ病 / シャペロン療法 / 酵素補充療法 … More Except Principal Investigator … More イミノ糖 / グリコシダーゼ / 医薬品化学 / 医薬分子設計 / 酵素阻害活性物質 / ラムノシダーゼ / デオキシアザシュガー / キラル素子 / グリコシダーゼ阻害作用 / 閉環メタセシス / Garnerアルデヒド / 多元素環状化合物 / 海洋産アルカロイド / バツェラサイド / 環状カーバメート / クロスメタセシス / Batzellaside / 相対配置 / 絶対配置 / 立体化学 / 海綿 / 不斉アリル化 / ジアステレオマー / 光学異性体 / リソソーム病 / シャペロン / 創薬化学 / α-グルコシダーゼ阻害作用 / 糖尿病治療薬 / 触媒的不斉合成 / fucosidase / rhamnosidase / inhibitors / エナンチオダイバージェントストラテジー / ポリヒドロキシピロリチジン / フコシダーゼ / フコシダーゼ阻害剤 / 擬態 / 新規アミド型化合物 / リソソーム蓄積症 / グルコセレブロシド / 水溶性アルカロイド / 糖鎖生合成 / LYSOSOME DISEASE / GLUCOCEREBROSIDE / SUGAR-MIMIC ALKALOIDS / 結核菌 / グリコシダーゼ阻害剤 / α-グルコシダーゼ阻害薬 / ゴーシェ病治療薬 / ケミカルシャペロン療法 / イミノ糖誘導体 / ライソゾーム病 / 化学シャペロン療法 / 構造活性相関研究 Less

変異酵素の構造安定化に基づく機能性シャペロン化合物の創製とポンペ病治療への応用Principal Investigator
- Principal Investigator
  
  加藤敦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  University of Toyama
Analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs diseasePrincipal Investigator
- Principal Investigator
  
  KATO Atsushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
Strategy for designing selective rhamnosidase inhibitors: Synthesis and biological evaluation of L-DMDP cyclic isothioureas
- Principal Investigator
  
  ADACHI ISAO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
Design and synthesis of iminosugar-based pharmacological chaperone as a structure stabilizing agent for mutation enzymePrincipal Investigator
- Principal Investigator
  
  Kato Atsushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
Asymmetric syntheses of various iminofuranoses having a side chain at C1 position and their biological evaluation as enzyme inhibitors
- Principal Investigator
  
  NATORI Yoshihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tohoku Pharmaceutical University
Synthetic Studies on novel fucosidase and rhamnosidase inhibitors
- Principal Investigator
  
  TOYOOKA naoki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
Design, synthesis, and biological evaluation of iminosugars as pharmacological chaperone for Gaucher diseasePrincipal Investigator
- Principal Investigator
  
  KATO Atsushi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
Catalytic enantioselective synthesis and biological evaluation of 1-C-alkyl-L-arabinoiminofuranose
- Principal Investigator
  
  NATORI Yoshihiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tohoku Pharmaceutical University
Inhibition activities of iminosugars against glycoprotein processing
- Principal Investigator
  
  ADACHI Isao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Toyama
Synthetic Studies on Marine Alkaloid of Batzellasides Directed toward Novel Antidiabetic Drug
- Principal Investigator
  
  TOYOOKA Naoki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  University of Toyama
Development of new concept drugs against lysosome disease base on enzyme structures stabilized effectsPrincipal Investigator
- Principal Investigator
  
  KATO Atsushi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  University of Toyama
変異タンパク質の分子生物学的特性に基づいたリソソーム病治療薬の開発Principal Investigator
- Principal Investigator
  
  加藤敦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Toyama Medical and Pharmaceutical University
EFFECTS OF GLYCOSIDASE INHIBITORY SUGAR-MIMIC ALKALOIDS AGAINST LYSOSOME DISEASE.
- Principal Investigator
  
  ADACHI Isao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
デオキシアザシュガー類の新規合成法の開発と生物活性評価
- Principal Investigator
  
  TAKAHATA Hiroki
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku Pharmaceutical University

[Journal Article] 5-C-Branched deoxynojirimycin: Strategy for designing a DNJ-based pharmacological chaperone with nanomolar affinity for Pompe disease.2022
- Author(s)
  Kato Atsushi、Nakagome Izumi、Kanekiyo Uta、Lu Tian-Tian、Li Yi-Xian、Yoshimura Kosuke、Kishida Mana、Shinzawa Kenta、Yoshida Tomoki、Tanaka Nobutada、Jia Yue-Mei、Nash Robert J.、Fleet George W. J.、Yu Chu-Yi
- Journal Title
  
  J. Med. Chem.
  
  Volume: 65 Pages: 2329-2341
- DOI
  10.1021/acs.jmedchem.1c01673
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02876, KAKENHI-PROJECT-21K06451
[Journal Article] Synthesis and glycosidase inhibition of 5-C-alkyl-DNJ and 5-C-alkyl-L-ido-DNJ derivatives.2021
- Author(s)
  Lu, T.-T., Shimadate, Y., Cheng, B., Kanekiyo, U., Kato, A, Wang, J.-Z., Li, Y.-X., Jia, Y.-M., Fleet, G.W.J., Yu, C.-Y.
- Journal Title
  
  Eur. J. Med. Chem.
  
  Volume: 224 Pages: 113716-113716
- DOI
  10.1016/j.ejmech.2021.113716
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06451
[Journal Article] Stereocomplementary synthesis of casuarine and its 6-epi-, 7-epi-, and 6,7-diepi-stereoisomers.2021
- Author(s)
  Li, Y.-X., Wang, J.-Z., Kato, A., Shimadate, Y., Kise, M., Jia, Y.-M., Fleet, G.W.J., Yu, C.-Y.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 19 (43) Pages: 9410-9420
- DOI
  10.1039/d1ob01725j
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06451
[Journal Article] Synthesis and glycosidase inhibition of broussonetine M and its analogues.2019
- Author(s)
  Wu, Q.-K., Kinami, K., Kato, A., Li, Y.-X., Jia, Y.-M., Fleet, G. W. J., Yu, C.-Y.
- Journal Title
  
  Molecules
  
  Volume: 24 (20) Pages: 3712-3712
- DOI
  10.3390/molecules24203712
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of β-glucocerebrosidase inhibition.2019
- Author(s)
  Martinez-Bailen, M., Carmona, A. T., Patterson-Orazem, A. C., Lieberman, R. L., Ide, D., Kubo, M., Kato, A., Robina, I., Moreno-Vargas. A. J.
- Journal Title
  
  Bioorg. Chem.
  
  Volume: 86 Pages: 652-664
- DOI
  10.1016/j.bioorg.2019.02.025
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Corrected structure of natural hyacinthacine C1 via total synthesis.2019
- Author(s)
  Carroll, A. W., Willis, A. C., Hoshino, M., Kato, A., Pyne, S. G.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 82 (2) Pages: 358-367
- DOI
  10.1021/acs.jnatprod.8b00879
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Synthesis and glycosidase inhibition of conformationally locked DNJ and DMJ derivatives exploiting a 2-oxo-C-allyl iminosugar.2019
- Author(s)
  20)Foucart, Q., Shimadate, Y., Marrot, J., Kato, A., Desire, J., Bleriot, Y.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 17 (30) Pages: 7204-7214
- DOI
  10.1039/c9ob01402k
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Isolation from Stevia rebaudiana of DMDP acetic acid, a new class of iminosugar amino acid: synthesis and glycosidase inhibition profile of glycine and β-alanine pyrrolidine amino acids.2019
- Author(s)
  Martinez, R. F., Jenkinson, S. F., Nakagawa, S., Kato, A., Wormald, M. R., Fleet, G. W. J., Hollinshead, J., Nash, R. J.
- Journal Title
  
  Amino Acids
  
  Volume: 51 (7) Pages: 991-998
- DOI
  10.1007/s00726-019-02730-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Chain-branched polyhydroxylated octahydro-1H-indoles, as potential leads against lysosomal storage diseases.2019
- Author(s)
  Estevez, J. C., Gonzalez, M. A., Villaverde, M. C., Hirokami, Y., Kato, A., Sussman, F., Reza, D., Estevez, R. J.
- Journal Title
  
  Pharmaceuticals
  
  Volume: 12 (2) Pages: 47-47
- DOI
  10.3390/ph12020047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Characterising the selectivity of ER α-glucosidase inhibitors.2019
- Author(s)
  O’Keefe, S., Roebuck, Q., Nakagome, I., Hirono, S., Kato, A., Nash, R. J., High, S.
- Journal Title
  
  Glycobiology
  
  Volume: 29 (7) Pages: 530-542
- DOI
  10.1093/glycob/cwz029
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Discovery of a potent α-galactosidase inhibitor by in situ analysis of a library of pyrrolizidine-(thio)urea hybrid molecules generated via click chemistry.2018
- Author(s)
  Eias-Rodriguez, P., Pingitore, V., Carmona, A., Moreno-Vargas, A., Ide, D., Miyawaki, S., Kato, A., Alvarez, E., Robina, I.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 83 Pages: 8863-8873
- DOI
  10.1021/acs.joc.8b01073
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Design of a new α-1-C-alkyl-DAB derivative acting as a pharmacological chaperone for β-glucocerebrosidase using ligand docking and molecular dynamics simulation.2018
- Author(s)
  Nakagom, I., Kato, A., Yamaotsu, N., Yoshida, T., Ozawa, S., Adachi, I., Hirono, S.
- Journal Title
  
  Molecules
  
  Volume: 23 Pages: 2683-2693
- DOI
  10.3390/molecules23102683
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] 2-Acetamido-2-deoxy-L-iminosugar C-alkyl and C-aryl glycosides: synthesis and glycosidase inhibition.2018
- Author(s)
  Fontelle, N., Yamamoto, Arda, A., Jimenez-Barbero, J., Kato, A., Desire, J., Bleriot,
- Journal Title
  
  Eur. J. Org. Chem.
  
  Volume: 40 Pages: 5477-5488
- DOI
  10.1002/ejoc.201800678
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Design and synthesis of N-acetylglucosamine derived 5a-carbasugar analogues as glycosidase inhibitors.2018
- Author(s)
  Narayana, C., Kumari, P., Ide, D., Hoshino, M., Kato, A., Sagar, M.
- Journal Title
  
  Tetrahedron
  
  Volume: 74 Pages: 1957-1964
- DOI
  10.1016/j.tet.2018.02.063
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Divergent synthesis of new α-glucosidase inhibitors obtained through a vinyl Grignard-mediated carbocyclization.2018
- Author(s)
  Hedberg, C., Knudsen, I. M. B., Ladefoged, L. K., Ide, D., Brinko, A., Eikeland, E. Z., Kato, A., Jensen, H. H.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 16 Pages: 6250-6261
- DOI
  10.1039/c8ob01433g
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Selective trihydroxylated azepane inhibitors of NagZ, a glycosidase involved in Pseudomonas aeruginosa resistance to β-lactam antibiotics2017
- Author(s)
  Bouquet, J., King, D. T., Vadlamani, G., Benzie, G. R., Iorga, B., Ide, D., Adachi, I., Kato, A., Vocadlo, D. J., Mark, B. L., Bleriot Y., Desire, J.
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 15 Pages: 4609-4619
- DOI
  10.1039/c7ob00838d
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] In silico analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs disease2017
- Author(s)
  Kato, A., Nakagome, I., Nakagawa, S., Kinami, K., Adachi, I., Jenkinson, S. F., Desire, J., Bleriot, Y., Nash, R. J., Fleet, G. W. J., Hirono, S.
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 15 Pages: 9297-9304
- DOI
  10.1039/c7ob02281f
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362, KAKENHI-PROJECT-15K07899
[Journal Article] Multivalency To Inhibit and Discriminate Hexosaminidases2017
- Author(s)
  Alvarez-Dorta D., King D. T., Legigan T., Ide D., Adachi I., Deniaud D., Desire J., Kato A., Vocadlo D., Gouin S. G., Bleriot Y.
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 23 Pages: 9022-9025
- DOI
  10.1002/chem.201701756
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08362
[Journal Article] Strategy for designing selective α-L-rhamnosidase inhibitors: Synthesis and biological evaluation of L-DMDP cyclic isothioureas.2017
- Author(s)
  Miyawaki, S., Hirokami, Y., Kinami, K., Hoshino, M., Minehira, D., Miyamoto, D., Nash, R. J., Fleet, G. W. J., Adachi, I., Kato, A.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 25 (1) Pages: 107-115
- DOI
  10.1016/j.bmc.2016.10.015
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143, KAKENHI-PROJECT-15K08021
[Journal Article] Concise synthesis of calystegine B2 and B3 via intramolecular Nozaki-Hiyama-Kishi reaction.2016
- Author(s)
  Wang, H.Y., Kato, A., Kinami, K., Li, Y.-X., Fleet, G.W.J., Yu, C.-Y.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 14 (21) Pages: 4885-4896
- DOI
  10.1039/c6ob00697c
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Docking study and biological evaluation of pyrrolidine-based iminosugars as pharmacological chaperones for Gaucher disease.2016
- Author(s)
  Atsushi Kato, Izumi Nakagome, Kasumi Sato, Arisa Yamamoto, Isao Adachi, Robert J. Nash, George W. J. Fleet, Yoshihiro Natori, Yasuka Wasuka, Tatsushi Imahori, Yuichi Yoshimura, Hiroki Takahata and Shuichi Hirono
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 14 Pages: 1039-1048
- DOI
  10.1039/c5ob02223a
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05437, KAKENHI-PROJECT-26460143, KAKENHI-PROJECT-25860088
[Journal Article] 3-Azidoazetidines as the first scaffolds for β-amino azetidine carboxylic acid peptidomimetics: azetidine iminosugars containing an acetamido group do not inhibit β-N-acetylhexosaminidases2016
- Author(s)
  Liu, Z., Jenkinson, S. F., Kato, A., Nakagawa, S., Wormald, M. R., Yu, C.-Y., Fleet, G. W. J.
- Journal Title
  
  Tetrahedron Asymm.
  
  Volume: 27(17-18) Pages: 872-881
- DOI
  10.1016/j.tetasy.2016.08.001
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Fluorinated radicamine A and B: synthesis and glycosidase inhibition.2016
- Author(s)
  Li, Y.-X., Iwaki, R., Kato, A., Jia, Y.-M., Fleet, G. W. J., Zhao, X., Xiao, M., Yu, C.-Y.
- Journal Title
  
  Eur. J. Org. Chem.
  
  Volume: 7 Pages: 1429-1438
- DOI
  10.1002/ejoc.201501453
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Structural essentials for β-N-acetylhexosaminidase inhibition by amides of prolines, pipecolic and azetidine carboxylic acids.2016
- Author(s)
  Glawar, A. F. G., Martinez, R. F., Ayers, B. J., Hollas, M. A., Ngo, N. Nakagawa, S., Kato, A., Butters, T. D., Fleet, G. W. J., Jenkinson, S. F.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 14 (44) Pages: 10371-10385
- DOI
  10.1039/c6ob01549b
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] First total synthesis of (+)-broussonetine W: Glycosisdase inhibitory activities of natural product & analogs.2016
- Author(s)
  Song. Y.-Y., Kinami, K., Kato, A., Jia, Y.-M., Li, Y.-X., Fleet, G. W. J., Yu, C.-Y.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 14 (22) Pages: 5157-5174
- DOI
  10.1039/c6ob00720a
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars.2016
- Author(s)
  Qian, B.-C., Kamori, A., Kinami, K., Kato, A., Li, Y.-X., Fleet, G. W. J., Yu, C-.Y.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 14(19) Pages: 4488-4498
- DOI
  10.1039/c6ob00531d
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Gem-difluoromethylated and trifluoromethylated derivatives of DMDP-related iminosugars: synthesis and glycosidase inhibition.2016
- Author(s)
  Li, Y.-X., Kinami, K., Hirokami, Y., Kato, A., Su, J.-K., Jia, Y.-M., Fleet, G. W. J., Yu, C.-Y.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 14(7) Pages: 2249-2263
- DOI
  10.1039/c5ob02474a
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] 3-Fluoro-azetidine carboxylic acids and trans,trans-3,4-difluoroproline as peptide scaffolds: inhibition of pancreatic cancer cell growth by a fluoroazetidine iminosugar.2015
- Author(s)
  Liu, Z., Jenkinson, S. F., Vermaas, T., Adachi, I., Wormald, M. R., Hata, U., Kurashima, Y., Kaji, A., Yu, C,-Y., Kato, A., Fleet, G. W. J.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 80(9) Pages: 4244-4258
- DOI
  10.1021/acs.joc.5b00463
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Synthesis and glycosidase inhibition of australine and its fluorinated derivatives.2015
- Author(s)
  Li, Y.-X., Shimada, Y., Sato, K., Kato, A., Zhang, W., Jia, Y.-M., Fleet, G. W. J., Yu, C.-Y.
- Journal Title
  
  Org. Lett.
  
  Volume: 17(3) Pages: 716-719
- DOI
  10.1021/ol503728e
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Enantiodivergent strategy for the synthesis of polyhydroxylated pyrrolizidines and evaluation of their inhibitory activities against glycosidases2015
- Author(s)
  Minehira, D.*; Okada, T.; Iwaki, R.; Kato, A.; Adachi, I.; Toyooka, N.*
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 56 Pages: 331-334
- DOI
  10.1016/j.tetlet.2014.11.087
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590138
[Journal Article] Design and synthesis of labystegines, hybrid iminosugars from LAB and calystegine, as inhibitors of intestinal α-glucosidases: binding conformation and interaction for ntSI.2015
- Author(s)
  Kato, A., Zhang, Z.-L., Wang, H.-Y., Jia, Y.-M., Yu, C.-Y., Kinami, K., Hirokami, Y., Tsuji, Y., Adachi, I., Nash, R. J., Fleet, G. W. J., Koseki, J., Nakagome, I., Hirono, S.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 80(9) Pages: 4501-4515
- DOI
  10.1021/acs.joc.5b00342
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Fluorinated and conformationally fixed derivatives of L-homoDMDP: synthesis and glycosidase inhibition.2015
- Author(s)
  Li, Yi.-X., Shimada, Y., Adachi, I., Kato, A., Jia, Y.-M., Fleet, G. W. J., Xiao, M., Yu. C.-Y.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 80(10) Pages: 5151-5158
- DOI
  10.1021/acs.joc.5b00571
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Docking and SAR studies of calystegines : binding orientation and influence on pharmacological chaperone effects for Gaucher's disease2014
- Author(s)
  Kato, A., Nakagome, I., Nakagawa, S., Koike, Y., Nash, R. J., Adachi, I., Hirono, S.
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 22 (8) Pages: 2435-2441
- DOI
  10.1016/j.bmc.2014.02.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Synthesis and biological evaluation of α-1-C-4′-arylbutyl-L-arabinoiminofuranoses, a new class of α-glucosidase inhibitors2014
- Author(s)
  Yoshihiro Natori, Toshihiro Sakuma, Yuichi Yoshimura, Kyoko Kinami, Yuki Hirokami, Kasumi Sato, Isao Adachi, Atsushi Kato, Hiroki Takahata
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Pages: 3298-3301
- DOI
  10.1016/j.bmcl.2014.06.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860088
[Journal Article] Synthesis of 1,2-trans-2-acetamido-2-deoxyhomoiminosugars.2014
- Author(s)
  Bleriot, Y., Tran, A. T., Prencipe, G., Jagadeesh, Y., Auberger, N., Zhu, S., Gauthier, C., Zhang, Y., Desire;, J., Adachi, I., Kato, A., Sollogoub, M.
- Journal Title
  
  Org. Lett.
  
  Volume: 16 (21) Pages: 5516-5519
- DOI
  10.1021/ol502929h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors.2014
- Author(s)
  Kato, A., Hirokami, Y., Kinami, K., Tsuji, Y., Miyawaki, S., Adachi, I., Hollinshead, J., Nash, R. J. Kiappes, J. L., Zitzmann, N., Cha, J. K., Molyneux, R. J., Fleet, G. W. J., Asano, N.
- Journal Title
  
  Phytochemistry
  
  Volume: 111 Pages: 124-131
- DOI
  10.1016/j.phytochem.2014.12.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460143
[Journal Article] C-Branched iminosugars :α-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP and isoDAB–L-isoDMDP compared to miglitol and miglustat2013
- Author(s)
  Jenkinson, S. F., Best, D., Saville, A. W., Mui, J., Martinez, R. F., Nakagawa, S., Kunimatsu, T., Alonzi, D. S., Butters, T. D., Norez, C., Becq, F., Blériot, Y. Wilson, F. X., Weymouth-Wilson, A. C., Kato, A., Fleet, G. W. J.
- Journal Title
  
  J. Org. Chem
  
  Volume: 78 (15) Pages: 7373-7776
- DOI
  10.1021/jo4005487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Synthesis of Phenylalkyl Substituted Polyhydroxypiperidines as Potent Inhibitors for α-L-Fucosidases2013
- Author(s)
  Saka, T.; Okaki, T.; Ifuku, S.; Yamashita, Y.; Sato, K.; Miyawaki, S.; Kamori, A.; Kato, A.*; Adachi, I.; Kiria, P. G.; Onomura, O.; Minato, D.; Sugimoto, K.; Matsuya, Y.; Toyooka, N.*
- Journal Title
  
  Tetrahedron
  
  Volume: 69 Pages: 10653-10661
- DOI
  10.1016/j.tet.2013.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590138
[Journal Article] Synthesis of eight stereoisomers of pochonicine : Nanomolar inhibition ofβ-N-acetylhexosaminidases2013
- Author(s)
  Zhu, J. -S., Nakagawa, S., Chen, W., Adachi, I., Jia, Y. -M., Hu, X. -G., Fleet, G. W. J., Wilson, F. X., Nitoda, T., Horne, G., van Well, R., Kato, A., Yu, C. -Y.
- Journal Title
  
  J. Org. Chem
  
  Volume: 78 (20) Pages: 10298-10309
- DOI
  10.1021/jo401694e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] (3R,4S,5R,6R,7S)-3,4,5,7-Tetrahydroxyconid ine, anazetidine analogue of 6,7-diepicastanospermine and aconformationally constrained D-deoxyaltronojirimycin, from L-arabinose2013
- Author(s)
  Martinez, R. F., Araujo, N., Jenkinson, S. F., Nakagawa, S., Kato, A., Fleet, G. W. J.
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 21 (16) Pages: 4813-4819
- DOI
  10.1016/j.bmc.2013.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] General synthesis of sugar-derived azepane nitrones : precursors of azepane iminosugars2013
- Author(s)
  Zhao, W. -B., Nakagawa, S., Kato, A., Adachi, I., Jia, Y. -M., Hu, X. -G., Fleet, G. W. J., Wilson, F. X., Horne, G., Yoshihara, A., Izumori, K., Yu, C. -Y.
- Journal Title
  
  J. Org. Chem
  
  Volume: 78 (7) Pages: 3208-3221
- DOI
  10.1021/jo400130p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] 3-Hydroxyazetidine carboxylic acids : non-proteinogenic amino acids for medicinal chemists2013
- Author(s)
  Jenkinson, S. F., Thompson, A. L., Nakagawa, S., Kato, A., Butters, T. D., Fleet, G. W. J.
- Journal Title
  
  ChemMedChem
  
  Volume: 8 (4) Pages: 658-666
- DOI
  10.1002/cmdc.201200541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Synthesis and biological evaluation of N-(2-fluorophenyl)-2β-deoxyfuconojirimycin acetamide as a potent inhibitor for α-L-fucosidases2013
- Author(s)
  Kato, A.*; Okaki, T.; Ifuku, S.; Sato, K.; Hirokami, Y.; Iwaki, R.; Kamori, A.; Nakagawa, S.; Adachi, I.; Kiria, P. G.; Onomura, O.; Minato, D.; Sugimoto, K.; Matsuya, Y.; Toyooka, N.*
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Pages: 6565-6573
- DOI
  10.1016/j.bmc.2013.08.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590138
[Journal Article] α-1-C-Butyl-1,4-dideoxy-1,4-imino-L-arabinitol as a Second-Generation Iminosugar-Based Oral α-Glucosidase Inhibitor for Improving Postprandial Hyperglycemia2012
- Author(s)
  Kato, A., Hayashi, E., Miyauchi, S., Adachi, I., Imahori, T., Natori, Y., Yoshimura, Y., Nash, R. J., Shimaoka, H., Nakagome, I., Koseki, J., Hirono, S., Takahata, H.
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 55 (23) Pages: 10347-10362
- DOI
  10.1021/jm301304e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059, KAKENHI-PROJECT-22590104, KAKENHI-PROJECT-23590012, KAKENHI-PROJECT-23590127, KAKENHI-PROJECT-23790138
[Journal Article] Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymet hylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol2012
- Author(s)
  Araujo, N., Jenkinson, S. F., Martinez, R. F., Glawar, A. F. G., Wormald, M. R., Butters, T. D., Nakagawa, S., Adachi, I., Kato, A. Yoshihara, A., Akimitsu, K., Izumori, K., Fleet, G. W. J.
- Journal Title
  
  Org. Lett
  
  Volume: 14 (16) Pages: 4174-4177
- DOI
  10.1021/ol301844n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059, KAKENHI-PROJECT-23590127
[Journal Article] α-1-C-Butyl-LAB as a second-generation iminosugar-based oral α-glucosidase inhibitor for improving postprandial hyperglycemia2012
- Author(s)
  Kato, A., Hayashi, E., Miyauchi, S., Adachi, I., Imahori, T., Natori, Y., Yoshimura, Y., Nash, R. J., Shimaoka, H., Nakagome, I., Koseki, J., Hirono, S., Takahata, H
- Journal Title
  
  J. Med. Chem
  
  Volume: 55(23) Pages: 10347-10362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Eight stereoisomers of homonojirimycin from D-mannose2012
- Author(s)
  Lenagh-Snow, G. M. J., Jenkinson, S. F., Newberry, S. J., Kato, A., Nakagawa, S., Adachi, I., Wormald, M. R., Yoshihara, A., Morimoto, K., Akimitsu, K., Izumori, K., Fleet, G. W. J.
- Journal Title
  
  Org. Lett
  
  Volume: 14 (8) Pages: 2050-2053
- DOI
  10.1021/ol3005744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Synthesis of 1-Alkyl-2-deoxyiminofuranoses via The Iridium- catalyzed Intramolecular Cyclization of an Allylic Carbonate2012
- Author(s)
  Natori, Y., Kikuchi, S., Yoshimura, Y., Kato, A., Adachi, I., Takahata, H.
- Journal Title
  
  Heterocycles, 2012, 86, 1401-1417.
  
  Volume: 86 (2) Pages: 1401-1417
- DOI
  10.3987/com-12-s(n)99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059, KAKENHI-PROJECT-22590104, KAKENHI-PROJECT-23790138
[Journal Article] Asymmetric synthesis of 2-propylisofagomine using allylic hydroxy group accelerated ring-closing enyne metathesis.2012
- Author(s)
  Taguchi, T., Imahori, T., Yoshimura, Y., Kato, A., Adachi, I., Kawahara, M., Yamaguchi, K., Takahata, H.
- Journal Title
  
  Heterocycles
  
  Volume: 84 (2) Pages: 929-944
- DOI
  10.3987/com-11-s(p)74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Scalable syntheses of both enantiomers of DNJNAc and DGJNAc from glucuronolactone : The effect of N-alkylation on hexosaminidase inhinition2012
- Author(s)
  Glawar, A. Best, D., Ayers, B., Miyauchi, S., Nakagawa, S., Agulilar-M, M., Fernandez, J. M. G., Mellet, C. O., Crabtree, E. V., Butters, T. D., Wilson, F. X., Kato, A., Fleet, G. W. J.
- Journal Title
  
  Chem. Eur. J
  
  Volume: 18 (30) Pages: 9341-9359
- DOI
  10.1002/chem.201200110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Glycosidase inhibition by all 10 stereoisomeric 2,5-dideoxy-2,5-iminohexitols prepared from the enantiomers of glucuronolactone2012
- Author(s)
  Ayers, B., Ngo, M., Jenkinson, S. F Martínez, R. F., Shimada, Y., Adachi, I., Weymouth-Wilson, A. C., Kato, A., Fleet, G. W. J.
- Journal Title
  
  J. Org. Chem
  
  Volume: 77 (18) Pages: 7777-7792
- DOI
  10.1021/jo301243s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Asymmetric synthesis of 1-alkyl-2-deoxyiminofuranoses via The iridium-catalyzed intramolecular cyclization of an allylic carbonate2012
- Author(s)
  Natori, Y., Kikuchi, S., Yoshimura, Y., Kato, A., Adachi, I., Takahata, H
- Journal Title
  
  Heterocycles
  
  Volume: 86(2) Pages: 1401-1417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Asymmetric synthesis of 2-propylisofagomine using allylic hydroxy group accelerated ring-closing enyne metathesis2012
- Author(s)
  Taguchi, T., Imahori, T., Yoshimura, Y., Kato, A., Adachi, I., Kawahara, M., Yamaguchi, K., Takahata, H
- Journal Title
  
  Heterocycles
  
  Volume: 84(2) Pages: 929-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Azetidine iminosugars from the cyclization of 3,5-di-O-triflates ofα-furanosides and of 2,4-di-O-triflates ofβ-pyranosides derived from glucose2012
- Author(s)
  Lenagh-Snow, G. M. J., Araujo, N., Jenkinson, S. F., Martinez, R. F., Shimada, Y, Yu, C.-Y., Kato, A., Fleet, G. W. J.
- Journal Title
  
  Org. Lett
  
  Volume: 14 (8) Pages: 2142-2145
- DOI
  10.1021/ol300669v
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol2012
- Author(s)
  Araujo, N., Jenkinson, S. F., Martinez, R. F., Glawar, A. F. G., Wormald, M. R., Butters, T. D., Nakagawa, S., Adachi, I., Kato, A.Yoshihara, A., Akimitsu, K., Izumori, K., Fleet, G. W. J
- Journal Title
  
  Org. Lett
  
  Volume: 14(16) Pages: 4174-4177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Looking-glass synergistic pharmacological chaperones: DGJ and L-DGJ from the enantiomers of tagatose2011
- Author(s)
  Jenkinson, S. F., Fleet, G. W. J., Nash, R. J., Koike, Y., Adachi, I., Yoshihara, A., Morimoto, K., Izumori, K., Kato, A
- Journal Title
  
  Org. Lett
  
  Volume: 13(15) Pages: 4064-4067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] The synthesis and biological evaluation of 1-C-alkyl-L-arabinoiminofuranoses, a novel class of α-glucosidase inhibitors2011
- Author(s)
  Yoshihiro Natori, Tatsushi Imahori, Keiichi Murakami, Yuichi Yoshimura, Shinpei Nakagawa, Atsushi Kato, Isao Adachi, Hiroki Takahata
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 21巻 Pages: 738-741
- DOI
  10.1016/j.bmcl.2010.11.112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790138
[Journal Article] Looking-glass synergistic pharmacological chaperones: DGJ and L-DGJ from the enantiomers of tagatose.2011
- Author(s)
  Jenkinson, S. F., Fleet, G. W. J., Nash, R. J., Koike, Y., Adachi, I., Yoshihara, A., Morimoto, K., Izumori, K., Kato, A
- Journal Title
  
  Org. Lett.
  
  Volume: 13 (15) Pages: 4064-4067
- DOI
  10.1021/ol201552q
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Inhibition of non-mammalian glycosidases by azetidine iminosugars derived from stable 3,5-di-O-triflates of pentoses.2011
- Author(s)
  Lenagh-Snow, G. M. J., Araujo, N., Jenkinson, S. F., Rutherford, C., Nakagawa, S., Kato, A., Yu, C.-Y., Weymouth-Wilson, A. C., Fleet, G. W. J
- Journal Title
  
  Org. Lett.
  
  Volume: 13 (21) Pages: 5834-5837
- DOI
  10.1021/ol2024482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590127
[Journal Article] Synthesis, conformational analysis, and evaluation as glycosidase inhibitors of two ether-bridged iminosugars2011
- Author(s)
  Luo, B., Marcelo, F., Desire, J., Zhang, Y., Sollogoub, M., Kato, A., Adachi, I., Canada, F. Jimenez-Barbero, J., Bleriot, Y
- Journal Title
  
  J. Carb. Chem
  
  Volume: 30(7-9) Pages: 641-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590059
[Journal Article] Isolation of iminosugars from Baphia nitida Lodd2008
- Author(s)
  Kato, A., Kato, N., Miyauchi, S., Minoshima, Y., Adachi, I., Ikeda, K., Asano, N., Watson, A.A., Nash, R.J.
- Journal Title
  
  Phytochemistry 69 (5)
  
  Pages: 1261-1265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790086
[Journal Article] Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases2008
- Author(s)
  Minami, Y., Kuriyama, C., Ikeda, K., Kato, A., Takebayashi, K., Adachi, I., Fleet, G.W.J., Kettawan, A., Okamoto, T., Asano, N.
- Journal Title
  
  Bioorg. Med. Chem. 16 (6)
  
  Pages: 2734-2740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790086
[Journal Article] Isolation of iminosugars from Baphia nitida Lodd2008
- Author(s)
  Kato, A., et.al.
- Journal Title
  
  Phytochemistry 69(5)
  
  Pages: 1261-1265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790086
[Journal Article] In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evalution in cell cultures2008
- Author(s)
  Kuriyama, C., Kamiyama, O., Ikeda, K., Sanae, F., Kato, A., Adachi, I., Imahori, T., Takahata, H., Okamoto, T., Asano, N.
- Journal Title
  
  Bioorg. Med. Chem. 16 (15)
  
  Pages: 7330-7336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790086
[Journal Article] Isolation of glycosidase-inhibiting hyacinthacines and related alkaloids from Scilla socialis2007
- Author(s)
  Kato, A., Kato, N., Adachi, I., Hollinshead, J., Fleet, G.W.J., Kuriyama, C., Ikeda, K., Asano, N., Nash, R.J.
- Journal Title
  
  J. Nat. Prod. 70 (6)
  
  Pages: 993-997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790086
[Journal Article] α-1-C-Octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease2006
- Author(s)
  Yu, L., Ikeda, K., Kato, A., Adachi, I., Godin, G., Compain, P., Martin, O., Asano, N.
- Journal Title
  
  Bioorg. Med. Chem. 14
  
  Pages: 7736-7744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790086
[Journal Article] The L-enantiomers of D-sugar-mimicking iminosugars are noncompetitive inhibitors of D-glycohydrolases?2005
- Author(s)
  Asano, N., Ikeda, K., Yu, Li., Kato, A., Takebayashi, K., Adachi, I., et al.
- Journal Title
  
  Tetrahedron Asymm. 16
  
  Pages: 223-229
- Data Source
  KAKENHI-PROJECT-16790080
[Journal Article] Asymmetric synthesis of 1-deoxynojirimycin and its congeners from a common chiral building block.2004
- Author(s)
  Takahata, H., Banba, Y., Sasatani, M., Nemoto, H., Kato, A., Adachi, I.
- Journal Title
  
  Tetrahedron 60
  
  Pages: 8199-8205
- Data Source
  KAKENHI-PROJECT-16790080
[Presentation] Casuarine誘導体の各種グリコシダーゼに対する阻害活性と構造活性相関2022
- Author(s)
  島立優奈、喜瀬真妃、新澤健太、加藤敦
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-21K06451
[Presentation] In silico解析と親和性測定に基づいたlysosomal acid α-glucosidase (GAA)選択特性を有するイミノ糖のデザイン研究2022
- Author(s)
  加藤敦、中込泉、畑瑞希、新澤健太、名取良浩、吉村祐一、田中信忠
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-21K06451
[Presentation] イミノ糖を基盤とした酸性α-グルコシダーゼに対する選択的阻害剤のデザイン研究2021
- Author(s)
  加藤敦、中込泉、畑瑞希、吉村洸亮、名取良浩、吉村祐一、広野修一
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21K06451
[Presentation] ヒメコウゾ (Broussonetia kazinoki)に含まれるbroussonetine MおよびWのグリコシダーゼ阻害活性と誘導体化の試み2019
- Author(s)
  島立優奈、加藤　敦、木南今日子、足立伊佐雄
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08362
[Presentation] Hex A高親和性リガンドのin silico解析とTay-Sachs病に対するファーマコロジカルシャペロン効果の検証2019
- Author(s)
  加藤　敦、中込泉、中川進平、島立優奈、足立伊佐雄、広野修一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08362
[Presentation] MDシミュレーションによるβ-glucocerebrosidase-ケミカルシャペロンα-1-C-tridecyl-DAB複合体の構造安定性解析2019
- Author(s)
  中込泉、加藤　敦、山乙教之、広野修一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08362
[Presentation] 新規ピロリジン型イミノ糖誘導体のデザインとゴーシェ病に対するシャペロン効果について2019
- Author(s)
  島立優奈、加藤　敦、久保萌美、井出大介、足立伊佐雄
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08362
[Presentation] Hex A高親和性リガンドの創製とTay-Sachs病に対するファーマコロジカルシャペロン効果の検証2018
- Author(s)
  加藤　敦、中込　泉、久保萌美、今枝秀貴、足立伊佐雄、広野修一
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K08362
[Presentation] 選択的α-L-rhamnosidase阻害剤のデザイン戦略：L-DMDP cyclic isothioureasの合成と構造最適化2017
- Author(s)
  星野雅子、加藤敦、宮脇章太、広上由季、木南今日子、友原啓介、宮本大樹、足立伊佐雄、豊岡尚樹
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター他
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08021
[Presentation] コンピュータリガンドドッキングと分子動力学シミュレーションによるHexosaminidase A―リガンド複合体の相互作用解析2017
- Author(s)
  中込泉、加藤敦、山乙教之、足立伊左雄、広野修一
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター他
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] ピロリジン型イミノ糖を基盤とした新規GCase高親和性リガンドのデザインとファーマコロジカルシャペロン効果について2016
- Author(s)
  加藤敦、山本亜里紗、友原啓介、足立伊佐雄、渡邊靖香、名取良浩、吉村祐一、中込泉、広野修一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] ピロリジン型イミノ糖を基盤とした新規GCase高親和性リガンドのデザインとファーマコロジカルシャペロン効果について2016
- Author(s)
  加藤敦、山本亜里紗、友原啓介、足立伊佐雄、渡邊靖香、名取良浩、吉村祐一、中込　泉、広野修一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Hexosaminidase Aの高親和性リガンドに対するイン・シリコ相互作用解析2016
- Author(s)
  中込　泉、加藤　敦、山乙　教之、足立伊佐雄、広野修一
- Organizer
  第44回構造活性相関シンポジウム
- Place of Presentation
  京都大学医学部創立百年記念施設
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] イミノ糖を基盤としたGCase高親和性リガンドの創製とファーマコロジカルシャペロン効果について2016
- Author(s)
  加藤敦、中込　泉、佐藤香純、山本亜里紗、足立伊佐雄、広野修一
- Organizer
  第35回糖質学会年会
- Place of Presentation
  高知市文化プラザ　かるぽーと
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Computational study of the interaction of α-1-C-alkyl derivatives of 1,4-dideoxy-1,4-imino-D-arabinitol with β-glucocerebrosidase2015
- Author(s)
  中込　泉、加藤　敦、山乙教之、吉田智喜、足立伊佐雄、広野修一
- Organizer
  第43回構造活性相関シンポジウム
- Place of Presentation
  新潟日報メディアシップ　日報ホール
- Year and Date
  2015-09-27
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Catalytic asymmetric syntheses and biological evaluations of α-1-C-substituted L-iminofuranose derivatives as α-glucosidase inhibitor2015
- Author(s)
  Natori, Y., Kato, A., Adachi, I., Yoshimura, Y.
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Catalytic asymmetric syntheses and biological evaluations of α-1-C-substituted L-iminofuranose derivatives as α-glucosidase inhibitor2015
- Author(s)
  Natori, Y., Kato, A., Adachi, I., Yoshimura, Y.
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08021
[Presentation] In silico study on the interaction of high affinity ligand calystegine B2 with β-glucocerebrosidase2015
- Author(s)
  Nakagome, I., Kato, A., Yoshida, T., Yamaotsu, N., Adachi, I., Hirono, S.
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] Catalytic Asymmetric Syntheses and Biological Evaluations of α-1-C-Substituted L-Iminofuranose Derivatives as α-Glucosidase Inhibitor2015
- Author(s)
  Yoshihiro Natori, Atsushi Kato, Isao Adachi, Yuichi Yoshimura
- Organizer
  2015 環太平洋国際化学会議 (PACIFICHEM 2015)
- Place of Presentation
  ハワイコンベンションセンター(ハワイ州ホノルル)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成と酵素阻害活性評価2015
- Author(s)
  佐久間俊嘉、名取良浩、中川進平、加藤　敦、足立伊佐雄、吉村祐一
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-15K08021
[Presentation] Synthesis and interactions of rhamnose iminosugar mimics with the rhamnose operon, rhamnosidases, and rhamnose isomerase2015
- Author(s)
  Liu, Z., Kelly, C., Yoshihara, A., Izumori, K., Wormald, M., Otero-Casas, J., Estevez-Reino, A., Heap, J., Kato, A., Adachi, I., Jenkinson, S., Fleet, G., Estevez, R.
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08021
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成と酵素阻害活性評価2015
- Author(s)
  佐久間俊嘉、名取良浩、中川進平、加藤　敦、足立伊佐雄、吉村祐一
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成と酵素阻害活性評価2015
- Author(s)
  佐久間　俊嘉，名取　良浩，中川　進平，加藤　敦，足立　伊佐雄，吉村　祐一
- Organizer
  第33回メディシナルケミストリーシンポジウム
- Place of Presentation
  幕張国際研修センター(千葉県千葉市)
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] Calystegine類のβ-glucocerebrosidaseに対する結合親和性とファーマコロジカルシャペロン効果について2014
- Author(s)
  加藤敦、中込泉、中川進平、広野修一、足立伊佐雄
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] トリアゾール環を側鎖に持つD-イミノフラノース誘導体の合成と生物活性評価2014
- Author(s)
  名取良浩、盛　友莉恵、吉村祐一、佐藤香純、加藤　敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] C1位に4-アリールブチル基が置換したイミノ糖誘導体の不斉合成とそのα-グルコシダーゼ阻害活性評価2014
- Author(s)
  名取良浩、佐久間俊嘉、加藤敦a、足立伊佐雄a、吉村祐一
- Organizer
  第53回日本薬学会東北支部大会
- Place of Presentation
  いわき明星大学(福島県いわき市)
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] 1-C-n-ブチル-L-イミノ糖誘導体の触媒的不斉合成とα-グルコシダーゼ阻害活性評価2014
- Author(s)
  佐久間俊嘉、名取良浩、加藤敦、足立伊佐雄、中川進平、吉村祐一
- Organizer
  創薬研究センターシンポジウム－衛生毒性学の最先端研究から創薬への提言－
- Place of Presentation
  東北薬科大学(宮城県仙台市青葉区)
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] β-1-C-n-ブチル-L-イミノ糖誘導体の触媒的不斉合成とα-グルコシダーゼ阻害作用に対する構造活性相関2014
- Author(s)
  佐久間俊嘉、名取良浩、吉村祐一、加藤敦、足立伊佐雄、中川進平、高畑廣紀
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] DGJNAc誘導体の結合親和性とpharmacological chaperone活性について2014
- Author(s)
  中川進平、加藤敦、足立伊佐雄
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Calystegine類のβ-glucocerebrosidaseに対する結合親和性とファーマコロジカルシャペロン効果について2014
- Author(s)
  加藤　敦、中込　泉、中川進平、広野修一、足立伊佐雄
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 新規β-glucocerebrosidase高親和性リガンドcalystegine B_2の結合様式に対するin silico解析2014
- Author(s)
  中込泉、加藤敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] β-1-C-n-ブチル-L-イミノ糖誘導体の触媒的不斉合成とα-グルコシダーゼ阻害作用に対する構造活性相関2014
- Author(s)
  佐久間俊嘉、名取良浩、吉村祐一、加藤　敦、足立伊佐雄、中川進平、高畑廣紀
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 新規β-glucocerebrosidase高親和性リガンドcalystegine B2の結合様式に対するin silico解析2014
- Author(s)
  中込　泉、加藤　敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] トリアゾール環を側鎖に持つD-イミノフラノース誘導体の合成と生物活性評価2014
- Author(s)
  名取良浩、盛友莉恵、吉村祐一、佐藤香純、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の不斉合成とその酵素阻害活性評価2014
- Author(s)
  佐久間俊嘉、名取良浩、中川進平、加藤敦、足立伊佐雄、吉村祐一
- Organizer
  第44回複素環化学討論会
- Place of Presentation
  札幌市民ホール(北海道札幌市中央区)
- Year and Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] トリアゾール環を側鎖に持つD-イミノフラノース誘導体の合成と生物活性評価2014
- Author(s)
  名取良浩、盛友莉恵、吉村祐一、佐藤香純、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] クリックケミストリーを用いたD-イミノフラノース誘導体の合成と酵素阻害活性評価2014
- Author(s)
  名取良浩、盛友莉恵、加藤敦、足立伊佐雄、吉村祐一
- Organizer
  創薬研究センターシンポジウム－衛生毒性学の最先端研究から創薬への提言－
- Place of Presentation
  東北薬科大学(宮城県仙台市青葉区)
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] DGJNAc誘導体の結合親和性とpharmacological chaperone活性について2014
- Author(s)
  中川進平、加藤　敦、足立伊佐雄
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学他
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] コンピュータリガンドドッキングによるα-glucosidase阻害剤α-1-C-Butyl-LABのmaltase及びβ-glucosidaseに対する結合様式解析2013
- Author(s)
  中込泉、小関準、山乙教之、合田浩明、広野修一、加藤敦、林恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 強力なフコシダーゼ阻害活性を有するポリヒドロキシピペリジン誘導体の合成2013
- Author(s)
  岡城徹, 坂知樹, 湊大志郎, 杉本健士, 松谷裕二, 中川進平, 山下侑子, 加藤敦, 足立伊佐雄, 手塚康弘, Peter G. Kirira, 尾野村治, 豊岡尚樹
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590138
[Presentation] 新規β-glucocerebrosidase阻害剤calystegine B_2のインシリコ結合様式解析2013
- Author(s)
  中込泉、加藤敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  第41回構造活性相関シンポジウム
- Place of Presentation
  西宮
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 七員環型イミノ糖の誘導体化とグリコシダーゼ阻害活性2013
- Author(s)
  岩城蓮、加藤敦、中川進平、足立伊佐雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について(第2報)2013
- Author(s)
  加藤敦、林恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、島岡秀行、中込泉、小関準、広野修一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について（第2報）2013
- Author(s)
  加藤　敦、林　恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、島岡秀行、中込　泉、小関　準、広野修一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成2013
- Author(s)
  佐久間俊嘉, 渡邉はるか, 名取良浩, 吉村祐一,中川進平, 加藤敦, 足立伊佐雄, 高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] α-1-C-アルキル-D-アラビノイミノ糖誘導体の触媒的不斉合成とその生物活性2013
- Author(s)
  渡邊靖香、佐久間俊嘉、名取良浩、吉村祐一、佐藤香純、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成2013
- Author(s)
  佐久間俊嘉、渡邊はるか、名取良浩、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] α-1-C-アルキル-D-アラビノイミノ糖誘導体の触媒的不斉合成とその生物活性2013
- Author(s)
  渡邊靖香、佐久間俊嘉、名取良浩、吉村祐一、佐藤香純、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1位に4-アリールブチル基を導入したL-アラビノイミノ糖誘導体の不斉合成と生物活性評価2013
- Author(s)
  名取良浩, 今堀龍志, 吉村祐一, 嶋田陽介, 加藤敦, 足立伊佐雄, 高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] α-1-C-アルキル-D-アラビノイミノ糖誘導体の触媒的不斉合成とその生物活性評価2013
- Author(s)
  渡邊靖香, 佐久間俊嘉, 名取良浩, 吉村祐一, 佐藤香純, 加藤敦, 足立伊佐雄, 高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] 1-C-n-ブチル-L-イミノフラノース誘導体の触媒的不斉合成2013
- Author(s)
  佐久間俊嘉、渡邊はるか、名取良浩、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LAB の特性と生物活性について(第1報)2013
- Author(s)
  足立伊佐雄, 加藤敦, 林恵利奈, 中川進平, 名取良浩, 吉村祐一, 高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について(第1報)2013
- Author(s)
  足立伊佐雄、加藤敦、林恵利奈、中川進平、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について(第1報)2013
- Author(s)
  足立伊佐雄、加藤敦、林恵利奈、中川進平、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] 新規β-glucocerebrosidase阻害剤calystegine B2のインシリコ結合様式解析2013
- Author(s)
  中込　泉、加藤　敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  第41回構造活性相関シンポジウム
- Place of Presentation
  関西学院会館
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] ピロリジン型イミノ糖の構造活性相関に基づいたシャペロン様化合物のデザイン研究2013
- Author(s)
  中川進平、加藤敦、足立伊佐雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について(第2報)2013
- Author(s)
  加藤敦
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LAB の特性と生物活性について(第2報)2013
- Author(s)
  加藤敦, 林恵利奈, 足立伊佐雄, 今堀龍志, 名取良浩, 吉村祐一, 島岡秀行, 中込泉, 小関準, 広野修一, 高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について（第1報）2013
- Author(s)
  足立伊佐雄、加藤　敦、林　恵利奈、中川進平、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1位に4-アリールブチル基を導入したL-アラビノイミノ糖誘導体の不斉合成と生物活性評価2013
- Author(s)
  名取良浩、今堀龍志、吉村祐一、嶋田陽介、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について(第2報)2013
- Author(s)
  加藤敦、林恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、島岡秀行、中込泉、小関準、広野修一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] コンピュータリガンドドッキングによるα-glucosidase 阻害剤α-1-C-Butyl-LAB のmaltase及びβ-glucosidaseに対する結合様式解析2013
- Author(s)
  中込泉, 小関準, 山乙教之, 合田浩明, 林恵利奈, 足立伊佐雄, 今堀龍志, 名取良浩, 吉村祐一, 加藤敦, 高畑廣紀, 広野修一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] フコシダーゼ阻害が期待されるアミド型イミノ糖の合成および活性評価2013
- Author(s)
  伊福翔平・岡城徹・中川進平・加藤敦・足立伊佐雄・Peter G. Kirira・尾野村治・豊岡尚樹
- Organizer
  第４３回複素環化学討論会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-24590138
[Presentation] α-1-C-アルキル-D-アラビノイミノ糖誘導体の触媒的不斉合成とその生物活性2013
- Author(s)
  渡邊靖香、佐久間俊嘉、名取良浩、吉村祐一、佐藤香純、加藤　敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1位に4-アリールブチル基を導入したL-アラビノイミノ糖誘導体の不斉合成と生物活性評価2013
- Author(s)
  名取良浩、今堀龍志、吉村祐一、嶋田陽介、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について（第2報）2013
- Author(s)
  加藤　敦、林　恵利奈、足立伊佐雄、今堀龍志、名取良浩、吉村祐一、島岡秀行、中込　泉、小関　準、広野修一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] 次世代型イミノ糖であるα-1-C-alkyl-LABの特性と生物活性について（第1報）2013
- Author(s)
  足立伊佐雄、加藤　敦、林　恵利奈、中川進平、名取良浩、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] フコシダーゼ阻害が期待されるアミド型イミノ糖の合成および活性評価2013
- Author(s)
  伊福翔平・岡城徹・中川進平・加藤敦・足立伊佐雄・Peter G. Kirira・尾野村治・豊岡尚樹
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590138
[Presentation] Synthesis of glycosidase inhibitors based on bicyclic azetidines for the treatment of cancer2012
- Author(s)
  Martínez, R. F., Araújo, N., Jenkinson, S. F., Kato, A., and Fleet, G. W. J
- Organizer
  26^<th> International Carbohydrate Symposium (ICS2012)
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Synthesis of 1-C-Substituted-L-arabinoiminofuranoses and Evaluation of Biological Activities as Novel Class of α-Glucosidase Inhibitors2012
- Author(s)
  Yoshihiro Natori, Yuichi Yoshimura, Atsushi Kato, Isao Adachi, Shuichi Hirono, Hiroki Takahata
- Organizer
  13^<th> Tetrahedron Symposium - Asia Edition
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] C1位に4-アリールブチル基を導入したL-アラビノイミノ糖誘導体の触媒的不斉合成2012
- Author(s)
  名取良浩、今堀龍志、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] L-アラビノイミノフラノースをベースとした食後過血糖改善薬のデザイン合成研究2012
- Author(s)
  加藤敦, 林恵利奈, 中川進平, 足立伊佐雄, 中込泉, 小関準, 広野修一, 名取良浩, 今堀龍志, 吉村祐一, 高畑廣紀
- Organizer
  第31回糖質学会年会
- Place of Presentation
  鹿児島県鹿児島市
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] C1位に4-アリールブチル基を組み込んだL-アラビノイミノフラノースの触媒的不斉合成と生物活性評価2012
- Author(s)
  名取良浩、吉村祐一、高畑廣紀、嶋田陽介、加藤敦、足立伊佐雄
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] Docking and SAR studies of D- and L-isofagomine isomers as humanβ-glucocerebrosidase inhibitors2012
- Author(s)
  Kato, A., Miyauchi, S., Nakagome, I., Yoshimura, Y., Hirono, S., Takahata, H., Adachi, I
- Organizer
  8th AFMC International Medicinal Chemistry Symposium (AIMECS11)
- Place of Presentation
  Keio, Japan
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Asymmetric synthesis and biological evaluations of 1-alkyl L-arabinoiminofuranoses2012
- Author(s)
  Yoshihiro Natori, Tatsushi Imahori, Yuichi Yoshimura, Atsushi Kato, Isao Adachi, Hiroki Takahata
- Organizer
  第6回武田科学振興財団薬科学シンポジウム
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] C1位に4-アリールブチル基を組み込んだL-アラビノイミノフラノースの触媒的不斉合成と生物活性評価2012
- Author(s)
  名取良浩、吉村祐一、高畑廣紀、嶋田陽介、加藤敦、足立伊佐雄
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Asymmetric Synthesis of α-1-C-Substituted-L-arabinoiminofuranoses and Evaluation of Biological Activities as α-Glucosidase Inhibitors2012
- Author(s)
  Yoshihiro Natori, Yuichi Yoshimura, Atsushi Kato, Isao Adachi, Shuichi Hirono, Hiroki Takahata
- Organizer
  International Symposium for Neuroscience 2013
- Place of Presentation
  宮城県仙台市
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] C1位にアリールブチル基を導入したL-アラビノイミノ糖誘導体の触媒的不斉合成2012
- Author(s)
  名取良浩, 今堀龍志, 吉村祐一, 中川進平, 加藤敦, 足立伊佐雄, 高畑廣紀
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道札幌市
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] Synthesis amd biological evaluation of azetidines derivatives from carbohydrates2012
- Author(s)
  Araújo, N., Martínez, R. F., Lenagh-Snow, G. M. J., Glawar, A. F. G., Jenkinson, S. F., Kato, A., Fleet, G.W.J
- Organizer
  26^<th> International Carbohydrate Symposium (ICS2012)
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Synthesis and biological evaluation of azetidines derivatives from carbohydrates.2012
- Author(s)
  Araujo, N., Martinez, R. F., Lenagh-Snow, G. M. J., Glawar, A. F. G., Jenkinson, S. F., Kato, A., Fleet, G.W.J.
- Organizer
  26th International Carbohydrate Symposium (ICS2012)
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] L-アラビノイミノフラノースをベースとした食後過血糖改善薬のデザイン合成研究2012
- Author(s)
  加藤敦
- Organizer
  第31回糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] C1位に4-アリールブチル基を組み込んだL-アラビノイミノフラノースの触媒的不斉合成と生物活性評価2012
- Author(s)
  名取良浩, 吉村祐一, 高畑廣紀, 嶋田陽介, 加藤敦, 足立伊佐雄
- Organizer
  第38回反応と合成の進歩シンポジウム
- Place of Presentation
  東京都江戸川区
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] Synthesis of glycosidase inhibitors based on bicyclic azetidines for the treatment of cancer.2012
- Author(s)
  Martinez, R. F., Araujo, N., Jenkinson, S. F., Kato, A., and Fleet, G. W. J
- Organizer
  26th International Carbohydrate Symposium (ICS2012)
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] L-アラビノイミノフラノースをベースとした食後過血糖改善薬のデザイン合成研究2012
- Author(s)
  加藤敦、林恵利奈、中川進平、足立伊佐雄、中込泉、小関準、広野修一、名取良浩、今堀龍志、吉村祐一、高畑廣紀
- Organizer
  第31回糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] N-アセチルヘキソサミニダーゼを標的とした1-N型イミノ糖のデザイン研究2012
- Author(s)
  嶋田陽介、加藤敦、佐藤香純、中川進平、足立伊佐雄
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Sucrase及びIsomaltaseへのLAB化合物の結合様式に関する理論的研究2012
- Author(s)
  小関準、中込泉、足立伊佐雄、加藤敦、広野修一
- Organizer
  第40回構造活性相関シンポジウム
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] C1位にアリールブチル基を導入したL-アラビノイミノ糖誘導体の触媒的不斉合成2012
- Author(s)
  名取良浩，今堀龍志，吉村祐一，中川進平，加藤敦，足立伊佐雄，高畑廣紀
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道札幌市北海道大学
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] LABNAcを中心としたβ-N-acetyl-hexosaminidaseに対する構造活性相関とPC活性について2012
- Author(s)
  中川進平、加藤敦、嶋田陽介、足立伊
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] Synthesis of Novel Iminosugar Derivatives with Inhibitory Effects on α-Fucosidase2012
- Author(s)
  Toru Okaki, Tomoki Saka, Daishiro Minato, Kenji Sugimoto, Yuji Matsuya, Shinpei Nakagawa, Yukiko Yamashita, Atsushi Kato, Isao Adachi, Peter G. Kirira, Osamu Onomura, Naoki Toyooka
- Organizer
  The 12th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12)
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-24590138
[Presentation] Isofagomine類のβ-glucocerebrosidaseに対する結合親和性と構造活性相関について2012
- Author(s)
  加藤敦、中川進平、足立伊佐雄、中込泉、広野修一、吉村祐一、高畑廣紀
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] C1位アルキルL-アラビノイミノフラノース誘導体の触媒的不斉合成とその生物活性2011
- Author(s)
  名取良浩、今堀龍志、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] Catalytic Enantioselective Synthesis and Biological Evaluation of C1-Alkyl L-arabino-Iminofuranose Derivatives as α-Glycosidase Inhibitor2011
- Author(s)
  Yoshihiro Natori, Tatsushi Imahori, Keichi Murakami, Yuichi Yoshimura, Shinpei Nakagawa, Atsushi Kato, Isao Adachia , Hiroki Takahata
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  東京都新宿区
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] Catalytic Enantioselective Synthesis and Biological Evaluation of C1-Alkyl L-arabino-Iminofuranose Derivatives as α-Glycosidase Inhibitor2011
- Author(s)
  Yoshihiro Natori，Tatsushi Imahori，Keichi Murakami，Yuichi Yoshimura，Shinpei Nakagawaa，Atsushi Katoa，Isao Adachia, Hiroki Takahata
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] フコシダーゼ阻害活性が期待されるイミノ糖誘導体の合成研究2011
- Author(s)
  坂知樹、杉本健士、松谷裕二、中川進平、山下侑子、加藤敦、足立伊佐雄、豊岡尚樹
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1置換L-アラビノイミノ糖誘導体の触媒的不斉合成2011
- Author(s)
  名取良浩、今堀龍志、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] C1位アルキルL-アラビノイミノフラノース誘導体の触媒的不斉合成とその生物活性評価2011
- Author(s)
  名取良浩，今堀龍志，吉村祐一，中川進平，加藤敦，足立伊佐雄，高畑廣紀
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪府大阪国際センター
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] C1位アルキルL-アラビノイミノフラノース誘導体の触媒的不斉合成とその生物活性2011
- Author(s)
  名取良浩、今堀龍志、吉村祐一、中川進平、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] 1位アルキルL-アラビノイミノフラノース誘導体の触媒的不斉合成とその生物活性評価2011
- Author(s)
  名取良浩, 今堀龍志, 吉村祐一, 中川進平, 加藤敦, 足立伊佐雄, 高畑廣紀
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] Docking and SAR studies of D- and L-isofagomine isomers as human β-glucocerebrosidase inhibitors2011
- Author(s)
  Kato, A., Miyauchi, S., Nakagome, I., Yoshimura, Y., Hirono, S., Takahata, H., Adachi, I.
- Organizer
  8th AFMC International Medicinal Chemistry Symposium (AIMECS11)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] L-アラビノース型アルキルイミノフラノース誘導体の触媒的不斉合成と薬理活性評価2011
- Author(s)
  高畑廣紀，今堀龍志，名取良浩，村上景一，吉村祐一，中川進平，加藤敦，足立伊佐雄
- Organizer
  第36回反応と合成の進歩シンポジウム
- Place of Presentation
  愛知県名古屋市ウインクあいち
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] D-およびL-isofagomine類の合成とグリコシダーゼ阻害活性2011
- Author(s)
  加藤敦、宮内沙織、中川進平、足立伊佐雄、中込泉、広野修一、吉村祐一、高畑廣紀
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡
- Data Source
  KAKENHI-PROJECT-23590127
[Presentation] L-アラビノース型アルキルイミノフラノース誘導体の触媒的不斉合成と薬理活性評価2011
- Author(s)
  高畑廣紀, 今堀龍志, 名取良浩, 村上景一, 吉村祐一, 中川進平, 加藤敦, 足立伊佐雄
- Organizer
  第36回反応と合成の進歩シンポジウム
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2011-11-01
- Data Source
  KAKENHI-PROJECT-23790138
[Presentation] Pharmacological chaperone活性を有するL型イミノ糖の可能性について2010
- Author(s)
  小池有理子、加藤敦、足立伊佐雄、石井達
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590059
[Presentation] ピペリジン型イミノ糖を用いた糖尿病治療薬の開発研究2009
- Author(s)
  宮内沙織、加藤敦、今堀龍志、高畑廣紀、足立伊佐雄
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18790086
[Presentation] ウロン酸型アザ糖類の合成とβ-glucuronidase阻害活性の評価2008
- Author(s)
  大原千明、高橋遼子、宮川達徳、吉村祐一、高畑廣紀、加藤敦、足立伊佐雄
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790086
[Presentation] 5-アザウロン酸類の合成とβ-グルクロニダーゼ阻害に関する構造活性相関研究2008
- Author(s)
  吉村祐一、大原千明、加藤敦、足立伊佐雄、高畑廣紀
- Organizer
  第27回メディシナルケミストリーシンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18790086
[Presentation] グルコセレブロシダーゼ阻害剤の構造活性相関とシャペロニング活性について2006
- Author(s)
  浅野直樹、虞亮、池田京子、加藤敦、足立伊佐雄、Philippe Compain、Olivier R. Martin、石井達、樊建強
- Organizer
  日本糖質学会第26回年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18790086
[Presentation] 新規hyacinthacine類の構造とグリコシダーゼ阻害活性2006
- Author(s)
  加藤敦、足立伊佐雄、大畠京子、浅野直樹、栗山ちなみ、加藤典子、Robert, J. Nash
- Organizer
  日本糖質学会第26回年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18790086
[Presentation] Biological Properties of D- and L-1-deoxyiminosugars2006
- Author(s)
  Atsushi Kato, Noriko Kato, Isao Adachi, Hiroki Takahata, and Naoki Asano
- Organizer
  Rare Sugar Congress
- Place of Presentation
  Takamatsu, Kagawa, Japan
- Data Source
  KAKENHI-PROJECT-18790086
[Presentation] α-glucosidase 阻害剤 α-1-C-Butyl-LAB のイソマルターゼに対する結合様式解析
- Author(s)
  中込　泉、小関　準、加藤　敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] β-glucocerebrosidaseに対する高親和性リガンドcalystegine B2類縁体の計算化学的相互作用解析
- Author(s)
  中込　泉、加藤　敦、山乙教之、足立伊佐雄、広野修一
- Organizer
  第42回構造活性相関シンポジウム
- Place of Presentation
  くまもと森都心プラザ
- Year and Date
  2014-11-13 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-26460143
[Presentation] 1-C-n-ブチル-L-イミノ糖誘導体の触媒的不斉合成と α-グルコシダーゼ阻害作用に対する構造活性相関
- Author(s)
  佐久間俊嘉, 名取良浩, 加藤敦, 足立伊佐雄, 中川進平, 吉村祐一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学(兵庫県神戸市中央区)
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] C1 位に 4-アリールブチル基が置換したイミノフラノース誘導体の不斉合成とその酵素阻害活性評価
- Author(s)
  名取良浩, 佐久間俊嘉, 木南今日子, 加藤敦, 足立伊佐雄, 吉村祐一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザインクリエイティブセンター神戸(兵庫県神戸市中央区)
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25860088
[Presentation] GCase高親和性リガンドである1-N型イミノ糖の結合親和性とファーマコロジカルシャペロン効果について
- Author(s)
  加藤敦、山本亜里紗、中川進平、足立伊佐雄、中込泉、広野修一
- Organizer
  第33回糖質学会年会
- Place of Presentation
  名古屋大学豊田講堂
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-26460143

1. ADACHI Isao (30151070)

# of Collaborated Projects: 8 results

# of Collaborated Products: 92 results
2. TAKAHATA Hiroki (00109109)

# of Collaborated Projects: 5 results

# of Collaborated Products: 60 results
3. NATORI Yoshihiro (50584455)

# of Collaborated Projects: 5 results

# of Collaborated Products: 38 results
4. ISHII Satoshi (00222935)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. HIRONO Shuichi (30146328)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
6. TOYOOKA Naoki (10217565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. ASANO Naoki (50121265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIMURA Yuichi (00230813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
9. 大内秀一 (30275606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中込泉 (30237242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. IMAHORI Tatsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 田中信忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kato Atsushi 加藤 敦

加藤 敦 カトウ アツシ

KATO Atsushi 加藤 敦

Research Projects

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変異酵素の構造安定化に基づく機能性シャペロン化合物の創製とポンペ病治療への応用Principal Investigator

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Analyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay-Sachs diseasePrincipal Investigator

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Design and synthesis of iminosugar-based pharmacological chaperone as a structure stabilizing agent for mutation enzymePrincipal Investigator

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Design, synthesis, and biological evaluation of iminosugars as pharmacological chaperone for Gaucher diseasePrincipal Investigator

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Development of new concept drugs against lysosome disease base on enzyme structures stabilized effectsPrincipal Investigator

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変異タンパク質の分子生物学的特性に基づいたリソソーム病治療薬の開発Principal Investigator

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Kato Atsushi 加藤敦

加藤敦カトウアツシ

KATO Atsushi 加藤敦