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Kadowaki Takashi  門脇 孝

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KADOWAKI Takashi  門脇 孝

門脇 孝

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Researcher Number 30185889
Other IDs
External Links
Affiliation (Current) 2025: 東京大学, 医学部附属病院, 客員研究員
Affiliation (based on the past Project Information) *help 2019 – 2021: 東京大学, 医学部附属病院, 客員研究員
2016 – 2017: 東京大学, 医学部附属病院, 教授
2003 – 2014: The University of Tokyo, Faculty of Medicine, Professor, 医学部附属病院, 教授
2013: 東京大学, 医学部附属病院, 教授(移行)
2011: 東京大学, 医学部, 教授 … More
2010 – 2011: The University of Tokyo, 医学部・附属病院, 教授
2007 – 2009: 東京大学, 大学院・医学系研究科, 教授
2008: 東大, 医学部附属病院, 教授
2007 – 2008: The University of Tokyo, Faculty of Medicine, Professor
2006 – 2007: 東京大学, 医学部, 教授
2006: 東京大学, 医学部付属病院, 教授
2006: National Institute of Health and Nutrition, Clinical Nutrition Program, Director, 臨床栄養プログラム, リーダー
2006: 独立行政法人国立健康・栄養研究所, 臨床栄養プログラム, 部長
2005 – 2006: 東京大学, 大学院医学系研究科, 教授
2005: 独立行政法人国立健康・栄養研究所, 応用栄養学研究部, 部長
2004: University of Tokyo Hospital, Department of Metabolic Diseases, Professor, 医学部附属病院糖尿病・代謝内科, 教授
2004: Tokyo University, Internal Medicine, Professor, 大学院・医学系研究科, 教授
2003 – 2004: 東京大学, 医学部・附属病院, 教授
2001 – 2003: 東京大学, 大学院・医学系研究科, 助教授
2001 – 2002: University of Tokyo, Faculty of Medicin, Associate Professor, 医学部附属病院, 助教授
2000 – 2001: University of Tokyo, Lecturer Facuolty of Medicin, 医学部・附属病院, 助教授
2000: 東京大学, 医学系大学院, 助教授
1999: 東京大学, 医学部・付属病院, 講師
1998 – 1999: 東京大学, 医学系大学院, 講師
1998 – 1999: 東京大学, 医学部附属病院, 講師
1997 – 1999: University of Tokyo, Lecturer, 医学部・附属病院, 講師
1997: 東京大学, 医学部, 講師
1996: University of Tokyo.Assistant, 医学部・附属病院・第三内科, 助手
1996: 東京大学, 医学部附属病院, 講師
1995: University of Tokyo, Assistant, 医学部・附属病院, 助手
1991 – 1995: 東京大学, 医学部(病), 助手
1992 – 1994: 東京大学, 医学部, 助手
1992: 東京大学, 医学部・(病)(内科学), 助手
1991: 東京大学, 医学部・(病), 助手
1991: 東京大学, 医学部附属病院, 助手
1986: 東京大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
内分泌・代謝学 / Metabolomics / Metabolomics / Biological Sciences / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Biological Sciences
Except Principal Investigator
Metabolomics / 内分泌・代謝学 / Metabolomics / Clinical nursing … More / Orthopaedic surgery / Biological Sciences / Applied pharmacology / Orthopaedic surgery / Ophthalmology / Circulatory organs internal medicine / Applied genomics Less
Keywords
Principal Investigator
インスリン抵抗性 / アディポネクチン / 糖尿病 / NIDDM / PPARγ / 肥満 / 罹患同胞対法 / 2型糖尿病 / IRS-1 / insulin resistance … More / obesity / アディポネクチン受容体 / PPAR / 脂肪細胞 / 全ゲノムマッピング / PI3キナーゼ / diabetes / Common NIDDM / 健康長寿 / 受容体 / アディポカイン / 組織内中性脂肪含量 / レプチン / 転写共役因子 / 多因子病 / 発生工学 / IRS-2 / 候補遺伝子アプローチ / MAPキナーゼ / インスリン作用 / インスリン受容体 / receptor / adipokine / AMP kinase / AMPキナーゼ / 動脈硬化 / SNP / Pro12Ala遺伝子多型 / PPARγアンタゴニスト / PPARγヘテロ欠損マウス / 罹患同胞対 / インスリン感受性 / インスリン分泌低下 / 遺伝子マッピング / UCP / 候補遺伝子 / glucokinase / 糖尿病モデル動物 / DNAチップ / 遺伝子欠損マウス / 脂肪酸燃焼 / 肥大脂肪細胞 / 一塩基多型 / β3アドレナリン受容体 / 1塩基多型(SNP) / グリセロールリン酸シャトル / NADHシャトル / グルコキナーゼ / グルコース応答性インスリン分泌 / インスリン分泌不全 / 糖尿病合併症 / 認知症 / gene targeting / Diabetes / nuclear receptors / glucose uptake / fatty acid oxidation / adiponectin resistance / adiponectin receptors / 脂質代謝異常 / 核内受容体型転写因子 / 糖取り込み / アディポネクチン抵抗性 / adiponectin / affected sib pair / Haplotype / 全ゲノムスキャン / 個人情報匿名化 / 連鎖不平衡 / 相関解析 / ハプロタイプ / 15-deoxy-12.14-PGJ2 / HPLC / small siza adipocytes / thiazolidinediones / adipocyte differentiation / endogenous PPARγ ligands / 3T3L1脂肪細胞 / 内因性リガンド / CBP / アポトーシス / プロスタグランディン / 脂肪細胞分化 / Pro12Ala polymorphism / PPARγ antagonist / Adiponectin / DNA chip / Insulin resistance / Obesity / High-fat diet / Heterozygous PPARγ deficient mice / Retinoid X受容体アンタゴニスト / Creトランスジェニックマウス / floxマウス / PPARγアンタゴニスト(HX531) / DNAチップ技術 / 高脂肪食 / β2 adrenergic receptor / thrifty genes / high-fat diet / susceptibility loci / affected sib-pair analysis / a polygenic, multifactorial disorder / type 2 diabetes / 疾患感受性 / ゲノムマッピング / アミリン / ミトコンドリアDNA / B2アドレナリン受容体 / PI3-kinase / NADH shuttle / β-cell / knockout mice / ミトコンドリア・グリセロールリン酸脱水素酵素 / リンゴ酸・アスパラギン酸シャトル / 遺伝子ノックアウトマウス / PI3キナーゼp85α調節サブユニット欠損マウス / 低血糖 / グリセロールリン酸シャトル欠損マウス / インスリン依存的糖輸送 / IRS-2欠損マウス / 病態モデル / PPARgamma / beta3 adrenergic receptor / candidate genes / whole genome mapping / sib pair analysis / 原因遺伝子 / NIDDM2 / NIDDM1 / マイクロサテライトマーカー / polygenic disease / insulin action / genetic reconstitution of NIDDM / insulin secretory defect / genetic engineering / シーンターゲティング / グルユキナーゼ / トランスジェニックマウス / 多因子遺伝 / 疾患モデル動物 / 生体分子医学 / 細胞内シグナル伝達 / エネルギー代謝 / AdipoR活性化薬 / カロリー制限 / 寿命 / 脂質代謝 / 糖代謝 / AdipoR / インスリン / エネルギー浪費 / 組織特異的遺伝子改変動物 / 脂肪萎縮 / レプチン感受性 / 分化 / RXRアンタゴニスト / 糖尿病感受性遺伝子 / PRARγ / PPARγ2Pro12Ala多型 / グリコース応答性インスリン分泌 / ピルビン酸 / TCA回路 / 膵島 / GPシャトル欠損マウス / mGPDH欠損マウス / ミトコンドリア型GPDH / インスリン分泌 / 膵β細胞 / PDE3B / Aktキナーゼ / 粗面小胞体 / インスリン含量 / wortmannin / インスリン受容体基質 / 骨格筋グリコーゲン合成酵素 / common NIDDM / ErbB2 / JAKキナーゼ / 細胞増殖 / 乳癌 / プロラクチン / 成長ホルモン / 蛋白チロシンリン酸化 / 膵細胞 / ミトコンドリア異常 / 3243変異 / ras / Grb2 / ASH / シグナル伝達 / IRS-1遺伝子異常 / ミトコンドリア遺伝子異常 / グルコキナーゼ遺伝子異常 / C末端ドメイン / 膜直下ドメイン / チロシンキナーゼ / 遺伝子変異 / インスリン受容体異常症 … More
Except Principal Investigator
糖尿病 / インスリン抵抗性 / IRS-2 / PPARγ / インスリン受容体 / diabetes / アディポネクチン / 肥満 / インスリン受容体基質 / インスリン / adiponectin / insulin resistance / シグナル伝達 / 脂肪細胞 / AMPキナーゼ / 動脈硬化 / 遺伝子 / IRS-1 / insulin / レプチン / IRS / アディポカイン / PPAR / 膵β細胞 / チアゾリジン誘導体 / インスリン作用 / 高脂肪食 / atherosclerosis / 破骨細胞 / 骨芽細胞 / 骨粗鬆症 / 骨 / ノックアウトマウス / obesity / SNP / 2型糖尿病 / グルコキナーゼ / チロシンキナーゼ / 食品 / Akt / Stra13 / VEGF / Rho-kinase / TGF-beta / PDGF / Sp1 / PPARgamma / KDR / glucokinase / high-fat diet / insulin secretion / SREBP-1c / インスリン分泌 / OPLL / ttw / insulin receptor / SREBP-1 / bone / 軟骨 / IGF / diabetes mellitus / SNPs / 相関解析 / leptin / adipocyte / insulin receptor substrate / メタボリックシンドローム / 開口放出 / 脂質 / 受容体 / 脂肪肝 / レプチン抵抗性 / 発生工学 / IRS-3 / 高インスリン血症 / 自己リン酸化 / 生体機能利用 / 農林水産物 / エネルギー・糖質代謝異常 / 糖代謝異常 / 糖質代謝異常 / エネルギー / トランスレーショナルリサーチ / 薬理学 / 細菌 / Pancreatic β cells / Signal Transduction / Diabetes Melitus / 膵ベータ細胞 / cytokine / type-2 helper T cell / intestinal mucosal immune system / nicotinic acetylcholine receptor s / oxazolone / ulcerative Colitis / ニコチン受容体 / サイトカイン / Th2 / 腸管粘膜免疫系 / ニコチン性アセチルコリン受容体 / オキサゾロン / 潰瘍性大腸炎 / promoter / adipokine / プロモーター / bone marrow cells, macrophage / endothelial cell-specific IRS-2 knockout mice / insulin signaling / 骨髄細胞・マクロファージ / 血管内皮細胞特異的IRS-2欠損マウス / インスリンシグナル / Chronic Diseases / Standardization / Guideline / Outcomes Measurement / Self-Management / Quality Assurance in Medical Care / Evidence / Diabetes Mellitus / アウトソーシング / AADE / 糖尿病予防 / 質の保証 / 糖尿病教育 / 科学的根拠 / 慢性疾患 / 標準化 / ガイドライン / アウトカム指標 / セルフマネジメント / 医療の質保証 / エビデンス / Apoptosis / Knockout mouse / Osteoclast / Osteoblast / Osteoporosis / Bone mineral density / Bone / 軟骨内骨化 / 石灰化 / 成長板 / アポトーシス / 骨密度 / High Fat Diet / β cell proliferation / pancreatic β cell / 増殖 / β細胞の増殖 / fat cell / signal transduction / gene / exocytosis / pancreatic beta-cells / Palliative care team / Elderly patient / Discharge planning / Quality index of nursing / Decubitus ulcers prevention / Diabetes onset prevention / Diabetes onset risk recognition / Type 2 diabetes mellitus / 緩和ケアチーム / 高齢患者 / 退院支援 / 看護の質指標 / 褥瘡予防 / 糖尿病発症予防 / 糖尿病発症リスク認知 / Hyalocyte / SU5416 / HIF-1 / Fibrinogen / VPF / 硝子体細胞 / 血管内皮増殖因子 / nitric oxide / exercise capacity / exercise training / metabolic taclors / coronary artery disease / 高脂血症 / 一酸化窒素(NO) / 運動耐容能 / 運動療法 / 代謝因子 / 狭心症 / AMP kinase / islet triglyceride content / DNA microarray / 中性脂肪含量 / metabolic syndrome / レプチン抵抗性改善薬 / 代謝症候群 / affected sib pair / Haplotype / 連鎖不平衡 / physiological activity / microarray / genes / applied animal / アディポネクチン受容体 / CBP / 遺伝子欠損マウス / 生理活性 / マイクロアレイ / 応用動物 / thiazolidine / adipocytes / resistance / polymorphism / cytatin 10 / nucleotide pyrophosphatase(NPPS) / 骨髄 / PPAR-γ / ゲノム / ES細胞 / 脂肪 / 老化 / ポリモルフィズム / cystatin 10 / ヌクレオチドピロリン酸(NPPS) / fatty liver / leptin resistance / osteoblast / osteoporosis / IGF-I / IRS-1,-2 / 骨再生 / 骨折 / 再生 / association analysis / gene structure / gene function / genetic analysis / multifactorial disease / 多遺伝子疾患 / 原因遺伝子解析 / 遺伝子構造 / 遺伝子機能 / 遺伝子解析 / 多因子疾患 / thiazolidinedione / IRS proteins / knockout mice / transgenic mice / PI3キナーゼ / IRS蛋白 / トランスジェニックマウス / thiazolidinedione derivatives / トログリタゾン / 抗糖尿病遺伝子 / 抗肥満遺伝子 / チアゾリジニン誘導体 / TNFα / IRS-1 deficient mice / inculin receptor / insulin action / 欠損マウス / インスリン受容体基質1,2 / IRS-1欠損マウス / インスリン受容体基質1欠損マウス / ホスホチロシン抗体 / 炎症 / カルモジュリン依存性キナーゼ / lRS-2 / 代償性肥大 / CaMK / CREB / バイオテクノロジー / 遺伝子多型 / 動脈硬化症 / 糖代謝 / 血管内皮細胞 / インスリン受容体基質-2 / 遺伝学 / QOL / 看護学 / 療養行動 / 予防行動 / 評価尺度 / Quality of Life / 再生医学 / アゴニスト / AdipoR / 糖 / 発言制御 / 好中球エラスターゼ / ベータセルリン / HNF-4α / adiponectin receptors / hepatic lipid content / UCP1 / CYP2C9 / Resistin / UCP2 / TCF7L2 / AMPK / HNF4α / CPT1A / レジスチン / HHEX遺伝子 / TCF7L2遺伝子 / 関連解析 / cumulative risk / KCNQ1遺伝子 / ゲノムワイド関連解析 / 遺伝因子 / 予測モデル / 候補遺伝子 / GWAS / KCNQ1 / positional cloning / 遺伝的背景 / GLUT2 / Pdx1 / STEBP-1 / 脂質代謝 / PPARγのリガンド / PPARファミリー / 高血圧 / 接着斑 / 細胞遊走 / 細胞接着 / SH2蛋白質 / ras / PCR / 難聴 / 橋本病 / バセドウ病 / 自己免疫 / ミトコンドリア / インスリン非依存性糖尿病 / 遺伝子変異 / ヘリックス・ループ・ヘリックス構造 / 転写因子 / 転写制御機構 / SHC / SH-2ドメイン / PI3-キナーゼ / EGF受容体 / インスリン受容体遺伝子 / transphorylation仮説 / チロシンキナ-ゼ / インスリン受容体異常症 / MAPキナ-ゼ / IRSーI / GAP / PIー3キナ-ゼ Less
  • Research Projects

    (82 results)
  • Research Products

    (880 results)
  • Co-Researchers

    (131 People)
  •  New developments in basic and applied adiponectin research toward reduction of dementia risk and realization of healthy longevityPrincipal Investigator

    • Principal Investigator
      Kadowaki Takashi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      The University of Tokyo
  •  The investigation and analysis for developing next-generation functional foods against lifestyle-related diseases

    • Principal Investigator
      Iwabu Miki
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Hepatic glucose and lipid homeostasis in type 2 diabetes with obesity

    • Principal Investigator
      Kubota Naoto
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Comprehensive and expansive research of the universal metabolic regulation mechanisms for healthspanPrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi, 門脇 孝
    • Project Period (FY)
      2014 – 2019
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Pathophysiological roles of adipokines in the regulation of gut microbiota in life-style related diseases

    • Principal Investigator
      YAMAUCHI TOSHIMASA
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Building and establishing platform technologies for Structure Based Drug Design targeting AdipoR

    • Principal Investigator
      Iwabu Miki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  健康長寿のための普遍的代謝調節経路の包括的研究Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  健康長寿のための普遍的代謝調節経路の包括的研究Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Exploring a novel therapeutic strategy for obesity-induced diabetes by suppressing Class IB PI3-kinase activity

    • Principal Investigator
      UEKI Kohjiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  The physiological and pathophysiological role of IRS-1 and IRS-2 in the liver

    • Principal Investigator
      KUBOTA Tetsuya
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      National Institute of Health and Nutrition
  •  Integrated elucidation of metabolic pathway in the physiology and pathologyPrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  代謝制御機構の統合的理解とその破綻Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Molecular biology of pancreatic islet β cell proliferation and failure

    • Principal Investigator
      OHSUGI Mitsuru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Study for the role of PI 3kinase in proliferation, regeneration and insulin secretion of pancreatic beta cells

    • Principal Investigator
      UEKI Kohjiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  糖尿病患者の療養関連QOLの向上とその血縁者の予防行動促進に関する研究

    • Principal Investigator
      KAZUMA Keiko
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical nursing
    • Research Institution
      The University of Tokyo
  •  The roles of insulin receptor substrate-2 in the regulation of glucosehomeostasis and atherosclerosis

    • Principal Investigator
      KUBOTA Naoto
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Clarification of developing metabolic syndrome by using expressionanalysis of human visceral adipose tissue

    • Principal Investigator
      HARA Kazuo
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  アディポネクチン受容体アゴニストの植物からの探索と糖尿病の根本的治療薬・食品開発

    • Principal Investigator
      山内 敏正
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Physiological and pathophysiological roles ofAdiponectin receptors and identification of molecular targets for treatment of life-style related diseasesPrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Identification of transcription factor which regulates obesity-linked downregulation of adiponectin gene and development of treatment modality for metabolic syndrome

    • Principal Investigator
      YAMAUCHI Toshimasa
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Pathophysiological Role of Cholinergic Anti-inflammatory Pathway via Nicotinic Acetylcholine Receptors in Experimental Ulcerative Colitis

    • Principal Investigator
      KADOWAKI Makoto
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      University of Toyama
  •  Molecular Mechanisms on Pancreatic β cell Proliferation

    • Principal Investigator
      MITSURU Ohsugi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Identification and clinical application of susceptibility genes for diabetes mellitus.

    • Principal Investigator
      KASUGA Masato
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  抗生活習慣病因子アディポネクチンの受容体アゴニスト・発現増加剤・切断活生化剤探索

    • Principal Investigator
      山内 敏正
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  肝臓におけるSTAT3/SOCS3経路の調節による新しい糖脂質代謝改善療法の開発

    • Principal Investigator
      植木 浩二郎
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  アディポネクチンのインスリン分泌作用における機能・役割の解明

    • Principal Investigator
      寺内 康夫
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      Yokohama City University
  •  Analysis of function and signal transduction pathway of resistin using genetically-engineered animals

    • Principal Investigator
      TERAUCHI Yasuo
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Yokohama City University
  •  Dissection of the role of IRS family proteins in the growth and development of pancreatic β cells

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  The elucidation of regulation of Bone Metabolism by Akt1

    • Principal Investigator
      HARA Yukinori
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Decide on Practical Guideline for the Diabetes Self-Management Education by Using Outcomes Measurement.

    • Principal Investigator
      MORIKAWA Hiroko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical nursing
    • Research Institution
      University of Fukui
  •  Insulin signaling in endothelial cells (insulin receptor substrate) and atherosclerosis

    • Principal Investigator
      KUBOTA Tetsuya, 岩部 美紀
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      National Institute of Health and Nutrition
  •  Physiological and pathophysiological roles and signal transduction of adiponectin receptorsPrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  A study about an effective medical offer by prevention function display of hospital nursing

    • Principal Investigator
      KAZUMA Keiko
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Clinical nursing
    • Research Institution
      The University of Tokyo
  •  Differentiation, proliferation, and function of pancreatic beta-cells

    • Principal Investigator
      YAMAUCHI toshimasa
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  CBPヘテロ欠損マウスを用いたレプチン非依存性の新規エネルギー・糖・脂質代謝調節経路の同定Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  IRS-2次損マウスの糖尿病重症度に遺伝子のマッピング、同定

    • Principal Investigator
      TERAUCHI Yasuo
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Physiological and pathophysiological roles of adiponectin and AdipoR1/R2

    • Principal Investigator
      YAMAUCHI Toshimasa, 寺内 康夫
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Identification of type 2 diabetes susceptibility genes in the Japanese population by linkage disequilibrium mapping in the chromosomal regions harboring type 2 diabetes susceptibility genes

    • Principal Investigator
      HARA Kazuo
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied genomics
    • Research Institution
      The University of Tokyo
  •  Mechanism of insulin resistance and strategy of treatment

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  Analysis of molecular mechanisms for impaired insulin secretion and beta-cell hyperplasia caused by lipotoxicity

    • Principal Investigator
      TERAUCHI Yasuo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Effect of exercise training on metabolism and atherosclerosis in patients with diabettus mellitus and coronary artery diseases.

    • Principal Investigator
      MATSUMOTO Akihiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Investigation of the mechanism of diabetic macular edema

    • Principal Investigator
      HATA Yasuaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      KYUSHU UNIVERSITY
  •  The pathophysiological roles of adiponectin in the regulation of type 2 diabetes, hyperlipidemia and atherosclerosisPrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  ゲノムマッピングと候補遺伝子による日本人糖尿病原因遺伝子の同定とその機能解析Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  CBPによる脂肪細胞分化・肥大化及びインスリン感受性の調節メカニズムPrincipal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  SREBP-1の制御機構の解明と抑制薬の開発

    • Principal Investigator
      戸辺 一之
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Dissection of the Mechanism of Diabetes by Genetically Engineered Animals

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  Regulation of bone and cartilage metabolism by nucleotide pyrophosphatase (NPPS) -skeletal analysis of ttw mice and its contribution to the human npps gene SNPs -

    • Principal Investigator
      NAKAGAWA Takumi, 五嶋 孝博
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  PPARγ antagonist ameliorates obesity, insulin resistance and atherosclerosis.

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  マイクロサテライトマーカーを用いた罹患同胞対法による糖尿病原因遺伝子のマッピングPrincipal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  罹患同胞対法・全ゲノムマッピングによる日本人糖尿病原因遺伝子の同定とその機能解析Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  The study for molecular mechanisms of obesity, insulin resistance and atherosclerosis in the PPAR gamma deficient micePrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Development of novel diagnostic and therapeutic strategies for obesity and insulin resistance by identification of endogenous PPARγ ligandsPrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Identification of type 2 diabetes susceptibility genes in the Japanese population by genome mapping and candidate gene approach and functional analysisPrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tokyo
  •  Mechanism of regulation of bone metabolism by insulin receptor substrates (IRS-1 and IRS-2)

    • Principal Investigator
      KONO Shinjiro, 東 成一, 小崎 慶介
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  発癌に連なるチロシンキナーゼの情報伝達系の異常とその分子機構の解明に関する研究Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  サテライトマーカーを用いた罹患同胞対法による糖尿病原因遺伝子のマッピングPrincipal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  動脈硬化発症におけるインスリン抵抗性の役割の解明

    • Principal Investigator
      戸辺 一之
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  PPARγの内因性リガンドの精製と同定

    • Principal Investigator
      戸辺 一之
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  β細胞におけるPI3キナーゼを介するシグナル伝達の病態生理学的意義の検討Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Dissection of the Mechanism of Insulin Resistance by Transgenic and knockout Mice Technology

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Metabolomics
    • Research Institution
      University of Tokyo
  •  Comprehensive Analysis of Genetic Factors in Diabetes Mellitus

    • Principal Investigator
      SEINO Susumu
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Chiba University
  •  Approach to the pathogenesis of NIDDM using knockout mouse models.Principal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Dissection of the Mechanism of Obesity-induced Insulin Resistance

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  Identification of susceptibility genes for type 2 diabetes in the Japanese using affected sib pair analysisPrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  Dissection of the Mechanism of Obesity-induced Insullin Resistance

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  Identification of NIDDM susceptibility genes in the Japanese population by candidate gene approach and whole genome mapping.Principal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  受容体チロシンキナーゼによるシグナル伝達と細胞増殖・癌化における役割とその制御Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  糖尿病および脳下垂体機能不全におけるミトコンドリア遺伝子異常とその機能解析

    • Principal Investigator
      小田原 雅人
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tsukuba
  •  日本人糖尿病の成因におけるミトコンドリT異常の役割Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  インスリン受容体基質1のインスリン作用における役割

    • Principal Investigator
      戸辺 一之
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  非インスリン依存性糖尿病におけるインスリン受容体の遺伝子変異と受容体の機能について

    • Principal Investigator
      小田原 雅人
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tsukuba
  •  インスリン非依存型糖尿病多発家系における糖代謝関連遺伝子の変異の検索Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  インスリン非依存性糖尿病の成因におけるグルコキナーゼの役割について

    • Principal Investigator
      佐倉 宏
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Generation of Animal Models for Diabetes by Transgenic and Gene Targeting TechnologyPrincipal Investigator

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  受容体型チロシンキナーゼを介する情報伝達機構

    • Principal Investigator
      春日 雅人
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  変異遺伝子を用いたインスリン受容体膜直下ドメイン及びC末端ドメインの機能解析Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  インスリン遺伝子転写制御機構に関する研究

    • Principal Investigator
      佐倉 宏
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  受容体型チロシンキナ-ゼを介する情報伝達機構

    • Principal Investigator
      KASUGA Masato
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  インスリン抵抗性糖尿病におけるインスリン受容体遺伝子変異の同定とその機能解析Principal Investigator

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  インスリン受容体キナ-ゼの活性化機構について

    • Principal Investigator
      小田原 雅人
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  細胞増殖・癌化機構におけるチロシン燐酸化標的蛋白質の同定とその生理的役割

    • Principal Investigator
      春日 雅人
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo

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    • Author(s)
      岩部 美紀、岩部 真人、山内 敏正、門脇 孝
    • Total Pages
      155
    • Publisher
      株式会社 診断と治療社
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Book] 「特別企画:Claude Bernard賞を受賞して」糖尿病学20212021

    • Author(s)
      門脇 孝
    • Total Pages
      155
    • Publisher
      株式会社 診断と治療社
    • Data Source
      KAKENHI-PROJECT-19H01052
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    • Author(s)
      門脇 孝
    • Total Pages
      96
    • Publisher
      自然科学社
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Book] 「序文」糖尿病学20212021

    • Author(s)
      門脇 孝、山内 敏正
    • Total Pages
      155
    • Publisher
      株式会社 診断と治療社
    • Data Source
      KAKENHI-PROJECT-19H01052
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    • Author(s)
      門脇 孝
    • Total Pages
      91
    • Publisher
      株式会社メテオ
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Book] PROGRESS IN MEDICINE : 【SGLT2阻害薬Update】2020

    • Author(s)
      門脇 孝
    • Pages
      7-8
    • Total Pages
      91
    • Publisher
      株式会社メテオ
    • Data Source
      KAKENHI-PROJECT-26000012
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    • Author(s)
      門脇 孝
    • Total Pages
      98
    • Publisher
      北隆館
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Book] セミナーII 糖尿病の管理・治療のドリーム 糖尿病UP・DATE 賢島セミナー 20192020

    • Author(s)
      門脇 孝
    • Total Pages
      247
    • Publisher
      メディカル・ジャーナル社
    • Data Source
      KAKENHI-PROJECT-19H01052
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    • Author(s)
      庄嶋 伸浩、山内 敏正、鈴木 顕、細江 準、門脇 孝
    • Pages
      206-213
    • Total Pages
      78
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 糖尿病UP-DATE : 【臨床研究から日常診療へのシームレスな活用】 臨床研究に学ぶ糖尿病治療の現況と展望2019

    • Author(s)
      門脇 孝
    • Pages
      102-115
    • Total Pages
      256
    • Publisher
      株式会社 メディカル・ジャーナル社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 糖尿病UP-DATE:【臨床研究から日常診療へのシームレスな活用】 臨床研究に学ぶ糖尿病治療の現況と展望2019

    • Author(s)
      門脇 孝
    • Total Pages
      256
    • Publisher
      株式会社 メディカル・ジャーナル社
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Book] 日本内科学雑誌 管理が困難な糖尿病とその対策2018

    • Author(s)
      門脇 孝、山内 敏正、鈴木 亮
    • Pages
      1810-1818
    • Total Pages
      376
    • Publisher
      日本内科学会
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 内分泌・糖尿病・代謝内科 腎臓における糖新生調節機構2018

    • Author(s)
      窪田 直人、佐々木 元大、笹子 敬洋、門脇孝
    • Pages
      310-314
    • Total Pages
      62
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 糖尿病UP・DATE 賢島セミナー2017(34) 糖尿病性合併症へのシームレスな対応 -血管合併症の早期診断と予防- 糖尿病性合併症を見据えた糖尿病の治療の今後2018

    • Author(s)
      門脇 孝
    • Pages
      98-109
    • Total Pages
      264
    • Publisher
      メディカル・ジャーナル社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 糖尿病の最新治療 : 【糖尿病の新時代-患者中心の療養指導】2025年に向けての糖尿病治療の課題と展望 日本糖尿病学会の取り組み2017

    • Author(s)
      門脇 孝
    • Pages
      4-9
    • Total Pages
      50
    • Publisher
      フジメディカル出版
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] CLININCAL CALCIUM2017

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Total Pages
      143
    • Publisher
      医薬ジャーナル社
    • ISBN
      9784753286270
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Book] 日本医師会雑誌 : 臨床医のための食事療法のポイント(No.47) 健康寿命延伸にむけた、肥満、糖尿病の予防・重症化予防 日本型食生活の役割 糖尿病の成因とその予防、治療のための健康的な食事と運動の勧め(図説)2017

    • Author(s)
      門脇 孝
    • Total Pages
      220
    • Publisher
      日本医師会
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] Islet Equality : 『Islet Equality』創刊5年を振り返る 膵島研究の変遷(座談会)2017

    • Author(s)
      門脇 孝、荒木 栄一、石原 寿光、稲垣 暢也、寺内 康夫
    • Pages
      5-14
    • Total Pages
      32
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 実験医学増刊 : 【糖尿病研究の“いま”と治療の“これから”】インスリン抵抗性はなぜ起きるのか? Overview インスリン作用の基本メカニズムと最新の研究動向(解説/特集)2017

    • Author(s)
      門脇 孝
    • Pages
      190-200
    • Total Pages
      236
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] ここがポイント! 見てわかる高齢者の糖尿病2017

    • Author(s)
      門脇 孝
    • Total Pages
      79
    • Publisher
      メディカ出版
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 動脈・静脈の疾患(下)日本臨床2017

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Total Pages
      610
    • Publisher
      日本臨牀社
    • ISBN
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Book] 糖尿病UP-DATE : 【病状・病態に応じたシームレスな管理・治療-病型と合併症併発に応じた適切な対応】病態に応じた経口血糖降下剤による治療 2型糖尿病の病態と経口血糖降下剤そしてそれを用いた治療の進歩(解説/特集)2017

    • Author(s)
      門脇 孝
    • Pages
      102-110
    • Total Pages
      248
    • Publisher
      メディカル・ジャーナル社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 実験医学増刊 糖尿病 研究の“いま”と治療の“これから” : Overview インスリン作用の基本メカニズムと最新の研究動向2017

    • Author(s)
      門脇 孝
    • Pages
      194-200
    • Total Pages
      236
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 糖尿病学20172017

    • Author(s)
      門脇 孝
    • Total Pages
      184
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] Diabetes Journal : 糖尿病と代謝 : メトホルミンおよびSGLT2阻害薬の適正使用に関する Recommendation(解説)2017

    • Author(s)
      門脇 孝
    • Pages
      18-21
    • Total Pages
      31
    • Publisher
      ディアベテス・ジャーナル社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 糖尿病【肥満糖尿病克服への新たな挑戦】「 アディポロンと健康長寿」2016

    • Author(s)
      岩部 美紀、山内 敏正、門脇 孝
    • Total Pages
      50
    • Publisher
      一般社団法人日本糖尿病学会
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Book] 内分泌・糖尿病・代謝内科【話題】「アディポロン」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Total Pages
      82
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Book] 実験医学・【「解明」から「制御」へ 肥満症のメディカルサイエンス】 (第1章)エネルギー代謝の制御機構 「アディポネクチンの生理機能 ー肥満・2型糖尿病治療に向けて」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Total Pages
      212
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Book] Progress in Medicine : 【SGLT2阻害薬を再評価するー明らかになってきた効果と副作用ー】 SGLT2阻害薬への今後の期待2016

    • Author(s)
      門脇 孝、窪田 直人
    • Total Pages
      154
    • Publisher
      (株)ライフ・サイエンス
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 内分泌・糖尿病・代謝内科「アディポネクチン受容体の構造」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Total Pages
      90
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Book] 糖尿病【肥満糖尿病克服への新たな挑戦】「 アディポロンと健康長寿」2016

    • Author(s)
      岩部 美紀、山内 敏正、門脇 孝
    • Total Pages
      50
    • Publisher
      一般社団法人日本糖尿病学会
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Book] Medical Science Digest2016

    • Author(s)
      窪田直人、門脇孝
    • Total Pages
      4
    • Publisher
      ニュー・サイエンス社
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Book] Medical Science Digest : 総論「腎と糖・エネルギー代謝」特集にあたって2016

    • Author(s)
      門脇 孝
    • Pages
      5-6
    • Total Pages
      46
    • Publisher
      北隆館・ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 医学のすすめ : すべては患者の幸せと医療の発展のために2016

    • Author(s)
      門脇 孝
    • Pages
      1-219
    • Total Pages
      219
    • Publisher
      西村書店
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 日本内科学雑誌 : 2型糖尿病の成因解明と治療戦略 30年の歩み2016

    • Author(s)
      門脇 孝
    • Pages
      1543-1557
    • Total Pages
      386
    • Publisher
      日本内科学会
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 内分泌・糖尿病・代謝内科【話題】「アディポロン」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Total Pages
      82
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Book] 【薬物療法アップデート】糖吸収・排泄調節系 α-グルコシダーゼ阻害薬・SGLT2阻害薬。最新醫學別冊 診断と治療のABC 糖尿病2016

    • Author(s)
      窪田直人、門脇孝
    • Total Pages
      7
    • Publisher
      最新医学社
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Book] 内分泌・糖尿病・代謝内科「アディポネクチン受容体の構造」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Total Pages
      90
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Book] Diabetes Frontier2016

    • Author(s)
      山内 敏正、岩部 真人、細江 隼、門脇 孝
    • Total Pages
      134
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-26253058
  • [Book] 日本臨牀・『新時代の臨床糖尿病学(上)』【VII糖尿病治療 薬物療法 新規糖尿病治療薬】「アディポネクチン受容体アゴニスト(アディポロン)」2015

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Total Pages
      671
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Book] 日本臨床 : 【新時代の臨床糖尿病学(上)-より良い血糖管理をめざして-】 糖尿病疾患概念および診断基準の変遷2015

    • Author(s)
      門脇 孝
    • Total Pages
      671
    • Publisher
      (株)日本臨牀社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 血管医学・【臓器の記憶と血管代謝ニッシェ】 「アディポネクチン受容体機能低下に伴う臓器記憶の変容」2015

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Total Pages
      118
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Book] 糖尿病合併症 : 2型糖尿病とその合併症の分子基盤に関する研究2015

    • Author(s)
      門脇 孝
    • Total Pages
      246
    • Publisher
      (株)メディカル・ジャーナル社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] Islet Equality : 肥満での膵β細胞量の調整能とその機序、2型糖尿病の発症予防研究の現状と展望 肥満における膵β細胞障害と2型糖尿病2015

    • Author(s)
      門脇 孝、荒木 栄一、税所 芳史、綿田 裕孝
    • Total Pages
      671
    • Publisher
      (株)メディカル・ジャーナル社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 日本医事新報 : 2型糖尿病の分子機構と治療戦略2015

    • Author(s)
      門脇 孝
    • Total Pages
      88
    • Publisher
      (株)日本医事新報社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 【診断から治療へのシームレスなフォロー・アップ-診断と病状把握のマーカーとその活用-】 2型糖尿病とその治療の進歩 2型糖尿病およびIGTへの対応2015

    • Author(s)
      門脇 孝
    • Total Pages
      42
    • Publisher
      (株)メディカル・ジャーナル社
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] DIABETES UPDATE2014

    • Author(s)
      山内 敏正、岩部 美紀、岩部 真人、門脇 孝
    • Total Pages
      3
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-26253058
  • [Book] Diabetes Journal : 糖尿病と代謝SGLT2阻害薬の適正使用に関するRecommendation2014

    • Author(s)
      門脇孝
    • Total Pages
      199
    • Publisher
      (株)協和企画
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] Diabetes Horizons : Practice and Progress 2型糖尿病の治療におけるSGLT2阻害薬の適正使用について2014

    • Author(s)
      門脇孝、RazItamar、麻生好正
    • Total Pages
      188
    • Publisher
      (株)メディカルレビュー社
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 医学のあゆみ2014

    • Author(s)
      山内 敏正、門脇 孝
    • Total Pages
      6
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-26253058
  • [Book] 糖尿病合併症 2型糖尿病とその合併症の分子基盤に関する研究2014

    • Author(s)
      門脇孝
    • Total Pages
      455
    • Publisher
      日本糖尿病合併症学会
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] Cardio-Renal Diabetes糖尿病性大血管障害Controversyメタボリックシンドロームを伴う糖尿病の治療2014

    • Author(s)
      門脇孝、大澤春彦、綿田裕孝
    • Total Pages
      236
    • Publisher
      (株)メディカルレビュー社
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] BIO Clinica【糖尿病・メタボリックシンドローム-分子機序と治療戦略-】総論2014

    • Author(s)
      門脇孝
    • Total Pages
      1442
    • Publisher
      (株)北隆館
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 細胞【糖尿病治療の進歩】 AdipoRを標的とした健康長寿薬開発への挑戦2014

    • Author(s)
      岩部 美紀、山内 敏正、門脇 孝
    • Total Pages
      52
    • Publisher
      ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Book] Islet Equality 膵β細胞の再生医療と糖尿病治療への応用2014

    • Author(s)
      門脇孝、川口義弥、粂昭苑、宮島篤
    • Total Pages
      162
    • Publisher
      (株)メディカルレビュー社
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] Cardio-Renal Diabetes J-DOIT3からみた糖尿病の包括的治療2014

    • Author(s)
      門脇孝、植木浩二郎、羽田勝計、横手幸太郎
    • Total Pages
      236
    • Publisher
      (株)メディカルレビュー社
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] Diabetes Journal2014

    • Author(s)
      山内 敏正、門脇 孝
    • Total Pages
      9
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-26253058
  • [Book] Islet Equality2014

    • Author(s)
      門脇 孝、川口 義弥、粂 昭苑、宮島 篤
    • Total Pages
      10
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Book] 糖尿病UP-DATE【エビデンスにみる糖尿病対策のイノベーションよりよい診療を目指したベンチマーク】薬物療法の選択はいかにあるべきか エビデンスに基づく病状に応じた薬剤選択とそのすすめ方2014

    • Author(s)
      門脇孝
    • Total Pages
      296
    • Publisher
      時事通信出版局
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Book] 動脈硬化予防2014

    • Author(s)
      山内 敏正、門脇 孝
    • Total Pages
      8
    • Publisher
      メジカルビュー社
    • Data Source
      KAKENHI-PROJECT-26253058
  • [Book] 【糖尿病をめぐる話題と治療の現況】 糖尿病の分類と診断基準2013

    • Author(s)
      門脇 孝
    • Total Pages
      9
    • Publisher
      医学と薬学
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Book] Islet Equality2013

    • Author(s)
      門脇 孝
    • Total Pages
      4
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-25253068
  • [Book] 【糖尿病療養のイノベーション 生活習慣病としての糖尿病】 病態に応じた糖尿病治療 糖尿病治療の現状と展望2013

    • Author(s)
      門脇 孝
    • Total Pages
      18
    • Publisher
      糖尿病UP-DATE
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Book] Diabetes Horizons: Practice and Progress2013

    • Author(s)
      門脇 孝
    • Total Pages
      13
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-25253068
  • [Book] 医療技術・機器のイノベーションと医療の質の向上2013

    • Author(s)
      門脇 孝
    • Total Pages
      11
    • Publisher
      医療機器学
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Book] HbA1c国際標準化-日常臨床での運用の実際と啓発の重要性2012

    • Author(s)
      門脇 孝
    • Total Pages
      13
    • Publisher
      Diabetes Journal
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Book] 最新臨床糖尿病学上-糖尿病学の最新動向- I.総論 日本糖尿病学会のアクションプラン2010(DREAMS)2012

    • Author(s)
      門脇 孝
    • Total Pages
      9
    • Publisher
      日本臨牀
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Book] 最新臨床糖尿病学上-糖尿病学の最新動向- IV.糖尿病の疾患概念・病型分類・成因 2型糖尿病 2型糖尿病の疾患概念2012

    • Author(s)
      門脇 孝
    • Total Pages
      8
    • Publisher
      日本臨牀
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Book] 実験医学2011

    • Author(s)
      植木浩二郎、門脇孝
    • Data Source
      KAKENHI-PROJECT-21390278
  • [Book] 実験医学2010

    • Author(s)
      植木浩二郎,門脇孝
    • Data Source
      KAKENHI-PROJECT-21390278
  • [Book] あなたがメタボになる理由(単行本)2008

    • Author(s)
      門脇孝
    • Publisher
      PHP研究所
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Book] アディポネクチンとその受容体-抗生活習慣病ホルモンの全貌(単行本)2008

    • Author(s)
      門脇孝
    • Publisher
      フジメディカル出版
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Book] アディポネクチンの臨床応用の現状・展望(Q&A)2007

    • Author(s)
      山内 敏正、門脇 孝
    • Publisher
      日本医事新報
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Book] 【メタボリックシンドロームup to date】検査・診断アディポネクチン2007

    • Author(s)
      山内 敏正、原一 雄、門脇 孝
    • Publisher
      日本医師会雑誌
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Book] 特集糖尿病の新しい治療戦略インスリン抵抗性改善薬の現状と未来2007

    • Author(s)
      山内 敏正、門脇 孝
    • Publisher
      最新医学社
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Book] 【糖尿病の新しい治療戦略】糖尿病の治療戦略インスリン抵抗性改善薬の現状と未来2007

    • Author(s)
      山内 敏正、門脇 孝
    • Publisher
      最新医学
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Book] 【糖尿病による心血管合併症】インスリン抵抗性と動脈硬化症2007

    • Author(s)
      山内 敏正、門脇 孝
    • Publisher
      BIO Clinica
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Book] 脂質代議常-高脂血症・低脂血症-I概論高脂血症と動脈硬化動脈硬化発症にかかわるアディポサイトカインの役割2007

    • Author(s)
      山内 敏正、門脇 孝
    • Publisher
      日本臨牀
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Book] オスモチン2007

    • Author(s)
      山内 敏正、門脇 孝
    • Publisher
      臨床栄養
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Book] アディポサイトカイン調節を改善する食事療法2007

    • Author(s)
      山内 敏正、門脇 孝
    • Publisher
      Adiposcience
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Elucidating exercise-induced skeletal muscle signaling pathways and applying relevant findings to preemptive therapy for lifestyle-related diseases2022

    • Author(s)
      Iwabu Masato、Okada-Iwabu Miki、Kadowaki Takashi、Yamauchi Toshimasa
    • Journal Title

      Endocr J

      Volume: 69 Issue: 1 Pages: 1-8

    • DOI

      10.1507/endocrj.EJ21-0294

    • NAID

      130008145270

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-19H01052
  • [Journal Article] Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone?Releasing Hormone in the Hypothalamus2021

    • Author(s)
      Hayashi Takanori、Kubota Tetsuya、Mariko Inoue、Takamoto Iseki、Aihara Masakazu、Sakurai Yoshitaka、Wada Nobuhiro、Miki Takashi、Yamauchi Toshimasa、Kubota Naoto、Kadowaki Takashi
    • Journal Title

      Diabetes

      Volume: 70 Issue: 8 Pages: 1640-1653

    • DOI

      10.2337/db20-0482

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07281, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17977, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-21K19496
  • [Journal Article] Preparation and culture of bone marrow-derived macrophages from mice for functional analysis.2021

    • Author(s)
      Gotaro Toda, Toshimasa Yamauchi, Takashi Kadowaki, and Kohjiro Ueki
    • Journal Title

      STAR Protocols

      Volume: 2 Issue: 1 Pages: 100246-100246

    • DOI

      10.1016/j.xpro.2020.100246

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17954, KAKENHI-PROJECT-19H01052
  • [Journal Article] Midlobular zone 2 hepatocytes: A gatekeeper of liver homeostasis2021

    • Author(s)
      Kubota Naoto、Kubota Tetsuya、Kadowaki Takashi
    • Journal Title

      Cell Metabolism

      Volume: 33 Issue: 5 Pages: 855-856

    • DOI

      10.1016/j.cmet.2021.04.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19H01052
  • [Journal Article] AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice2021

    • Author(s)
      Iwabu Masato、Okada-Iwabu Miki、Tanabe Hiroaki、Ohuchi Nozomi、Miyata Keiko、Kobori Toshiko、Odawara Sara、Kadowaki Yuri、Yokoyama Shigeyuki、Yamauchi Toshimasa、Kadowaki Takashi
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 45-45

    • DOI

      10.1038/s42003-020-01579-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-18K10988
  • [Journal Article] Human adiponectin receptor AdipoR1 assumes closed and open structures2020

    • Author(s)
      Tanabe Hiroaki、Fujii Yoshifumi、Okada-Iwabu Miki、Iwabu Masato、Kano Kuniyuki、Kawana Hiroki、Hato Masakatsu、Nakamura Yoshihiro、Terada Takaho、Kimura-Someya Tomomi、Shirouzu Mikako、Kawano Yoshiaki、Yamamoto Masaki、Aoki Junken、Yamauchi Toshimasa、Kadowaki Takashi、Yokoyama Shigeyuki
    • Journal Title

      Communications Biology

      Volume: 3 Issue: 1 Pages: 446-446

    • DOI

      10.1038/s42003-020-01160-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-18K10988
  • [Journal Article] NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation2020

    • Author(s)
      Hiraike Yuta、Waki Hironori、Miyake Kana、Wada Takahito、Oguchi Misato、Saito Kaede、Tsutsumi Shuichi、Aburatani Hiroyuki、Yamauchi Toshimasa、Kadowaki Takashi
    • Journal Title

      PLOS Genetics

      Volume: 16 Issue: 9 Pages: e1009044-e1009044

    • DOI

      10.1371/journal.pgen.1009044

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-20H04101
  • [Journal Article] Blood Glucose Control Strategy for Type 2 Diabetes Patients With COVID-192020

    • Author(s)
      Futatsugi Hiroyuki、Iwabu Masato、Okada-Iwabu Miki、Okamoto Koh、Amano Yosuke、Morizaki Yutaka、Kadowaki Takashi、Yamauchi Toshimasa
    • Journal Title

      Frontiers in Cardiovascular Medicine

      Volume: 7 Pages: 593061-593061

    • DOI

      10.3389/fcvm.2020.593061

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-19H01052
  • [Journal Article] Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice2020

    • Author(s)
      Mai Sugahara、Shinji Tanaka、Tetsuhiro Tanaka、Hisako Saito、Yu Ishimoto、Takeshi Wakashima、Masatoshi Ueda、Kenji Fukui、Akira Shimizu、Reiko Inagi、Toshimasa Yamauchi、Takashi Kadowaki、Masaomi Nangaku
    • Journal Title

      Journal of the American Society of Nephrology

      Volume: 31 Issue: 3 Pages: 560-577

    • DOI

      10.1681/asn.2019060582

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17731, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824
  • [Journal Article] Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation2020

    • Author(s)
      Toda G、Soeda K、Okazaki Y、Kobayashi N、Masuda Y、Arakawa N、Suwanai H、Masamoto Y、Izumida Y、Kamei N、Sasako T、Suzuki R、Kubota T、Kubota N、Kurokawa M、Tobe K、Noda T、Honda K、Accili D、Yamauchi T、Kadowaki T、Ueki K
    • Journal Title

      Molecular Cell

      Volume: 79 Issue: 1 Pages: 1-2

    • DOI

      10.1016/j.molcel.2020.04.033

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07898, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17954, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K00846, KAKENHI-PROJECT-18K15075
  • [Journal Article] Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34+ cells using the auto-erasable Sendai virus vector.2019

    • Author(s)
      Okumura T, Horie Y, et al.
    • Journal Title

      Stem Cell Res Ther.

      Volume: 10 Issue: 1 Pages: 185-185

    • DOI

      10.1186/s13287-019-1273-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08246, KAKENHI-PROJECT-18K16141, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K09971, KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-17K19600, KAKENHI-PROJECT-26000012
  • [Journal Article] Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.2019

    • Author(s)
      Suzuki K, Akiyama M, Ishigaki K, Kanai M, Hosoe J, Shojima N, Hozawa A, Kadota A, Kuriki K, Naito M, Tanno K, Ishigaki Y, et al.
    • Journal Title

      Nat Genet.

      Volume: 51 Issue: 3 Pages: 379-386

    • DOI

      10.1038/s41588-018-0332-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08523, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-16H05378, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-17H04251, KAKENHI-PROJECT-26000012
  • [Journal Article] Adiponectin/AdipoR Research and Its Implications for Lifestyle-Related Diseases2019

    • Author(s)
      Iwabu Masato、Okada-Iwabu Miki、Yamauchi Toshimasa、Kadowaki Takashi
    • Journal Title

      Frontiers in Cardiovascular Medicine

      Volume: 6 Pages: 116-116

    • DOI

      10.3389/fcvm.2019.00116

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10988, KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-26000012
  • [Journal Article] Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency2019

    • Author(s)
      Takanashi M, Kimura T, Li C, Tanaka M, Matsuhashi A, Yoshida H, Noda A, Xu P, Takase S, Okazaki S, Iizuka Y, Kumagai H, Ikeda Y, Gotoda T, Takahashi M, Yagyu H, Ishibashi S, Yamauchi T, Kadowaki T, Liang G, Okazaki H.
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology

      Volume: 39 Issue: 3 Pages: 373-386

    • DOI

      10.1161/atvbaha.118.311931

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08585, KAKENHI-PROJECT-17K09858, KAKENHI-PROJECT-18K08504, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-17K09867, KAKENHI-PROJECT-26000012
  • [Journal Article] Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease2019

    • Author(s)
      Tomoko Wakabayashi, Kazuki Yamaguchi, Kentaro Matsui, Toshiharu Sano, Tetsuya Kubota, Tadafumi Hashimoto, Ayako Mano, Kaoru Yamada, Yuko Matsuo, Naoto Kubota, Takashi Kadowaki, Takeshi Iwatsubo
    • Journal Title

      Molecular Neurodegeneration

      Volume: 14 Issue: 1 Pages: 15-15

    • DOI

      10.1186/s13024-019-0315-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07364, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-17H04193, KAKENHI-PROJECT-18H02860
  • [Journal Article] Drug development research for novel adiponectin receptor-targeted antidiabetic drugs contributing to healthy longevity2019

    • Author(s)
      Okada-Iwabu Miki、Iwabu Masato、Yamauchi Toshimasa、Kadowaki Takashi
    • Journal Title

      DIABETOLOGY INTERNATIONAL

      Volume: 10 Issue: 4 Pages: 237-244

    • DOI

      10.1007/s13340-019-00409-6

    • NAID

      40022039924

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10988, KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-26000012
  • [Journal Article] NAD + supplementation rejuvenates aged gut adult stem cells2019

    • Author(s)
      Igarashi M*, Miura M, Williams E, Jaksch F, Kadowaki T, Yamauchi T* , Guarente L
    • Journal Title

      Aging Cell

      Volume: - Issue: 3 Pages: 1-10

    • DOI

      10.1111/acel.12935

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-17H06631, KAKENHI-PROJECT-19K09017, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-26000012
  • [Journal Article] Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism2019

    • Author(s)
      Sasako T., Ohsugi M., Kubota N., Itoh S., Okazaki Y, Terai A., Kubota T., Yamashita S., Nakatsukasa K., Kamura T., Iwayama K., Tokuyama K., Kiyonari H., Furuta Y., Shibahara J., Fukayama M., Enooku K., Okushin K., Tsutsumi T., Tateishi R., Tobe K., Asahara H., Koike K., *Kadowaki T. & *Ueki K.
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 1-16

    • DOI

      10.1038/s41467-019-08591-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-17H03652, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-18H02860
  • [Journal Article] Pivotal role of inter-organ aspartate metabolism for treatment of mitochondrial aspartate-glutamate carrier 2 (citrin) deficiency, based on the mouse model.2019

    • Author(s)
      Saheki T, Moriyama M, Kuroda E, Funahashi A, Yasuda I, Setogawa Y, Gao Q, Ushikai M, Furuie S, Yamamura KI, Takano K, Nakamura Y, Eto K, Kadowaki T, Sinasac DS, Furukawa T, Horiuchi M, Tai YH.
    • Journal Title

      Sci Rep. 2019 Mar 12;9(1):4179.

      Volume: 9 (1) Issue: 1 Pages: 4179-4179

    • DOI

      10.1038/s41598-019-39627-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05999, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-26000012
  • [Journal Article] Structure and function analysis of adiponectin receptors toward development of novel antidiabetic agents promoting healthy longevity2018

    • Author(s)
      Okada-Iwabu Miki、Iwabu Masato、Yamauchi Toshimasa、Kadowaki Takashi
    • Journal Title

      Endocr J

      Volume: 65 Issue: 10 Pages: 971-977

    • DOI

      10.1507/endocrj.EJ18-0310

    • NAID

      130007501453

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10988, KAKENHI-PROJECT-26000012
  • [Journal Article] Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity2018

    • Author(s)
      Kubota Tetsuya、Inoue Mariko、Kubota Naoto、Takamoto Iseki、Mineyama Tomoka、Iwayama Kaito、Tokuyama Kumpei、Moroi Masao、Ueki Kohjiro、Yamauchi Toshimasa、Kadowaki Takashi
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 4863-4863

    • DOI

      10.1038/s41467-018-07358-9

    • NAID

      120007133395

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19556, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-26000012
  • [Journal Article] The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.2018

    • Author(s)
      Kobayashi M, Ohsugi M, Sasako T, Awazawa M, Umehara T, Iwane A, Kobayashi N, Okazaki Y, Kubota N, Suzuki R, Waki H, Horiuchi K, Hamakubo T, Kodama T, Aoe S, Tobe K, Kadowaki T, Ueki K
    • Journal Title

      Mol. Cell Biol.

      Volume: 38 Issue: 16 Pages: 81-91

    • DOI

      10.1128/mcb.00116-18

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19556, KAKENHI-PROJECT-18K15075, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-16K09776, KAKENHI-PROJECT-17K09819, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-18H02860
  • [Journal Article] NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program.2017

    • Author(s)
      Hiraike Y, Waki H, Yu J, Nakamura M, Miyake K, Nagano G, Nakaki R, Suzuki K, Kobayashi H, Yamamoto S, Sun W, Aoyama T, Hirota Y, Ohno H, Oki K, Yoneda M, White AP, Tseng YH, Cypess AM, Larsen TJ, Jespersen NZ, Scheele C, Tsutsumi S, Aburatani H, Yamauchi T, Kadowaki T
    • Journal Title

      Nature cell biology

      Volume: 19(9) Issue: 9 Pages: 1081-1092

    • DOI

      10.1038/ncb3590

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09818, KAKENHI-PROJECT-17K09883, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-26000012
  • [Journal Article] Adiponectin at physiological level glucose-independently enhances inhibitory postsynaptic current onto NPY neurons in the hypothalamic arcuate nucleus2017

    • Author(s)
      Suyama Shigetomo、Lei Wang、Kubota Naoto、Kadowaki Takashi、Yada Toshihiko
    • Journal Title

      Neuropeptides

      Volume: 65 Pages: 1-9

    • DOI

      10.1016/j.npep.2017.03.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Journal Article] Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials.2017

    • Author(s)
      Yamada T, Shojima N, Noma H, Yamauchi T, Kadowaki T.
    • Journal Title

      Intensive Care Medicine

      Volume: 43 Issue: 1 Pages: 1-15

    • DOI

      10.1007/s00134-016-4523-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09409, KAKENHI-PROJECT-16K20965, KAKENHI-PROJECT-26000012
  • [Journal Article] Role of insulin receptor substrates in the progression of hepatocellular carcinoma2017

    • Author(s)
      Sakurai Yoshitaka、Kubota Naoto、Takamoto Iseki、Obata Atsushi、Iwamoto Masahiko、Hayashi Takanori、Aihara Masakazu、Kubota Tetsuya、Nishihara Hiroshi、Kadowaki Takashi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 5387-5387

    • DOI

      10.1038/s41598-017-03299-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15612, KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-26000012
  • [Journal Article] CDK5 Regulatory Subunit-Associated Protein l-like I Negatively Regulates Adipocyte Differentiation through Activation of Wnt Signaling Pathway.2017

    • Author(s)
      Take K, Waki H, Sun W, Wada T, Yu J, Nakamura M, Aoyama T, Yamauchi T, Kadowaki T
    • Journal Title

      Sci Rep.

      Volume: 7 Issue: 1 Pages: 7326-7326

    • DOI

      10.1038/s41598-017-06469-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] New glysemic targets for patients with diabetes from the Japan Diabetes Society2017

    • Author(s)
      Araki E, Haneda M, Kasuga M, Nishikawa T, Kondo T, Ueki K, Kadowaki T
    • Journal Title

      J Diabetes Investig

      Volume: 8 Issue: 1 Pages: 123-125

    • DOI

      10.1111/jdi.12600

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15348, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-15K09394
  • [Journal Article] Novel and Simple Ultrasonographic Methods for Estimating the Abdominal Visceral Fat Area2017

    • Author(s)
      Asano Takeharu、Kubota Naoto、Koizumi Norihiro、Itani Kazunori、Mitake Tsuyoshi、Yuhashi Kazuhito、Liao Hongen、Mitsuishi Mamoru、Takeishi Shigemi、Takahashi Toshiaki、Ohnishi Shin、Sasaki Shiro、Sakuma Ichiro、Kadowaki Takashi
    • Journal Title

      Int J Endocrinol.

      Volume: 2017 Pages: 1-12

    • DOI

      10.1155/2017/8796069

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-17H03200
  • [Journal Article] Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney2017

    • Author(s)
      Sasaki Motohiro、Sasako Takayoshi、Kubota Naoto、Sakurai Yoshitaka、Takamoto Iseki、Kubota Tetsuya、Inagi Reiko、Seki George、Goto Moritaka、Ueki Kohjiro、Nangaku Masaomi、Jomori Takahito、Kadowaki Takashi
    • Journal Title

      Diabetes

      Volume: 66 Issue: 9 Pages: 2339-2350

    • DOI

      10.2337/db16-1602

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15612, KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465, KAKENHI-PROJECT-26000012
  • [Journal Article] Imbalanced Insulin Actions in Obesity and Type 2 Diabetes: Key Mouse Models of Insulin Signaling Pathway2017

    • Author(s)
      Kubota Tetsuya、Kubota Naoto、Kadowaki Takashi
    • Journal Title

      Cell Metab.

      Volume: 25 Issue: 4 Pages: 797-810

    • DOI

      10.1016/j.cmet.2017.03.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-26000012
  • [Journal Article] J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis.2016

    • Author(s)
      Yamada T, Shojima N, Yamauchi T, Kadowaki T
    • Journal Title

      Scientific Report

      Volume: 6 Issue: 1 Pages: 38075-38075

    • DOI

      10.1038/srep38075

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09409, KAKENHI-PROJECT-16K20965, KAKENHI-PROJECT-26000012
  • [Journal Article] Adiponectin enhances antibacterial activity of hematopoietic cells by suppressing bone marrow inflammation.2016

    • Author(s)
      Masamoto Y, Arai S, Sato T, Yoshimi A, Kubota N, Takamoto I, Iwakura Y, Yoshimura A, Kadowaki T, Kurokawa M
    • Journal Title

      Immunity

      Volume: 44 Issue: 6 Pages: 1422-33

    • DOI

      10.1016/j.immuni.2016.05.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01481, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-25221305, KAKENHI-PROJECT-16K15500, KAKENHI-PROJECT-26000012
  • [Journal Article] Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice2016

    • Author(s)
      Obata A, Kubota N, Kubota T, Iwamoto M, Sato H, Sakurai Y, Takamoto I, Katsuyama H, Suzuki Y, Fukazawa M, Ikeda S, Iwayama K, Tokuyama K, Ueki K and Kadowaki T
    • Journal Title

      Endocrinology

      Volume: 157 Issue: 3 Pages: 1029-1042

    • DOI

      10.1210/en.2015-1588

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-14J03079, KAKENHI-PROJECT-26000012
  • [Journal Article] Genes associated with diabetes : potential for novel therapeutic targets?2016

    • Author(s)
      Hara K, Kadowaki T, Odawara M.
    • Journal Title

      Expert Opin. Ther. Targets

      Volume: 20 Issue: 3 Pages: 255-267

    • DOI

      10.1517/14728222.2016.1098618

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Lactic acidosis due to attempted suicide with metformin overdose: A case report.2016

    • Author(s)
      Yamada T, Shojima N, Yamauchi T, Kadowaki T.
    • Journal Title

      Diabetes Metabolism

      Volume: 42 Issue: 4 Pages: 290-291

    • DOI

      10.1016/j.diabet.2016.03.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09409, KAKENHI-PROJECT-26000012
  • [Journal Article] Anagliptin increases insulin-induced skeletal muscle glucose uptake via an NO-dependent mechanism in mice.2016

    • Author(s)
      Sato H, Kubota N, Kubota T, Takamoto I, Iwayama K, Tokuyama K, Moroi M, Sugi K, Nakaya K, Goto M, Jomori T, Kadowaki T.
    • Journal Title

      Diabetologia

      Volume: 59 Issue: 11 Pages: 2426-2434

    • DOI

      10.1007/s00125-016-4071-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-26000012
  • [Journal Article] Glucose level determines excitatory or inhibitory effects of adiponectin on arcuate POMC neuron activity and feeding.2016

    • Author(s)
      Suyama S, Maekawa F, Maejima Y, Kubota N, Kadowaki T, Yada T
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 30796-30796

    • DOI

      10.1038/srep30796

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15182, KAKENHI-PROJECT-26000012
  • [Journal Article] Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.2016

    • Author(s)
      Imamura M, ・・Yamauchi T,・・ Shojima N, ・・Kadowaki T
    • Journal Title

      Nat Commun.

      Volume: 7 Issue: 1 Pages: 10531-10531

    • DOI

      10.1038/ncomms10531

    • NAID

      120006889946

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09409, KAKENHI-PUBLICLY-15H01507, KAKENHI-PLANNED-15H05911, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-15H05670, KAKENHI-PROJECT-26461327, KAKENHI-PROJECT-26000012
  • [Journal Article] Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity.2016

    • Author(s)
      Kubota N, Kubota T, Kajiwara E, Iwamura T, Kumagai H, Watanabe T, Inoue M, Takamoto I, Sasako T, Kumagai K, Kohjima M, Nakamuta M, Moroi M, Sugi K, Noda T, Terauchi Y, Ueki K, Kadowaki T.
    • Journal Title

      Nat Commun.

      Volume: 7 Issue: 1 Pages: 12977-12977

    • DOI

      10.1038/ncomms12977

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-16H05329, KAKENHI-PROJECT-16K15488, KAKENHI-PROJECT-26000012
  • [Journal Article] Pioglitazone Ameliorates Smooth Muscle Cell Proliferation in Cuff-Induced Neointimal Formation by Both Adiponectin-Dependent and -Independent Pathways.2016

    • Author(s)
      Kubota T, Kubota N, Sato H, Inoue M, Kumagai H, Iwamura T, Takamoto I, Kobayashi T, Moroi M, Terauchi Y, Tobe K, Ueki K, Kadowaki T
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 34707-34707

    • DOI

      10.1038/srep34707

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-16H05329, KAKENHI-PROJECT-26461327, KAKENHI-PROJECT-15K07975, KAKENHI-PROJECT-26000012
  • [Journal Article] Adiponectin/adiponectin receptor in disease and aging.2015

    • Author(s)
      Iwabu M, Okada-Iwabu M, Yamauchi T, Kadowaki T
    • Journal Title

      npj Aging and Mechanisms of Disease

      Volume: 1 Issue: 1 Pages: 15013-15013

    • DOI

      10.1038/npjamd.2015.13

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
  • [Journal Article] Mechanism for increased hepatic glycerol synthesis in the citrin/mitochondria glycerol-3-phosphate dehydrogenase double-knockout mouse: Urine glycerol and glycerol 3-phosphate as potential diagnostic markers of human citrin deficiency.2015

    • Author(s)
      Moriyama M, Fujimoto Y, Rikimaru S,Ushikai M, Kuroda E, Kawabe K, Takano K,Asakawa A, Inui A, Eto K, Kadowaki T, Sinasac DS, Okano Y, Yazaki M, Ikeda SI,Zhang C, Song YZ,Sakamoto O, Kure S, Mitsubuchi H, Endo F, Horiuchi M, Nakamura Y, Yamamura KI, Saheki T.
    • Journal Title

      Biochim Biophys Acta.

      Volume: 印刷中 Issue: 9 Pages: 1787-1795

    • DOI

      10.1016/j.bbadis.2015.04.023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590892, KAKENHI-PROJECT-15K07768, KAKENHI-PROJECT-15K09595, KAKENHI-PROJECT-26450447, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15J12259, KAKENHI-PROJECT-25461275, KAKENHI-PROJECT-26850209, KAKENHI-PROJECT-26000012
  • [Journal Article] Insulin Receptor Substrate-2 (Irs2) in Endothelial Cells Plays a Crucial Role in Insulin Secretion.2015

    • Author(s)
      ・Hashimoto S, Kubota N, Sato H, Sasaki M, Takamoto I, Kubota T, Nakaya K, Noda M, Ueki K, Kadowaki T
    • Journal Title

      Diabetes

      Volume: 64 Pages: 876-886

    • NAID

      40020753201

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Journal Article] L-cysteine reversibly inhibits glucose-induced biphasic insulin secretion and ATP production by inactivating PKM22015

    • Author(s)
      Nakatsu, D., Horiuchi, Y., Kano, F., Noguchi, Y., Sugawara, T., Takamoto, I., Kubota, N., Kadowaki, T., Murata, M.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: - Issue: 10

    • DOI

      10.1073/pnas.1417197112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01631, KAKENHI-PROJECT-26000012
  • [Journal Article] A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese2015

    • Author(s)
      Hirokawa, M., Morita H., Tajima T., Takahashi A., Ashikawa K., Miya F., Shigemizu D., Ozaki K., Sakata Y., Nakatani D., Suna S., Imai Y., Tanaka T., Tsunoda T., Matsuda K., Kadowaki T., Nakamura Y., Nagai R., Komuro I. and Kubo M.
    • Journal Title

      Eur J Hum Genet

      Volume: 23 Issue: 3 Pages: 374-380

    • DOI

      10.1038/ejhg.2014.110

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26000012
  • [Journal Article] Daytime Napping and the Risk of Cardiovascular Disease and All-Cause Mortality: A Prospective Study and Dose-Response Meta-Analysis.2015

    • Author(s)
      Yamada T, Hara K, Shojima N, Yamauchi T, Kadowaki T
    • Journal Title

      Sleep

      Volume: 38 Issue: 12 Pages: 1945-1953

    • DOI

      10.5665/sleep.5246

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09409, KAKENHI-PUBLICLY-15H01507, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26000012
  • [Journal Article] Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity2015

    • Author(s)
      Okada-Iwabu M, Iwabu M, Ueki K, Yamauchi T and Kadowaki T.
    • Journal Title

      Diabetes Metab J

      Volume: 39 Issue: 5 Pages: 363-372

    • DOI

      10.4093/dmj.2015.39.5.363

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
  • [Journal Article] A novel and selective SGLT2 inhibitor, tofogliflozin, improves glycemic control and lowers body weight in patients with type 2 diabetes mellitus.2015

    • Author(s)
      Ikeda S, Takano Y, Cynshi O, Tanaka R, Christ AD, Boerlin V, Beyer U, Beck A, Ciorciaro C, Meyer M, Kadowaki T
    • Journal Title

      Diabetes Obes. Metab.

      Volume: 17 Issue: 10 Pages: 984-993

    • DOI

      10.1111/dom.12538

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Efficacy and safety of Empagliflozin monotherapy for 52 weeks in Japanese patients with type 2 diabetes : A randomized, double-blind, parallel-group study.2015

    • Author(s)
      Kadowaki T, Haneda M, Inagaki N, Terauchi Y, Taniguchi A, Koiwai K, Rattunde H, Woerle HJ, Broedl UC
    • Journal Title

      Adv. Ther.

      Volume: 32 Issue: 4 Pages: 306-318

    • DOI

      10.1007/s12325-015-0198-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity.2015

    • Author(s)
      Okada-Iwabu M, Iwabu M, Ueki K, Yamauchi T, Kadowaki T
    • Journal Title

      Diabetes Metab J

      Volume: 39 Pages: 363-372

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26253058
  • [Journal Article] Sitagliptin improves glycemic excursion after a meal or after an oral glucose load in Japanese subjects with impaired glucose tolerance.2015

    • Author(s)
      Kaku K, Kadowaki T, Terauchi Y, Okamoto T, Sato A, Okuyama K, Arjona Ferreira JC and Goldstein BJ
    • Journal Title

      Diabetes Obes. Metab.

      Volume: 17 Issue: 11 Pages: 1033-1041

    • DOI

      10.1111/dom.12507

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Crystal structures of the human adiponectin receptors.2015

    • Author(s)
      Tanabe H, Fujii Y, Okada-Iwabu M, Iwabu M, Nakamura Y, Hosaka T, Motoyama K, Ikeda M, Wakiyama M, Terada T, Ohsawa N, Hato M, Ogasawara S, Hino T, Murata T, Iwata S, Hirata K, Kawano Y, Yamamoto M, Kimura-Someya T, Shirouzu M, Yamauchi T, Kadowaki T, Yokoyama S
    • Journal Title

      Nature

      Volume: 520 Issue: 7547 Pages: 312-316

    • DOI

      10.1038/nature14301

    • NAID

      40020952688

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01507, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-25711004, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
  • [Journal Article] Usefulness of measuring both body mass index and waist circumference for the estimation of visceral adiposity and related cardiometabolic risk profile (from the INSPIRE ME IAA Study)2015

    • Author(s)
      Nazare JA, Smith J, Borel AL, Aschner P, Barter P, Van Gaal L, Tan CE, Wittchen HU, Matsuzawa Y, Kadowaki T, …, Almeras N, Haffner SM, Balkau B, Després JP : INSPIRE ME IAA Investigators
    • Journal Title

      Am. J. Cardiol.

      Volume: 115 Issue: 3 Pages: 307-315

    • DOI

      10.1016/j.amjcard.2014.10.039

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoRl and AdipoR22015

    • Author(s)
      Tanabe H,..., Iwata S, Okada-Iwabu M, Iwabu M,..., Yamauchi T, Kadowaki T, and Yokoyama S
    • Journal Title

      J. Struct. Funct. Genomics

      Volume: 16 Issue: 1 Pages: 11-23

    • DOI

      10.1007/s10969-014-9192-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032
  • [Journal Article] Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from γδ-T cells.2015

    • Author(s)
      ・Shibata S, Tada Y, Hau CS, Mitsui A, Kamata M, Asano Y, Sugaya M, Kadono T, Masamoto Y, Kurokawa M, Yamauchi T, Kubota N, Kadowaki T, Sato S
    • Journal Title

      Nat Commun

      Volume: 6 Pages: 7687-7687

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Journal Article] Effects of beraprost sodium, an oral prostacyclin analog, on insulin resistance in patients with type 2 diabetes.2015

    • Author(s)
      Katsuyama H, Kubota N, Kubota T, Haraguchi M, Obata A, Takamoto I, Shigematsu K, Miyata T, Ueki K, Kadowaki T
    • Journal Title

      Diabetol. Int.

      Volume: 6 Issue: 1 Pages: 39-45

    • DOI

      10.1007/s13340-014-0169-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Insulin receptor substrate-2 (irs2) in endothelial cells plays a crucial role in insulin secretion2015

    • Author(s)
      Hashimoto, S. Kubota, N. Sato, H. Sasaki, M. Takamoto, I. Kubota, T. Nakaya, K. Noda, M. Ueki, K. Kadowaki, T.
    • Journal Title

      Diabetes

      Volume: 64 Issue: 3 Pages: 876-886

    • DOI

      10.2337/db14-0432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249053, KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-25461371, KAKENHI-PROJECT-26000012
  • [Journal Article] Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from γ δ-T cells.2015

    • Author(s)
      Shibata S, Tada Y, Hau CS, Mitsui A, Kamata M, Asano Y, Sugaya M, Kadono T, Masamoto Y, Kurokawa M, Yamauchi T, Kubota N, Kadowaki T, Sato S
    • Journal Title

      Nat. Commun.

      Volume: 6 Pages: 7687-7687

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Successfully achieving target weight loss influences subsequent maintenance of lower weight and dropout from treatment2015

    • Author(s)
      Yamada T, Hara K, Svensson A, Shojima N, Hosoe J, Iwasaki M, Yamauchi T, Kadowaki T
    • Journal Title

      Obesity(Silver Spring)

      Volume: 23 Issue: 1 Pages: 183-191

    • DOI

      10.1002/oby.20874

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-26253058
  • [Journal Article] Sirtuin1 Maintains Actin Cytoskeleton by Deacetylation of Cortactin in Injured Podocytes.2015

    • Author(s)
      ・Motonishi S, Nangaku M, Wada T, Ishimoto Y, Ohse T, Matsusaka T, Kubota N, Shimizu A, Kadowaki T, Tobe K, Inagi R
    • Journal Title

      J Am Soc Nephrol

      Volume: 26 Pages: 1939-1959

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Journal Article] Hemoglobin A1c levels and the risk of cardiovascular disease in people without known diabetes: a population-based cohort study in Japan2015

    • Author(s)
      Goto A, Noda M, Matsushita Y, Goto M, Kato M, Isogawa A, Takahashi Y, Kurotani K, Oba S, Nanri A, Mizoue T, Yamagishi K, Yatsuya H, Saito I, Kokubo Y, Sawada N, Inoue M, Iso H, Kadowaki T, Tsugane S
    • Journal Title

      Medicine (Baltimore)

      Volume: 94 Issue: 17 Pages: e785-e785

    • DOI

      10.1097/md.0000000000000785

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26253043, KAKENHI-PROJECT-26000012
  • [Journal Article] Safety and efficacy of teneligliptin in Japanese patients with type 2 diabetes mellitus : a pooled analysis of two Phase III clinical studies.2015

    • Author(s)
      Kadowaki T, Marubayashi F, Yokota S, Katoh M, Iijima H
    • Journal Title

      Expert Opin. Pharmacother.

      Volume: 16 Issue: 7 Pages: 971-981

    • DOI

      10.1517/14656566.2015.1032249

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] IL-1 alpha induces rapid enhanced platelet biogenesis through rupture of Running title: Rupture thrombopoiesis regulated by IL-1alpha murine bone marrow megakaryocytes2015

    • Author(s)
      Satoshi Nishimura, Mika Nagasaki, Shinji Kunishima, Asuka Sakata, Hiroyasu Sakaguchi, Naoya Takayama, Issei Komuro, Joe Italiano Jr., Tomiko Ryu, Tsukasa Ohmori, Takashi Kadowaki, Koji Eto, Ryozo Nagai
    • Journal Title

      Journal of cell biology

      Volume: 未 Issue: 3 Pages: 453-66

    • DOI

      10.1083/jcb.201410052

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461356, KAKENHI-PROJECT-26461413, KAKENHI-PROJECT-15H03005, KAKENHI-PROJECT-26713013, KAKENHI-PROJECT-26000012
  • [Journal Article] A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice.2015

    • Author(s)
      Shiomi Y, Yamauchi T, Iwabu M, Okada-Iwabu M, Nakayama R, Orikawa Y, Yoshioka Y, Tanaka K, Ueki K, Kadowaki T
    • Journal Title

      J Biol Chem

      Volume: 290 Issue: 23 Pages: 14567-14581

    • DOI

      10.1074/jbc.m114.622191

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01507, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-23228001, KAKENHI-PROJECT-24249077, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26282223, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
  • [Journal Article] L-cysteine reversibly inhibits glucose-induced biphasic insulin secretion and ATP production by inactivating PKM2.2015

    • Author(s)
      ・Nakatsu D, Horiuchi Y, Kano F, Noguchi Y, Sugawara T, Takamoto I, Kubota N, Kadowaki T, Murata M
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 112 Pages: 1067-1076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Journal Article] Visceral, subcutaneous abdominal adiposity and liver fat content distribution in normal glucose tolerance, impaired fasting glucose and/orimpaired glucose tolerance.2015

    • Author(s)
      Borel AL, Nazare JA, Smith J, Aschner P, Barter P, Van Gaal L, …, Kadowaki T, Ross R, Brulle-Wohlhueter C, Alméras N, Haffner SM, Balkau B, Després JP for the INSPIRE ME IAA investigators :
    • Journal Title

      Int. J. Obes. (Lond)

      Volume: 39 Issue: 3 Pages: 495-501

    • DOI

      10.1038/ijo.2014.163

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Effects of beraprost sodium, an oral prostacyclin analog, on insulin resistance in patients with type 2 diabetes.2015

    • Author(s)
      ・Katsuyama H, Kubota N, Kubota T, Haraguchi M, Obata A, Takamoto I, Shigematsu K, Miyata T, Ueki K, Kadowaki T
    • Journal Title

      Diabetol. Int.

      Volume: 6 Pages: 39-45

    • NAID

      40020406077

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Journal Article] TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass.2014

    • Author(s)
      Takamoto I, Kubota N, Nakaya K, Kumagai K, Hashimoto S, Kubota T, Inoue M, Kajiwara E, Katsuyama H, Obata A, Sakurai Y, Iwamoto M, Kitamura T, Ueki K, Kadowaki T
    • Journal Title

      Diabetologia

      Volume: 57 Issue: 3 Pages: 542-553

    • DOI

      10.1007/s00125-013-3131-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25461371, KAKENHI-PROJECT-25860741
  • [Journal Article] Vagal hyperactivity due to ventromedial hypothalamic lesions increases adiponectin production and release.2014

    • Author(s)
      Suzuki Y, Shimizu H, Ishizuka N, Kubota N, Kubota T, Senoo A, Kageyama H, Osaka T, Hirako S, Kim HJ, Matsumoto A, Shioda S, Mori M, Kadowaki T, Inoue S.
    • Journal Title

      Diabetes.

      Volume: 63(5) Issue: 5 Pages: 1637-1648

    • DOI

      10.2337/db13-0636

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22126004, KAKENHI-PLANNED-22126010, KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-24590241, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25461371, KAKENHI-PROJECT-25670767, KAKENHI-PROJECT-25750053, KAKENHI-PROJECT-26000012
  • [Journal Article] Ethnic differences in insulin sensitivity, beta-cell function, and hepatic extraction between Japanese and Caucasians: a minimal model analysis2014

    • Author(s)
      Moller, J. B. Dalla Man, C. Overgaard, R. V. Ingwersen, S. H. Tornoe, C. W. Pedersen, M. Tanaka, H. Ohsugi, M. Ueki, K. Lynge, J. Vasconcelos, N. M. Pedersen, B. K. Kadowaki, T. Cobelli, C.
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 99 Issue: 11 Pages: 4273-4280

    • DOI

      10.1210/jc.2014-1724

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249053, KAKENHI-PROJECT-26000012
  • [Journal Article] Sirtuinl Maintains Actin Cytoskeleton by Deacetylation of Cortactin in Injured Podocytes2014

    • Author(s)
      Motonishi S, Nangaku M, Wada T, Ishimoto Y, Ohse T, Matsusaka T, Kubota N, Shimizu A, Kadowaki T, Tobe K, Inagi R
    • Journal Title

      J. Am. Soc. Nephrol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Genome-wide association study identifies three novel loci for type 2 diabetes2014

    • Author(s)
      Hara K, Fujita H, Johnson TA, Yamauchi T, Yasuda K, Horikoshi M, Peng C, Hu C, Ma RC, Imamura M, et al
    • Journal Title

      Hum Mol Genet

      Volume: 23 Issue: 1 Pages: 239-246

    • DOI

      10.1093/hmg/ddt399

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591361, KAKENHI-PROJECT-24510276, KAKENHI-PROJECT-25221307
  • [Journal Article] Silent myocardial ischaemia in patients with diabetic retinopathy2014

    • Author(s)
      Ohtomo K, Shigeeda T, Hirose A, Ohno T, Kinoshita O, Fujita H, Ando J, Nagai R, Takamoto S, Kadowaki T, Kato S
    • Journal Title

      Acta Ophthalmol

      Volume: 92 Issue: 6

    • DOI

      10.1111/aos.12362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Deregulation of Pancreas-Specific Oxidoreductin ERO1beta in the Pathogenesis of Diabetes Mellitus2014

    • Author(s)
      Awazawa, M. Futami, T. Sakada, M. Kaneko, K. Ohsugi, M. Nakaya, K. Terai, A. Suzuki, R. Koike, M. Uchiyama, Y. Kadowaki, T. Ueki, K.
    • Journal Title

      Mol Cell Biol

      Volume: 34 Issue: 7 Pages: 1290-1299

    • DOI

      10.1128/mcb.01647-13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249053, KAKENHI-PROJECT-25461373, KAKENHI-PROJECT-26000012
  • [Journal Article] Empagliflozin Monotherapy in Japanese Patients with Type 2 Diabetes Mellitus: a Randomized, 12-Week, Double-Blind, Placebo-Controlled, Phase II Trial.2014

    • Author(s)
      Kadowaki T, Haneda M, Inagaki N, Terauchi Y, Taniguchi A, Koiwai K, Rattunde H, Woerle HJ, Broedl UC
    • Journal Title

      Advances in Therapy

      Volume: 31 Issue: 6 Pages: 621-638

    • DOI

      10.1007/s12325-014-0126-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Journal Article] Genetic architecture of type 2 diabetes2014

    • Author(s)
      Hara K, Shojima N, Hosoe J, Kadowaki T
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 452 Issue: 2 Pages: 213-220

    • DOI

      10.1016/j.bbrc.2014.08.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Journal Article] Adiponectin and its receptors: Implications for obesity-associated diseases and longevity2014

    • Author(s)
      Kadowaki T, Yamauchi T, Okada-Iwabu M, Iwabu M
    • Journal Title

      Lancet Diabetes Endocrinol.

      Volume: 2 Issue: 1 Pages: 8-9

    • DOI

      10.1016/s2213-8587(13)70120-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-23689048, KAKENHI-PROJECT-24790908
  • [Journal Article] Association Between Plasma Triglycerides and High-Density Lipoprotein Cholesterol and Microvascular Kidney Disease and Retinopathy in Type 2 Diabetes Mellitus : A Global Case–Control Study in 13 Countries2014

    • Author(s)
      Sacks FM, ..., Kadowaki T, ..., Carey VJ
    • Journal Title

      Circulation

      Volume: 122 Issue: 9 Pages: 999-1008

    • DOI

      10.1161/circulationaha.113.002529

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Journal Article] Evi1 defines leukemia-initiating capacity and tyrosine kinase inhibitor resistance in chronic myeloid leukemia.2014

    • Author(s)
      Sato T, Goyama S, Kataoka K, Nasu R, Tsuruta-Kishino T, Kagoya Y, Nukina A, Kumagai K, Kubota N, Nakagawa M, Arai S, Yoshimi A, Honda H, Kadowaki T, Kurokawa M.
    • Journal Title

      Oncogene

      Volume: 33 Issue: 42 Pages: 5028-5038

    • DOI

      10.1038/onc.2014.108

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-24790962, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-26670464, KAKENHI-PROJECT-26860474, KAKENHI-PROJECT-26860721
  • [Journal Article] Residual macrovascular risk in 2013: what have we learned?2014

    • Author(s)
      Fruchart JC, ..., Kadowaki T, ..., Zimmet P
    • Journal Title

      Cardiovasc. Diabetol.

      Volume: 13 Issue: 1 Pages: 26-26

    • DOI

      10.1186/1475-2840-13-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Journal Article] Adiponectin receptors: A review of their structure, function and how they work2014

    • Author(s)
      Yamauchi T, Iwabu M, Okada-Iwabu M, Kadowaki T
    • Journal Title

      Best Pract. Res. Clin. Endocrinol. Metab.

      Volume: 28 Issue: 1 Pages: 15-23

    • DOI

      10.1016/j.beem.2013.09.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-23689048, KAKENHI-PROJECT-24790908
  • [Journal Article] A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.2013

    • Author(s)
      Okada-Iwabu M, Yamauchi T, Iwabu M, Honma T, Hamagami K, Matsuda K, Yamaguchi M, Tanabe H, Kimura-Someya T, Shirouzu M, Ogata H, Tokuyama K, Ueki K, Nagano T, Tanaka A, Yokoyama S and Kadowaki T.
    • Journal Title

      Nature

      Volume: 503 Issue: 7477 Pages: 493-499

    • DOI

      10.1038/nature12656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249053, KAKENHI-PROJECT-24700694, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-23689048, KAKENHI-PROJECT-24790908
  • [Journal Article] Male pattern baldness and its association with coronary heart disease: a meta-analysis.2013

    • Author(s)
      Yamada T, Hara K, Umematsu H, Kadowaki T
    • Journal Title

      BMJ Open.

      Volume: 3 Issue: 4 Pages: e002537-e002537

    • DOI

      10.1136/bmjopen-2012-002537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253068
  • [Journal Article] Body composition is main determinant for the difference in Type 2 diabetese pathophysiology between Japanese and Caucasians.2013

    • Author(s)
      Moller J, Pedersen M, Tanaka H, Ohsugi M, Overgaard R, Lynge J Almind K, Vasconcelos Nina-Maria, Poulsen P, Keller C, Ueki K, Ingwersen S, Pedersen B, Kadowaki T
    • Journal Title

      Diabetes Care

      Volume: 37 Issue: 3 Pages: 796-804

    • DOI

      10.2337/dc13-0598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Journal Article] Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization.2013

    • Author(s)
      Izumida Y, Yahagi N, Takeuchi Y, Nishi M, Shikama A, Takarada A, Masuda Y, Kubota M, Matsuzaka T, Nakagawa Y, Iizuka Y, Itaka K, Kataoka K, Shioda S, Niijima A, Yamada T, Katagiri H, Nagai R, Yamada N, Kadowaki T, Shimano H
    • Journal Title

      Nat Commun.

      Volume: 4 Issue: 1 Pages: 2316-2316

    • DOI

      10.1038/ncomms3316

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22126004, KAKENHI-PLANNED-22126006, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23591293, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24659439, KAKENHI-PROJECT-24680072, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461332, KAKENHI-PROJECT-25670430
  • [Journal Article] The role of endothelial insulin signaling in the regulation of glucose metabolism.2013

    • Author(s)
      Kubota T, Kubota N, Kadowaki T
    • Journal Title

      Rev. Endocr. Metab. Disord.

      Volume: 14 Issue: 2 Pages: 207-216

    • DOI

      10.1007/s11154-013-9242-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25253068, KAKENHI-PROJECT-25461371
  • [Journal Article] Baseline predictive factors for glycemic control in Japanese type 2 diabetes patients treated with insulin glargine plus oral antidiabetic drugs: ALOHA study subanalysis2013

    • Author(s)
      Kadowaki T, Ohtani T, Odawara M.
    • Journal Title

      Diabetol Int

      Volume: 4 Pages: 16-22

    • NAID

      10030925706

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4.2013

    • Author(s)
      6. Ma R. C. W., Hu C., Tam C. H., …Kadowaki T., Tai E. S., Zeggini E., McCarthy M. I., Hon K. L., Baum L., Tomlinson B., So W. Y., Bao Y., Chan J. C. N., Jia W:
    • Journal Title

      Diabetologia

      Volume: 56 Issue: 6 Pages: 1291-1305

    • DOI

      10.1007/s00125-013-2874-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253068
  • [Journal Article] Sweat gland atrophy of the heel in diabetic patients with angiopathy.2013

    • Author(s)
      Oe M, Sanada H, Nagase T, Minematsu T, Ohashi Y, Kadono T, Ueki K, Kadowaki T
    • Journal Title

      J. Clin. Nurs.

      Volume: 22 Issue: 1-2 Pages: 289-292

    • DOI

      10.1111/j.1365-2702.2012.04267.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Journal Article] Dipeptidyl peptidase-4 inhibitor anagliptin ameliorates diabetes in mice with haploinsufficiency of glucokinase on a high-fat diet.2013

    • Author(s)
      Nakaya K, Kubota N, Takamoto I, Kubota T, Katsuyama H, Sato H, Tokuyama K, Hashimoto S, Goto M, Jomori T, Ueki K, Kadowaki T
    • Journal Title

      Metabolism

      Volume: 62 Issue: 7 Pages: 939-951

    • DOI

      10.1016/j.metabol.2013.01.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25253068, KAKENHI-PROJECT-25461371
  • [Journal Article] Baseline predictive factors for glycemic control in Japanese type 2 diabetes patients treated with insulin glargine plus oral antidiabetic drugs: ALOHA study subanalysis.2013

    • Author(s)
      Kadowaki T, Ohtani T, Odawara M
    • Journal Title

      Diabetol Int.

      Volume: 4 Pages: 16-22

    • NAID

      10030925706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Adiponectin receptor as a key player in healthy longevity and obesity-related diseases2013

    • Author(s)
      Yamauchi T, Kadowaki T.
    • Journal Title

      Cell Metab

      Volume: 17 Issue: 2 Pages: 185-196

    • DOI

      10.1016/j.cmet.2013.01.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Efficacy, safety and dose-desponse relationship of teneligliptin, a dipeptidyl peptidase-4 inhibitor, in Japanese patients with type 2 diabetes mellitus2013

    • Author(s)
      Kadowaki T, Kondo K.
    • Journal Title

      Diabetes Obes Metab

      Volume: - Issue: 9 Pages: 810-818

    • DOI

      10.1111/dom.12092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Apolipoprotein C-II deficiency with no rare variant in the APOC2 gene.2013

    • Author(s)
      Takase S, Osuga J, Fujita H, Hara K, Sekiya M, Igarashi M, Takanashi M, Takeuchi Y, Izumida Y, Ohta K, Kumagai M, Nishi M, Kubota M, Masuda Y, Taira Y, Okazaki S, Iizuka Y, Yahagi N, Ohashi K, Yoshida H, Yanai H, Tada N, Gotoda T, Ishibashi S, Kadowaki T, Okazaki H
    • Journal Title

      J. Atheroscler. Thromb.

      Volume: 20 Pages: 481-493

    • NAID

      130004444688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Journal Article] A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site.2013

    • Author(s)
      Nabeno M, Akahoshi F, Kishida H, Miyaguchi I, Tanaka Y, Ishii S, Kadowaki T
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 434 Issue: 2 Pages: 191-196

    • DOI

      10.1016/j.bbrc.2013.03.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-25253068
  • [Journal Article] Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX42013

    • Author(s)
      Ma R. C. W., Hu C., Tam C. H.,..., Hara K.,..., Yamauchi T.,..., Kadowaki T., Tai E. S., Zeggini E., McCarthy M. I., Hon K. L., Baum L., Tomlinson B., So W. Y., Bao Y., Chan J. C. N., Jia W
    • Journal Title

      Diabetologia

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Morphological pattern classification system for plantar thermography of patients with Diabetes.2013

    • Author(s)
      Mori T, Nagase T, Takehara K, Oe M, Ohashi Y, Amemiya A, Noguchi H, Ueki K, Kadowaki T, Sanada H
    • Journal Title

      J. Diabetes Sci. Technol.

      Volume: 7 Pages: 1102-1112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Journal Article] Genome-wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India2013

    • Author(s)
      Saxena R, Yamauchi T, Hara K Saxena R, Yamauchi T, Hara K DIAGRAM MuTHER; TGEN, Kadowaki T
    • Journal Title

      Diabetes

      Volume: 62 Issue: 5 Pages: 1746-1755

    • DOI

      10.2337/db12-1077

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-23591327, KAKENHI-PROJECT-24510276, KAKENHI-PROJECT-25253068
  • [Journal Article] Saturated fatty acid and TLR signaling link (3 cell dysfunction and islet inflammation2012

    • Author(s)
      Eguchi K, Kadowaki T
    • Journal Title

      Cell Metal

      Volume: 15 Pages: 518-533

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Erectile dysfunction and cardiovascular events in diabetic menmeta-analysis of observational studies2012

    • Author(s)
      Yamada T, Hara K, Umematsu H, Suzuki R, Kadowaki T.
    • Journal Title

      PLoS One

      Volume: 7 Issue: 9 Pages: e43673-e43673

    • DOI

      10.1371/journal.pone.0043673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-23689047
  • [Journal Article] Monocyte chemoattractant protein-1 (MCP-1) deficiency enhances alternatively activated M2 macrophages and ameliorates insulin resistance and fatty liver in lipoatrophic diabetic A-ZIP transgenic mice2012

    • Author(s)
      Nio Y, Yamauchi T, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
    • Journal Title

      Diabetologia

      Volume: 55 Issue: 12 Pages: 3350-3358

    • DOI

      10.1007/s00125-012-2710-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-23689048, KAKENHI-PROJECT-24790908
  • [Journal Article] Potential Formula for the Calculation of Starting and Incremental Insulin Glargine Doses: ALOHA Subanalysis2012

    • Author(s)
      Kadowaki T, Ohtani T, Odawara M
    • Journal Title

      PLoSOne

      Volume: 7 Issue: 7 Pages: e41353-e41353

    • DOI

      10.1371/journal.pone.0041353

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Association of adenovirus 36 infection with obesity and metabolic markers in humans: a meta-analysis of observational studies.2012

    • Author(s)
      Yamada T, Hara K, Kadowaki T
    • Journal Title

      PLoS One

      Volume: 7 Issue: 7 Pages: e42031-e42031

    • DOI

      10.1371/journal.pone.0042031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits2012

    • Author(s)
      Fujita H, Hara K, Kadowaki T
    • Journal Title

      J Hum Genet

      Volume: 57 Issue: 12 Pages: 776-779

    • DOI

      10.1038/jhg.2012.110

    • NAID

      10031145885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22790862, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24510276
  • [Journal Article] Cntrol of beta cell function and proliferation in mice stimulated by small-molecule glucokinase activator under various conditions2012

    • Author(s)
      Nakamura A, Kubota N, Kadowaki T
    • Journal Title

      Diabatologia

      Volume: 55 Pages: 1745-1754

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Control of beta cell function and proliferation in mice stimulated by small-molecule glucokinase activator under various conditions2012

    • Author(s)
      Nakamura A, Togashi Y, Orime K, Sato K, Shirakawa J, Ohsugi M, Kubota N, Kadowaki T, Terauchi Y
    • Journal Title

      Diabetologia

      Volume: (In press) Issue: 6 Pages: 1745-1754

    • DOI

      10.1007/s00125-012-2521-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J03269, KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-23591315, KAKENHI-PROJECT-23791040, KAKENHI-PROJECT-24390232
  • [Journal Article] Expression-based genome-gide association study links CD44 in adipose tissue with type 2 diabetes2012

    • Author(s)
      Kodama K, Hara K, Kadowaki T, Butte AJ
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 109 Issue: 18 Pages: 7049-7054

    • DOI

      10.1073/pnas.1114513109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] SnapShot: Physiology of Insulin Signaling2012

    • Author(s)
      Kadowaki T, Kubota N, Ueki K, Yamauchi T
    • Journal Title

      Ce11

      Volume: 148 Pages: 834-834

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.2012

    • Author(s)
      Imamura M, Maeda S, Yamauchi T, Hara K, Yasuda K,..., Okada-Iwabu M, Iwabu M, Shojima N,..., Nakamura Y, Kadowaki T
    • Journal Title

      Human Molecular Genetics

      Volume: 21 Issue: 13 Pages: 3042-3049

    • DOI

      10.1093/hmg/dds113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22591021, KAKENHI-PROJECT-23591361, KAKENHI-PROJECT-24510276, KAKENHI-PROJECT-23689048, KAKENHI-PROJECT-24790908
  • [Journal Article] SnapShot : Physiology of Insulin Signaling2012

    • Author(s)
      Kadowaki T, Kubota N, Ueki K, Yamauchi T
    • Journal Title

      Cell

      Volume: 148 Issue: 4 Pages: 834-834

    • DOI

      10.1016/j.cell.2012.02.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Depletion of homeodomain-interacting protein kinase 3 impairs insulin secretion and glucose tolerance in mice2012

    • Author(s)
      Shojima N, Hara K, Kubota N, Yamauchi T, Ueki K, Kadowaki T
    • Journal Title

      Diabetologia

      Volume: 55 Issue: 12 Pages: 3318-3330

    • DOI

      10.1007/s00125-012-2711-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Potential Formula for the Calculation of Starting and Incremental Insulin Glargine Doses: ALOHA Subanalysis.2012

    • Author(s)
      Kadowaki T, Ohtani T, Odawara M
    • Journal Title

      PLoS One

      Volume: 7 Issue: 8 Pages: e41358-e41358

    • DOI

      10.1371/journal.pone.0041358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Genetic risk score constructed using 14 susceptibility alleles for type 2 diabetes is associated with the early onset of diabetes and may predict the future requirement of insulin injections among Japanese individuals2012

    • Author(s)
      Iwata M, Hara K, Kadowaki T
    • Journal Title

      Diabetes Care

      Volume: 35 Issue: 8 Pages: 1763-1770

    • DOI

      10.2337/dc11-2006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22591021, KAKENHI-PROJECT-24510276
  • [Journal Article] Snap Shot: Insulin Signaling Pathways2012

    • Author(s)
      Kadowaki T, Ueki K, Yamauchi T, Kubota N.
    • Journal Title

      Cep

      Volume: 148 Pages: 624-624

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation.2012

    • Author(s)
      Eguchi K, Manabe I, Oishi-Tanaka Y, Ohsugi M, Kono N, Ogata F, Yagi N, Ohto U, Kimoto M, Miyake K, Tobe K, Arai H, Kadowaki T, Nagai R
    • Journal Title

      Cell Metab.

      Volume: 15 Issue: 4 Pages: 518-533

    • DOI

      10.1016/j.cmet.2012.01.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PUBLICLY-22117504, KAKENHI-PROJECT-22229006, KAKENHI-PROJECT-22790691, KAKENHI-PUBLICLY-23113707, KAKENHI-PUBLICLY-23121510, KAKENHI-PROJECT-23227004, KAKENHI-PROJECT-23770106, KAKENHI-PLANNED-21117002, KAKENHI-PUBLICLY-24117703
  • [Journal Article] SnapShot : Insulin Signaling Pathways2012

    • Author(s)
      Kadowaki T, Ueki K, Yamauchi T, Kubota N
    • Journal Title

      Cell

      Volume: 148 Issue: 3 Pages: 624-624

    • DOI

      10.1016/j.cell.2012.01.034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] The other sweet face of XBP-12011

    • Author(s)
      Ueki K, Kadowaki T
    • Journal Title

      Nature Medicine

      Volume: 17 Issue: 3 Pages: 246-248

    • DOI

      10.1038/nm0311-246

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage妖erived IL-6 dependent pathway2011

    • Author(s)
      Awazawa M, Ueki K, Yamauchi T, Kubota, Kadowaki T
    • Journal Title

      Cell Metabolism

      Volume: 13 Issue: 4 Pages: 401-412

    • DOI

      10.1016/j.cmet.2011.02.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-23791019
  • [Journal Article] Possibility of increasing cholesterol efflux by adiponectin and its receptors through the ATP binding cassette transporter A1 in HEK293T cells2011

    • Author(s)
      Kitajima, K,Miura S, Yamauchi T, Uehara Y, Kiya Y, Rye KA, Kadowaki T, Saku K
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 411 Issue: 2 Pages: 305-311

    • DOI

      10.1016/j.bbrc.2011.06.131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle.2011

    • Author(s)
      Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T
    • Journal Title

      Cell Metabolism 13

      Pages: 294-307

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle2011

    • Author(s)
      Kubota T, Kubota N, Ueki K, Kadowaki T
    • Journal Title

      Cell Metabolism

      Volume: 13 Pages: 294-307

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance2011

    • Author(s)
      Kobayashi N, Ueki K, Okazaki Y, Iwane A, Kubota N, Ohsugi M, Awazawa M, Kobayashi M, Sasako T, Kaneko K, Suzuki M, Nishikawa Y, Hara K, Yoshimura K, Koshima I, Goyama s, Murakami K, Sasaki J, Nagai R, Kurokawa M, Sasaki T, Kadowaki T
    • Journal Title

      Proc.Natl.Acad.Sci.USA

      Volume: 108 Issue: 14 Pages: 5753-5758

    • DOI

      10.1073/pnas.1016430108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21200075, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-21591124
  • [Journal Article] The other sweet face of XBP-1.2011

    • Author(s)
      Ueki K, Kadowaki T.
    • Journal Title

      Nature Med.

      Volume: 17 Pages: 246-248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity2011

    • Author(s)
      Keisuke Kataoka
    • Journal Title

      The Journal of Experimental Medicine

      Volume: 208 Issue: 12 Pages: 2403-2416

    • DOI

      10.1084/jem.20110447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J04996, KAKENHI-PROJECT-19679004, KAKENHI-PROJECT-20229008, KAKENHI-PUBLICLY-23130503, KAKENHI-PROJECT-23591369
  • [Journal Article] Thiazolidinediones Enhance Sodium-Coupled Bicarbonate Absorption from Renal Proximal Tubules via PPARγ-Dependent Nongenomic Signaling2011

    • Author(s)
      Endo Y, Suzuki M, Yamada H, Horita s, Kunimi M, Yamazaki O, Shirai A, Nakamura M, Iso-O N, Li Y, Hara M, Tsukamoto K, Moriyama N, Kudo A, Kawakami H, Yamauchi T, Kubota N, Kadowaki T, Kume H, Enomoto Y, Homma Y, Seki G, Fujita T
    • Journal Title

      Cell Metabolism

      Volume: 13 Pages: 550-561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling2011

    • Author(s)
      S.Nishimura
    • Journal Title

      Blood

      Volume: 119 Issue: 8 Pages: 128-131

    • DOI

      10.1182/blood-2011-09-381400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21300160, KAKENHI-PROJECT-21390321, KAKENHI-PROJECT-21590230, KAKENHI-PROJECT-21591231, KAKENHI-PROJECT-22300106, KAKENHI-PROJECT-22700448, KAKENHI-PUBLICLY-23114504, KAKENHI-PROJECT-23591298, KAKENHI-PROJECT-23650214, KAKENHI-PROJECT-23650622, KAKENHI-PROJECT-23659514, KAKENHI-PROJECT-23659533, KAKENHI-PROJECT-23791016, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-24659489, KAKENHI-PROJECT-24659522
  • [Journal Article] Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle.2011

    • Author(s)
      Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itch S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki 0, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, TsutsuiM, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T.
    • Journal Title

      Cell Metab.

      Volume: 13 Pages: 294-307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Loss of adiponectin promotes intestinal carcinogenesis in Min and wild-type mice2011

    • Author(s)
      Mutoh M, Kubota N, Kadowaki T
    • Journal Title

      Gastroenterology

      Volume: 140 Issue: 7 Pages: 2000-2008

    • DOI

      10.1053/j.gastro.2011.02.019

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Adiponectin receptor signaling : a new layer to the current model.2011

    • Author(s)
      Kadowaki T, Yamauchi T.
    • Journal Title

      Cell Metab.

      Volume: 13 Pages: 123-124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Blockade of class lB phosphor inositide-3 kinase ameliorates obesity induced inflammation and insulin resistance2011

    • Author(s)
      Kobayashi N, Ueki, Kubota N, Hara K, Kadowaki T
    • Journal Title

      Proc. Nat/. Acad. Sci. U.S.A.

      Volume: 108 Pages: 5753-5758

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via macrophage-derived IL-6 dependent pathway.2011

    • Author(s)
      Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, Kaneko K, Kobayashi M, Iwane A, Sasako T, Ohsugi M, Takamoto I, Yamashita S, Asahara H, Akira S, Kasuga M, Kadowaki T
    • Journal Title

      Cell Metabolism 13

      Pages: 401-412

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Apoptosis inhibitor of macrophage (AIM) is required for obesity-associated recruitment of inflammatory macrophages into adipose tissue2011

    • Author(s)
      Jun Kurokawa, et al
    • Journal Title

      Proc.Natl.Acad.Sci.USA.

      Volume: vol.108 Issue: 29 Pages: 12072-12077

    • DOI

      10.1073/pnas.1101841108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04681, KAKENHI-PROJECT-20229008
  • [Journal Article] The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals2011

    • Author(s)
      Grarup N, Yamauchi T, Hara K, Kadowaki T
    • Journal Title

      Diabetologia

      Volume: 54 Issue: 4 Pages: 789-794

    • DOI

      10.1007/s00125-010-2031-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Adiponectin receptor signaling: a new layer to the current model2011

    • Author(s)
      Kadowaki T, Yamauchi T
    • Journal Title

      Cell Metabolism

      Volume: 13 Issue: 2 Pages: 123-124

    • DOI

      10.1016/j.cmet.2011.01.012

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Crystal structure of the Ca2+/Calmodulin-dependent protein kinase in complex with the inhibitor STO-6092011

    • Author(s)
      Kukimoto-Nino M, Yamauchi T, Okada Iwabu M, Iwabu M, Kadowaki T
    • Journal Title

      J. Biol. Chem.

      Volume: 286 Issue: 25 Pages: 22570-22579

    • DOI

      10.1074/jbc.m111.251710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390067, KAKENHI-PROJECT-23689048
  • [Journal Article] Metabolomic analysis reveals hepatic metabolite perturbations in citrin/mitochondrial glycerol-3-phosphate dehydrogenase double-knockout mice, a model of human citrin deficiency2011

    • Author(s)
      Saheki T, Inoue K, Ono H, Tushima A, Katsura N, Yokogawa M, Yoshidumi Y, Kuhara T, Ohse M, Eto K, Kadowaki T, Sinasac DS, Kobayashi K
    • Journal Title

      Mol Genet Metab

      Volume: 104 Issue: 4 Pages: 492-500

    • DOI

      10.1016/j.ymgme.2011.08.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle2011

    • Author(s)
      Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T
    • Journal Title

      Cell Metabolism

      Volume: 13 Pages: 294-307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Journal Article] Global mapping of cell type-specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation2011

    • Author(s)
      Waki H, Nakamura M, Yamauchi T, Wakabayashi K, Yu J, Hirose-Yotsuya L, Take K, Sun W, Iwabu M, Okada-Iwabu M, Fujita T, Aoyama T, Tsutsumi S, Ueki K, Kodama T, Sakai J, Aburatani H, Kadowaki
    • Journal Title

      PLos Genetics

      Volume: 7 Issue: 10 Pages: e1002311-e1002311

    • DOI

      10.1371/journal.pgen.1002311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J03451, KAKENHI-PROJECT-20221009, KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22229009, KAKENHI-PLANNED-23126101, KAKENHI-PROJECT-23791020, KAKENHI-PROJECT-23689048
  • [Journal Article] Dietary restriction; Standing up for sirtuins2010

    • Author(s)
      Baur JA, Kadowaki T
    • Journal Title

      Science

      Volume: 329 Issue: 5995 Pages: 1012-1015

    • DOI

      10.1126/science.329.5995.1012

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Class IA phosphatidylinositol 3-kinase in pancreatic b cells controls insulin secretion by multiple mechanisms.2010

    • Author(s)
      Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yoshida M, Kakei M, Kitamura T, Luo J, Kulkami RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T
    • Journal Title

      Cell Metabolism 12

      Pages: 619-632

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus2010

    • Author(s)
      Okamoto K,, Kadowaki T
    • Journal Title

      Am.J.Hum. Genet

      Volume: 86 Issue: 1 Pages: 54-64

    • DOI

      10.1016/j.ajhg.2009.12.009

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBEZE2 and C2CD4A-C2CD4B.2010

    • Author(s)
      Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M, Fujito H, Grarup N, Cauchi S, Ng DPK, Ma RCW, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-lwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR, Jorgensen T, Lauritzen T, Sandbak A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H, So WY, Beury D, Chan JCN, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwag A, Kawamori R, Kasuga M, Frogue P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki T
    • Journal Title

      Nature Genetics

      Volume: 42 Pages: 864-868

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Class IA phosphatidylinositol 3-kinase in pancreatic b cells controls insulin secretion by multiple mechanisms.2010

    • Author(s)
      Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yoshida M, Kakei M, Kitamura T, Luo J, Kulkami RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T
    • Journal Title

      Cell Metab.

      Volume: 12 Pages: 619-632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus.2010

    • Author(s)
      Okamoto K, Iwasaki N, Nishimura C, Doi K, Noiri E, Nakamura S, Tanizawa M, Ogata M, Fujimaki R, Grarup N, Pisinger C, Borch-Johnsen K, Lauritzen T, Sandbaek A, Hansen T, Yasuda K, Osawa H, Nanjo K, Kadowaki T, Kasuga M, Pedersen O, Fujita T, Kamatani N, Iwamoto Y, Tokunaga K
    • Journal Title

      Am J Hum Genet 86

      Pages: 54-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] A liver-derived secretory protein, selenoprotein p, causes insulin resistance.2010

    • Author(s)
      Misu H, Takamura T, Takayama H, Hayashi H, Matsuzawa-Nagata N, Kurita S, Ishikura K, Ando H, Takeshita Y, Ota T, Sakurai M, Yamashita T, Mizukoshi E, Yamashita T, Honda M, Miyamoto K, Kubota T, Kubota N, Kadowaki T, Kim HJ, Lee IK, Minokoshi Y, Saito Y, Takahashi K, Yamada Y, Takakura N, Kaneko S.
    • Journal Title

      Cell Metabolism

      Volume: 12 Pages: 483-495

    • NAID

      120002661942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Journal Article] Adiponectin and AdipoRl regulate PGCI and mitochondria by Ca^<2+> and AMPK/SIRTI.2010

    • Author(s)
      Iwabu M, Yamauchi T, Okada-lwabu M, Sato K, Nakagawa T, Funata M, Pamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, .Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T
    • Journal Title

      Nature

      Volume: 464 Pages: 1313-1319

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] A liver-derived secretory protein, selenoprotein P, causes insulin resistance2010

    • Author(s)
      Misu H, Kubota N, Kadowaki T
    • Journal Title

      Cell Metabolis

      Volume: 12 Pages: 483-495

    • NAID

      120002661942

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Colestilan monotherapy significantly improves glycaemic control and LDL cholesterol levels in patients with type 2 diabetes : a randomized double-blind placebo-controlled study.2010

    • Author(s)
      Kondo K, Kadowaki T
    • Journal Title

      Diabetes Obes Metab 12

      Pages: 246-251

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Class IA Phosphatidylinositol 3-Kinase in Pancreatic β Cells Controls Insulin Secretion by Multiple Mechanisms.2010

    • Author(s)
      Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yoshida M, Kakei M, Kitamura T, Luo J, Kulkarni RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T
    • Journal Title

      Cell Metab. 12(6)

      Pages: 619-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Journal Article] genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B2010

    • Author(s)
      Yamauchi T, Ham K, Iwabu M, Okada-Iwabu M, Kadowaki T
    • Journal Title

      Nature Genetics

      Volume: 42 Issue: 10 Pages: 864-868

    • DOI

      10.1038/ng.660

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associaed with human hypertension.2010

    • Author(s)
      Oishi Y, Manabe I, Imai Y, Hara K, Horikoshi M, Fujiu K, Tanaka T, Aizawa T, Kadowaki T, Nagai R
    • Journal Title

      FASEB J (published online Jan.26, 2010)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Macrophage-derived AIM is endocytosed into adipocytes and decreases lipid droplets via inhibition of fattty acid synthase activity.2010

    • Author(s)
      Kurokawa J, Arai S, Nakashima K, Nagano H, Nishijima A, Miyata K, Ose R, Mori M, Kubota N, Kadowaki T, Oike Y, Koga H, Febbraio M, Iwanaga T, Miyazaki T
    • Journal Title

      Cell Metab.

      Volume: 11 Pages: 479-492

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Adiponectin recceptors are downregulated in human gastric cancer.2010

    • Author(s)
      Otani K, Kitayama J, Kamei T, Soma D, Miyato H, Yamauchi T, Kadowaki T, Nagawa H
    • Journal Title

      J Gastroenterol.

      Volume: 45 Pages: 918-927

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin 11 and is associated with human hypertension2010

    • Author(s)
      Oishi Y, Hara K, Kadowaki T
    • Journal Title

      FASBB J

      Volume: 24 Issue: 6 Pages: 1780-1788

    • DOI

      10.1096/fj.09-146589

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Long-term pancreas allograft survival in simultaneous pancreas-kidney transplantation by era: UN OS registry analysis2010

    • Author(s)
      Waki K, Terasaki PI, Kadowaki T
    • Journal Title

      Diabetes Care

      Volume: 33 Issue: 8 Pages: 1789-1791

    • DOI

      10.2337/dc09-2276

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Decreased insulin secretion and accumulation of triglyceride in beta cells overexpressing a dominant-negative form of AMP-activated protein kinase.2010

    • Author(s)
      Okazaki Y, Eto K, Yamashita T, Okamoto M, Ohsugi M, Noda M, Terauchi Y, Ueki K, Kadowaki T
    • Journal Title

      Endocr J 57

      Pages: 141-52

    • NAID

      130004443612

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Class IA phosphatidylinositol 3-kinase in pancreatic beta cells controls insulin secretion by multiple mechanisms2010

    • Author(s)
      Kaneko K, Ueki K, Kadowaki T
    • Journal Title

      Cell Metabolism

      Volume: 12 Issue: 6 Pages: 619-632

    • DOI

      10.1016/j.cmet.2010.11.005

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Macrophage-derived AIM is endocytosed into adipocytes and decreases lipid droplets via inhibition of fattty acid synthase activity2010

    • Author(s)
      Kurokawa J, Kubota N, Kadowaki T
    • Journal Title

      Cell Metabolism

      Volume: 11 Issue: 6 Pages: 479-492

    • DOI

      10.1016/j.cmet.2010.04.013

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus.2010

    • Author(s)
      Okamoto, K., Yasuda, K. (16番目), Osawa, H. (17), Nanjo, K. (18), Kadowaki, T. (19), Kasuga, M. (20), ほか19名
    • Journal Title

      Am J Hum Genet 86(1)

      Pages: 54-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] A liver-derived secretory protein, selenoprotein P, causes insulin resistance.2010

    • Author(s)
      Misu H, Takamura T, Takayama H, Hayashi H, Matsuzawa-Nagata N, Kurita S, Ishikura K, Ando H, Takeshita Y, Ota T, Sakurai M, Yamashita T, Mizukoshi E, Yamashita T, Honda M, Miyamoto K, Kubota T, Kubota N, Kadowaki T, Kim HJ, Lee IK, Minokoshi Y, Saito Y, Takahashi K, Yamada Y, Takakura N, Kaneko S.
    • Journal Title

      Cell Metab.

      Volume: 12 Pages: 483-4951

    • NAID

      120002661942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatoryelement-binding protein-1 through proteolytic processing and autoloop regulatory circuit.2010

    • Author(s)
      Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 11681-11691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT12010

    • Author(s)
      Iwabu, M., Yamauchi, T., Okada-Iwabu, M., Sato, K., Nakagawa, T., Funata, M., Yamaguchi, M., Namiki, S., Nakayama, R., Tabata, M., Ogata, H., Kubota, N.,Takamoto, I., Hayashi, YK., Yamauchi, N., Waki, H., Fukayama, M., Nishino, I., Tokuyama, K., Ueki, K., Oike, Y., Ishii, S., Hirose, K., Shimizu, T., Touhara, K., and Kadowaki, T
    • Journal Title

      Nature

      Volume: 464 Issue: 7293 Pages: 1313-1319

    • DOI

      10.1038/nature08991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19002011, KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-21680035, KAKENHI-PROJECT-22790244
  • [Journal Article] Adiponectin and AdipoR1 regulate PGC1・and mitochondria by Ca^<2+> and AMPK/SIRT1.2010

    • Author(s)
      Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T
    • Journal Title

      Nature 464

      Pages: 1313-1319

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Adiponectin and AdipoR1 regulate PGC-lalpha and mitochondria by Ca(2+) and AMPK/SIRT1.2010

    • Author(s)
      Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T.
    • Journal Title

      Nature (published online Mar.31, 2010)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Dietary restriction; Standing up for sirtuins.2010

    • Author(s)
      Helfand, Imai S, Itoh H, Kadowaki T, Koya D, Leeuwenburgh C, Mcburney M, Nabeshima Y, Neri C, Oberdoerffer P, PestellRG, Rogina B, Sadoshima J, Sartorelli V, Serrano M, Sinclair DA, Steegborn C, Tatar M, Tissenbaum HA, Tong Q, Tsubota K, Vaquero A, Verdin E
    • Journal Title

      Science

      Volume: 329 Pages: 1012-1015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit2010

    • Author(s)
      Takeuchi Y, Kadowaki T
    • Journal Title

      J. Biol. Chem.

      Volume: 285 Pages: 11681-11691

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity2009

    • Author(s)
      Nishimura S, Hara K, Ueki K, Kadowaki T
    • Journal Title

      Nature Medicine

      Volume: 15 Issue: 8 Pages: 914-920

    • DOI

      10.1038/nm.1964

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-21390321
  • [Journal Article] Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 22009

    • Author(s)
      Assmann A, Kadowaki T
    • Journal Title

      Mol. Cell. Bio1.

      Volume: 29 Pages: 3219-3228

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity.2009

    • Author(s)
      Nishimura S, Manabe I, Naga, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R
    • Journal Title

      Nat. Med. 15(8)

      Pages: 914-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases expression of very low density lipoprotein receptor gene in adipocytes2009

    • Author(s)
      Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K and Kadowaki T
    • Journal Title

      J Biol Chem

      Volume: 284 Issue: 44 Pages: 30049-30057

    • DOI

      10.1074/jbc.m109.047993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390278
  • [Journal Article] Role of the liver in glucose homeostasis in P13-kinase p85{alpha}-deficient mice2009

    • Author(s)
      Aoki K, Kubota N, Kadowaki T
    • Journal Title

      Am. J. Physiol. Endocrinol. Metab

      Volume: 296 Issue: 4 Pages: E842-E853

    • DOI

      10.1152/ajpendo.90528.2008

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence2009

    • Author(s)
      Igarashi M, Kadowaki T
    • Journal Title

      J. Lipid Res

      Volume: 51 Issue: 2 Pages: 274-285

    • DOI

      10.1194/jlr.m900201-jlr200

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association.2009

    • Author(s)
      Miyake, K., Yasuda, K. (4番目), Osawa, H. (6番目), Makino, H. (32番目), Nanjo, K. (33), Kadowaki, T. (34), Kasuga, M. (35人中35番目), ほか28名
    • Journal Title

      J Hum Genet 54(4)

      Pages: 236-41

    • NAID

      10030730081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Critical role of class IA P13K for c-Rel expression in B lymphocytes2009

    • Author(s)
      Matsuda S, Kadowaki T
    • Journal Title

      Blood

      Volume: 113 Issue: 5 Pages: 1037-1044

    • DOI

      10.1182/blood-2008-06-163725

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Kulkarni RN : Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate-2.2009

    • Author(s)
      Assmann A, Ueki K, Winnay JN, Kadowaki T,
    • Journal Title

      Mol Cell Biol 29

      Pages: 3219-3228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.2009

    • Author(s)
      Awazawa M, Ueki K, Inabe K, Yamauchi T, Kanako K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T
    • Journal Title

      Biochem Biophys Res Commun 382

      Pages: 51-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Diabetes n Asia: epidemiology, risk factors, and pathophysiology2009

    • Author(s)
      Chan JC, Kadowaki T
    • Journal Title

      JAMA

      Volume: 301 Issue: 20 Pages: 2129-2140

    • DOI

      10.1001/jama.2009.726

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] The role of the liver in glucose homeostasis in PI 3-kinase p85{alpha}-deficient mice.2009

    • Author(s)
      Aoki K, Matsui J, Kubota N, Nakajima H, Iwamoto K, Takamoto I, Tsuji Y, Iwamoto K, Takamoto I, Tsuji Y, Ohno A, Mori S, Tokuyama K, Murakami K, asano T, Aizawa S, Tobe K, Kadowaki T, Terauchi Y
    • Journal Title

      Am J Physiol Endocrinol Metab 296

      Pages: 842-853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] The death effector domain-containing DEDD supports S6K1 activity via preventing Cdk1-dependent inhibitory phosphorylation2009

    • Author(s)
      Kurabe N, Arai S, Nishijima A, Kubota N, Suizu F, Mori M, Kurokawa J, Kondo-Miyazaki M, Ide T, Murakami K, Miyake K, Ueki K, Koga H, Yatomi Y, Tashiro F, Noguchi M, Kadowaki T, Miyazaki T.
    • Journal Title

      J Biol Chem 284

      Pages: 5050-5055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases the expression of very low density lipoprotein receptor gene in adipocytes.2009

    • Author(s)
      Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
    • Journal Title

      J Biol Chem 30

      Pages: 30049-30057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Rimonabant ameliorates insulin resistance vla both adiponectin-dependent and adiponectin-independent pathways.2009

    • Author(s)
      Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Yamauchi T, Noda T,Nagai R, Tcrauchi Y, Tobe K, Ueki K, Kadowaki T
    • Journal Title

      J. Biol. Chem 284

      Pages: 1803-1812

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] How controlling of hypertension might matter-Beyond blood pressure-2009

    • Author(s)
      Hara K, Kadowaki T
    • Journal Title

      Circulation J 73

      Pages: 2208-2209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Successful desensitization by glargine administration in patient with insulin allergy : a case report.2009

    • Author(s)
      Hara M, Izumida Y, Sato N, Ohashi K, Osuga JI, Tobe K, Tsukamoto K, Kadowaki T
    • Journal Title

      Diabetes Res Clin Pract 84

      Pages: 48-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Rimonabant amelio- rates insulin resistance via both adipo- nectin-dependent and adiponectin -independent pathways2009

    • Author(s)
      atanabe T, Kubota N, Iwabu M, Yamauchi T, Ueki K, Kadowaki T
    • Journal Title

      J.Biol.Chem.

      Volume: 284 Issue: 3 Pages: 1803-1812

    • DOI

      10.1074/jbc.m807120200

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Ablation of neutral cholesterol easter hydrolase 1 accelerates atherosclerosis2009

    • Author(s)
      Sekiya M, Kadowaki T
    • Journal Title

      Cell Metabolism

      Volume: 10 Issue: 3 Pages: 219-228

    • DOI

      10.1016/j.cmet.2009.08.004

    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21591123
  • [Journal Article] Effects of insulin glulisine sa mono- or add-on therapy in patients with type 2 diabetes mellitus.2009

    • Author(s)
      Kawamori R, Iwamoto Y, Kadowaki T, Iwasaki M, Kim SW, Woo JT, Baik SH, Yoon KH
    • Journal Title

      Diabetes Obes Metab 11

      Pages: 900-909

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Impact of small molecule glucokinase activator on glucose metabolism, and beta cell function and mass2009

    • Author(s)
      Nakamura A, Kubota N, Kadowaki T
    • Journal Title

      Endocrinology

      Volume: 150 Pages: 1147-1154

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Rimonabant ameliorates insulin resistance via both adiponectin-dependent and asiponectin-independent pathways2009

    • Author(s)
      Watanabe T, Kubota N, Ohsugi M, Kubota T, Takammoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Ymauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T
    • Journal Title

      J Biol Chem 284

      Pages: 1803-1812

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Impact of small-molecule glucokinase activator on glucose metabolism and beta-cell mass2009

    • Author(s)
      Nakamura A, Terauchi Y, Ohyama S, Kubota J, shimazaki H, Nambu T, Takamoto I, Kubota N, Eiki J, Yoshioka N, Kadowaki T, Koike T
    • Journal Title

      Endocrinology 150

      Pages: 1147-1154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Reconsideration of Insulin Signals Induced by Improved Laboratory Animal Diets, Japanese and American Diets, in IRS-2 Deficient Mice.2009

    • Author(s)
      Hashimoto H, Arai T, Hikishima K, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Okano H, Yamauchi T, Kubota N, Ueki K, Tobe K, Tamaoki N, Kadowaki T, Kosaka K
    • Journal Title

      Exp Clin Endocrinol Diabetes. 117(10)

      Pages: 577-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Journal Article] Alpha2-AMPK activity is not essential for an increase in fatty acid oxi- dation during low-intensity exercise2009

    • Author(s)
      Miura S, Kubota N, Kadowaki T, Ezaki O, et al.
    • Journal Title

      Am. J. Physiol. Endocrinol. Metab.

      Volume: 296 Issue: 1 Pages: E47-E55

    • DOI

      10.1152/ajpendo.90690.2008

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Efficacy and safety of insulin glulisine in Japanese patients with type l diadbetes mellitus.2009

    • Author(s)
      Kawamori R, Kadowaki T, Ishii H, Iwasaki M, Iwamoto Y
    • Journal Title

      Diabetes Obes Metab 11

      Pages: 891-899

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6, 244.2009

    • Author(s)
      Omori, S., Kadowaki, T. (10番目), ほか10名
    • Journal Title

      Japanese individuals. Diabetologia 52(8)

      Pages: 1554-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Neuronal IGF-1 resistance reduces Ab-accumulation and protects against premature death in a model of Alzheimer's disease2009

    • Author(s)
      Freude S, Kubota N, Kadowaki T
    • Journal Title

      FASEB J.

      Volume: 23 Issue: 10 Pages: 3315-3324

    • DOI

      10.1096/fj.09-132043

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] a2-AMPK activity is not essential for an increase in fatty acid oxidation during low-intensity exercise.2009

    • Author(s)
      Miura S,Kai Y,Kamei Y,Bruce CR, Kubota N, Febbraio MA,Kadowaki T, Ezaki O
    • Journal Title

      Am J Physiol Endocrinol Metab. 296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] The Death Effector Domain-containing DEDD Supports S6K1 Activity via Preventing Cdk1-dependent Inhibitory Phosphorylation.2009

    • Author(s)
      Kurabe N, Arai S, Nishijima A, Kubota N, Suizu F, Mori M, Kurokawa J, Kondo-Miyazaki M, Ide T, Murakami K, Miyake K, Ueki K, Koga H, Yatomi Y, Tashiro F, Noguchi M, Kadowaki T, Miyazaki T
    • Journal Title

      J Biol Chem 284

      Pages: 5050-5055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways.2009

    • Author(s)
      Watanabe T, Kubota N, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T
    • Journal Title

      J Biol Chem. 284(3)

      Pages: 1803-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases the expression of very low density lipoprotein receptor gene in adipocytes2009

    • Author(s)
      Takazawa T, Yamauchi T, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
    • Journal Title

      J. Biol. Chem.

      Volume: 284 Pages: 30049-30057

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Reconsideration of insulin signals induced by improved laboratory animal diets, Japanese and American diets, in IRS-2 deficcient mice.2009

    • Author(s)
      Hashimoto H, Arai T, Mori A, Kawai K, Hikishima K, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Okano H, Yamauchi T, Kubota N, Ueki K, Tobe K, Tamaoki N, Kadowaki T, Kosaka K
    • Journal Title

      Exp Clin Endocrinol Diabetes 117

      Pages: 577-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] The death effector domain-containing DEDD supports S6K1 activity via preventing Cdk1- dependent inhibitory phosphor- rylation2009

    • Author(s)
      Kurabe N, Kubota N, Kadowaki T
    • Journal Title

      J. Biol. Chem.

      Volume: 284 Pages: 5050-5055

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Replication study for the association of new meta-analysis-derived risk loci with sus- ceptibility to type 2 diabetes in 6,244 Japanese individuals2009

    • Author(s)
      Omori S, Kadowaki T
    • Journal Title

      Diabetologia

      Volume: 52 Issue: 8 Pages: 1554-1560

    • DOI

      10.1007/s00125-009-1397-5

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity.2009

    • Author(s)
      Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Ueki K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R
    • Journal Title

      Nat Med 15

      Pages: 914-920

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Dynamic Functional Relay between Insulin Receptor Substrate 1 and 2 in Hepatic Insulin Signaling during Fasting and Feeding2008

    • Author(s)
      Kubota N,Ueki K,Kadowaki T et al.
    • Journal Title

      Cell Metab 8

      Pages: 49-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] TamaokiN, Nomura T, Kosaka K. An Efficient reproductive method for Irs2-/- micewith C57BL/6JJcl genetic background2008

    • Author(s)
      Hashimoto H, Eto T, Kamisako T, Hoya N,Hatakeyama T, Arai T, Yokosuka M,Ohnishi Y, Ito M, Hioki K, Suzuki R,Ohsugi M, Saito M, Ueyama Y, YamauchiT, Kubota N, Tobe K, Kadowaki T.
    • Journal Title

      Exp. Anim. 57

      Pages: 407-411

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding2008

    • Author(s)
      Kubota N, Ueki K, Kadowaki T
    • Journal Title

      Cell Metabolism

      Volume: 8 Issue: 1 Pages: 49-64

    • DOI

      10.1016/j.cmet.2008.05.007

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS.2008

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N.
    • Journal Title

      FEBS Lett. 582

      Pages: 74-80

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance.2008

    • Author(s)
      Takamoto I, Terauchi Y, Kubota N, Ohsugi M, Ueki K, Kadowaki T
    • Journal Title

      Diabetes Obes Metab 10 Suppl 4

      Pages: 147-156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.2008

    • Author(s)
      Yasuda, K., Miyake, K., Osawa, H. (5番目), Makino, H. (44番目), Nanjo, K. (45), Kadowaki, T. (46), Kasuga, M. (47人中47番目), ほか40名
    • Journal Title

      Nature Genetics 40(9)

      Pages: 1092-1097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Molecular mechanismof moderate insulin resistance in adiponectin-knockout mice2008

    • Author(s)
      Yano W, Kubota N, Itoh S, Kubota T, Awazawa M, Moroi M, Sugi K, Takamoto I, Ogata H, Tokuyama K, Noda T, Terauchi Y, Ueki K, Kadowaki T.
    • Journal Title

      Endocr. J. 55

      Pages: 515-522

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] An Efficient Reproductive Method for Irs2(-/-) Mice with C57BL/6JJcl Genetic Background.2008

    • Author(s)
      Hashimoto H, Eto T, Kamisako T, Hoya N, Hatakeyama T, Arai T, Yokosuka M, Ohnishi Y, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Yamauchi T, Kubota N, Tobe K, Kadowaki T, Tamaoki N, Nomura T, Kosaka K
    • Journal Title

      Exp Anim. 57

      Pages: 407-11

    • NAID

      10024166620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Journal Article] The Death Effector Domain-containing DEDD Supports S6K1 Activity via Preventing Cdk1-dependent Inhibitory Phosphorylation2008

    • Author(s)
      Kurabe N, Kubota N, Ueki K,Kadowaki T et al.
    • Journal Title

      J Biol Chem 284

      Pages: 5050-5055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations2008

    • Author(s)
      Unoki H, Hara K, Kadowaki T
    • Journal Title

      Nature Genetics

      Volume: 40 Issue: 9 Pages: 1098-1102

    • DOI

      10.1038/ng.208

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Fulminant type 1 diabetes mellitus observed in insulin receptor substrate 2 deficient mice2008

    • Author(s)
      Arai T, Hashimoto H, Kawai K, Mori A, Ohnishi Y, Hioki K, Ito M, Sito M, Ueyama Y, Ohsugi M, Suzuki R, Kubota N, Yamauchi T, Tobe K, Kadowaki T, Kosaka K
    • Journal Title

      Clin Exp Med 8

      Pages: 93-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding2008

    • Author(s)
      Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Ngai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T
    • Journal Title

      Cell Metab 8

      Pages: 49-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Dynamic Functional Relay between Insulin Receptor Substrate 1 and 2 in Hepatic Insuin Signaling during Fasting and Feeding.2008

    • Author(s)
      Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Kadowaki T
    • Journal Title

      Cell Metab 8

      Pages: 49-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta.2008

    • Author(s)
      Oishi Y, Manabe I, Tobe K, Ohsugi M, Kubota T, Fujiu K, Maemura K, Kubota N, Kadowaki T, Nagai R
    • Journal Title

      Nat Med. 14(6)

      Pages: 656-66

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration2008

    • Author(s)
      Okamoto M, Kubota N, Kadowaki T
    • Journal Title

      Diabetologia

      Volume: 51 Issue: 5 Pages: 827-835

    • DOI

      10.1007/s00125-008-0944-9

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Thephysiological and pathophysiologicalrole of adiponectin and adiponectinreceptors in the peripheral tissues and CNS2008

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N.
    • Journal Title

      FEBS Lett. 582

      Pages: 74-80

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration.2008

    • Author(s)
      Okamoto M, Ohara-Imaizumi M, Kubota N, Hashimoto S, Eto K, Kanno T, Kubota T, Wakui M, Nagai R, Noda M, Nagamatsu S, Kadowaki T
    • Journal Title

      Diabetologia 51

      Pages: 827-835

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Impact of increased PPARγ; activity in adipocytes in vivo on adiposity, insulin sensitivity and the effects of rosiglita zone treatment.2008

    • Author(s)
      Takasawa K, Kubota N, Terauchi Y, Kadowaki T
    • Journal Title

      Endocrine J 55

      Pages: 767-776

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Impact of IncreasedPPARgamma Activity in Adipocytes invivo on Adiposity, Insulin Sensitivityand the Effects of RosiglitazoneTreatment2008

    • Author(s)
      Takasawa K, Kubota N, Terauchi Y, Kadowaki T.
    • Journal Title

      Endocr. J 55

      Pages: 767-776

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses colonic epithelial cell turnover and colon carcinogenesis through inhibition of the beta-catein/T cell factor (TCF) pathway.2008

    • Author(s)
      Fujisawa T, Nkajima A, Fujisawa N, Tkahashi H, Ikeda I, Tomimoto A, Yonemitsu K, Nkajima N, Kudo C, Wada K, Kubota N, Terauchi Y, Kadowaki T, Nkagama H, Blumberg RS
    • Journal Title

      J Pharmacol Sci 106

      Pages: 627-638

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS2008

    • Author(s)
      Kadowaki T, Yamauchi T, Kuhota N.
    • Journal Title

      FEBS Lett 582

      Pages: 74-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition2008

    • Author(s)
      Fujisawa T, Kubota N, Yamauchi T, Kadowaki T
    • Journal Title

      Gut

      Volume: 57 Issue: 11 Pages: 1531-1538

    • DOI

      10.1136/gut.2008.159293

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Dynamic Functional Relay between Insulin Receptor Substrate 1 and 2 in Hepatic Insulin Signaling during Fasting and Feeding.2008

    • Author(s)
      Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T
    • Journal Title

      Cell Metab 8

      Pages: 49-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] An effecient reproductive method for Irs2-/- mice with C57BL/6JJcl genetic background2008

    • Author(s)
      Hashimoto H, Eto T, Kamisako t, Hoya N, Hatakeyama T, Arai T, Yokosuka M, Ohnishi Y, Ito M, Hioki K, Suzuki R, Osugi M, Saito M, Ueyama Y, Ymauchi T, Kubota N, Tobe K, Kadowaki T, Tamaoki N, Nomura T, Kosaka K.
    • Journal Title

      Exp Anim 57

      Pages: 407-411

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition2008

    • Author(s)
      Fujisawa T, Endo H, Tomimoto A, Sugiyama M, Takahashi H, Saito S, Inamori M,nakajima N, Watanabe M, Kubota N, Yamauchi T, Kadowaki T, Wada K, Nakagama H, Nakajima A.
    • Journal Title

      Gut 57

      Pages: 1531-1538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Dynamic functional relay between insulin receptorsubstrate 1 and 2 in hepatic insulinsignaling during fasting and feeding2008

    • Author(s)
      Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, OgataH, Tokuyama K, Ohsugi M, Sasako T, MoroiM, Sugi K, Kakuta S, Iwakura Y, Noda T,Ohnishi S, Nagai R, Tobe K, Terauchi Y,Ueki K, Kadowaki T.
    • Journal Title

      Cell Metab. 8

      Pages: 49-64

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta.2008

    • Author(s)
      Oishi Y, Manabe I, Tobe K, Ohsugi M, Kubota T, Fujiu K, Maemura K, Kubota N, Kadowaki T, Nagai R
    • Journal Title

      Nat Med 14

      Pages: 656-666

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue2008

    • Author(s)
      Nishimura S, Kadowaki T
    • Journal Title

      J.Clin.Invest.

      Volume: 118 Pages: 710-721

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008

    • Author(s)
      Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T
    • Journal Title

      Cell Metabolism 8

      Pages: 49-64

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Crucial role of IRS-2 in compensatory B-cell hyperplasia in response to high-fat-diet-induced insulin resistance.2008

    • Author(s)
      Takamoto I, Terauchi Y, Kubota N, Kubota T. Ohsugi M, Ueki K, Kadowaki T
    • Journal Title

      Diabetes, Obesity and Metabolism 10

      Pages: 147-156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance2008

    • Author(s)
      Takamoto I, terauchi Y, Kubota N, Ohsugi M, ueki K, Kadowaki T
    • Journal Title

      Diabetes Obes Metab 10

      Pages: 147-156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.2008

    • Author(s)
      Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T
    • Journal Title

      Cell Metab. 8(1)

      Pages: 49-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Journal Article] The physiological and pathophysiological role of adiponectin and adipone ctin receptors in the peripheral tissues and CNS.2008

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N.
    • Journal Title

      FEBS Lett. 582

      Pages: 74-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Impact of increased PPARgamma activity in adipocytes in vivo on adiposity, insulin sensitivity and the effects of rosiglitazone treatment2008

    • Author(s)
      Takasawa K, Kubota N, Terauchi Y, Kadowaki T.
    • Journal Title

      Endocr J 55

      Pages: 767-776

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] SUMOylation ofKruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta2008

    • Author(s)
      Oishi Y, Manabe I, Tobe K, Ohsugi M, Kubota T, Fujiu K, Maemura K, KUbota N, Kadowaki T, Nagai R
    • Journal Title

      Nat Med 14

      Pages: 656-666

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance2008

    • Author(s)
      Takamoto I, Kubota N, Ueki K,Kadowaki T et al.
    • Journal Title

      Diabetes Obes Metab 10 Suppl 4

      Pages: 147-156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] Adiponectin Suppresses Colorectal Carcinogenesis under the High-fat Diet Condition.2008

    • Author(s)
      Fujisawa T, Endo H, Tomimoto A, Sugiyama M, Takahashi H, Saito S, Inamori M, Nakajima N, Watanabe M, Kubota N, Yamauchi T, Kadowaki T, Wada K, Nakagame H, Nakajima A
    • Journal Title

      Gut 57

      Pages: 1531-1538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Adiponectin induces insulinsecretion in vitro and in vivo at a lowglucose concentration.2008

    • Author(s)
      Okamoto M, Ohara-Imaizumi M, Kubota N, Hashimoto S, Eto K, Kanno T, Kubota T,Wakui M, Nagai R, Noda M, Nagamatsu S,Kadowaki T
    • Journal Title

      Diabetologia 51

      Pages: 827-835

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Peroxisomeproliferator-activated receptor gamma(PPARgamma) suppresses colonic epithelial cell turnover and coloncarcinogenesis through inhibition ofthe beta-catenin/T cell factor (TCF)pathway2008

    • Author(s)
      Fujisawa T, Nakajima A, Fujisawa N, Takahashi H, Ikeda I, Tomimoto A,Yonemitsu K, Nakajima N, Kudo C, Wada K, Kubota N, Terauchi Y, Kadowaki T, Nakagama H, Blumberg RS
    • Journal Title

      J. Pharmacol. Sci. 106

      Pages: 627-638

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue2008

    • Author(s)
      Nishimura S, Manabe I, Nagasaki M, Seo K, Yamashita H, Hosoya Y, Ohsugi M, Tobe K, Kadowaki T, Nagai R, Sugiura S.
    • Journal Title

      J Clin Invest 118(2)

      Pages: 710-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages2008

    • Author(s)
      Okazaki H, Kadowaki T
    • Journal Title

      J.Biol. Chem.

      Volume: 283 Issue: 48 Pages: 33357-33364

    • DOI

      10.1074/jbc.m802686200

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance.2008

    • Author(s)
      Takamoto I, Terauchi Y, Kubota N, Ohsugi M, Ueki K, Kadowaki T
    • Journal Title

      Diabetes Obes Metab. 10(Suppl 4)

      Pages: 147-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Journal Article] 5-Hydroxytryptamine 2A receptor signaling cascade modulates adiponectin and plasminogen activator inhibitor 1 expression in adipose tissue.2008

    • Author(s)
      Uchida-Kitajima S, Ymauchi T, Takashina Y,Okada-Iwabu M, Iwabu M, Ueki K,Kadowaki T
    • Journal Title

      FEBS Lett 582

      Pages: 3037-3044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] The pathophysiological roles of COX-1 and COX-2 in the intestinal smooth muscle contractility under the anaphylactic condition.2008

    • Author(s)
      Kadowaki H
    • Journal Title

      Biomedical Research 29

      Pages: 113-117

    • NAID

      130004724049

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590507
  • [Journal Article] Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4, 087 Japanese subjects.2008

    • Author(s)
      Miyake, K., Yasuda, K. (4番目), Osawa, H. (5番目), Makino, H. (20番目), Nanjo, K. (21), Kadowaki, T. (22), Kasuga, M. (23人中23番目), ほか16名
    • Journal Title

      J Hum Genet 53(2)

      Pages: 174-180

    • NAID

      10021248002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] The physiological and pathophysiological role of adiponectin and adiponectin receptoiCs in the peripheral tissues and CNS2008

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N.
    • Journal Title

      FEBS Lett 582

      Pages: 74-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Crucial role ofinsulin receptor substrate-2 incompensatory beta-cell hyperplasia inresponse to high fat diet-inducedinsulin resistance2008

    • Author(s)
      Takamoto I, Terauchi Y, Kubota N, OhsugiM, Ueki K, Kadowaki T.
    • Journal Title

      Diabetes Obes. Metab. S4

      Pages: 147-156

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] AdiponectinSuppresses Colorectal Carcinogenesis under the High-fat Diet Condition2008

    • Author(s)
      Fujisawa T, Endo H, Tomimoto A, SugiyamaM, Takahashi H, Saito S, Inamori M,Nakajima N, Watanabe M, Kubota N,Yamauchi T, Kadowaki T, Wada K,Nakagama H, Nakajima A.
    • Journal Title

      Gut 57

      Pages: 1531-1538

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Molecular Mechanism of Moderate Insulin Resistance in Adiponectin-Knockout Mice.2008

    • Author(s)
      Yano W, Kubota N, Itoh S, Kubota T, Awazawa M, Moroi M, Sugi K, Takamoto I, Ogata H, Tokuyama K, Noda T, Terauchi Y, Ueki K, Kadowaki T
    • Journal Title

      Endocr J 55

      Pages: 515-522

    • NAID

      10021266439

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] An Efficient reproductive method for Irs2-/- mice with C57BL /6 Jcl genetic background.2008

    • Author(s)
      Hashimoto H, Eto T, Kamisako T, Hoya N, Hatakeyama T, Arai T, Yokosuka M, Ohnishi Y, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Yamauchi T, Kubota N, Tobe K, Kadowaki T, Tamaoki N, Nomura T
    • Journal Title

      Exp. Anim. 57

      Pages: 407-411

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta.2008

    • Author(s)
      Oishi Y, Kubota N, Kadowaki T
    • Journal Title

      Nature Medicine

      Volume: 14 Issue: 6 Pages: 656-666

    • DOI

      10.1038/nm1756

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] Fulminant type 1 diabetes mellitus observed in insulin receptor substrate 2 deficient mice.2008

    • Author(s)
      Arai T, Hashimoto H, Kawai K, Mori A, Ohnishi Y, Hioki K, Ito M, Saito M, Ueyama Y, Ohsugi M, Suzuki R, Kubota N, Yamauchi T, Tobe K, Kadowaki T, Kosaka K
    • Journal Title

      Clin Exp Med. 8

      Pages: 93-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Journal Article] The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS2008

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N.
    • Journal Title

      FEBS Lett. 582

      Pages: 74-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus2008

    • Author(s)
      Yasuda K, Hara K, Kadowaki T
    • Journal Title

      Nature Genetics

      Volume: 40 Issue: 9 Pages: 1092-1097

    • DOI

      10.1038/ng.207

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Journal Article] The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS.2008

    • Author(s)
      Kadowaki T, et. al.
    • Journal Title

      FEBS Lett. 582

      Pages: 74-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] The pathophysiological roles of COX-1 and COX-2 in the intestinal smooth muscle contractility under the anaphylactic condition2008

    • Author(s)
      Kadowaki H
    • Journal Title

      Biomedical Research (掲載確定)

    • NAID

      130004724049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590507
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim 56

      Pages: 149-154

    • NAID

      130000068045

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007

    • Author(s)
      Yamauchi T, Kubota N, Kadowaki T.
    • Journal Title

      Nature Medicine 13(3)

      Pages: 332-339

    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] 「標準的な健診・保健指導プログラム」の背景と概略2007

    • Author(s)
      門脇 孝
    • Journal Title

      血圧 14・2

      Pages: 163-168

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390578
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
    • Journal Title

      Cell Metab. 6

      Pages: 55-68

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M. Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim 56(2)

      Pages: 149-54

    • NAID

      130000068045

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
    • Journal Title

      Cell Metab. 6

      Pages: 55-68

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim. 56

      Pages: 149-154

    • NAID

      130000068045

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] The back ground and overview " Standardization of health examination survey and educational program2007

    • Author(s)
      Takashi Kadowaki
    • Journal Title

      Blood Pressure 14(2)

      Pages: 163-168

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390578
  • [Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007

    • Author(s)
      Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K,Tobe K,Nagai R,Ueki K,Kadowaki T.
    • Journal Title

      Nat Med. 13

      Pages: 332-339

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.2007

    • Author(s)
      Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
    • Journal Title

      Cancer Sci. 98

      Pages: 1120-1127

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoRl and AdipoR22007

    • Author(s)
      Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
    • Journal Title

      Cancer Sci. 98

      Pages: 1120-1127

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Mimokoshi Y, Ueki K,Minokoshi Y,Kadowaki T.
    • Journal Title

      CeU Metab 6

      Pages: 55-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.2007

    • Author(s)
      Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
    • Journal Title

      Cancer Sci. 98

      Pages: 1120-1127

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.2007

    • Author(s)
      Horikoshi M, Hara K, Ito C, Shojima N, Nagai R, Ueki K, Froguel P, Kadowaki T
    • Journal Title

      Diabetologia 50

      Pages: 2461-2466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR22007

    • Author(s)
      Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
    • Journal Title

      Cancer Sci. 98

      Pages: 1120-1127

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Improved ELISA for selectivemeasurement of adiponectin multimersand identification of adiponectin inhuman cerebrospinal fluid.2007

    • Author(s)
      Ebinuma H, Miida T, Yamauchi T, HadaY, Hara K, Kubota N, Kadowaki T.
    • Journal Title

      Clin. Chem 53

      Pages: 1541-1544

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid2007

    • Author(s)
      Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
    • Journal Title

      Clin Chem. 53

      Pages: 1541-1544

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007

    • Author(s)
      Yamauchi T, Kubota N, Kadowaki T.
    • Journal Title

      Nature Medicine 13(3)

      Pages: 332-339

    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid.2007

    • Author(s)
      Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
    • Journal Title

      Clin Chem. 53

      Pages: 1541-1544

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR22007

    • Author(s)
      Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
    • Journal Title

      Cancer Sci. 98

      Pages: 1120-1127

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Frequency of the G/G genotype of resistin single nucleotide polymorphism at -420 appears to be increased in younger-onset type 2 diabetes.2007

    • Author(s)
      Ochi, M., Osawa, H., Kadowaki, T. (13番目), Kasuga, M. (15番目), Makino, H. (16人中16番目), ほか11名
    • Journal Title

      Diabetes 56

      Pages: 2834-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim 56

      Pages: 149-154

    • NAID

      130000068045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Improved EHSA for selective measmement of adiponectin multimers and identification of adipollectin in human cerebrospinal fluid2007

    • Author(s)
      Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
    • Journal Title

      Clin Chem 53

      Pages: 1541-1544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.2007

    • Author(s)
      Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
    • Journal Title

      Cancer Sci. 98

      Pages: 1120-1127

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007

    • Author(s)
      Hashmoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim 56

      Pages: 149-154

    • NAID

      130000068045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid2007

    • Author(s)
      Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
    • Journal Title

      Clin Chem. 53

      Pages: 1541-1544

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007

    • Author(s)
      窪田 直人、植木 浩二郎、門脇 孝, 他
    • Journal Title

      Cell Metabolism 6

      Pages: 55-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable. Exp Anim. 56 : 149-154, 20072007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim. 56

      Pages: 149-154

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Targeted disruption ofAdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions2007

    • Author(s)
      Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
    • Journal Title

      Nat Med. 13

      Pages: 322-339

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoRI and AdipoR22007

    • Author(s)
      Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
    • Journal Title

      Cancer Sci 98

      Pages: 1120-1127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population2007

    • Author(s)
      堀越 桃子、植木 浩二郎、門脇 孝, 他
    • Journal Title

      Diabetologia 50

      Pages: 2461-2466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.2007

    • Author(s)
      Horikoshi, M., Kadowaki, T. (7人中7番目)
    • Journal Title

      Diabetologia 50(12)

      Pages: 2461-2466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Improved EHSA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid2007

    • Author(s)
      Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
    • Journal Title

      Clin Chem 53

      Pages: 1541-1544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Selective purification and characterization of adiponectin multimer species from human pasma.2007

    • Author(s)
      Hada Y, Yamauchi T, Waki H, Tsuchida A, Hara K, Yago H, Miyazaki O, Ebinuma H, Kadowaki T.
    • Journal Title

      Biochem Biophys Res Commun. 356(2)

      Pages: 487-493

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y,Kadowaki,T
    • Journal Title

      Cell Metab. 6

      Pages: 55-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T
    • Journal Title

      Cell Metab 6

      Pages: 55-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid.2007

    • Author(s)
      Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
    • Journal Title

      Clin Chem. 53

      Pages: 1541-1544

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Targeted disruption of AdipoRl and AdipoR2 causes abrogation of adiponectin binding and metabohc actions2007

    • Author(s)
      Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tbkuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
    • Journal Title

      Nat Med 13

      Pages: 332-339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      PLoS ONE 2(10)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390410
  • [Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specfic membrane receptors Adipol and AdipoR22007

    • Author(s)
      Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
    • Journal Title

      Cancer Sci 98

      Pages: 1120-1127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels2007

    • Author(s)
      Nishimura S, Manabe I, Nagasaki M, Hosoya Y, Yamashita H, Fujita H, Ohsugi M, Tobe K, Kadowaki T, Nagai R, Sugiura S.
    • Journal Title

      Diabetes 56(6)

      Pages: 1517-26

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid.2007

    • Author(s)
      Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
    • Journal Title

      Clin Chem. 53

      Pages: 1541-1544

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Targeted disruption of AdipoR1 and Adipo2 causes abrogation of adiponectin binding and metabolic actions.2007

    • Author(s)
      Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
    • Journal Title

      Nat Med. 13(3)

      Pages: 332-339

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Targeted disruption of AdipoRl and AdipoR2 causes abrogation of adiponectin binding and metabolic actions2007

    • Author(s)
      Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
    • Journal Title

      Nat Med. 13

      Pages: 332-339

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007

    • Author(s)
      Yamauchi T, Kubota N, Kadowaki T.
    • Journal Title

      Nature Medicine 13(3)

      Pages: 332-339

    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable.2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim. 56

      Pages: 149-154

    • NAID

      130000068045

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid2007

    • Author(s)
      Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
    • Journal Title

      Clim Chem 53

      Pages: 1541-1544

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
    • Journal Title

      Cell Metab. 6

      Pages: 55-68

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
    • Journal Title

      Cell Metab 6

      Pages: 55-68

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Glucokinase and IRS-2 are required for compensatory β cell hyperplasia in response to high-fat diet-induced insulin resistance.2007

    • Author(s)
      Terauchi Y, Takamoto I, Kubota N, Matsui J, Suzuki R, Komeda K, Hara A, toyoda Y, Miwa I, Aizawa S, Tsutsumi S, Tsubamoto Y, Hashimoto S, Eto K, Nakamura A, Noda M, Tobe K, Aburatani H, Nagai R, Kadowaki T.
    • Journal Title

      J Clin Invest. 117(1)

      Pages: 246-257

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Role of alteredrenal lipid metabolism in thedevelopment of renal injury induced bya high-fat diet2007

    • Author(s)
      Kume S, Uzu T, Araki S, Sugimoto T,Isshiki K, Chin-Kanasaki M, Sakaguchi M,Kubota N, Terauchi Y, Kadowaki T, HanedaM, Kashiwagi A, Koya D
    • Journal Title

      J. Am. Soc. Nephrol 18

      Pages: 2715-2723

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Adiponectin stmulates AMP-activated protein kinase in the hypothalam us and increases food intake2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y,Kadowaki T.
    • Journal Title

      Cell Metab 6

      Pages: 55-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable.2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim. 56

      Pages: 149-154

    • NAID

      130000068045

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Adiponectin Stimulates AMP-ActivatedProtein Kinase in the Hypothalamus andIncreases Food Intake.2007

    • Author(s)
      Kubota N, Yano W, Kubota T, YamauchiT, Itoh S, Kumagai H, Kozono H, TakamotoI, Okamoto S, Shiuchi T, Suzuki R, SatohH, Tsuchida A, Moroi M, Sugi K, Noda T,Ebinuma H, Ueta Y, Kondo T, Araki E,Ezaki O, Nagai R, Tobe K, Terauchi Y,Ueki K, Minokoshi Y, Kadowaki T
    • Journal Title

      Cell Metab 6

      Pages: 55-68

    • Data Source
      KAKENHI-PROJECT-19591037
  • [Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007

    • Author(s)
      Yamauchi T, Kubota N, Kadowaki T
    • Journal Title

      Nature Medicine 13(3)

      Pages: 332-339

    • Data Source
      KAKENHI-PROJECT-18659265
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable.2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim. 56

      Pages: 149-154

    • NAID

      130000068045

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technologyare stable.2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim. 56

      Pages: 149-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population.2007

    • Author(s)
      Horikoshi, M., Kadowaki, T. (6人中6番目), ほか4名
    • Journal Title

      Diabetologia 50

      Pages: 747-751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] Adiponectin stimulates AMP- activated protein kinase in the hypothalamus and increases food intake2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, MoroiM, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki o, Nagai R, Tobe K, Terauchi Y Ueki K, Minokoshi Y Kadowaki T.
    • Journal Title

      Cell Metab. 6

      Pages: 55-68

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] 「標準的な健診・保健指導プログラム」の背景と概要2007

    • Author(s)
      門脇 孝
    • Journal Title

      血圧 14・2

      Pages: 163-168

    • Data Source
      KAKENHI-PROJECT-17390578
  • [Journal Article] 2型糖尿病患者とその血縁者の発症リスクの認知と予防行動実行の実態-2型糖尿病患者の血縁者に対する発症予防プルグラムの為の基礎調査-2006

    • Author(s)
      西垣昌和, 小林康司, 柴山大賀, 門脇孝, 数間恵子
    • Journal Title

      第11回日本糖尿病教育・看護学会学術集会

      Pages: 228-228

    • Data Source
      KAKENHI-PROJECT-16209064
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, et al.
    • Journal Title

      J. Clin. Invest. 116

      Pages: 1784-1792

    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, et al.
    • Journal Title

      J. Clin. Invest. 116

      Pages: 1784-1792

    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] The pathophysiological roles of COX-1 and COX-2 in the intestinal smooth muscle contractility under the anaphylactic condition2006

    • Author(s)
      Kadowaki, H
    • Journal Title

      Biomedical Research 29

      Pages: 113-117

    • NAID

      130004724049

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590507
  • [Journal Article] Attitude of Diabetes Care Specialists to Prevention of Diabetes to Relatives of Patients with Type 2 Diabetes2006

    • Author(s)
      Nishigaki M, Kobayashi K, T Shibayama, Kadowaki T, Kazuma K
    • Journal Title

      Journal of the Japan Diabetes Society. 49(8)

      Pages: 669-676

    • NAID

      10018570506

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209064
  • [Journal Article] Adiponectin-dependent and - independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinedions.2006

    • Author(s)
      Kubota N, Yamauchi T, Tobe K, Kadowaki T.
    • Journal Title

      Diabetes. 55 Suppl 2

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Association of Hepatocyte Nuclear Factor-4αP2 Promoter Haplotypes With Type 2 Diabetes in the Japanese Population.2006

    • Author(s)
      Hara K, Horikoshi M, Kitazato H, Ito C, Noda M, Ohashi J, Tokunaga K, Nagai R, Kadowaki T.
    • Journal Title

      Diabetes (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 26602-26614

    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, et al.
    • Journal Title

      J. Clin. Invest. 116

      Pages: 1784-1792

    • Data Source
      KAKENHI-PROJECT-18659265
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, et al.
    • Journal Title

      J. Clin. Invest. 116

      Pages: 1784-1792

    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 26602-26614

    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      J Clin Invest 116(7)

      Pages: 1784-1792

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones2006

    • Author(s)
      Kubota N, Yamauchi T, Tobe K, Kadowaki, T
    • Journal Title

      Diabetes 55

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006

    • Author(s)
      Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T.
    • Journal Title

      Diabetes Care 29

      Pages: 1357-1362

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T
    • Journal Title

      J. Biol. Chem. 281

      Pages: 26602-26614

    • Data Source
      KAKENHI-PROJECT-18659265
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T et al.
    • Journal Title

      J Clin Invest. 116

      Pages: 1784-1792

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390261
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
    • Journal Title

      J Clin Invest. 116(7)

      Pages: 1784-1792

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006

    • Author(s)
      Hara T, Yamauchi T, Kadowaki T.
    • Journal Title

      Diabetes Care 29

      Pages: 1357-1362

    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways2006

    • Author(s)
      Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 8748-8755

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Association of Hepatocyte Nuclear Factor-4a P2 Promoter Haplotypes With Type 2 Diabetes in the Japanese Population.2006

    • Author(s)
      Hara K, Horikoshi M, Kitazato H, Ito C, Noda M, Ohashi J, Tokunaga K, Nagai R, Kadowaki T.
    • Journal Title

      Diabetes (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      J Clin Invest. 116

      Pages: 1784-1792

    • Data Source
      KAKENHI-PROJECT-17390261
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
    • Journal Title

      J. Clin. Invest. 116

      Pages: 1784-1792

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Association of Hepatocyte Nuclear Factor-4αP2 Promoter Haplotypes With Type 2 Diabetes in the Japanese Population.2006

    • Author(s)
      Hara, K., Kadowaki, T. (11人中11番目), ほか9名
    • Journal Title

      Diabetes 55

      Pages: 1260-1264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] A polymorphism in the AMPKα2 subunit gene is associated with insulin resistance and type 2 diabetes in Japanese.2006

    • Author(s)
      Horikoshi, M., Miyake, K. (4番目), Kasuga, M. (7番目), Kadowaki, T. (9人中9番目), ほか5名
    • Journal Title

      Diabetes 55

      Pages: 919-923

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Journal Article] A polymorphism in the AMPKα2 subunit gene is associated with insulin resistance and type 2 diabetes in Japanese.2006

    • Author(s)
      Horikoshi M, Hara K, Ohashi J, Miyake K, Ito C, Kasuga M, Nagai R, Kadowaki T.
    • Journal Title

      Diabetes (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem 281

      Pages: 26602-26614

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Measurement of the high-molecular-weight form of adiponectin in plasmais useful for the prediction of insulih resistance and metabolic syndrome.2006

    • Author(s)
      Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T.
    • Journal Title

      Diabetes Care 29

      Pages: 1357-1362

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adiponectin-dependent and independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006

    • Author(s)
      Kubota N, Yamauchi T, Tobe K, Kadowaki, T
    • Journal Title

      Diabetes 55 Suppl 2

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006

    • Author(s)
      Hara T, Yamauchi T, Kadowaki T
    • Journal Title

      Diabetes Care 29

      Pages: 1357-1362

    • Data Source
      KAKENHI-PROJECT-18659265
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006

    • Author(s)
      Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Is hikawa M, Moroi M, Sugi K, Ya mauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 8748-8755

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T.
    • Journal Title

      Diabetes 55 Suppl 2

    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] A polymorphism in the AMPKα2 subunit gene is associated with insulin resistance and type 2 diabetes in Japanese.2006

    • Author(s)
      Horikoshi M, Hara K, Ohashi J, Miyake K, Ito C, Kasuga M, Nagai R, Kadowaki T.
    • Journal Title

      Diabetes (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Measurement of the high-molecular-weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome2006

    • Author(s)
      Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T.
    • Journal Title

      Diabetes Care 29

      Pages: 1357-1362

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T
    • Journal Title

      Diabetes 55 Suppl 2

    • Data Source
      KAKENHI-PROJECT-18659265
  • [Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006

    • Author(s)
      Hara T, Yamauchi T, Kadowaki T.
    • Journal Title

      Diabetes Care 29

      Pages: 1357-1362

    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin-dependent and-independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones2006

    • Author(s)
      Kubota N, Yamauchi T, Tobe K, Kadowaki, T.
    • Journal Title

      Diabetes 55

      Pages: 32-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006

    • Author(s)
      ・Kubota N, Yamauchi T, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 26602-26614

    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
    • Journal Title

      J Biol Chem. 281(36)

      Pages: 26602-26614

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006

    • Author(s)
      Hara T, Yamauchi T, Kadowaki T.
    • Journal Title

      Diabetes Care 29

      Pages: 1357-1362

    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 8748-8755

    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] 2型糖尿病患者の血縁者の発症予防に関する糖尿病医療専門職の意識2006

    • Author(s)
      西垣昌和, 小林康司, 柴山大賀, 門脇孝, 数間恵子
    • Journal Title

      糖尿病 in press

    • NAID

      10018570506

    • Data Source
      KAKENHI-PROJECT-16209064
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
    • Journal Title

      J.Biol. Chem. 281

      Pages: 26602-26614

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T
    • Journal Title

      J. Biol. Chem 281

      Pages: 26602-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BLJ6J : Jcl mice deficient in insulin receptor substrate 22006

    • Author(s)
      Hashimoto H, Arai T, Takeguchi A, Hioki K, Ohnishi Y, Kawai K, Ito M, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Comp Med 56(3)

      Pages: 176-87

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T.
    • Journal Title

      Diabetes 55 Suppl 2

    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 8748-8755

    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and-independent Pathways.2006

    • Author(s)
      Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, lshikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
    • Journal Title

      J.Biol. Chem. 281

      Pages: 8748-8755

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] 2型糖尿病患者の血縁者の発症予防に関する糖尿病医療専門職の意識2006

    • Author(s)
      西垣昌和, 小林康司, 柴山大賀, 門脇孝, 数間恵子
    • Journal Title

      糖尿病 49・8

      Pages: 669-676

    • NAID

      10018570506

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209064
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 8748-8755

    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006

    • Author(s)
      Kubota N, Yamauchi T, Kadowaki T
    • Journal Title

      J. Biol. Chem. 281

      Pages: 8748-8755

    • Data Source
      KAKENHI-PROJECT-18659265
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 26602-26614

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes,and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
    • Journal Title

      J.Clin. Invest. 116

      Pages: 1784-1792

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
    • Journal Title

      J. Clin. Invest 116

      Pages: 1784-1792

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by-Both Adiponectin-dependent and-independent Pathways2006

    • Author(s)
      Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem 281

      Pages: 8748-8755

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin-dependent and-independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006

    • Author(s)
      Kubota N, Yamauchi T, Tobe K, Kadowaki, T
    • Journal Title

      Diabetes 55 Suppl2

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome2006

    • Author(s)
      Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T.
    • Journal Title

      Diabetes Care 29

      Pages: 1357-1362

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
    • Journal Title

      J. Clin. Invest. 116

      Pages: 1784-1792

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006

    • Author(s)
      Kubota N, Yamauchi T, ・Kadowaki T.
    • Journal Title

      Diabetes 55 Suppl 2

    • Data Source
      KAKENHI-PROJECT-18390270
  • [Journal Article] 2型糖尿病患者の血縁者の発症予防に関する糖尿病医療専門職の意識2005

    • Author(s)
      西垣昌和, 小林康司, 柴山大賀, 門脇孝, 数間恵子
    • Journal Title

      第10回日本糖尿病教育・看護学会学術集会 9月

      Pages: 225-225

    • NAID

      10018570506

    • Data Source
      KAKENHI-PROJECT-16209064
  • [Journal Article] Adiponectin and adiponectin receptors.2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr.Review 26(3)

      Pages: 439-455

    • Data Source
      KAKENHI-PROJECT-17659276
  • [Journal Article] Role of Kruppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis.2005

    • Author(s)
      Mori T, Sakaue H, Iguchi H, Gomi H, Okada Y, Takashima Y, Nakamura K, Nakamura T, Yamauchi T, Kubota N, Kadowaki T, Matsuki Y, Ogawa W, Hiramatsu R, Kasuga M.
    • Journal Title

      J. Biol. Chem. 280

      Pages: 12867-12875

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Protective Role of Imatinib in Atherosclerosis.2005

    • Author(s)
      Kadowaki T, Kubota N.
    • Journal Title

      Arteriosclerosis, Thrombosis and Vascular Biology 24

      Pages: 801-803

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Adiponectin and adiponectin receptors2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr Rev 26(3)

      Pages: 439-451

    • Data Source
      KAKENHI-PROJECT-17659274
  • [Journal Article] Adiponectin and adiponectin receptors2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr Rev 26(3):

      Pages: 439-451

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Expression of DGAT2 in White Adipose Tissue Is Regulated by Central Leptin Action2005

    • Author(s)
      Suzuki R, Tobe K, Aoyama M, Sakamoto K, Ohsugi M, Kamei N, Nemoto S, Inoue A, Ito Y, Uchida S, Hara K, Yamauchi T, Kubota N, Terauchi Y, Kadowaki T
    • Journal Title

      J Biol Chem 280・5

      Pages: 3331-3337

    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Adiponectin and adiponectin receptors.2005

    • Author(s)
      Kadowaki T, Yamauchi T.
    • Journal Title

      26

      Pages: 439-51

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.2005

    • Author(s)
      Hara K, Horikoshi M, Kitazato H, Yamauchi T, Ito C, Noda M, Ohashi J, Froguel P, Tokunaga K, Nagai R, Kadowaki T.
    • Journal Title

      Diabetologia 48

      Pages: 1307-1314

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Expression of DGAT2 in white adipose tissue is regulated by central leptin action.2005

    • Author(s)
      Suzuki R, Tobe K, Aoyama M, Sakamoto K, Ohsugi M, Kamei N, Nemoto S, Inoue A, Ito Y, Uchida S, Hara K, Yamauchi T, Kubota N, Terauchi Y, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 280

      Pages: 3331-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Absence of an association between SNPs in the gene encoding adiponectin receptors and type 2 diabetes or insulin resistance in the Japanese population2005

    • Author(s)
      K.Hara, M.Horikoshi, H.Kitazato, T.Yamauchi, C.Ito, M.Noda, J.Ohnishi, P.Froguel, K.Tokunaga, R.Nagai, T.Kadowaki
    • Journal Title

      Diabetologia (未定)

    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeastthrough a homolog of mammalian adiponectin receptor.2005

    • Author(s)
      Narasimhan ML, Coca MA, Jin J, Yamauchi T, Ito Y, Kadowaki T, Kim KK, Pardo JM, Damsz B, Hasegawa PM, Yun DJ, Bressan RA.
    • Journal Title

      Molecular Cell 17

      Pages: 171-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.2005

    • Author(s)
      Hara K, Horikoshi M, Kitazato H, Yamauchi T, Ito C, Noda M, Ohashi J, Froguel P, Tokunaga K, Nagai R, Kadowaki T.
    • Journal Title

      Diabetologia 48

      Pages: 1307-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Expression of DGAT2 in white adipose tissue is regulated by central leptin action.2005

    • Author(s)
      Suzuki R, Tobe K, Aoyama M, Sakamoto K, Ohsugi M, Kamei N, Nemoto S, Inoue A, Ito Y, Uchida S, Hara K, Yamauchi T, Kubota N, Terauchi Y, Kadowaki T.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 3331-3337

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Adiponectin and adiponectin receptors2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr Rev 26(3):

      Pages: 439-51

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390263
  • [Journal Article] Adiponectin and adiponectin receptors2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr Rev 26

      Pages: 439-451

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209030
  • [Journal Article] Adiponectin and adiponectin receptors.2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr Rev 26(3)

      Pages: 439-451

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Adiponectin and adiponectin receptors2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr Rev 26(3)

      Pages: 439-451

    • Data Source
      KAKENHI-PROJECT-15081202
  • [Journal Article] Kruppel-like transcription factor KLF5 is a key_regulator of adipocyte differentiation.2005

    • Author(s)
      Oishi Y, Manabe I, Tobe K, Tsushima K, Shindo T, Fujiu K, MD; Nishimura, Maemura K, Yamauchi T, Kubota N, Suzuki R, Kitamura T, Akira S, Kadowaki T, Nagai R.
    • Journal Title

      Cell Metabolism 1

      Pages: 27-39

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Nuclear receptors as targets for drug development : molecular mechanisms for regulation of obesity and insulin resistance by peroxisome proliferator-activated receptor gamma, CREB-binding protein, and adiponectin.2005

    • Author(s)
      Tsuchida A, Yamauchi T, Kadowaki T.
    • Journal Title

      J. Pharmacol. Sci. 97

      Pages: 164-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Adiponectin and adiponectin receptors2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr Rev 26

      Pages: 439-451

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390263
  • [Journal Article] Angiopoietin-related growth factor antagonizes obesity and insulin resistance.2005

    • Author(s)
      Oike Y, Akao M, Yasunaga K, Yamauchi T, Morisada T, Ito Y, Urano T, Kimura Y, Kubota Y, Maekawa H, Miyamoto T, Miyata K, Matsumoto SI, Sakai J, Nakagata N, Takeya M, Koseki H, Ogawa Y, Kadowaki T, Suda T.
    • Journal Title

      Nature Medicine 11

      Pages: 400-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population2005

    • Author(s)
      Iwasaki N, Horikawa Y, Tsuchiya T, Kitamura Y, Nakamura T, Tanizawa Y, Oka Y, Hara K, Kadowaki T, Awata T, Honda M, Yamashita K, Oda N, Yu L, Yamada N, Ogata M, Kamatani N, Iwamoto Y, Del Bosque-Plata L, Hayes MG, Cox NJ, Bell GI.
    • Journal Title

      J Hum Genet Feb 5

    • NAID

      10014513339

    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Adiponectin and adiponectin receptors2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr Rev 26(3):

      Pages: 439-51

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209030
  • [Journal Article] Adiponectin and adiponectin receptors2005

    • Author(s)
      Kadowaki T, et al.
    • Journal Title

      Endocr Rev 26(3)

      Pages: 439-451

    • Data Source
      KAKENHI-PROJECT-16209030
  • [Journal Article] Insulin receptor substrate-2 plays a crucial role in p cells and the hypothalamus.2004

    • Author(s)
      Kubota N, Terauchi Y, Tobe K, Yano W, Suzuki R, Ueki K, Takamoto I, Satoh H, Maki T, Kubota T, Moroi M, Okada-Iwabu M, Ezaki O, Naigi R, Ueta Y, Kadowaki T, Noda T.
    • Journal Title

      J. Clin. Invest 114

      Pages: 917-927

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Increased serum leptin protects from adiposity despite the increased glucose upt ake in white adipose tissue in mice lacking p85alpha PI 3-kinase.2004

    • Author(s)
      Terauchi Y, Matsui J, Kamon J, Yamauchi T, Kubota N, Komeda K, Aizawa S, Akanuma Y, Tomita M, Kadowaki T
    • Journal Title

      Diabetes 53

      Pages: 2261-2270

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Dysadipocytokinemia in werner syndrome and its recovery by treatment with pioglitazone2004

    • Author(s)
      Yokote K, Hara K, Mori S, Kadowaki T, Saito Y, Goto M
    • Journal Title

      Diabetes Care 27・10

      Pages: 2562-2563

    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Insulin/Foxol pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity.2004

    • Author(s)
      Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, Kamon J, Kobayashi M, Suzuki R, Ham K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, Accili D, Tobe K, Ueki K, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 30817-30822

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] A novel IKK beta inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance.2004

    • Author(s)
      Kamon J, Yamauchi T, Muto S, Takekawa S, Ito Y, Hada Y, Ogawa W, Itai A, Kasuga M, Tobe K, Kadowaki T.
    • Journal Title

      Biochem. Biophys. Res. Commun. 323

      Pages: 242-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous PPARγ-deficient mice on a high-fat diet.2004

    • Author(s)
      Matsui J, Terauchi Y, Kubota N, Takamoto I, Eto K, Yamashita T, Komeda K, Yamauchi T, Kamon J, Kita S, Noda M, Kadowaki T.
    • Journal Title

      Diabetes 53

      Pages: 2844-2854

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1.2004

    • Author(s)
      Waki H.Yamauchi T.Kamon J.Kita S.Ito Y.Hada Y.UchidaS.Tsuchida A.Takekawa S., Kadowaki T.
    • Journal Title

      Endocrinology 146

      Pages: 790-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] SH2-containing inositol phosphatase 2 predominantly regulates akt2, and not akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes.2004

    • Author(s)
      Sasaoka T, Wada T, Fukui K, Murakami S, Ishihara H, Suzuki R, Tobe K, Kadowaki T, Kobayashi M.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 14835-14843

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Insulin/Foxol pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity.2004

    • Author(s)
      Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, Kamon J, Kobayashi M, Suzuki R, Hara K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, Accili D, Tobe K, Ueki K, Nagai R, Kadowaki T.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 30817-30822

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Protective Role of Imatinib in Atherosclerosis.2004

    • Author(s)
      Kadowaki T
    • Journal Title

      Arteriosclerosis, Thrombosis and Vascular Biology 24

      Pages: 801-803

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Both insulin signaling defects in the liver and obesity contribute to insulin resistance and cause diabetes in IRS2-/- mice.2004

    • Author(s)
      Suzuki R, Tobe K, Aoyama M, Yamauchi T, Kamon J, Kubota N, Terauchi Y, Yoshimitsu H, Matsuhisa M, Nagasaka S, Ogata H, Tokuyama K, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 25039-25049

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Role of UCP-2 up-regulation and TG accumulation in impaired glucose-stimulated insulin secretion in a β-Cell lipotoxicity model overexpressing SREBP-1c.2004

    • Author(s)
      Yamashita T, Eto K, Okazaki Y, Yamashita S, Yamauchi T, Sekine N, Nagai R, Noda M, Kadowaki T.
    • Journal Title

      Endocrinology 145

      Pages: 3566-3577

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Impairment of bone healing by insulin receptor substrate-1 deficiency.2004

    • Author(s)
      Shimoaka T, Kamekura S, Chikuda H, Hoshi K, Chung U, Akune T, Maruyama Z, Komori T, Matsumoto M, Ogawa W, Terauchi Y, Kadowaki T, Nakamura K, Kawaguchi H.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 15314-15322

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Establishment of a method of anonymization of DNA samples in genetic research.2003

    • Author(s)
      Hara K, Ohe K, Kadowaki T, Kato N, Imai Y, Tokunaga K, Nagai R, Omata M.
    • Journal Title

      J Hum Genet 48

      Pages: 327-330

    • NAID

      10011595061

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Establishment of a method of anonymization of DNA samples in genetic research.2003

    • Author(s)
      Hara K, Ohe K, Kadowaki T, Kato N, Imai Y, Tokunaga K, Nagai R, Omata M.
    • Journal Title

      J Hum Genet 48

      Pages: 327-330

    • NAID

      10011595061

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Molecular mechanism of insulin resistance and obesity.2003

    • Author(s)
      Kadowaki T
    • Journal Title

      Exp. Biol. Med. 228

      Pages: 1111-1117

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.2003

    • Author(s)
      Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Ham K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T.
    • Journal Title

      Nature 423

      Pages: 762-769

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Molecular mechanism of insulin resistance and obesity.2003

    • Author(s)
      Kadowaki T, Hara K, Yamauchi T, Terauchi Y, Tobe K, Nagai R.
    • Journal Title

      Exp. Biol. Med. 228

      Pages: 1111-1117

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin.2003

    • Author(s)
      Waki H, Yamauchi T, Kamon J, Ito Y, Uchida S, Kita S, Hara K, Hada Y, Vasseur F, Froguel P, Kimura S, Nagai R, Kadowaki T.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 40352-40363

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Molecular mechanism of insulin resistance and obesity.2003

    • Author(s)
      Kadowaki T, Hara K, Yamauchi T, Terauchi Y, Tobe K, Nagai R.
    • Journal Title

      Exp.Biol.Med. 228

      Pages: 1111-1117

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Globular adiponectin protected ob/ob mice from diabetes and apoE deficient mice from atherosclerosis.2003

    • Author(s)
      Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, Uchida S, Ito Y, Matsui J, Eto K, Komeda K, Tsunoda M, Murakami K, Ohnishi Y, Yamamura K, Ueyama Y, Froguel P, Kimura S, Nagai R, Kadowaki T.
    • Journal Title

      J. Riot Chem. 278

      Pages: 2461-2468

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Dual roles of adiponectin/Acrp30 in vivo as an anti-diabetic and anti-atherogenic adipokine.2003

    • Author(s)
      Yamauchi T, Hara K, Kubota N, Terauchi Y, Tobe K, Froguel P, Nagai R, Kadowaki T.
    • Journal Title

      Curr Drug Targets Immune Endocr Metabol Disord 3

      Pages: 243-254

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Molecular mechanism of insulin resistance and obesity.2003

    • Author(s)
      Kadowaki T et al.
    • Journal Title

      Exp. Biol. Med. 228

      Pages: 1111-1117

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15310138
  • [Journal Article] Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin.2003

    • Author(s)
      Waki H, Yamauchi T, Kamon J, Ito Y, Uchida S, Kita S, Hara K, Hada Y, Vasseur F, Froguel P, Kimura S, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 278

      Pages: 40352-40363

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Dual roles of adiponectin/Acrp30 in vivo as an anti-diabetic and anti-atherogenic adipokine.2003

    • Author(s)
      Yamauchi T, Hara K, Kubota N, Terauchi Y, Tobe K, Froguel P, Nagai R, Kadowaki T.
    • Journal Title

      Curr Drug Targets Immune Endocr Metabol Disord 3

      Pages: 243-254

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] The role of PPAR gamma in high-fat diet-induced obesity and insulin resistance.2002

    • Author(s)
      Kadowaki T
    • Journal Title

      J Diabetes Complications 16

      Pages: 41-45

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Disruption of adiponectin causes insulin resistance and neointimal formation.2002

    • Author(s)
      Kubota N, Terauchi Y, Yamauchi T, Kubota T, Moroi M, Matsui J, Eto K, Yamashita T, Kamon J, Satoh H, Yano W, Froguel P, Nagai R, Kimura S, Kadowaki T, Noda T.
    • Journal Title

      J. Biol. Chem 277

      Pages: 25863-25866

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.2002

    • Author(s)
      Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, Yamashita S, Noda M, Kita S, Ueki K, Eto K, Akanuma Y, Froguel P, Foufelle F, Ferre P, Carling D, Kimura S, Nagai R, Kahn BB, Kadowaki T.
    • Journal Title

      Nature Medicine 8

      Pages: 1288-1295

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Maturity-onset diabetes of the young resulting from a novel mutation in the HNF-4alpha gene.2002

    • Author(s)
      Hara K, Noda M, Waki H, Tobe K, Yamauchi T, Kadowaki H, Satou H, Tsukamoto K, Nagamatsu S, Yamagata K, Matsuzawa Y, Akanuma Y, Kimura S, Kadowaki T.
    • Journal Title

      Intern Med 41

      Pages: 848-852

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] The role of PPAR gamma in high-fat diet-induced obesity and insulin resistance.2002

    • Author(s)
      Kadowaki T, Hara K, Kubota N, Tobe K, Terauchi Y, Yamauchi T, Eto K, Kadowaki H, Noda M, Hagura R, Akanuma Y.
    • Journal Title

      J Diabetes Complications 16

      Pages: 41-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.2002

    • Author(s)
      Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, Yamauchi T, Otabe S, Okada T, Eto K, Kadowaki H, Hagura R, Akanuma Y, Yazaki Y, Nagai R, Taniyama M, Matsubara K, Yoda M, Nakano Y, Tomita M, Kimura S, Ito C, Froguel P, Kadowaki T.
    • Journal Title

      Diabetes 51

      Pages: 536-540

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians.2002

    • Author(s)
      Vasseur F, Helbecque N, Dina C, Lobbens S, Delannoy V, Gaget S, Boutin P, Vaxillaire M, Lepretre F, Dupont S, Hara K, Clement K, Bihain B, Kadowaki T, Froguel P.
    • Journal Title

      Hum Mol Genet 11

      Pages: 2607-2614

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Froguel P. Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p.2002

    • Author(s)
      Mori Y, Otabe S, Dina C, Yasuda K, Populaire C, Lecoeur C, Vatin V, Durand E, Ham K, Okada T, Tobe K, Boutin P, Kadowaki T
    • Journal Title

      Diabetes 51

      Pages: 1247-1255

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes.2002

    • Author(s)
      Hara K, Tobe K, Okada T, Kadowaki H, Akanuma Y, Ito C, Kimura S, Kadowaki T.
    • Journal Title

      Diabetologia 45

      Pages: 740-743

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.2002

    • Author(s)
      Yamauchi T, Oike Y, Kamon J, Waki H, Komeda K, Tsuchida A, Date Y, Li MX, Miki H, Akanuma Y, Nagai R, Kimura S, Saheki T, Nakazato M, Naitoh T, Yamamura K, Kadowaki T.
    • Journal Title

      Nature Genetics 30

      Pages: 221-226

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] The Pro12→Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population : possible involvement in impairment of insulin secretion in individuals with type 2 diabetes.2002

    • Author(s)
      Mori H, Ikegami H, Kawaguchi Y, Seino S, Yokoi N, Takeda J, Inoue I, Seino Y, Yasuda K, Hanafusa T, Yamagata K, Awata T, Kadowaki T, Hara K, Yamada N, Gotoda T, Iwasaki N, Iwamoto Y, Sanke T, Nanjo K, Oka Y, Matsutani A, Maeda E, Kasuga M.
    • Journal Title

      Diabetes 50

      Pages: 891-894

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Variants of neurogenin 3 gene are not associated with Type II diabetes in Japanese subjects.2001

    • Author(s)
      Okada T, Tobe K, Hara K, Yasuda K, Kawaguchi Y, Ikegami H, Ito C, Kadowaki T.
    • Journal Title

      Diabetologia 44

      Pages: 241-244

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.2001

    • Author(s)
      Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, AkanumaY, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T.
    • Journal Title

      Nature Medicine 7

      Pages: 941-946

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.

    • Author(s)
      Kadowaki T, et al.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Association of adenovirus 36 infection with obesity and metabolic markers in humans: a meta-analysis of observational studies

    • Author(s)
      Yamada T, Hara K, Kadowaki T
    • Journal Title

      PLoS One

      Volume: 7

    • Data Source
      KAKENHI-PROJECT-20229008
  • [Patent] Activator of adiponectin receptor2020

    • Inventor(s)
      門脇 孝、山内 敏正、岩部 美紀、岩部 真人、横山 茂之, 他
    • Industrial Property Rights Holder
      国立大学法人東京大学/理化学研究所
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2020
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Patent] アディポネクチン受容体活性化化合物2020

    • Inventor(s)
      門脇 孝、山内 敏正、岩部 美紀、岩部 真人、横山 茂之, 他
    • Industrial Property Rights Holder
      国立大学法人東京大学/理化学研究所
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2020
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Patent] Activator of adiponectin receptor2017

    • Inventor(s)
      門脇孝、山内敏正、岩部美紀、岩部真人、横山茂之、本間光貴
    • Industrial Property Rights Holder
      国立大学法人東京大学/理化学研究所
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Patent] アディポネクチン受容体活性化化合物2014

    • Inventor(s)
      門脇孝, 山内敏正, 岩部真人, 岩部美紀, 横山茂之
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-09-30
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Patent] 擬似運動療法のための医薬2011

    • Inventor(s)
      門脇孝、山内敏正、他2名
    • Industrial Property Rights Holder
      (株)東京大学TLO
    • Filing Date
      2011-03-15
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Patent] アディポネクチン受容体及びそれをコードする遺伝子2010

    • Inventor(s)
      門脇孝、山内敏正、他2名
    • Industrial Property Rights Holder
      東京大学TLO、日産化学工業(株)
    • Acquisition Date
      2010-01-22
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Patent] 遺伝子多型を用いた2型糖尿病の検査方法2007

    • Inventor(s)
      安田和基、春日雅人、門脇孝、古田浩人、牧野英一、岩崎直子、堀川幸男、山縣和也、岡芳知
    • Industrial Property Rights Holder
      国立国際医療センター, 他
    • Industrial Property Number
      2007-325366
    • Filing Date
      2007-12-18
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Patent] 遺伝子多型をもちいた二型糖尿病の検査方法2007

    • Inventor(s)
      安田 和基, 春日 雅人, 門脇 孝, 古田 浩人, 牧野 英一, 岩崎 直子, 堀川 幸男, 山縣 和也, 岡 芳知
    • Industrial Property Rights Holder
      国立国際医療センター, 神戸大学, 東京大学, 愛媛大学, 岐阜大学
    • Industrial Property Number
      2007-325366
    • Filing Date
      2007-12-18
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Patent] A Homolog of Adiponectin Receptor controls Osmotin-Induced Apoptosis in Yeast2004

    • Inventor(s)
      門脇 孝ら
    • Industrial Property Rights Holder
      門脇 孝ら
    • Filing Date
      2004-09-28
    • Data Source
      KAKENHI-PROJECT-16209030
  • [Patent] Adiponectin Negatively Regulates Leptin Sensitivity2004

    • Inventor(s)
      門脇 孝ら
    • Industrial Property Rights Holder
      門脇 孝ら
    • Filing Date
      2004-08-20
    • Data Source
      KAKENHI-PROJECT-15659216
  • [Patent] A Homolog of Adiponectin Receptor controls Osmotin-Induced Apoptosis in Yeast2004

    • Inventor(s)
      門脇 孝ら
    • Industrial Property Rights Holder
      門脇 孝ら
    • Filing Date
      2004-09-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209030
  • [Patent] A homolog of human adiponectin receptor controls osmotin-induced apoptosis in yeast2004

    • Inventor(s)
      Narasimhan ML, Yun DJ, Bressan RA, 山内敏正, 門脇孝
    • Industrial Property Rights Holder
      Narasimhan ML, Yun DJ, Bressan RA, 山内敏正, 門脇孝
    • Filing Date
      2004-09-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Patent] アディポネクチンの新規用途2003

    • Inventor(s)
      門脇孝, 山内敏正, 高田誠, 他1名
    • Industrial Property Rights Holder
      門脇孝, 住友製薬(株)
    • Filing Date
      2003-05-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Patent] 2型糖尿病の診断又は検査方法2002

    • Inventor(s)
      原一雄, 門脇孝 他3名
    • Industrial Property Rights Holder
      科学技術振興事業団
    • Patent Publication Number
      2004-049033
    • Filing Date
      2002-07-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Presentation] Molecular mechanism of insulin resistance and comorbidities linked to obesity2021

    • Author(s)
      Kadowaki T
    • Organizer
      Asia-Oceania Conference on Obesity and Malaysian Association for Study of Obesity Scientific Conference (AOCO-MASO2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] 2型糖尿病 ―成因と治療の最新知見2021

    • Author(s)
      門脇 孝
    • Organizer
      第22回日本内分泌学会中国支部学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] 理事長提言2021

    • Author(s)
      門脇 孝
    • Organizer
      第41回 日本肥満学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] Molecular mechanism of obesity-linked insulin resistance and type 2 diabetes2021

    • Author(s)
      Kadowaki T
    • Organizer
      Sabri Ulker Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] Molecular mechanism of Thyoe 2 Diabetes and Insulin Resistance2021

    • Author(s)
      Takashi Kadowaki
    • Organizer
      TORONTO VIRTUAL PRESENTATION AT CITY-WIDE ENDOCRINE ROUNDS
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] 糖尿病・代謝学の展望2020

    • Author(s)
      門脇 孝
    • Organizer
      第30回 臨床内分泌代謝Update
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] Molecular mechanism of obesity-linked comorbidities2020

    • Author(s)
      Takashi Kadowaki
    • Organizer
      International Congress on Obesity and Metabolic Syndrome
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] 糖尿病学会への提言2020

    • Author(s)
      門脇 孝
    • Organizer
      第63回 日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] What is type 2 diabetes? A long journey to seek the truth2020

    • Author(s)
      Takashi Kadowaki
    • Organizer
      56th EASD Annual Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] Elucidation of roles of insulin resistance and decreased adiponectin action in type 2 diabetes and diabetes complications and development of their therapeutic strategy2019

    • Author(s)
      Takashi Kadowaki
    • Organizer
      International Diabetes Federation 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Adiponectin receptor (AdipoR) and skeletal muscle Akt.2019

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Regulators of anti-aging : Cold Spring Harbor Laboratory Meeting Mechanisms of Metabolic Signaling
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] 2型糖尿病研究の戦略と将来展望2019

    • Author(s)
      門脇 孝
    • Organizer
      第33回日本糖尿病・肥満動物学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Adiponectin receptor (AdipoR) and skeletal muscle Akt.2019

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Regulators of anti-aging : Cold Spring Harbor Laboratory Meeting Mechanisms of Metabolic Signaling
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Medical Research by Physician Scientist2019

    • Author(s)
      門脇 孝
    • Organizer
      第83回日本循環器学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病治療の現状と将来展望2019

    • Author(s)
      門脇 孝
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病治療の現状と将来展望2019

    • Author(s)
      門脇 孝
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] 2型糖尿病治療の最新情報2019

    • Author(s)
      門脇 孝
    • Organizer
      第22回日本病態栄養学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Elucidation of roles of insulin resistance and decreased adiponectin action in type 2 diabetes and diabetes complications and development of their therapeutic strategy2019

    • Author(s)
      Takashi Kadowaki
    • Organizer
      International Diabetes Federation 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01052
  • [Presentation] 『健康な食事・食環境』推進の科学的根拠 -肥満および糖尿病予防の観点から-2018

    • Author(s)
      門脇 孝
    • Organizer
      第65回日本栄養改善学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 健康長寿を目指す糖尿病治療戦略2018

    • Author(s)
      門脇 孝
    • Organizer
      第68回日本体質学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Insulin signalling in obesity and type 2 diabetes2018

    • Author(s)
      Takashi Kadowaki
    • Organizer
      18th International Congress of Endocrinology and 53rd SEMDSA Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] アディポネクチン受容体の構造と機能2018

    • Author(s)
      岩部(岡田)美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第12回 炎症・脂質代謝・メタボリサーチフォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] 管理が困難な糖尿病とその対策2018

    • Author(s)
      門脇 孝
    • Organizer
      第115回 日本内科学会総会・講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Newstrategies for the prevention of cardiovascular and renal diseases in type 2 diabetes2018

    • Author(s)
      Takashi Kadowaki
    • Organizer
      2018 ISN Frontiers Meeting “Kidney Disease & Cardiovascular Disease” in Tokyo
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病の病態と治療戦略2018

    • Author(s)
      門脇 孝
    • Organizer
      日本糖尿病学会 中国四国地方会 第56回総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 日本肥満学会の更なる発展のために2018

    • Author(s)
      門脇 孝
    • Organizer
      第39回日本肥満学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Molecular Mechanism of Type 2 Diabetes : Perspectives from Insulin Receptor and Adiponectin Receptor Actions2018

    • Author(s)
      Takashi Kadowaki
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病の治療戦略-J-DOIT3から学ぶもの2018

    • Author(s)
      門脇 孝
    • Organizer
      第52回糖尿病学の進歩
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 大学発の新規生活習慣病治療薬開発におけるトランスレーショナルリサーチの実現に向けて2018

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      東大病院先端医療シーズ開発フォーラム2018
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] 糖尿病と肝臓病 -肝臓学会と糖尿病学会の一層の連携に向けて2018

    • Author(s)
      門脇 孝
    • Organizer
      第54回日本肝臓学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] DREAMS実現 -新たなステージへ- ~還暦を迎えた学会の使命~2018

    • Author(s)
      門脇 孝
    • Organizer
      第61回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 高齢者糖尿病の病態と治療2018

    • Author(s)
      門脇 孝
    • Organizer
      第67回日本老年医学会関東甲信越地方会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Novel structures and functions of adiponectin receptors2017

    • Author(s)
      岩部(岡田)美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      DISIRE Conference 2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] アディポネクチン受容体の立体構造情報を利用したアゴニストの最適化に向けた検討2017

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第60回 日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] Adiponectin as an Anti-Aging Regulation2017

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Keystone Symposia, Aging and Mechanisms of Aging-Related Disease Signal Transduction II-Mitochondria
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「アディポネクチン受容体の抗体創薬に向けた検討と解析」2017

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第10回 システム疾患生命科学による先端医療技術開発シンポジウム
    • Place of Presentation
      東京大学武田先端知ビル(東京都文京区)
    • Year and Date
      2017-03-11
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] 2型糖尿病の成因と治療-真理の追究2017

    • Author(s)
      門脇 孝
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Role of insulin receptor substrates in liver and macrophage in obesity-linked insulin resistance2017

    • Author(s)
      Takashi Kadowaki
    • Organizer
      R2017 13th International Symposium on the Insulin Receptor and Insulin Action
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Adiponectin Receptor : Structure, Function and Role in Obesity and Diabetes2017

    • Author(s)
      Takashi Kadowaki
    • Organizer
      UTokyo-NTU Joint Meeting 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Mechanism of insulin resistance in type 2 diabetes - a new concept2017

    • Author(s)
      Takashi Kadowaki
    • Organizer
      3rd Korea-Japan Diabetes Forum in conjunction with 30th Spring Congress of Korean Diabetes Association
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「アディポネクチン受容体の抗体創薬に向けた検討と解析」2017

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第10回 システム疾患生命科学による先端医療技術開発シンポジウム
    • Place of Presentation
      東京大学武田先端知ビル(東京都文京区)
    • Year and Date
      2017-03-11
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] Adiponectin Receptor : A Major Treatment Target in Type 2 Diabetes and Obesity-Linked Diseases2017

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Keystone Symposia Diabetes /Obesity and Adipose Tissue Biology
    • Place of Presentation
      Colorado (USA)
    • Year and Date
      2017-01-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「大学発の新規糖尿病治療薬開発におけるトランスレーショナルリサーチの実現を目指して」2017

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      東大病院先端医療シーズ開発フォーラム2017
    • Place of Presentation
      東京大学伊藤国際学術研究センター (東京都文京区)
    • Year and Date
      2017-02-02
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] 肝臓のエネルギー代謝:センシングと病態(シンポジウム)「インスリン抵抗性の新視点―肝臓のmetabolic zonation―」2017

    • Author(s)
      窪田直人,窪田哲也,門脇孝
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Presentation] 2型糖尿病の成因と治療戦略2017

    • Author(s)
      門脇 孝
    • Organizer
      第54回日本糖尿病学会近畿地方会・第53回日本糖尿病協会近畿地方会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] アディポネクチン・アディポネクチン受容体研究の最前線2017

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第38回 日本肥満学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] 腎症重症化予防に向けた日本糖尿病学会の活動2017

    • Author(s)
      門脇 孝
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病の成因と治療戦略2017

    • Author(s)
      門脇 孝
    • Organizer
      第55回日本糖尿病学会九州地方会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「大学発の新規糖尿病治療薬開発におけるトランスレーショナルリサーチの実現を目指して」2017

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      東大病院先端医療シーズ開発フォーラム2017
    • Place of Presentation
      東京大学伊藤国際学術研究センター (東京都文京区)
    • Year and Date
      2017-02-02
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] 糖尿病に対する現在の内科治療の現状外科的治療に対するコメント2017

    • Author(s)
      門脇 孝
    • Organizer
      第117回日本外科学会定例学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] アディポネクチン受容体アゴニストの糖尿病治療への応用に向けた検討と解析2017

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第90回 日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] DREAMS実現への架け橋~超高齢社会の中で還暦を迎える学会の使命~2017

    • Author(s)
      門脇 孝
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「アディポネクチン受容体の立体構造とアゴニストの最適化に向けた検討と解析」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第89回 日本内分泌学会学術総会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] Adiponectin and its Receptors : implications for Health and Disease2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      The Asian Pacific Congress of Nephrology 2016
    • Place of Presentation
      Perth (Australia)
    • Year and Date
      2016-09-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 【特別企画2 : 糖尿病領域における臨床研究の課題】 : 「研究活動に係る倫理行動規範」2016

    • Author(s)
      門脇 孝
    • Organizer
      第50回糖尿病学の進歩
    • Place of Presentation
      東京国際フォーラム(東京都・千代田区)
    • Year and Date
      2016-02-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「アディポネクチン受容体アゴニストの肥満症治療への応用に向けた挑戦」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第37回 日本肥満学会
    • Place of Presentation
      東京ファッションタウンビル(東京都江東区)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] 「アディポネクチン受容体の構造と機能解明」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第21回 アディポサイエンスシンポジウム
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2016-08-20
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] Elucidation of the molecular mechanism of “selective insulin resistance” in the liver2016

    • Author(s)
      窪田直人、窪田哲也、門脇孝
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Presentation] アディポネクチン・AdipoRの 肥満症における病態生理的意義2016

    • Author(s)
      山内敏正、岩部美紀 岩部真人 門脇 孝
    • Organizer
      第89回日本内分泌学会学術総会
    • Place of Presentation
      京都国際会館(京都市)
    • Year and Date
      2016-04-20
    • Data Source
      KAKENHI-PROJECT-26253058
  • [Presentation] 「アディポネクチン受容体の立体構造とアゴニストの最適化に向けた検討と解析」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第59回 日本糖尿病学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] Adiponectin and its receptor : A major role in type 2 diabetes and obesity-linked disease2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      The 11th IDF-WPR congress & 8th AASD Scientific Meeting 2016
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2016-10-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] アディポネクチン受容体の抗体創薬に向けた検討と解析2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第9回システム疾患生命科学による先端医療技術開発シンポジウム
    • Place of Presentation
      東京大学山上会館(東京都文京区)
    • Year and Date
      2016-02-12
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] 肝臓の「選択的インスリン抵抗性」には正常なIRS-1の発現とIRS-2の発現低下が重要である2016

    • Author(s)
      窪田直人、窪田哲也、井上真理子、高本偉碩、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第37回日本肥満学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Presentation] 「アディポネクチン受容体の立体構造とアゴニストの最適化に向けた検討と解析」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第89回 日本内分泌学会学術総会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] Brown and White adipose tissues in obesity and type2 diabetes2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      KVA-JSPS Seminar Series “Molecular mechanism of insulin resistance and type 2 diabetes”
    • Place of Presentation
      Stockholm (Sweden)
    • Year and Date
      2016-02-03
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] エネルギー代謝と心血管病 糖尿病と心血管病 糖尿病治療が血管合併症を抑制する分子機構の検討2016

    • Author(s)
      窪田直人、窪田哲也、門脇孝
    • Organizer
      第89回日本内分泌学会学術総会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Presentation] Adiponectin and adiponectin receptors : Roles in obesity-linked diseases and novel therapeutic strategy2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      AMPK 2016 : NEW MECHANISMS and PHYSIOLOGY
    • Place of Presentation
      Xiamen (China)
    • Year and Date
      2016-11-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Molecular Mechanism of insulin resistance and type2 diabetes2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      KVA-JSPS Seminar Series “Molecular mechanism of insulin resistance and type 2 diabetes”
    • Place of Presentation
      Stockholm (Sweden)
    • Year and Date
      2016-02-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Molecular Mechanism of Obesity-Linked Insulin Resistance and Comorbidities2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      American Society of Nephrology
    • Place of Presentation
      Chicago (USA)
    • Year and Date
      2016-11-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病治療における患者中心医療2016

    • Author(s)
      門脇 孝
    • Organizer
      第30回日本臨床内科学会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2016-10-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 私と糖尿病2016

    • Author(s)
      門脇 孝
    • Organizer
      第3回日本糖尿病医療学学会
    • Place of Presentation
      京都大学百周年 時計台記念館(京都府・京都市)
    • Year and Date
      2016-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Adiponectin receptor in obesity-associated disease : Pathophysiology and therapeutic Strategy2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      International Symposium of the Center for Animal Disease Models 2016 -Metabolic disease and Aging-
    • Place of Presentation
      Tokyo (Japan)
    • Year and Date
      2016-07-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Plenary Lecture : Implications for obesity associated diseases2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Long Beach, California 2016 Rachmiel Levine-Arthur Riggs Symposium
    • Place of Presentation
      Long Beach (U.S.A.)
    • Year and Date
      2016-03-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「アディポネクチン受容体アゴニストの肥満症治療への応用に向けた挑戦」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第37回 日本肥満学会
    • Place of Presentation
      東京ファッションタウンビル(東京都江東区)
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-16K15487
  • [Presentation] 「アディポネクチン受容体の構造と機能解明」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第21回 アディポサイエンスシンポジウム
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2016-08-20
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] DREAMSの成果と更なる実現2016

    • Author(s)
      門脇 孝
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「アディポネクチン受容体の立体構造とアゴニストの最適化に向けた検討と解析」2016

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第59回 日本糖尿病学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] Genetic and environmental factors in the pathogenesis of type 2 diabetes2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      KVA-JSPS Seminar Series “Molecular mechanism of insulin resistance and type 2 diabetes”
    • Place of Presentation
      Stockholm (Sweden)
    • Year and Date
      2016-02-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Meta analysis and critical review on efficacy of TZDs in Asian population2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      The 11th IDF-WPR congress & 8th AASD Scientific Meeting 2016
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2016-10-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 【特別企画3 : 私の人生を変えたこの論文-若手医師・研究者へのメッセージ】 : 「私の研究者としての人生を変えた論文ー発生工学技術の発見」2016

    • Author(s)
      門脇 孝
    • Organizer
      第50回糖尿病学の進歩
    • Place of Presentation
      東京国際フォーラム(東京都・千代田区)
    • Year and Date
      2016-02-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「専門医単位更新のための指定講演」 : 「2型糖尿病成因Update」2016

    • Author(s)
      門脇 孝
    • Organizer
      第50回糖尿病学の進歩
    • Place of Presentation
      東京国際フォーラム(東京都・千代田区)
    • Year and Date
      2016-02-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病の成因解明と治療戦略-30年の歩み2016

    • Author(s)
      門脇 孝
    • Organizer
      第113回日本内科学会総会・講演会
    • Place of Presentation
      東京国際フォーラム(東京都・千代田区)
    • Year and Date
      2016-04-16
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Type 2 diabetes : From genes to therapies2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      The 13th International Congress of Human Genetics
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2016-04-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Adiponectin Receptors : Functional Mechanisms and Therapeutic Implications2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Frontier in Immunometabolism
    • Place of Presentation
      Hong Kong (China)
    • Year and Date
      2016-04-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 30周年記念講演 : 「日本糖尿病・肥満動物学会の発展の歴史と今後の期待」2016

    • Author(s)
      門脇 孝
    • Organizer
      第30回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      大宮ソニックシティ(埼玉県・さいたま市)
    • Year and Date
      2016-03-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Adiponectin Receptor In Metabolic Disease And Cancer : Pathophysiology And Therapeutic Strategy2016

    • Author(s)
      Takashi Kadowaki
    • Organizer
      The XIII International Congress on Obesity
    • Place of Presentation
      Vancouver (Canada)
    • Year and Date
      2016-05-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] アディポネクチン受容体の立体構造の解明2016

    • Author(s)
      門脇 孝
    • Organizer
      CBI学会2016年大会
    • Place of Presentation
      タワーホール船堀(東京都・江戸川区)
    • Year and Date
      2016-10-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] アディボネクチンと抗加齢医学2016

    • Author(s)
      門脇 孝
    • Organizer
      第16回日本抗加齢医学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-06-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Crystal structures of the human adiponectin receptors2015

    • Author(s)
      MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
    • Organizer
      2016 Keystone Symposia Conference T2: Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies
    • Place of Presentation
      Westin Miyako Kyoto(京都府京都市)
    • Year and Date
      2015-10-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] アディポネクチンを標的とした糖尿病・糖尿病合併症の治療2015

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第88回 日本内分泌学会学術総会
    • Place of Presentation
      ホテルニューオータニ(東京都千代田区)
    • Year and Date
      2015-04-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] Diabetes and Healthy Lifespan : Adiponectin Receptor and Metabolic Syndrome : Pathophysiology and Therapeutic Strategy2015

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Keystone Symposia Conference-Diabetes : New Insights into Molecular Mechanisms and Therapeutic Strategies
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2015-10-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Solving the type2 diabetes dilemma : where to we focus? : Improving insulin sensitivity2015

    • Author(s)
      Takashi Kadowaki
    • Organizer
      IDF World Diabetes Congress 2015
    • Place of Presentation
      Vancouver (Canada)
    • Year and Date
      2015-12-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 健康長寿を目指した糖尿病治療薬開発に向けたアディポネクチン受容体アゴニストの創製2015

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第58回 日本糖尿病学会年次学術集会
    • Place of Presentation
      グランプラス セント・バレンタイン(山口県下関市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] 糖尿病の病態に応じた治療薬の選択は如何にあるべきか「2型糖尿病の病態に応じた治療薬の選択と併用療法のすすめ方」2015

    • Author(s)
      門脇 孝
    • Organizer
      第32回糖尿病UpーDate ナゴヤ・キャッスル(賢島)セミナー
    • Place of Presentation
      ウェスティンナゴヤキャッスル(愛知県・名古屋市)
    • Year and Date
      2015-08-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Mutational Analyses Based on Crystal Structures of AdipoRs Facilitate understanding of NobelStructure-Function Relationships Including Adiponectin Binding and intrasellular Signal Transduction.2015

    • Author(s)
      Toshimasa Yamauchi, Miki Okada-Iwabu, Masato Iwabu, Takashi Kadowaki
    • Organizer
      American Diabetes Association 75th Scientific Sessions
    • Place of Presentation
      ボストン(アメリカ)
    • Year and Date
      2015-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26253058
  • [Presentation] 私の留学体験記-糖尿病研究留学へのいざない-「留学の勧め-私の体験から(Aninvitation to study abroad : My experience)」2015

    • Author(s)
      門脇 孝
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      ぱしふぃっくびいなす(山口県・下関市)
    • Year and Date
      2015-05-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病における肝臓の糖・脂質代謝調節破綻の分子機構」2015

    • Author(s)
      窪田直人、窪田哲也、井上真理子、高本偉碩、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第112回日本内科学会総会
    • Place of Presentation
      京都
    • Year and Date
      2015-04-10
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Presentation] NCDsサミット『日本におけるNCDsの現状とその制圧に向けての提言』 : 日本における糖尿病の現状とその制圧に向けての提言2015

    • Author(s)
      門脇 孝
    • Organizer
      第88回日本内分泌学会学術総会
    • Place of Presentation
      ホテルニューオータニ(東京都千代田区)
    • Year and Date
      2015-04-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 肝臓における「選択的インスリン抵抗性」の分子機構の解明」2015

    • Author(s)
      窪田直人、窪田哲也、井上真理子、高本偉碩、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第36回日本肥満学会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Presentation] 2型糖尿病の分子機構と治療戦略2015

    • Author(s)
      門脇 孝
    • Organizer
      第29回日本医学会総会 2015関西
    • Place of Presentation
      グランドプリンスホテル京都(京都府・京都市)
    • Year and Date
      2015-04-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「医学生・研修医の日本内科学会ことはじめ 2015京都」内科学の勧め-臨床と研究2015

    • Author(s)
      門脇 孝
    • Organizer
      第112回 日本内科学会総会・講演会
    • Place of Presentation
      みやこめっせ(京都府・京都市)
    • Year and Date
      2015-04-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] DREAMSの成果と更なる実現2015

    • Author(s)
      門脇 孝
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      海峡メッセ下関(山口県・下関市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Adiponectin receptor and metabolic syndrome : Pathophysiology and therapeutic strategy2015

    • Author(s)
      Takashi Kadowaki
    • Organizer
      the joint 2015 Keystone Symposia on Obesity and the Metabolic Syndrome
    • Place of Presentation
      British Columbia (Canada)
    • Year and Date
      2015-03-26
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Crystal structure of the human adiponectin receptors2015

    • Author(s)
      MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
    • Organizer
      第20回 アディポサイエンスシンポジウム
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2015-08-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] 新しい糖尿病治療ガイドと新しい糖尿病治療薬への留意点2015

    • Author(s)
      門脇 孝
    • Organizer
      第32回糖尿病UpーDate ナゴヤ・キャッスル(賢島)セミナー
    • Place of Presentation
      ウェスティンナゴヤキャッスル(愛知県・名古屋市)
    • Year and Date
      2015-08-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] ゲノム医療の実装にむけて「糖尿病の個別化予防・個別化医療実現への現状と展望~多因子遺伝疾患のゲノム医療」2015

    • Author(s)
      門脇 孝
    • Organizer
      東京大学ゲノム医科学研究機構キックオフシンポジウム
    • Place of Presentation
      東京大学伊藤国際学術研究センター 伊藤謝恩ホール(東京都・文京区)
    • Year and Date
      2015-08-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] アディポネクチン受容体の抗体創薬に向けた検討と解析2015

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第8回システム疾患生命科学による先端医療技術開発シンポジウム
    • Place of Presentation
      東京大学医学部附属病院(東京都・文京区)
    • Year and Date
      2015-02-27
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] 「糖尿病合併症の成因Up to Date その発症機序の解明に迫る 血管内皮細胞をターゲットとした糖尿病合併症へのアプローチ」2015

    • Author(s)
      窪田直人、窪田哲也、門脇 孝
    • Organizer
      第30回日本糖尿病合併症学会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-11-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04847
  • [Presentation] 各学会による日本栄養療法協議会~栄養療法の標準化を目指して~2015

    • Author(s)
      門脇孝
    • Organizer
      第18回日本病態栄養学会年次学術集会
    • Place of Presentation
      国立京都国際会館 (京都府・京都市)
    • Year and Date
      2015-01-11
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] Adiponectin receptor and metabolic disease: Pathophysiology and therapeutic strategy2015

    • Author(s)
      Takashi Kadowaki
    • Organizer
      CSHL (Cold Spring Harbor Laboratory) Meeting
    • Place of Presentation
      New York (U.S.A.)
    • Year and Date
      2015-08-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 「医学生・研修医の内科学サミット」医学研究・臨床とエビデンス2014

    • Author(s)
      門脇孝
    • Organizer
      第III回日本内科学会総会
    • Place of Presentation
      東京国際フォーラム(東京都・千代田区)
    • Year and Date
      2014-04-12
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity2014

    • Author(s)
      Takashi Kadowaki
    • Organizer
      FASEB Science Research Conference (AMPK : Biological Action and Therapeutic Perspectives)
    • Place of Presentation
      Lucca (Italy)
    • Year and Date
      2014-09-29
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] The epigenome and its role in diabetes2014

    • Author(s)
      Takashi Kadowaki
    • Organizer
      10th IDF-WPR Congress
    • Place of Presentation
      Singapore(Singapore)
    • Year and Date
      2014-11-24
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] アディポネクチン受容体アゴニストの抗糖尿病作用と寿命延長効果2014

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第29回日本糖尿病合併症学会
    • Place of Presentation
      都市センターホテル(東京都・千代田区)
    • Year and Date
      2014-10-03
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] アディポネクチン受容体アゴニストの抗糖尿病作用と寿命延長効果2014

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第35回日本肥満学会
    • Place of Presentation
      ェニックスシーガイアリゾート コンベンションセンター(宮崎県・宮崎市)
    • Year and Date
      2014-10-25
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] 医学研究・臨床とエビデンス2014

    • Author(s)
      門脇 孝
    • Organizer
      第111回日本内科学会総会・講演会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] 大学の研究から大学発の創薬への挑戦ー若手の皆さんのこれからの楽しい研究生活に向けてー2014

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      2014年度臨床者育成プログラムMetabolism Research Course
    • Place of Presentation
      東京大学医学部附属病院(東京都・文京区)
    • Year and Date
      2014-06-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] 内蔵脂肪減少に着目した健康長寿への挑戦2014

    • Author(s)
      門脇孝
    • Organizer
      第35回日本肥満学会
    • Place of Presentation
      フェニックスシーガイアリゾート コンベンションセンター (宮崎県・宮崎市)
    • Year and Date
      2014-10-03
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] A small-molecule AdipoR agonist ameliorates type 2 diabetes and prolongs the shortened lifespan2014

    • Author(s)
      MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
    • Organizer
      第19回アディポサイエンスシンポジウム
    • Place of Presentation
      里ライフサイエンスセンター(大阪府・豊中市)
    • Year and Date
      2014-08-23
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] A small-molecule AdipoR agonist ameliorates type 2 diabetes and prolongs the shortened lifespan2014

    • Author(s)
      MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
    • Organizer
      American Diabetes Association, 74th Scientific Sessions
    • Place of Presentation
      SanFrancisco (USA)
    • Year and Date
      2014-06-15
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] A small-molecule AdipoR agonist ameliorates type 2 diabetes and prolongs the shortened lifespan2014

    • Author(s)
      MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
    • Organizer
      9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-09-23
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] アディポネクチン受容体アゴニストの抗糖尿病作用と寿命延長効果2014

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      ホテルNCB(大阪府・大阪市)
    • Year and Date
      2014-05-24
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] メタボリックシンドロームとは?2014

    • Author(s)
      門脇 孝
    • Organizer
      日本医学会総会2015関西特別企画
    • Place of Presentation
      東京
    • Year and Date
      2014-04-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] 2型糖尿病の「体質」の理解と先制医療の開発に向けて2014

    • Author(s)
      門脇孝
    • Organizer
      第64回日本体質医学会総会
    • Place of Presentation
      中央電気倶楽部 (大阪府・大阪市)
    • Year and Date
      2014-09-07
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病およびIGTへの対応2014

    • Author(s)
      門脇孝
    • Organizer
      第31回糖尿病Up・Date賢島セミナー
    • Place of Presentation
      志摩観光ホテル (三重県・志摩市)
    • Year and Date
      2014-08-23
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 理事長声明2014

    • Author(s)
      門脇 孝
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] Adipose tissue inflammation and B regulatory cell dysfunction2014

    • Author(s)
      Takashi Kadowaki
    • Organizer
      10th IDF-WPR Congress
    • Place of Presentation
      Singapore (Singapore)
    • Year and Date
      2014-11-24
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] 2型糖尿病とその合併症の分子基盤に関する研究2014

    • Author(s)
      門脇孝
    • Organizer
      第29回日本糖尿病合併症学会
    • Place of Presentation
      都市センターホテル (東京都・千代田区)
    • Year and Date
      2014-10-03
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity2014

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Homeodynamics in Clocks, Sleep and Metabolism-Tokyo Translational Therapeutics Meeting
    • Place of Presentation
      Tokyo (Japan)
    • Year and Date
      2014-09-24
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-26000012
  • [Presentation] アディポネクチン受容体をターゲットにした糖尿病治療薬開発の試み2014

    • Author(s)
      岩部 美紀、山内 敏正、岩部 真人、門脇 孝
    • Organizer
      第87回日本内分泌学会学術集会
    • Place of Presentation
      福岡国際会議場(福岡県・福岡市)
    • Year and Date
      2014-04-24
    • Data Source
      KAKENHI-PROJECT-26293216
  • [Presentation] チアゾリジン誘導体はアディポネクチン依存性・非依存性に動脈硬化を抑制する2012

    • Author(s)
      窪田哲也、窪田直人、佐藤寛之、岩村智勝、井上真理子、林高則、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第26回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-02-18
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2は肝臓のインスリン感受性を調節する2012

    • Author(s)
      井上真理子、窪田直人、窪田哲也、熊谷洋紀、河合智子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第26回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-02-17
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS1、IRS2の役割2012

    • Author(s)
      岩村智勝,窪田直人,窪田哲也,井上真理子,佐藤寛之,林高則,高本偉碩,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第15回日本病態栄養学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2012-01-14
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] AdipoRs activation increases Ca2+ and AMPK/SIRT/PGC-1, thereby regulating metabolic stress and mitochondria, leading to anti-aging and amelioration of diseases of aging2012

    • Author(s)
      Takashi Kadowaki
    • Organizer
      KEYSTONE SYMPOSIA: Aging and Diseases of Aging
    • Place of Presentation
      TOKYO
    • Year and Date
      2012-10-26
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Adiponectin and adiponectin receptors in insulin resistance and type 2 diabetes2011

    • Author(s)
      門脇孝
    • Organizer
      The World Diabetes Congress
    • Place of Presentation
      Dubai, UAE(招待講演)
    • Year and Date
      2011-12-04
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 血管内皮細胞インスリンシグナル障害はインスリン依存性の骨格筋の糖取り込み障害を惹起する2011

    • Author(s)
      窪田直人,窪田哲也,植木浩二郎,門脇孝
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] DPP-4阻害薬の2型糖尿病モデル動物に対する抗糖尿病作用2011

    • Author(s)
      中屋恵三,窪田直人,高本偉碩,窪田哲也,佐藤寛之,勝山修行,橋本信嗣,後藤守兄,城森孝仁,植木浩二郎,門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] インスリン感受性調節におけるインターロイキン33の役割について2011

    • Author(s)
      渡部拓,竹内倫徳,窪田直人,坂上慎二,後藤知紗,辻野一三,窪田哲也,三品昌美,門脇孝,西村正治
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1、IRS-2の役割2011

    • Author(s)
      窪田直人,窪田哲也,熊谷洋紀,井上真理子,渡部拓,西村正浩,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第84回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明脳特異的IRS-2欠損マウスを用いて2011

    • Author(s)
      井上真理子, 窪田直人, 窪田哲也, 熊谷洋紀, 河合智子, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第84回日本内分泌学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 1st International Conference on Immuno Metabolism2011

    • Author(s)
      門脇孝
    • Organizer
      Adiponectin and adiponectin receptors in insulin resistance and type2 diabetes
    • Place of Presentation
      Crete, Greese(招待講演)
    • Year and Date
      2011-09-19
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 糖尿病と病理Pathological aspects of diabetes2011

    • Author(s)
      門脇孝
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      神奈川県横浜市(招待講演)
    • Year and Date
      2011-04-29
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS1、IRS2の役割2011

    • Author(s)
      窪田直人,窪田哲也,熊谷洋紀,井上真理子,渡部拓,西村正治,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 骨格筋のインスリン感受性調節における血管内皮細胞のインスリンシグナルの役割の解明2011

    • Author(s)
      窪田哲也,窪田直人,熊谷洋紀,井上真理子,河合智子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第25回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて-2011

    • Author(s)
      井上真理子,窪田直人,窪田哲也,岩村智勝,佐藤寛之,林高則,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] プロスタサイクリン誘導体、ベラプロストナトリウムと低用量ピオグリタゾンの併用による糖尿病改善作用の検討2011

    • Author(s)
      熊谷洋紀、高橋雄大、窪田直人、窪田哲也、井上真理子、河合智子、門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 視床下部腹内側核(VMH)破壊肥満モデルではアディポネクチン(ADN)産生が充進する2011

    • Author(s)
      鈴木洋子,石塚典子,清水弘行,大坂寿雅,窪田直人,窪田哲也,門脇孝,井上修二
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Adiponectin action through AMPK2011

    • Author(s)
      Takashi Kadowaki
    • Organizer
      American Diabetes Association 71st Scientific Sessions
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて-2011

    • Author(s)
      井上真理子,窪田直人,窪田哲也,熊谷洋紀,河合智子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第25回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Role of PI3 kinase in type 2 diabetes2011

    • Author(s)
      門脇孝
    • Organizer
      New Aspect of Phospholipid Biology and Medical
    • Place of Presentation
      福岡県福岡市(招待講演)
    • Year and Date
      2011-11-15
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 肥満・インスリン分泌不全を呈する2型糖尿病モデル動物に対するDPP-4阻害薬の長期投与効果2011

    • Author(s)
      中屋恵三,佐藤寛之,窪田直人,高本偉碩,窪田哲也,勝山修行,橋本信嗣,後藤守兄,城森孝仁,植木浩二郎,門脇孝
    • Organizer
      第25回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 血管内皮細胞インスリンシグナル障害はインスリン依存性の骨格筋の糖取り込み障害を惹起する2011

    • Author(s)
      窪田哲也、窪田直人、熊谷洋紀、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Multiple aspects of molecular mechanism of insulin resistance in type2 diabetes2011

    • Author(s)
      Takashi Kadowaki
    • Organizer
      76th Cold Spring Harbor Laboratory Symposium
    • Place of Presentation
      Cold Spring Harbor, USA
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Impaired Insulin Signaling in the Endothelial Cells Reduces Insulininduced Glucose Uptake by the Skeletal Muscle2011

    • Author(s)
      Tetsuya Kubota, Naoto Kubota, Tomokatsu Iwamura, Marika Inoue, Hiroyuki Sate, Takanori Hayashi, Iseki Takamoto, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      The 16th Japan-Korea Symposium on Diabetes Mellitus
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞のTcf712は膵β細胞量維持に重要な役割を果たしている2011

    • Author(s)
      高本偉碩,窪田直人,中屋恵三,熊谷勝義,小畑淳史,勝山修行,窪田哲也,北村忠弘,植木浩二郎,門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] PGI2アナログは血管内皮細胞のインスリンシグナルを介して肥満モデルマウスの骨格筋のインスリン依存性糖取り込みを改善する2011

    • Author(s)
      窪田哲也、窪田直人、岩村智勝、井上真理子、佐藤寛之、高本偉碩、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第29回肥満症治療学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2011-06-10
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] インスリン感受性調節におけるインターロイキン33の役割について2011

    • Author(s)
      渡部拓,竹内倫徳,窪田直人,坂上慎二,後藤知紗,窪田哲也,西村正治,三品昌美,門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 災害時の糖尿病医療-日本糖尿病学会の対応と今後の対応2011

    • Author(s)
      門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会緊急シンポジウム「災害時の糖尿病医療」
    • Place of Presentation
      北海道札幌市
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Adiponectin & Adipose Tissue2011

    • Author(s)
      門脇孝
    • Organizer
      Endo 2011
    • Place of Presentation
      Boston, USA(招待講演)
    • Year and Date
      2011-06-05
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] The Effects of SK-o4os, a highly selective DPP-4 inhibitor, on(s-cell mass and function in haploinsufficiency of) s-cellspecific glucokinase mice on a high-fat diet2011

    • Author(s)
      Keizo Nakaya, Naoto Kubota, Iseki Takamoto, Tetsuya Kubota, Hisayuki Katsuyama, Hiroyuki Sate, Shinji Hashimoto, Moritaka Goto, Takahito Jomori, Kohjiro Ueki, and Takashi Kadowaki
    • Organizer
      71th American Diabetes Association's Scientific Sessions
    • Place of Presentation
      San diego, USA
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 生活習慣病からみた抗加齢医学2011

    • Author(s)
      門脇孝
    • Organizer
      第11回日本抗加齢医学会総会
    • Place of Presentation
      京都府京都市(招待講演)
    • Year and Date
      2011-05-28
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] チアゾリジン誘導体の抗動脈硬化作用におけるアディポネクチンの役割の解明2011

    • Author(s)
      窪田哲也、窪田直人、佐藤寛之、岩村智勝、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞のTcf712は膵β細胞量維持に重要な役割を果たしている2011

    • Author(s)
      高本偉碩,窪田直人,中屋恵三,熊谷勝義,小畑淳史,勝山修行,窪田哲也,植木浩二郎,門脇孝
    • Organizer
      第25回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Impaired insulin signaling in the endothelial cells reduces insulininduced glucose uptake by the skeletal muscle2011

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Marika Inoue, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      Scientific Sessions 71th American Diabetes Association
    • Place of Presentation
      San Diego
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞のTcf712は膵β細胞量維持に重要な役割を果たしている2011

    • Author(s)
      高本偉碩,窪田直人,小畑淳史,熊谷勝義,勝山修行,窪田哲也,北村忠弘,植木浩二郎,門脇孝
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Adiponectin action through AMPK2011

    • Author(s)
      門脇孝
    • Organizer
      American Diabetes Association 71st Scientific Sessions
    • Place of Presentation
      San Diego, USA(招待講演)
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて-2011

    • Author(s)
      井上真理子、窪田直人、窪田哲也、熊谷洋紀、河合智子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 視床下部腹内側核(VMH)破壊肥満モデルではアディポネクチン(ADN)産生が亢進する2011

    • Author(s)
      鈴木洋子, 石塚典子, 清水弘行, 大坂寿雅, 窪田直人, 窪田哲也, 門脇孝, 井上修二
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 我が国におけるウエスト周囲径・メタボリックシンドロームに関するエビデンス2011

    • Author(s)
      門脇孝
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫県淡路市(招待講演)
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle2011

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Mariko Inoue, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      Scientific Sessions 71th American Diabetes Association
    • Place of Presentation
      San Diego
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Insulin and adiponectin pathways in type2 diabetes2011

    • Author(s)
      門脇孝
    • Organizer
      Dundee Diabetes Research Centre Annual Lecture Seminar
    • Place of Presentation
      Dundee, Scotland(招待講演)
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 2型糖尿病の分子機構解明における遺伝子操作動物の意義2011

    • Author(s)
      門脇孝
    • Organizer
      第25回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] The Effects of SK-0403, a highly selective DPP-4 inhibitor, on β-cell mass and function in haploinsufficiency of β-cell-specific glucokinase mice on a high-fat diet2011

    • Author(s)
      Keizo Nakaya, Naoto Kubota, Iseki Takamoto, Tetsuya Kubota, Hisayuki Katsuyama, Hiroyuki Sato, Shinji Hashimoto, Moritaka Goto, Takahito Jomori, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      71th American Diabetes Association's Scientific Sessions
    • Place of Presentation
      San Diego
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 2型糖尿病の体質に関する研究-遺伝素因の解明とアディポネクチン作用低下の意義2011

    • Author(s)
      門脇孝
    • Organizer
      第61回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 2型糖尿病の分子機構と治療戦略2011

    • Author(s)
      門脇孝
    • Organizer
      第108回日本内科学会講演会
    • Place of Presentation
      神奈川県横浜市(招待講演)
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Impaired Insulin Signaling in the Endothelial Cells Reduces Insulin-induced Glucose Uptake by the Skeletal Muscle2011

    • Author(s)
      Tetsuya Kubota, Naoto Kubota, Tomokatsu Iwamura, Mariko Inoue, Hiroyuki Sato, Takanori Hayashi, Iseki Takamoto, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      The 16th Japan-Korea Symposium on Diabetes Mellitus
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Multiple aspects of molecular mechanism of insulin resistance in type 2 diabetes2011

    • Author(s)
      門脇孝
    • Organizer
      76th Cold Spring Harbor Laboratory Symposium
    • Place of Presentation
      Cold Spring Harbor, USA(招待講演)
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Role of adiponectin/AdipoR1 in skeletal muscle in mitochondrial biogenesis, exercise endurance and insulin sensitivity.2010

    • Author(s)
      Kadowaki T
    • Organizer
      The 14th International Congress of Endocrinology(ICE2010)
    • Place of Presentation
      京都
    • Year and Date
      2010-03-28
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Endothelial insulin signaling regulates capillary recruitment and glucose uptake in skeletal muscle2010

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Mariko Inoue, Tomoko Kawai, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      Scientific Sessions 70^<th> American Diabetes Association
    • Place of Presentation
      Orlando
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-l、IRS-2の役割2010

    • Author(s)
      窪田直人,窪田哲也,渡部拓,西村正治,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Role of Adiponectin and Adiponectin Receptors in Insulin Resistance2010

    • Author(s)
      門脇孝
    • Organizer
      The official Satellite Symposium of the 14^<th> ICE2010
    • Place of Presentation
      東京
    • Year and Date
      2010-03-25
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Adiponectin : a key Regulator of Diabetes and Cancer2010

    • Author(s)
      門脇孝
    • Organizer
      A symposium at Institute Pasteur Korea
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-02-19
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 膵島IRS-2量調節の分子機構:分子メカニズム2010

    • Author(s)
      大杉満、勝山修行、窪田直人、植木浩二郎、門脇孝
    • Organizer
      第3回日本肥満症治療学会学術集会
    • Place of Presentation
      東京(口頭発表)
    • Year and Date
      2010-09-11
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Presentation] 生活習慣病の成因・治療のエビデンスと管理栄養士の使命2010

    • Author(s)
      門脇孝
    • Organizer
      第13回日本病態栄養学会
    • Place of Presentation
      京都
    • Year and Date
      2010-01-09
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 膵島IRS-2量調節の分子機構2:分子メカニズム2010

    • Author(s)
      大杉満、勝山修行、窪田直人、植木浩二郎、門脇孝
    • Organizer
      第53回日本糖尿病学会学術総会
    • Place of Presentation
      岡山(口頭発表)
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Presentation] アディポネクチンの摂食・エネルギー代謝調節メカニズム2010

    • Author(s)
      窪田直人, 窪田哲也, 山内敏正, 植木浩二郎, 箕越靖彦, 門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-11
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肥満・インスリン分泌不全を呈する2型糖尿病モデル動物に対するDPP-4阻害薬の長期投与効果2010

    • Author(s)
      中屋恵三, 窪田直人, 高本偉碩, 窪田哲也, 勝山修行, 橋本信嗣, 後藤守兄, 城森孝仁, 植木浩二郎, 門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明脳特異的IRS-2欠損マウスを用いて2010

    • Author(s)
      井上真理子,窪田直人,窪田哲也,熊谷洋紀,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第83回日本内分泌学会術総会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵島IRS-2量調節の分子機構1:肥満・糖尿病モデルにおけるIRS-2量2010

    • Author(s)
      勝山修行、大杉満、窪田直人、植木浩二郎、門脇孝
    • Organizer
      第53回日本糖尿病学会学術総会
    • Place of Presentation
      岡山(口頭発表)
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Presentation] 糖と脂質代謝における肝IRS1とIRS2の生理学的・病態生理学的役割2010

    • Author(s)
      窪田直人, 窪田哲也, 熊谷裕紀, 井上真理子, 河合智子, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Rimonabant Ameliorates Insulin Resistance via both Adiponectin-dependent and Adiponectin-independent Pathways2010

    • Author(s)
      Naoto Kubota, Taku Watanabe, Tetsuya Kubota, Iseki Takamoto, Kohjiro Ueki, and Takashi Kadowaki
    • Organizer
      FASEB Summer Research Conference
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-l、IRS-2の役割2010

    • Author(s)
      窪田直人,窪田哲也,熊谷裕紀,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] DPP-4阻害薬の2型糖尿病モデル動物に対する長期投与効果の検討2010

    • Author(s)
      中屋恵三, 窪田直人, 高本偉碩, 窪田哲也, 勝山修行, 橋本信嗣, 後藤守兄, 城森孝仁, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵島IRS-2量調節の分子機構:肥満・糖尿病モデルにおけるIRS-2量2010

    • Author(s)
      勝山修行、大杉満、窪田直人、植木浩二郎、門脇孝
    • Organizer
      第3回日本肥満症治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-11
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Presentation] 骨格筋のインスリン感受性調節における血管内皮細胞のインスリンシグナルの役割の解明2010

    • Author(s)
      窪田哲也,窪田直人,熊谷洋紀,井上真理子,河合智子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 骨格筋のインスリン感受性調節における血管内皮細胞のインスリンシグナルの役割の解明2010

    • Author(s)
      窪田哲也,窪田直人,熊谷洋紀,井上真理子,河合智子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca2+ signalling and AMPK/SIRT1 like exercise.2010

    • Author(s)
      Yamauchi T, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
    • Organizer
      46^<th> Annual Meeting of the European Association for the Study of Diabetes.
    • Place of Presentation
      Stockholm
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Endothelial insulin signaling regulates capillary recruitment and glucose uptae in skeleal muse Scientific Sessions2010

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Mariko Inoue, Tomoko Kawai, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      70th American Diabetes Association
    • Place of Presentation
      Orlando
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Endothelial insulin signaling regulates capillary recruitment and glucose uptake in skeletal muscle2010

    • Author(s)
      Tetsuya Kubota, Naoto Kubota, Hiroki Kumagai, Mariko Inoue, Tomoko Kawai, Toshimasa Yamauchi, Kohjiro Ueki 1and Takashi Kadowaki
    • Organizer
      The 2nd Scientific Meeting of the Asian Association for the Study of Diabetes
    • Place of Presentation
      Okayama
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 血管内皮細胞のインスリンシグナルの糖代謝調節における役割の解明2010

    • Author(s)
      窪田哲也、窪田直人、熊谷洋紀、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第83回日本内分泌学会学術総会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Adiponectin and AdipoRl regulate PGC-lalpha and mitochondria by Ca^<2+> signalling and AMPK/SIRTl like exercise.2010

    • Author(s)
      Yamauchi T. Iwabu M. Okada-Iwabu M, Ueki K, Kadowaki T
    • Organizer
      6^<th>Annual Meeting of the European Association for the Study of Diabetes.
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 血管内皮細胞インスリンシグナルの糖代謝調節における役割の解明2010

    • Author(s)
      窪田直人,窪田哲也,門脇孝
    • Organizer
      第60回日本体質医学会総会
    • Place of Presentation
      熊本
    • Year and Date
      2010-10-16
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Endothelial insulin-induced eNOS activation regulates capillary ecruitment and glucos uptake in skeletal muscle2010

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Hiroki Kumagai, Toshimasa Yamauchi, Kohjiro Ueki and Takashi Kadowaki
    • Organizer
      8th International Diabetes Federation Western Pacific Region Congress
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Endothelial insulin signaling regulates glucose uptake by skeletal muscle2010

    • Author(s)
      Tetsuya Kubota, 1 Naoto Kubota, 1 Hiroki Kumagai1 Mariko Inoue, 1 Iseki Takamoto, 1 Toshimasa Yamauchi, 1 Kohjiro Ueki, 1 and Takashi Kadowaki
    • Organizer
      The 14th international congress of endocrinology
    • Place of Presentation
      Kyoto
    • Year and Date
      2010-03-30
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肥満・インスリン分泌不全を呈する2型糖尿病モデル動物に対するDPP-4阻害薬の長期投与効果2010

    • Author(s)
      中屋恵三, 窪田直人, 高本偉碩, 窪田哲也, 勝山修行, 橋本信嗣, 後藤守兄, 城森孝仁, 植木浩二郎, 門脇孝
    • Organizer
      第3回日本肥満症治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1、 IRS-2の役割2010

    • Author(s)
      窪田直人, 窪田哲也, 熊谷裕紀, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞のTcf712は膵β細胞量維持に重要な役割を果たしている2010

    • Author(s)
      高本偉碩, 窪田直人, 中屋恵三, 熊谷勝義, 勝山修行, 窪田哲也, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle2010

    • Author(s)
      窪田直人、窪田哲也、門脇孝
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] チアゾリジン誘導体の抗動脈硬化作用におけるアディポネクチンの役割の解明2010

    • Author(s)
      河合智子,窪田直人,窪田哲也,熊谷洋紀,井上真理子,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1、 IRS-2の役割2010

    • Author(s)
      窪田直人, 窪田哲也, 渡部拓, 西村正治, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第31回日本肥満学会
    • Place of Presentation
      群馬
    • Year and Date
      2010-10-01
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明 脳特異的IRS-2欠損マウスを用いて2010

    • Author(s)
      井上真理子, 窪田直人, 窪田哲也, 熊谷洋紀, 河合智子, 山内敏正, 植木浩二郎, 門脇孝
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて-2010

    • Author(s)
      井上真理子、窪田直人、窪田哲也、熊谷洋紀、山口真一、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第83回日本内分泌学会学術総会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1、IRS-2の機能的な役割分担2010

    • Author(s)
      窪田直人,窪田哲也,渡部拓,西村正治,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第83回日本内分泌学会学術総会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞にdominant negative型Tcf7l2を過剰発現させたマウスは耐糖能異常を呈する2009

    • Author(s)
      高本偉碩、窪田直人、中屋恵三、熊谷勝義、勝山修行、渡部拓、窪田哲也、植木浩二郎、宮崎純一、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Adipocyte2009

    • Author(s)
      門脇孝
    • Organizer
      20^<th> World Diabetes Congress(IDF)
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2009-10-20
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて2009

    • Author(s)
      井上真理子、窪田直人、窪田哲也、山口真一、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第46回日本臨床分子医学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-12
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肥満とアディポカイン-メタボリックシンドロームを理解する-2009

    • Author(s)
      門脇孝
    • Organizer
      第2回日本肥満症治療学会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-11
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 血管内皮特異的Akt/PKB欠損マウスの解析2009

    • Author(s)
      鈴木美穂、植木浩二郎、金子和真、窪田哲也、窪田直人、Morris Birnbaum、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The Rule of IRS2 in Hepatic Insulin Sensitivuty2009

    • Author(s)
      門脇孝
    • Organizer
      American Diabetes Association 69^<th> Scientific Sessions
    • Place of Presentation
      Louisiana, U.S.A.
    • Year and Date
      2009-06-06
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1,IRS-2の機能的な役割分担2009

    • Author(s)
      窪田直人、窪田哲也、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      浜松
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Epidemic of type 2 diabetes in Japan-Its causes and preventive strategies2009

    • Author(s)
      門脇孝
    • Organizer
      3^(rd) International Congress on Pre diabetes and the Metabolic Syndrome
    • Place of Presentation
      Nice, France
    • Year and Date
      2009-04-02
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] The physiological and pathophysiological roles of Insulin Receptor substrate 1and 2 in the regulation of glucose and lipid metabolism in the liver2009

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      The 15th Korea-Japan Symposium on Diabetes Mellitus
    • Place of Presentation
      Jeju Island
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Pioglitazone Ameliorates Cuff Induced Neointimal Formation by both Adiponectin Dependent and Independent Pathways.2009

    • Author(s)
      Tetsuya Kubota、Naoto Kubota、Iseki Takamoto, Masao Moroi, Kaoru Sugi, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      第41回日本動脈硬化学会年次学術集会
    • Place of Presentation
      山口
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵 β 細胞におけるインスリンシグナルの役割2009

    • Author(s)
      植木浩二郎、門脇孝
    • Organizer
      第23回 日本糖尿病・肥満動物学会年次学術集会シンポジゥム
    • Place of Presentation
      岡山
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] 骨格筋のインスリン感受性調節における血管内皮細胞のインスリンシグナルの役割の解明2009

    • Author(s)
      窪田哲也、窪田直人、熊谷洋紀、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第13回日本心血管内分泌学会
    • Place of Presentation
      大宮
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Pioglitazone Ameliorates Cuff Induced Neointimal Formation by both Adiponectin Dependent and Independent Pathways2009

    • Author(s)
      Tetsuya Kubota, Naoto Kubota, Iseki Takamoto, Masao Moroi, Kaoru Sugi, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      第41回日本動脈硬化学会年次学術集会
    • Place of Presentation
      山口
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 糖尿病体質とは 糖尿病の分子生物学の最前線 肝臓の糖・脂質代謝におけるIRS-1、IRS-2の機能的な役割分担2009

    • Author(s)
      窪田直人、窪田哲也、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第59回日本体質医学会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-25
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 中枢のIRS-2の糖代謝調節における役割の解明-脳特異的IRS-2欠損マウスを用いて2009

    • Author(s)
      井上真理子、窪田直人、窪田哲也、山口真一、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] インスリンシグナルの破綻と糖尿病 肝臓の糖・脂質代謝におけるIRS-1、IRS-2の役割2009

    • Author(s)
      窪田直人、窪田哲也、伊藤晋介、山内敏正、寺内康夫、戸辺一之、植木浩二郎、門脇孝
    • Organizer
      第82回日本内分泌学会学術総会
    • Place of Presentation
      前橋
    • Year and Date
      2009-04-23
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵島代償性増殖とその破綻における膵島IRS-2量調節の分子機構:糖代謝の重要性2009

    • Author(s)
      勝山修行、大杉満、窪田直人、戸邉一之、小林正稔、笹子敬洋、金子和真、植木浩二郎、門脇孝
    • Organizer
      第52回日本糖尿病学会学術総会
    • Place of Presentation
      大阪(口頭発表)
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Presentation] ゲノムワイド関連解析に基づく疾患の病態解明:糖尿病2009

    • Author(s)
      門脇孝
    • Organizer
      日本人類遺伝学会第54回大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17019047
  • [Presentation] The Rule of IRS2 in Hepatic Insulin Sensitivity.2009

    • Author(s)
      Kadowaki T
    • Organizer
      American Diabetes Association 69^<th> Scientific Sessions
    • Place of Presentation
      Louisiana
    • Year and Date
      2009-06-06
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 糖尿病患者の新たなる治療ステージ2009

    • Author(s)
      門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 食事中の脂肪酸組成が肥満やインスリン感受性・耐糖能に与える影響について2009

    • Author(s)
      内山弓子、門脇弘子、加藤美智子、井上真理子、窪田哲也、窪田直人、門脇孝
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      浜松
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 2型糖尿病の体質とそれをふまえた治療戦略2009

    • Author(s)
      門脇孝
    • Organizer
      日本体質医学会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-25
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 膵島代償性増殖とその破綻における膵島IRS-2量調節の分子機構:CaMキナーゼ4転写因子CREBの役割2009

    • Author(s)
      大杉満、窪田直人、戸邉一之、小林正稔、笹子敬洋、金子和真、勝山修行、植木浩二郎、門脇孝
    • Organizer
      第52回日本糖尿病学会学術総会
    • Place of Presentation
      大阪(口頭発表)
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Presentation] Adipocyte.2009

    • Author(s)
      Kadowaki T
    • Organizer
      20^<th> World Diabetes Congress(IDF)
    • Place of Presentation
      Montreal
    • Year and Date
      2009-10-20
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Class 1B PI3キナーゼ制御による肥満糖尿病治療の可能性の検討割2009

    • Author(s)
      植木浩二郎、小林直樹、門脇孝
    • Organizer
      第30回日本肥満学会シンポジウム(招待)
    • Place of Presentation
      浜松市
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21390278
  • [Presentation] Class 1B PI3キナーゼ制御による肥満糖尿病治療の可能性の検討割2009

    • Author(s)
      植木浩二郎、小林直樹、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会シンポジウム(招待)
    • Place of Presentation
      大阪市
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21390278
  • [Presentation] The physiological and pathophysiological roles of Insulin Receptor substrate 1 and 2 in the regulation of glucose and lipid metabolism in the liver2009

    • Author(s)
      Naoto Kubota、Kubota T、Toshimasa Yamauchi、Kohjiro Ueki、Kadowaki T
    • Organizer
      The 15th Korea-Japan Symposium on Diabetes Mellitus
    • Place of Presentation
      Jeju Island
    • Year and Date
      2009-11-19
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 肥満糖尿病におけるClass IB PI3キナーゼの役割2009

    • Author(s)
      植木浩二郎、小林直樹、門脇孝
    • Organizer
      第82回日本内分泌学会学術総会シンポジウム(公募)
    • Place of Presentation
      前橋市
    • Year and Date
      2009-04-23
    • Data Source
      KAKENHI-PROJECT-21390278
  • [Presentation] 血管内皮細胞インスリンシグナルの糖代謝調節における役割の解明2009

    • Author(s)
      窪田哲也、窪田直人、山口真一、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] IRS-2欠損膵β細胞株の樹立2009

    • Author(s)
      中屋恵三、高本偉碩、窪田直人、熊谷勝義、勝山修行、渡部拓、窪田哲也、植木浩二郎、宮崎純一、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵島代償性増殖とその破綻における膵島IRS-2量調節の分子機構2009

    • Author(s)
      大杉満、窪田直人、小林正稔、笹子敬洋、金子和真、勝山修行、植木浩二郎、門脇孝
    • Organizer
      第59回日本体質医学会総会
    • Place of Presentation
      東京(口頭発表)
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Presentation] 抗肥満薬リモナバンのインスリン抵抗性改善機構について2009

    • Author(s)
      渡部拓、窪田直人、大杉満、窪田哲也、高本偉碩、窪田哲也、山内敏正、寺内康夫、戸辺一之、植木浩二郎、門脇孝
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      浜松
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Epidemic of type 2 diabetes in Japan-Its causes and preventive strategies.2009

    • Author(s)
      Kadowaki T
    • Organizer
      3^<rd> International Congress on Prediabetes and the Metabolic Syndrome.
    • Place of Presentation
      Nice
    • Year and Date
      2009-04-02
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] The physiological and pathophysiological roles of Insulin Receptor substrate 1 and 2 in the regulation of glucose and lipid metabolism in the liver2009

    • Author(s)
      Naoto Kubota、Kubota T、Toshimasa Yamauchi、Kohjiro Ueki, Kadowaki T, The 15th Congress of the ASEAN Federation of Endocrine Societies
    • Organizer
      The 15th Congress of the ASEAN Federation of Endocrine Societies
    • Place of Presentation
      Bangkok
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] インスリン感受性調節における血管内皮細胞インスリンシグナルの役割2009

    • Author(s)
      窪田直人,窪田哲也,山口真一,山内敏正,槙木浩二郎,門脇孝
    • Organizer
      第23回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2009-02-13
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] Inflammation and the Metabolic Syndrome2009

    • Author(s)
      門脇孝
    • Organizer
      Asia Pacific Conference on the Metabolic Syndrome
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2009-11-21
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 抗肥満薬リモナバンのインスリン抵抗性改善機構にはアディポネクチンに依存的なパスウェイと非依存的なパスウェイがある2009

    • Author(s)
      渡部拓、窪田直人、窪田哲也、大杉満、高本偉碩、山内敏正、寺内康夫、戸辺一之、植木浩二郎、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The physiological and pathophysiological role ofInsulin Receptor substrate 1 and 2 in the regulation of glucose and lipid metabolism in the liver2009

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      The 15th Congress of the ASEAN Federation of Endocrine Societies
    • Place of Presentation
      Bangkok
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 糖尿病ガイドライン:治療の面から2009

    • Author(s)
      門脇孝
    • Organizer
      第57回日本心臓学会学術集会
    • Place of Presentation
      北海道
    • Year and Date
      2009-09-20
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 膵β細胞におけるインスリンシグナルの役割2009

    • Author(s)
      植木浩二郎、門脇孝
    • Organizer
      第23 回 日本糖尿病・肥満動物学会年次学術集会シンポジウム
    • Place of Presentation
      岡山
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] 発生工学的研究を用いた糖尿病創薬研究の戦略2009

    • Author(s)
      門脇孝
    • Organizer
      第56回日本実験生物学会総会
    • Place of Presentation
      埼玉
    • Year and Date
      2009-05-14
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 血管内皮細胞におけるインスリン受容体基質(IRS)2の役割の解明-血管内皮細胞特異的IRS2欠損マウスを用いて-2009

    • Author(s)
      窪田哲也,窪田直人,山口真一,井上真理子,植木浩二郎,門脇孝
    • Organizer
      第23回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2009-02-13
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] Class 1B PI3キナーゼ制御による肥満糖尿病治療の可能性の検討割2009

    • Author(s)
      植木浩二郎、小林直樹、門脇孝
    • Organizer
      第82回日本生化学会大会シンポジウム(招待)
    • Place of Presentation
      神戸市
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-21390278
  • [Presentation] 糖尿病・メタボリックシンドロームの病態と治療戦略-最近の知見-2009

    • Author(s)
      門脇孝
    • Organizer
      第46回日本臨床分子医学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-12
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 肝臓の糖・脂質代謝におけるIRS-1, IRS-2の機能的な役割分担2009

    • Author(s)
      窪田直人,窪田哲也,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第30回日本肥満学会
    • Place of Presentation
      浜松
    • Year and Date
      2009-10-09
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] アディポサイトカインと心血管内分泌代謝学2009

    • Author(s)
      門脇孝
    • Organizer
      第13回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      埼玉
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 血管内皮細胞のインスリンシグナルの糖代謝調節における役割の解明2009

    • Author(s)
      窪田哲也、窪田直人、熊谷洋紀、井上真理子、山内敏正、植木浩二郎、門脇孝
    • Organizer
      第59回日本体質医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-26
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] The role of adiponectin in the CNS in the regulation of energy homoeostasis2009

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Kohjiro Ueki, Toshimasa Yamauchi, Minokoshi Yasuhiko, Takashi Kadowaki
    • Organizer
      Satellite Symposium of the 9th International Symposium on VIP, PACAP and Related Peptides
    • Place of Presentation
      Yakushima
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 遺伝子操作動物を用いた糖尿病研究の戦略2009

    • Author(s)
      門脇孝
    • Organizer
      第23回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2009-02-13
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] The role of adiponectin in the CNS in the regulation of energy homoeostasisi2009

    • Author(s)
      Naoto Kubota, Tetsuya Kubota, Kohjiro Ueki, Toshimasa Yamauchi, Minokoshi Yasuhiko, Takashi Kadowaki
    • Organizer
      Satellite Symposium of the 9th International Symposium on VIP, PACAP and Related Peptides
    • Place of Presentation
      Yakushima
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] 膵β細胞にdominant negative型Tcf712を過剰発現させたマウスは耐糖能異常を呈する2009

    • Author(s)
      高本偉碩、窪田直人、中屋恵三、熊谷勝義、勝山修行、渡部拓、窪田哲也、植木浩二郎、宮崎純一、門脇孝
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] アディポネクチンの摂食・エネルギー調節における役割2009

    • Author(s)
      窪田直人、窪田哲也、山内敏正、植木浩二郎、箕越靖彦、門脇孝
    • Organizer
      第62回日本自律神経学会
    • Place of Presentation
      和歌山
    • Year and Date
      2009-11-06
    • Data Source
      KAKENHI-PROJECT-21591156
  • [Presentation] Insulin signaling defect in endothelial cells causesskeletal muscle insulin resistance2008

    • Author(s)
      Kubota N, Kubota T, Kumagai H, Yamauchi T, Ueki K, Kadowaki T
    • Organizer
      第40回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      茨城
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] GlucoseEB-IR Pathway isponsible for the Failure of Compensatory β Hyperplasia in the Pogression to Diabetes.2008

    • Author(s)
      Mitsuru Ohsugi, Naoto Kubota, Kohjiro Ueki, Takashi Kadowaki
    • Organizer
      American Diabetes Association Annual Scientific Sessions
    • Place of Presentation
      San Francisco, CA, USA(Oral Presentation)
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-20591051
  • [Presentation] AMPK in sickness and health from molecule to man2008

    • Author(s)
      門脇孝
    • Organizer
      FASEB SUMMER RESEARCH CONFERENCES
    • Place of Presentation
      Copenhagen
    • Year and Date
      2008-08-14
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding2008

    • Author(s)
      Kubota N, Kubota T, Itoh S Terauchi Y,Ueki K, Kadowaki T
    • Organizer
      Scilentific Sessions 68th American Diabetes Association
    • Place of Presentation
      San Frandisco
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] 2型の糖尿病の成因を追い求める旅」-真理への希求-2008

    • Author(s)
      門脇孝
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 抗肥満薬RimonabantにおけるAdiponectinの役割2008

    • Author(s)
      渡辺拓,窪田直人,窪田哲也,大杉満,戸辺一之,門脇孝
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] Insulin signaling in endothelial cells participates in the regulation of skeletal muscle insulin sensitivity2008

    • Author(s)
      Kubota T, Kubota N, Yamaguchi S, Inoue M, Veki K, Kadowaki T
    • Organizer
      The 10th Symposium on Molecular Diabetology in Asia
    • Place of Presentation
      Guangzhou
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008

    • Author(s)
      Kubota N, Kubota T, Yamauchi T, Ueki K, Kadowaki T
    • Organizer
      The 4th Scientific Meeting of Asia-Pacific Diabetes and Obesity Study Group
    • Place of Presentation
      Japan(Osaka)
    • Year and Date
      2008-08-20
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] 糖尿病食事関連QOL尺度改訂版の短縮版開発に向けてDelphi法を用いた検討2008

    • Author(s)
      佐藤栄子,沢丞,柴山大賀,西垣昌和,落合亮太,鈴鴨よしみ,門脇孝,数間恵子
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京・東京国際フォーラム
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PROJECT-19390555
  • [Presentation] Adiponectin and its receptors in insulin resistance, diabetes and metabolic syndrome and obesity2008

    • Author(s)
      門脇孝
    • Organizer
      10^<th> European Congress of Endocrinology
    • Place of Presentation
      berlin
    • Year and Date
      2008-05-06
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Role of Class 1A PI3 kinase in pancreatic beta cells2008

    • Author(s)
      金子和真、植木浩二郎、門脇孝
    • Organizer
      第68回アメリカ糖尿病学会 (oral session)
    • Place of Presentation
      サンフランシスコ
    • Year and Date
      2008-06-08
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] 肝臓の糖代謝におけるIRS-1、IRS-2の役割の検討2008

    • Author(s)
      窪田直人,窪田哲也,伊藤晋介,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第13回アディポサイエンス研究会
    • Place of Presentation
      大阪
    • Year and Date
      2008-08-22
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] Insulin signaling in endothelial cells participates in the regulation of skeletal muscle insulin sensitivity2008

    • Author(s)
      Kubota T, Kubota N, Kozono H, Takahashi T, Itoh S, Ueki K, Kadowaki T
    • Organizer
      Scientific Sessions 68th American Diabetes Association
    • Place of Presentation
      San Francisco
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008

    • Author(s)
      Kubota N, Kubota T, Yamauchi T, Ueki K, Kadowaki T
    • Organizer
      The 1st Insulin Resistance in Metabolic Disease Forum
    • Place of Presentation
      Japan(Osaka)
    • Year and Date
      2008-09-20
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] 膵β細胞におけるClass IA PI3キナーゼの役割2008

    • Author(s)
      金子和真、植木浩二郎、門脇孝
    • Organizer
      第51回日本糖尿病学会年次学術集会 (oral session)
    • Place of Presentation
      東京
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] 膵β細胞におけるClass IA PI3 キナーゼの役割2008

    • Author(s)
      金子和真、植木浩二郎、門脇孝
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京(oral session)
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] インスリン抵抗性とメタボリックシンドローム2008

    • Author(s)
      窪田直入,門脇孝
    • Organizer
      第6回徳島大学疾患酵素研究センターシンポジウム
    • Place of Presentation
      徳島
    • Year and Date
      2008-12-05
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] Role of Class 1A PI3 kinase in pancreatic beta cells2008

    • Author(s)
      金子和真、植木浩二郎、門脇孝
    • Organizer
      第68回アメリカ糖尿病学会
    • Place of Presentation
      サンフランシスコろ(oral session)
    • Year and Date
      2008-06-08
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] IRS-2欠損膵β細胞株の樹立2008

    • Author(s)
      高本偉碩,窪田直人,橋本信嗣,峯山智佳,窪田哲也,伊藤晋介,山内敏正,植木浩二郎,宮崎純一,門脇孝
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] メタボリック症候群とアディボカイン2008

    • Author(s)
      門脇孝
    • Organizer
      第51回日本腎臓学会学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-06-01
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] インスリン抵抗性発症における血管と骨格筋のネットワーク機構の解明2008

    • Author(s)
      窪田哲也,窪田直人,熊谷洋紀,小園秀樹,高橋雄大,杉薫,山内敏正,植木浩二郎,門脇孝
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PROJECT-19591037
  • [Presentation] Exocytosis Complex Molecules Rab3 and SNAP25 in Islet β cells in Response to Systemic Insulin Resistance and Glucotoxicity2007

    • Author(s)
      Kobayashi M, Tobe K, Suzuki R, Ohsugi M, Kowatari-Otsuka N, Sakamoto K Kubota N, Terauchi Y, Nagamatsu S, and Kadowaki T
    • Organizer
      49th Annual Scientific Meeting of the Japan Diabetes Society
    • Place of Presentation
      Tokyo, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] メタボリックシンドロームアディポネクチン/AdipoRの病態生理的意義2007

    • Author(s)
      山内 敏正, 原一 雄, 窪田 直人, 植木浩 二郎, 戸辺 一之, 門脇 孝
    • Organizer
      第44回日本臨床分子医学会学術総会
    • Place of Presentation
      和歌山
    • Year and Date
      2007-07-20
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Presentation] Pathophysiological Role of Vagal Anti-inflammatory Pathway via α7-Nicotinic Receptors in Experimental Ulcerative Colitis.2007

    • Author(s)
      Kadowaki M.
    • Organizer
      5th Congress of the International Society for Autonomic Neuroscience.
    • Place of Presentation
      Kyoto
    • Year and Date
      2007-10-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590507
  • [Presentation] Pathophysiological Role of Vagal Anti-inflammatory Pathway via α7-Nicotinic Receptors in Experimental Ulcerative Colitis2007

    • Author(s)
      Kadowaki, M
    • Organizer
      5th Congress of the International Society for Autonomic Neuroscience
    • Place of Presentation
      Kyoto
    • Year and Date
      2007-10-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590507
  • [Presentation] Cholinergic anti-inflammatory pathway through α7-nicotinic acetylcholine receptors in the colon reduces oxazolone-induced colitis in mouse.2007

    • Author(s)
      Kadowaki M.
    • Organizer
      Falk Workshop"Mechanisms of Intestinal Inflammation"
    • Place of Presentation
      Dresden, Germany.
    • Year and Date
      2007-10-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590507
  • [Presentation] Critical Roles of IRS-1 and IRS-2 in the Development of Fetal Pancreatic Islets2007

    • Author(s)
      Ohsugi M, Tobe K, Suzuki R, Kowatari-Otsuka N, Kubota N, Terauchi Y, and 10th Annual Kadowaki T
    • Organizer
      Scientific Meeting of Japan Society of Metabolism and Clinical Nutrition
    • Place of Presentation
      Yokohama, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] Mice Overexpressing Monocyte Chemoattract Protein 1(MCP-1) in Adipose Tissues Exhibit Insulin Resistance in the Skeltal Muscle2007

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Sakamoto K, Kobayashi M, Kowatari-Otsuka N, Kubota N, and Kadowaki T.
    • Organizer
      49th Annual Scientific Meeting of the Japan Diabetes Society
    • Place of Presentation
      Tokyo, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] Cholinergic anti-inflammatory pathway through α7-nicotinic acetylcholine receptors in the colon reduces oxazolone-induced colitis in mouse2007

    • Author(s)
      Kadowaki, M
    • Organizer
      Falk Workshop "Mechanisms of Intestinal Inflammation"
    • Place of Presentation
      Dresden, Germany
    • Year and Date
      2007-10-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590507
  • [Presentation] Islet IRS-2 Increases in Response to Systemic Insulin Resistance2007

    • Author(s)
      Ohsugi M, Tobe K, Kobayashi M, Suzuki R, Sasako T, and Kadowaki T
    • Organizer
      50th Annual Scientific Meeting of the Japan Diabetes Society
    • Place of Presentation
      Sendai, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] Pathophysiological roles of Adiponectin and Adiponectin Receptors2007

    • Author(s)
      Toshmasa Yamauchi, Naoto Kubota, Kazuo Hara, Kohjio Ueki, Kazuyuki Tobe and Takashi Kadowaki
    • Organizer
      Okazaki Symposium 2007 on Obesity & Diabetes
    • Place of Presentation
      Okazaki
    • Year and Date
      2007-04-14
    • Data Source
      KAKENHI-PROJECT-18390270
  • [Presentation] Chohnergic anti-inflammatory pathway through α7-nicotinic acetylcholinle receptors in the colon reduces oxazolone-induced colitis in mouse2007

    • Author(s)
      Kadowaki M.
    • Organizer
      Falk workshop "Mechaisms of Intestinal lnflammation"
    • Place of Presentation
      Dresden, Germany
    • Year and Date
      2007-10-09
    • Data Source
      KAKENHI-PROJECT-18590507
  • [Presentation] Pathophysiological Role of Vagal Anti-inflammatory Pathway via α7-Nicotinic Receptors in Experimental Ulcerative Colitis.2007

    • Author(s)
      Kadowaki M.
    • Organizer
      5th Congress of the International Society for Autonomic Neuroscience.
    • Place of Presentation
      京都
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-18590507
  • [Presentation] 膵β細胞におけるClass IA PI3 キナーゼの役割2007

    • Author(s)
      金子和真、植木浩二郎、門脇孝
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台(oral session)
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] Role of Class 1A PI3 kinase in pancreatic beta cells2007

    • Author(s)
      金子和真、植木浩二郎、門脇孝
    • Organizer
      第67回アメリカ糖尿病学会
    • Place of Presentation
      シカゴ(oral session)
    • Year and Date
      2007-06-24
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] Pathophysiological roles of Adiponectin and Adiponectin Receptors2007

    • Author(s)
      Toshimasa Yamauchi, Naoto Kubota, Kazuo Hara, Kohjiro Ueki, Kazuyuki Tobe, Takashi Kadowaki
    • Organizer
      Okazaki Symposium 2007 on Obesity & Diabetes
    • Place of Presentation
      Okazaki
    • Year and Date
      2007-04-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15081202
  • [Presentation] 膵β細胞におけるClass IA PI3キナーゼの役割2007

    • Author(s)
      金子 和真、植木 浩二郎、門脇 孝
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] Role of Class 1A PI3 kinase in pancreatic beta cells2007

    • Author(s)
      金子 和真、植木 浩二郎、門脇 孝
    • Organizer
      第67回アメリカ糖尿病学会
    • Place of Presentation
      シカゴ
    • Year and Date
      2007-06-22
    • Data Source
      KAKENHI-PROJECT-19390247
  • [Presentation] Mice Overexpressing Monocyte Chemoattract Protein 1(MCP-1) in Adipose Tissues Exhibit Whole Body Insulin Resistance2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Kubota N, and Kadowaki T.
    • Organizer
      American Diabetes Association Annual Scientific Sessions, Washington DC
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] 2型糖尿病の分子機構-インスリンとアディポネクチン作用を中心に

    • Author(s)
      門脇 孝
    • Organizer
      第85回日本内分泌学会学術総会
    • Place of Presentation
      名古屋
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 糖尿病と炎症

    • Author(s)
      門脇 孝
    • Organizer
      第33回日本炎症・再生医学会
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 合併症抑制をめざす糖尿病の治療戦略

    • Author(s)
      門脇 孝
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本県熊本市
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253068
  • [Presentation] Diet Therapy in Diabetes

    • Author(s)
      Takashi Kadowaki
    • Organizer
      8th Asia Pacific conference on Clinical Nutrition
    • Place of Presentation
      Chiba
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] 糖尿病と炎症-歯周病を含めて

    • Author(s)
      門脇 孝
    • Organizer
      第55回秋季日本歯周病学会学術大会
    • Place of Presentation
      茨城
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Molecular Mechanism of Insulin Resistance in Type 2 Diabetes

    • Author(s)
      Takashi Kadowaki
    • Organizer
      9th IDF-WPR Congress
    • Place of Presentation
      Kyoto, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Molecular Mechanism of Type 2 Diabetes

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Lecture in the Feinberg School of Medicine of Northwestern University
    • Place of Presentation
      Chicago, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 糖尿病と炎症

    • Author(s)
      門脇 孝
    • Organizer
      第77回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] AdipoRs Activation Reduced Ectopic Fat Accumulation and Inflammation, Leading to Improved Glucose/ Lipid Metabolism

    • Author(s)
      Takashi Kadowaki
    • Organizer
      The 64th FUJIHARA SEMINAR International Symposium on Adiponectin Biology and Medicine
    • Place of Presentation
      Tomakomai, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] The role of adiponectin and adiponection receptor in obesity-associated diseases

    • Author(s)
      門脇 孝
    • Organizer
      CSH (Cold Spring Harbor ) Asia Meeting
    • Place of Presentation
      Suzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253068
  • [Presentation] Impaired adiponectin receptor signaling in obesity-linked insulin resistance and shortened lifespan

    • Author(s)
      Takashi Kadowaki
    • Organizer
      International Symposium on Insulin Receptors and Insulin Action
    • Place of Presentation
      Barcelona, Spain
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] 若手医師のための糖尿病講義

    • Author(s)
      門脇 孝
    • Organizer
      第47回糖尿病学の進歩
    • Place of Presentation
      四日市
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Molecular Mechanism of Type 2 Diabetes

    • Author(s)
      Takashi Kadowaki
    • Organizer
      2012 Kroc Lecture
    • Place of Presentation
      Chicago, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] アディポネクチンを中心とした抗加齢戦略

    • Author(s)
      門脇 孝
    • Organizer
      日本抗加齢医学会主催エデュケーショナルセミナー
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Tofogliflozin, a Novel and Selective SGLT2 Inhibitor Improves Glycemic Control and Lowers Body Weight in Patients with Type 2 Diabetes Mellitus Inadequately Controlled on Stable Metformin or Diet and Exercise Alone

    • Author(s)
      Takashi Kadowaki
    • Organizer
      American Diabetes Association 72st Scientific Sessions
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 肥満に伴うインスリン抵抗性、2型糖尿病の分子機構に関する研究

    • Author(s)
      門脇 孝
    • Organizer
      第34回日本肥満学会年次学術集会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] Adiponectin in the development of type 2 diabetes

    • Author(s)
      Takashi Kadowaki
    • Organizer
      World Diabetes Congress 2013
    • Place of Presentation
      Melbourne, Australia
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] Roles of adiponectin receptors in regulation of nutrient disposal and promising drug target for obesity-linked disease

    • Author(s)
      Takashi Kadowaki
    • Organizer
      1st Annual Helmholtz-Nature Medicine Diabetes Conference
    • Place of Presentation
      Munich, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] A novel and Selective SGLT2 inhibitor, tofogliflozin improves glycemic control and lowers body weight in patients with type 2 diabetes mellitus

    • Author(s)
      Takashi Kadowaki
    • Organizer
      9th IDF-WPR Congress
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] 2型糖尿病の分子基盤-真理の探究

    • Author(s)
      門脇 孝
    • Organizer
      第8回臨床分子医学研究会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Dysregulation of signal transduction systems underlying intractable disorders

    • Author(s)
      Takashi Kadowaki
    • Organizer
      40th IMSUT Founding Commemorative Symposium
    • Place of Presentation
      Tokyo
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] Molecular Mechanism of Type 2 Diabetes

    • Author(s)
      門脇 孝
    • Organizer
      ISPAD Science School for Physicians 2012 in Kyoto Special Lecture
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] The role of adiponectin receptor in insulin resistance and type 2 diabetes

    • Author(s)
      Takashi Kadowaki
    • Organizer
      Boston Joslin International Symposium on Diabetes 2013
    • Place of Presentation
      Boston, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221307
  • [Presentation] 糖尿病学のすすめ-理事長からのメッセージ-

    • Author(s)
      門脇 孝
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本県熊本市
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253068
  • [Presentation] AdipoRs activation increases Ca2+and AMPK/SIRT/PGC-1, thereby regulating metabolic stress and mitochondria, leading to anti-aging and amelioration of diseases of aging

    • Author(s)
      Takashi Kadowaki
    • Organizer
      KEYSTONE SYMPOSIA: Aging and Diseases of Aging
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-20229008
  • [Presentation] Role of adiponectin receptors in type 2 diabetes and metabolic syndrome

    • Author(s)
      門脇 孝
    • Organizer
      40th IMSUT Founding Commemorative Symposium
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253068
  • []

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  • 1.  TOBE Kazuyuki (30251242)
    # of Collaborated Projects: 35 results
    # of Collaborated Products: 46 results
  • 2.  YAMAUCHI Toshimasa (40372370)
    # of Collaborated Projects: 31 results
    # of Collaborated Products: 243 results
  • 3.  TERAUCHI Yasuo (40359609)
    # of Collaborated Projects: 21 results
    # of Collaborated Products: 4 results
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    # of Collaborated Projects: 21 results
    # of Collaborated Products: 294 results
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    # of Collaborated Projects: 12 results
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  • 8.  KABURAGI Yasushi
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 7 results
    # of Collaborated Products: 4 results
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    # of Collaborated Projects: 6 results
    # of Collaborated Products: 55 results
  • 11.  TAMAMOTO Hiroyuki
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    # of Collaborated Products: 54 results
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    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 15.  佐倉 宏 (70240710)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 16.  KUBOTA Tetsuya (60385698)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 84 results
  • 17.  NAKAMURA Kozo (60126133)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 18.  KAWAGUCHI Hiroshi (40282660)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 19.  小田原 雅人 (00224254)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  MORI Yasumichi
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 21.  OHSUGI Mitsuru (00420216)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 26 results
  • 22.  NANJO Kishio (40164511)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 23.  KAZUMA Keiko (10114258)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  SUZUKI Ryo (20396732)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 26.  NODA Mitsuhiko (90237850)
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  • 27.  横野 浩一 (50144580)
    # of Collaborated Projects: 2 results
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  • 42.  TAKENAKA Katsu (20188204)
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  • 67.  玉岡 晃 (50192183)
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  • 78.  山下 滋雄
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  • 80.  小林 篤樹
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  • 81.  江頭 一弘
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  • 82.  SHOJIMA Nobuhiro
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  • 83.  ASAKAWA Akihiro
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  • 86.  TANAKA Hideo
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  • 87.  KUBO Michiaki
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  • 88.  MATSUDA Koichi
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  • 91.  SHIGETOMO Suyama
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  • 92.  NISHIMURA Satoshi
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  • 93.  TAKANO Katsura
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  • 94.  三木 隆司
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  • 95.  黒川 峰夫
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  • 96.  脇 裕典
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  • 97.  石垣 泰
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  • 98.  佐伯 武頼
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  • 99.  油谷 浩幸
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  • 100.  塩田 清二
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  • 101.  平子 哲史
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  • 102.  桜井 賛孝
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  • 104.  森 満
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  • 105.  中村 卓郎
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  • 106.  中村 祐輔
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  • 107.  高橋 悟
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  • 108.  高橋 隆
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  • 109.  野田 哲生
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  • 110.  今井 浩三
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    # of Collaborated Products: 1 results
  • 111.  田中 恵太郎
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    # of Collaborated Products: 1 results
  • 112.  田中 祐吉
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    # of Collaborated Products: 1 results
  • 113.  田中 勇悦
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    # of Collaborated Products: 1 results
  • 114.  中村 直哉
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    # of Collaborated Products: 1 results
  • 115.  戸田 郷太郎
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    # of Collaborated Products: 1 results
  • 116.  荒木 栄一
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    # of Collaborated Products: 1 results
  • 117.  熊谷 英敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 118.  池田 祐一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 119.  今村 美菜子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 120.  橋本 唯史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 121.  菅原 真衣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 122.  清水 孝雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 123.  磯 博康
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 124.  山岸 良匡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 125.  野田 愛(池田愛)
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 126.  斉藤 功
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 127.  矢田 俊彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 128.  中務 邦雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 129.  長崎 実佳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 130.  森山 光章
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 131.  中村 洋一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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