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KAI HIROFUMI  甲斐 広文

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… Alternative Names

Kai Hirofumi  甲斐 広文

KAI Hirofumi  甲斐 広文

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Researcher Number 30194658
Other IDs
External Links
Affiliation (Current) 2025: 熊本大学, 薬学部, 客員教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 熊本大学, 薬学部, 客員教授
2019 – 2022: 熊本大学, 大学院生命科学研究部附属グローバル天然物科学研究センター, 教授
2012 – 2016: 熊本大学, 大学院生命科学研究部(薬), 教授
2015: 熊本大学, 大学院生命科学研究部, 教授
2012: 熊本大学, 大学院生命科学研究部, 教授 … More
2009 – 2012: Kumamoto University, 大学院・生命科学研究部, 教授
2011: 熊本大学, 生命科学研究部, 教授
2009: Kumamoto University, 大学院・生命科学研究科, 教授
2007 – 2008: Kumamoto University, Graduate School Of Medical Sciences, Professor
2005 – 2006: 熊本大学, 大学院医学薬学研究部, 教授
2002 – 2005: Kumamoto University, Graduate School of Pharmaceutical Sciences, Department of Molecular Medicine, Professor, 大学院・医学薬学研究部, 教授
2002: 熊本大学, 大学院・薬学研究科, 教授
2001 – 2002: 熊本大学, 薬学研究科, 教授
2001 – 2002: 熊本大学, 薬学部, 教授
1997 – 2000: 熊本大学, 薬学部, 助教授
1994 – 1996: 熊本大学, 薬学部, 助手
1987 – 1992: 熊本大学, 薬学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological Sciences / Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related / Biomedical engineering/Biomaterial science and engineering / Applied pharmacology / Pharmacology in pharmacy / Biological Sciences / Biomedical engineering/Biological material science / Biological pharmacy / Medical pharmacy / 応用薬理学・医療系薬学 … More
Except Principal Investigator
… More Biological pharmacy / 応用薬理学・医療系薬学 / Medical pharmacy / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / Neurology / Biological pharmacy / 医薬分子機能学 / Physical pharmacy / Biological Sciences / General pharmacology Less
Keywords
Principal Investigator
CFTR / MEF / 小胞体 / calnexin / transthyretin / FAP / 分子シャペロン / lysozyme / ETS / 遺伝病 … More / cystic fibrosis / calreticulin / カルネキシン / 嚢胞性線維症 / IV型コラーゲン / Alport症候群 / 創薬 / Ⅳ型コラーゲン / アルポート症候群 / GM-CSF / EPITHELIUM / 物理療法 / ERAD / HRD / derlin / BiP / 小胞体関連分解(ERAD) / 家族性アミロイドポリニューロパチー(FAP) / ENaC / アミロイド / mucin / phosphatidic acid / タンパク質 / 薬理学 / toll-like receptor / 嚢胞性線維症(CF) / 遺伝性疾患 / 小胞体品質管理機構 / 自然免疫 / epithelium / 上皮細胞 / collagen / モデルマウス / Alisporivir / ミスセンス変異 / CKD / type 4 collagen / alport / kidney / 表現型 / 遺伝子型 / Split NanoLuciferase / Type IV collagen / 免疫抑制 / 免疫制御 / アルツハイマー病 / ETS transcription factor / PML nuclear body / molecular chaperone / heat shock protein / vitamin K / Heat Shock Protein / ガン / ガン抑制遺伝子 / 温熱療法 / クルクミン / カルレティキュリン / ETS-2 / LYSOZYME / アポトーシス / 肺胞上皮細胞 / 転写因子 / 分化 / 気道上皮細胞 / 糖尿病 / トランスサイレチン / アミロイドーシス / 家族性アミロイドポリニューロパチー / 化合物ライブラリースクリーニング / 慢性腎臓病 / p53 / ポドサイト / 脂質ラフト / 物理的ストレス / 糖尿病腎症 / インスリン受容体 / ラフト構造 / TRP family / 微弱電流 / amyloidosis / 小胞体局在化 / Transthvretin(TTR) / transthyretin(TTR) / calnexin(CNX) / aggresome / ER分子シャペロン / caveolae / endocytosis / Calreticulin(CRT) / Calnexin(CNX) / DNAメチル化 / 嚢胞性繊維症(CF) / Toll-like receptor (TLR) / transcription factor / ets / oncogene / differentiation / Airway / ガン遺伝子 / 転写制御因子 / 遺伝子発現 / 気道 / 糖蛋白 / 粘液 … More
Except Principal Investigator
siRNA / ピペリジン / シクロデキストリン / デンドリマー / CD36 / マクロファージ / グリベンクラミド / イオントフォレシス / 結合体 / GM-CSF / 肺胞上皮細胞 / MEF / 上皮細胞 / ACAT / 気道 / スカベンジャー受容体 / 光アフィニティラベル / FAP / carrier / デリバリー / キャリア / COPD / conjugate / dendrimer / cyclodextrin / グリチルリチン / 慢性閉塞性呼吸器疾患 / 気道粘液 / ETS転写因子 / 肺サーファクタント / 鎮咳薬 / マスフラグメントグラフィー / 睡眠 / 変異体 / アルブミン / コレステロール代謝 / スルホニルウレア / 痰 / 粘液 / モルモット / パッチクランプ / デキストロメトルファン / グリシン受容体 / スルホニルウレア受容体 / クロライドチャンネル / ニコチニック受容体 / 脳ー内分泌調節系 / 睡眠ー覚醒調節系 / 慢性腎臓病 / アルツハイマー病 / 遺伝子改変マウス / エピジェネティクス / 炎症メモリー / 難病治療薬 / エジプト / 天然資源 / cell specific delivery / Cyclodextrin / Dendrimer / 糖修飾体 / シクロテキストリン / 細胞選択的 / Liver Transplantation / Amyloid / Trace Element / Antibody Treatment / Gene Therapy / Transthvretin / Amyloidosis / 肝移植 / アミロイド / 微量元素 / 抗体治療 / 遺伝子治療 / トランスサイレチン / アミロイドーシス / multifunctionalization / delivery / Lipofectamine 2000 / RNAi効果 / 高機能化 / Tanscription factor / Glucocorticoid / Airway Inflammation / Neutrophil elastase / 粘液遺伝子 / 肺上皮細胞 / MUC1ムチン / aquaporin-5 / Sp3転写因子 / 杯細胞 / レチノイン酸 / Sp1転写因子 / 転写因子 / グルココルチコイド / 気道炎症 / 好中球エラスターゼ / 慢性閉塞性肺疾患 / cytotoxicity / gene transfer / 核移行シグナル / マンノース / ガラクトース / 遺伝子キャリアー / 細胞障害性 / 遺伝子導入 / epithelial cells / lung / pulmonary surfactant / airway mucin / ETS transcription factor / 漢方薬 / ETS-2 / 細胞分化 / 11β-hydroxysteroid dehydrogenase / prostanlandin E_2 / 気道上皮細胞 / 肺 / Clinical application / Blood preparation / Functional evaluation / Artificial blood / Molecular design / Site-directed mutagenesis / Albumin preparation / 人工血液 / 血液製剤 / 臨床応用 / 遺伝子組換え技術 / EPITHELIUM / LUNG / LYSOZYME / 分化 / アポトーシス / リゾチーム / グリシン / 咳 / 麦門冬湯 / lysozyme / elastase / atherosclerosis / cholesterol metabolism / macrophage / glibenclamide / sulfonylureas / 動脈硬化 / patch clamp / single brain neuron / nucleus tractus solitarii / cough center / NMDA receptor / glycine receptor / dextromethorphan / antitussive / 抗けいれん作用 / 中枢単一ニュ-ロン / NーメチルーDーアスパラギン酸(NMDA)リセプタ- / N-メチル-D-アスパラギン酸(NMDA)リセプター / 脳単-ニューロン / 脳単一ニューロン / 孤束核 / 咳中枢 / NMDA受容体 / Cl^-電流 / 下垂体ニューロン / 脳内分泌 / ピペコリン酸 / NANA / シアル酸 / 脳-内分泌 / 癌細胞 / 葉酸レセプター / shRNA / ターゲティング / ターゲッティング / ドラッグデリバリーシステム / ポリエチレングリコール / 葉酸 / 超分子複合体 / ドラッグデリバリー / シグナル伝達 / 生物物理 / 生体分子 / 免疫学 / 蛋白質 / 臓器特異性 / 薬物結合部位 / エスコートプロテイン / 遺伝子工学 / ノックダウンレセプター / MUC5 / MUC2 / ムチン / クリベンクラミド / マイクロダイアリシス / 孤束核ニューロン / コデイン / グリシン誘発電流 / ホモロジー / K-ATPチャネル / 心筋 / 気道分泌 / 睡眠時無呼吸 / セレクテッドイオンモニタリング / ニコチン性Cl^-電流 / コンセントレ-ションクランプ / アプリシア単離ニュ-ロン / 脳幹網様体 / REM睡眠 Less
  • Research Projects

    (50 results)
  • Research Products

    (260 results)
  • Co-Researchers

    (43 People)
  •  Development of novel therapeutic strategies of chronic inflammatory diseases by using inflammatory memory cell visualizing mouse

    • Principal Investigator
      古賀 友紹
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Kumamoto University
  •  Advanced research on the original drug discovery platform for hereditary intractable Alport syndromePrincipal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Kumamoto University
  •  Drug development of incurable diseases with versatile Egyptian natural resources

    • Principal Investigator
      塚本 佐知子
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Kumamoto University
  •  Establishment of research platform for the development of renal precision medicinePrincipal Investigator

    • Principal Investigator
      Kai Hirofumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Kumamoto University
  •  Immunosuppressive effect of novel physical medicine and identification of its receptorPrincipal Investigator

    • Principal Investigator
      Kai Hirofumi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Kumamoto University
  •  慢性腎臓病におけるp53の翻訳後修飾の関与Principal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Drug discovery for Familial amyloid polyneuropathy (FAP), an incurable hereditary diseasePrincipal Investigator

    • Principal Investigator
      KAI HIROFUMI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pharmacology in pharmacy
    • Research Institution
      Kumamoto University
  •  Biological significance of receptors for mild electrical currents at 0.1 ms pulse widthPrincipal Investigator

    • Principal Investigator
      Kai Hirofumi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied pharmacology
    • Research Institution
      Kumamoto University
  •  A new preventive way on diseases using electronic chaperones as a novel conceptPrincipal Investigator

    • Principal Investigator
      KAI Hirofumi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kumamoto University
  •  遺伝性難病FAPの原因タンパク質、トランスサチレインの新たな品質管理機構Principal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Drug development on protein misfolding diseasesPrincipal Investigator

    • Principal Investigator
      KAI Hirofumi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  遺伝性難病FAPの病勢に影響する変異TTRの品質管理機構の解明Principal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Design and evaluation of supramolecular system for siRNA delivery having tumor-cell specific, long-circulating and sustained release properties

    • Principal Investigator
      ARIMA Hidetoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kumamoto University
  •  Therapeutic principles on protein misfolding diseasesPrincipal Investigator

    • Principal Investigator
      KAI Hirofumi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kumamoto University
  •  High functionalization of dendrimer/cyclodextrin conjugate as a novel siRNA carrier

    • Principal Investigator
      ARIMA Hidetoshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kumamoto University
  •  IL-2/Il-2R複合体形成機構の構造生物学的基盤

    • Principal Investigator
      IKEMIZU Shinji
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  New therapeutic approaches for familial amyloidotic polyneuropathy based on the amyloid formation mechanism

    • Principal Investigator
      ANDO Yukio
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kumamoto University
  •  Design and Evaluation of dendrimer/cyclodextrin conjugates as a novel siRNA carrier

    • Principal Investigator
      ARIMA Hidetoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kumamoto University
  •  TLR発現制御におけるCFTR遺伝子変異の影響と分子シャペロンの役割Principal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  変異CFTRの小胞体からの輸送障害機構の解明とエスコート分子の治療への応用Principal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Basic study to develop a new therapeutic drug in chronic obstructive pulmonary disease

    • Principal Investigator
      MIYATA Takeshi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  TLR発現に影響を与える新規因子?CFTR遺伝子変異と分子シャペロン?Principal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  血清アルブミンの新展開:ノックダウンレセプター及びエスコートプロテインとしての可能性

    • Principal Investigator
      OTAGIRI Masaki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kumamoto University
  •  Development of therapeutic ways targeting molecular chaperones and ets transcription factorsPrincipal Investigator

    • Principal Investigator
      KAI Hirofumi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  Design and Evaluation of Dendrimer/Cyclodextrin Conjugate as a Novel Gene Carrier

    • Principal Investigator
      ARIMA Hidetoshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kumamoto University
  •  プロテイントラフィック異常による遺伝性疾患は治療可能か?Principal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kumamoto University
  •  分泌型ムチン自身がマルチマー形成に関わる酵素である可能性について

    • Principal Investigator
      宮田 健
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  Development of therapeutic ways on various pathological features in chronic obstructive pulmonary diseases

    • Principal Investigator
      MIYATA Takeshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kumamoto University
  •  カルネキシンをターゲットにした遺伝性嚢胞性線維症の新規治療法の開発Principal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  新たに見い出した抗糖尿病薬結合タンパク質の同定と動脈硬化抑制薬開発の検討

    • Principal Investigator
      中山 仁
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  MEF plays a role in the pathogenesis of alveolar proteinosis.Principal Investigator

    • Principal Investigator
      KAI Hirofumi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  Design and Evaluation of Albumin Mutants for Clinical Application

    • Principal Investigator
      OTAGIRI Masaki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biological pharmacy
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  カルネキシンスプライシングアイソフォームが新生蛋白質の品質管理機能に及ぼす影響Principal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  気道に分泌されたムチンが酵素としての性質を持ち、自己のマルチマー化を触媒する!?

    • Principal Investigator
      宮田 健
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kumamoto University
  •  新しいスルホニルウレア結合タンパク質の同定およびK-ATPチャネルとの機能協関

    • Principal Investigator
      中山 仁
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  分泌型ムチン自身がマルチマ-形成に関わる酵素である可能性について

    • Principal Investigator
      宮田 健
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  Investigation of Novel Function and Its Relation to Diseases for New Taget Proteins to Which Sulfonylureas Bind

    • Principal Investigator
      NAKAYAMA Hitoshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Kumamoto University
  •  Development of therapeutic ways on various pathological features in chronic obstructive pulmonary diseases

    • Principal Investigator
      MIYATA Takeshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kumamoto University
  •  Novel transcription factor to regulate differentiation of tracheal epithelial cells.Principal Investigator

    • Principal Investigator
      KAI Hirofumi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  新トランスポーター・スルホニルウレア受容体とK-ATPチャネルの構造と機能の解析

    • Principal Investigator
      NAKAYAMA Hitoshi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  卵母細胞翻訳系を用いた脳幹部グリシン受容体の機能と薬理学的意義に関する研究

    • Principal Investigator
      高濱 和夫
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  気道上皮細胞に特異的な遺伝子発現を調節する転写制御因子のクローニングPrincipal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  気道上皮細胞に特異的な遺伝子発現を調節する転写制御因子のクローニングPrincipal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  気道杯細胞特異的遺伝子のクローニングPrincipal Investigator

    • Principal Investigator
      甲斐 広文
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  睡眠ー覚醒調節系及び脳内分泌調節系におけるピペリジンの役割に関する研究

    • Principal Investigator
      宮田 健
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  Studies on neurnoal and ionic mechanisms of the action of antitussives----oriented for development of novel centrally-acting drugs for coming new generarion.

    • Principal Investigator
      TAKAHAMA Kazuo
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kumamoto University
  •  睡眠ー覚醒調節系及び脳ー内分泌調節系におけるピペリジンの役割に関する研究

    • Principal Investigator
      宮田 健
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  睡眠-覚醒調節系および脳-内分泌調節系におけるピペリジンの役割に関する研究

    • Principal Investigator
      MIYATA Takeshi
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  睡眠・覚醒調節系および脳-内分泌調節系におけるピペリジンの役割に関する研究

    • Principal Investigator
      宮田 健
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University
  •  睡眠-覚醒調節系および脳-内分泌調節系におけるピペリジンの役割に関する研究

    • Principal Investigator
      宮田 健
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kumamoto University

All 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Patent

  • [Journal Article] NanoLuc reporters identify COL4A5 nonsense mutations susceptible to drug-induced stop codon readthrough2022

    • Author(s)
      Omachi Kohei、Kai Hirofumi、Roberge Michel、Miner Jeffrey H.
    • Journal Title

      iScience

      Volume: 25 Issue: 3 Pages: 103891-103891

    • DOI

      10.1016/j.isci.2022.103891

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-23K24072
  • [Journal Article] The 2019 and 2021 International Workshops on Alport Syndrome2022

    • Author(s)
      Sergio Daga, Jie Ding, Constantinos Deltas, Judy Savige, Beata S. Lipska-Zietkiewicz, Julia Hoefele, Frances Flinter, Daniel P. Gale, Marina Aksenova, Hirofumi Kai,et al.,
    • Journal Title

      European Journal of Human Genetics

      Volume: 30 Issue: 5 Pages: 507-516

    • DOI

      10.1038/s41431-022-01075-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Journal Article] The role of discoidin domain receptor 2 in the renal dysfunction of alport syndrome mouse model2021

    • Author(s)
      Sannomiya Yuya、Kaseda Shota、Kamura Misato、Yamamoto Hiroshi、Yamada Hiroyuki、Inamoto Masataka、Kuwazuru Jun、Niino Saki、Shuto Tsuyoshi、Suico Mary Ann、Kai Hirofumi
    • Journal Title

      Renal Failure

      Volume: 43 Issue: 1 Pages: 510-519

    • DOI

      10.1080/0886022x.2021.1896548

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07086, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19J23608
  • [Journal Article] Type IV Collagen Variants in CKD: Performance of Computational Predictions for Identifying Pathogenic Variants2021

    • Author(s)
      Shulman Cole、Liang Emerald、Kamura Misato、Udwan Khalil、Yao Tony、Cattran Daniel、Reich Heather、Hladunewich Michelle、Pei York、Savige Judy、Paterson Andrew D.、Suico Mary Ann、Kai Hirofumi、Barua Moumita
    • Journal Title

      Kidney Medicine

      Volume: 3 Issue: 2 Pages: 257-266

    • DOI

      10.1016/j.xkme.2020.12.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Journal Article] Metformin ameliorates the severity of experimental Alport syndrome2021

    • Author(s)
      Omachi Kohei、Kaseda Shota、Yokota Tsubasa、Kamura Misato、Teramoto Keisuke、Kuwazuru Jun、Kojima Haruka、Nohara Hirofumi、Koyama Kosuke、Ohtsuki Sumio、Misumi Shogo、Takeo Toru、Nakagata Naomi、Li Jian-Dong、Shuto Tsuyoshi、Suico Mary Ann、Miner Jeffrey H.、Kai Hirofumi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1

    • DOI

      10.1038/s41598-021-86109-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07086, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19J23608
  • [Journal Article] Activation of heat shock response improves biomarkers of NAFLD in patients with metabolic diseases2021

    • Author(s)
      Kondo Tatsuya、Miyakawa Nobukazu、Kitano Sayaka、Watanabe Takuro、Goto Rieko、Suico Mary Ann、Sato Miki、Takaki Yuki、Sakaguchi Masaji、Igata Motoyuki、Kawashima Junji、Motoshima Hiroyuki、Matsumura Takeshi、Kai Hirofumi、Araki Eiichi
    • Journal Title

      Endocrine Connections

      Volume: 10 Issue: 5 Pages: 521-533

    • DOI

      10.1530/ec-21-0084

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-20K07086, KAKENHI-PROJECT-21K08533
  • [Journal Article] Novel Keap1-Nrf2 Protein-protein interaction inhibitor UBE-1099 Ameliorates Progressive Phenotype in Alport Syndrome mouse model2021

    • Author(s)
      Kaseda Shota、Sannomiya Yuya、Horizono Jun、Kuwazuru Jun、Suico Mary Ann、Ogi Sayaka、Sasaki Ryoko、Sunamoto Hidetoshi、Fukiya Hirohiko、Nishiyama Hayato、Kamura Misato、Niinou Saki、Koyama Yuimi、Nara Futoshi、Shuto Tsuyoshi、Onuma Kazuhiro、Kai Hirofumi
    • Journal Title

      Kidney360

      Volume: - Issue: 4 Pages: 687-699

    • DOI

      10.34067/kid.0004572021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-20K07086
  • [Journal Article] Genetic background, recent advances in molecular biology, and development of novel therapy in Alport syndrome2020

    • Author(s)
      Nozu Kandai、Takaoka Yutaka、Kai Hirofumi、Takasato Minoru、Yabuuchi Kensuke、Yamamura Tomohiko、Horinouchi Tomoko、Sakakibara Nana、Ninchoji Takeshi、Nagano China、Iijima Kazumoto
    • Journal Title

      Kidney Research and Clinical Practice

      Volume: 39 Issue: 4 Pages: 402-413

    • DOI

      10.23876/j.krcp.20.111

    • NAID

      120006956375

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07887, KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-19H03379
  • [Journal Article] Development of an Exon Skipping Therapy for X-linked Alport Syndrome With Truncating Variants in COL4A5.2020

    • Author(s)
      Yamamura T, Horinouchi T, Adachi T, Terakawa M, Takaoka Y, Omachi K, Takasato M, Takaishi K, Shoji T, Onishi Y, Kanazawa Y, Koizumi M, Tomono Y, Sugano S, Shono A, Minamikawa S, Nagano C, Sakakibara N, Ishiko S, Aoto Y, Kamura M, Harita Y, Miura K, Kanda S, Morisada N, and 6 others.
    • Journal Title

      Nat Commun .

      Volume: 11(1) Issue: 1 Pages: 2777-2777

    • DOI

      10.1038/s41467-020-16605-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09921, KAKENHI-PROJECT-18K07887, KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-19K12202, KAKENHI-PROJECT-20K08584, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-18K07414, KAKENHI-PROJECT-18K08243
  • [Journal Article] Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions.2020

    • Author(s)
      K. Oniki, T. Kawakami, A. Nakashima, K. Miyata, T. Watanabe, H. Fujikawa, R. Nakashima, A. Nasu, Y. Eto, N. Takahashi, H. Nohara, M. Ann Suico, S. Kotani, Y. Obata, Y. Sakamoto, Y. Seguchi, J. Saruwatari, T. Imafuku, H. Watanabe, T. Maruyama, H. Kai, T. Shuto
    • Journal Title

      Scientific reports

      Volume: 10 Issue: 1 Pages: 4313-4313

    • DOI

      10.1038/s41598-020-61148-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06997, KAKENHI-PROJECT-19K07166, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-17K08309
  • [Journal Article] Azithromycin Inhibits Constitutive Airway Epithelial Sodium Channel Activation <i>in Vitro</i> and Modulates Downstream Pathogenesis <i>in Vivo</i>2020

    • Author(s)
      Haruka Fujikawa, Taise Kawakami, Ryunosuke Nakashima, Aoi Nasu, Shunsuke Kamei, Hirofumi Nohara, Yuka Eto, Keiko Ueno-Shuto, Toru Takeo, Naomi Nakagata, Mary Ann Suico, Hirofumi Kai, Tsuyoshi Shuto.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 43 Issue: 4 Pages: 725-730

    • DOI

      10.1248/bpb.b19-01091

    • NAID

      130007825345

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2020-04-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07114, KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-17K08309
  • [Journal Article] Trimerization and genotype-phenotype correlation of COL4A5 mutants in Alport syndrome2020

    • Author(s)
      Kamura Misato、Yamamura Tomohiko、Omachi Kohei、Suico Mary Ann、Nozu Kandai、Kaseda Shota、Kuwazuru Jun、Shuto Tsuyoshi、Iijima Kazumoto、Kai Hirofumi
    • Journal Title

      Kidney International Reports

      Volume: - Issue: 5 Pages: 718-726

    • DOI

      10.1016/j.ekir.2020.01.008

    • NAID

      120006818746

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19J15443, KAKENHI-PROJECT-17K08309, KAKENHI-PROJECT-19K08726
  • [Journal Article] Mild electrical stimulation with heat shock attenuates renal pathology in adriamycin-induced nephrotic syndrome mouse model2020

    • Author(s)
      Teramoto Keisuke、Tsurekawa Yu、Suico Mary Ann、Kaseda Shota、Omachi Kohei、Yokota Tsubasa、Kamura Misato、Piruzyan Mariam、Kondo Tatsuya、Shuto Tsuyoshi、Araki Eiichi、Kai Hirofumi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 18719-18719

    • DOI

      10.1038/s41598-020-75761-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19J23608, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-20H01036
  • [Journal Article] Therapeutic strategy to target collagen IV α3α4α5 in Alport syndrome2019

    • Author(s)
      大町 紘平、Suico Mary Ann、首藤 剛、甲斐 広文
    • Journal Title

      生化学

      Volume: 91 Issue: 3 Pages: 413-417

    • DOI

      10.14952/SEIKAGAKU.2019.910413

    • ISSN
      0037-1017
    • Year and Date
      2019-06-25
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-17K08309
  • [Journal Article] A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH2019

    • Author(s)
      Ueda Mitsuharu、Okada Masamitsu、Mizuguchi Mineyuki、et al.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 294 Issue: 29 Pages: 11259-11275

    • DOI

      10.1074/jbc.ra119.007851

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07502, KAKENHI-PROJECT-18K08334, KAKENHI-PROJECT-19K10360, KAKENHI-PROJECT-18K18196, KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19H03565, KAKENHI-PROJECT-18K15455
  • [Journal Article] Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases2019

    • Author(s)
      Nakashima R, Kamei S, Nohara H, Fujikawa H, Maruta K, Kawakami T, Eto Y, Takahashi N, Suico M.A., Takeo T, Nakagawa N, Kai H, Shuto T.
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 140 Issue: 2 Pages: 113-119

    • DOI

      10.1016/j.jphs.2019.01.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-17K08309
  • [Journal Article] Mild electrical stimulation with heat shock guides differentiation of embryonic stem cells into Pdx1-expressing cells within the definitive endoderm.2017

    • Author(s)
      Koga T, Shiraki N, Yano S, Suico MA, Morino-Koga S, Sato T, Shuto T, Kume S, Kai H
    • Journal Title

      BMC Biotechnology

      Volume: 17 Issue: 1 Pages: 14-14

    • DOI

      10.1186/s12896-017-0331-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461638, KAKENHI-PROJECT-15K12514, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-16K01362, KAKENHI-PROJECT-16K18875
  • [Journal Article] 医療機器と薬学2016

    • Author(s)
      甲斐 広文
    • Journal Title

      薬剤学

      Volume: 76 Pages: 92-98

    • NAID

      130005264458

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Journal Article] Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized, open-label, triple-arm trial.2016

    • Author(s)
      Kondo T, Goto R, Ono K, Kitano S, Suico MA, Sato M, Igata M, Kawashima J, Motoshima H, Matsumura T, Kai H, Araki E.
    • Journal Title

      Sci Rep.

      Volume: 19 Issue: 1 Pages: 35690-35690

    • DOI

      10.1038/srep35690

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K12514, KAKENHI-PROJECT-15K09394, KAKENHI-PROJECT-16K09759
  • [Journal Article] TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs.2016

    • Author(s)
      Suzuki S, Sargent RG, Illek B, Fischer H, Esmaeili-Shandiz A, Yezzi MJ, Lee A, Yang Y, Kim S, Renz P, Qi Z, Yu J, Muench MO, Beyer AI, Guimaraes AO, Ye L, Chang J, Fine EJ, Cradick TJ, Bao G, Rahdar M, Porteus MH, Shuto T, Kai H, Kan YW, Gruenert DC
    • Journal Title

      Molecular Therapy Nucleic Acids

      Volume: 5 Pages: e273-e273

    • DOI

      10.1038/mtna.2015.43

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Journal Article] cAMP-dependent protein kinase A acts as a negative regulator for nontypeable Haemophilus influenzae-induced GM-CSF expression via inhibition of MEK-ERK signaling pathway.2016

    • Author(s)
      Tasaki Y, Wang WY, Konduru AS, Komatsu K, Matsuyama S, Kai H, Li JD
    • Journal Title

      Integr Mol Med.

      Volume: 3 Issue: 6 Pages: 1-5

    • DOI

      10.15761/imm.1000261

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Journal Article] Cross-talk between PKA-Cβ and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi.2015

    • Author(s)
      Susuki-Miyata S, Miyata M, Lee BC, Xu H, Kai H, Yan C, Li JD.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 112 Issue: 14

    • DOI

      10.1073/pnas.1418716112

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-15H06771, KAKENHI-PROJECT-25460102
  • [Journal Article] 細胞内ストレスと生活習慣病-分子シャペロンHsp72の耐糖能改善効果とその機序-2015

    • Author(s)
      荒木 栄一, 近藤 龍也, 甲斐 広文
    • Journal Title

      日本体質医学会雑誌

      Volume: 77 Pages: 163-166

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Journal Article] 最適化された微弱パルス電流と温熱の併用療法(physical medicine)の基礎と臨床2015

    • Author(s)
      甲斐 広文, 近藤 龍也, 荒木 栄一
    • Journal Title

      ファルマシア

      Volume: 51 Pages: 1033-1037

    • NAID

      130007447895

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Journal Article] Preemptive quality control protects the ER from protein overload via the proximity of ERAD components and SRP.2015

    • Author(s)
      Kadowaki H, Nagai A, Maruyama T, Takami Y, Satrimafitrah P, Kato H, Honda A, Hatta T, Natsume T, Sato T, Kai H, Ichijo H, Nishitoh H
    • Journal Title

      Cell reports

      Volume: 13 Issue: 5 Pages: 944-956

    • DOI

      10.1016/j.celrep.2015.09.047

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11080, KAKENHI-PUBLICLY-15H01539, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-14J07625, KAKENHI-PROJECT-26860641, KAKENHI-PLANNED-26114009
  • [Journal Article] The effect of mild electrical stimulation with heat shock on diabetic KKAy mice.2015

    • Author(s)
      Kai Y, Tsurekawa Y, Fukuda R, Omachi K, Piruzyan M, Okamoto Y, Motomura K, Suico MA, Shuto T, Kondo T, Araki E, Kai H.
    • Journal Title

      Integr Mol Med.

      Volume: 3 Issue: 1 Pages: 473-477

    • DOI

      10.15761/imm.1000190

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K12514, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-15J09868
  • [Journal Article] Podocyte p53 limits the severity of experimental Alport syndrome.2015

    • Author(s)
      Fukuda R., et al.
    • Journal Title

      Jounal of American Society of Nephrology

      Volume: just accepted Issue: 1 Pages: 144-157

    • DOI

      10.1681/asn.2014111109

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25860223, KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K12514, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-25460102
  • [Journal Article] Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione2015

    • Author(s)
      Yokoyama T, Takaki S, Chosa K, Sato T, Suico MA, Teranishi Y, Shuto T, Mizuguchi M, Kai H
    • Journal Title

      J Pharmacol Sci.

      Volume: 129 Issue: 4 Pages: 240-243

    • DOI

      10.1016/j.jphs.2015.09.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25860022
  • [Journal Article] Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury.2015

    • Author(s)
      Koga T, Suico MA, Shimasaki S, Watanabe E, Kai Y, Koyama K, Omachi K, Morino-Koga S, Sato T, Shuto T, Mori K, Hino S, Nakao M, Kai H.
    • Journal Title

      J Biol Chem.

      Volume: 290 Issue: 51 Pages: 30366-30374

    • DOI

      10.1074/jbc.m115.664169

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25430178, KAKENHI-PROJECT-25460102
  • [Journal Article] Mild Electrical Stimulation Increases Stress Resistance and Suppresses Fat Accumulation via Activation of LKB1-AMPK Signaling Pathway in C. elegans2014

    • Author(s)
      Shingo Matsuyama, Masataka Moriuchi, Mary Ann Suico, Shuichiro Yano, Saori Morino-Koga, Tsuyoshi Shuto, Kunitoshi Yamanaka, Tatsuya Kondo, Eiichi Araki, Hirofumi Kai
    • Journal Title

      PLOS ONE

      Volume: 9(12): e114690 Issue: 12 Pages: e114690-e114690

    • DOI

      10.1371/journal.pone.0114690

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J10549, KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25670260, KAKENHI-PROJECT-26460098
  • [Journal Article] The transcription factor MEF/ELF4 is dually modulated by p53-MDM2 axis and MEF-MDM2 autoregulatory mechanism.2014

    • Author(s)
      Suico MA, Fukuda R, Miyakita R, Koyama K, Taura M, Shuto T, Kai H.
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 289(38) Issue: 38 Pages: 26143-54

    • DOI

      10.1074/jbc.m114.580209

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J08328, KAKENHI-PUBLICLY-25117721, KAKENHI-PROJECT-26460098
  • [Journal Article] Mild electrical stimulation with heat shock reduces visceral adiposity and improves metabolic abnormalities in subjects with metabolic syndrome or type 2 diabetes: Randomized crossover trials.2014

    • Author(s)
      Kondo T, Ono K, Kitano S, Matsuyama R, Goto R, Suico MA, Kawasaki S, Igata M, Kawashima J, Motoshima H, Matsumura T, Kai H, Araki E
    • Journal Title

      EBioMedicine

      Volume: 1 Issue: 1 Pages: 80-89

    • DOI

      10.1016/j.ebiom.2014.11.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461360, KAKENHI-PROJECT-25461374, KAKENHI-PROJECT-25670260, KAKENHI-PROJECT-26460098
  • [Journal Article] The role of heat shock response in insulin resistance and diabetes.2014

    • Author(s)
      Kondo T, Motoshima H, Igata M, Kawashima J, Matsumura T, Kai H, Araki E
    • Journal Title

      Diabetes Metab J

      Volume: 38 Issue: 2 Pages: 100-1006

    • DOI

      10.4093/dmj.2014.38.2.100

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461360, KAKENHI-PROJECT-25461374, KAKENHI-PROJECT-25670260, KAKENHI-PROJECT-26460098
  • [Journal Article] Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.2014

    • Author(s)
      Suzuki S, Shuto T, Sato T, Kaneko M, Takada T, Suico MA, Cyr DM, Suzuki H, Kai H
    • Journal Title

      Scientific reports

      Volume: 4 Issue: 1 Pages: 4258-4258

    • DOI

      10.1038/srep04258

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23790095, KAKENHI-PROJECT-24300135, KAKENHI-PROJECT-24659068, KAKENHI-PROJECT-24790079, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25460102, KAKENHI-PROJECT-26460099
  • [Journal Article] Mild electrical stimulation at 0.1-ms pulse width induces p53 protein phosphorylation and G2 arrest in human epithelial cells.2013

    • Author(s)
      Fukuda ft, Suico MA, Koyama K, Omachi K, Kai Y, Matsuyama S, Mitsutake K, Taura M, Mo rino-Koga S, Shuto T, Kai H.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 288(22) Issue: 22 Pages: 16117-16126

    • DOI

      10.1074/jbc.m112.442442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08328, KAKENHI-PROJECT-13J08535, KAKENHI-PROJECT-23590082, KAKENHI-PUBLICLY-25117721, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25460102, KAKENHI-PROJECT-25670260
  • [Journal Article] Evaluation of Three-Dimensional Cultured HepG2 Cells in a Nano Culture Plate System: an In Vitro Human Model of Acetaminophen Hepatotoxicity.2013

    • Author(s)
      Kohei Aritomi, Yoichi Ishitsuka, Yoshiro Tomishima, Daisuke Shimizu, Nazuki Abe, Tsuyoshi Shuto, Mitsuru Irikura, Hirofumi Kai, and Tetsumi Irie.
    • Journal Title

      J Pharmacpl Sci.

      Volume: 124 Pages: 218-229

    • NAID

      130003391476

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Journal Article] Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD2013

    • Author(s)
      Komatsu K
    • Journal Title

      Nature Communications

      Volume: 4 Issue: 1 Pages: 1684-1684

    • DOI

      10.1038/ncomms2674

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790091, KAKENHI-PROJECT-23890146, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25860223
  • [Journal Article] Mild electrical stimulation with heat stimulation increase heat shock protein 70 in articular chondrocyte.2013

    • Author(s)
      Hiraoka N,Arai Y, Takahashi KA, Mazda O, Kishida T, Honjo K, Tsuchida S, Inoue H, Morino S, Suico MA, Kai H, Kubo T.
    • Journal Title

      J Orthop Res.

      Volume: 17 Issue: 6 Pages: 894-900

    • DOI

      10.1002/jor.22307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591318, KAKENHI-PROJECT-23650333, KAKENHI-PROJECT-24659447, KAKENHI-PROJECT-25670260, KAKENHI-PROJECT-25670656
  • [Journal Article] Diethyldithiocarbamate induces apoptosis in HHV-8-infected primary effusion lymphoma cells via inhibition of the NF-κB pathway2012

    • Author(s)
      Matsuno T, Kariya R, Yano S, Morino-Koga S, Taura M, Suico MA, Shimauchi y Matsuyama S, Okamoto Y, Shuto T, Kai H, Okada S
    • Journal Title

      Int J Oncol

      Volume: 40(4) Pages: 1071-1078

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] SynergismBetween Interleukin (IL)-17 and Toll-likeReceptor 2 and 4 Signals to Induce IL-8Expression in Cystic Fibrosis AirwayEpithelial Cells2012

    • Author(s)
      Mizunoe S, Shuto T, Suzuki S, MatsumotoC, Watanabe K, Ueno-Shuto K, Suico MA,Onuki K, Gruenert DC, Kai H
    • Journal Title

      J. Pharmacol. Sci

      Volume: 118 Pages: 512-520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Rb/E2F1 Regulates the Innate Immune Receptor Toll-Like Receptor 3 in Epithelial Cells2012

    • Author(s)
      Taura M, Suico MA, Koyama K, Komatsu K, Miyakita R, Matsumoto C, Kudo E, Kdriya R, Goto H, Kitajima S, Takahashi C, Shuto T, Nakao M, Okada S, Kai H
    • Journal Title

      Mol Cell Biol

      Volume: 32(8) Pages: 1581-1590

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Journal Article] Diethyldithiocarbamate induces apoptosis in HHV-8-infected primary effusion lymphoma cells via inhibition of the NF-κB pathway2012

    • Author(s)
      Matsuno T, Kariya R, Yano S, Morino-Koga S, Taura M, Suico MA, Shimauchi Y, Matsuyama S, Okamoto Y, Shuto T, Kai H, Okada S
    • Journal Title

      Int J Oncol

      Volume: 40(4) Pages: 1071-1078

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Journal Article] Insulinreceptor activation through itsaccumulation in lipid rafts by mildelectrical stress.2012

    • Author(s)
      Morino-Koga S, Yano S, Kondo T,Shimauchi Y, Matsuyama S, Okamoto Y,Suico MA, Koga T, Sata T, Shuto T, ArimaH, Wada I, Araki E, Kai H.
    • Journal Title

      J. Cell. Physiol

      Volume: 228 Pages: 439-446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Journal Article] Hyperthermia With MildElectrical Stimulation ProtectsPancreatic β -Cells From CellStresses and Apoptosis.2012

    • Author(s)
      Kondo T, Sasaki K, Matsuyama R,Morino-Koga S, Adachi H, Suico MA,Kawashima J, Motoshima H, Furukawa N,Kai H, Araki E.
    • Journal Title

      Diabetes

      Volume: 61 Pages: 838-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Journal Article] Rb/E2F1 Regulates the Innate Immune Receptor Toll-Like Receptor 3 in Epithelial Cells2012

    • Author(s)
      Taura M, Suico MA, Koyama K, Komatsu K, Miyakita R, Matsumoto C, Kudo E, Kariya R, Goto H, Kitajima S, Takahashi C, Shuto T, Nakao M, Okada s, Kai H
    • Journal Title

      Mol Cell Biol

      Volume: 32(8) Pages: 1581-1590

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells2012

    • Author(s)
      Mizunoe S, Shuto T, Suzuki S, Matsumoto C, Watanabe K, Ueno-Shuto K, Suico MA, Onuki K, Gruenert DC, Kai H
    • Journal Title

      J Pharmacol Sci

      Volume: (印刷中)

    • NAID

      10030572169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Mild electrical stimulation andheat shock ameliorates progressiveproteinuria and renal inflammation inmouse model of alport syndrome2012

    • Author(s)
      Koga T, Kai Y, Fukuda R, Morino-Koga S,Suico MA, Koyama K, Sato T, Shuto T, KaiH.
    • Journal Title

      PLoSOne

      Volume: 7(8)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Journal Article] STT3B-dependent posttranslationalN-glycosylation as a novel surveillancesystem for secretory protein2012

    • Author(s)
      Sato T, Sako Y, Sho M, Momohara M, SuicoMA, Shuto T, Nishitoh H, Okiyoneda T,Kokame K, Kaneko M, Taura M, Miyata M,Chosa K, Koga T, Koga SM, Wada I, Kai H
    • Journal Title

      Mol. Cell

      Volume: 47 Pages: 99-110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis2012

    • Author(s)
      Kondo T, Sasaki K, Matsuyama R, Morino-Koga S, Adachi H, Suico MA, Kawashima J, Motoshima H, Furukawa N, Kai H, Araki E
    • Journal Title

      Diabetes

      Volume: 61(4) Pages: 838-847

    • NAID

      120005368280

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Journal Article] Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells2012

    • Author(s)
      Mizunoe S, Shuto T, Suzuki S, Matsumoto C, Watanabe K, Ueno-Shuto K, Suico MA, Onuki K, Gruenert DC, Kai H
    • Journal Title

      J Pharmacol Sci

      Volume: (印刷中)

    • NAID

      10030572169

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Journal Article] Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis.2012

    • Author(s)
      Kondo T, Sasaki K, Matsuyama R, Morino-Koga S, Adachi H, Suico MA, Kawashima J, Motoshima H, Furukawa N, Kai H, Araki E.
    • Journal Title

      Diabetes.

      Volume: 61(4) Pages: 838-847

    • NAID

      120005368280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Journal Article] Rb/E2F1 Regulatesthe Innate Immune Receptor Toll-LikeReceptor 3 in Epithelial Cells2012

    • Author(s)
      Taura M, Suico MA, Koyama K, Komatsu K,Miyakita R, Matsumoto C, Kudo E, Kariya R,Goto H, Kitajima S, Takahashi C, Shuto T,Nakao M, Okada S, Kai H
    • Journal Title

      Mol. Cell.Biol

      Volume: 32 Pages: 1581-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis2012

    • Author(s)
      Kondo T, Sasaki K, Matsuyama R, Morino-Koga S, Adachi H, Suico MA, Kawashima J, Motoshima H, Furukawa N, Kai H, Araki E
    • Journal Title

      Diabetes

      Volume: 61(4) Pages: 838-847

    • NAID

      120005368280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] CFTR-deficiency renders mice highly susceptible to cutaneous symptoms during mite infestation2011

    • Author(s)
      Hashimoto Y, Shuto T, Mizunoe S, Tomita A, Koga T, Sato T, Takeya M, Suico MA, Niibori A, Sugahara T, Shimasaki S, Sugiyama T, Scholte B, Kai H
    • Journal Title

      Lab Invest

      Volume: 91(4) Pages: 509-518

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Journal Article] Lucidenic acids-rich extract from antlered form of Ganoderma lucidum enhances TNF α induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK2011

    • Author(s)
      Watanabe K, Shuto T, Sato M, Onuki K, Mizunoe S, Suzuki S, Sato T, Koga T, Suico MA, Kai H, Ikeda T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 408(1) Pages: 18-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] CFTR-deficiency renders mice highlysusceptible to cutaneous symptoms duringmite infestation2011

    • Author(s)
      Hashimoto Y, Shuto T, Mizunoe S, TomitaA, Koga T, Sato T, Takeya M, Suico MA,Niibori A, Sugahara T, Shimasaki S,Sugiyama T, Scholte B, Kai H
    • Journal Title

      Lab Invest

      Volume: 91(4) Pages: 509-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Lucidenic acids-rich extract from antlered form of Ganoderma lucidum enhances TNFα induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK2011

    • Author(s)
      Watanabe K, Shuto T, Sato M, Onuki K, Mizunoe S, Suzuki S, Sato T, Koga T, Suico MA, Kai H, Ikeda T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 408(1) Pages: 18-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Journal Article] Posttranslational negative regulation of glycosylated and non-glycosylated BCRP expression by Derlin-12011

    • Author(s)
      Sugiyama T, Shuto T, Suzuki S, Sato T, Koga T, Suico MA, Kusuhara H, Sugiyama Y, Cyr DM, Kai H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 404(3) Pages: 853-858

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] CFTR-deficiency renders mice highly susceptible to cutaneous symptoms during mite infestation2011

    • Author(s)
      Hashimoto Y, Shuto T, Mizunoe S, Tomita A, Koga T, Sato T, Takeya M, Suico MA, Niibori A, Sugahara T, Shimasaki S, Sugiyama T, Scholte B, Kai H
    • Journal Title

      Lab Invest

      Volume: 91(4) Pages: 509-518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Posttranslational negative regulation of glycosylated and non-glycosylated BCRP expression by Derlin-12011

    • Author(s)
      Sugiyama T, Shuto T, Suzuki S, Sato T, Koga T, Suico MA, Kusuhara H, Sugiyama Y, Cyr DM, Kai H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 404(3) Pages: 853-858

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Journal Article] Glucose Uptake in Rat Skeletal Muscle L6 Cells Is Increased by Low-Intensity Electrical Current Through the Activation of the Phosphatidylinositol-3-OH kinase (PI-3K) / Akt Pathway.2011

    • Author(s)
      Yano S, Morino-Koga S, Kondo T, Suico MA, Koga T, Shimauchi Y, Matsuyama S, Shuto T, Sato T, Araki E, Kai H.
    • Journal Title

      J Pharmacol Sci.

      Volume: 115(1) Pages: 94-98

    • NAID

      10029891696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Journal Article] Heat shockresponse regulates insulinsensitivity and glucose homeostasis:pathophysiological impact andtherapeutic potential.2011

    • Author(s)
      Kondo T, Koga S, Matsuyama R, MiyagawaK, Goto R, Kai H, Araki E.
    • Journal Title

      urr. DiabetesRev

      Volume: 7(4) Pages: 264-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Journal Article] GlucoseUptake in Rat Skeletal Muscle L6 CellsIs Increased by Low-IntensityElectrical Current Through theActivation of thePhosphatidylinositol-3-OH kinase(PI-3K) / Akt Pathway.2011

    • Author(s)
      Yano S, Morino-Koga S, Kondo T, SuicoMA, Koga T, Shimauchi Y, Matsuyama S,Shuto T, Sato T, Araki E, Kai H.
    • Journal Title

      J Pharmacol Sci

      Volume: 115(1) Pages: 94-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Journal Article] Posttranslational negativeregulation of glycosylated andnon-glycosylated BCRP expression byDerlin-12011

    • Author(s)
      Sugiyama T, Shuto T, Suzuki S, Sato T,Koga T, Suico MA, Kusuhara H, Sugiyama Y,Cyr DM, Kai H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 404(3) Pages: 853-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] MEF/ELF4 transactivation by E2F1 isinhibited by p532011

    • Author(s)
      Taura M, Suico MA, Fukuda R, Koga T,Shuto T, Sato T, Morino-Koga S, Okada S, KaiH
    • Journal Title

      Nucleic Acids Res

      Volume: 39(1) Pages: 76-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Curcumindecreases toll-like receptor-2 geneexpression and function in human monocytesand neutrophils2010

    • Author(s)
      Shuto T, Ono T, Ohira Y, Shimasaki S,Mizunoe S, Watanabe K, Suico MA, Koga T,Sato T, Morino S, Sato K, Kai H
    • Journal Title

      Biochem Biophys ResCommun

      Volume: 398(4) Pages: 647-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding2010

    • Author(s)
      Miyata M, Sato T, Mizuguchi M, Nakamura T, Ikemizu S, Nabeshima Y, Susuki S, Suwa Y, Morioka H, Ando Y, Suico MA, Shuto T, Koga T, Yamagata Y, Kai H
    • Journal Title

      Biochemistry 49

      Pages: 114-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] TLR3 induction by anticancer drugspotentiates poly I:C-induced tumor cellapoptosis2010

    • Author(s)
      Taura M, Fukuda R, Suico MA, Eguma A,Koga T, Shuto T, Sato T, Morino-Koga S, KaiH
    • Journal Title

      Cancer Sci

      Volume: 101(7) Pages: 1610-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Role of theglutamic acid 54 residue in transthyretin stability and thyroxine binding2010

    • Author(s)
      Miyata M, Sato T, Mizuguchi M, NakamuraT, Ikemizu S, Nabeshima Y, Susuki S, SuwaY, Morioka H, Ando Y, Suico MA, Shuto T,Koga T, Yamagata Y, and Kai H
    • Journal Title

      Biochemistry

      Volume: 49 Pages: 114-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] TLR3 induction by anticancer drugs potentiates poly I:C-induced tumor cell apoptosis2010

    • Author(s)
      Manabu Taura, R. Fukuda, Mary Ann Suico, Ayaka Eguma, Tomoaki Koga, Tsuyoshi Shuto, Takashi Sato, Saori Koga Morino, Hirofumi Kai
    • Journal Title

      Cancer Sci (in press)

    • NAID

      10026594490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Crystal structure of green teapolyphenol(-)-epigallocatechin gallate(EGCG)-transthyretin complex revealsnovel binding site distinct fromthyroxine binding site2010

    • Author(s)
      Miyata M, Sato T, Kugimiya M, Sho M,Nakamura T, Ikemizu S, Chirifu M,Mizuguchi M, Nabeshima Y, Suwa Y, MoriokaH, Arimori T, Suico MA, Shuto T, Sako Y,Momohara M, Koga T, Morino-Koga S, YamagataY, Kai H
    • Journal Title

      Biochemistry

      Volume: 49 Pages: 6104-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Heat shock treatment with mild electrical stimulation safely reduced inflammatory markers in healthy male subjects2010

    • Author(s)
      Kondo, T., Sasaki, K., Adachi, H., Nakayama, Y., Hatemura, M., Matsuyama, R., Tsuruzoe, K., Furukawa, N., Motoshima, H., Morino, S., Yamashita Y., Miyamura N., Kai H., Araki E
    • Journal Title

      Obesity Research, Clinical Practice 4

    • NAID

      120003184552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Endoplasmicreticulum stress increases the expressionand function of toll-like receptor-2 inepithelial cells2010

    • Author(s)
      Shimasaki S, Koga T, Shuto T, Suico MA,Sato T, Watanabe K, Morino-Koga S, TauraM, Okada S, Mori K and Kai H
    • Journal Title

      Biochem Biophys ResCommun

      Volume: 402(2) Pages: 235-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Journal Article] Modified Mild Heat Shock Modality Attenuates Hepatic Ischemia/Reperfusion Injury2010

    • Author(s)
      Mariko Oba, Mary Ann Suico, Saori Morino, Shuichiro Yano, Takashi Matsuno, Tomoaki Koga, Takashi Sato, Tsuyoshi Shuto, Hirofumi Kai
    • Journal Title

      J. Surg. Res (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] A novel combination of mild electrical stimulation and hyperthermia : general concepts and applications.2009

    • Author(s)
      Kai H, et al.
    • Journal Title

      Int J Hyperthermia. 25(8)

      Pages: 655-660

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20059027
  • [Journal Article] Calreticulin positively regulates the expression and function of epithelial sodium channel2009

    • Author(s)
      Takuya Sugahara, Tomoaki Koga, Keiko Ueno-Shuto, Tsuyoshi Shuto, Eriko Watanabe, Maekawa A., Kitamura K., Tomita K., Ai Mizuno, Takashi Sato, Mary Ann Suico, Hirofumi Kai
    • Journal Title

      Exp. Cell Res 315

      Pages: 3294-300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP in mammalian cells2009

    • Author(s)
      Susuki S, Sato T, Miyata M, Momohara M, Suico MA, Shuto T, Ando Y, Kai H
    • Journal Title

      J Biol Chem 284

      Pages: 8312-8321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] A novel combination of mild electrical stimulation and hyperthermia : general concepts and applications2009

    • Author(s)
      Kai H, et al.
    • Journal Title

      Int J Hyperthermia 25(8)

      Pages: 655-660

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] The expression of antimicrobial peptide lysozyme is increased by treatment with silver nanoparticle (Atomyball SR) in mammalian epithelial cells2009

    • Author(s)
      Mary Ann Suico, Atsushi Tanaka, Tsuyoshi Shuto, Hirofumi Kai
    • Journal Title

      J. Health Sci 55

      Pages: 456-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] A novel combination of mild electrical stimulation and hyperthermia: general concepts and applications (review)2009

    • Author(s)
      Hirofumi Kai, Mary Ann Suico, Saori Morino, Tatsuya Kondo, Mariko Oba, Mikiko Noguchi, Tsuyoshi Shuto, Eiichi Araki
    • Journal Title

      Int. J. Hyperthermia 25

      Pages: 655-660

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Mild Electrical Stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling. Increases Ubiquitinated Proteins and Hsp72 in A549 Cells via Attenuation of Proteasomal Degradation2008

    • Author(s)
      Saori Morino, Tatsuya Kondo, Kazunari Sasaki, Hironori Adachi, Mary Ann Suico, Erika Sekimoto, Tomoko Matsuda, Tsuyoshi Shuto, Eiichi Araki, Hirofumi Kai
    • Journal Title

      PLoS ONE 3(12)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Interferon-gamma down-regulated Hsp27 and enhances hyperthermia-induced tumor cell death in vitro and tumor suppression in vivo2008

    • Author(s)
      Oba M., Yano S., Shuto T., Suico M.A., Eguma A., Kai H
    • Journal Title

      Int. J. Oncol 32

      Pages: 1317-1324

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] p53 regulates TLR3 expression and function in human epithelial cell lines2008

    • Author(s)
      Manabu Taura, Ayaka Eguma, Mary Ann Suico, Tsuyoshi Shuto, Tomoaki Koga, Kensei Komatsu, Takefumi Komune, Takashi Sato, Hideyuki Saya, Jian-Dong Li, Hirofumi Kai
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 6557-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Mild Electrical Stimulation Increases Ubiquitinated Proteins and Hsp72 in A549 Cells via Attenuation of Proteasomal Degredation2008

    • Author(s)
      Saori Morino, Mary Ann Suico, Tatsuya Kondo, Erika Sekimoto, Shuichiro Yano. Tomoko Matsuda, Takashi Matsuno, Tsuyoshi Shuto, Eiichi Araki, Hirohumi Kai
    • Journal Title

      J Pharmacol Sci 108

      Pages: 222-226

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Phosphatidic acid metabolism regulate the intracellular trafficking and retrotranslocation of cystic fibrosis transmembrane conductance regulator. Biochem2008

    • Author(s)
      Yasuaki Hashimoto, Tsukasa Okiyoneda, Kazutsune Harada, Keiko Ueno, Takuya Sugahara, Atsushi Yamashita, Tsuyoshi Shuto, Mary Ann Suico, Hirofumi Kai
    • Journal Title

      Biochim. Acta (Mol. Cell Res. ) 1783

      Pages: 153-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and DF508 CFTR2008

    • Author(s)
      Okiyoneda T., Niibori A., Harada K., Kohno T., Michalak M., Duszyk M., Wada I., Ikawa M., Shuto T., Suico M. A, Kai H
    • Journal Title

      Biochem. Biochim. Acta (Mol. Cell Res. ) 1783

      Pages: 1585-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription2008

    • Author(s)
      Takashi Furuta, Tsuyoshi Shuto, Shogo Shimasaki, Yuko Ohira, Mary Ann Suico, Dieter C Gruenert, Hirofumi Kai
    • Journal Title

      BMC Mol Biol 9

      Pages: 39-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Multi-elemental analysis of serum and amyloid fibrils in familial amyloid polyneuropathy patients2008

    • Author(s)
      Susuki S., Ando Y., Sato T., Nishiyama M., Miyata M., Suico MA., Shuto T., Kai H
    • Journal Title

      Amyloid (The Journal of Protein Folding Disorders) 15

      Pages: 108-116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Curucumin enhances cystic fibrosis transmembrane regulator expression by down-regulating calreticulin, Biochem2007

    • Author(s)
      Kazutsune Harada, Tsukasa Okiyoneda, Yasuaki Hashimoto, Kimiko Oyokawa, Kimitoshi Nakamura, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai
    • Journal Title

      Biophys. Res. Commun 353

      Pages: 351-356

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Increased responsiveness to TLR2 and TLR4 ligands during dimethylsulfoxideinduced neutrophil-like differentiation of HL-60 myeloid leukemia cells2007

    • Author(s)
      Tsuyoshi Shuto, Takashi Furuta, Judy Cheung, Dieter C. Gruenert, Yuko Ohira, Shogo Shimasaki, Mary Ann Suico, Keizo Sato, Hirofumi Kai
    • Journal Title

      Leuk Res 31

      Pages: 1721-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Journal Article] Chromium (III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation.2006

    • Author(s)
      Sato, T., Ando, Y., Susuki, S., Mikami, F., Ikemizu, S., Nakamura, M., Suhr, O., Anraku, M., Kai, T., Suico.M.A., Shuto, T., Mizuguchi, M., Yamagata, Y., Kai H.
    • Journal Title

      FEBS Letters 580

      Pages: 491-496

    • NAID

      120005499991

    • Data Source
      KAKENHI-PROJECT-17053022
  • [Journal Article] Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression2005

    • Author(s)
      T.Roger, I.Miconnet, A.-L.Schiesser, H.Kai, K.Miyake, T.Calandra
    • Journal Title

      Biochem.J. 387

      Pages: 355-365

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Sp1 is involved in the transcriptional activation of lysozyme in epithelial cells2004

    • Author(s)
      Mary Ann Suico, Tomoaki Koga, Tsuyoshi Shuto, Akinori Hisatsune, Zhuo Lu, Carol Basbaum, Tsukasa Okiyoneda, Hirofumi Kai
    • Journal Title

      Biochem.Biophys.Res.Chem. 324

      Pages: 1302-1308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] The ETS transcription factor MEF up-regulates lysozyme transcription in Epithelial cells through interaction with PML protein2004

    • Author(s)
      Mary Ann Suico, Hiroki Yoshida, Yoshiyuki Seki, Tomoko Uchikawa, Zhuo Lu, Tsuyoshi Shuto, Kazuhito Matsuzaki, Mitsuyoshi Nakao, Jian-Dong Li, Hirofumi Kai
    • Journal Title

      J.Biol.Chem. 279

      Pages: 19091-19098

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] DeltaF508 CFTR pool in the ER is increased by calnexin overexpression2004

    • Author(s)
      Tsukasa Okiyoneda, Kazutsune Harada, Motohiro Takeya, Kaori Yamahira, Ikuo Wada, Tsuyoshi Shuto, Mary Ann Suico, Yasuaki Hashimoto, Hirofumi Kai
    • Journal Title

      Mol.Biol.Cell 15

      Pages: 563-574

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Characterization of the trafficking pathway of cystic fibrosis transmembrane conductance regulator in baby hamster kidney cells.2004

    • Author(s)
      T.Okiyoneda, K.Harada, K.Yamahira, I.Wada, Y.Hashimoto, K.Ueno, M.A.Suico, T.Shuto, H.Kai
    • Journal Title

      J.Pharmacol.Sci. 95

      Pages: 471-475

    • NAID

      10014165976

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] MEF up-regulates human beta-defensin 2 expression in epithelial cells2004

    • Author(s)
      Zhuo Lu, Kyoung-Ah Kim, Mary Ann Suico, Tsuyoshi Shuto, Jian-Dong Li, Hirofumi Kai
    • Journal Title

      FEBS Letters 561

      Pages: 117-121

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] The regulation of human _-defensin 2 by the ETS transcription factor MEF is enhanced by PML protein2004

    • Author(s)
      M.Suico, Z.Lu, T.Shuto, T.Koga, T.Uchikawa, H.Yoshida, K.Matsuzaki, M.Nakao, J.-D.Li, H.Kai
    • Journal Title

      J.Pharmacol.Sci. 95

      Pages: 466-470

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] ETS2 is involved in protein kinase C-activated expression of granulocyte-macrophage colony-stimulating factor in human non-small lung carcinoma cell line, A549.2003

    • Author(s)
      Lu Z, Kim KA, Suico MA, Uto A, Seki Y, Shuto T, Isohama Y, Miyata T, Kai H
    • Journal Title

      Biochem Biophys Res Commun 303

      Pages: 190-195

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390030
  • [Journal Article] ETS2 is involved in protein kinase C-activated expression of granulocyte-macrophage colony-stimulating factor in human non-small lung carcinoma cell line, A549.2003

    • Author(s)
      Z.Lu, K.Kim, M.Suico, A.Uto, Y.Seki, T.Shuto, Y.Isohama, T.Miyata, H.Kai
    • Journal Title

      Biochem.Biophys.Res.Commun. 303

      Pages: 190-195

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] TGF-b-Smad signaling pathway negatively regulates nontypeable haemophilus influenzae-induced MUC5AC Mucin transcription via MARK phosphatase-1-dependent inhibition of P38 MARK.2003

    • Author(s)
      H.Jono, H.Xu, H.Kai, D.J Lim, Y.S Kim, X.-H.Feng, J.-D.Li
    • Journal Title

      J.Biol.Chem. 278

      Pages: 27811-27819

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Steryl Glucoside is a lipid mediator in stress-responsive signal transduction.2002

    • Author(s)
      S.Kunimoto, W.Murofushi, H.Kai, Y.Ishida, A.Uchiyama, T.Kobayashi, S.Kobayashi, H.Murofushi, K.Murofushi-Murakami
    • Journal Title

      Cell Structure Function 27

      Pages: 157-162

    • NAID

      50000617080

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Introduction of the conventional method of DNA transfection by adenovirus vector.2002

    • Author(s)
      Okiyoneda T, Kai H
    • Journal Title

      Nippon Yakurigaku Zasshi (Japanese) 119(6)

      Pages: 337-344

    • NAID

      10008992266

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Amyloid formation in rat transthyretin : effect of oxidative stress.2002

    • Author(s)
      Tajiri T, Ando Y, Hata K, Kamiide K, Hashimoto M, Nakamura M, Terazaki H, Yamashita T, Kai H, Haraoka K, Imasato A, Takechi K, Nakagawa K, Ishizaki T
    • Journal Title

      Clin Chim Acta. 323(1-2)

      Pages: 129-137

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] TGF-b-Smad signaling pathway cooperates with NF-kB to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription2002

    • Author(s)
      H.Jono, T.Shuto, H.Xu, H.Kai, D.J Lim, J.R Gum, Y.S Kim, S.Yamaoka, X.-H.Feng, J.-D.Li
    • Journal Title

      J.Bioi.Chem. 277

      Pages: 45547-45557

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Functional dissection of the ETS transcription factor MEF2002

    • Author(s)
      M.-A.Suico, T.Koyanagi, S.Ise, Z.Lu, A.Hisatsune, Y.Seki, T.Shuto, Y.Isohama, T.Miyata, H.Kai
    • Journal Title

      Biochem.Biochim.Acta 1577

      Pages: 113-120

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Calnexin Δ185-520 partially reverses the misprocessing of the ΔF508 cystic fibrosis transmembrane conductance regulator.2002

    • Author(s)
      T.Okiyoneda, I.Wada, H.Jono, T.Shuto, K.Yoshitake, N.Nakano, S.Nagayama, K.Harada, Y.Isohama, T.Miyata, H.Kai
    • Journal Title

      FEBS letters 526

      Pages: 87-92

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] A novel localized amyloidosis associated with lactoferrin in the cornea.2002

    • Author(s)
      Y.Ando, M.Nakamura, H.Kai, S.Katsuragi, H.Terazaki, T.Nozawa, T.Okuda, S.Misumi, N.Matsunaga, K.Hata, T.Tajiri, S.Shoji, T.Yamashita, K.Haraoka, K.Obayashi, K.Matsumoto, M.Ando, M.Uchino
    • Journal Title

      Lab.Invest. 82

      Pages: 757-766

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase.2002

    • Author(s)
      Shuto T, Imasato A, Jono H, Sakai A, Xu H, Watanabe T, Rixter DR, Kai H, Andalibi A, Linthicum F, Guan YL, Han J, Cato AC, Lim DJ, Akira S, Li JD.
    • Journal Title

      J Biol Chem. 277(19)

      Pages: 17263-17270

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Inhibition of p38 MARK by Glucocorticoids via induction of MARK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of Toll-like receptor 2.2002

    • Author(s)
      A.Imasato, C.Desbois-Mouthon, J.Han, H.Kai, A.C.B.Cato, S.Akira, J.-D.Li
    • Journal Title

      J.Biol.Chem. 277

      Pages: 47444-47450

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] The ETS transcription factor MEF is a candidate tumor suppressor gene on the X chromosome2002

    • Author(s)
      Y.Seki, M.-A.Suico, A.Uto, A.Hisatsune, T.Shuto, Y.Isohama, H.Kai
    • Journal Title

      Cancer Res 62

      Pages: 6579-6586

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370748
  • [Journal Article] Endoplasmic reticulum quality control regulates the fate of transthyretin variants in the cell

    • Author(s)
      Takashi Sato, Seiko Susuki, Mary Ann Suico, Masanori Miyata, Yukio Ando, Mineyuki Mizuguchi, Makoto Takeuchi, Mizuki Dobashi, Tsuyoshi Shuto, Hirofumi Kai
    • Journal Title

      EMBO J 26

      Pages: 2501-2512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Patent] 難治性遺伝性腎疾患アルポート症候群の根治療法のための薬剤2020

    • Inventor(s)
      甲斐,首藤,メリーアン,塚本,三隅,河原,人羅,加藤,小谷,荒木
    • Industrial Property Rights Holder
      甲斐,首藤,メリーアン,塚本,三隅,河原,人羅,加藤,小谷,荒木
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Patent] 難治性遺伝性腎疾患アルポート症候群の根治療法のための薬剤2019

    • Inventor(s)
      甲斐広文ら,他7名
    • Industrial Property Rights Holder
      甲斐広文ら,他7名
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Patent] アミロイドーシスの予防及び治療のための医療2002

    • Inventor(s)
      甲斐広文, 安東由喜男
    • Industrial Property Rights Holder
      甲斐広文, 安東由喜男
    • Filing Date
      2002-05-14
    • Data Source
      KAKENHI-PROJECT-17390254
  • [Presentation] AKI to CKD transitionモデルマウスに対する微弱パルス電流と温熱の同時印加の効果2022

    • Author(s)
      津波古 遥希、寺本 啓祐、加世田 将大、Piruzyan Mariam、岩上 長巨、荒川 知南、Mary Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      第75回日本薬理学会西南部会 (2022.10.01 高知県民文化ホール(高知))
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Presentation] AKI to CKD transition モデルマウスに対する微弱パルス電流と温熱の同時印加の効果2022

    • Author(s)
      津波古 遥希、寺本 啓祐、加世田 将大、Piruzyan Mariam、岩上 長巨、荒川 知南、Marry Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      第39回日本薬学会九州山口支部大会 (2022.10.19-20 長崎国際大学(長崎))
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Presentation] 可逆的 Keap1 阻害薬による慢性腎臓病モデルマウスの病態改善効果2022

    • Author(s)
      堀園 潤、加世田 将大、三宮 裕也、桑水流 淳、小木 彩矢佳、佐々木亮子、砂本 秀利、吹屋 洋彦、西山 勇人、小山 結実、 Mary Ann Suico、奈良 太、首藤 剛、大沼 和弘、甲斐 広文
    • Organizer
      第75回日本薬理学会西南部会 (2022.10.01 高知県民文化ホール(高知))
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Presentation] NanoLuciferase 技術を用いた HTS 評価系による新規 Alport 症候群治療薬候補化合物の同定2022

    • Author(s)
      桑水流 淳、加世田 将大、三宮 裕也、堀園 潤、津波古 遥希、小山 結実、尾脇 あいみ、佐藤 諒一、白神 正博、Mary Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      第16回次世代を担う若手のための医療薬科学シンポジウム (2022.10.29-30 和歌山県立医科大学(和歌山))
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Presentation] Efficacy of Keap1-Nrf2 protein-protein interaction inhibitor for progressive phenotype in Alport syndrome mouse model2022

    • Author(s)
      Shota Kaseda, Yuya Sannomiya, Jun Horizono, Jun Kuwazuru, Sayaka Ogi, Ryoko Sasaki, Hidetoshi Sunamoto, Hirohiko Fukiya, Hayato Nishiyama, Misato Kamura, Saki Niinou, Mary Ann Suico, Futoshi Nara, Tsuyoshi Shuto, Kazuhiro Onuma, Hirofumi Kai
    • Organizer
      第57回日本小児腎臓病学会学術集会(2022.05.27-28 沖縄コンベンションセンター(沖縄))
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Presentation] 遺伝性腎疾患Alport症候群におけるコラーゲン受容体DDR2の阻害による腎病態への影響についての基礎的検討2022

    • Author(s)
      三宮 裕也、加世田 将大、嘉村 美里、桑水流 淳、Suico Mary Ann、首藤 剛、甲斐 広文
    • Organizer
      日本薬学会 第142回年会 オンライン学会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] Mild electrical stimulation and heat shock suppress acute kidney injury (AKI) to chronic kidney disease (CKD) transition2022

    • Author(s)
      Haruki Tsuhako, Keisuke Teramoto, Shota Kaseda, Piruzyan Mariam, Tatsuo Iwakami, Tina Arakawa, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai
    • Organizer
      第96回日本薬理学会年会 (2022.11.30-12.3 パシフィコ横浜 (神奈川))
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Presentation] Renal protective effect of a novel non-covalent Keap1-Nrf2 inhibitor in chronic kidney disease2022

    • Author(s)
      堀園 潤、加世田 将大、三宮 裕也、桑水流 淳、小木 彩矢佳、佐々木亮子、砂本 秀利、吹屋 洋彦、西山 勇人、小山 結実、Mary Ann Suico、奈良 太、首藤 剛、大沼 和弘、甲斐 広文
    • Organizer
      第16回次世代を担う若手のための医療薬科学シンポジウム (2022.10.29-30 和歌山県立医科大学(和歌山))
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Presentation] 糸球体障害を呈する慢性腎臓病モデルマウスに対する Keep1-Nrf2 タンパク質間相互作用阻害薬の有効性2022

    • Author(s)
      加世田 将大、三宮 裕也、堀園 潤、桑水流 淳、Mary Ann Suico、小木 彩矢佳、佐々木 亮子、砂本 秀利、吹屋 洋彦、西山 勇人、嘉村 美里、奈良 太、首藤 剛、大沼 和弘、甲斐 広文
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 新規Keap1阻害薬の慢性腎臓病に対する病態改善効果2022

    • Author(s)
      堀園潤、加世田将大、三宮裕也、 桑水流淳、 小木彩矢佳、 佐々木亮子、砂本秀利、 吹屋洋彦、西山勇人、小山 結実、Mary Ann Suico、奈良太、 首藤剛、大沼和弘、甲斐広文
    • Organizer
      次世代を担う若手のための創薬・医療薬理シンポジウム2022 (2022.08.27 静岡県立大学(静岡))
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Presentation] 慢性腎臓病における Keap1-Nrf2 タンパク質間相互作用阻害薬の有用性2022

    • Author(s)
      堀園 潤、加世田 将大、三宮 裕也、桑水流 淳、小木 彩矢佳、佐々木亮子、砂本 秀利、吹屋 洋彦、西山 勇人、小山 結実、Mary Ann Suico、奈良 太、首藤 剛、大沼 和弘、甲斐 広文
    • Organizer
      第21回・次世代を担う若手のためのファーマ・バイオフォーラム2022 (2022.09.03-04 名古屋市立大学薬学部(名古屋))
    • Data Source
      KAKENHI-PROJECT-23K24072
  • [Presentation] The role of discoidin domain receptor 2 in the renal dysfunction of Alport syndrome mouse mode2021

    • Author(s)
      Yuya Sannomiya, Shota Kaseda, Misato Kamura, Jun Kuwazuru, Saki, Niino, Tsuyoshi Shuto, Mary Ann Suico, Hirofumi Kai
    • Organizer
      The 23rd Korea-Japan Joint Seminar on Pharmacology (KJJSP) Online
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 遺伝性糸球体腎炎 Alport 症候群モデルマウスに対する可逆的 Keap1 阻害剤の腎保護効果2021

    • Author(s)
      堀園 潤、加世田 将大、三宮 裕也、桑水流 淳、小木 彩矢佳、佐々木 亮子、砂本 秀利、吹屋 洋彦、西山 勇人、嘉村 美里、新納 咲紀、小山 結実、Mary Ann Suico、奈良 太、首藤 剛、大沼 和弘、甲斐 広文
    • Organizer
      第38回日本薬学会九州山口支部大会 オンライン学会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 可逆的Keap1阻害剤は遺伝性糸球体腎炎Alport症候群モデルマウスの腎病態を改善する2021

    • Author(s)
      加世田 将大、三宮 裕也、桑水流 淳、小木 彩矢佳、佐々木 亮子、砂本 秀利、吹屋 洋彦、西山 勇人、嘉村 美里、新納 咲紀、堀園 潤、小山 結実、Suico Mary Ann、大沼 和弘、奈良 太、首藤 剛、甲斐 広文
    • Organizer
      日本薬学会 第141回年会 オンライン学会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 遺伝性腎疾患Alport症候群の原因タンパク質を標的とした新規治療薬候補の同定及び薬効解析2021

    • Author(s)
      桑水流 淳、加世田 将大、三宮 裕也、新納 咲紀、堀園 潤、小山 結実、Marry Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      日本薬学会 第141回年会 オンライン学会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 遺伝性糸球体腎炎 Alport 症候群モデルマウスに対する可逆的 Keap1 阻害剤の腎保護効果2021

    • Author(s)
      堀園 潤、加世田 将大、三宮 裕也、桑水流 淳、小木 彩矢佳、佐々木 亮子、砂本 秀利、吹屋 洋彦、西山 勇人、嘉村 美里、新納 咲紀、小山 結実、Mary Ann Suico、奈良 太、首藤 剛、大沼 和弘、甲斐 広文
    • Organizer
      第12回 トランスポーター研究会 九州部会 オンライン学会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] アンメットメディカルニーズの高い難治性疾患への挑戦 - ミッションに基づくアカデミア天然物創薬2020

    • Author(s)
      首藤 剛、Marry Ann Suico、Devkota Anjana、小澤 享子、三隅 将吾、岸本 直樹、河原 哲平、人羅 勇気、塚本 佐知子、甲斐 広文、菊池 正彦
    • Organizer
      第73回 日本薬理学会西南部会 オンライン学会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 遺伝性腎疾患Alport症候群に対する新規作用機序を有する薬物の同定及び薬効解析2020

    • Author(s)
      桑水流 淳、加世田 将大、三宮 裕也、新納 咲紀、堀園 潤、小山 結実、Marry Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      第73回 日本薬理学会西南部会 オンライン学会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 変異Ⅳ型コラーゲンの輸送・分泌を促進する遺伝性腎疾患Alport症候群の新規治療薬2020

    • Author(s)
      桑水流 淳、加世田 将大、三宮 裕也、新納 咲紀、堀園 潤、小山 結実、Mary Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      第15回 トランスポーター研究会年会 オンライン学会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] Recent progress on high throughput screening-based search for therapeutic reagents against Alport syndrom2019

    • Author(s)
      Hirofumi Kai, Mary Ann Suico, Tsuyoshi Shuto, Misato Kamura, Jun Kuwazuru, Haruka Kojima, Kohei Omachi
    • Organizer
      The 2019 International workshop on Alport Syndrome Siena, Italy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 各種アミロイドーシスに対するアミロイドブレーカーの探索研究2019

    • Author(s)
      佐々木 亮子、寺西 ゆり子、帖佐 圭佑、植田 光晴、橋本 那美、山縣 章正、中野 義雄、福島 友太朗、小澤 享子、Mary Ann Suico、首藤 剛、安東 由喜雄、甲斐 広文
    • Organizer
      第19回次世代創薬研究者養成塾ポスターフェス2019
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 閉塞性肺疾患と亜鉛の意外な関係性~亜鉛トランスポーターの観点から2019

    • Author(s)
      首藤 剛、亀井 竣輔、Mary Ann Suico、甲斐 広文
    • Organizer
      第19回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] Drug discovery for Alport Syndrome by screening of natural products library2019

    • Author(s)
      Mary Ann Suico, Jun Kuwazuru, Kohei Omachi, Misato Kamura, Tsuyoshi Shuto, Hirofumi Kai
    • Organizer
      第19回次世代創薬研究者養成塾ポスターフェス2019
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 慢性閉塞性肺疾患モデルに対する甲状腺ホルモン(T3)経気管投与の影響2019

    • Author(s)
      高橋 宜暉、藤川 春花、中嶋 竜之介、江藤 結花、那須 葵、Marry Ann Suico、甲斐 広文、首藤 剛
    • Organizer
      第11回 トランスポーター研究会九州部会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 遺伝性腎炎Alport症候群に対する代謝異常の改善を企図したmetforminの効果2019

    • Author(s)
      加世田 将大、大町 紘平、横田 翼、嘉村 美里、寺本 啓祐、小嶋 遥、桑水流 淳、大槻 純男、Mary Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      第27回クリニカルファーマシーシンポジウム
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] COPDモデルマウスに対する甲状腺ホルモン経気管投与の影響2019

    • Author(s)
      高橋 宜暉、藤川 春花、中嶋 竜之介、江藤 結花、那須 葵、Marry Ann Suico、甲斐 広文、首藤 剛
    • Organizer
      第83回日本呼吸器学会・日本結核病学会 日本サルコイドーシス/肉芽腫性疾患学会 九州支部 秋季学術講演会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] メリンジョ種子抽出物(MSE)による慢性閉塞性肺疾患モデルマウスの肺病態抑制作用2019

    • Author(s)
      那須 葵、川上 太聖、藤川 春花、中嶋 竜之介、江藤 結花、野原 寛文、鬼木 健太郎、Mary Ann Suico、猿渡 淳二、甲斐 広文、首藤 剛
    • Organizer
      第72回 日本薬理学会西南部会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] Alport 症候群におけるコラーゲン受容体 discoidin domain receptor 2の機能解明に向けた基礎的検討2019

    • Author(s)
      三宮 裕也、加世田 将大、嘉村 美里、桑水流 淳、Mary Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      第72回 日本薬理学会西南部会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 慢性閉塞性肺疾患モデルに対する甲状腺ホルモン(T3)経気管投与の影響2019

    • Author(s)
      高橋 宜暉、藤川 春花、中嶋 竜之介、江藤 結花、那須 葵、Marry Ann Suico、甲斐 広文、首藤 剛
    • Organizer
      第36回日本薬学会九州支部大会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] メリンジョ種子抽出物(MSE)による慢性閉塞性肺疾患モデルマウスの肺病態抑制作用2019

    • Author(s)
      那須 葵、川上 太聖、藤川 春花、中嶋 竜之介、江藤 結花、野原 寛文、鬼木 健太郎、Mary Ann Suico、猿渡 淳二、甲斐 広文、首藤 剛
    • Organizer
      第11回 トランスポーター研究会九州部会
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] Therapeutic potential of metformin in novel COPD mouse model with diffuse-type emphysema2019

    • Author(s)
      Ryunosuke Nakashima, Hirofumi Nohara, Shunsuke Kamei, Haruka Fujikawa, Kasumi Maruta, Taisei Kawakami, Yuka Eto, Noriki Takahashi, Aoi Nasu, Mary-Ann Suico, Hirofumi Kai, Tsuyoshi Shuto
    • Organizer
      ASCB|EMBO 2019 meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03379
  • [Presentation] 微弱パルス電流と温熱の同時印加はimiquimod誘導性乾癬モデルにおけるケラチノサイトの過剰増殖を抑制する2017

    • Author(s)
      連川 雄, 甲斐 友佳理, 中野 義雄, 森田 光咲, 高田 雅文, 森内 将貴, Mariamu Piruzyan, Mary Ann Suico, 首藤 剛, 甲斐 広文
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] タウリンは TRPV1 を阻害し,線虫において酸化ストレス抑制作用を示す2017

    • Author(s)
      森内 将貴, 中野 義雄, 連川 雄, Mariam Piruzyan, 高田 雅文, 森田 光咲, Niraj Chaudhry, Mary Ann Suico, 首藤 剛, 甲斐 広文
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] タンパク質フォールディングは遺伝性腎炎アルポート症候群の新たな標的となり得るか2017

    • Author(s)
      甲斐 広文, 大町 紘平, Mary Ann Suico, 首藤 剛
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] 最適化された微弱パルス電流と温熱の臨床応用2016

    • Author(s)
      甲斐 広文
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2016-03-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] 微弱パルス電流及び温熱の同時印加はimiquimod誘導性乾癬モデルにおける表皮の肥厚化を抑制する2016

    • Author(s)
      連川 雄, 甲斐 友佳理, 中野 義雄, 森田 光咲, 高田 雅文, 森内 将貴, Mariamu Piruzyan, Mary Ann Suico, 首藤 剛, 甲斐 広文
    • Organizer
      第33回日本薬学会九州支部大会
    • Place of Presentation
      鹿児島大学 郡元キャンパス
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] 遺伝性プロテインミスフォールディング病に対する創薬2016

    • Author(s)
      甲斐 広文
    • Organizer
      第37回日本臨床薬理学会学術総会
    • Place of Presentation
      米子コンベンションセンター
    • Year and Date
      2016-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] Mild electrical stimulation with heat shock suppresses skin hyperplasia in imiquimod-induced psoriasis model.2016

    • Author(s)
      Tsurekawa Y, Kai Y, Morita M, Takada M, Moriuchi M, Okita G, Suico MA, Shuto T, Kai H
    • Organizer
      16th International Congress of Immunology
    • Place of Presentation
      Merborne, Australia
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] 乾癬における最適化微弱電流の病態改善効果に関する研究2016

    • Author(s)
      連川 雄, 森内 将貴, 沖田 剛, 中野 義雄, Mariam Piruzyan, 高田 雅文, 森田 光咲, Mary Ann Suico, 首藤 剛, 甲斐 広文
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] 遺伝性疾患患者由来iPS細胞を用いた遺伝子治療と再生医療;遺伝性呼吸器疾患嚢胞性繊維症(Cystic Fibrosis, CF)患者由来iPS細胞のゲノム修復及び機能的気道上皮細胞への分化誘導2016

    • Author(s)
      鈴木 伸悟、R. Geoffrey Sargent、帖佐 圭佑、Beate Illek、Horst Fischer、Alaleh Eamaeili-Shandiz、首藤 剛、甲斐 広文、Yuet. W Kan、Dieter.C Gruenert
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] 6-benzoyl-2-hydroxy-1H-benzo[de]isoquin oline-1,3(2H)-dione is a novel transthyretin stabilizer for familial amyloid polyneuropathy2015

    • Author(s)
      S. Takaki, K. Chosa, T. Yokoyama, Y. Teranishi, Y. Wakita, T. Sato, M. Suico, T. Shuto, M. Mizuguchi, H. Kai
    • Organizer
      International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
    • Place of Presentation
      熊本大学(熊本)
    • Year and Date
      2015-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] Characterization of the intracellular behavior of COL4A5 and clarification of molecular mechanism of alport syndrome2015

    • Author(s)
      K. Omachi, M. Kamura, K. Teramoto, R. Fukuda, M. Suico, T. Shuto, H. Kai
    • Organizer
      52nd ERA-EDTA CONGRESS LONDON 2015
    • Place of Presentation
      London(UK)
    • Year and Date
      2015-05-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] The Immunosuppressive Effect of Mild Electrical Stimulation is a Promising Therapy for Inflammation2015

    • Author(s)
      Mariam Piruzyan, Ihori Shitanda, Yuichiro Shimauchi, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai
    • Organizer
      第68回日本薬理学会西南部会
    • Place of Presentation
      海峡メッセ下関(山口)
    • Year and Date
      2015-11-21
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] Hsp47によるTTRタンパク質の細胞内品質管理機構の解明2015

    • Author(s)
      脇田 有梨子、山川 瑠斐子、帖佐 圭佑、高木 舜、寺西 ゆり子、佐藤 卓史、Mary Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      第32回日本薬学会九州支部大会
    • Place of Presentation
      九州保健福祉大学(宮崎)
    • Year and Date
      2015-11-28
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] The immunosuppressive effect of mild electrical stimulation via NFAT pathway is a promising therapeutic approach for inflammation2015

    • Author(s)
      Mariam Piruzyan, Ihori Shitanda, Yuichiro Shimauchi, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai
    • Organizer
      第32回日本薬学会九州支部大会
    • Place of Presentation
      九州保健福祉大学(宮崎)
    • Year and Date
      2015-11-28
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] Molecular mechanism of the intracellular quality control of TTR by Hsp472015

    • Author(s)
      Y. Wakita, R. Yamakawa, K. Chosa, S. Takaki, Y. Teranishi, T. Sato, M.Suico, T. Shuto, H. Kai
    • Organizer
      2015 cell biology ascb annual meeting
    • Place of Presentation
      San Diego(USA)
    • Year and Date
      2015-12-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] Beneficial effects and the molecular mechanisms of specific mild electrical stress as physical medicine2015

    • Author(s)
      H. Kai, T. Kondo, M.A. Suico, T. Shuto E. Araki
    • Organizer
      International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
    • Place of Presentation
      熊本大学薬学部(熊本)
    • Year and Date
      2015-10-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] The immunosuppressive effect of mild electrical stimulation via NFAT pathway is a promising therapeutic approach for inflammation2015

    • Author(s)
      M. Piruzyan, I. Shitanda, Y. Shimauchi, M. Suico, T. Shuto, H. Kai immunosuppressive effect of mild electrical stimulation via NFAT pathway is a promising therapeutic approach for inflammation
    • Organizer
      International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
    • Place of Presentation
      熊本大学薬学部(熊本)
    • Year and Date
      2015-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] The molecular quality control of TTR by Hsp472015

    • Author(s)
      Y. Wakita, R. Yamakawa, K. Chosa, S. Takaki, Y. Teranishi, T. Sato, S. Ann, T. Shuto, H. Kai
    • Organizer
      International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
    • Place of Presentation
      熊本大学(熊本)
    • Year and Date
      2015-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] Mild pulse electrical stimulation at high frequency (5500 pps) suppresses brain inflammation related to Alzheimer’s disease.2015

    • Author(s)
      G. Okita, H. Kai
    • Organizer
      第44回日本免疫学会学術集会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] Hsp47によるTTRタンパク質の細胞内品質管理機構の解明2015

    • Author(s)
      脇田 有梨子、山川 瑠斐子、帖佐 圭佑、高木 舜、寺西 ゆり子、佐藤 卓史、Mary Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      第37回生体膜と薬物の相互作用シンポジウム2015
    • Place of Presentation
      熊本大学薬学部(熊本)
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] Hsp47によるTTRタンパク質の細胞内品質管理機構の解明2015

    • Author(s)
      脇田 有梨子、山川 瑠斐子、帖佐 圭佑、高木 舜、寺西 ゆり子、佐藤 卓史、Mary Ann Suico、首藤 剛、甲斐 広文
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] High throughput screening-based identification of transthyretin stabilizers for familial amyloid polyneuropathy2015

    • Author(s)
      Y. Teranishi, K. Chosa, T. Shuto, S. Takaki, Y. Wakita, T. Sato, M. Suico, T. Yamashita, H. Kai
    • Organizer
      International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
    • Place of Presentation
      熊本大学(熊本)
    • Year and Date
      2015-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] バーチャルスクリーニングシステムを活用した、家族性アミロイドポリニューロパチー原因タンパク質 TTR の四量体安定化剤の同定2015

    • Author(s)
      高木 舜、帖佐 圭佑、横山 武司、佐藤 卓史、Mary Ann Suico、寺西 ゆり子、首藤 剛、水口 峰之、甲斐 広文
    • Organizer
      第37回生体膜と薬物の相互作用シンポジウム2015
    • Place of Presentation
      熊本大学薬学部(熊本)
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] 遺伝性腎炎Alport症候群の病態進行抑制因子および原因タンパク質に焦点を当てた新規治療薬の開発2015

    • Author(s)
      大町 紘平, 福田 亮介, 嘉村 美里, 寺本 啓祐, 横田 翼, 本村 敬士, 山川 瑠斐子, Mary Ann Suico, 首藤 剛, 甲斐 広文
    • Organizer
      第6回分子腎臓フォーラム
    • Place of Presentation
      グランフロント大阪(大阪)
    • Year and Date
      2015-09-05
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] The Effect and Mechanism of Mild Electrical Stimulation on Pro-inflammatory Cytokines in vivo and in vitro2015

    • Author(s)
      Mariam Piruzyan, Ihori Shitanda, Yuichiro Shimauchi, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] Mild electrical stimulation suppresses IL22 mRNA expression in imiquimod-induced psoriasis mouse model2015

    • Author(s)
      Y. Tsurekawa, M. Suico, M. Moriuchi, G. Okita, Y. Nakano, M. Piruzyan, M. Takada, M. Morita, T. Shuto, H. Kai
    • Organizer
      International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
    • Place of Presentation
      熊本大学薬学部(熊本)
    • Year and Date
      2015-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12514
  • [Presentation] Low-intensity direct electrical current stress suppresses pro-inflammatory cytokines expression via inhibition of multiple signaling pathways2013

    • Author(s)
      I. Shitanda, S. Matsuyama, K. Mitsutake, R. Fukuda, Y. Kai, M. Suico, T. Shuto, H. Kai
    • Organizer
      2013 ASCB Annual Meeting
    • Place of Presentation
      The New Orleans Ernest N. Morial Convention Center, New Orleans, Lousiana,USA
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] Physical Medicine を科学する~新たな医療機器の研究開発~2013

    • Author(s)
      甲斐 広文
    • Organizer
      熊本和光ライフサイエンスフォーラム
    • Place of Presentation
      熊本大学医学部(熊本県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] The endoplasmic reticulum-oriented drug development for transthyretin familial amyloid polyneuropathy2013

    • Author(s)
      Keisuke Chosa , Ruiko Yamakawa , Takashi Sato , Takeshi Yokoyama , Mineyuki Mizuguchi , Mary Ann Suico ,Tsuyoshi Shuto , Hirofumi Kai
    • Organizer
      IXth International Symposium on Familial Amyloidotic Polyneuropathy
    • Place of Presentation
      Auditorio do Centro de Convencoes Antonio Seabra Moggi,Rio de Janeiro, Brazil
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] 翻訳後 N型糖鎖修飾を介した小胞体品質管理機構による家族性アミロイドーシスの発症性制御機 構 の 解 明2013

    • Author(s)
      佐藤 卓史, 庄 美里, スイコ メリーアン, 首藤 剛, 甲斐 広文
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 遺伝性糸球体腎疾患アルポト症候群に対する新たなphysical medicine の腎病態改善効果2013

    • Author(s)
      甲斐 友佳理, 古賀 友紹, 福田 亮介, 古賀 沙緒里, Mary Ann SUICO,小山 皓介, 松山 真吾, 佐藤 卓史,首藤 剛, 甲斐 広文
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      パシフィコ横浜,(横浜)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] Physical Medicine を 科学する~新たな医療機器の研究開発~2013

    • Author(s)
      甲斐 広文
    • Organizer
      熊本和光ライフサイエンスフォーラム
    • Place of Presentation
      熊本大学(熊本)
    • Year and Date
      2013-02-22
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 遺伝性糸球体腎疾患アルポート症候群に対する新たな physical medicine の腎病態改善効果2013

    • Author(s)
      甲斐 友佳理
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] The endoplasmic reticulum-oriented drug development for familial amyloid polyneuropathy2013

    • Author(s)
      K. Chosa, R. Yamakawa, T. Sato, T. Yokoyama, M. Mizuguchi, M. Suico, T. Shuto, H. Kai
    • Organizer
      2013 ASCB Annual Meeting
    • Place of Presentation
      The New Orleans Ernest N. Morial Convention Center, New Orleans, Lousiana,USA
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] Specific pulse-width mild electrical stimulation induces p53 activation via p38 MAPK and ameliorates LPS-induced inflammatory cytokine response2013

    • Author(s)
      R. Fukuda, K. Omachi, M. A. Suico, K. Koyama, Y. Kai, S. Matsuyama, K. Mitsutake, S. Morino-Koga, T. Shuto, H. Kai.
    • Organizer
      15th International congress of immunology
    • Place of Presentation
      Mico Milano Congressi, Milano, ITALY
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] 慢性腎疾患 Alport syndrome モデルマウスを用いた癌抑制遺伝子 p53 の腎保護的機能 の 解 明2013

    • Author(s)
      福田 亮介, 小山 皓介, 古賀 友紹,甲斐 友佳理, スイコ メリーアン, 大町 紘平, 本村 敬士, 首藤 剛, 甲斐広文
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] Specific pulse width mild electrical stress increases stress resistance and suppresses fat accumulation via activation of LKB1-AMPK signaling pathway.2013

    • Author(s)
      Shingo Matsuyama, Masataka Moriuchi, Mary Ann Suico, Tsuyoshi Shuto and Hirofumi Kai
    • Organizer
      VI International Congress on Stress Proteins in Biology and Medicine
    • Place of Presentation
      Edge conference Centre, Sheffield, UK
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] Beneficial effects and their molecular mechanisms of specific pulse width mild electrical stress as physical medicine2013

    • Author(s)
      H. Kai, T. Kondo, M.A. Suico, T. Shuto, E. Araki
    • Organizer
      VI International Congress on Stress Proteins in Biology and Medicine
    • Place of Presentation
      Edge conference Centre, Sheffield, UK
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] 新規 phisical medicine 微弱パルス電流のLKB1-AMPK 経路活性化を介した脂肪蓄積抑制効果およびストレス耐性付与効果2013

    • Author(s)
      松山 真吾, 岡本 有加, 四反田 伊穂李, 大町 紘平, 森内 将貴, MaryAnn SUICO, 首藤 剛, 甲斐 広文
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      パシフィコ横浜,(横浜)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 異常な構造を持つ分泌タンパク質の新たな小胞体品質管理機構2013

    • Author(s)
      庄 美里, 佐藤 卓史, 帖佐 圭佑,山川 瑠斐子, スイコ メリーアン, 首藤剛, 甲斐 広文
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 新たなPhysical Medicine;最適化された物理ストレスを活用した医療(予防)機器2013

    • Author(s)
      甲斐 広文
    • Organizer
      第11回維持透析患者の補完・代替医療研究会
    • Place of Presentation
      名古屋ルーセントタワー(愛知)
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] Mild electrical stimulation with heat shock ameliorates nephritis and proteinuria in mouse model of X-linked alport syndrome2013

    • Author(s)
      Y. Kai, T. Koga, R. Fukuda, S. Morino-Koga, M. A. Suico, K. Koyama, T. Sato, T. Shuto, H. Kai
    • Organizer
      15th International congress of immunology
    • Place of Presentation
      Mico Milano Congressi, Milano, ITALY
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] Crucial role of basal p53 in attenuation of inflammation and fibrosis in hereditary glomerular nephritis, Alport syndrome2013

    • Author(s)
      R. Fukuda, K. Koyama, T. Koga, Y. Kai, K. Omachi, K. Motomura, M. A. Suico, T. Shuto, H. Kai
    • Organizer
      15th International congress of immunology
    • Place of Presentation
      Mico Milano Congressi, Milano, ITALY
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] STT3B-dependentposttranslational N-glycosylation as asurveillance system for secretoryprotein2012

    • Author(s)
      Kai H, Sato T, Sho M, Sako Y, M. A. Suico, Shuto T
    • Organizer
      Quality Control FromMolecules to Organelles
    • Place of Presentation
      EMB Advenced TrainingCentre,Heidelberg(Germany)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 薬理学的アプローチによる新たなPhysical Medicineの研究開発2012

    • Author(s)
      甲斐 広文
    • Organizer
      第65回日本薬理学会西南部会
    • Place of Presentation
      熊本大学薬学部(熊本県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] p53 regulates theEts transcription factor MEF/Elf4 viaMDM22012

    • Author(s)
      M. Suico, R. Miyakita, K. Koyama, M.Taura,T. Shuto, H. Kai
    • Organizer
      ASCB 2012 Annual Meeting
    • Place of Presentation
      Moscone Center, SanFrancisco(USA)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 変異トランスサイレチンの翻訳後 N 型糖鎖修飾の意義とその制御因子の探索2012

    • Author(s)
      庄 美里, 佐藤 卓史, 西頭 英起,小亀 浩市, 金子 雅幸, 和田 郁夫,メ リー アン スイ コ, 首 藤 剛, 甲斐広文
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場 (福岡)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein2012

    • Author(s)
      Hirofumi Kai
    • Organizer
      Quality Control From Molecules to Organelles
    • Place of Presentation
      Heidelberg, Germany
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] Mild electrical stimulation andheat shock ameliorates progressiveproteinuria and renal inflammation inmouse model of chronic kidney diseases2012

    • Author(s)
      Hirofumi Kai, Tomoaki Koga, Yukari Kai,Saori M. Koga, Mary Ann Suico, TsuyoshiShuto
    • Organizer
      ICHO&JCTM
    • Place of Presentation
      ハイアットリージェンシー京都(京都)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 慢性腎疾患 Alport syndrome モデルマウスを用いた癌抑制遺伝子 p53 の腎保護的機能の解明2012

    • Author(s)
      福田 亮介, 小山 皓介, 古賀 友紹,甲斐 友佳理, Mary Ann Suico, 首藤 剛,甲斐 広文
    • Organizer
      第65回 日本薬理学会西南部会
    • Place of Presentation
      熊本大学(熊本)
    • Year and Date
      2012-11-23
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 新しい薬効評価モデル、気道粘液分泌亢進トランスジェニックマウスと去痰薬の再評価2012

    • Author(s)
      甲斐 広文
    • Organizer
      日本肺サーファクタン ト・ 界面医 学会 第48回学 術研究 会
    • Place of Presentation
      熊本市国際交流会館 (熊本)
    • Year and Date
      2012-10-27
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 微弱パルス電流の LKB1-AMPK 経路活性化を介したストレス耐性付与および脂肪蓄積抑制効果)2012

    • Author(s)
      松山 真吾, 岡本 有加, 四反田 伊穂李, 大町 紘平, 森内 将貴, スイコ メリーアン, 首藤 剛, 甲斐 広文
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 遺伝性腎疾患および糖尿病性腎症に対する新たなphysical medicineの腎病態改善効果2012

    • Author(s)
      甲斐 広文
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(北海道)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] Specifiedpulse-width mild electrical stimulationinduces p53 phosphorylation andtranscriptional activation2012

    • Author(s)
      Ryosuke Fukuda, Kosuke Koyama, KoheiOmachi, Yukari Kai, Shingo Matsuyama,Yuka Okamoto, Mary A Suico, TsuyoshiShuto, Hirofumi Kai
    • Organizer
      ICHO&JCTM
    • Place of Presentation
      ハイアットリージェンシー京都(京都)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 薬理学的アプローチによる新たな Physical Medicine の研究開発2012

    • Author(s)
      甲斐 広文
    • Organizer
      第65回日本薬理学会西南部会
    • Place of Presentation
      熊本大学(熊本
    • Year and Date
      2012-11-23
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] Mild electrical stimulation and heat shock ameliorates progressive proteinuria and renal inflammation in mouse model of chronic kidney diseases2012

    • Author(s)
      甲斐 広文
    • Organizer
      ICHO&JCTM 2012
    • Place of Presentation
      ハイアットリージェンシー京都(京都府)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 新しい薬効評価モデル、気道粘液分泌亢進トランスジェニックマウスと去痰薬の再評価2012

    • Author(s)
      甲斐 広文
    • Organizer
      日本肺サーファクタント・界面医学会 第48回学術研究会
    • Place of Presentation
      熊本市国際交流会館(熊本)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 遺伝性腎疾患および糖尿病性腎症に対する新たな physical medicineの腎病態改善効果2012

    • Author(s)
      甲斐 広文
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      北海道大学(北海道)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 遺伝性腎疾患および糖尿病性腎症に対する新たなphysical medicineの腎病態改善効果2012

    • Author(s)
      甲斐広文
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(北海道)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] ABCトランスポーターABCG5およびABCG8の小胞体における翻訳後発現制御機構の解明2011

    • Author(s)
      鈴木伸悟, 首藤剛, 佐藤卓史, 金子雅幸, Mary Ann Suico, 甲斐広文
    • Organizer
      第5回トランスポーター研究会九州部会
    • Place of Presentation
      ホテルJALシティ宮崎(宮崎)
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] Posttranslational N-glycosylation regulates the quality control of transthyretin in the ER2011

    • Author(s)
      T.Sato, Y.Sako, M.Sho, M.Momohara, H.Nishitoh, K.Kokame, M.Kaneko, M.A.Suico, T.Shuto, T.Koga, S.Morino-Koga, I.Wada, H.Kai
    • Organizer
      8th International Symposium on Familial Amyloidotic Polyneuropathy
    • Place of Presentation
      熊本大学(熊本)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] Physical medicine -Basic and translational research on conditioned physical stress-2011

    • Author(s)
      Hirofumi Kai, Tatsuya Kondo, Saori Koga-Morino, Eiichi Araki
    • Organizer
      第34回日本分子生物学会年会(招待講演)
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] ストレス耐性付与および脂肪蓄積抑制作用を有する新たなphysical medicine2011

    • Author(s)
      松山 真吾、矢野 脩一郎、古賀(森野)佐緒里、島内 裕一郎、岡本 友加、四反田 伊穂李、メリーアン スイコ、首藤剛、甲斐 広文
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福 岡 大 学(福岡)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] Physical medicine-Basic and translational research on conditioned physical stress-2011

    • Author(s)
      Hirofumi Kai, Tatsuya Kondo, Saori Koga-Morino, Eiichi Araki
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 翻訳後 N 型糖鎖修飾によるトランスサイレチンの新規小胞体品質管理機構2011

    • Author(s)
      庄 美里、佐藤 卓史、迫 康弘、桃原真美子、西頭 英起、金子 雅幸、メリーアン スイコ、首藤 剛、甲斐 広文
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大学薬学部(福岡)
    • Year and Date
      2011-11-14
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] Physicalmedicine -Basic and translationalresearch on conditioned physicalstress-2011

    • Author(s)
      Hirofumi Kai, Tatsuya Kondo, SaoriKoga-Morino, Eiichi Araki
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 糖鎖型および脱糖鎖型BCRPタンパク質のDerlin-1による負の翻訳後発現調節2011

    • Author(s)
      首藤剛, 杉山崇, 鈴木伸悟, 佐藤卓史, 古賀友紹, Mary Ann Suico, 楠原洋之, 杉山雄一, 甲斐広文
    • Organizer
      第5回トランスポーター研究会九州部会
    • Place of Presentation
      ホテルJALシティ宮崎(宮崎)
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] ABCトランスポーター ABCG5 および ABCG8 の小胞体における翻訳後発現制御機構の解明2011

    • Author(s)
      鈴木 伸悟,首藤 剛,佐藤 卓史,金子 雅幸,Mary Ann Suico,甲斐 広文
    • Organizer
      第5回トランスポーター研究会九州部会
    • Place of Presentation
      ホテル JAL シティ宮崎(宮崎)
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 糖鎖型および脱糖鎖型 BCRP タンパク質の Derlin-1による負の翻訳後発現調節2011

    • Author(s)
      首藤 剛,杉山 崇,鈴木 伸悟,佐藤 卓史,古賀 友紹,Mary Ann Suico,楠原 洋之,杉山 雄一,甲斐 広文
    • Organizer
      第5回トランスポーター研究会九州部会
    • Place of Presentation
      ホテル JAL シティ宮崎(宮崎)
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP in mammalian cells2011

    • Author(s)
      T.Sato, S.Susuki, M.Miyata, M.Momohara, M.A.Suico, T.Shuto, Y.Ando, H.Kai
    • Organizer
      8th International Symposium on Familial Amyloidotic Polyneuropathy
    • Place of Presentation
      熊本大学(熊本)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] アミロイド原性タンパク質の選択的分泌抑制を企図した創薬研究2011

    • Author(s)
      甲斐 広文
    • Organizer
      第5回薬学研究フォーラムin東京~九州からの情報発信~
    • Place of Presentation
      日本薬学会長井記念館(東京)
    • Year and Date
      2011-11-14
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding2011

    • Author(s)
      T.Sato, S.Susuki, M.A.Suico, M.Miyata, Y.Ando, M.Mizuguchi, T.Shuto, H.Kai
    • Organizer
      8th International Symposium on Familial Amyloidotic Polyneuropathy
    • Place of Presentation
      熊本大学(熊本)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] Endoplasmic reticulum quality control regulates the fate of transthyretin variants in the cell2011

    • Author(s)
      T.Sato, S.Susuki, M.A.Suico, M.Miyata, Y.Ando, M.Mizuguchi, T.Shuto, H.Kai
    • Organizer
      8th International Symposium on Familial Amyloidotic Polyneuropathy
    • Place of Presentation
      熊本大学(熊本)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] アミロイド原性タンパク質の選択的分泌抑制を企図した創薬研究2011

    • Author(s)
      甲斐広文
    • Organizer
      第5回薬学研究フォーラムin東京~九州からの情報発信~
    • Place of Presentation
      日本薬学会長井記念館(東京)
    • Year and Date
      2011-11-14
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] 糖鎖型および脱糖鎖型 BCRP タンパク質の Derlin-1による負の翻訳後発現調節2011

    • Author(s)
      首藤 剛,杉山 崇,鈴木 伸悟,佐藤 卓史,古賀 友紹,Mary Ann Suico,楠原 洋之,杉山 雄一,甲斐 広文
    • Organizer
      第6回トランスポーター研究会年会
    • Place of Presentation
      東北大学片平さくらホール(宮城県)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] HRD1-dependentendoplasmic reticulum-associateddegradation pathway is involved in theclearance of transthyretin variant2011

    • Author(s)
      M. Sho, T. Sato, Y. Sako, M. Momohara,H. Nishitoh, M. Kaneko, M. A. Suico, T.Shuto, H. Kai
    • Organizer
      5thInternational Congress on Stress Responsein Biology and Medicine
    • Place of Presentation
      Loews Hotel Le Concorde,Quebec(USA)
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 遺伝性腎疾患 alport 症候群に対する新たな physical medicine の腎病態改善効果2011

    • Author(s)
      甲斐 友佳理、古賀 友紹 、福田 亮介、古賀(森野) 沙緒里 、メリーアン スイコ、小山 皓介、佐藤 卓史、首藤 剛、甲斐 広文
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大学(福岡)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 翻訳後N型糖鎖修飾によるトランスサイレチンの新規小胞体品質管理機構2011

    • Author(s)
      庄美里、佐藤卓史、迫康弘、桃原真美子、西頭英起、金子雅幸、メリーアン スイコ、首藤剛、甲斐広文
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大学薬学部(福岡)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] The crystal structure of the green tea polyphenol(-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site2011

    • Author(s)
      M.Sho, M.Miyata, T.Sato, T.Nakmura, S.Ikemizu, M.Chirifu, M.Mizuguchi, Y.Suwa, H.Morioka, M.A.Suico, T.Shuto, Y.Yamagata, H.Kai
    • Organizer
      8th International Symposium on Familial Amyloidotic Polyneuropathy
    • Place of Presentation
      熊本大学(熊本)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] HRD1-dependent endoplasmic reticulum-associated degradation pathway is involved in the clearance of transthyretin variant2011

    • Author(s)
      M.Sho, T.Sato, Y.Sako, M.Momohara, H.Nishitoh, M.Kaneko, M.A.Suico, T.Shuto, H.Kai
    • Organizer
      5th International Congress on Stress Response in Biology and Medicine
    • Place of Presentation
      Loews Hotel Le Concorde, Quebec (USA)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] Intracellular trafficking of amyloidogenic TTR and its therapeutic implications2011

    • Author(s)
      甲斐広文
    • Organizer
      The 27th International Kumamoto Medical Bioscience Symposium
    • Place of Presentation
      熊本大学(熊本)
    • Year and Date
      2011-11-23
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] 糖尿病性腎症に対する新たな physical medicine の病態改善効果2011

    • Author(s)
      岡本 有加、古賀(森野) 沙緒里 、古賀 友紹 、大町 紘平、メリーアン スイコ、首藤 剛、甲斐 広文
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大学(福岡)
    • Data Source
      KAKENHI-PROJECT-23650269
  • [Presentation] 糖鎖型および脱糖鎖型BCRPタンパク質のDerlin-1による負の翻訳後発現調節2011

    • Author(s)
      首藤剛, 杉山崇, 鈴木伸悟, 佐藤卓史, 古賀友紹, Mary Ann Suico, 楠原洋之, 杉山雄一, 甲斐広文
    • Organizer
      第6回トランスポーター研究会年会
    • Place of Presentation
      東北大学片平さくらホール(宮城県)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] 遺伝性腎疾患alport症候群に対する新たなphysical medicineの腎病態改善効果2011

    • Author(s)
      甲斐友佳理、古賀友紹、福田亮介、古賀(森野)沙緒里、メリーアン スイコ、小山皓介、佐藤卓史、首藤剛、甲斐広文
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大学薬学部(福岡)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] Endoplasmic reticulum-associated degradation of transthyretin variant is mediated by HRD1 dependent pathway.2010

    • Author(s)
      Sako Y, Sato T, Momohara M, Sho M, Nishitoh H, Kaneko M, Mary Ann Suico, Shuto T, Kai H
    • Organizer
      The 50th Annual Meeting of the American Society for Cell Biology
    • Place of Presentation
      Pennsylvania Convention Center(USA)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] The role of HRD1 in intracellular trafficking of ATP binding cassette transporter G5 and G8.2010

    • Author(s)
      Suzuki S, Shuto T, Sato T, Takada T, Kaneko M, Suico MA, Koga T, Morino S, Suzuki H, Kai H
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      ホテル日航奈良
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] Posttranslational N-glycosylation is required for the efficient ERAD of transthyretin variants.2010

    • Author(s)
      Sato T, Sako Y, Momohara M, Sho M, Nishitoh H, Kaneko M, Mary Ann Suico, Shuto T, Wada I, Kai H
    • Organizer
      The 50th Annual Meeting of the American Society for Cell Biology
    • Place of Presentation
      Pennsylvania Convention Center(USA)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] Posttranslational regulation of ATP binding cassette transporter G5 and G8 by HRD12010

    • Author(s)
      Suzuki S, Shuto T, Sato T, Takada T, Kaneko M, Suico MA, Koga T, Morino S, Suzuki H, Kai H
    • Organizer
      ASCB 50th annual meeting Philadelphia
    • Place of Presentation
      PA, USA
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] Posttranslational N-glycosylation is required for the efficient ERAD of transthyretin variants.2010

    • Author(s)
      Sato T, Sako Y, Momohara M, Sho M, Nishitoh H, Kaneko M, Mary Ann Suico, Shuto T, Kai H
    • Organizer
      The 3rd International Symposium on Protein Community (ISPC-Nara2010)
    • Place of Presentation
      ホテル日航奈良(奈良)
    • Data Source
      KAKENHI-PUBLICLY-22020029
  • [Presentation] HRD1によるABCトランスポーターABCG5/8の翻訳後発現制御2010

    • Author(s)
      鈴木伸悟, 首藤剛, 新堀晶子, 佐藤卓史, 杉山崇, 高田龍平, 金子雅幸, Mary Ann Suico, 古賀友紹, 森野沙緒里, 鈴木洋史, 甲斐広文
    • Organizer
      日本薬学会第130回年会
    • Place of Presentation
      岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Presentation] Posttranslational regulation of ATP binding cassette transporter G5 and G8 by HRD12010

    • Author(s)
      Suzuki S, Shuto T, Sato T, Takada T, Kaneko M, Suico MA, Koga T, Morino S, Suzuki H, Kai H
    • Organizer
      Global COE-IMEG Joint Summer Retreat Seminar
    • Place of Presentation
      ホテルクリーンピア南阿蘇
    • Data Source
      KAKENHI-PROJECT-22390015
  • [Presentation] The role of Glu54 in transthyretin for protein stability, thyroxine binding and secretion from the cells.2009

    • Author(s)
      M.Miyata, T.Sato, M.Mizuguchi, T.Nakamura, S.Ikemizu, Y,Nabeshima, S.Susuki, Y.Suwa, H.Morioka, Y.Ando, M.A.Suico, T.Shuto, T.koga, Y.Yamagata, H.Kai
    • Organizer
      FASEB SUMMER RESEARCH CONFE RENCES, From unfolded proteins in the endplasmic reticulum to disease
    • Place of Presentation
      Vermont, USA
    • Data Source
      KAKENHI-PROJECT-20059027
  • [Presentation] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP.2009

    • Author(s)
      T.Sato, S.Susuki, M.Miyata, M.Momohara, Y.Sako, M.A.Suico, T.Shuto, H.Kai
    • Organizer
      Cell Stress Society International 2009
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-20059027
  • [Presentation] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by Bip in mammalian cells.2009

    • Author(s)
      T.Sato, S.Susuki, M.Miyata, M.Momohara, M.A. Suico, T.Shuto, Y.Ando, H.Kai
    • Organizer
      FASEB SUMMER RESEARCH CONFE RENCES, From unfolded proteins in the endplasmic reticulum to disease
    • Place of Presentation
      Vermont, USA
    • Data Source
      KAKENHI-PROJECT-20059027
  • [Presentation] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP2009

    • Author(s)
      T.Sato, S.Susuki, M.Miyata, M.Momohara, Y.Sako, M.A.Suico, T.Shuto, H.Kai
    • Organizer
      Cell Stress Society International 2009
    • Place of Presentation
      Sapporo, Japam
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Presentation] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP in mammalian cells2009

    • Author(s)
      T.Sato, S.Susuki, M.Miyata, M.Momohara, M.A.Suico, T.Shuto, Y.Ando, H.Kai
    • Organizer
      FASEB SUMMER RESEARCH CONFER ENCES, From unfolded proteins in the endoplasmic reticulum to disease
    • Place of Presentation
      Vermont, USA
    • Data Source
      KAKENHI-PROJECT-19390045
  • [Presentation] Screening of small compounds to develop endoplasmic reticulum-oriented drug for familial amyloid polyneuropathy.

    • Author(s)
      K. Chosa, S. Takaki, R. Yamakawa, Y. Wakita, Y. Teranishi, T. Sato, T. Yokoyama, M. Mizuguchi, M. Suico, T. Shuto, H. Kai
    • Organizer
      The 2014 ascb/ifcb Meeting
    • Place of Presentation
      Philadelphia(USA)
    • Year and Date
      2014-12-06 – 2014-12-10
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] 「Physical Medicine」の臨床的有用性とその科学的エビデンス

    • Author(s)
      甲斐 広文
    • Organizer
      第22回クリニカルファーマシーシンポジウム医療薬学フォーラム2014
    • Place of Presentation
      ビックサイトTFTホール(東京都江東区)
    • Year and Date
      2014-06-28 – 2014-06-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] Podocyte-specific p53 Deletion Promotes Alport Syndrome Progression by Enhancement of Podocyte Proliferation and Migration

    • Author(s)
      R. Fukuda, Y. Kai, K. Omachi, K. Motomura, T. Koga, K. Koyama, M. A. Suico, T. Shuto, H. Kai
    • Organizer
      Pharmacology 2014
    • Place of Presentation
      London(UK)
    • Year and Date
      2014-12-16 – 2014-12-18
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] 腎疾患におけるp53の病態生理学的役割と新たな病態進行抑制薬の開発に向けて

    • Author(s)
      甲斐 広文, 福田 亮介, 大町 紘平, スイコ メリアン, 首藤 剛
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] Physical medicineの科学的エビデンス構築と有効な疾患モデル

    • Author(s)
      甲斐 広文
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-03-18 – 2015-03-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] 単球系細胞における新規抗炎症分子FAM105Aの同定及び機能解析

    • Author(s)
      福田 亮介, 横田 翼, 古賀 友昭, 小山 皓介, Mary Ann Suico, 首藤 剛, 甲斐 広文
    • Organizer
      第31回日本薬学会九州支部大会
    • Place of Presentation
      第一薬科大学(福岡県福岡市)
    • Year and Date
      2014-12-06 – 2014-12-07
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] The effect of Mild Electrical Stimulation with Heat Shock on kidney dysfunction in type 2 diabetic KKAy mice.

    • Author(s)
      Y. Kai, R. Fukuda, K. Omachi, Y. Okamoto, M. Suico, T. Shuto, H. Kai
    • Organizer
      The 2014 ascb/ifcb Meeting
    • Place of Presentation
      Philadelphia(USA)
    • Year and Date
      2014-12-06 – 2014-12-10
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] 機能未知遺伝子FAM105Aの新規抗炎症制御分子としての可能性追求

    • Author(s)
      福田 亮介, 横田 翼, Mary Ann Suico, 首藤 剛, 古賀 友昭, 小山 皓介 , 甲斐 広文
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] Alport症候群の原因タンパク質COL4A5に注目した病態発症メカニズムの解明

    • Author(s)
      大町 紘平, 嘉村 美里, 寺本 啓祐, 福田 亮介, Mary Ann Suico, 首藤 剛, 甲斐 広文
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] Chemical Medicine と Physical Medicine の併用療法の有用性

    • Author(s)
      甲斐 広文
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸学院大学(兵庫県神戸市)
    • Year and Date
      2015-03-25 – 2015-03-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670260
  • [Presentation] The endoplasmic reticulum-oriented drug development for familial amyloid polyneuropathy

    • Author(s)
      K. Chosa, R. Yamakawa, T. Sato, T. Yokoyama, M. Mizuguchi, M. Suico, T. Shuto, H. Kai
    • Organizer
      WCP2014 17th World Congress of Basic & Clinical Pharmacology
    • Place of Presentation
      Cape Town(South Africa)
    • Year and Date
      2014-07-13 – 2014-07-18
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] 小胞体品質管理機構を標的とした家族性アミロイドポリニューロパチー(FAP)の新規治療薬開発

    • Author(s)
      帖佐 圭佑, 高木 舜, 山川 瑠斐子, 脇田 有梨子, 寺西 ゆり子, 佐藤 卓史, 横山 武司, 水口 峰之, Mary Ann Suico , 首藤 剛, 甲斐 広文
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-25253012
  • [Presentation] Characterization of the Intracellular Behavior of COL4A5 and Clarification of Molecular Mechanism of Alport Syndrome.

    • Author(s)
      K. Omachi, M. Kamura, K. Teramoto, R. Fukuda, M. Suico, T. Shuto, H. Kai
    • Organizer
      The 2014 ascb/ifcb Meeting
    • Place of Presentation
      Philadelphia(USA)
    • Year and Date
      2014-12-06 – 2014-12-10
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] 遺伝性腎疾患の発症機構に関わる新たな分子標的

    • Author(s)
      Mary Ann Suico, 福田 亮介, 首藤 剛, 甲斐 広文
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-03-18 – 2015-03-20
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] Podocyte-p53 is essential to control the progression of hereditary renal disease Alport syndrome

    • Author(s)
      H. Kai
    • Organizer
      「修飾シグナル病」第2回国際シンポジウム
    • Place of Presentation
      東京大学医科学研究所(東京都港区)
    • Year and Date
      2015-01-23 – 2015-01-24
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] Podocyte-specific p53 Deletion Promotes Alport Syndrome Progression by Enhancement of Podocyte Proliferation and Migration

    • Author(s)
      R. Fukuda, Y. Kai, K. Omachi, K. Motomura, T. Koga, K. Koyama, M. A. Suico, T. Shuto, H. Kai
    • Organizer
      The ASN Kidney Week 2014 Annual Meeting
    • Place of Presentation
      Philadelphia(USA)
    • Year and Date
      2014-11-13 – 2014-11-16
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] Alport症候群の原因タンパク質COL4A5に注目した病態発症メカニズムの解明

    • Author(s)
      大町 紘平, 嘉村 美里, 寺本 啓祐, 福田 亮介, Mary Ann Suico, 首藤 剛, 甲斐 広文
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PUBLICLY-25117721
  • [Presentation] バーチャルおよびハイスループットスクリーニングを用いた家族性アミロイドポリニューロパチーの新規治療薬の開発

    • Author(s)
      帖佐 圭佑, 高木 舜, 脇田 有梨子, 寺西 ゆり子, 山川 瑠斐子, 佐藤 卓史, 横山 武司, 水口 峰之, Mary Ann Suico , 首藤 剛, 甲斐 広文
    • Organizer
      第8回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      熊本大学薬学部(熊本県熊本市)
    • Year and Date
      2014-11-15 – 2014-11-16
    • Data Source
      KAKENHI-PROJECT-25253012
  • 1.  MIYATA Takeshi (90040310)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 1 results
  • 2.  SHUTO Ysuyoshi (80333524)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 119 results
  • 3.  TAKAHAMA Kazuo (80150548)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 4.  SUICO MARY Ann Soten (20363525)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  ARIMA Hidetoshi (50260964)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  ISOHAMA Yoichiro (10240920)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  NAKAYAMA Hitoshi (70088863)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  KUNIYASU Akihiko (90241348)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  HIRAYAMA Fumitoshi (90094036)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  UEKAMA Kaneto (90040328)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  OTAGIRI Masaki (80120145)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  TANASE Sumio (20112401)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  IKEMIZU Shinji (60333522)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 14.  TOKUTOMI Naofumi (30227582)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  沢登 徹 (00014217)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  ISHIZUKA Tadao (60176203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MIYAMOTO Eishichi (50109659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  FUKUNAGA Kohji (90136721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  YAMADA Gen (80174712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ANDO Yukio (20253742)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  YAMASHITA Taro (90381003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TANIHARA Hidenobu (60217148)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  庄司 省三 (60040317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  寺崎 久泰 (50381009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  塚本 佐知子 (40192190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  人羅 勇気 (00755308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  古賀 友紹 (30615092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  斉藤 貴志 (90360552)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KOTANI Shunsuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  SHIRAKI Nobuaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  KADOWAKI Hisae
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  UEDA Mitsuharu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  メリー・アン スイコ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 110 results
  • 34.  高里 実
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  庄野 朱美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  礒浜 洋一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  西頭 英起
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  水口 峰之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  荒木 栄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 40.  近藤 龍也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 41.  新井 祐志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  岸田 綱郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  金子 雅幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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