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UEMURA KOICHI  上村 公一

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UEMURA Koichi  上村 公一

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Researcher Number 30244586
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2015 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 教授
2015: 東京医科歯科大学, 医歯薬総合研究科(系)研究科, 教授
2012 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 教授
2010 – 2012: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授
2007 – 2010: Tokyo Medical and Dental University, Public health Graduate School, Professor … More
2007 – 2008: Tokyo Medical and Dental University, Graduate School, Professor
2007: 東京大学, 大学院・医学系研究科, 講師
2006: 東京大学, 大学院医学系研究科, 講師
2005: The University of Tokyo, Graduate School of Medicine, Lector, 大学院・医学系研究科, 講師
2002 – 2004: 東京大学, 大学院・医学系研究科, 助手
2000: University of Tokyo, Graduate School of Research Medicine, Associate, 大学院・医学系研究科, 助手
1999: 山口大学, 医学部, 助手
1994 – 1997: 京都府立医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Legal medicine / Legal medicine / Basic Section 58040:Forensics medicine-related
Except Principal Investigator
Legal medicine / Legal medicine / Basic Section 58040:Forensics medicine-related / Basic Section 58080:Gerontological nursing and community health nursing-related / Medium-sized Section 58:Society medicine, nursing, and related fields
Keywords
Principal Investigator
アポトーシス / apoptosis / H9c2 / ネクローシス / 細胞死 / ヒ素 / ラット / calcium / necrosis / reactive oxygen species … More / carbon monoxide / 活性酸素種 / HO-1 / カルシウム / 虚血 / 一酸化炭素 / methamphetamine / PC12 / 亜ヒ酸 / 心筋 / 心筋由来細胞 / アルコール嗜好性 / コカイン / 神経細胞死 / パイロトーシス / 細胞老化 / 酸化ストレス / ヒト肝がん細胞Huh-7 / ストレス顆粒 / フェロトーシス / ネクロトーシス / 神経細胞 / プロテアソーム / オートファジー / 三酸化二ヒ素 / ATR-Chk経路 / PML / 脳 / mitochondria / sepsis / rat / heart failure / hem-oxygenase-1 / mRNA / 蛋白量 / ヘミン / 培養細胞 / ミトコンドリア / 敗血症 / 心不全 / ヘムオキシゲナーゼ / L-type Ca^<2+> channel / ischemia / L-type Ca^<2+>チャンネル / ischemisa / 虚血細胞死 / 虚血細 / 活性酸素 / protein kinase C / cell death / glutamate receptor / Protein kinase C / 覚醒剤 / PKC / メタンフェタミン / プロテインキナーゼC / Alcohol metabolism / Monoamine / Mouse / Cocaine / Alcohol preference / アルコール代謝 / モノアミン / マウス / ubiquitin-proteasome系 / ユビキチン-プロテアソーム系 / Parkin / ユビキチンプロテアソーム系 / ユビキチン-プロテアソーム系 / 心筋細胞 / 肺胞上皮 / 肺胞上皮由来細胞 / 硫化水素 / ALDH / ADH / アルコール … More
Except Principal Investigator
メタボロミクス / 細胞毒性 / 虚血再灌流 / アルコール / メタボローム解析 / Nitorotyrosine (NT) / 4-Hydroxynonenal (HNE) / 過酸化脂質 / 活性酸素 / 虚血性心疾患 / 一酸化窒素 / アポトーシス / 細胞死 / コカイン / ミトコンドリア / オートファジー / プロテオミクス / 心筋梗塞 / 心理ストレス / 心筋虚血 / 不整脈 / コネクシン43 / 法医学 / 報償系 / 脳報償系 / セロトニン / ドパミン / 高齢者虐待 / ピンク歯 / 細胞老化 / メタボローム / Connexin 43 / Myocardial ischemia / hypertension / Psychological stress / Oxidative stress / Life-style diseases / 糖尿病 / シグナル伝達 / ストレス / 循環器・高血圧 / Nitorotyrosine(NT) / 4-Hydroxynonenal / 高血圧 / 酸化ストレス / 生活習慣病 / Inflammation / Metabolic syndrome / Myocardial cell death / Lipid peroxidation / Blood plow / Reactive oxygen species / Nitric oxide / Ishemia reperfusion / コネクシン / 炎症 / メタボリック症候群 / 心筋細胞死 / 血流 / Myocardial infarction / Cardiogenic pulmonary edema / Surfactant / サイトカイン / 心不全性肺水腫 / サーファクタント / Species Calcium / Reactive Oxygen / NO syntase / Reperfusion / Ischemia / Myocardium / Nitric Oxide / Carbon Monoxide / 細胞内情報伝達 / 血管内皮 / 心臓 / 脂質過酸化 / 遅発脳障害 / 一酸化炭素(CO) / カルシウム / 活性酵素種 / NO合成酵素 / 再灌流 / 虚血 / 心筋 / 一酸化炭素 / Dying process / Deep electroencephalogram / Triazolam / 薬物相互作用 / 血中濃度 / エタノール / 致死過程 / 深部脳波 / トリアゾラム / 心筋障害 / 肺線維症 / 中毒学 / パラコート / 薬毒物 / トランスクリプトミクス / PAG / 免疫組織化学 / 視床下部外側野 / アルコール行動 / 習慣飲酒 / 扁桃体 / 視床下部 / グレリン受容体 / グレリン / 細胞障害 / マクロピノサイトース / 覚せい剤 / プロテオーム / 心理的ストレス / 心臓性突然死 / 心筋収縮帯 / 身体拘束 / 心臓突然死 / ギャップ結合 / 解剖 / データベース / 死因 / 薬物分析 / マトリックス効果 / カルボン酸 / ガスクロマトグラフィー / 神経毒 / 依存 / 受容体 / 扁桃核 / 側座核 / 薬物依存 Less
  • Research Projects

    (27 results)
  • Research Products

    (109 results)
  • Co-Researchers

    (31 People)
  •  メタボローム解析を用いた細胞老化を伴う毒性機序の解析と新規細胞老化マーカーの探索

    • Principal Investigator
      船越 丈司
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Tokyo Medical and Dental University
  •  ピンク歯現象の発色および退色機序に関する検討

    • Principal Investigator
      櫻田 宏一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  高齢者の身体的虐待の特徴と傾向に基づく関連機関の連携に関する研究

    • Principal Investigator
      櫻田 宏一
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58080:Gerontological nursing and community health nursing-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Neuronal death induced by arsenic --- Participation of necroptosis and ferroptosisPrincipal Investigator

    • Principal Investigator
      UEMURA KOICHI
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Construction of a method for analyzing the toxic mechanism and new toxic markers by metabolome analysis

    • Principal Investigator
      Funakoshi Takeshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Cell death induced by arsenite in relation to autophasy and proteasome systemPrincipal Investigator

    • Principal Investigator
      UEMURA Koichi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of drug toxicity mechanism and toxicity evaluation method using targeted metabolome method

    • Principal Investigator
      Funakoshi Takeshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular analysis of drug intoxication by use of integrated toxicomics

    • Principal Investigator
      Aki Toshihiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular biochemical studies on the mechanisms of arsenite-induced intoxicationPrincipal Investigator

    • Principal Investigator
      Uemura koichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Habitual alcohol-drinking behavior associated with active ghrelinergic and serotonergic neurons in the lateral hypothalamus and amygdala

    • Principal Investigator
      Yoshimoto Kanji
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      Hiroshima Institute of Technology
      Kyoto Prefectural University of Medicine
  •  Proteomic screening of possible marker proteins for drug-induced cellular injuries

    • Principal Investigator
      AKI Toshihiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Studies on the mechanisms of cell toxicity caused by hydrogen sulfidePrincipal Investigator

    • Principal Investigator
      UEMURA Kouichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Research on the molecular mechanism underlying sudden cardiac deaths due to toxic substanses, ischemia and emotional stress

    • Principal Investigator
      YOSHIDA Ken-ichi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  The study of the method for improving sensitivity of gaschromatography by carboxylic acid addition

    • Principal Investigator
      SAKA Kanju
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  法医学解剖情報のデータベース化による事故・犯罪予防システムの構築

    • Principal Investigator
      木内 貴弘
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  Research on the contribution of oxidative stress to the pathogenesis of cardiovascular diseases associated with life-styles

    • Principal Investigator
      YOSHIDA Ken-ichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  Studies on the involvement of carbon monoxide and hem-oxygenase (HO)-1 in the pathophysiology of the heart failurePrincipal Investigator

    • Principal Investigator
      UEMURA Koichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Tokyo Medical and Dental University
      The University of Tokyo
  •  Molecular pathological study on vascular lesions due to ischemic heart diseases and related diseases

    • Principal Investigator
      YOSHIDA Ken-ich
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  Studies on the molecular and protective mechanisms of carbon monoxide on the ischemia, intoxication and infection.Principal Investigator

    • Principal Investigator
      UEMURA Koichi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  Study of the molecular alteration of surfactant on inflammable lung diseases for an application to the forensic medicine

    • Principal Investigator
      SHINTANI Kaori
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  Research on cell injury due to Carbon Monoxide and Nitric Oxide under ischemia or shock

    • Principal Investigator
      YOSHIDA Ken-ichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  Studies on the molecular mechanisms of carbon monoxide on the induction or protection of cell death.Principal Investigator

    • Principal Investigator
      UEMURA Koichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      The University of Tokyo
  •  Studies on the intra-cellular response to the stress under the process of neuronal degeneration induced by methamphetamine.Principal Investigator

    • Principal Investigator
      UEMURA Koichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      University of Tokyo
      Yamaguchi University
  •  Neurochemical studies on the interaction cocaine and alcoholPrincipal Investigator

    • Principal Investigator
      UEMURA Koichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  脳報償系機能からみたアルコール依存形成機序の法医中毒学的基礎研究

    • Principal Investigator
      Yoshimoto Kanji (吉本 寛治)
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  コカインとその代謝物の定量とコカインとアルコールの相互作用についてPrincipal Investigator

    • Principal Investigator
      上村 公一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Legal medicine
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Forensic study on death of triazolam intoxication

    • Principal Investigator
      KOMURA Setsuo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Aristolochic acid induces an inflammatory response with prostaglandin E2 production and apoptosis in NRK-52E proximal tubular cells2023

    • Author(s)
      Komatsu M, Funakoshi T, Aki T, Unuma K, Uemura K.
    • Journal Title

      Toxicology letters

      Volume: 378 Pages: 39-50

    • DOI

      10.1016/j.toxlet.2023.02.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K10605, KAKENHI-PROJECT-20H03955, KAKENHI-PROJECT-23K09760
  • [Journal Article] Effects on oral tissues of asphyxiation caused by cervical compression: The pink teeth phenomenon in Kato's studies (1941)2023

    • Author(s)
      Koichi Sakurada
    • Journal Title

      Legal Medicine

      Volume: 64 Pages: 102284-102284

    • DOI

      10.1016/j.legalmed.2023.102284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K19644
  • [Journal Article] Study on the mechanism of the pink tooth phenomenon using bovine teeth:a pilot study2023

    • Author(s)
      Nozomi Sumi, Saki Minegishi, Jun Ohta, Hajime Utsuno, Koichi Sakurada
    • Journal Title

      diagnostics

      Volume: 13 Issue: 16 Pages: 2699-2699

    • DOI

      10.3390/diagnostics13162699

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19644
  • [Journal Article] Forensic Characteristics of Physical Elder Abuse and Current Status and Issues of Collaboration between Forensic Medicine Departments and Related Institutions in Japan2022

    • Author(s)
      Toya Maiko、Minegishi Saki、Utsuno Hajime、Ohta Jun、Namiki Shuuji、Unuma Kana、Uemura Koichi、Sakurada Koichi
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 19 Issue: 22 Pages: 15382-15382

    • DOI

      10.3390/ijerph192215382

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24669
  • [Journal Article] Oxcarbazepine induces mitotic catastrophe and apoptosis in NRK-52E proximal tubular cells2021

    • Author(s)
      Ota Momoka、Funakoshi Takeshi、Aki Toshihiko、Unuma Kana、Uemura Koichi
    • Journal Title

      Toxicology Letters

      Volume: 350 Pages: 240-248

    • DOI

      10.1016/j.toxlet.2021.07.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K10680, KAKENHI-PROJECT-19K10682
  • [Journal Article] Repeated exposure of cocaine alters mitochondrial dynamics in mouse neuroblastoma Neuro2a2019

    • Author(s)
      Funakoshi Takeshi、Furukawa Mako、Aki Toshihiko、Uemura Koichi
    • Journal Title

      NeuroToxicology

      Volume: 75 Pages: 70-77

    • DOI

      10.1016/j.neuro.2019.09.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K10682, KAKENHI-PROJECT-18K19670
  • [Journal Article] Ataxia telangiectasia and rad3 related (ATR)-promyelocytic leukemia protein (PML) pathway of the DNA damage response in the brain of rats administered arsenic trioxide2017

    • Author(s)
      Ryo Watanabe, Kana Unuma, Kanako Noritake, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura.
    • Journal Title

      Journal of Toxicologic Pathology

      Volume: 30 Issue: 4 Pages: 333-337

    • DOI

      10.1293/tox.2017-0020

    • NAID

      130006176567

    • ISSN
      0914-9198, 1881-915X
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09201, KAKENHI-PROJECT-16K09203
  • [Journal Article] Lipopolysaccharide induces expression of collagen VI in the rat lung2015

    • Author(s)
      Okawa S, Unuma K, Yamada A, Aki T, Uemura K
    • Journal Title

      J Toxicol Pathol.

      Volume: 28(1) Issue: 1 Pages: 37-41

    • DOI

      10.1293/tox.2014-0053

    • NAID

      130004842606

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-26713024
  • [Journal Article] Regulated necrosis and its implications in toxicology2015

    • Author(s)
      Aki T, Funakoshi T, Uemura K
    • Journal Title

      Toxicology

      Volume: 333 Pages: 118-126

    • DOI

      10.1016/j.tox.2015.04.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Journal Article] Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes.2015

    • Author(s)
      Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K.
    • Journal Title

      PLoS One

      Volume: 10(8) Issue: 8 Pages: e0136952-e0136952

    • DOI

      10.1371/journal.pone.0136952

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H06182, KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-26713024
  • [Journal Article] Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy.2015

    • Author(s)
      Unuma K, Aki T, Funakoshi T, Hashimoto K, Uemura K
    • Journal Title

      Autophagy

      Volume: 11(9) Issue: 9 Pages: 1520-1536

    • DOI

      10.1080/15548627.2015.1063765

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Journal Article] Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells.2015

    • Author(s)
      5.Atsushi Yamada, Toshihiko Aki, Kana Unuma, Takeshi Funakoshi, Koichi Uemura
    • Journal Title

      PLOSONE

      Volume: 10(3) Issue: 3 Pages: e0120192-e0120192

    • DOI

      10.1371/journal.pone.0120192

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Journal Article] Activation of Master Autophagy Regulator TFEB During Systemic LPS Administration in the Cornea2014

    • Author(s)
      8.Kyoko Uchida, Kana Unuma, Takeshi Funakoshi, Toshihiko Aki, and Koichi Uemura
    • Journal Title

      Journal of Toxicologic Pathology

      Volume: 27 Issue: 2 Pages: 153-158

    • DOI

      10.1293/tox.2014-0004

    • NAID

      130003391349

    • ISSN
      0914-9198, 1881-915X
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-26713024
  • [Journal Article] Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis.2014

    • Author(s)
      Mayumi Watanabe, Takeshi Funakoshi, Kana Unuma, Toshihiko Aki#, and Koichi Uemura
    • Journal Title

      Toxicology

      Volume: 322 Pages: 43-50

    • DOI

      10.1016/j.tox.2014.04.008

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-25460863, KAKENHI-PROJECT-26713024
  • [Journal Article] Rho-kinase inhibitor Y-27632 attenuates arsenic trioxide toxicity on H9c2 cardiomyoblastoma cells2013

    • Author(s)
      Marie Bessho, Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Kanako Noritake, Chizuru Kato, and Koichi Uemura
    • Journal Title

      Cardiovasc.Toxicol

      Volume: (印刷中)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/23532581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Journal Article] Impairment of autophagy: from hereditary disorder to drug intoxication (Review).2013

    • Author(s)
      Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, and Koichi Uemura
    • Journal Title

      Toxicology

      Volume: 311 Issue: 3 Pages: 205-215

    • DOI

      10.1016/j.tox.2013.07.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Journal Article] Inducer of heme oxygenase-1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during LPS treatment inrat liver2013

    • Author(s)
      Kana Unuma, Toshihiko Aki, Seiji Matsuda, Takeshi Funakoshi, Ken-ichi Yoshida, Koichi Uemura
    • Journal Title

      Hepatology Res

      Volume: 43 Issue: 1 Pages: 91-96

    • DOI

      10.1111/j.1872-034x.2012.01049.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629, KAKENHI-PROJECT-22591637, KAKENHI-PROJECT-24790639
  • [Journal Article] Elimination and active extrusion of livermitochondrial proteins during LPS administration in rat2013

    • Author(s)
      Kana Unuma, Toshihiko Aki, Seiji Matsuda, Takeshi Funakoshi, Ken-ichi Yoshida, Koichi Uemura
    • Journal Title

      Hepatology Res

      Volume: 43 Issue: 5 Pages: 526-534

    • DOI

      10.1111/j.1872-034x.2012.01084.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629, KAKENHI-PROJECT-22591637, KAKENHI-PROJECT-24790639
  • [Journal Article] Acetaldehyde-induced cytotoxicity involves induction of spermin oxidase at the tanscriptional level.2013

    • Author(s)
      Uemura M, Tanaka Y, Higashi K, Miyamori D, Takasaka T, Nagano T, Toida T, Yoshimoto K, Igarashi K and Ikegaya H
    • Journal Title

      Toxicology

      Volume: 310 Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390176
  • [Journal Article] Lysosome vacuolation disrupts the completion of autophagy during norephedrine exposure in SH-SY5Y human neuroblastoma cells2013

    • Author(s)
      Takeshi Funakoshi, Toshihiko Aki, Kana Unuma, Koichi Uemura
    • Journal Title

      Brain Res

      Volume: 1490 Pages: 9-22

    • DOI

      10.1016/j.brainres.2012.10.056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629, KAKENHI-PROJECT-24790639, KAKENHI-PROJECT-25860487
  • [Journal Article] Cobalt protoporphyrin accelerates TFEBactivation and lysosome reformation during LPS-induced septic insults in rat heart2013

    • Author(s)
      Kana Unuma, Toshihiko Aki, Seiji Matsuda, Takeshi Funakoshi, Ken-ichi Yoshida, Koichi Uemura
    • Journal Title

      PLOS ONE

      Volume: e59526 Issue: 2 Pages: 8-8

    • DOI

      10.1371/journal.pone.0056526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629, KAKENHI-PROJECT-23249038
  • [Journal Article] Distinct effects of methamphetamine on autophagy-lysosome and ubiquitin-proteasome systems in HL-1 cultured mouse atrial cardiomyocytes.2013

    • Author(s)
      Funakoshi-Hirose I, Aki T, Unuma K, Funakoshi T, Noritake K, Uemura K.
    • Journal Title

      Toxicology.

      Volume: 312(4) Pages: 74-82

    • DOI

      10.1016/j.tox.2013.07.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790639, KAKENHI-PROJECT-25460862
  • [Journal Article] Hyperstimulation of macropinocytosis leads to lysosomal dysfunction and cell death during exposure to methamphetamine in differentiatedSH-SY5Y cells2012

    • Author(s)
      Akina Nara, Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Koichi Uemura
    • Journal Title

      Brain Res

      Volume: 1466 Pages: 1-14

    • DOI

      10.1016/j.brainres.2012.05.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Journal Article] Cytoplasmic vacuolization during exposure to drugs and other substances (Review)2012

    • Author(s)
      Toshihiko Aki, Akina Nara, and Koichi Uemura
    • Journal Title

      Cell Biol. and Toxicol

      Volume: 28 Pages: 125-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Journal Article] Critical roles of Rho-associated kinase in membrane blebbing and mitochondrial apoptosis caused by 1-butanol2012

    • Author(s)
      Kanako Noritake, Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Akina Nara, Chizuru Kato, and Koichi Uemura
    • Journal Title

      Toxicol. inVitro

      Volume: 26 Issue: 6 Pages: 849-855

    • DOI

      10.1016/j.tiv.2012.04.027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Journal Article] Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway bychelerythrine2011

    • Author(s)
      Takeshi Funakoshi, Toshihiko Aki, HarukaNakayama, Yumi Watanuki, Satoko Imori,and Koichi Uemura
    • Journal Title

      Toxicol. in Vitro

      Volume: 25 Issue: 8 Pages: 1581-1587

    • DOI

      10.1016/j.tiv.2011.05.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Journal Article] Brief exposure to carbon monoxide preconditions cardiomyogenic cells against apoptosis in ischemia-reperfusion.2010

    • Author(s)
      Kondo-Nakamura M, Shintani-Ishida K, Uemura K, Yoshida K.
    • Journal Title

      Biochem Biophys Res Commun. 393(3)

      Pages: 4494-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390193
  • [Journal Article] Bifurcate effects of glucose on caspase-independent cell death during hypoxia2010

    • Author(s)
      Toshihiko Aki, Akina Nara, Takeshi Funakoshi, Koichi Uemura
    • Journal Title

      Biochem.Biophys. Res. Commun

      Volume: 396 Issue: 3 Pages: 614-618

    • DOI

      10.1016/j.bbrc.2010.04.122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Journal Article] Brief exposure to carbon monoxide preconditions cardiomyogenic cells against apoptosis in ischemia-reperfusion.2010

    • Author(s)
      Kondo-Nakamura M, Shintani-Ishida K, Uemura K, Yoshida K.
    • Journal Title

      Biochemistry Biophysics Research Communication

      Volume: 393(3) Pages: 449-454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390193
  • [Journal Article] Methamphetamine induces macropinocytosis in differentiatedSH-SY5Y human neuroblastoma cells2010

    • Author(s)
      Akina Nara, Toshihiko Aki, Takeshi Funakoshi, Koichi Uemura
    • Journal Title

      Brain Res

      Volume: 1352 Pages: 1-10

    • DOI

      10.1016/j.brainres.2010.07.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Journal Article] Determination of amobarbital and phenobarbital in serum by gas chroma tography-mass spectrometry with addition of formic acid to the solvent2008

    • Author(s)
      Saka K, Uemura K, Shintani-Ishida K, Yoshida K
    • Journal Title

      J Chromatogr B. 869

      Pages: 9-15

    • NAID

      10028001848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390193
  • [Journal Article] A death due to perirenal hematoma complicating extracorporeal shockwave lithotripsy.2008

    • Author(s)
      Uemura K, Takahashi S, Shintani-shida K, Nakajima M, Saka K, Yoshida K
    • Journal Title

      J Forensic Sci. 53

      Pages: 469-471

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390193
  • [Journal Article] A new method for ABO genotyping to avoid discrepancy between genetic and serological determinations2008

    • Author(s)
      Shintani-Ishida K, Zhu BL, Maeda H, Uemura K, Yoshida K
    • Journal Title

      Int J Legal med 122(1)

      Pages: 7-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] An autopsy report on four sudden cardiac death cases by Immobilization.2008

    • Author(s)
      Uemura K, Ueyama T, Shintani-Ishida K, Unuma K, Yoshida K.
    • Journal Title

      International Medical Journal 15

      Pages: 301-305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390193
  • [Journal Article] Biochemical blood markers and sampling sites in forensic autopsy.2008

    • Author(s)
      Uemura K, Shintani-Ishida K, Saka K, Nakajima M, Ikegaya H, Kikuchi Y, Yoshida K
    • Journal Title

      J Forensic Leg Med 15

      Pages: 312-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390193
  • [Journal Article] A death due to perirenal hematoma complicating extracorporeal shockwave lithotripsy.2008

    • Author(s)
      Uemura K, Takahashi S, Shintani-Ishida K, Nakajima M, Saka K, Yoshida K
    • Journal Title

      J. Forensic Sci 53(2)

      Pages: 469-471

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] A death due to perirenal hematoma complicating extracorporeal shockwave lithotripsy2008

    • Author(s)
      Uemura K, Takahashi S, Shintani-Ishida K, Nakajima M, Saka K, Yoshida K
    • Journal Title

      J Forensic Sci 53(2)

      Pages: 469-471

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] An autopsy report on four sudden cardiac death cases by Immobilization.2008

    • Author(s)
      Uemura K, Ueyama T, Shintani-Ishida K, Unuma K, Yoshida K
    • Journal Title

      Int Med J. 15

      Pages: 301-305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390193
  • [Journal Article] A new method for ABO genotyping to avoid discrepancy between genetic and ser ological determinations2008

    • Author(s)
      Shintani-Ishida K, Zhu BL, Maeda H, Uemura K, Yoshida K
    • Journal Title

      Int J Legal med 122(1)

      Pages: 7-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] A new method for ABO genotyping to avoid discrepancy between genetic and serological determinations.2008

    • Author(s)
      Shintani-Ishida K, Zhu BL, Maeda H, Uemura K, Yoshida K
    • Journal Title

      Int J. Legal med. 122(1)

      Pages: 7-9

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] Determination of amobarbitaland phenobarbital in serum by gaschromatography-mass spectrometry withaddition of formic acid to the solvent2008

    • Author(s)
      Saka K, Uemura K, Shintani-Ishida K, Yoshida K.
    • Journal Title

      J Chromatogr B. 869

      Pages: 9-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590669
  • [Journal Article] A new method for ABO genotyping to avoid discrepancy between genetic and serological determinations.2008

    • Author(s)
      Shintani-Ishida K, Zhu BL, Maeda H, Uemura K, Yoshida K
    • Journal Title

      Int J Legal Med 122

      Pages: 7-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390193
  • [Journal Article] A death due to perirenal hematoma complicating extracorporealripsy2008

    • Author(s)
      Uemura K, Takahashi S, Shintani-Ishida K, Nakajima M, Saka K, Yoshida K
    • Journal Title

      J Forensic Sci 53(2)

      Pages: 469-471

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] Acetic acid improves thesensitivity of theophylline analysis by gaschromatography-mass spectrometry2007

    • Author(s)
      Saka K, Uemura K, Shintani-Ishida K, Yoshida K.
    • Journal Title

      J Chromatogr B. 846

      Pages: 240-244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590669
  • [Journal Article] Hemichannels in cardiomyocytes open transiently during ischemia and contribute to reperfusion injury following brief ischemia2007

    • Author(s)
      Shintani-Ishida K, Uemura K, Yoshida K
    • Journal Title

      Am J. Physiol Heart Circ Physiol. 293

      Pages: 1714-1720

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] Ischemic preconditioning protects cardiomyocytes against ischemic injury by inducing GRP78.2006

    • Author(s)
      Shintani-lshida K, Nakajima M, Uemura K, Yoshida K.
    • Journal Title

      Biochem Biophys Res Commun. 345(4)

      Pages: 1600-1605

    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] Ischemic preconditioning protects cardiomyocytes against ischemic injury by inducing GRP78.2006

    • Author(s)
      Shintani-Ishida K, Nakajima M, Uemura K, Yoshida K.
    • Journal Title

      Biochem Biophys Res Commun. 345(4)

      Pages: 1600-1605

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] Ischemic preconditioning protects cardiomyocytes against ischemic injury by inducing GRP782006

    • Author(s)
      Shintani-Ishida K, Nakajima M, Uemura K, Yoshida K.
    • Journal Title

      Biochem Biophys Res Commun 345(4)

      Pages: 1600-1605

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Journal Article] NO synthase (eNOS) phosphorylation regulates coronary diameter during ischemia-reperfusion in association with oxidative stress.2005

    • Author(s)
      Hoshino S, Kikuchi Y, Uemura K, Yoshida K. et al.
    • Journal Title

      Free Radic Res. 39

      Pages: 481-489

    • Data Source
      KAKENHI-PROJECT-16390191
  • [Journal Article] Carbon monoxide protects cardiomyogenic cells against ischemic death through L-type Ca^<2+> channel inhibition.2005

    • Author(s)
      Koichi Uemura, Satomi Adachi-Akahane, Kaori Shintani-Ishida, Ken-ichi Yoshida
    • Journal Title

      Biochemical and Biophysical Research Communications 334

      Pages: 661-668

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590534
  • [Journal Article] A possible site of superoxide generation in the complex I segment of rat heart mitochondria.2005

    • Author(s)
      Ohnishi ST, Ohnishi T, Uemura K, Yoshida K et al.
    • Journal Title

      J Bioenerg Biomembr. 37

      Pages: 1-15

    • Data Source
      KAKENHI-PROJECT-16390191
  • [Journal Article] Carbon monoxide protects cardiomyogenic cells against ischemic death through L-type Ca2+ channel inhibition.2005

    • Author(s)
      Uemura K, Adachi-Akahane S, Shintani-Ishida K, Yoshida K.
    • Journal Title

      Biochem Biophys Res Commun. 334

      Pages: 661-668

    • Data Source
      KAKENHI-PROJECT-16390191
  • [Journal Article] Carbon monoxide protects cardiomyogenic cells against ischemic death through L-type Ca2+ channel inhibition.2005

    • Author(s)
      Uemura K, Adachi-Akahane S, Shintani-Ishida K, Yoshida K.
    • Journal Title

      Biochem Biophys Res Commum 344(2)

      Pages: 661-668

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390191
  • [Journal Article] Carbon monoxide protects cardiomyogenic cells against ischemic death through L-type Ca^<2+> channel inhibition.2005

    • Author(s)
      Koichi Uemura, Satomi Adachi-Akahane, Kaori Shintani-Ishida, Ken-ichi Yoshida.
    • Journal Title

      Biochemical and Biophysical Research Communications 334

      Pages: 661-668

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590534
  • [Journal Article] Carbon monoxide protects cardiomyogenic cells against is chemic death through L-type Ca2+ channel inhibition.2004

    • Author(s)
      Uemura K, Yoshida K et al.
    • Journal Title

      Biochem Biophys Res Commum. 334・2

      Pages: 661-668

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390191
  • [Journal Article] Sudden death of a patient with primary hypereosinophilia, colon tumours, and pulmonary emboli.2004

    • Author(s)
      Uemura K, Yoshida K et al.
    • Journal Title

      J Clin Pathol. 57(5)

      Pages: 541-543

    • Data Source
      KAKENHI-PROJECT-16390191
  • [Journal Article] Hemichannels in cardiomyocytes open transiently during ischemia and contribute to reperfusion injury following brief ischemia

    • Author(s)
      Shintani-Ishida K, Uemura K, Yoshida K
    • Journal Title

      Am J Physiol Heart Circ Physiol 293

      Pages: 1714-1720

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Presentation] 通所介護事業所における高齢者の身体的虐待の外傷所見と関連機関との連携についての調査研究2023

    • Author(s)
      戸谷 麻衣子、峰岸 沙希、宇都野 創、大田 隼、 並木 修司、壽美 望、斉藤 久子、鵜沼 香奈、上村 公一、櫻田 宏一
    • Organizer
      第92回日本法医学会学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-23K24669
  • [Presentation] アリストロキア酸による近位尿細管急性毒性と DNA 損傷の検討2023

    • Author(s)
      小松美結, 船越丈司, 上村公一
    • Organizer
      第 46 回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K10605
  • [Presentation] 高齢者の身体的虐待の法医学的特徴と関連機関における連携に関する現状と課題2022

    • Author(s)
      戸谷麻衣子、峰岸沙希、宇都野創、大田隼、並木修司、 鵜沼香奈、上村公一、櫻田宏一
    • Organizer
      第18回日本高齢者虐待防止学会
    • Data Source
      KAKENHI-PROJECT-23K24669
  • [Presentation] 持続型硫化水素発生剤に対する細胞応答のA549ヒト肺胞上皮細胞モデルを用いた検討2021

    • Author(s)
      梶原美祐、秋利彦、加藤千鶴、船越丈司、青木奨、 鵜沼香奈、上村公一
    • Organizer
      第90回日本法医学会学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-19K10682
  • [Presentation] アリストロキア酸による近位尿細管細胞への細胞毒性の検討2021

    • Author(s)
      小松 美結 , 船越 丈司 , 秋 利彦 , 上村 公一
    • Organizer
      第105次日本法医学会全国集会
    • Data Source
      KAKENHI-PROJECT-19K10682
  • [Presentation] ヒ素の神経細胞特異的な毒性機序の解明2020

    • Author(s)
      溝部万純、秋利彦、船越丈司、平山菜穂、渡邊嶺、永井みどり、野村萌夏、上村公一
    • Organizer
      第89回日本法医学会学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-19K10682
  • [Presentation] ヒ素の神経細胞特異的な毒性機序の解明2020

    • Author(s)
      溝部万純、秋利彦、船越丈司、平山菜穂、渡邊嶺、永井みどり、野村萌夏、上村公一
    • Organizer
      日本法医学会第89回学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-19K10681
  • [Presentation] 抗てんかん薬オクスカルバゼピンの腎近位尿細管への影響2020

    • Author(s)
      太田百香、船越丈司、鵜沼香奈、則竹香菜子、佐野智美、村田達彦、上村公一
    • Organizer
      第89回日本法医学会学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-19K10682
  • [Presentation] コカイン長期曝露による神経細胞ミトコンドリアダイナミクスへの影響2019

    • Author(s)
      船越丈司、古川真子、秋利彦、上村公一
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K10682
  • [Presentation] 神経細胞におけるコカイン長期曝露の影響について2018

    • Author(s)
      古川真子, 秋利彦, 船越丈司, 鵜沼香奈, 平山菜穂, 渡邊嶺, 上村公一.
    • Organizer
      第87 回日本法医学会学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-16K09202
  • [Presentation] クロルプロマジン曝露におけるラットグリア細胞由来C6 細胞の細胞死について2018

    • Author(s)
      高橋蓮穂, 秋利彦, 船越丈司, 鵜沼香奈, 則竹香菜子, 永井みどり, 佐野智美, 上村公一
    • Organizer
      第87 回日本法医学会学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-16K09202
  • [Presentation] ラット脳組織における三酸化二ヒ素のPML及びDNA損傷チェックポイント機構への影響2018

    • Author(s)
      渡邊 嶺、鵜沼 香奈、秋 利彦、上村 公一
    • Organizer
      日本生化学会第91回大会
    • Data Source
      KAKENHI-PROJECT-16K09201
  • [Presentation] 覚せい剤原料ノルエフェドリン曝露による神経細胞内コレステロール異常蓄積とネクロトーシス誘導の解析2017

    • Author(s)
      船越丈司、秋利彦、鵜沼香奈、則竹香菜子、上村公一
    • Organizer
      第101回法医学会全国集会
    • Data Source
      KAKENHI-PROJECT-16K09202
  • [Presentation] ノルエフェドリンによる神経細胞内コレステロール蓄積とネクロトーシス誘導の解析2017

    • Author(s)
      船越丈司,秋利彦,鵜沼香奈,則竹香菜子,上村公一
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16K09202
  • [Presentation] メタボローム解析を用いた薬物毒性評価法の構築2017

    • Author(s)
      佐野智美、船越丈司、則竹香菜子、上村公一
    • Organizer
      第86回日本法医学会学術関東地方集会
    • Data Source
      KAKENHI-PROJECT-16K09202
  • [Presentation] 三酸化二ヒ素の中枢神経系におけるPML 及びDNA 損傷チェックポイント機構への影響.2016

    • Author(s)
      渡邊嶺, 鵜沼香奈, 秋利彦, 上村公一
    • Organizer
      第85 回日本法医学会学術関東地方集会
    • Place of Presentation
      横須賀
    • Data Source
      KAKENHI-PROJECT-16K09201
  • [Presentation] パラコートによる呼吸器上皮細胞の上皮間葉転換誘導後の線維化とその細胞保護的役割の検討2015

    • Author(s)
      山田真嗣,秋利彦,上村公一
    • Organizer
      第88回日本生化学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] 平滑筋細胞へのコカイン曝露によるMFG-E8の増加とその病態生理学的意義2015

    • Author(s)
      木村(小島)遥、鵜沼香奈、秋利彦、上村公一
    • Organizer
      第88回日本生化学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-02
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] HL-1心筋細胞においてエタノールは細胞間接着・細胞骨格を破綻し、Hippo経路の機能を障害する2015

    • Author(s)
      則竹香菜子、秋利彦、上村公一
    • Organizer
      第88回日本生化学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] アルコールの毒性と心筋細胞障害2015

    • Author(s)
      則竹香菜子、秋 利彦、上村公一
    • Organizer
      第50回日本アルコール・薬物医学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-10-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] Activation of ubiquitin-proteasome system plays a protective role in arsenic trioxide-induced cardiotoxicity2014

    • Author(s)
      Mayumi Watanabe, Takeshi Funakoshi, Kana Unuma, Toshihiko Aki, Koichi Uemura
    • Organizer
      9th International Symposium on Advances in Legal Medicine
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25460863
  • [Presentation] 抗精神病薬ハロペリドールによる コレステロール代謝変2014

    • Author(s)
      相原瑶、船越丈司、加藤千鶴、秋利彦、上村公一
    • Organizer
      第83回日本法医学会学術関東地方集会
    • Place of Presentation
      東京都新宿区東京女子医科大学
    • Year and Date
      2014-11-08
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] アルコールによる心筋細胞への影響2014

    • Author(s)
      則竹香菜子、秋 利彦、上村公一
    • Organizer
      第49回日本アルコール・薬物医学会
    • Place of Presentation
      神奈川県横浜市パシフィコ横浜
    • Year and Date
      2014-10-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] 覚せい剤原料ノルエフェドリン暴露による細胞内コレステロール変動の解析2013

    • Author(s)
      船越 丈司,秋利彦,鵜沼 香奈,上村 公一
    • Organizer
      第36回日本分子生物学会
    • Place of Presentation
      兵庫県神戸市神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] コカインによるアポトーシス誘導におけるオートファジー・リソソームの関与2013

    • Author(s)
      小島遥、則竹香菜子、藤井祐介、船越丈司、秋利彦、上村公一
    • Organizer
      第82回日本法医学会学術関東地方集会
    • Place of Presentation
      神奈川県横浜市はまぎんホール
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] 敗血症モデルラットの角膜におけるオートファジー誘導性転写因子TFEBの活性化2013

    • Author(s)
      内田恭子、鵜沼香奈、船越丈司、秋利彦、上村公一
    • Organizer
      第82回日本法医学会学術関東地方集会
    • Place of Presentation
      神奈川県横浜市はまぎんホール
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] 心筋ギャップ結合制御機構に及ぼすエタノールの影響2013

    • Author(s)
      則竹香菜子、秋利彦、上村公一
    • Organizer
      平成 25年度アルコール・薬物依存関連学会合同学術総会
    • Place of Presentation
      岡山県岡山市岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] エタノールが心筋ギャップ結合に及ぼす影響2013

    • Author(s)
      則竹香菜子、秋利彦、上村公一
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      神奈川県横浜市パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25460862
  • [Presentation] マウス心房由来心筋細胞HL-1におけるメタンフェタミンの毒性2012

    • Author(s)
      船越泉、鵜沼香奈、則竹香菜子、秋利彦、上村公一
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-16
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] 敗血症モデル動物の前房水、硝子体、水晶体における構成タンパク質の変動の検討2012

    • Author(s)
      内田恭子、鵜沼香奈、船越丈司,秋利彦、上村公一
    • Organizer
      第96回日本法医学会
    • Place of Presentation
      浜松
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] 覚せい剤原料ノルエフェドリンによる神経細胞毒性機序の検討2012

    • Author(s)
      船越丈司,秋利彦,鵜沼香奈,上村公一
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] 亜ヒ酸によるRhoキ ナーゼ依存的なアポトーシスの誘導2012

    • Author(s)
      別所麻里江、則竹香菜子、藤井祐介、 秋利彦、上村公一
    • Organizer
      第81回日本法医学会学術関東地方集会
    • Place of Presentation
      高崎
    • Year and Date
      2012-10-20
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] ラット肺上皮由来L2細胞における硫化水素の毒性の検討2012

    • Author(s)
      藤井祐介、船越丈司、秋利彦、上村公一
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-16
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] 筋芽細胞におけるコカインの細胞毒性2011

    • Author(s)
      綿貫裕美、秋利彦、則竹香菜子、船越丈司、上村公一
    • Organizer
      第80回日本法医学会学術関東地方集会
    • Place of Presentation
      宇都宮
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] Methamphetamine-caused cytotoxic effects involvesmacropinocytosis in differentiatedSH-SY5Y cells2011

    • Author(s)
      奈良明奈,秋利彦,船越丈司,鵜沼香奈,上村公一
    • Organizer
      第95回日本法医学会
    • Place of Presentation
      福島
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] Signaling pathway of macropinocytosis bymethamphetamine in human neuroblastoma cells2011

    • Author(s)
      Akina Nara, Toshihiko Aki, Takeshi Funakoshi, Kana Unuma and Koichi Uemura
    • Organizer
      6th International Symposium Advances in Legal Medicine
    • Place of Presentation
      ドイツ
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] Involvement of Rho-associated kinase in the cytotoxity of 1-butanol2011

    • Author(s)
      則竹香菜子,秋利彦,加藤千鶴,白鳥典,上村公一
    • Organizer
      第95回日本法医学会
    • Place of Presentation
      福島
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] Methamphetamine-caused cytotoxic effects involves macropinocytosis in differentiated SH-SY5Y cells2011

    • Author(s)
      奈良明奈, 秋利彦, 船越丈司, 鵜沼香奈, 上村公一
    • Organizer
      第95回日本法医学会
    • Place of Presentation
      福島
    • Year and Date
      2011-06-15
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] ヒト神経芽細胞腫由来SH-SY5Yにおける虚血再灌流時のチロシン水酸化酵素の発現誘導2011

    • Author(s)
      秋利彦、船越丈司、鵜沼香奈、上村公一
    • Organizer
      第95回日本法医学会
    • Place of Presentation
      福島
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] 硫化水素による心筋障害の検討2010

    • Author(s)
      白鳥典、船越丈司、鵜沼香奈、秋利彦、上村公一
    • Organizer
      第79回日本法医学会学術関東地方集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] 心筋細胞における硫化水素の毒性の検討2010

    • Author(s)
      白鳥典、船越丈司、鵜沼香奈、秋利彦、上村公一
    • Organizer
      第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21590733
  • [Presentation] Neurotoxic effects of norephedrine in SH-SY5Y humanneuroblastoma cells2010

    • Author(s)
      船越丈司、内田恭子、奈良明奈、白鳥典、則竹香菜子、鵜沼香奈、秋利彦、上村公一
    • Organizer
      第33回日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] 低酸素による細胞死に対するグルコースの効果は、濃度により抑制的から促進的に変動する2010

    • Author(s)
      秋利彦 、奈良明奈、船越丈司、上村公一
    • Organizer
      第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] 心筋細胞における硫化水素の毒性の検討2010

    • Author(s)
      白鳥典, 船越丈司, 鵜沼香奈, 秋利彦, 上村公一
    • Organizer
      第83回日本生化学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-21590733
  • [Presentation] 覚せい剤原料ノルエフェドリンによる神経細胞毒性機序の検討2010

    • Author(s)
      船越丈司,秋利彦,鵜沼香奈,上村公一
    • Organizer
      第94回日本法医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22590629
  • [Presentation] 硫化水素による心筋細胞障害の検討2010

    • Author(s)
      白鳥典, 船越丈司, 鵜沼香奈, 秋利彦, 上村公一
    • Organizer
      第79回日本法医学会学術関東地方集会
    • Place of Presentation
      東邦大(東京都)
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21590733
  • [Presentation] 硫化水素による心筋細胞障害の検討2010

    • Author(s)
      白鳥典、船越丈司、鵜沼香奈、秋利彦、上村公一
    • Organizer
      第79回日本法医学会学術関東地方集会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21590733
  • [Presentation] Carbon monoxide suppress myocardial injury due to ischemia-reperfusion2006

    • Author(s)
      Nakamura M, Uemura K, Ohno H, Liu S, Yoshida K
    • Organizer
      The 90th annual meeting of Japanese Society of Legal Medicine
    • Place of Presentation
      Fukuoka
    • Year and Date
      2006-04-27
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Presentation] Carbon monoxide protects cardiomyogenic H9c2 cells against ischemic death by inhibiting L-type Ca^<2+> channel2006

    • Author(s)
      Uemura K, Adachi-Akahane S, Yoshida K.
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      京都
    • Year and Date
      2006-06-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Presentation] 一酸化炭素による心筋虚血再灌流障害の抑制2006

    • Author(s)
      中村美穂子, 上村公一, 大野博, 劉爽, 吉田謙一
    • Organizer
      第90次日本法医学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2006-04-27
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Presentation] Carbon monoxide protects cardiomyogenic H9c2 cells against ischemic death by inhibiting L-type Ca^<2+> channel2006

    • Author(s)
      Uemura K, Adachi-Akahane S, Yoshida K
    • Organizer
      20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Year and Date
      2006-06-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390204
  • [Presentation] マウス心房細胞由来HL-1細胞の亜砒酸誘導性アポトーシスにおけるユビキチン-プロテアソーム系の抑制作用

    • Author(s)
      渡邉 まゆ美、船越 丈司、鵜沼 香奈、秋 利彦、上村 公一
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25460863
  • 1.  YOSHIDA KEN-ICHI (40166947)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 33 results
  • 2.  FUNAKOSHI Takeshi (40444715)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 52 results
  • 3.  AKI Toshihiko (60304474)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 57 results
  • 4.  SHINTANI Kaori (50345047)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 23 results
  • 5.  KIMURA Hiroko (00053299)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  Yoshimoto Kanji (70111903)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  池谷 博 (30292874)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 8.  SAKA Kanju (30447388)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 9.  HARADA Kazuki (00253146)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  UEYAMA Takashi (50264875)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 11.  MORIMOTO Keiko (30220081)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  櫻田 宏一 (10334228)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 13.  峰岸 沙希 (00882820)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 14.  鵜沼 香奈 (30586425)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 15.  UEDA Shuichi (60150570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  WATANABE Yoshihisa (50363990)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  NAGAO Masataka (80227991)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KOMURA Setsuo (30025598)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  YASUHARA Masahiro (60305604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TAKAHASHI Kou (90363803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 21.  木内 貴弘 (10260481)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  西内 啓 (00530669)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  青木 則明 (50255270)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  中園 一郎 (30108287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  舟山 眞人 (40190128)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  高坂 友和 (20551469)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 27.  戸谷 麻衣子 (10900045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 28.  井上 郁 (60628642)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  WATANABE Ryo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 30.  吉本 寛治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  則竹 香菜子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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