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Tobe Kazuyuki  戸邉 一之

ORCIDConnect your ORCID iD *help
… Alternative Names

TOBE Kazuyuki  戸辺 一之

戸部 一之  トベ カズユキ

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Researcher Number 30251242
Other IDs
External Links
Affiliation (Current) 2025: 富山大学, 学術研究部医学系, 特別研究教授
Affiliation (based on the past Project Information) *help 2024: 富山大学, 学術研究部医学系, 特別研究教授
2019 – 2024: 富山大学, 学術研究部医学系, 教授
2012 – 2018: 富山大学, 大学院医学薬学研究部(医学), 教授
2013: 富山大学, 医学薬学研究部(医学), 教授
2010 – 2012: 富山大学, 大学院・医学薬学研究部(医学), 教授 … More
2009 – 2011: University of Toyama, 医学薬学研究部(医学), 教授
2007: 富士大学, 医学部・第一内科, 教授
2007: Toyama Univ. School Med., Dept Med., Professor
2007: Toyama University, Graduate School of Medicine and Pharmaceutical Sciencse for Research, Professor
2007: 東京大学, 医学部附属病院, 教授
2006: 東京大学, 医学部附属病院, 准教授
2006: 東京大学, 大学院・糖尿病代謝内科, 講師
2003 – 2006: the University of Tokyo, faculty of Medicine, Lecturer, 医学部附属病院, 講師
2005: 東京大学, 医学部付属病院, 講師
2005: 東京大学, 大学院・医学部, 助教授
2004: University of Tokyo Hospital, Department of Metabolic Diseases, Special Assistant, 医学部附属病院糖尿病・代謝内科, 講師
2003 – 2004: 東京大学, 医学部・附属病院, 講師
2003: 東京大学, 医学部付属病院, 講師
2001 – 2002: University of Tokyo, Faculty of Medicin research associate, 医学部附属病院, 助手
1995 – 2001: University of Tokyo, Assistant, 医学部・附属病院, 助手
1998 – 1999: 東京大学, 医学部附属病院, 助手
1997: 東京大学, 医学部・付属病院, 助手
1996: 東京大学, 医学部附属病院, 助手
1993 – 1995: 東京大学, 医学部(病), 助手 Less
Review Section/Research Field
Principal Investigator
Metabolomics / Metabolomics / 内分泌・代謝学 / Basic Section 54040:Metabolism and endocrinology-related
Except Principal Investigator
Metabolomics / Circulatory organs internal medicine / Metabolomics / Biological Sciences / Basic Section 54040:Metabolism and endocrinology-related / 内分泌・代謝学 … More / Basic Section 56070:Plastic and reconstructive surgery-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 58010:Medical management and medical sociology-related / Laboratory animal science / Orthopaedic surgery / Respiratory organ internal medicine / Medical genome science Less
Keywords
Principal Investigator
インスリン抵抗性 / インスリン受容体 / PPARγ / IRS-2 / 糖尿病 / インスリン受容体基質 / insulin resistance / 肥満 / インスリン作用 / チアゾリジン誘導体 … More / diabetes / レプチン / 脂肪細胞 / M2マクロファージ / マクロファージ / 炎症 / 2型糖尿病 / adiponectin / アディポネクチン / insulin receptor / SREBP-1 / leptin / adipocyte / obesity / insulin receptor substrate / 脂肪肝 / レプチン抵抗性 / 発生工学 / IRS-3 / IRS-1 / 動脈硬化 / PI3キナーゼ / IRS-1欠損マウス / 脂質関連マクロファージ / 骨格筋 / サルコペニア / 骨格筋損傷 / フォリスタチン / 間葉系幹細胞 / TGFβ / insulin secretion / High Fat Diet / IRS / β cell proliferation / pancreatic β cell / 増殖 / 高脂肪食 / β細胞の増殖 / インスリン分泌 / 膵β細胞 / metabolic syndrome / atherosclerosis / レプチン抵抗性改善薬 / 代謝症候群 / thiazolidine / adipocytes / resistance / insulin / fatty liver / leptin resistance / thiazolidinedione / IRS proteins / knockout mice / transgenic mice / IRS蛋白 / ノックアウトマウス / トランスジェニックマウス / thiazolidinedione derivatives / トログリタゾン / 抗糖尿病遺伝子 / 抗肥満遺伝子 / チアゾリジニン誘導体 / TNFα / IRS-1 deficient mice / inculin receptor / insulin action / 欠損マウス / インスリン受容体基質1,2 / インスリン受容体基質1欠損マウス / インスリン抵抗 / 脂肪組織 / STEBP-1 / 脂質代謝 / PPARγのリガンド / PPARファミリー / 高血圧 / 高インスリン血症 / インスリン / 接着斑 / 細胞遊走 / 細胞接着 / グリコーゲン合成酵素 / チロシンキナーゼ / SH2蛋白質 / ras … More
Except Principal Investigator
インスリン抵抗性 / 糖尿病 / 肥満 / PPAR / アディポネクチン / PPARγ / 2型糖尿病 / VEGF / IRS-1 / insulin resistance / NIDDM / IRS-2 / 罹患同胞対法 / 脂肪細胞 / 細胞内情報伝達 / 腸内細菌 / diabetes / obesity / reperfusion / 受容体 / アディポカイン / 血管内皮細胞 / 接着分子 / 腸内細菌叢 / adiponectin / autocrine / reoxygenation / hypoxia / ischemia / glucokinase / AMPキナーゼ / 動脈硬化 / アディポネクチン受容体 / 組織内中性脂肪含量 / レプチン / 転写共役因子 / 一塩基多型 / 多因子病 / グルコキナーゼ / 発生工学 / 全ゲノムマッピング / 心筋細胞 / 心筋虚血再灌流障害 / PI3キナーゼ / シグナル伝達 / 糖代謝異常 / Stra13 / receptor / adipokine / AMP kinase / SNP / Pro12Ala遺伝子多型 / PPARγアンタゴニスト / 高脂肪食 / PPARγヘテロ欠損マウス / insulin / IRS / IGF / インスリン / signal transduction / apoptosis / cardiac myocytes / high-fat diet / type 2 diabetes / 罹患同胞対 / インスリン感受性 / インスリン分泌低下 / intracellular signal transduction / 虚血再灌流 / 酸化ストレス / レドックス / 細胞内シグナル伝達 / 糖尿病モデル動物 / 生活習慣病 / ゲノム / DNAチップ / 遺伝子欠損マウス / 脂肪酸燃焼 / 肥大脂肪細胞 / 1塩基多型(SNP) / グリセロールリン酸シャトル / NADHシャトル / 膵β細胞 / グルコース応答性インスリン分泌 / 候補遺伝子アプローチ / MAPキナーゼ / インスリン作用 / 高齢者 / 再生医療 / 脂肪組織由来幹細胞 / 骨格筋 / サルコペニア / 脂肪由来幹細胞 / 脂肪幹細胞 / 樹状細胞 / T細胞 / 自己免疫 / 1型糖尿病 / 腸肝連関 / 食餌誘導性肝がん / IGF1 / FGF21 / CREBH / 成長ホルモン抵抗性 / 栄養吸収 / 肝臓がん / 脂肪肝 / 肝がん / 脂質代謝 / 富山県 / Cペプチド / 生活習慣指導 / Cペプチド / PHR / 腸内細菌叢解析 / 食事解析 / BMI / 健診 / 生活習慣 / メタボリック症候群 / 糖代謝 / 心不全 / 慢性心不全 / 肥満心筋症 / M2マクロファージ / 繊維化 / 心筋症 / CD206 / 代謝産物 / Pancreatic β cells / Signal Transduction / Diabetes Melitus / 膵ベータ細胞 / fat cell / gene / 遺伝子 / translational research / strain / TRS-2 / 自然交配 / 体外受精 / 遺伝的背景 / ノックアウトマウス / 実験動物 / 系統 / インシュリン抵抗性 / トランスレーショナル研究 / 系統育成 / exocytosis / pancreatic beta-cells / 開口放出 / gene targeting / Diabetes / nuclear receptors / glucose uptake / fatty acid oxidation / adiponectin resistance / adiponectin receptors / 脂質代謝異常 / 核内受容体型転写因子 / 糖取り込み / アディポネクチン抵抗性 / affected sib pair / Haplotype / 全ゲノムスキャン / 個人情報匿名化 / 連鎖不平衡 / 相関解析 / ハプロタイプ / 15-deoxy-12.14-PGJ2 / HPLC / small siza adipocytes / thiazolidinediones / adipocyte differentiation / endogenous PPARγ ligands / 3T3L1脂肪細胞 / 内因性リガンド / CBP / アポトーシス / プロスタグランディン / 脂肪細胞分化 / Pro12Ala polymorphism / PPARγ antagonist / Adiponectin / DNA chip / Insulin resistance / Obesity / High-fat diet / Heterozygous PPARγ deficient mice / Retinoid X受容体アンタゴニスト / Creトランスジェニックマウス / floxマウス / PPARγアンタゴニスト(HX531) / DNAチップ技術 / osteoblast / osteoporosis / bone / IGF-I / IRS-1,-2 / 破骨細胞 / 骨芽細胞 / 骨再生 / 骨折 / 骨粗鬆症 / 再生 / 軟骨 / 骨 / bioacive substance / cardiac myocyte / humoral 48ctor / redox / reoxyaenation / bioactive substance / hypoxia reoxygenation / β2 adrenergic receptor / thrifty genes / susceptibility loci / affected sib-pair analysis / a polygenic, multifactorial disorder / 疾患感受性 / ゲノムマッピング / 候補遺伝子 / アミリン / Common NIDDM / インスリン受容体 / ミトコンドリアDNA / B2アドレナリン受容体 / 遺伝子マッピング / PI3-kinase / NADH shuttle / β-cell / knockout mice / ミトコンドリア・グリセロールリン酸脱水素酵素 / リンゴ酸・アスパラギン酸シャトル / 遺伝子ノックアウトマウス / PI3キナーゼp85α調節サブユニット欠損マウス / 低血糖 / グリセロールリン酸シャトル欠損マウス / インスリン依存的糖輸送 / IRS-2欠損マウス / 病態モデル / humoral factor / 虚血再灌流障害 / 虚血・再灌流 / オートクライン / 液性因子 / 低酸素・再酸素化 / anti-cell-adhesion molecule therapy / acute myocardial infarction / angina pectoris / myocardial ischemia / 好中球 / 再灌流障害 / VFGF / 不安定狭心症 / 無症候性心筋虚血 / 虚血再潅流障害 / 抗接着分子療法 / 急性心筋梗塞 / 狭心症 / 心筋虚血再灌流 / insulin action / genetic reconstitution of NIDDM / insulin secretory defect / genetic engineering / シーンターゲティング / グルユキナーゼ / トランスジェニックマウス / 多因子遺伝 / 疾患モデル動物 / インスリン分泌不全 / 熱ショック蛋白 / 肺線維症 / 呼吸器学 / 細胞・組織 / 疾患関連遺伝子 / インターロイキン10 / メタボリックシンドローム / マクロファージ / 脂肪組織 / 代謝学 / 内科系臨床医学 / 好中球エラスターゼ / 生命システム / 虚血性心疾患 / 転写制御 / ゲノム解析 / 臨床情報 / データベース / エネルギー浪費 / 組織特異的遺伝子改変動物 / 脂肪萎縮 / レプチン感受性 / 分化 / RXRアンタゴニスト / 糖尿病感受性遺伝子 / PRARγ / PPARγ2Pro12Ala多型 / β3アドレナリン受容体 / グリコース応答性インスリン分泌 / ピルビン酸 / TCA回路 / 膵島 / GPシャトル欠損マウス / mGPDH欠損マウス / ミトコンドリア型GPDH / インスリン分泌 / PDE3B / Aktキナーゼ / 粗面小胞体 / インスリン含量 / wortmannin / インスリン受容体基質 / 骨格筋グリコーゲン合成酵素 / common NIDDM / ErbB2 / JAKキナーゼ / 細胞増殖 / 乳癌 / プロラクチン / 成長ホルモン / 蛋白チロシンリン酸化 / 糖鎖 / セレクチン / ras / Grb2 / ASH / 細胞内情報伝達系 / 心筋虚血再潅流障害 Less
  • Research Projects

    (58 results)
  • Research Products

    (279 results)
  • Co-Researchers

    (83 People)
  •  The mechanism how adipose tissue M2 macrophages regulate insulin sensitivityPrincipal Investigator

    • Principal Investigator
      戸邉 一之
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      University of Toyama
  •  Elucidation of the mechanism of liver cancer induced by abnormal lipid metabolism in enterohepatic association

    • Principal Investigator
      中川 嘉
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
    • Research Institution
      University of Toyama
  •  Basic research for the development of islet-specific dendritic cell vaccination for type 1 diabetes

    • Principal Investigator
      Chujo Daisuke
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      University of Toyama
  •  The fundamental research of prevention and treatment for sarcopenia using adipose-derived stem cells

    • Principal Investigator
      佐武 利彦
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      University of Toyama
  •  Regulation of glucose metabolism via microbial modification by dietary components

    • Principal Investigator
      Fujisaka Shiho
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      University of Toyama
  •  Development of prevention and progression control methods for metabolic syndrome by introducing a personal health code

    • Principal Investigator
      Honoki Hisae
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58010:Medical management and medical sociology-related
    • Research Institution
      University of Toyama
  •  Depletion of M2-like macrophages promotes recovery from skeletal muscle injury via the disruption of interaction between M2-like macrophages and muscle mesenchymal stem cellsPrincipal Investigator

    • Principal Investigator
      Tobe Kazuyuki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      University of Toyama
  •  M2 macrophages as a novel therapeutic target in high-fat diet-induced cardiomyopathy

    • Principal Investigator
      Yagi Kunimasa
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      University of Toyama
  •  Identification of gut microbiota- derived metabolites and the mechanisms that impair glucose metabolism

    • Principal Investigator
      Fujisaka Shiho
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      University of Toyama
  •  The role of M2-like macrophages in glucose metabolismPrincipal Investigator

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      University of Toyama
  •  The effect of SRT1720 on HSP47 expression in murine bleomycin-induced pulmonary fibrosis

    • Principal Investigator
      YAMADA Toru
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      University of Toyama
  •  Assessing the clinical utility of the genetic information using the genotype data for GWAS-derived type 2 diabetes susceptibility variants in a Japanese population.

    • Principal Investigator
      IWATA MINORU
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical genome science
    • Research Institution
      University of Toyama
  •  Metabolic regulation by adipose tissue macrophage and interleulin-10

    • Principal Investigator
      USUI Isao
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      University of Toyama
  •  Regulation of insulin resistance by adipose tissue M1/M2 macrophages.Principal Investigator

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      University of Toyama
  •  Physiological and pathophysiological roles ofAdiponectin receptors and identification of molecular targets for treatment of life-style related diseases

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Molecular Mechanisms on Pancreatic β cell Proliferation

    • Principal Investigator
      MITSURU Ohsugi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  The systematic analysis on the diseases through the integration of the clinical data with the genomic information

    • Principal Investigator
      NAGAI Ryozo
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  抗生活習慣病因子アディポネクチンの受容体アゴニスト・発現増加剤・切断活生化剤探索

    • Principal Investigator
      山内 敏正
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Animal Experimentation system as an infrastructure to support translational progression of diabetes research to medical practice

    • Principal Investigator
      YOSUYUKI Ohnishi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Analysis of function and signal transduction pathway of resistin using genetically-engineered animals

    • Principal Investigator
      TERAUCHI Yasuo
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Yokohama City University
  •  Dissection of the role of IRS family proteins in the growth and development of pancreatic β cellsPrincipal Investigator

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  Physiological and pathophysiological roles and signal transduction of adiponectin receptors

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Differentiation, proliferation, and function of pancreatic beta-cells

    • Principal Investigator
      YAMAUCHI toshimasa
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  CBPヘテロ欠損マウスを用いたレプチン非依存性の新規エネルギー・糖・脂質代謝調節経路の同定

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Mechanism of insulin resistance and strategy of treatmentPrincipal Investigator

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  The pathophysiological roles of adiponectin in the regulation of type 2 diabetes, hyperlipidemia and atherosclerosis

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  ゲノムマッピングと候補遺伝子による日本人糖尿病原因遺伝子の同定とその機能解析

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  CBPによる脂肪細胞分化・肥大化及びインスリン感受性の調節メカニズム

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  SREBP-1の制御機構の解明と抑制薬の開発Principal Investigator

    • Principal Investigator
      戸辺 一之
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Dissection of the Mechanism of Diabetes by Genetically Engineered AnimalsPrincipal Investigator

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  PPARγ antagonist ameliorates obesity, insulin resistance and atherosclerosis.Principal Investigator

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      the University of Tokyo
  •  マイクロサテライトマーカーを用いた罹患同胞対法による糖尿病原因遺伝子のマッピング

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  罹患同胞対法・全ゲノムマッピングによる日本人糖尿病原因遺伝子の同定とその機能解析

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  The study for molecular mechanisms of obesity, insulin resistance and atherosclerosis in the PPAR gamma deficient mice

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Development of novel diagnostic and therapeutic strategies for obesity and insulin resistance by identification of endogenous PPARγ ligands

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Identification of type 2 diabetes susceptibility genes in the Japanese population by genome mapping and candidate gene approach and functional analysis

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tokyo
  •  Purification and Identification of the Bioactive Subs tance That Mediates Cardiac Response to the Ischemia Reperfusion Stresses and Development of Treatment

    • Principal Investigator
      SEKO Yoshinori
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tokyo
  •  Mechanism of regulation of bone metabolism by insulin receptor substrates (IRS-1 and IRS-2)

    • Principal Investigator
      KONO Shinjiro, 東 成一, 小崎 慶介
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  発癌に連なるチロシンキナーゼの情報伝達系の異常とその分子機構の解明に関する研究

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  サテライトマーカーを用いた罹患同胞対法による糖尿病原因遺伝子のマッピング

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  動脈硬化発症におけるインスリン抵抗性の役割の解明Principal Investigator

    • Principal Investigator
      戸辺 一之
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  PPARγの内因性リガンドの精製と同定Principal Investigator

    • Principal Investigator
      戸辺 一之
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  β細胞におけるPI3キナーゼを介するシグナル伝達の病態生理学的意義の検討

    • Principal Investigator
      門脇 孝
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Dissection of the Mechanism of Insulin Resistance by Transgenic and knockout Mice TechnologyPrincipal Investigator

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Metabolomics
    • Research Institution
      University of Tokyo
  •  Elucidation of the Molecular Mechanism of Cardiac Response to the Ischemia Reperfusion Stresses and Establishment of Treatment Based on the Molecular Mechanism

    • Principal Investigator
      SEKO Yoshinori
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Approach to the pathogenesis of NIDDM using knockout mouse models.

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Dissection of the Mechanism of Obesity-induced Insulin ResistancePrincipal Investigator

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  Identification of susceptibility genes for type 2 diabetes in the Japanese using affected sib pair analysis

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  心筋虚血再灌流障害における細胞内情報伝達機構の解明および抗接着分子療法の確立

    • Principal Investigator
      世古 義規
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Dissection of the Mechanism of Obesity-induced Insullin ResistancePrincipal Investigator

    • Principal Investigator
      TOBE Kazuyuki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  心筋虚血再灌流障害に対する抗接着分子療法の確立および心筋細胞応答の分子機構の解析

    • Principal Investigator
      世古 義規
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  糖尿病におけるインスリン抵抗性の機序の解明-グリコーゲン合成酵素の活性化の分子機構Principal Investigator

    • Principal Investigator
      戸辺 一之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Development of Molecular Biologic Diagnostic and Therapeutic Method of Asymptomatic Myocardial Ischemia and Unstable Angina

    • Principal Investigator
      SEKO Yoshinori
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tokyo
  •  受容体チロシンキナーゼによるシグナル伝達と細胞増殖・癌化における役割とその制御

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  心筋虚血再灌流障害の細胞内・細胞間分子機構の解明とそれに基づいた予防法の確立

    • Principal Investigator
      世古 義則
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  インスリン受容体基質1のインスリン作用における役割Principal Investigator

    • Principal Investigator
      戸辺 一之
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  心筋虚血再潅流障害の分子機構の解明および接着分子タンパクを用いた予防法の確立

    • Principal Investigator
      SEKO Yoshinori
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Generation of Animal Models for Diabetes by Transgenic and Gene Targeting Technology

    • Principal Investigator
      KADOWAKI Takashi
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 Other

All Journal Article Presentation Book Patent

  • [Book] 糖尿病2020

    • Author(s)
      藤坂志帆 戸邉一之
    • Total Pages
      4
    • Publisher
      (株) 杏林舎
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Book] 医学のあゆみ2020

    • Author(s)
      藤坂志帆 渡邊善之 戸邉一之
    • Total Pages
      3
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Book] Pharma Medica2020

    • Author(s)
      藤坂 志帆 戸邉 一之
    • Total Pages
      4
    • Publisher
      株式会社メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Book] 【自然免疫Update-研究最前線】自然免疫の関わる病態と治療への応用 M2マクロファージと疾患.医学のあゆみ2012

    • Author(s)
      薄井勲、戸邉一之
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Book] 最新臨床糖尿病学 上-糖尿病学の最新動向-】糖尿病研究の進歩 インスリン作用およびインスリン抵抗性発現機序 インスリン抵抗性発現の分子機構 インスリン抵抗性における炎症の役割.日本臨床2012

    • Author(s)
      薄井勲、戸邉一之
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Book] 脂肪組織におけるマクロファージとインスリン抵抗性.Diabetes Journal2011

    • Author(s)
      薄井勲、藤坂志帆,戸邉一之
    • Publisher
      協和企画
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Book] 2型糖尿病のインスリン抵抗性における炎症の役割.日本臨床2011

    • Author(s)
      薄井勲、戸邉一之
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Book] インスリン作用発現とその制御機構.日本臨床2011

    • Author(s)
      薄井勲、戸邉一之
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Book] 脂肪組織でのインスリン作用とインスリン抵抗性.ホルモンと臨床2011

    • Author(s)
      薄井勲、戸邉一之
    • Publisher
      医学の世界社
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Book] Bio Chnica2010

    • Author(s)
      藤坂志帆, 薄井勲, 戸邉一之
    • Publisher
      北隆館
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Book] Medicina2010

    • Author(s)
      藤坂志帆, 浦風雅春, 戸邉一之
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Book] 糖尿病学の進歩2010第44集2010

    • Author(s)
      薄井勲, 戸邉一之
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Book] 糖尿病学2010

    • Author(s)
      薄井勲, 藤坂志帆, 戸邉一之
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Book] 糖尿病ナビゲーター(第2版)2010

    • Author(s)
      薄井勲, 戸邉一之
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Book] カレントテラピー2009

    • Author(s)
      藤坂志帆、薄井勲、浦風雅春、戸辺一之
    • Total Pages
      5
    • Publisher
      ライフメディコム
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Book] 医学のあゆみ2009

    • Author(s)
      薄井勲、戸辺一之
    • Total Pages
      3
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Journal Article] Impact of Vancomycin Treatment and Gut Microbiota on Bile Acid Metabolism and the Development of Non-Alcoholic Steatohepatitis in Mice2023

    • Author(s)
      Kasai Kaichi、Igarashi Naoya、Tada Yuki、Kani Koudai、Takano Shun、Yanagibashi Tsutomu、Usui-Kawanishi Fumitake、Fujisaka Shiho、Watanabe Shiro、Ichimura-Shimizu Mayuko、Takatsu Kiyoshi、Tobe Kazuyuki、Tsuneyama Koichi、Furusawa Yukihiro、Nagai Yoshinori
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 4 Pages: 4050-4050

    • DOI

      10.3390/ijms24044050

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K05466, KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-20K08882, KAKENHI-PROJECT-20K19676
  • [Journal Article] The gut microbiome: a core regulator of metabolism2023

    • Author(s)
      Fujisaka Shiho、Watanabe Yoshiyuki、Tobe Kazuyuki
    • Journal Title

      Journal of Endocrinology

      Volume: 256 Issue: 3

    • DOI

      10.1530/joe-22-0111

    • Open Access
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Journal Article] Semaglutide once a week in adults with overweight or obesity, with or without type 2 diabetes in an east Asian population (STEP 6): a randomised, double-blind, double-dummy, placebo-controlled, phase 3a trial2022

    • Author(s)
      Kadowaki Takashi、Isendahl Joakim、Khalid Usman、Lee Sang Yeoup、Nishida Tomoyuki、Ogawa Wataru、Tobe Kazuyuki、Yamauchi Toshimasa、Lim Soo
    • Journal Title

      The Lancet Diabetes & Endocrinology

      Volume: 10 Issue: 3 Pages: 193-206

    • DOI

      10.1016/s2213-8587(22)00008-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] Fragmented QRS on electrocardiography as a predictor for diastolic cardiac dysfunction in type?2 diabetes2022

    • Author(s)
      Yagi Kunimasa、Imamura Teruhiko、Tada Hayato、Liu Jianhui、Miyamoto Yukiko、Ohbatake Azusa、Ito Naoko、Shikata Masataka、Enkaku Asako、Takikawa Akiko、Honoki Hisae、Fujisaka Shiho、Chujo Daisuke、Origasa Hideki、Kinugawa Koichiro、Tobe Kazuyuki
    • Journal Title

      Journal of Diabetes Investigation

      Volume: - Issue: 6 Pages: 1052-1061

    • DOI

      10.1111/jdi.13759

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-21K10300, KAKENHI-PROJECT-22K10875, KAKENHI-PROJECT-20K08882
  • [Journal Article] Perioperative C‐peptide index is associated with the status of diabetes management after pancreatectomy2022

    • Author(s)
      Shikata Masataka、Chujo Daisuke、Enkaku Asako、Takikawa‐Nishida Akiko、Honoki Hisae、Yamada‐Matsukoshi Shinnosuke、Nakagawa‐Yokoyama Maki、Kamigishi Miki、Inagawa Shinya、Fujisaka Shiho、Yagi Kunimasa、Shibuya Kazuto、Fujii Tsutomu、Tobe Kazuyuki
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 13 Issue: 10 Pages: 1685-1694

    • DOI

      10.1111/jdi.13861

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K10300, KAKENHI-PROJECT-22K10875, KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-20K08882
  • [Journal Article] A New Method for Albuminuria Measurement Using a Specific Reaction between Albumin and the Luciferin of the Firefly Squid Watasenia scintillans2022

    • Author(s)
      Ishimoto Tetsuya、Okada Takuya、Fujisaka Shiho、Yagi Kunimasa、Tobe Kazuyuki、Toyooka Naoki、Mori Hisashi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 15 Pages: 8342-8342

    • DOI

      10.3390/ijms23158342

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K10300, KAKENHI-PROJECT-22K10875, KAKENHI-PROJECT-20K07712, KAKENHI-PROJECT-20K08882
  • [Journal Article] Depletion of CD206+ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration2022

    • Author(s)
      Nawaz Allah et al.
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 7058-7058

    • DOI

      10.1038/s41467-022-34191-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19753, KAKENHI-PROJECT-22K19534, KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-21H02713, KAKENHI-PROJECT-20K08882, KAKENHI-PROJECT-19H04063, KAKENHI-PROJECT-23K24108, KAKENHI-PROJECT-23K24762, KAKENHI-PROJECT-20H03679, KAKENHI-PROJECT-20K20655
  • [Journal Article] Increased Number of Mucosal-Associated Invariant T Cells Is Associated with the Inhibition of Nonalcoholic Fatty Liver Disease in High Fat Diet-Fed Mice.2022

    • Author(s)
      Kishi H, Usui I, Jojima T, Fujisaka S, Wakamatsu S, Mizunuma-Inoue Y, Niitani T, Sakurai S, Iijima T, Tomaru T, Tobe K, Aso Y.
    • Journal Title

      Int J Mol Sci.

      Volume: 23 Issue: 23 Pages: 15309-15309

    • DOI

      10.3390/ijms232315309

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-20K08882, KAKENHI-PROJECT-20K08893
  • [Journal Article] A Comparison of Line Blots, Enzyme-linked Immunosorbent, and RNA-immunoprecipitation Assays of Antisynthetase Antibodies in Serum Samples from 44 Patients2022

    • Author(s)
      Shinoda Koichiro、Okumura Maiko、Yamaguchi Satoshi、Matsui Atsushi、Tsuda Reina、Hounoki Hiroyuki、Suzuki Shigeaki、Tobe Kazuyuki
    • Journal Title

      Intern. Med.

      Volume: 61 Issue: 3 Pages: 313-322

    • DOI

      10.2169/internalmedicine.7824-21

    • NAID

      130008150353

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2022-02-01
    • Language
      English
    • Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] Isoliquiritigenin Attenuates Adipose Tissue Inflammation and Metabolic Syndrome by Modifying Gut Bacteria Composition in Mice2022

    • Author(s)
      Ishibashi Riko、Furusawa Yukihiro、Honda Hiroe、Watanabe Yasuharu、Fujisaka Shiho、Nishikawa Miyu、Ikushiro Shinichi、Kurihara Shin、Tabuchi Yoshiaki、Tobe Kazuyuki、Takatsu Kiyoshi、Nagai Yoshinori
    • Journal Title

      Molecular Nutrition & Food Research

      Volume: - Issue: 10 Pages: 2101119-2101119

    • DOI

      10.1002/mnfr.202101119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07076, KAKENHI-PROJECT-19K09019, KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-20K08882, KAKENHI-PROJECT-22K07005
  • [Journal Article] Case Series of Pleomorphic Carcinoma of the Lung Treated With Immune Checkpoint Inhibitors2021

    • Author(s)
      HAYASHI KANA、TOKUI KOTARO、INOMATA MINEHIKO、AZECHI KENJI、MIZUSHIMA ISAMI、TAKATA NAOKI、TAKA CHIHIRO、OKAZAWA SEISUKE、KAMBARA KENTA、IMANISHI SHINGO、MIWA TOSHIRO、HAYASHI RYUJI、MATSUI SHOKO、NOMURA SATOSHI、TOBE KAZUYUKI
    • Journal Title

      In Vivo

      Volume: 35 Issue: 3 Pages: 1687-1692

    • DOI

      10.21873/invivo.12428

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] Fulminant type 1 diabetes patients display high frequencies of IGRP-specific type 1 CD8+ T cells2021

    • Author(s)
      Chujo Daisuke、Kawabe Akitsu、Matsushita Maya、Tsutsumi Chiharu、Haseda Fumitaka、Imagawa Akihisa、Hanafusa Toshiaki、Ueki Kohjiro、Kajio Hiroshi、Yagi Kunimasa、Tobe Kazuyuki、Shimoda Masayuki
    • Journal Title

      Clinical Immunology

      Volume: 233 Pages: 108893-108893

    • DOI

      10.1016/j.clim.2021.108893

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] Generation and characterization of a Meflin-CreERT2 transgenic line for lineage tracing in white adipose tissue2021

    • Author(s)
      Kuwano Takahide, Izumi Hironori, Aslam Muhammad Rahil, Igarashi Yoshiko, Bilal Muhammad, Nishimura Ayumi, Watanabe Yoshiyuki, Nawaz Allah, Kado Tomonobu, Ikuta Koichi, Yamamoto Seiji, Sasahara Masakiyo, Fujisaka Shiho, Yagi Kunimasa, Mori Hisashi, Tobe Kazuyuki
    • Journal Title

      PLOS ONE

      Volume: 16 Issue: 3 Pages: e0248267-e0248267

    • DOI

      10.1371/journal.pone.0248267

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-18K06888, KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-19K19407, KAKENHI-PROJECT-20K22733, KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-21H02713, KAKENHI-PROJECT-21K10300
  • [Journal Article] Astaxanthin, a Marine Carotenoid, Maintains the Tolerance and Integrity of Adipose Tissue and Contributes to Its Healthy Functions.2021

    • Author(s)
      Nawaz A, Nishida Y, Takikawa A, Fujisaka S, Kado T, Aminuddin A, Bilal M, Jeelani I, Rahil AM, Nishimura A, Kuwano T, Watanabe Y, Igarashi Y, Okabe K, Saeed A, Manzoor A, Usui I, Yagi K, Nakagawa T, Tobe K.
    • Journal Title

      Nutrients

      Volume: 13 Issue: 12 Pages: 4374-4374

    • DOI

      10.3390/nu13124374

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-20K22733, KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-20K08882, KAKENHI-PROJECT-21K10300, KAKENHI-PROJECT-20K20655
  • [Journal Article] Diastolic Cardiac Function Improvement by Liraglutide Is Mainly Body Weight Reduction Dependent but Independently Contributes to B-Type Natriuretic Peptide Reduction in Patients with Type 2 Diabetes with Preserved Ejection Fraction2021

    • Author(s)
      Yagi Kunimasa、Imamura Teruhiko、Tada Hayato、Chujo Daisuke、Liu Jianhui、Shima Yuuki、Ohbatake Azusa、Miyamoto Yukiko、Okazaki Satoko、Ito Naoko、Nakano Kaoru、Shikata Masataka、Enkaku Asako、Takikawa Akiko、Honoki Hisae、Fujisaka Shiho、Origasa Hideki、Tobe Kazuyuki
    • Journal Title

      Journal of Diabetes Research

      Volume: 2021 Pages: 1-10

    • DOI

      10.1155/2021/8838026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-21K10300
  • [Journal Article] Correction to: Safety and Effectiveness of Ipragliflozin in Elderly Versus Non-elderly Japanese Patients with Type 2 Diabetes: Subgroup Analysis of STELLA-LONG TERM2021

    • Author(s)
      Nakamura Ichiro、Maegawa Hiroshi、Tobe Kazuyuki、Uno Satoshi
    • Journal Title

      Diabetes Therapy

      Volume: 12 Issue: 6 Pages: 1765-1768

    • DOI

      10.1007/s13300-021-01073-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] Correction to: Safety and Effectiveness of Ipragliflozin for Type 2 Diabetes in Japan: 12-Month Interim Results of the STELLA-LONG TERM Post-Marketing Surveillance Study2021

    • Author(s)
      Nakamura Ichiro、Maegawa Hiroshi、Tobe Kazuyuki、Uno Satoshi
    • Journal Title

      Advances in Therapy

      Volume: 38 Issue: 8 Pages: 4599-4601

    • DOI

      10.1007/s12325-021-01813-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] TCR function analysis using a novel system reveals the multiple unconventional tumor‐reactive T cells in human breast cancer‐infiltrating lymphocytes2021

    • Author(s)
      Yamaguchi Satoshi、Hamana Hiroshi、Shitaoka Kiyomi、Sukegawa Kenta、Nagata Takuya、Hayee Abdul、Kobayashi Eiji、Ozawa Tatsuhiko、Fujii Tsutomu、Muraguchi Atsushi、Tobe Kazuyuki、Kishi Hiroyuki
    • Journal Title

      European Journal of Immunology

      Volume: 51 Issue: 9 Pages: 2306-2316

    • DOI

      10.1002/eji.202049070

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-21H02962, KAKENHI-PROJECT-21H02966, KAKENHI-PROJECT-21K18261
  • [Journal Article] Gut microbiota, determined by dietary nutrients, drive modification of the plasma lipid profile and insulin resistance.2021

    • Author(s)
      Watanabe Y, Fujisaka S, Ikeda K, Ishikawa M, Yamada T, Nawaz A, Kado T, Kuwano T, Nishimura A, Bilal M, Liu J, Yagi K, Hase K, Tobe K.
    • Journal Title

      iScience

      Volume: 24 Issue: 5 Pages: 102445-102445

    • DOI

      10.1016/j.isci.2021.102445

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-20K22733, KAKENHI-PROJECT-20H00509, KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-20K08882, KAKENHI-PROJECT-21K10300, KAKENHI-PROJECT-21K20896
  • [Journal Article] Corrigendum to “Suppression of Dynamical Network Biomarker Signals at the Predisease State (Mibyou) before Metabolic Syndrome in Mice by a Traditional Japanese Medicine (Kampo Formula) Bofutsushosan”2021

    • Author(s)
      Koizumi Keiichi、Oku Makito、Hayashi Shusaku、Inujima Akiko、Shibahara Naotoshi、Chen Luonan、Igarashi Yoshiko、Tobe Kazuyuki、Saito Shigeru、Kadowaki Makoto、Aihara Kazuyuki
    • Journal Title

      Evidence-Based Complementary and Alternative Medicine

      Volume: 2021 Pages: 1-1

    • DOI

      10.1155/2021/9760307

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] Safety and Effectiveness of Ipragliflozin in Elderly Versus Non-elderly Japanese Patients with Type?2 Diabetes: Subgroup Analysis of STELLA-LONG?TERM2021

    • Author(s)
      Nakamura Ichiro、Maegawa Hiroshi、Tobe Kazuyuki、Uno Satoshi
    • Journal Title

      Diabetes Therapy

      Volume: 12 Issue: 5 Pages: 1359-1378

    • DOI

      10.1007/s13300-021-01042-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] High prevalence of fragmented QRS on electrocardiography in Japanese patients with diabetes irrespective of metabolic syndrome2021

    • Author(s)
      Yagi Kunimasa、Nagata Yoshiki、Yamagami Takashi、Chujo Daisuke、Kamigishi Miki、Yokoyama‐Nakagawa Maki、Shikata Masataka、Enkaku Asako、Takikawa‐Nishida Akiko、Honoki Hisae、Fujisaka Shiho、Origasa Hideki、Tobe Kazuyuki
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 12 Issue: 9 Pages: 1680-1688

    • DOI

      10.1111/jdi.13524

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-21K10300
  • [Journal Article] Genome-Wide Association Studies Identify Two Novel Loci Conferring Susceptibility to Diabetic Retinopathy in Japanese Patients with Type 2 Diabetes.2021

    • Author(s)
      Imamura M,・・・・・・・・・ Yamauchi T, Tobe K, Maegawa H, Kadowaki T, Maeda S.
    • Journal Title

      Hum Mol Genet.

      Volume: なし Issue: 8 Pages: 716-726

    • DOI

      10.1093/hmg/ddab044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-20H03730
  • [Journal Article] Effect of ipragliflozin on liver function in Japanese type 2 diabetes mellitus patients: subgroup analysis of a 3-year post-marketing surveillance study (STELLA-LONG TERM).2021

    • Author(s)
      Tobe K, Maegawa H, Nakamura I, Uno S.
    • Journal Title

      Endocr J

      Volume: 68 Pages: 905-918

    • NAID

      130008079305

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] Type 1 diabetes woman with repeated miscarriages successfully gave birth after introducing an insulin pump with a predictive low glucose suspend feature2021

    • Author(s)
      Honoki Hisae、Yagi Kunimasa、Tsuda Sayaka、Wada Tsutomu、Enkaku Asako、Nakagawa-Yokoyama Maki、Kamigishi Miki、Shikata Masataka、Takikawa-Nishiday Akiko、Fujisaka Shiho、Chujo Daisuke、Sasaoka Toshiyasu、Nakashima Akitoshi、Saito Shigeru、Tobe Kazuyuki
    • Journal Title

      Diabetology International

      Volume: 12 Issue: 3 Pages: 324-329

    • DOI

      10.1007/s13340-020-00489-9

    • NAID

      40022593484

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-21K10300, KAKENHI-PROJECT-21K16764
  • [Journal Article] Immune Checkpoint Inhibitor for Non-small Cell Lung Cancer With Negative or Low Tumor PD-L1 Expression2021

    • Author(s)
      INOMATA MINEHIKO、TAKATA NAOKI、MIZUSHIMA ISAMI、AZECHI KENJI、HAYASHI KANA、TOKUI KOTARO、TAKA CHIHIRO、OKAZAWA SEISUKE、KAMBARA KENTA、IMANISHI SHINGO、MIWA TOSHIRO、HAYASHI RYUJI、MATSUI SHOKO、TOBE KAZUYUKI
    • Journal Title

      Cancer Diagnosis & Prognosis

      Volume: 1 Issue: 3 Pages: 173-177

    • DOI

      10.21873/cdp.10023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Journal Article] Fate of adipocyte progenitors during adipogenesis in mice fed a high-fat diet2021

    • Author(s)
      Bilal M, Nawaz A, Kado T, Rahil Aslam M, Igarashi Y, Nishimura A, Watanabe A, Kuwano T, Liu J, Miwa H, Era T, Ikuta K, Imura J, Yagi K, Nakagawa T, Fujisaka S, Tobe K.
    • Journal Title

      Molecular Metabolism

      Volume: 54 Pages: 101328-101328

    • DOI

      10.1016/j.molmet.2021.101328

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-20K21525, KAKENHI-PROJECT-20K22733, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-20K20655
  • [Journal Article] Gut microbiota, determined by dietary nutrients, drives modification of the plasma lipid profile and insulin resistance.2021

    • Author(s)
      Watanabe Y, Fujisaka S, Ikeda K, Ishikawa M, Yamada T, Nawaz A, Kado T, Kuwano T, Nishimura A, Bilal M, Liu J, Yagi K, Hase K, Tobe K
    • Journal Title

      iScience

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Journal Article] Family history of diabetes in both parents is strongly associated with impaired residual β-cell function in Japanese type 2 diabetes patients2020

    • Author(s)
      Iwata Minoru, Kamura Yutaka, Honoki Hisae, Kobayashi Kaori, Ishiki Manabu, Yagi Kunimasa, Fukushima Yasuo, Takano Atsuko, Kato Hiromi, Murakami Shihou, Higuchi Kiyohiro, Kobashi Chikaaki, Fukuda Kazuhito, Koshimizu Yukiko, Tobe Kazuyuki
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 11 Issue: 3 Pages: 564-572

    • DOI

      10.1111/jdi.13176

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-18K08505
  • [Journal Article] High prevalence of fragmented QRS on electrocardiography in Japanese subjects with diabetes irrespective of metabolic syndrome2020

    • Author(s)
      Yagi Kunimasa、Nagata Yoshiki、Yamagami Takashi、Kamigishi Miki、Yokoyama Maki Nakagawa、Shikata Masataka、Enkaku Asako、Nishida Akiko Takikawa、Honoki Hisae、Fujisaka Shiho、Chujo Daisuke、Origasa Hideki、Tobe Kazuyuki
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 12 Pages: 1680-1688

    • DOI

      10.21203/rs.3.rs-123784/v1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204
  • [Journal Article] Distinct Phenotypes of Islet Antigen-Specific CD4+ T Cells Among the 3 Subtypes of Type 1 Diabetes2020

    • Author(s)
      Chujo Daisuke, Kawabe Akitsu, Matsushita Maya, Takahashi Nobuyuki, Tsutsumi Chiharu, Haseda Fumitaka, Imagawa Akihisa, Hanafusa Toshiaki, Ueki Kohjiro, Kajio Hiroshi, Yagi Kunimasa, Tobe Kazuyuki, Shimoda Masayuki
    • Journal Title

      The Journal of Clinical Endocrinology & Metabolism

      Volume: 105 Issue: 10 Pages: 3141-3151

    • DOI

      10.1210/clinem/dgaa447

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-18K08505
  • [Journal Article] Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in mice with diet-induced obesity2020

    • Author(s)
      Fujisaka Shiho、Usui Isao、Nawaz Allah、Igarashi Yoshiko、Okabe Keisuke、Furusawa Yukihiro、Watanabe Shiro、Yamamoto Seiji、Sasahara Masakiyo、Watanabe Yoshiyuki、Nagai Yoshinori、Yagi Kunimasa、Nakagawa Takashi、Tobe Kazuyuki
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 5544-5544

    • DOI

      10.1038/s41598-020-62506-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18F18102, KAKENHI-PROJECT-17K08653, KAKENHI-PROJECT-17K09821, KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-18K07441, KAKENHI-PROJECT-18K08505
  • [Journal Article] Anti-programmed death ligand 1 therapy-induced type 1 diabetes presenting with multiple islet-related autoantibodies2020

    • Author(s)
      Honoki Hisae, Yagi Kunimasa, Kambara Kenta, Chujo Daisuke, Shikata Masataka, Enkaku Asako, Takikawa-Nishida Akiko, Liu Jianhui, Fujisaka Shiho, Tobe Kazuyuki
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 11 Issue: 1 Pages: 253-254

    • DOI

      10.1111/jdi.13099

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-18K08505
  • [Journal Article] NAD+ Metabolism Regulates Preadipocyte Differentiation by Enhancing α-Ketoglutarate-Mediated Histone H3K9 Demethylation at the PPARγ Promoter2020

    • Author(s)
      Okabe Keisuke、Nawaz Allah、Nishida Yasuhiro、Yaku Keisuke、Usui Isao、Tobe Kazuyuki、Nakagawa Takashi
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 8 Pages: 586179-586179

    • DOI

      10.3389/fcell.2020.586179

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K20655, KAKENHI-PROJECT-20K22733, KAKENHI-PROJECT-18K16193, KAKENHI-PROJECT-18K17921, KAKENHI-PROJECT-20H03730
  • [Journal Article] Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway2020

    • Author(s)
      Nishida Yasuhiro、Nawaz Allah、Kado Tomonobu、Takikawa Akiko、Igarashi Yoshiko、Onogi Yasuhiro、Wada Tsutomu、Sasaoka Toshiyasu、Yamamoto Seiji、Sasahara Masakiyo、Imura Johji、Tokuyama Kumpei、Usui Isao、Nakagawa Takashi、Fujisaka Shiho、Kunimasa Yagi、Tobe Kazuyuki
    • Journal Title

      Journal of Cachexia, Sarcopenia and Muscle

      Volume: 11 Issue: 1 Pages: 241-258

    • DOI

      10.1002/jcsm.12530

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18F18102, KAKENHI-PROJECT-17K08653, KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-20H03730
  • [Journal Article] Clinical manifestations of a sporadic maturity-onset diabetes of the young (MODY) 5 with a whole deletion of <i>HNF1B</i> based on 17q12 microdeletion2019

    • Author(s)
      Omura Yoshiyuki、Yagi Kunimasa、Honoki Hisae、Iwata Minoru、Enkaku Asako、Takikawa Akiko、Kuwano Takahide、Watanabe Yoshiyuki、Nishimura Ayumi、Liu Jianhui、Chujo Daisuke、Fujisaka Shiho、Enya Mayumi、Horikawa Yukio、Tobe Kazuyuki
    • Journal Title

      Endocr J

      Volume: 66 Issue: 12 Pages: 1113-1116

    • DOI

      10.1507/endocrj.EJ19-0020

    • NAID

      130007772410

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-18H02779
  • [Journal Article] Macrophage‐specific hypoxia‐inducible factor‐1α deletion suppresses the development of liver tumors in high‐fat diet‐fed obese and diabetic mice2019

    • Author(s)
      Takikawa Akiko、Usui Isao、Fujisaka Shiho、Tsuneyama Koichi、Okabe Keisuke、Nakagawa Takashi、Nawaz Allah、Kado Tomonobu、Jojima Teruo、Aso Yoshimasa、Hayakawa Yoshihiro、Yagi Kunikimi、Tobe Kazuyuki
    • Journal Title

      Journal of Diabetes Investigation

      Volume: in press Issue: 6 Pages: 1-8

    • DOI

      10.1111/jdi.13047

    • NAID

      120006980551

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-18K16193, KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-17K16143, KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204, KAKENHI-PLANNED-17H06398
  • [Journal Article] Sirt1 activator induces proangiogenic genes in preadipocytes to rescue insulin resistance in diet-induced obese mice2018

    • Author(s)
      Nawaz Allah、Mehmood Arshad、Kanatani Yukiko、Kado Tomonobu、Igarashi Yoshiko、Takikawa Akiko、Yamamoto Seiji、Okabe Keisuke、Nakagawa Takashi、Yagi Kunimasa、Fujisaka Shiho、Tobe Kazuyuki
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 11370-11370

    • DOI

      10.1038/s41598-018-29773-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08653, KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204, KAKENHI-PROJECT-18F18102
  • [Journal Article] Ratio of low molecular weight serum adiponectin to the total adiponectin value is associated with type 2 diabetes through its relation to increasing insulin resistance.2018

    • Author(s)
      Iwata M, Hara K, Kamura Y, Honoki H, Fujisaka S, Ishiki M, Usui I, Yagi K, Fukushima Y, Takano A, Kato H, Murakami S, Higuchi K, Kobashi C, Fukuda K, Koshimizu Y, Tobe K.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 3 Pages: e0192609-e0192609

    • DOI

      10.1371/journal.pone.0192609

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09821, KAKENHI-PROJECT-18K08505, KAKENHI-PROJECT-18K10204
  • [Journal Article] CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors2017

    • Author(s)
      Nawaz Allah, , Usui Isao, , et al
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 286-301

    • DOI

      10.1038/s41467-017-00231-1

    • NAID

      120006535075

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-17K08653, KAKENHI-PROJECT-17K09821, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-15K08527
  • [Journal Article] Nmnat3 is not essential for the maintenance of mitochondrial NAD level in vivo.2016

    • Author(s)
      Yamamoto M, Hikosaka K, Mahmood A, Tobe K, Shojaku H, Nakagawa T
    • Journal Title

      PLOS ONE

      Volume: 11(1) Issue: 1 Pages: e0147037-e0147037

    • DOI

      10.1371/journal.pone.0147037

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24689019, KAKENHI-PROJECT-26461327
  • [Journal Article] Deletion of SIRT1 in myeloid cells impairs glucose metabolism with enhancing inflammatory response to adipose tissue hypoxia2016

    • Author(s)
      Akiko Takikawa, Isao Usui , Shiho Fujisaka, Masashi Ikutani, Satoko Senda, Shinpei Hattori, Koichi Tsuneyama, Yukiko Koshimizu, Ran Inoue, Ayumi Tanaka-Hayashi, Takashi Nakagawa, Yoshinori Nagai, Kiyoshi Takatsu, Toshiyasu Sasaoka, Hisashi Mori, Kazuyuki Tobe
    • Journal Title

      Diabetology International

      Volume: 7 Issue: 1 Pages: 59-68

    • DOI

      10.1007/s13340-015-0213-3

    • NAID

      40020774323

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-25461333, KAKENHI-PROJECT-24689019, KAKENHI-PROJECT-26461327
  • [Journal Article] Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.2016

    • Author(s)
      Imamura M, ・・Yamauchi T,・・ Shojima N, ・・Kadowaki T
    • Journal Title

      Nat Commun.

      Volume: 7 Issue: 1 Pages: 10531-10531

    • DOI

      10.1038/ncomms10531

    • NAID

      120006889946

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09409, KAKENHI-PUBLICLY-15H01507, KAKENHI-PLANNED-15H05911, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-15H05670, KAKENHI-PROJECT-26461327, KAKENHI-PROJECT-26000012
  • [Journal Article] M2 macrophages in metabolism.2016

    • Author(s)
      Fujisaka S, Usui I, Nawaz A, Takikawa A, Kado T, Igarashi Y, Tobe K.
    • Journal Title

      Diabetes Int.

      Volume: 7 Issue: 4 Pages: 342-351

    • DOI

      10.1007/s13340-016-0290-y

    • NAID

      40021041341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Journal Article] FTO gene polymorphism is associated with Type 2 diabetes through its effect on increasing the maximum BMI in Japanese men.2016

    • Author(s)
      Kamura Y, Iwata M, Maeda S, Shinmura S, Koshimizu Y, Hounoki H, Fukuda K, Ishiki M, Usui I, Fukushima Y, Takano A, Kato H, Murakami S, Higuchi K, Kobashi C, Tobe K.
    • Journal Title

      PLOS ONE

      Volume: 11(11) Issue: 11 Pages: e0165523-e0165523

    • DOI

      10.1371/journal.pone.0165523

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Journal Article] HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.2016

    • Author(s)
      Takikawa A, Mahmood A, Nawaz A, Kado T, Okabe K, Yamamoto S, Arif A, Senda S, Tsuneyama K, Ikutani M, Watanabe Y, Igarashi Y, Nagai Y, Takatsu K, Koizumi K, Imura J, Goda N, Sasahara M, Matsumoto M, Saeki K, Nakagawa T, Fujisaka S, Usui I, Tobe K.
    • Journal Title

      Diabetes

      Volume: 65(12) Issue: 12 Pages: 3649-3659

    • DOI

      10.2337/db16-0012

    • NAID

      40021380120

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25293093, KAKENHI-PROJECT-26460360, KAKENHI-PROJECT-26461327, KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-16K19532
  • [Journal Article] Pioglitazone Ameliorates Smooth Muscle Cell Proliferation in Cuff-Induced Neointimal Formation by Both Adiponectin-Dependent and -Independent Pathways.2016

    • Author(s)
      Kubota T, Kubota N, Sato H, Inoue M, Kumagai H, Iwamura T, Takamoto I, Kobayashi T, Moroi M, Terauchi Y, Tobe K, Ueki K, Kadowaki T
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 34707-34707

    • DOI

      10.1038/srep34707

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-16H05329, KAKENHI-PROJECT-26461327, KAKENHI-PROJECT-15K07975, KAKENHI-PROJECT-26000012
  • [Journal Article] Calorie restriction-mediated restoration of hypothalamic signal transducer and activator of transcription 3 (STAT3) phosphorylation is not effective for lowering the body weight set point in IRS-2 knockout obese mice.2015

    • Author(s)
      Senda S, Inoue A, Mahmood A, Suzuki R, Kamei N, Kubota N, Watanabe T, Aoyama M, Nawaz A, Ohkuma Y, Tsuneyama K, Koshimizu Y, Usui I, Saeki K, Kadowaki T, Tobe K.
    • Journal Title

      Diabetol Int.

      Volume: Dec;6(4) Pages: 321-35

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Journal Article] Sirtuin1 maintains actin cytoskeleton by deacetylation of cortactin in injured podocytes.2015

    • Author(s)
      Motonishi S, Nangaku M, Wada T, Ishimoto Y, Ohse T, Matsusaka T, Kubota N, Shimizu A, Kadowaki T, Tobe K, Inagi R.
    • Journal Title

      J Am Soc Nephrol.

      Volume: Aug;26(8) Pages: 1939-59

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Journal Article] SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD(+) and Function in Mice.2015

    • Author(s)
      Yoon MJ, Yoshida M, Johnson S, Takikawa A, Usui I, Tobe K, Nakagawa T, Yoshino J, Imai S.
    • Journal Title

      Cell Metab.

      Volume: May 5;21(5) Pages: 706-17

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Journal Article] Replication study for the association of rs7578597 in THADA, rs10886471 in GRK5 and rs7403531 in RASGRP1 with susceptibility to type 2 diabetes in a Japanese population.2015

    • Author(s)
      Sakai K, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Hirotaka Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.
    • Journal Title

      Diabetology International

      Volume: Dec;6(4) Pages: 306-312

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Journal Article] Calorie restriction-mediated restoration of hypothalamic signal transducer and activator of transcription 3 (STAT3) phosphorylation is not effective for lowering the body weight set point in IRS-2 knockout obese mice2015

    • Author(s)
      Senda S, Inoue A, Mahmood A, Suzuki R, Kamei N, Kubota N, Watanabe T, Aoyama M, Nawaz A, Ohkuma Y, Tsuneyama K, Koshimizu Y, Usui I, Saeki K, Kadowaki T and Tobe K.
    • Journal Title

      Diabetology International

      Volume: 6 Issue: 4 Pages: 321-335

    • DOI

      10.1007/s13340-015-0205-3

    • NAID

      40020684042

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24790918, KAKENHI-PROJECT-26461327, KAKENHI-PUBLICLY-25131704, KAKENHI-PROJECT-25461373
  • [Journal Article] Association of serum adiponectin with asthma and pulmonary function in the Japanese population.2015

    • Author(s)
      Hayashikawa Y, Iwata M, Inomata M, Kawagishi Y, Tokui K, Taka C, Kambara K, Okazawa S, Yamada T, Hayashi R, Kamura Y, Okazawa T, Matsui S, Kigawa M, Tobe K.
    • Journal Title

      Endocr J.

      Volume: May 15;62(8) Pages: 695-709

    • NAID

      130005094619

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Journal Article] Replication study in a Japanese population to evaluate the association between 10 SNP loci, identified in European genome-wide association studies, and type 2 diabetes.2015

    • Author(s)
      Matsuba R,, Sakai K, Imamura M, Tanaka Y, Iwata M, Hiroshe H, Kaku K, Maegawa H, WatadaH, Tobe K, Kashiwagi A, Kawamori R, Maeda S.
    • Journal Title

      Plos One

      Volume: 10 Issue: 5 Pages: e0126363-e0126363

    • DOI

      10.1371/journal.pone.0126363

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24510276, KAKENHI-PROJECT-26461390, KAKENHI-PROJECT-15H03097
  • [Journal Article] Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes.2015

    • Author(s)
      Matsuba R, Sakai K, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.
    • Journal Title

      PLoS One.

      Volume: May 7;10(5)

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Journal Article] Deletion of SIRT1 in Myeloid Cells Impairs Glucose Metabolism with Enhancing Inflammatory Response to Adipose Tissue Hypoxia.2015

    • Author(s)
      Takikawa A, Usui I, Fujisaka S, Ikutani M, Senda S, Hattori S, Tsuneyama K, Koshimizu Y, Inoue R, Tanaka-Hayashi A, Nakagawa T, Nagai Y, Takatsu K, Sasaoka T, Mori H, Tobe K.
    • Journal Title

      Diabetology International

      Volume: 未定

    • NAID

      40020774323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Journal Article] SIRT1-Mediated eNAMPT Secretion
from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice.2015

    • Author(s)
      Yoon MJ, Yoshida M, Johnson S, Takikawa A, Usui I, Tobe K, Nakagawa T, Yoshino J, Imai SI.
    • Journal Title

      Cell Metabolism

      Volume: 21(1) Issue: 5 Pages: 1-12

    • DOI

      10.1016/j.cmet.2015.04.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24689019, KAKENHI-PROJECT-26461327
  • [Journal Article] Deficiency of nicotinamide mononucleotide adenylyltransferase 3 (nmnat3) causes Hemolytic anemia by altering the glycolytic flow in mature erythrocytes.2014

    • Author(s)
      Hikosaka K., Ikutani M., Shito M., Kazuma K., Gulshan M., Nagai Y., Takatsu K., Konno K., Tobe K., Kanno H., Nakagawa T.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 289 Issue: 21 Pages: 14796-14811

    • DOI

      10.1074/jbc.m114.554378

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25461609, KAKENHI-PROJECT-26461327
  • [Journal Article] Assessing the clinical utility of a genetic risk score constructed using 49 susceptibility alleles for type 2 diabetes in a Japanese population2013

    • Author(s)
      Imamura M, Shigemizu D, Tsunoda T, Iwata M, Maegawa H, Watada H, Hirose H, Tanaka Y, Tobe K, Kaku K, Kashiwagi A, Kawamori R, Maeda S
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 98(10) Issue: 10 Pages: E1667-E1673

    • DOI

      10.1210/jc.2013-1642

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591361, KAKENHI-PROJECT-24510276
  • [Journal Article] Replication study for the association of 9 East Asian GWAS-derived loci with susceptibility to type 2 diabetes in a Japanese population2013

    • Author(s)
      Sakai K, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S
    • Journal Title

      PLoS One

      Volume: 8 Issue: 9 Pages: e76317-e76317

    • DOI

      10.1371/journal.pone.0076317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591361, KAKENHI-PROJECT-24510276
  • [Journal Article] Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice.2013

    • Author(s)
      Fujisaka S, Usui I, Ikutani M, Aminuddin A, Takikawa A, Tsuneyama K, Mahmood A, Goda N, Nagai Y, Takatsu K, Tobe K.
    • Journal Title

      Diabetologia

      Volume: 56(6) Pages: 1403-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Journal Article] Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population2013

    • Author(s)
      Fukuda H, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.
    • Journal Title

      J Hum Genet

      Volume: 58 Issue: 7 Pages: 490-493

    • DOI

      10.1038/jhg.2013.28

    • NAID

      10031190046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591361, KAKENHI-PROJECT-24510276
  • [Journal Article] Replication study for the association of rs391300 in SRR and rs17584499 in PTPRD with susceptibility to type 2 diabetes in a Japanese population2013

    • Author(s)
      Imamura M, Iwata M, Maegawa H, Watada H, Hirose H, Tanaka Y, Tobe K, Kaku K, Kashiwagi A, Kadowaki T, Kawamori R and Maeda S
    • Journal Title

      J Diabetes Invest

      Volume: Volume 4 Issue 2 Issue: 2 Pages: 168-173

    • DOI

      10.1111/jdi.12017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591361, KAKENHI-PROJECT-24510276
  • [Journal Article] Genetic risk score constructed using 14 susceptibility alleles for type 2 diabetes is associated with the early onset of diabetes and may predict the future requirement of insulin injections among Japanese individuals2012

    • Author(s)
      Iwata M, Hara K, Kadowaki T
    • Journal Title

      Diabetes Care

      Volume: 35 Issue: 8 Pages: 1763-1770

    • DOI

      10.2337/dc11-2006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22591021, KAKENHI-PROJECT-24510276
  • [Journal Article] The Radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation2012

    • Author(s)
      Watanabe Y., Nakamura T., Ishikawa S., Fujisaka S., Usui I., Tsuneyama K., Ichihara Y., Wada T., Hirata Y., Suganami T., Izaki H., Akira S., Miyake K., Kanayama H., Shimabukuro M., Sata M., Sasaoka T.,Ogawa Y., Tobe K., Takatsu K., and Nagai Y.
    • Journal Title

      Diabetes.

      Volume: 61(5) Pages: 1199-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Journal Article] Tobe K. SRT1720, a SIRT1 activator pomotes tumor cell migration, and lung metasiasis of breast cancer in mice2012

    • Author(s)
      Suzuki K
    • Journal Title

      Oncol Rep

      Volume: 27 Pages: 1726-1732

    • DOI

      10.3892/or.2012.1750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590669, KAKENHI-PROJECT-22590971, KAKENHI-PROJECT-24659348
  • [Journal Article] The Radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation2012

    • Author(s)
      Y. Watanabe, T. Nakamura, S. Ishikawa, S. Fujisaka, I. Usui, K. Tsuneyama, Y. Ichihara, T. Wada, Y. Hirata, T. Suganami, H. Izaki, S. Akira, K. Miyake, H. Kanayama, M. Shimabukuro, M. Sata, T. Sasaoka, Y. Ogawa, K. Tobe, K. Takatsu, Y. Nagai
    • Journal Title

      Diabetes

      Volume: 61 Issue: 5 Pages: 1199-1209

    • DOI

      10.2337/db11-1182

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21117007, KAKENHI-PUBLICLY-22117509, KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-22590971, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-23659247, KAKENHI-PROJECT-23659420, KAKENHI-PROJECT-24659392, KAKENHI-PLANNED-21117002, KAKENHI-PUBLICLY-24117708
  • [Journal Article] A single nucleotide polymorphism within DUSP9 is associated with susceptibility to type 2 diabetes in a Japanese population.2012

    • Author(s)
      Hisashi Fukuda
    • Journal Title

      PLoS One

      Volume: 7 Issue: 9 Pages: e46263-e46263

    • DOI

      10.1371/journal.pone.0046263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591021, KAKENHI-PROJECT-23591361, KAKENHI-PROJECT-24510276
  • [Journal Article] The Radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation2012

    • Author(s)
      Watanabe Y., Nakamura T., Ishikawa S., Fujisaka S., Usui I., Tsuneyama K., Ichihara Y., Wada T., Hirata Y., Suganami T., Izaki H., Akira S., Miyake K., Kanayama H., Shimabukuro M., Sata M., Sasaoka T., Ogawa Y., Tobe K., Takatsu K., and Nagai Y
    • Journal Title

      Diabetes

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Journal Article] Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits2012

    • Author(s)
      Fujita H, Hara K, Kadowaki T
    • Journal Title

      J Hum Genet

      Volume: 57 Issue: 12 Pages: 776-779

    • DOI

      10.1038/jhg.2012.110

    • NAID

      10031145885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22790862, KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24510276
  • [Journal Article] Telmisartan improves insulin resistance and modulates adipose tissue macrophage polarization in high-fat-fed mice2011

    • Author(s)
      Fujisaka S, Usui I, Kanatani Y, Ikutani M, Takasaki I, Tsuneyama K, Tabuchi Y, Bukhari A, Yamazaki Y, Suzuki H, Senda S, Aminuddin A, Nagai Y, Takatsu K, Kobayashi M, Tobe K
    • Journal Title

      Endocrinology

      Volume: 152(5) Pages: 1789-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Journal Article] Deletion of platelet-derived growth factor receptor-βimproves diabetic nephropathy in Ca2+/calmodulin-dependent protein kinase IIα(Thr286 Asp) transgenic mice2011

    • Author(s)
      Suzuki H., Usui I., Kato I., Oya T., Kanatani Y., Yamazaki Y., Fujisaka S., Senda S., Ishii Y., Urakaze M., Mahmood A., Takasawa S., Okamoto H., Kobayashi M., Tobe K., Sasahara M
    • Journal Title

      Diabetologia

      Volume: 54 Pages: 2953-2962

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Journal Article] Telmisartan Improves Insulin Resistance and Modulates Adipose Tissue Macrophage Polarization in High-Fat-Fed Mice.2011

    • Author(s)
      Fujisaka S, Usui I, Kanatani Y, Ikutani M, Takasaki I, Tsuneyama K, Tabuchi Y, Bukhari A, Yamazaki Y, Suzuki H, Senda S, Aminuddin A, Nagai Y, Takatsu K, Kobayashi M, Tobe K.
    • Journal Title

      Endochnology

      Volume: 152(5) Pages: 1789-1799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Journal Article] Tranlocation of IRS-1 to Cytosol Attenuates Insulin-Stimulated Glucose Transport without Affecting PI3-Kinase Activity2010

    • Author(s)
      Junko Kawahara, Isao Usui, Tetsuro Haruta, Yukiko Kanatani, Kazuyuki Hiratani, Atsuko Takano, Tatsuhito Uno, Minoru Iwata, Masashi Kobayashi, Kazuyuki Tobe
    • Journal Title

      The Open Diabctcs Journal

      Volume: 3 Pages: 14-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Journal Article] Characterization of diabetic nephropathy in CaM kinase IIalpha(Thr286Asp) transgenic mice2009

    • Author(s)
      Suzuki H, Kato I, Usui I, Takasaki I, Tabuchi Y, Oya T, Tsuneyama K, Kawaguchi H, Hiraga K, Takasawa S, Okamoto H, Tobe K, Sasahara M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 379 Pages: 38-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Journal Article] Angiotensin II enhances the increase in monocyte chemoattractant protein-1 production induced by tumor necrosis factor-{ alpha} from 3T3-L1 preadipocytes2009

    • Author(s)
      Asamizu S, Urakaze M, Kobashi C, Ishiki M, Norel Din AK, Fujisaka S, Kanatani Y, Bukahari A, Senda S, Suzuki H, Yamazaki Y, Iwata M, Usui I, Yamazaki K, Ogawa H, Kobayashi M, Tobe K
    • Journal Title

      J Endocrinol

      Volume: 202 Pages: 199-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Journal Article] Inhibitory effect of IL-8 on insulin action in human adipocytes via MAP kinase pathway2009

    • Author(s)
      Kobashi C, Asamizu S, Ishiki M, Iwata M, Usui I, Yamazaki K, Tobe K, Kobayashi M, Urakaze M
    • Journal Title

      J Inflamm(Lond)

      Volume: 27 Pages: 6-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Journal Article] Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice2009

    • Author(s)
      Fujisaka S, Usui I, Bukhari A, Ikutani M, Oya T, Kanatani Y, Tsuneyama K, Nagai Y, Takatsu K, Urakaze M, Kobayashi M, Tobe K
    • Journal Title

      Diabetes

      Volume: 58 Pages: 2574-2582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Journal Article] Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice2009

    • Author(s)
      Yamazaki Y, Usui I, Kanatani Y, Matsuya Y, Tsuneyama K, Fujisaka S, Bukhari A, Suzuki H, Senda S, Imanishi S, Hirata K, Ishiki M, Hayashi R, Urakaze M, Nemoto H, Kobayashi M, Tobe K
    • Journal Title

      Am J Physiol Endocrinol Metab

      Volume: 297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Journal Article] SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta2008

    • Author(s)
      Oishi Y, Manabe I, Tobe K, Ohsugi M, Kubota T, Fujiu K, Maemura K, Kubota N, Kadowaki T, Nagai R.
    • Journal Title

      Nat Med. 14(6)

      Pages: 656-666

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019008
  • [Journal Article] In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue2008

    • Author(s)
      Nishimura S, Manabe I, Nagasaki M, Seo K, Yamashita H, Hosoya Y, Ohsugi M, Tobe K, Kadowaki T, Nagai R, Sugiura S.
    • Journal Title

      J Clin Invest 118(2)

      Pages: 710-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding2008

    • Author(s)
      Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T
    • Journal Title

      Cell Metab. 8(1)

      Pages: 49-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019008
  • [Journal Article] In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue2008

    • Author(s)
      Nishimura S, Manabe I, Nagasaki M, Seo K, Yamashita H, Hosoya Y, Ohsugi M, Tobe K, Kadowaki T, Nagai R, Sugiura S.
    • Journal Title

      J Clin Invest. 118(2)

      Pages: 710-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019008
  • [Journal Article] SUMOylation of Kruppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta2008

    • Author(s)
      Oishi Y, Manabe I, Tobe K, Ohsugi M, Kubota T, Fujiu K, Maemura K, Kubota N, Kadowaki T, Nagai R
    • Journal Title

      Nature Medicine 14

      Pages: 656-666

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019008
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim 56

      Pages: 149-154

    • NAID

      130000068045

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
    • Journal Title

      Cell Metab 6

      Pages: 55-68

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Glucokinase and IRS-2 are required for compensatory β cell hyperplasia in response to high-fat diet-induced insulin resistance.2007

    • Author(s)
      Terauchi Y, Takamoto I, Kubota N, Matsui J, Suzuki R, Komeda K, Hara A, toyoda Y, Miwa I, Aizawa S, Tsutsumi S, Tsubamoto Y, Hashimoto S, Eto K, Nakamura A, Noda M, Tobe K, Aburatani H, Nagai R, Kadowaki T.
    • Journal Title

      J Clin Invest. 117(1)

      Pages: 246-257

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Targeted disruption of AdipoRl and AdipoR2 causes abrogation of adiponectin binding and metabohc actions2007

    • Author(s)
      Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tbkuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
    • Journal Title

      Nat Med 13

      Pages: 332-339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M. Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim 56(2)

      Pages: 149-54

    • NAID

      130000068045

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007

    • Author(s)
      Hashmoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim 56

      Pages: 149-154

    • NAID

      130000068045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions2007

    • Author(s)
      Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y,Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
    • Journal Title

      Nat Med. 13(3)

      Pages: 332-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019008
  • [Journal Article] Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels2007

    • Author(s)
      Nishimura S, Manabe I, Nagasaki M, Hosoya Y, Yamashita H, Fujita H, Ohsugi M, Tobe K, Kadowaki T, Nagai R, Sugiura S.
    • Journal Title

      Diabetes 56(6)

      Pages: 1517-26

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalam us and increases food intake.2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y,
    • Journal Title

      Cell Metab. 6

      Pages: 55-68

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Targeted disruption of AdipoR1 and Adipo2 causes abrogation of adiponectin binding and metabolic actions.2007

    • Author(s)
      Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
    • Journal Title

      Nat Med. 13(3)

      Pages: 332-339

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
    • Journal Title

      Cell Metab. 6(1)

      Pages: 55-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019008
  • [Journal Article] Targeted disruption ofAdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions2007

    • Author(s)
      Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
    • Journal Title

      Nat Med. 13

      Pages: 322-339

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable.2007

    • Author(s)
      Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Exp Anim. 56

      Pages: 149-154

    • NAID

      130000068045

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007

    • Author(s)
      Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Mimokoshi Y, Ueki K,Minokoshi Y,Kadowaki T.
    • Journal Title

      CeU Metab 6

      Pages: 55-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
    • Journal Title

      J Biol Chem. 281(36)

      Pages: 26602-26614

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T
    • Journal Title

      J. Biol. Chem 281

      Pages: 26602-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Hepatocyte nuclear factor-4alpha P2 promoter haplotypes are associated with type 2 diabetes in the Japanese population2006

    • Author(s)
      Hara, K., Horikoshi, M., Kitazato, H., Ito, C., Noda, M., Ohashi, J., Froguel, P., Tokunaga, K., Tobe, K., Nagai, R., Kadowaki, T.
    • Journal Title

      Diabetes 55(5)

      Pages: 1260-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019008
  • [Journal Article] Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BLJ6J : Jcl mice deficient in insulin receptor substrate 22006

    • Author(s)
      Hashimoto H, Arai T, Takeguchi A, Hioki K, Ohnishi Y, Kawai K, Ito M, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    • Journal Title

      Comp Med 56(3)

      Pages: 176-87

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Journal Article] Adiponectin-dependent and independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006

    • Author(s)
      Kubota N, Yamauchi T, Tobe K, Kadowaki, T
    • Journal Title

      Diabetes 55 Suppl 2

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
    • Journal Title

      J Clin Invest. 116(7)

      Pages: 1784-1792

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006

    • Author(s)
      Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Is hikawa M, Moroi M, Sugi K, Ya mauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 8748-8755

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin-dependent and - independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinedions.2006

    • Author(s)
      Kubota N, Yamauchi T, Tobe K, Kadowaki T.
    • Journal Title

      Diabetes. 55 Suppl 2

    • Data Source
      KAKENHI-PROJECT-17390260
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
    • Journal Title

      J. Clin. Invest 116

      Pages: 1784-1792

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006

    • Author(s)
      Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
    • Journal Title

      J. Clin. Invest. 116

      Pages: 1784-1792

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Adiponectin-dependent and-independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones2006

    • Author(s)
      Kubota N, Yamauchi T, Tobe K, Kadowaki, T.
    • Journal Title

      Diabetes 55

      Pages: 32-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by-Both Adiponectin-dependent and-independent Pathways2006

    • Author(s)
      Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem 281

      Pages: 8748-8755

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem 281

      Pages: 26602-26614

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Tsunoda M, Id
    • Journal Title

      J. Bio1. Chem. 281

      Pages: 26602-26614

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209033
  • [Journal Article] Expression of DGAT2 in white adipose tissue is regulated by central leptin action.2005

    • Author(s)
      Suzuki R, Tobe K, Aoyama M, Sakamoto K, Ohsugi M, Kamei N, Nemoto S, Inoue A, Ito Y, Uchida S, Hara K, Yamauchi T, Kubota N, Terauchi Y, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 280

      Pages: 3331-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Kruppel-like transcription factor KLF5 is a key_regulator of adipocyte differentiation.2005

    • Author(s)
      Oishi Y, Manabe I, Tobe K, Tsushima K, Shindo T, Fujiu K, MD; Nishimura, Maemura K, Yamauchi T, Kubota N, Suzuki R, Kitamura T, Akira S, Kadowaki T, Nagai R.
    • Journal Title

      Cell Metabolism 1

      Pages: 27-39

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Insulin/Foxol pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity.2004

    • Author(s)
      Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, Kamon J, Kobayashi M, Suzuki R, Ham K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, Accili D, Tobe K, Ueki K, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 30817-30822

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] A novel IKK beta inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance.2004

    • Author(s)
      Kamon J, Yamauchi T, Muto S, Takekawa S, Ito Y, Hada Y, Ogawa W, Itai A, Kasuga M, Tobe K, Kadowaki T.
    • Journal Title

      Biochem. Biophys. Res. Commun. 323

      Pages: 242-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] SH2-containing inositol phosphatase 2 predominantly regulates akt2, and not akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes.2004

    • Author(s)
      Sasaoka T, Wada T, Fukui K, Murakami S, Ishihara H, Suzuki R, Tobe K, Kadowaki T, Kobayashi M.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 14835-14843

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Both insulin signaling defects in the liver and obesity contribute to insulin resistance and cause diabetes in IRS2-/- mice.2004

    • Author(s)
      Suzuki R, Tobe K, Aoyama M, Yamauchi T, Kamon J, Kubota N, Terauchi Y, Yoshimitsu H, Matsuhisa M, Nagasaka S, Ogata H, Tokuyama K, Nagai R, Kadowaki T.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 25039-25049

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Insulin receptor substrate-2 plays a crucial role in p cells and the hypothalamus.2004

    • Author(s)
      Kubota N, Terauchi Y, Tobe K, Yano W, Suzuki R, Ueki K, Takamoto I, Satoh H, Maki T, Kubota T, Moroi M, Okada-Iwabu M, Ezaki O, Naigi R, Ueta Y, Kadowaki T, Noda T.
    • Journal Title

      J. Clin. Invest 114

      Pages: 917-927

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Dual roles of adiponectin/Acrp30 in vivo as an anti-diabetic and anti-atherogenic adipokine.2003

    • Author(s)
      Yamauchi T, Hara K, Kubota N, Terauchi Y, Tobe K, Froguel P, Nagai R, Kadowaki T.
    • Journal Title

      Curr Drug Targets Immune Endocr Metabol Disord 3

      Pages: 243-254

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.2003

    • Author(s)
      Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Ham K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T.
    • Journal Title

      Nature 423

      Pages: 762-769

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Cytoskeletal reorganization induced by insulin : involvement of Grb2/Ash, Ras and phosphatidylinositol 3-kinase signaling.2003

    • Author(s)
      Tobe, K., et al.
    • Journal Title

      Genes Cells 8

      Pages: 29-40

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390284
  • [Journal Article] Molecular mechanism of insulin resistance and obesity.2003

    • Author(s)
      Kadowaki T, Hara K, Yamauchi T, Terauchi Y, Tobe K, Nagai R.
    • Journal Title

      Exp. Biol. Med. 228

      Pages: 1111-1117

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] The role of PPAR gamma in high-fat diet-induced obesity and insulin resistance.2002

    • Author(s)
      Kadowaki T, Hara K, Kubota N, Tobe K, Terauchi Y, Yamauchi T, Eto K, Kadowaki H, Noda M, Hagura R, Akanuma Y.
    • Journal Title

      J Diabetes Complications 16

      Pages: 41-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.2002

    • Author(s)
      Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, Yamauchi T, Otabe S, Okada T, Eto K, Kadowaki H, Hagura R, Akanuma Y, Yazaki Y, Nagai R, Taniyama M, Matsubara K, Yoda M, Nakano Y, Tomita M, Kimura S, Ito C, Froguel P, Kadowaki T.
    • Journal Title

      Diabetes 51

      Pages: 536-540

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Maturity-onset diabetes of the young resulting from a novel mutation in the HNF-4alpha gene.2002

    • Author(s)
      Hara K, Noda M, Waki H, Tobe K, Yamauchi T, Kadowaki H, Satou H, Tsukamoto K, Nagamatsu S, Yamagata K, Matsuzawa Y, Akanuma Y, Kimura S, Kadowaki T.
    • Journal Title

      Intern Med 41

      Pages: 848-852

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Froguel P. Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p.2002

    • Author(s)
      Mori Y, Otabe S, Dina C, Yasuda K, Populaire C, Lecoeur C, Vatin V, Durand E, Ham K, Okada T, Tobe K, Boutin P, Kadowaki T
    • Journal Title

      Diabetes 51

      Pages: 1247-1255

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes.2002

    • Author(s)
      Hara K, Tobe K, Okada T, Kadowaki H, Akanuma Y, Ito C, Kimura S, Kadowaki T.
    • Journal Title

      Diabetologia 45

      Pages: 740-743

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] Variants of neurogenin 3 gene are not associated with Type II diabetes in Japanese subjects.2001

    • Author(s)
      Okada T, Tobe K, Hara K, Yasuda K, Kawaguchi Y, Ikegami H, Ito C, Kadowaki T.
    • Journal Title

      Diabetologia 44

      Pages: 241-244

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Journal Article] The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.2001

    • Author(s)
      Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, AkanumaY, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T.
    • Journal Title

      Nature Medicine 7

      Pages: 941-946

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14013008
  • [Patent] Compositions and methods for the amelioration of Leptin resistance2004

    • Inventor(s)
      戸辺 一之, 鈴木 亮
    • Industrial Property Rights Holder
      戸辺 一之, 鈴木 亮
    • Filing Date
      2004-05-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390284
  • [Patent] Compositions and methods for the amelioration of leptin resistance2004

    • Inventor(s)
      戸部 一之, 鈴木 亮
    • Industrial Property Rights Holder
      戸部 一之, 鈴木 亮
    • Filing Date
      2004-05-28
    • Data Source
      KAKENHI-PROJECT-15390284
  • [Presentation] 脂肪組織常在性M2-like macrophageは肥満に伴って脂質関連マクロファージへと変化する.2022

    • Author(s)
      西村歩, 角朝信, Nawaz Allah, Bilal Muhammad, 桑野剛英, 渡邊善之, Rahil Aslam Muhammad, 五十嵐喜子, 藤坂志帆, 八木邦公, 戸邉一之.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] Isoxanthohumol improves obesity and insulin resistance through both pharmacological and gut microbial pathways.2022

    • Author(s)
      Watanabe Y, Fujisaka S, Watanabe S, Nawaz A, Kado T, Nishimura A, Bilal M, Rahil M, Morinaga Y, Tobe K.
    • Organizer
      IHMC 9th congress
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] イソキサントフモールは腸内細菌叢を通じて脂質吸収を抑制し, 抗肥満, 耐糖能改善作用を示す.2022

    • Author(s)
      渡邊善之, 藤坂志帆, 渡辺志朗, 桑野剛英, 西村歩, 角朝信, Muhammad Rahil Aslam, Muhammad Bilal, Allah Nawaz, 五十嵐喜子, 八木邦公, 戸邉一之.
    • Organizer
      第42回日本肥満学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] CD206+マクロファージの癌微小環境における役割.2022

    • Author(s)
      角朝信, 西村歩, Allah Nawaz, Bilal Muhammad, 桑野剛英, 渡邊善之, Rahil Aslam, 五十嵐喜子, 藤坂志帆, 八木邦公, 戸邉一之
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 腸内細菌を介した肥満症、インスリン抵抗性の新たな治療戦略.2022

    • Author(s)
      藤坂志帆,渡邊善之,戸邉一之
    • Organizer
      第43回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 腸内細菌を介した肥満症, インスリン抵抗性の新たな治療戦略.2022

    • Author(s)
      藤坂志帆, 渡邊善之, 戸邉一之.
    • Organizer
      第43回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] イソキサントフモールは腸内細菌の変化を介して宿主の小腸栄養トランスポーターを制御し抗肥満作用を発揮する.2022

    • Author(s)
      渡邊善之, 藤坂志帆, 桑野剛英, 西村歩, 角朝信, 五十嵐喜子, Rahil Muhammad Aslam, Bilal Muhammad, Nawaz Allah, 八木邦公, 渡辺志朗, 森永芳智, 戸邉一之.
    • Organizer
      第95回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] Isoxanthohumol improves obesity and insulin resistance through both pharmacological and gut microbial pathways.2022

    • Author(s)
      Watanabe Y, Fujisaka S, Watanabe S, Nawaz A, Kado T, Nishimura A, Bilal M, Rahil M, Morinaga Y, Tobe K
    • Organizer
      IHMC 9th congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] イソキサントフモールは腸内細菌の変化を介して宿主の小腸栄養トランスポーターを制御し抗肥満作用を発揮する.2022

    • Author(s)
      渡邊善之,藤坂志帆 桑野剛英,西村歩,角朝信,五十嵐喜子,Muhammad Aslam Rahil,Muhammad Bilal,Allah Nawaz, 八木邦公,渡辺志朗,森永芳智,戸邉一之
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 肥満における和漢薬や食品成分による腸内細菌叢を介したインスリン抵抗性改善作用.2022

    • Author(s)
      藤坂志帆, 戸邉一之.
    • Organizer
      第39回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] イソキサントフモールは腸内細菌の変化を介して宿主の小腸栄養トランスポーターを制御し抗肥満作用を発揮する.2022

    • Author(s)
      渡邊善之, 藤坂志帆, 桑野剛英, 西村歩, 角朝信, 五十嵐喜子, Muhammad Aslam Rahil, Muhammad Bilal, Allah Nawaz, 八木邦公, 渡辺志朗, 森永芳智, 戸邉一之.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 栄養素・薬剤によって構成される腸内細菌叢と宿主の代謝メカニズムに与える影響.2022

    • Author(s)
      渡邊善之, 藤坂志帆, 桑野剛英, 西村歩, 角朝信, 五十嵐喜子, Rahil Muhammad Aslam, Bilal Muhammad, Nawaz Allah, 八木邦公, 渡辺志朗, 森永芳智, 戸邉一之.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] イソキサントフモールは腸内細菌叢を通じて脂質吸収を抑制し、抗肥満、耐糖能改善作用を示す2022

    • Author(s)
      渡邊 善之、藤坂 志帆 、渡辺 志朗 、桑野 剛英 、西村 歩 、角 朝信、Muhammad Rahil Aslam、 Muhammad Bilal 、Allah Nawaz、五十嵐 喜子、八木 邦公 、戸邉一之
    • Organizer
      第43回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 企業健診における生活習慣を含む食事記録の解析と健診データと腸内細菌叢の関係性について2022

    • Author(s)
      朴木久恵,藤坂志帆,圓角麻子,渡邊善之,瀧川章子,八木邦公,中條大輔,奥牧人,戸邉一之
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 一般地域住民における糖尿病家族歴の種類による糖尿病発症リスクの相違についての検討.2022

    • Author(s)
      岩田実, 岡澤光代, 南茂, 樋口清博, 戸邉一之
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] イソキサントフモールは腸内細菌の変化を介して宿主の小腸栄養トランスポーターを制御し抗肥満作用を発揮する2022

    • Author(s)
      渡邊 善之,藤坂 志帆,桑野 剛英 ,西村 歩, 角 朝信,五十嵐 喜子, Rahil Muhammad Aslam, Bilal Muhammad, Nawaz Allah,八木 邦公,渡辺 志朗, 森永 芳智,戸邉 一之
    • Organizer
      第95回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 栄養素・薬剤によって構成される腸内細菌叢と宿主の代謝メカニズムに与える影響2022

    • Author(s)
      渡邊善之,藤坂志帆,桑野剛英,西村 歩,角 朝信,五十嵐喜子,Rahil Muhammad Aslam,Bilal Muhammad,Nawaz Allah,八木邦公,渡辺志朗,森永芳智,戸邉一之.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 肥満における和漢薬や食品成分による腸内細菌叢を介したインスリン抵抗性改善作用2022

    • Author(s)
      藤坂志帆、戸邉一之.
    • Organizer
      第39回和漢医薬学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] Role of adipose tissue-resident macrophages in the regulation of adipocyte and fibro-adipogenic progenitors.2022

    • Author(s)
      NAWAZ ALLAH, Bilal Muhammad, 角朝信, Aslam Muhammad Rahil, 五十嵐喜子, 西村歩, 渡邊善之, 桑野剛英, 岡部圭介, 八木邦公, 中川崇, 藤坂志帆, 戸邉一之.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] High-fat diet induces proliferation of adipocyte progenitors and hyperplasia in inguinal adipose tissue in male mice.2022

    • Author(s)
      Muhammad Bilal, Allah Nawaz, 角朝信, Muhammad Rahil Aslam, 桑野剛英, 西村歩, 渡邊善之, 五十嵐喜子, 八木邦公, 藤坂志帆, 中川崇, 戸邉一之.
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 高脂肪食負荷による脂肪組織常在性マクロファージの極性変化.2022

    • Author(s)
      西村歩, 角朝信, アラーナワズ, ムハンマド・ビラール, 桑野剛英, 渡辺善之, アスラム・ラヒール, 藤坂志帆, 八木邦公, 戸邉一之.
    • Organizer
      第42回日本肥満学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 肥満による脂肪組織常在性マクロファージの極性変化.2021

    • Author(s)
      西村 歩, 角 朝信, アラー ナワズ, ムハンマド ビラール, 桑野剛英, 渡辺善之, アスラム ラヒール, 劉 建輝, 藤坂志帆, 八木邦公, 生田宏一, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 日々の診療での気付きから新しい糖尿病学を切り拓く.2021

    • Author(s)
      戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 腸内細菌叢を介した脂質代謝が肥満、インスリン抵抗性に及ぼす影響.2021

    • Author(s)
      藤坂志帆, 戸邉一之.
    • Organizer
      第94回日本生化学大会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 巨大な解離性大動脈瘤を伴う巨細胞性動脈炎の一例.2021

    • Author(s)
      山崎美帆, 小野瀬崇文, 浅野諒子, 木戸敏喜, 津田玲奈, 朴木博幸, 篠田晃一郎, 戸邉一之.
    • Organizer
      第65回日本リウマチ学会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] EGFR遺伝子変異陽性肺癌の免疫チェックポイント阻害剤治療効果と患者背景及びCD68陽性細胞との関係.2021

    • Author(s)
      猪又峰彦, 津田岳志, 鈴木健介, 松本正大, 水島伊佐美, 勢藤善大, 徳井宏太郎, 高千紘, 岡澤成祐, 神原健太, 今西信悟, 三輪敏郎, 林龍二, 松井祥子, 正木康晶, 谷口浩和, 戸邉一之
    • Organizer
      第62会肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 富山県における糖尿病糖尿病および脂質異常症の調査結果.2021

    • Author(s)
      四方雅隆, 八木邦公, 山上孝司, 戸邉一之, 永田義毅.
    • Organizer
      第66回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 高脂肪食負荷により脂肪組織常在性マクロファージは脂質関連マクロファージへ変化する.2021

    • Author(s)
      西村 歩, 角 朝信, 渡邊善之, 桑野剛英, Muhammad Bilal, Muhammad Rahil Aslam, Allah Nawaz, 劉 建輝, 石本喜子, 藤坂志帆, 八木邦公, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] The role of CD206+ M2-like macrophages in tumor progrression.2021

    • Author(s)
      角 朝信, 西村 歩, Nawaz Allah, Muhammad Bilal, 桑野剛英, 渡辺善之, Muhammad Aslam Rahil, 劉 建輝, 藤坂志帆, 八木邦公, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 2型糖尿病の病態と治療戦略.2021

    • Author(s)
      戸邉一之.
    • Organizer
      日本内科学会北陸支部第83回生涯教育講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 腸内細菌叢が糖代謝に与えるインパクト2021

    • Author(s)
      藤坂志帆 戸邉一之
    • Organizer
      第41回日本肥満学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] EGFR遺伝子変異陽性例におけるPD-L1とPFS・T790M遺伝子変異検出割合との関連. (Association of tumor PD-L1 expression with the T790M mutation and progression-free survival in patients with EGFR-mutant non-small cell lung cancer receiving EGFR-TKI therapy.).2021

    • Author(s)
      猪又峰彦, 水島伊佐美, 畦地健司, 髙田巨樹, 林 加奈, 徳井宏太郎, 高 千紘, 岡澤成祐, 神原健太, 今西信悟, 三輪敏郎, 林 龍二, 松井祥子, 戸邉一之.
    • Organizer
      第61回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 脂肪組織におけるM1/M2マクロファージと前駆脂肪細胞の相互作用によるインスリン感受性の調節2021

    • Author(s)
      戸邉一之
    • Organizer
      第56回糖尿病学の進歩
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] Allergy in IgG4-related disease.2021

    • Author(s)
      Matsui S, Okazawa S, Tokui K, Kambara K, Imanishi S, Taka C, Inomata M, Komatsu M, Yamamoto H, Tobe K.
    • Organizer
      The 25th Congress of the Asian pacific Society of Respirology
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 腸内細菌叢が糖代謝に与えるインパクト2021

    • Author(s)
      藤坂 志帆, 戸邉 一之
    • Organizer
      第41回日本肥満学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 腸内細菌叢を介した脂質代謝が肥満、インスリン抵抗性に及ぼす影響2021

    • Author(s)
      藤坂志帆 戸邉一之
    • Organizer
      第94回日本生化学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] Fate of adipocyte progenitors during adipogenesis upon high fat diet feeding.2021

    • Author(s)
      Muhammad Bilal*, Allah Nawaz, 角 朝信, 五十嵐喜子, Muhammad Rahil Aslam, 渡邊善之, 西村 歩, 桑野剛英, 劉 建輝, 藤坂志帆, 八木邦公, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] Role of immune cells(macrophages) in recovery of muscle after injury.2021

    • Author(s)
      Allah Nawaz, 角 朝信, Muhammad Bilal, 五十嵐喜子, 岡部圭介, 渡邊善之, 西村 歩, 劉 建輝, 八木邦公, 藤坂志帆, 中川 崇, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 肺がん精査中の電解質異常を契機に診断された異所性ACTH症候群の一例.2021

    • Author(s)
      稲川慎哉, 瀧川章子, 松本正大, 横山茉貴, 朴木久恵, 水島伊佐美, 高 千紘, 神原健太, 八木邦公, 戸邉一之.
    • Organizer
      第20回日本内分泌学会北陸支部学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 肥満による発癌促進と免疫細胞の関連.2021

    • Author(s)
      角 朝信, 西村 歩, Allah Nawaz, Muhammad Bilal, 桑野剛英, 渡辺善之, Muhammad Rahil Aslam, 藤坂志帆, 八木邦公, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 富山県民のメタボリック症候群の生活習慣の実態調査.2021

    • Author(s)
      朴木久恵, 藤坂志帆, 上岸未樹, 横山茉貴, 四方雅隆, 圓角麻子, 瀧川章子, 中條大輔, 八木邦公, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 合同企画への期待.2021

    • Author(s)
      戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 脂肪組織におけるマクロファージ、前駆脂肪細胞およびベージュ脂肪細胞.2021

    • Author(s)
      桑野剛英, 五十嵐喜子, アラーナワズ, ムハンマド ラヒール アスラム, ムハンマド ビラール, 西村 歩, 渡辺善之, 角 朝信, 藤坂志帆, 八木邦公, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 栄養組成により確立した腸内細菌叢は、血中脂質プロファイルに大きな影響を与える2021

    • Author(s)
      渡邊 善之,藤坂 志帆,池田 和貴,山田 恭央,Allah Nawaz,角 朝信,Muhammad Bilal,西村 歩,桑野 剛英,劉 建輝,朴木 久恵,八木 邦公,長谷 耕二,戸邉 一之
    • Organizer
      第41回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] Malignancies concomitant with IgG4-related respiratory disease.2021

    • Author(s)
      Matsui S, Okazawa S, Tokui K, Azechi K, Takata N, Hayashi K, Taka C, Imanishi S, Kambara K, Inomata M, Tobe K.
    • Organizer
      American Thoracic Society 2021 International Conference
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 血中アミロイドA(SAA)は糖尿病腎症と関連する.2021

    • Author(s)
      岩田 実, 加村 裕, 朴木久恵, 石木 学, 八木邦公, 戸邉一之.
    • Organizer
      第65回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 関節リウマチに対するアバタセプト投与中の逆説性乾癬に対してトファシチニブが著効した2症例.2021

    • Author(s)
      篠田晃一郎, 朴木博幸, 津田玲奈, 山口智史, 松井 篤, 木戸敏喜, 浅野諒子, 川高正聖, 山崎美帆, 小野瀬崇文, 小檜山葵, 岡田幾磨, 戸邉一之.
    • Organizer
      第32回中部リウマチ学会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 防風通聖散投与中に腸内細菌Akkermansia muchiniphilaが増加した高度肥満症の一例2021

    • Author(s)
      藤坂志帆、朴木久恵、圓角麻子、山田眞之介、四方雅隆、瀧川章子、渡邊善之、角朝信、桑野剛英、西村歩、八木邦公、戸邉一之
    • Organizer
      第41回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] Role of adipose tissue-resident macrophages in the regulation of insulin sensitivity.2021

    • Author(s)
      Allah Nawaz, 角 朝信, Muhammad Bilal,Muhammad Rahil Aslam, 五十嵐喜子, 岡部圭介, 西田康宏, 渡邊善之, 西村 歩, 桑野剛英, 八木邦公, 中川 崇,藤坂志帆, 戸邉 一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 手術前後に75gOGTT て?経過を確認て?きたインスリノーマの一例.2021

    • Author(s)
      山田眞之介, 瀧川章子, 横山茉貴, 朴木久恵, 圓角麻子, 藤坂志帆, 中條大輔, 石木 学, 岩田 実, 八木邦公, 戸邉一之.
    • Organizer
      第95回日本糖尿病協会中部地方会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 腸内細菌叢への介入が及ぼす糖・脂質代謝への影響2021

    • Author(s)
      藤坂志帆 戸邉一之
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 当施設における抗MDA5抗体陽性皮膚筋炎患者の転帰にかかわる因子についての後ろ向き研究.2021

    • Author(s)
      木戸敏喜, 篠田晃一郎, 岡田幾磨, 小檜山葵, 小野瀬崇文, 川高正聖, 山崎美帆, 浅野諒子, 松井 篤, 山口智史, 津田玲奈, 朴木博幸, 戸邉一之.
    • Organizer
      第32回中部リウマチ学会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 栄養組成により確立した腸内細菌叢は、血中脂質プロファイルに大きな影響を与える2021

    • Author(s)
      渡邊善之 藤坂志帆 池田和貴 山田恭央 Allah Nawaz  角朝信 Muhammad Bilal 西村歩 桑野剛英 劉建輝 朴木久恵 八木邦公 長谷耕二 戸邉一之
    • Organizer
      第41回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 糖尿病における心筋拡張障害の予測指標としての心電図の断片化QRSの検討.2021

    • Author(s)
      八木邦公, 中條大輔, 上岸未樹, 横山茉貴, 四方雅隆, 圓角麻子, 瀧川章子, 朴木久恵, 藤坂志帆, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 多発性筋炎・皮膚筋炎:ケースプレゼンテーション 紅皮症で発症した抗SAE抗体陽性皮膚筋炎の一例.2021

    • Author(s)
      木戸敏喜, 篠田晃一郎, 四十万谷朱里, 川高正聖, 杉下尚徳, 浅野諒子, 津田玲奈, 朴木博幸, 戸邉一之.
    • Organizer
      第65回日本リウマチ学会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 2型糖尿病患者の入院治療において退院時インスリン治 療の要否を規定する因子の検討.2021

    • Author(s)
      上岸未樹, 中條大輔, 圓角麻子, 横山茉貴, 四方雅隆, 瀧川章子, 朴木久惠, 藤坂志帆, 八木邦公, 戸邉一之.
    • Organizer
      第65回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 過去に体重増加のあった非肥満2型糖尿病患者におけるインスリン必要性の検討.2021

    • Author(s)
      横山茉貴, 四方雅隆, 上岸未樹, 圓角麻子, 瀧川章子, 朴木久惠, 藤坂志帆, 中條大輔, 八木邦公, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] サイトメガロウイルス腸炎を契機に発症したIgA血管炎およびネフローゼ症候群の一例.2021

    • Author(s)
      小野瀬崇文, 朴木博幸, 岡田幾磨, 山崎美帆, 浅野諒子, 木戸敏喜, 津田玲奈, 篠田晃一郎, 戸邉一之.
    • Organizer
      第65回日本リウマチ学会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 2型糖尿病における入院治療による内因性インスリン分泌回復能に影響を与える因子の検討.2021

    • Author(s)
      圓角麻子*, 中條大輔, 上岸未樹, 横山茉貴, 四方雅隆, 瀧川章子, 朴木久恵, 藤坂志帆, 八木邦公, 戸邉一之.
    • Organizer
      第64回日本糖尿病年次学術集会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] SLEに二次性血栓性血小板減少性紫斑病を合併した1例.2021

    • Author(s)
      岡田幾磨, 朴木博幸, 小野瀬崇文, 山崎美帆, 浅野諒子, 木戸敏喜, 津田玲奈, 篠田晃一郎, 戸邉一之.
    • Organizer
      第65回日本リウマチ学会
    • Data Source
      KAKENHI-PROJECT-20H03730
  • [Presentation] 栄養組成による腸内細菌叢と糖代謝の相違2020

    • Author(s)
      藤坂 志帆,渡邊 善之,Allah Nawaz,角 朝信,Muhammad Bilal,西村 歩,桑野 剛英,劉 健輝,朴木 久恵,八木邦公,戸邉 一之
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-20K08882
  • [Presentation] 肥満・糖代謝異常における腸内細菌叢の意義2019

    • Author(s)
      藤坂 志帆 戸邉 一之
    • Organizer
      第24回アディポサイエンスシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 入院を契機に減量・代謝改善した高度肥満症の一例2019

    • Author(s)
      青山彩香、藤坂志帆、朴木久恵、圓角麻子、中川茉貴、瀧川章子、八木邦公、戸邉一之
    • Organizer
      第116回日本内科学会総会
    • Data Source
      KAKENHI-PROJECT-18K08505
  • [Presentation] 発症 24 年後にカベルゴリンを投与し血糖コントロールが良好となった末端肥大症の 1 例2018

    • Author(s)
      朴木久恵,岩田 実,上野麻子,渡邊善之,中嶋 歩,岡部圭介,角 朝信,瀧川章子,藤坂志帆,石木 学,八 木邦公,戸邉一之
    • Organizer
      第 91 回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08505
  • [Presentation] 腸内細菌叢と糖代謝異常2018

    • Author(s)
      藤坂 志帆, Kahn CR, 戸邉 一之.
    • Organizer
      第52回糖尿病学の進歩(シンポジウム)
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 手術加療を要した甲状腺機能亢進症5症例の心電図所見の検討.2018

    • Author(s)
      八木邦公,朴木久恵,圓角麻子,瀧川章子,稲川慎哉,桑野剛英,渡邊善之,西村 歩,角 朝信,岡部圭介,藤 坂志帆,石木 学,岩田 実,戸邉一之.
    • Organizer
      第28回 臨床内分泌代謝 Update
    • Data Source
      KAKENHI-PROJECT-18K08505
  • [Presentation] Bofutsushosan improved gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in diet-induced obese mice2018

    • Author(s)
      Shiho Fujisaka, Isao Usui, Allah Nawaz, Yoshiko Igarashi, Tomonobu Kado, Okabe Keisuke, Kunimasa Yagi, Takashi Nakagawa, Kazuyuki Tobe
    • Organizer
      78th Scientific Sessions of American Diabetes Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 腸内細菌叢と糖代謝異常2018

    • Author(s)
      藤坂 志帆、CR. Kahn、戸邉 一之
    • Organizer
      第52回糖尿病学の進歩
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 無症候性の褐色細胞腫の一例2018

    • Author(s)
      渡邊善之,佐野 功,大村佳之,上野麻子,中島 歩,角 朝信,岡部圭介,瀧川章子,藤坂志帆,朴木久恵,石 木 学,岩田 実,八木邦公,戸邉一之
    • Organizer
      第 91 回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08505
  • [Presentation] 腸内細菌叢、食事、遺伝背景による代謝産物の変化と糖代謝2018

    • Author(s)
      藤坂 志帆,Kahn CR,戸邉 一之
    • Organizer
      第36回内分泌代謝サマーセミナー
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 防風通聖散は腸内 細菌 Akkermansia muciniphila を増加させ、高脂肪食負荷マウスの糖代謝を改善する2018

    • Author(s)
      藤坂志帆,薄井 勲,ナワズアラー,五十嵐喜子,角 朝信,古澤之裕,八木邦公,戸邉一之
    • Organizer
      第 91 回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08505
  • [Presentation] 腸内細菌叢による代謝産物の劇的変化と糖代謝.2018

    • Author(s)
      藤坂 志帆,Kahn CR,戸邉 一之.
    • Organizer
      第23回アディポサイエンス・シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 腸内細菌叢を介した糖代謝制御2018

    • Author(s)
      藤坂 志帆、CR Kahn、戸邉 一之
    • Organizer
      日本薬学会第138年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 防風通聖散は腸内細菌Akkermansia muciniphilaを増加させ、高脂肪食負荷マウスの糖代謝を改善する2018

    • Author(s)
      藤坂 志帆、薄井 勲、Allah Nawaz、五十嵐 喜子、角 朝信、古澤 之裕、八木邦公、戸邉 一之
    • Organizer
      第91回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] MELAS3243 変異を有する糖尿病 7 症例の剖検臓器の変異率の検討.2018

    • Author(s)
      八木邦公,岡崎智子,大畠 梓,劉 建輝,朴木久恵,藤坂志帆,小堀健一,莇 也寸志,袖本幸男,戸邉一之.
    • Organizer
      第 91 回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08505
  • [Presentation] 腸内細菌叢を介した糖代謝制御2018

    • Author(s)
      藤坂 志帆, 戸邉 一之, Kahn CR.
    • Organizer
      日本薬学会第138年会(シンポジウム)
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] Depletion of CD206 M2 macophages promoters browning of white adipose tissue2018

    • Author(s)
      アラーナワズ,五十嵐喜子,角 朝信,瀧川章子,岡部圭介,藤坂志帆,中川 崇,八木邦公,戸邉一之
    • Organizer
      第 91 回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08505
  • [Presentation] Bofutsushosan, an Oriental Herbal Medicine, induces Akkermansia muciniphila and improves glucose metabolism in diet-induced obese mice.2017

    • Author(s)
      Shiho Fujisaka, Isao Usui, Yukihiro Furusawa, Allah Nawaz, Yoshiko Igarashi, Tomonobu Kado, Kazuyuki Tobe
    • Organizer
      77th Scientific Sessions of American Diabetes Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 腸内細菌叢の変化は血中代謝産物を劇的に変化させ耐糖能を制御する2017

    • Author(s)
      藤坂 志帆、Jonathan Dreyfuss、Clary Clish、Lynn Bry、戸邉 一之、C.Ronald Kahn
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 防風通聖散は腸内細菌Akkermansia muciniphilaを増加させ、高脂肪食負荷マウスの耐糖能を改善する2017

    • Author(s)
      藤坂 志帆、薄井 勲、古澤 之裕、Allah Nawaz、五十嵐 喜子、角 朝信、戸邉 一之
    • Organizer
      第22回日本肥満学会アディポサイエンス・シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] 腸内細菌叢が糖代謝に与える影響2017

    • Author(s)
      藤坂 志帆、C. Ronald Kahn、戸邉 一之
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09821
  • [Presentation] Myeloid cell-specific HIF-1α deletion decreases the number of liver tumors in high fat-fed mice.2016

    • Author(s)
      Takikawa A, Usui I, Zhang Q, Okabe K, Kado T, Nawaz A, Fujisaka S, Nakagawa T, Tsuneyama K, Tobe K.
    • Organizer
      76th Scientific Sessions of American Diabetes Association
    • Place of Presentation
      New Orleans
    • Year and Date
      2016-06-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] Nampt-mediated NAD synthesis regulates the differentiation of 3T3-L1 pre-adipocytes via poly(ADP-ribosyl)ation by PARPs.2016

    • Author(s)
      岡部圭介,薄井 勲,戸邉一之,中川 崇.
    • Organizer
      第21回アディポサイエンス・シンポジウム
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] Nampt-mediated NAD synthesis regulates the metabolic remodeling during the differentiation of 3T3-L1 pre-adipocytes.2016

    • Author(s)
      Okabe K, Usui I, Tobe K, Nakagawa T.
    • Organizer
      76th Scientific Sessions of American Diabetes Association
    • Place of Presentation
      New Orleans
    • Year and Date
      2016-06-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] 肥満症・糖尿病での肝がん発症におけるマクロファージHIF-1αの働き.2016

    • Author(s)
      3) 瀧川章子,薄井 勲,張 群,岡部圭介,角 朝信,Allah Nawaz,藤坂志帆,常山幸一,戸邉一之.
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] 2型糖尿病患者の内因性インスリン分泌評価指標に及ぼす腎機能の影響.2016

    • Author(s)
      4) 岡部圭介,岩田 実,渡邊善之,中嶋 歩,角 朝信,瀧川章子,朴木久恵,小清水由紀子,石木 学,薄井 勲,戸邉一之.
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] マクロファージ特異的HIF-1α欠損による食餌性肥満マウスの糖代謝・脂肪組織への影響.2016

    • Author(s)
      8) 瀧川章子,Arshad Mahmood,Allah Nawaz,岡部圭介,角 朝信,中川 崇,藤坂志帆,薄井 勲,戸邉一之.
    • Organizer
      第37回日本肥満学会
    • Place of Presentation
      東京
    • Year and Date
      2016-10-07
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] 肥満症・糖尿病での肝がん発症におけるマクロファージHIF-1αの働き.2016

    • Author(s)
      瀧川章子,薄井 勲,張 群,岡部圭介,角 朝信,Allah Nawaz,藤坂志帆,常山幸一,戸邉一之.
    • Organizer
      第34回内分泌代謝学サマーセミナー
    • Place of Presentation
      久山
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] The effect of renal function on β-cell function related parameters in Japanese type 2 diabetic patients.2015

    • Author(s)
      Okabe K, Iwata M, Nakashima A, Shinmura S, Kado T, Wakura T, Takikawa A, Koshimizu Y, Hounoki H, Ishiki M, Fukuda K, Usui I, Tobe K.
    • Organizer
      75th scientific sessions of American Diabetes Association
    • Place of Presentation
      Boston
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] 老化のサイエンスSirtuin研究の深化と展望マクロファージSIRT1による糖代謝制御.2015

    • Author(s)
      薄井 勲,瀧川章子,戸邉一之.
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      下関市
    • Year and Date
      2015-05-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] Myeloid cell-specific HIF-1 alpha deletion protected against insulin resistance with increased angiogenesis in high fat-fed mice.2015

    • Author(s)
      Takikawa A, Mahmood A, Nawaz A, Kado T, Senda S, Okabe K, Usui I, Tobe K.
    • Organizer
      75th scientific sessions of American Diabetes Association
    • Place of Presentation
      Boston
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] マクロファージ特異的HIF-1α欠損は高脂肪食負荷マウスの糖代謝を改善する.2015

    • Author(s)
      瀧川章子,Arshad Mahmood,Allah Nawaz,角 朝信,仙田聡子,薄井 勲,合田亘人,戸邉一之.
    • Organizer
      第88回日本内分泌学会学術総会
    • Place of Presentation
      東京都
    • Year and Date
      2015-04-23
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] 肥満における臓器障害-肥満における脂肪組織マクロファージの機能.2015

    • Author(s)
      薄井 勲,瀧川章子,戸邉一之.
    • Organizer
      第36回日本肥満学会
    • Place of Presentation
      名古屋市
    • Year and Date
      2015-10-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] マクロファージ特異的HIF-1α欠損は高脂肪食負荷マウスの糖代謝を改善する2014

    • Author(s)
      瀧川章子,Mahmood A,仙田聡子,薄井勲,戸邉一之
    • Organizer
      日本肥満学会第19回アディポサイエンス・シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2014-08-23
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] マクロファージ特異的HIF-1α欠損は高脂肪食負荷マウスの糖代謝を改善する2014

    • Author(s)
      瀧川章子,Mahmood A,藤坂志帆,仙田聡子,Aminuddin,中川崇,薄井勲,戸邉一之
    • Organizer
      第51回日本臨床分子医学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-11
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] 脂肪組織低酸素とインスリン抵抗性2013

    • Author(s)
      薄井勲、藤坂志帆、瀧川章子、Arshad Mahmood、戸邉一之
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Year and Date
      2013-05-17
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] Comparison of clinical usefulness between type 2 diabetes genetic risk score and family history in Japanese type 2 diabetic patients.2013

    • Author(s)
      Iwata M., Maeda S., Kamura Y., Takano A., Kato H., Murakami S., Higuchi K., Temaru R., Asamizu S., Oda H., Fukushima Y., and Tobe K.
    • Organizer
      14th International Diabetes Federation
    • Place of Presentation
      Melbourne
    • Data Source
      KAKENHI-PROJECT-24510276
  • [Presentation] Genetic risk scoreと糖尿病家族歴の情報から成るfamily history scoreの糖尿病臨床像との関連性における比較検討2013

    • Author(s)
      岩田 実,前田士郎,加村 裕,高野敦子,村上史峰,加藤弘巳,福島泰男,手丸理恵,赤川直次,樋口清博,薄井 勲,石木 学,小橋親晃,山崎勝也,浦風雅春,浅水幸恵,井窪万里子,小田寛文,五十嵐保文,多喜和子,福田一仁,戸辺一之
    • Organizer
      第56回日本糖尿病学会年次学術集会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24510276
  • [Presentation] Type 2 diabetes genetic risk score is more strongly associated with basal insulin secretion and insulin requirement than family history in Japanese type 2 diabetic patients.2013

    • Author(s)
      Iwata M., Maeda S., Kamura Y., Takano A., Kato H., Murakami S., Higuchi K., Temaru R., Oda H., Asamizu S., Fukushima Y., Fukuda K., Yamazaki K., Usui ., and Tobe K.
    • Organizer
      49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes
    • Place of Presentation
      Barcelona
    • Data Source
      KAKENHI-PROJECT-24510276
  • [Presentation] 慢性炎症とインスリン抵抗性 脂肪組織マクロファージとSIRT1 (シンポジウム)2012

    • Author(s)
      薄井 勲,藤坂志帆,瀧川章子,金谷由紀子,戸邉一之
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] Impact of Adipose Tissue Hypoxia on Macriphage Polarization in Diet-induced Obese Mice2012

    • Author(s)
      Fujisaka S., Usui I., Ikutani M., Aminuddin A., Senda S., Takikawa A., Ishiki M., Koshimizu Y., Tsuneyama K., Nagai Y., Takatsu K., Tobe K.
    • Organizer
      American Diabetes Association 72nd Scientific Sessions
    • Place of Presentation
      Philadelphia(USA)
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] Astaxanthin, a Strong Antioxidant, Regulates Insulin Signaling by Various Mechanisms In Vivo2012

    • Author(s)
      Ishiki M., Nishida Y., Fujisaka S., Usui I., Tobe K.
    • Organizer
      American Diabetes Association 72nd Scientific Sessions
    • Place of Presentation
      Philadelphia(USA)
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] 遺伝的リスクスコア(Genetic risk score)は糖尿病診断時年齢やインスリン分泌能と関連する2012

    • Author(s)
      岩田 実,前田 士郎, 加村 裕, 高野 敦子, 手丸 理恵, 加藤 弘巳, 赤川 直次, 村上 史峰, 樋口 清博, 戸辺 一之
    • Organizer
      第109回日本内科学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24510276
  • [Presentation] 慢性炎症とインスリン抵抗性 脂肪組織マクロファージとSIRT1(シンポジウム)2012

    • Author(s)
      薄井勲,藤坂志帆,瀧川章子,金谷由紀子,戸邉一之
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2012-05-17
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] Myeloid Cell-specific Deletion of SIRT1 Impairs Glucose Metabolism wiht Enhanced Inflammatory Response to Hypoxia2012

    • Author(s)
      Takikawa A., Usui I., Senda S., Fujisaka S., Hattori S., Tsuneyama K., Aminuddin A., Mahmood A., Sasaoka T., Mori H., Tobe K.
    • Organizer
      American Diabetes Association 72nd Scientific Sessions
    • Place of Presentation
      Philadelphia(USA)
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] インスリン抵抗性のメカニズムと新しい治療戦略脂肪組織マクロファージとインスリン抵抗性。(シンポジウム)2011

    • Author(s)
      薄井勲、藤坂志帆、瀧川章子、仙田聡子、小清水由紀子、戸邉一之
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] Obesity-induced hypoxia regulates the polarization of adipose tissuee macrophages2011

    • Author(s)
      Fujisaka S., Usui I., Ikutani M., Kanatani Y, Senda S., Takikawa A., Aminuddin A., Suzuki H., Ishiki M., Iwata M., Nagai Y., Takatsu K., Tobe K.
    • Organizer
      American Diabetes Association 71^<th> Scientific Sessions
    • Place of Presentation
      San Diego
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] Astaxanthin, a strong antioxidant, possesses various effects on insulin signaling in vitro2011

    • Author(s)
      Ishiki M., Nishida Y., Ishibashi H., Koshimizu Y., Fujisaka S., Usui I., Tobe K.
    • Organizer
      American Diabetes Association 71^<th> Scientific Sessions
    • Place of Presentation
      San Diego
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] 低酸素環境に対するM1/M2マクロファージの反応性に関する検討2011

    • Author(s)
      藤坂志帆,薄井勲,生谷尚士,仙田聡子,瀧川章子,AminuddinAminuddin,金谷由紀子,長井良憲,石木学,戸邉一之
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] 肥満脂肪組織の低酸素がマクロファージの極性に与える影響。(シンポジウム)2011

    • Author(s)
      薄井勲、戸邉一之
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] Hyperleptinemia induces leptin resistancce and further worsening obesity2011

    • Author(s)
      Senda S., Inoue A., Suzuki R., Kamei N., Watanabe T., Mahmood A., Takikawa A., Aminuddin A., Fujisaka S., Koshimizu Y., Ishiki M., Usui I., Kadowaki T., Tobe K.
    • Organizer
      American Diabetes Association 71^<th> Scientific Sessions
    • Place of Presentation
      San Diego
    • Year and Date
      2011-06-26
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] The Effect of SRT1720 on Infalammation and Oxidative Stress in White Adipose Tissue of High Fat-fed Mice2010

    • Author(s)
      Yukiko Kanatani, Isao Usui, Shiho Fujisaka, Yuji Matsuya, Satoko Senda, Akiko Takikawa, Aminuddin, Masaharu Urakaze, Kazuyuki Tobe
    • Organizer
      American Diabetes Association 70^<th> scientific sessions
    • Place of Presentation
      Orlando
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] PDGFR-β deletion improves diabetic nephropathy in CaM Kinase IIα (Thr286Asp) Transgenic Mice.2010

    • Author(s)
      Suzuki H., Usui I., Kato I., Kanatani Y., Yamazaki Y., Fujisaka S., Senda S., Urakaze M., Sasahara M., Takasawa S., Okamoto H., Kobayashi M., Tobe K.
    • Organizer
      The 70th American Diabetes Association Scientific Sessions
    • Place of Presentation
      Orlando
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] Activation of interleukin-10 signaling in hypothalamus decreases body weight and improves insulin sensitivity without affecting food intake.2010

    • Author(s)
      Isao Usui, Shiho Fujisaka, Yukiko Kanatani, Agussalim Bukhali, Satoko Senda, Aminuddin, Kazuyuki Tobe
    • Organizer
      The 70th American Diabetes Association Scientific Sessions
    • Place of Presentation
      Orlando
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] SIRT1の活性化が肥満マウスの白色脂肪組織の炎症と酸化ストレスに与える影響2010

    • Author(s)
      金谷由紀子、薄井勲、藤坂志帆、山崎夕、瀧川章子、鈴木ひかり、仙田聡子、Aminuddin石木学、浦風雅春、戸邉一之
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] 脂肪組織M1/M2マクロファージとインヌリン抵抗性の関連について2010

    • Author(s)
      藤坂志帆, 薄井勲, アグッサリムブクハリ, 生谷尚士, 金谷由紀子, 山崎夕, 鈴木ひかり, 仙田聡子, 石木学, アミヌディン, 瀧川章子, 浦風雅春, 小林正, 戸辺一之
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] 脂肪組織M1/M2マクロファージとインスリン抵抗性の関連について2010

    • Author(s)
      藤坂志帆, 薄井勲, アグッサリムブクハリ, 生谷尚士, 金谷由紀子, 山崎夕, 鈴木ひかり, 仙田聡子, 石木学, アミヌディン, 瀧川章子, 浦風雅春, 小林正, 戸邉一之
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-21591126
  • [Presentation] Regulation of body weight and insulin sensitivity by hypothalamic activation of interleukin-10 signaling(シンポジウム)2010

    • Author(s)
      Isao Usui, Shiho Fujisaka, Yukiko Kanatani, Agussalim Bukhari, Satoko Senda, Aminuddin, Kazuyuki Tobe
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-22590971
  • [Presentation] Exocytosis Complex Molecules Rab3 and SNAP25 in Islet β cells in Response to Systemic Insulin Resistance and Glucotoxicity2007

    • Author(s)
      Kobayashi M, Tobe K, Suzuki R, Ohsugi M, Kowatari-Otsuka N, Sakamoto K Kubota N, Terauchi Y, Nagamatsu S, and Kadowaki T
    • Organizer
      49th Annual Scientific Meeting of the Japan Diabetes Society
    • Place of Presentation
      Tokyo, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] Critical Roles of IRS-1 and IRS-2 in the Development of Fetal Pancreatic Islets2007

    • Author(s)
      Ohsugi M, Tobe K, Suzuki R, Kowatari-Otsuka N, Kubota N, Terauchi Y, and 10th Annual Kadowaki T
    • Organizer
      Scientific Meeting of Japan Society of Metabolism and Clinical Nutrition
    • Place of Presentation
      Yokohama, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] Mice Overexpressing Monocyte Chemoattract Protein 1(MCP-1) in Adipose Tissues Exhibit Insulin Resistance in the Skeltal Muscle2007

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Sakamoto K, Kobayashi M, Kowatari-Otsuka N, Kubota N, and Kadowaki T.
    • Organizer
      49th Annual Scientific Meeting of the Japan Diabetes Society
    • Place of Presentation
      Tokyo, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] Islet IRS-2 Increases in Response to Systemic Insulin Resistance2007

    • Author(s)
      Ohsugi M, Tobe K, Kobayashi M, Suzuki R, Sasako T, and Kadowaki T
    • Organizer
      50th Annual Scientific Meeting of the Japan Diabetes Society
    • Place of Presentation
      Sendai, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] Mice Overexpressing Monocyte Chemoattract Protein 1(MCP-1) in Adipose Tissues Exhibit Whole Body Insulin Resistance2006

    • Author(s)
      Kamei N, Tobe K, Suzuki R, Ohsugi M, Kubota N, and Kadowaki T.
    • Organizer
      American Diabetes Association Annual Scientific Sessions, Washington DC
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590978
  • [Presentation] Myeloid-Specific deletion of Hypoxia-inducible factor 1-alpha gene protected against Diet induced Insulin resistance

    • Author(s)
      Mahmood A, Senda S, Nakagawa T, Fujisaka S, Takikawa A, Aminuddin A, Nawaz A, Usui I, Tobe K.
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] Astaxanthin, a strong antioxidant, ameliorated glucose metabolism in obese mouse through various mechanisms

    • Author(s)
      IshikiM, NishidaY, TakikawaA, KoshimizuY, IwataM, UsuiI, TobeK.
    • Organizer
      74th scientific sessions of American Diabetes Association
    • Place of Presentation
      San Francisco
    • Year and Date
      2014-06-13 – 2014-06-17
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] マクロファージ特異的HIF-1α欠損は高脂肪食負荷マウスの糖代謝を改善する

    • Author(s)
      瀧川章子,Mahmood A,薄井勲,戸邉一之
    • Organizer
      日本内分泌学会第32回内分泌代謝学サマーセミナー
    • Place of Presentation
      山梨
    • Year and Date
      2014-07-10 – 2014-07-12
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] Depletion of CD206-positive cells is associated with increased white adipose tissue proliferation

    • Author(s)
      Aminuddin, Takikawa A, Usui I, Fujisaka S, Mahmood A, Nawaz A, Tobe K.
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] 欧米人集団ゲノムワイド関連解析で同定された2型糖尿病感受性遺伝子領域の日本人集団における検証

    • Author(s)
      酒井 健輔, 今村 美菜子, 岩田 実, 広瀬 寛, 綿田 裕孝, 前川 聡, 戸辺 一之, 柏木 厚典, 加来 浩平, 河盛 隆造, 田中 逸, 前田 士郎
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-24510276
  • [Presentation] マクロファージ特異的HIF-1 alpha欠損は高脂肪食負荷マウスの糖代謝を改善する

    • Author(s)
      瀧川章子,Mahmood A,Nawaz A,角朝信,薄井勲,戸邉一之
    • Organizer
      第29回日本糖尿病・肥満動物学会
    • Place of Presentation
      京都
    • Year and Date
      2015-02-13 – 2015-02-14
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] Myeloid cell-specific deletion of hypoxia-inducible factor 1-alpha gene protected against diet-induced insulin resistance in mice

    • Author(s)
      Takikawa A, Mahmood A, Fujisaka S, Nakagawa T, Senda S, Aminuddin A, Usui I, Tobe K.
    • Organizer
      74th scientific sessions of American Diabetes Association
    • Place of Presentation
      San Francisco
    • Year and Date
      2014-06-13 – 2014-06-17
    • Data Source
      KAKENHI-PROJECT-26461327
  • [Presentation] 脂肪組織の慢性炎症における低酸素とマクロファージの関連

    • Author(s)
      瀧川章子,薄井勲,藤坂志帆,Mahmood A,仙田聡子,Aminuddin,岡部圭介,角朝信,小清水由紀子,戸邉一之.
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26461327
  • 1.  KADOWAKI Takashi (30185889)
    # of Collaborated Projects: 34 results
    # of Collaborated Products: 49 results
  • 2.  YAMAUCHI Toshimasa (40372370)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 32 results
  • 3.  TERAUCHI Yasuo (40359609)
    # of Collaborated Projects: 15 results
    # of Collaborated Products: 1 results
  • 4.  HARA Kazuo (50359600)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 18 results
  • 5.  KABURAGI Yasushi
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 6.  SEKO Yoshinori (30240708)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 7.  UEKI Kohjiro (00396714)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 11 results
  • 8.  KUBOTA Naoto (50396719)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 27 results
  • 9.  TAMAMOTO Hiroyuki
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 10.  ETO Kazuhiro
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 11.  FUJISAKA Shiho (30512082)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 46 results
  • 12.  HONDA Ritsuko
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 13.  YASUDA Kazuki
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 14.  NAGAI Ryozo (60207975)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 15.  USUI Isao (50377272)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 34 results
  • 16.  瀧川 章子 (80647454)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 31 results
  • 17.  KONO Shinjiro (40333463)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  SUZUKI Ryo (20396732)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  NODA Mitsuhiko (90237850)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  Yagi Kunimasa (30293343)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 18 results
  • 21.  東 成一 (70313137)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  ENOKAWA Yoshifumi
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  高橋 直之
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  MORITA Hiroyuki (60323573)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KOSHIMIZU Yukiko (30511828)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 26.  SHINODA Kouichirou (40377312)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  MINOKOSHI Yasuhiko (10200099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  IWATA MINORU (20345565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 29.  MAEDA Shiro (50314159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 30.  YAMADA Toru (40512091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  KODAMA Tatsuhiko (90170266)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  NAKAMURA Kozo (60126133)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  KAWAGUCHI Hiroshi (40282660)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  YOSUYUKI Ohnishi (70201382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  HASHIMOTO Haruo (30353478)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  HIOKI Kyoji (80208735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  AMI Toshiro (70184257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  MITSURU Ohsugi (00420216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 39.  Honoki Hisae (40772330)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  Chujo Daisuke (30640528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  山崎 力 (60251245)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  林 龍二 (60345585)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  佐倉 宏 (70240710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  小崎 慶介 (60302692)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  角 朝信 (40779021)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 26 results
  • 46.  中川 嘉 (80361351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  島野 仁 (20251241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  長谷 耕二 (20359714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  樋上 賀一 (90253640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  生田 宏一 (90193177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  佐武 利彦 (60271318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  武藤 真由 (10723348)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  三上 太郎 (90315804)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  KAMURA Yutaka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 55.  NAKAGAWA Hajime
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  TAKANO Atsuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 57.  KATO Hiromi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 58.  TEMARU Rie
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 59.  FUKUSHIMA Yasuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 60.  HIGUCHI Kiyohiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 61.  TAKI Kazuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 62.  IGARASHI Yasuhumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 63.  SAWASAKI Shigeki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 64.  KANGAWA Kenji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  山下 滋雄
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 66.  高橋 倫子
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 67.  森 保道
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 68.  小林 篤樹
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 69.  NAGAI Yoshinori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 70.  SHOJIMA Nobuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 71.  IKUTANI Masashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 72.  HONDA Hiroe
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 73.  今村 美菜子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 74.  柳橋 努
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 75.  中川 崇
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 76.  小川 佳宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 77.  佐田 政隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 78.  仙田 聡子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 79.  常山 幸一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 80.  NAWAZ ALLAH
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 81.  高津 聖志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 82.  山本 誠士
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 83.  笹原 正清
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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