Mukai Takahiro 向高弘

… Alternative Names

MUKAI Takahiro 向高弘

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Researcher Number	30284706
Other IDs
Affiliation (Current)	2025: 神戸薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2011 – 2024: 神戸薬科大学, 薬学部, 教授 2007 – 2010: Kyushu University, 大学院・薬学研究院, 准教授 2007: 九州大学, 大学院・薬学研究院, 準教授 2006: 九州大学, 大学院・薬学研究院, 助教授 2005 – 2006: 九州大学, 大学院薬学研究院, 助教授 … More 2003 – 2006: 九州大学, 薬学研究院, 助教授 2004: 九州大学, 大学院・薬学研究院, 助教授 2004: KYUSYU UNIVERSITY, PHARMACOLOGY, Associate Professor, 薬学研究院, 助教授 1999 – 2004: 京都大学, 医学研究科, 助手 1999: 京都大学, 大学院・医学研究科, 助手 1998: 長崎大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Radiation science / Biological Sciences / Basic Section 52040:Radiological sciences-related / Medium-sized Section 52:General internal medicine and related fields / Pain science / Radiation science / 医薬分子機能学 Except Principal Investigator Radiation science / Physical pharmacy / Physical pharmacy / Radiation science / 医薬分子機能学
Keywords	Principal Investigator 薬学 / 放射線 / イメージング / 癌 / レニウム / 放射性薬剤 / 骨転移 / 腫瘍 / 放射性医薬品 / 内用放射線治療 … More / ビスホスホネート / ガリウム / がん / 核医学診断 / 自己組織化ナノ粒子 / がん治療 / セラノスティクス / 活性酸素 / 蛍光 / ナノ材料 / ヘパラナーゼ / 蛍光色素 / アミロイド / ナノバイオ / 受容体 / 痛み / 分子イメージング / 疼痛 / 造影剤 / キレート / PET / 腫傷 / 疼痛治療 / ビスホスフォネート / 胆汁排泄 / リソソーム / 放射性代謝物 / 肝臓 / 放射能 / 蛋白質 … More Except Principal Investigator nAChR / SPECT / 5IA / Drug delivery system / Rat / Liver surface application / Drug targeting / Liver / CMC / DDS / ラット / 肝臓表面投与 / 薬物送達 / 肝臓 / 腫瘍 / インビボイメージング / radiolabeled molecular probe / macrophage / lectine-like oxidized LDL receptor / glucose derivative / radiation detector / molecular imaging / vulnerable plaque / thrombosis / F-18 / LOX-1 / 超小型放射線検出器 / 放射性プローブ / マクロファージ / スカベンジャー受容体 / グルコース誘導体 / 放射線検出器 / 分子イメージング / 不安定プラーク / 血栓 / fluorinated thymidine derivative / positron emission tomography / evaluation of treatment effect / evaluation of malignant potential / brain tumor / フッ素標識チミジン誘導体 / ポジトロン断層法 / 治療効果判定 / 悪性度診断 / 脳腫瘍 / acetylcholine receptor / smoking / quantitative / nicotine / 動脈血採血 / 定量解析 / dynamic収集 / アセチルコリン受容体 / 分布容積 / 禁煙 / 受容体 / ニコチン / 喫煙 / 定量 / ニコチン受容体 / Cancer chemotherapy / Anticancer agent / 5-Fluorouracil / 抗癌剤 / 癌化学療法 / 制癌剤 / 5-fluorouracil / radiopharmaceutical / tumor / Radioiodine / Rhodacyanine derivative / lipophilic cation / membrane potentia / mitochondria / 脂溶性カオチン / ログシアニン誘導体 / 核医学診断薬 / 放射性ヨウ素 / ロダシアニン誘導体 / 脂溶性カチオン / 膜電位 / ミトコンドリア / Viscous dosage form / Phenol red / 微量連続投与 / 単回投与 / 粘性製剤 / phenol red / 合成法 / がん / ヨウ素原子 / 合成性 / テロメラーゼ / 内用放射線治療 / ガン / 変異型ドパミンレセプター / レポータ遺伝子 / インターロイキン-10 / 免疫抑制遺伝子治療 / 心臓移植 / 遺伝子イメージング / シクロオキシゲナーゼ / チミジン / プロスタグランジン / 核酸合成 / 鑑別診断 / 炎症 / ヒドロキシアパタイト / 体内動態 / 二官能性キレート / 細胞致死作用 / 放射線 / 放射性レニウム / ビスホスフォネート / 骨疼痛緩和 Less

外部刺激に応答するがん標的セラノスティックナノデバイスの開発Principal Investigator
- Principal Investigator
  
  向高弘
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kobe Pharmaceutical University
Development of radiolabeled probes enabling to detect reactive oxygen species separately in living bodyPrincipal Investigator
- Principal Investigator
  
  Mukai Takahiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kobe Pharmaceutical University
Development of a tri-functional chelate for nuclear/fluorescence dual imagingPrincipal Investigator
- Principal Investigator
  
  Mukai Takahiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Kobe Pharmaceutical University
Development of self-assembled nanodevices for cancer-targeted radiotheranosticsPrincipal Investigator
- Principal Investigator
  
  Mukai Takahiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kobe Pharmaceutical University
Development of a radioiodine-labeled heparanase-targeted probePrincipal Investigator
- Principal Investigator
  
  Mukai Takahiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kobe Pharmaceutical University
Development of radiolabeled probes for molecular imaging of AA amyloidosisPrincipal Investigator
- Principal Investigator
  
  MUKAI Takahiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kobe Pharmaceutical University
Development of self-assembling nanodevices for multimodal molecular imagingPrincipal Investigator
- Principal Investigator
  
  MUKAI Takahiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kobe Pharmaceutical University
Development of a high spec multivalent PET probe for molecular imaging of painPrincipal Investigator
- Principal Investigator
  
  MUKAI Takahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pain science
- Research Institution
  Kobe Pharmaceutical University
Development of radiogallium-labeled agents for PET imaging without cyclotronPrincipal Investigator
- Principal Investigator
  
  MUKAI Takahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kobe Pharmaceutical University
  Kyushu University
がんの物理療法としての分子標的型内用放射線治療法の確立Principal Investigator
- Principal Investigator
  
  向高弘
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
放射線により発現誘導される酵素を標的とする相乗的内用放射線治療法への挑戦Principal Investigator
- Principal Investigator
  
  向高弘
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyushu University
内用放射線がん治療法の確立を目的とした二官能性放射性薬剤の体内動態制御Principal Investigator
- Principal Investigator
  
  向高弘
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
内用放射線治療応用に向けた放射性ヨウ素化テロメラーゼ阻害剤の開発
- Principal Investigator
  
  前田稔
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyushu University
二官能性キレートによるがん質的診断用放射性ガリウム標識PETイメージング剤の開発Principal Investigator
- Principal Investigator
  
  向高弘
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyushu University
二官能性放射性薬剤を用いた内用放射線がん治療法の確立Principal Investigator
- Principal Investigator
  
  向高弘
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Molecular imaging for noninvasive evaluation of atherosclerotic plaque vulnerability
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
放射性機能分子を用いる遺伝子発現のインビボイメージング法の開発
- Principal Investigator
  
  佐治英郎
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
二官能性放射性薬剤の分子設計に基づく放射性レニウム標識骨転移腫瘍治療薬剤の開発Principal Investigator
- Principal Investigator
  
  向高弘
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyushu University
  Kyoto University
NORMAL DISTRIBUTION OF NICOTINIC ACETYLCHOLINE RECEPTORS IN NON-SMOKERS AND SMOKERS : 5IA-SPELT STUDY.
- Principal Investigator
  
  ISHIZU Koichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
EVALUATION OF THERAPEUTIC EFFECT BY POSITRON EMISSION TOMOGRAPHY USING FLUORINATED THYMIDINE DELIVATIVE
- Principal Investigator
  
  SAGA Tsuneo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
核酸合成・PG合成酵素のインビボイメージング:腫瘍・炎症の鑑別診断への挑戦
- Principal Investigator
  
  KUGA Yuji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
腫瘍骨転移の疼痛治療を目的とする新規放射性レニウム標識薬剤の開発Principal Investigator
- Principal Investigator
  
  向高弘
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
二官能性キレートによる放射性レニウム骨腫瘍治療薬剤の開発
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
Development of a radioiodinated lipophilic cation as a new SPECT radiopharmaceutical for cancer diagnosis.
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Liver-selective delivery of 5-fluorouracil utilizing the absorption on the liver surface in rats
- Principal Investigator
  
  NAKAMURA Junzo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
Development of dosage form for the application to the liver surface for targeting of drug in the liver
- Principal Investigator
  
  NAKAMURA Junzo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagasaki University
放射性代謝物の体内動態を利用した癌診断・治療用の蛋白質放射性医薬品の開発Principal Investigator
- Principal Investigator
  
  向高弘
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
  Nagasaki University

[Journal Article] Preparation and evaluation of 111In-labeled liposomes containing phosphatidylglycerol for detection of macrophages in atherosclerotic plaques2023
- Author(s)
  Munekane Masayuki、Mori Hinako、Takada Nao、Sano Kohei、Yamasaki Toshihide、Tanaka Toru、Sasaki Naoto、Rikitake Yoshiyuki、Mukai Takahiro
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 126-127 Pages: 108388-108388
- DOI
  10.1016/j.nucmedbio.2023.108388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24291
[Journal Article] A radiolabeled nanoparticle probe coated with hyaluronic acid via electrostatic interaction to diagnose CD44-positive tumors2022
- Author(s)
  Tanaka Toshie、Sano Kohei、Munemura Mamia、Hagimori Masayori、Moriyama Rioh、Yamamoto Azusa、Ozaki Kei-ichi、Munekane Masayuki、Yamasaki Toshihide、Mukai Takahiro
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 73 Pages: 103473-103473
- DOI
  10.1016/j.jddst.2022.103473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24291
[Journal Article] Biodistribution study of indium-111-labeled PEGylated niosomes as novel drug carriers for tumor-targeting2022
- Author(s)
  Munekane Masayuki、Kosugi Asami、Yamasaki Mizuho、Watanabe Yoko、Kannaka Kento、Sano Kohei、Yamasaki Toshihide、Ogawara Ken-ichi、Mukai Takahiro
- Journal Title
  
  Journal of Drug Delivery Science and Technology
  
  Volume: 75 Pages: 103648-103648
- DOI
  10.1016/j.jddst.2022.103648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24291
[Journal Article] A radioiodinated nitroxide probe with improved stability against bioreduction for in vivo detection of lipid radicals2021
- Author(s)
  Azuma R, Yamasaki T, Sano K, Munekane M, Matsuoka Y, Yamada KI, Mukai T
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 163 Pages: 297-305
- DOI
  10.1016/j.freeradbiomed.2020.12.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00493, KAKENHI-PROJECT-19H03607, KAKENHI-PROJECT-19K17283
[Journal Article] Radioiodinated Nitroxide Derivative for the Detection of Lipid Radicals2020
- Author(s)
  Yamasaki Toshihide、Azuma Risa、Sano Kohei、Munekane Masayuki、Matsuoka Yuta、Yamada Ken-ichi、Mukai Takahiro
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 11 Issue: 1 Pages: 45-48
- DOI
  10.1021/acsmedchemlett.9b00416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17283, KAKENHI-PROJECT-19H03607, KAKENHI-PROJECT-18K14884
[Journal Article] Indium-111 labeling of high-density lipoprotein-mimicking phospholipid-styrene maleic acid copolymer complexes and its biodistribution in mice2018
- Author(s)
  Tanaka Masafumi、Hosotani Akira、Mukai Takahiro
- Journal Title
  
  Journal of Labelled Compounds and Radiopharmaceuticals
  
  Volume: 61 Issue: 11 Pages: 857-863
- DOI
  10.1002/jlcr.3668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05395
[Journal Article] An Activatable Fluorescent γ-Polyglutamic Acid Complex for Sentinel Lymph Node Imaging2017
- Author(s)
  Hagimori M, Hatabe E, Sano K, Miyazaki H, Sasaki H, Saji H, Mukai T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 3 Pages: 297-302
- DOI
  10.1248/bpb.b16-00773
- NAID
  130005398476
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05395
[Journal Article] Radiolabeled γ-polyglutamic acid complex as a nano-platform for sentinel lymph node imaging2014
- Author(s)
  Kohei Sano, Yuriko Iwamiya, Tomoaki Kurosaki, Mikako Ogawa, Yasuhiro Magata, Hitoshi Sasaki, Takashi Ohshim, Minoru Maeda, Takahiro Mukai
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 194 Pages: 310-315
- DOI
  10.1016/j.jconrel.2014.08.025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390294
[Journal Article] 6-[(2-Iminopyrrolidinyl)methyl]-5-[<125>^I]iodouracil as a potential thymidine phosphorylase-targeted radiopharmaceutical : synthesis and preliminary biological evaluation2009
- Author(s)
  T.Mukai, et al
- Journal Title
  
  J.Label. Compd. Radiopharm. 52
  
  Pages: 146-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015035
[Journal Article] Design of Ga-DOTA-based bifunctional radiopharmaceuticals : Two functional moieties can be conjugated to radiogallium-DOTA without reducing the complex stability2009
- Author(s)
  Takahiro Mukai, Jun Suwada, Kohei Sano, Mayumi Okada, Fumihiko Yamamoto, and Minoru Maeda
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: Vol.17, No.13 Issue: 13 Pages: 4285-4289
- DOI
  10.1016/j.bmc.2009.05.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390347
[Journal Article] Design of Ga-DOTA-based bifunctional radiopharmaceuticals : Two functional moieties can be conjugated to radiogallium-DOTA without reducing the complex stability2009
- Author(s)
  T.Mukai, et al
- Journal Title
  
  Bioorganic & Medicinal Chemistry 17
  
  Pages: 4285-4289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390347
[Journal Article] Targeted imaging and therapy for bone metastases : Control of phar macokinetics of bone-targeted radiopharmaceuticals2009
- Author(s)
  K. Ogawa and T. Mukai
- Journal Title
  
  J Drug Delivery Sci. Technol 19(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015035
[Journal Article] 6-[(2-Iminopyrrolidinypmethyl]-5-[125I]iodouracil as a potential thymidine phosphorylase-targeted radiopharmaceutical : synthesis and preliminary biological evaluation2009
- Author(s)
  T. Mukai, et.al.
- Journal Title
  
  J Label. Compd. Radiopharm 52(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015035
[Journal Article] Usefulness of competitive inhibitors of protein binding for improving the pharmacokinetics of 186Re-MAG3-conjugated bisphosphonate (186Re-MAG3-HBP), an agent for treatment of painful bone metastases2009
- Author(s)
  K. Ogawa, T. Mukai, et.al.
- Journal Title
  
  Eur. J Nucl. Med. Md. Imaging 36
  
  Pages: 226-121
- NAID
  120001130407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015035
[Journal Article] Targeted imaging and therapy for bone metastases : Control of phar-macokinetics of bone-targeted radiopharmaceuticals2009
- Author(s)
  K.Ogawa, T.Mukai
- Journal Title
  
  J.Drug Delivery Sci. Technol. 19
  
  Pages: 171-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015035
[Journal Article] Therapeutic effects of a ^<186>Re-complex-conjugated bisphosphonate for the palliation of metastatic bone pain in an animal model2007
- Author(s)
  Kazuma Ogawa, Takahiro Mukai, et al.
- Journal Title
  
  The Journal of Nuclear Medicine 48(1)
  
  Pages: 122-127
- NAID
  120007191066
- Data Source
  KAKENHI-PROJECT-18015041
[Journal Article] Development of bifunctional rediopharmaceuticals for targeted imaging and therapy2007
- Author(s)
  Takahiro, Mukai
- Journal Title
  
  Yakugaku Zasshi 127(12)
  
  Pages: 1937-1945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015041
[Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with atherosclerotic plaque instability-analysis in hypercholesterolemic rabbits.2007
- Author(s)
  S.Ishino, T.Mukai, N.Kume, D.Asano, M.Ogawa, Y.Kuge, M.Minami, T.Kita, M.Shiomi, H.Saji.
- Journal Title
  
  Atherosclerosis (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with atherosclerotic plaque instability-analysis in hypercholesterolemic rabbits.2007
- Author(s)
  Ishino S, Mukai T, Kume N, Asano D, Ogawa M, Kuge Y, Minami M, Kita T, Shiomi M, Saji H.
- Journal Title
  
  Atherosclerosis. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] Rhemium-186-monoaminemonoamidedithiol-conjugated bisphosphonate derivatives for bone pain palliation2006
- Author(s)
  Kazuma Ogawa, Takahiro Mukai, et al.
- Journal Title
  
  Nuclear Medicine ＆ Biology 33(4)
  
  Pages: 513-520
- Data Source
  KAKENHI-PROJECT-18015041
[Journal Article] Application of [^<18>F]FDG-PET for monitoring the therapeutic effect of anti-inflammatory drugs on stabilization of vulnerable atherosclerotic plaques.2006
- Author(s)
  M.Ogawa, Y.Magata, T.Kato, K.Hatano, S.Ishino, T.Mukai, M.Shiomi, K.Ito, H.Saji.
- Journal Title
  
  J.Nucl.Med. 48(11)
  
  Pages: 1822-1827
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] Application of [^<18>F]FDG・PET for monitoring the therapeutic effect of anti inflammatory drugs on stabilization of vulnerable atherosclerotic plaques.2006
- Author(s)
  M.Ogawa, Y.Magata, T.Kato, K.Hatano, S.Ishino, T.Mukai, M.Shiomi, K.Ito, H.Saji
- Journal Title
  
  J.Nucl.Med. 48・11
  
  Pages: 1822-1827
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] A catheter-based intravascular radiation detector of vulnerable plaques.2006
- Author(s)
  R.Hosokawa, N.Kambara, M.Ohba, T.Mukai, M.Ogawa, H.Motomura, N.Kume, H.Saji, T.Kita, R.Nohara
- Journal Title
  
  J.Nucl.Med. 47(5)
  
  Pages: 863-867
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] Development of a novel technetium-99m-chelate-conjugated bisphosphonate with high affinity for bone as a bone scintigraphic agent2006
- Author(s)
  Kazuma Ogawa, Takahiro Mukai, et al.
- Journal Title
  
  The Journal of Nuclear Medicine 47(12)
  
  Pages: 2042-2047
- Data Source
  KAKENHI-PROJECT-18015041
[Journal Article] A catherer-based intravascular radiation detector for vulnerable plaques.2006
- Author(s)
  R.Hosokawa, N.Kambara, M.Ohba, T.Mukai, M.Ogawa, H.Motomura, N.Kume, H.Saji, T.Kita, R.Nohara
- Journal Title
  
  J. Nucl. Med. 47・5
  
  Pages: 863-867
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] Therapeutic effects of ^<186>Re complex conjugated bisphosphonate in a rat model of bone metastasis.2005
- Author(s)
  Kazuma Ogawa, Takahiro Mukai, et al.
- Journal Title
  
  Yakugaku Zasshi 125・Suppll
  
  Pages: 57-58
- Data Source
  KAKENHI-PROJECT-17016055
[Journal Article] Development of a rhenium-186-labeled MAG3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals.2005
- Author(s)
  Kazuma Ogawa, Takahiro Mukai, et al.
- Journal Title
  
  Bioconjugate Chemistry 16・4
  
  Pages: 751-757
- Data Source
  KAKENHI-PROJECT-17016055
[Journal Article] A catherer-based radiation detector for endovascular detection of atheromatous plaques.2004
- Author(s)
  T.Mukai, R.Nohara, M.Ogawa, S.Ishino, N.Kambara, K.Kataoka, T.Kanoi, K.Saito, T.Motomura, J.Konishi, H.Saji.
- Journal Title
  
  Eur.J.Nucl.Med., Mol Imaging 31(9)
  
  Pages: 1299-1303
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] A catherer-based radiation detector for endovascular detection of atheromatous plaques.2004
- Author(s)
  Takahiro Mukai
- Journal Title
  
  Eur.J.Nucl.Med., Mol Imaging 31・9
  
  Pages: 1299-1303
- Data Source
  KAKENHI-PROJECT-15659008
[Journal Article] 5-[^<123>I]Iodo-A-85380 : assessment of pharmacological safety, radiation dosimetry andS PECT imaging of brain nicotinic receptors in healthy human subjects.2004
- Author(s)
  Ueda M, Iida Y, Mukai T, Ishizu K, et al.
- Journal Title
  
  Annals of Nuclear Medicine 18(4)
  
  Pages: 337-344
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591268
[Journal Article] A catherer-based radiation detector for endovascular detection of atheromatous plaques2004
- Author(s)
  T.Mukai, R.Nohara, M.Ogawa, S.Ishino, N.Kambara, K.Kataoka, T.Kanoi, S.Saito, H.Motomura, J.Konishi, H.Saji.
- Journal Title
  
  Eur. J. Nucl. Med., Mol Imaging 31・9
  
  Pages: 1299-1303
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] A catheter-based radiation detector for endovascular detection of atheromatous plaques.2004
- Author(s)
  Takahiro Mukai
- Journal Title
  
  Eur.J.Nucl.Med., Mol Imaging 31・9
  
  Pages: 1299-1303
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] 5-[^<123>I]Iodo-A-85380 : assessment of pharmacological safety, radiation dosimetry and SPECT imaging of brain nicotinic receptors in healthy human subjects.2004
- Author(s)
  Ueda M, Iida Y, Mukai T, Mamede M, Ishizu K, Ogawa M, Magata Y, Konishi J, Saji H.
- Journal Title
  
  Ann Nucl Med. 18(4)
  
  Pages: 337-344
- NAID
  10017670087
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591268
[Journal Article] 18-F-FDG accumulation in atherosclerotic plaques : immunohistochemical and PET imaging study.2004
- Author(s)
  M.Ogawa, S.Ishino, T.Mukai, D.Asano, N.Teramoto, H.Watabe, N.Kudomi, M.Shiomi, Y.Magata, H.Iida, H.Saji.
- Journal Title
  
  J.Nucl.Med. 45(7)
  
  Pages: 1245-1250
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] 18-F-FDG accumulation in atherosclerotic plaques : immunohistochemical and PET imaging study.2004
- Author(s)
  M.Ogawa, S.Ishino, T.Mukai, D.Asano, N.Teramoto, H.Watabe, N.Kudomi, M.Shiomi, Y.Magata, H.Iida, H.Saji
- Journal Title
  
  J. Nucl. Med. 45・7
  
  Pages: 1245-1250
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] Quantification of human nicotinic acetylcholine receptors with 123I-5IA SPECT.2004
- Author(s)
  Mamede M, Ishizu K, Ueda M, Mukai T, Iida Y, Fukuyama H, Saga T, Saji H.
- Journal Title
  
  J Nucl Med. 45(9)
  
  Pages: 1458-1470
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591268
[Presentation] 脂質-スチレンマレイン酸共重合体ナノディスクのがん集積に対する脂質電荷の影響評価2024
- Author(s)
  深田智也、佐野紘平、宗兼将之、山﨑俊栄、田中将史、向高弘
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24291
[Presentation] 温度応答性リポソームを駆使してがんの高コントラスト診断を達成し得る核医学診断薬の開発2024
- Author(s)
  尾嵜光希、宗兼将之、三谷柚里、酒井田なつき、佐野紘平、山﨑俊栄、向高弘、三代憲司、淵上剛志、小川数馬
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K24291
[Presentation] CD44高発現がんの光温熱治療を目的とする硫酸化ヒアルロン酸被覆金ナノロッドの開発2023
- Author(s)
  佐野紘平、田中寿枝、山﨑俊栄、向高弘
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24291
[Presentation] 血中放射能のクリアランス促進に基づきがんの高コントラスト診断を達成し得る温度応答性リポソーム型核医学診断薬の開発2023
- Author(s)
  宗兼将之、三谷柚里、酒井田なつき、佐野紘平、山﨑俊栄、向高弘、三代憲司、淵上剛志、小川数馬
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K24291
[Presentation] がんの光温熱治療を指向した硫酸化ヒアルロン酸被覆金ナノロッドの開発2023
- Author(s)
  田中寿枝、佐野紘平、宗兼将之、山﨑俊栄、向高弘
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K24291
[Presentation] 温熱療法との組み合わせによりがん細胞への取り込みを促進しうる熱応答凝集性ポリマー導入リポソーム製剤の開発2023
- Author(s)
  中田百香、佐野紘平、山﨑俊栄、向高弘
- Organizer
  第73回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-23K24291
[Presentation] 関節リウマチの診断・治療を可能とするインドシアニングリーン結合酸化鉄ナノ粒子の開発2022
- Author(s)
  佐野紘平、木島洸平、片岡若菜、八巻耕也、小山豊、佐々木直人、田中亨、力武良行、宗兼将之、山﨑俊栄、向高弘
- Organizer
  第16回日本分子イメージング学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-23K24291
[Presentation] アニオン性リポソームを母体とした動脈硬化プラーク診断用放射性プローブの開発2022
- Author(s)
  宗兼将之、森日奈子、髙田奈緒、佐野紘平、山﨑俊栄、田中亨、佐々木直人、力武良行、向高弘
- Organizer
  第5回日本核医学会分科会放射性薬品科学研究会／第21回放射性医薬品・画像診断薬研究会
- Data Source
  KAKENHI-PROJECT-23K24291
[Presentation] リポソーム膜上の化学反応に基づく薬物放出制御法の開発：化学反応速度の影響評価2022
- Author(s)
  山崎瑞穂、宗兼将之、甘中健登、山﨑俊栄、佐野紘平、向高弘
- Organizer
  第72回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-23K24291
[Presentation] Effect of Relative Configuration at C2 and C4 position of TEMPO-type Nitroxide on Ascorbate Reduction.2021
- Author(s)
  Azuma Risa, Yamasaki Toshihide, Sano Kohei, Munekane Masayuki, Mukai Takahiro
- Organizer
  ISMAR APNMR NMRSJ SEST 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 脂質ラジカルを生体検出する放射性プローブの開発 ―脳虚血再灌流モデルマウスでの評価―2021
- Author(s)
  山﨑俊栄，東里沙，佐野紘平，宗兼将之，向高弘
- Organizer
  第71回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] Substituent Effect of Benzene Ring at C2 Position of TEMPO-type Nitroxide for Ascorbate Reduction and Redox Potential.2021
- Author(s)
  Yamasaki Toshihide, Matsuda Yuto, Sano Kohei, Munekane Masayuki, Mukai Takahiro
- Organizer
  ISMAR APNMR NMRSJ SEST 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 生体内脂質ラジカルを追跡するための放射性プローブの開発および一過性脳虚血モデルを用いた評価2021
- Author(s)
  東里沙，山﨑俊栄，佐野紘平，宗兼将之，向高弘
- Organizer
  第64回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] α位置換基にベンゼン環を含むTEMPO型ニトロキシドの還元反応性の評価2021
- Author(s)
  松田優斗、山﨑俊栄、佐野紘平、宗兼将之、向高弘
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] アルコキシアミンの結合開裂反応におけるニトロキシド部分構造の置換基効果の検討2021
- Author(s)
  山﨑俊栄、坂本麻緒、佐野紘平、宗兼将之、向高弘
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 脂質ラジカルを選択的に検出する放射性プローブの開発と脳虚血/再灌流モデルでの評価2021
- Author(s)
  東里沙，山﨑俊栄，佐野紘平，宗兼将之，向高弘
- Organizer
  第4回日本核医学会分科会放射性薬品科学研究会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 脳虚血再灌流障害と脂質ラジカルとの関連性解明に向けた放射性プローブの開発2021
- Author(s)
  東里沙，山﨑俊栄，佐野紘平，宗兼将之，向高弘
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 脂質ラジカルの生体内検出に向けた放射性ヨウ素標識ニトロキシドの開発2020
- Author(s)
  東里沙、山﨑俊栄、佐野紘平、宗兼将之、松岡悠太、山田健一、向高弘
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 脂質ラジカルの核医学イメージングを目的とした新規放射性プローブの開発2020
- Author(s)
  東里沙、山﨑俊栄、佐野紘平、宗兼将之、松岡悠太、山田健一、向高弘
- Organizer
  電子スピンサイエンス学会2020
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 生体内脂質ラジカルを非侵襲検出する放射性プローブの合成及び脂質過酸化誘発モデルマウスでの評価2020
- Author(s)
  東里沙、山﨑俊栄、佐野紘平、宗兼将之、松岡悠太、山田健一、向高弘
- Organizer
  第70回　日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 生体内脂質炭素ラジカルの機能解明を指向した放射性ニトロキシドプローブの開発2019
- Author(s)
  山﨑俊栄、東里沙、佐野紘平、宗兼将之、向高弘
- Organizer
  第69回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 生体内の脂質アルキルラジカルを検出する放射性ヨウ素標識ニトロキシドプローブの開発2019
- Author(s)
  山﨑俊栄、東里沙、佐野紘平、宗兼将之、松岡悠太、山田健一、向高弘
- Organizer
  第3回日本核医学会分科会放射薬品科学研究会／第19回放射性医薬品・画像診断薬研究会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] Synthesis and evaluation of radioiodinated nitroxide probe for lipid alkyl radicals.2019
- Author(s)
  Yamasaki Toshihide, Sano Kohei, Munekane Masayuki, Mukai Takahiro.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 脂質炭素ラジカルの生体内検出を目的とした放射性ヨウ素標識ニトロキシドプローブの合成と物性・集積性評価2019
- Author(s)
  東里沙、山﨑俊栄、佐野紘平、宗兼将之、向高弘
- Organizer
  第69回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 脂質アルキルラジカルを標的とする放射性ヨウ素標識ニトロキシドプローブの合成と評価2019
- Author(s)
  山﨑俊栄、東里沙、佐野紘平、宗兼将之、向高弘
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03607
[Presentation] 葉酸受容体を標的とした核医学／蛍光デュアルイメージングプローブの開発2019
- Author(s)
  原史子，佐野紘平，三浦拓，野沢治加，宗兼将之，山﨑俊栄，萩森政頼，向高弘
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K19527
[Presentation] がんセラノスティックスを目的としたコンドロイチン硫酸被覆リポソームの作製と基礎的評価2018
- Author(s)
  宗兼将之，佐野紘平，山﨑俊栄，向高弘
- Organizer
  第28回金属の関与する生体関連反応シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] 111In標識γ-ポリグルタミン酸被覆ナノ粒子の肺転移メラノーマ核医学診断用プローブとしての有効性評価2018
- Author(s)
  田中寿枝，佐野紘平，宗兼将之，山﨑俊栄，向高弘
- Organizer
  第16回次世代を担う若手のためのフィジカル・ファーマフォーラム（PPF2018）
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] Radiolabeled chondroitin sulfate A complex as a tumor-targeted nanoparticle probe for nuclear imaging2018
- Author(s)
  Sano K., Kinugasa M., Tanaka T., Miyazaki H., Mukai T.
- Organizer
  World Molecular Imaging Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] がんの光熱治療を目的としたコンドロイチン硫酸被覆金ナノロッドの開発2018
- Author(s)
  三木麻友美，佐野紘平，田中寿枝，宗兼将之，山﨑俊栄，向高弘
- Organizer
  第68回日本薬学会近畿支部大会
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] がんの核医学診断を目的としたコンドロイチン硫酸被覆自己組織化ナノ粒子の開発2017
- Author(s)
  衣笠真由、佐野紘平、向高弘
- Organizer
  第67回　薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] Development of 111In-labeled self-orgamized nanoparticle probe for diagnosis of lung-metastatic cancer2017
- Author(s)
  T. Tanaka, K. Sano, M. Kinugasa, M. Miki, H. Miyazaki, H. Sasaki, T. Mukai
- Organizer
  第27回　金属の関与する生体関連反応シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] がんの核医学及び蛍光イメージングを目指したヒアルロン酸被覆ナノプローブの開発とがん細胞への集積性の検討2016
- Author(s)
  森山理央、萩森政頼、千石梓、向高弘
- Organizer
  第11回分子イメージング学会
- Place of Presentation
  神戸
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] フコイダン被覆自己組織化ナノ粒子によるがん細胞の傷害性の検討2016
- Author(s)
  樋口真理子、萩森政頼、向高弘
- Organizer
  第66回日本薬学会近畿支部大会
- Place of Presentation
  高槻
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] 葉酸受容体を標的とした自己組織化ナノ粒子MRIプローブの合成と基礎評価2016
- Author(s)
  香本祥汰、萩森政頼、向高弘、上田真史
- Organizer
  第16回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] 核磁気共鳴画像法による卵巣癌診断能の向上を目的とした自己組織化ナノ粒子プローブの開発2016
- Author(s)
  香本祥汰、萩森政頼、向高弘、上田真史
- Organizer
  第55回日本薬学会中国四国支部学術大会
- Place of Presentation
  岡山
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-16H05395
[Presentation] 腫瘍イメージングを目指した葉酸修飾脂質ナノディスクの細胞集積性の評価2014
- Author(s)
  辻野奈緒美, 田中将史, 向高弘
- Organizer
  第64回日本薬学会近畿支部大会
- Place of Presentation
  京都薬科大学, 京都
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] センチネルリンパ節イメージングを目指した蛍光標識γ-ポリグルタミン酸複合体の開発2014
- Author(s)
  萩森政頼, 畑辺恵里, 佐野紘平, 佐々木均, 佐治英郎, 向高弘
- Organizer
  第9回日本分子イメージング学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] 腎障害の軽減を目的としたリポソーム化ヨード造影剤の開発2014
- Author(s)
  神寶圭介, 萩森政頼, 向高弘
- Organizer
  第64回日本薬学会近畿支部大会
- Place of Presentation
  京都薬科大学, 京都
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] センチネルリンパ節の蛍光イメージングを目指したγ-ポリグルタミン酸被覆ナノ粒子の作製2014
- Author(s)
  千石梓, 畑辺恵里, 萩森政頼, 佐野紘平, 佐々木均, 佐治英郎, 向高弘
- Organizer
  第14回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都勧業館, 京都
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] アミロイド結合性を有するベンゾチアゾール誘導体の合成及び蛍光特性の評価2014
- Author(s)
  平野優里, 萩森政頼, 長谷川純子, 田中将史, 向高弘
- Organizer
  日本薬学会第13４年会
- Place of Presentation
  熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-25670540
[Presentation] チオフラビンT誘導体のアミロイド線維選択性の評価2013
- Author(s)
  長谷川純子, 平野優里, 田中将史, 小野正博, 萩森政頼, 佐治英郎, 向高弘
- Organizer
  第63回日本薬学会近畿支部大会
- Place of Presentation
  同志社女子大学（京田辺キャンパス）
- Data Source
  KAKENHI-PROJECT-25670540
[Presentation] 生体イメージングを目指したγ-ポリグルタミン酸被覆蛍光ナノ粒子の作製2013
- Author(s)
  畑辺恵里, 萩森政頼, 佐野紘平, 佐々木均, 向高弘
- Organizer
  第63回日本薬学会近畿支部大会
- Place of Presentation
  同志社女子大学（京田辺キャンパス）
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] Sentinel lymph node imaging with a novel radiolabeled γ-polyglutamic acid complex2012
- Author(s)
  Sano K., Iwamiya Y., Kurosaki T., Ogawa M., Magata Y., Sasaki H., Oshima T., Maeda M., Mukai T ,
- Organizer
  The Society of Nuclear Medicine 59th Annual Meeting
- Place of Presentation
  Miami Beach (USA)
- Year and Date
  2012-06-10
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for imaging tumors2011
- Author(s)
  Kohei Sano, Ryo Masuda, Shinya Oishi, Hayato Hisada, Kenta Shimokawa, Nobutaka Fujii, Hideo Saji, Takahiro Mukai
- Organizer
  The Society of Nuclear Medicine 58th Annual Meeting
- Place of Presentation
  San Antonio
- Year and Date
  2011-06-06
- Data Source
  KAKENHI-PROJECT-21390347
[Presentation] NAD(P)H:quinone oxidoreductase 1 を標的とする新規放射性薬剤の合成(2)2010
- Author(s)
  佐々木順一, 向高弘, ら
- Organizer
  日本薬学会第130年会
- Place of Presentation
  桃太郎アリーナ(岡山市)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20659190
[Presentation] 放射性ガリウム標識二官能性キレート、Ga-DOTA-MN2のがん低酸素領域イメージング剤としての評価2010
- Author(s)
  佐野紘平, 岡田真由美, 前田稔, 向高弘
- Organizer
  第5回日本分子イメージング学会学術集会
- Place of Presentation
  滋賀県立県民交流センター(大津市)
- Year and Date
  2010-05-23
- Data Source
  KAKENHI-PROJECT-21390347
[Presentation] Evaluation of a radiogallium-labeled bifunctional chelate, Ga-DOTA-MN2, for hypoxic tumor imaging2010
- Author(s)
  Takahiro Mukai, Kohei Sano, Mayumi Okada, Minoru Maeda
- Organizer
  The 23rd Annual Congress of the European Association of Nuclear Medicine
- Place of Presentation
  Vienna
- Year and Date
  2010-10-10
- Data Source
  KAKENHI-PROJECT-21390347
[Presentation] 放射性ガリウム標識二官能性キレート、Ga-DOTA-MN2のがん低酸素領域イメージング剤としての評価2010
- Author(s)
  佐野紘平、岡田真由美、前田稔、向高弘
- Organizer
  第5回日本分子イメージング学会学術集会
- Place of Presentation
  大津
- Year and Date
  2010-05-23
- Data Source
  KAKENHI-PROJECT-21390347
[Presentation] Evaluation of a radiogallium-labeled bifunctional chelate, Ga-DOTA-MN2, for hypoxic tumor imaging2010
- Author(s)
  Takahiro Mukai, et al.
- Organizer
  The 23rd Annual Congress of the European Association of Nuclear Medicine
- Place of Presentation
  Vienna, Austria
- Year and Date
  2010-10-10
- Data Source
  KAKENHI-PROJECT-21390347
[Presentation] A radiogallium-labeled bifunctional chelate for hypoxic tumor imaging2009
- Author(s)
  T.Mukai, et al
- Organizer
  18th International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Edmonton, Canada
- Year and Date
  2009-07-14
- Data Source
  KAKENHI-PROJECT-21390347
[Presentation] がん低酸素領域の核医学イメージングを目的とした放射性ガリウム標識二官能性キレートの開発2009
- Author(s)
  岡田真由美、諏訪田純、向高弘、佐野紘平、前田稔
- Organizer
  第9回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21390347
[Presentation] NAD(P)H:quinone oxidoreductase 1 を標的とする放射性薬剤の合成と評価2009
- Author(s)
  佐々木順一, 向高弘, ら
- Organizer
  第26回日本薬学会九州支部大会
- Place of Presentation
  九州大学(福岡市)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20659190
[Presentation] A radio-gallium-labeled bifunctional chelate for hypoxic tumor imaging2009
- Author(s)
  Takahiro Mukai, Jun Suwada, Fumihiko Yamamoto, and Minoru Maeda
- Organizer
  18th International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Edmonton
- Year and Date
  2009-07-14
- Data Source
  KAKENHI-PROJECT-21390347
[Presentation] がん低酸素領域の核医学イメージングを目的とした放射性ガリウム標識二官能性レートの開発2009
- Author(s)
  岡田真由美、諏訪田純、向高弘, ら
- Organizer
  第9回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都大学(京都市)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21390347
[Presentation] Synthesis and evaluation of 6-[(2-iminopyrrolidinyl)methyl]-5-[<125>^I]iodouracil for mapping thymidine phosphorylase in tumors2009
- Author(s)
  T.Mukai, et al
- Organizer
  The Society of Nuclear Medicine 56th Annual Meeting
- Place of Presentation
  Toronto, Canada
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-20015035
[Presentation] NAD(P)H : quinone oxidoreductase 1を標的とした新規放射性薬剤の合成2009
- Author(s)
  佐々木順一, 向高弘ら
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20659190
[Presentation] チミジンホスホリラーゼ(TP)を標的とする新規腫瘍診断用放射性薬剤の開発-TP高発現腫瘍細胞への特異的集積性評価2009
- Author(s)
  田代賢哲、向高弘, ら
- Organizer
  第9回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都大学(京都市)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20015035
[Presentation] チミジンホスホリラーゼを標的とする新規腫瘍診断用放射性薬剤の開発II-腫瘍細胞を用いたin vitro評価2009
- Author(s)
  田代賢哲、向高弘ら
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20015035
[Presentation] マトリックスメタロプロテアーゼ-2を標的とするペプチド放射性薬剤の開発-β-テトラペプチド誘導体の合成と阻害活性の評価2008
- Author(s)
  向高弘, ら
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18015041
[Presentation] Development and evaluation of radiopharmaceuticals for internal nuclide therapy of metastatic bone pain2007
- Author(s)
  小川数馬、向高弘, ら
- Organizer
  第8回がん若手ワークショップ
- Place of Presentation
  アートランドホテル蓼科
- Year and Date
  2007-08-29
- Data Source
  KAKENHI-PROJECT-18015041
[Presentation] センチネルリンパ節イメージングを目指した蛍光標識γ-ポリグルタミン酸複合体の開発
- Author(s)
  萩森政頼, 畑辺恵里, 佐野紘平, 佐々木均, 佐治英郎, 向高弘
- Organizer
  第9回日本分子イメージング学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター, 豊中
- Year and Date
  2014-05-22 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] アポE由来ペプチドを基盤とする脂質ナノディスクの腫瘍細胞への集積性評価
- Author(s)
  長谷川真理子, 田中将史, 向高弘
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール, 神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24390294
[Presentation] Development of fluorescent γ-polyglutamic acid complex for sentinel lymph node imaging
- Author(s)
  Hagimori M., Hatabe E., Sano K., Sasaki H., Saji H., Mukai T.
- Organizer
  2014 World Molecular Imaging Congress
- Place of Presentation
  COEX Convention Center, Seoul
- Year and Date
  2014-09-17 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24390294

1. SAJI Hideo (40115853)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
2. KUGA Yuji (70321958)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. MAGATA Yasuhiro (20209399)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SANO Kohei (00546476)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
5. TANAKA Masafumi (40411904)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
6. HAGIMORI Masayori (40446125)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
7. KAWASHIMA Hidekazu (70359438)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. IIDA Yasuhiko (60252425)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. SASAKI Hitoshi (00170689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
10. NAKAMURA Junzo (30115901)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. NISHIDA Koyo (20237704)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 清野泰 (50305603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 小川数馬 (30347471)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
14. 前田稔 (70101178)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 山崎俊栄 (60636710)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
16. NAKASHIMA Mikiro (00260737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SAKAEDA Toshiyuki (00304098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ISHIZU Koichi (50314224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. SAGA Tsuneo (40273445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. OYA Natsuo (70281095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TADAMURA Eiji (70303831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KUME Noriaki (20252455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. NOHARA Ryuji (80180769)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. 関興一 (60094835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 玉木長良 (30171888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 川上茂 (20322307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 山田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mukai Takahiro 向 高弘

MUKAI Takahiro 向 高弘

Research Projects

Research Products

Co-Researchers

外部刺激に応答するがん標的セラノスティックナノデバイスの開発Principal Investigator

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Development of radiolabeled probes enabling to detect reactive oxygen species separately in living bodyPrincipal Investigator

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Development of a tri-functional chelate for nuclear/fluorescence dual imagingPrincipal Investigator

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Development of self-assembled nanodevices for cancer-targeted radiotheranosticsPrincipal Investigator

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Development of a radioiodine-labeled heparanase-targeted probePrincipal Investigator

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Development of radiolabeled probes for molecular imaging of AA amyloidosisPrincipal Investigator

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Development of self-assembling nanodevices for multimodal molecular imagingPrincipal Investigator

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Development of a high spec multivalent PET probe for molecular imaging of painPrincipal Investigator

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Development of radiogallium-labeled agents for PET imaging without cyclotronPrincipal Investigator

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がんの物理療法としての分子標的型内用放射線治療法の確立Principal Investigator

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放射線により発現誘導される酵素を標的とする相乗的内用放射線治療法への挑戦Principal Investigator

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内用放射線がん治療法の確立を目的とした二官能性放射性薬剤の体内動態制御Principal Investigator

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Mukai Takahiro 向高弘

MUKAI Takahiro 向高弘