Nakaseko Chiaki 中世古知昭

… Alternative Names

NAKASEKO Chiaki 中世古知昭

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Researcher Number	30323398
Other IDs
External Links
Affiliation (Current)	2025: 国際医療福祉大学, 医学部, 主任教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 国際医療福祉大学, 医学部, 主任教授 2016 – 2019: 千葉大学, 大学院医学研究院, 特任教授 2016: 千葉大学, 医学部, 准教授 2015 – 2016: 千葉大学, 大学院医学研究院, 准教授 2013 – 2015: 千葉大学, 医学(系)研究科(研究院), 准教授 … More 2013: 千葉大学, 大学院医学研究院, 准教授 2011 – 2012: 千葉大学, 医学(系)研究科(研究院), 講師 2009 – 2010: Chiba University, 大学院・医学研究院, 講師 2008: Chiba University, 医学部附属病院, 助教 2002 – 2003: 千葉大学, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related / Hematology Except Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related / Laboratory medicine
Keywords	Principal Investigator TRAP1 / VEGF / 次世代シークエンサー / POEMS症候群 / 次世代シーケンサー / 形質細胞 / POEMS syndrome / 形質細胞腫瘍 / Osteopontin / MHC class II … More / RNAシーケンス / シングルセル解析 / RRS-1 / SEREX / allogeneic stem cell transplantation / graft-versus-host disease / graft versus myeloma effect / multiple myeloma / RRS1 / SEREX法 / 同種造血幹細胞移植 / 移植片対宿主病 / graft vs myeloma効果 / 多発性骨髄腫 / 形質細胞増殖疾患 / 形質細胞増殖性疾患 / 網羅的ゲノム解析 / 骨髄微小環境 / Whole exome sequence / モノクローナル形質細胞 / RNA sequencing / Whole exome sequencing / ダサチニブ / チロシンキナーゼ阻害薬 / STAT5 / 白血病 / チロシンキナーゼ阻害剤 / TEL-Lyn / 骨髄線維症 / 慢性骨髄増殖性疾患 / 血液腫瘍学 … More Except Principal Investigator 微小残存病変 / 次世代シークエンサー / 血液内科学 / LR11 / 骨髄腫類縁疾患 / 形質細胞 / クロナリティ / クローン / アミロイドーシス / 腫瘍クローン / 形質細胞類縁疾患 / ALアミロイドーシス / エピジェネティクス / EZH2/1共阻害剤 / BRAF / UTX / EZH2/EZH1阻害剤 / 骨髄腫モデルマウス / プロテアソーム阻害剤 / EZH2/EZH1共阻害剤 / ヒストンメチル化異常 / 多発性骨髄腫 / 熱産生 / 基礎代謝 / 褐色脂肪 / 黄斑前膜 / 肺高血圧 / アルツハイマー病 / 肺高血圧症 / リンパ腫 / 検査マーカー / 病的細胞 / ＬＲ１１ / 可溶性 / POEMS症候群 / TGFβ / 骨髄線維症 / 急性骨髄性白血病 / バイオマーカー / 血清マーカー / 血管内大細胞性B細胞型リンパ腫 / びまん性大細胞性B細胞型リンパ腫 / 急性白血病 / 悪性リンパ腫 / 予後予測システム / 新規バイオマーカー / 細胞接着 / 低酸素 / ニッチ / 白血病 / 血液腫瘍学 Less

Elucidation of the molecular pathology of AL amyloidosis by gene expression analysis of bone marrow plasma cells
- Principal Investigator
  
  Sakaida Emiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Chiba University
Elucidation of the molecular mechanism of POEMS syndrome by single cell analysis of bone marrow plasma cellsPrincipal Investigator
- Principal Investigator
  
  Nakaseko Chiaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  International University of Health and Welfare
Epigenetic pathogenesis of multiple myeloma related to drug resistance
- Principal Investigator
  
  Naoya Mimura
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
Establishment of treatment strategy for POEMS syndrome based on MRD detection method with next generation sequencer
- Principal Investigator
  
  Sakaida Emiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
Identification of the pathologically-transited immature cells diagnosed by soluble LR11
- Principal Investigator
  
  BUJO Hideaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Toho University
Genetic and Transcriptional Landscape of Plasma Cells in POEMS SyndromePrincipal Investigator
- Principal Investigator
  
  Nakaseko Chiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
Analysis of the mechanism of myelofibrosis with Smad3 knock out mice
- Principal Investigator
  
  TAKEUCHI Masahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
An establishment of serum soluble LR11, as a novel biomarker in patients with acute leukemia and malignant lymphoma
- Principal Investigator
  
  OHWADA Chikako
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
Analysis of the function of LR11 on normal leukocytes and leukemia cells
- Principal Investigator
  
  TAKEUCHI Masahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
Mechanism of myelofibrosis by a novel TEL-Lyn fusion gene.Principal Investigator
- Principal Investigator
  
  NAKASEKO Chiaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Chiba University
Identification of novel molecules associated for graft-versus-myeloma effect by SEREX screeningPrincipal Investigator
- Principal Investigator
  
  NAKASEKO Chiaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  CHIBA UNIVERSITY

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 Other

All Journal Article Presentation

[Journal Article] Genetic subtype classification using a simplified algorithm and mutational characteristics of diffuse large B‐cell lymphoma in a Japanese cohort2021
- Author(s)
  Mishina T、Oshima‐Hasegawa N、Tsukamoto S、Fukuyo M、Kageyama H、Muto T、Mimura N、Rahmutulla B、Nagai Y、Kayamori K、Hino Y、Mitsukawa S、Takeda Y、Ohwada C、Takeuchi M、Tsujimura H、Iseki T、Nakaseko C、Ikeda J、Itami M、Yokote K、Ohara O、Kaneda A、Sakaida E
- Journal Title
  
  British Journal of Haematology
  
  Volume: 195 Issue: 5 Pages: 731-742
- DOI
  10.1111/bjh.17765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-21K06881
[Journal Article] Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone therapy increases carotid intima-media thickness and plaque score with von Willebrand factor activity elevation in patients with malignant lymphoma2021
- Author(s)
  Shimizu N、Ngayama D、Watanabe Y、Yamaguchi T、Nakamura S、Ohira M、Saiki A、Onda H、Yamaoka S、Abe K、Nakaseko C、Tatsuno I
- Journal Title
  
  Journal of Chemotherapy
  
  Volume: Epub Issue: 4 Pages: 1-6
- DOI
  10.1080/1120009x.2021.1988202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] POEMS症候群に特徴的な免疫グロブリン軽鎖変異パターン2021
- Author(s)
  一色佑介，三村尚也，塚本祥吉，堺田惠美子，中世古知昭
- Journal Title
  
  血液内科
  
  Volume: in press
- NAID
  40022600467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] The combination of the tubulin binding small molecule PTC596 and proteasome inhibitors suppresses the growth of myeloma cells.2021
- Author(s)
  Nagai Y, Mimura N, Nakaseko C et al
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 2074-2074
- DOI
  10.1038/s41598-021-81577-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08338, KAKENHI-PROJECT-19K08807, KAKENHI-PROJECT-20K08276, KAKENHI-PROJECT-21K19497
[Journal Article] Successful second autologous stem-cell transplantation for patients with relapsed and refractory POEMS syndrome.2021
- Author(s)
  Shibamiya A, Ohwada C, Ishii A, Nakaseko C, et al.
- Journal Title
  
  Bone Marrow Transplant
  
  Volume: 56 Issue: 2 Pages: 517-520
- DOI
  10.1038/s41409-020-01024-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] Identification of clonal immunoglobulin λ light-chain gene rearrangements in AL amyloidosis using next-generation sequencing2021
- Author(s)
  Kimura K、Tsukamoto S、Miyazaki K、Kawajiri-Manako C、Ishii A、Rahmutulla B、Fukuyo M、Oshima-Hasegawa N、Mitsukawa S、Takeda Y、Mimura N、Takeuchi M、Ohwada C、Iseki T、Matsusaka K、Sanada M、Yokote K、Kaneda A、Ishida T、Suzuki K、Nakaseko C、Sakaida E
- Journal Title
  
  Experimental Hematology
  
  Volume: 101-102 Pages: 34-41
- DOI
  10.1016/j.exphem.2021.08.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08338, KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K08831, KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-20K08723
[Journal Article] Elevated TAT in COVID-19 Patients with Normal D-Dimer as a Predictor of Severe Respiratory Failure: A Retrospective Analysis of 797 Patients2021
- Author(s)
  Takeshita Y、Terada J、Hirasawa Y、Kinoshita T、Tajima H、Koshikawa K、Kinouchi T、Isaka Y、Shionoya Y、Fujikawa A、Tada Y、Nakaseko C、Tsushima K
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 1 Pages: 134-134
- DOI
  10.3390/jcm11010134
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] Pharmacokinetically guided, once-daily intravenous busulfan in combination with fludarabine for elderly AML/MDS patients as a conditioning regimen for allogeneic stem cell transplantation2021
- Author(s)
  Ohwada C、Yamazaki S、Shono K、Kayamori K、Hino Y、Oshima-Hasegawa N、Muto T、Tsukamoto S、Mitsukawa S、Takeda Y、Mimura N、Takeuchi M、Iseki T、Onoda M、Yokota A、Suzuki T、Ishii I、Nakaseko C、Sakaida E
- Journal Title
  
  International Journal of Hematology
  
  Volume: 114 Issue: 6 Pages: 664-673
- DOI
  10.1007/s12185-021-03188-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] Successful allogeneic bone marrow transplantation after massive gastrointestinal bleeding in a patient with myelodysplastic syndrome associated with intestinal Beh?et-like disease2021
- Author(s)
  Ishii A、Tsukamoto S、Mishina T、Izumi S、Nagai Y、Yamazaki M、Hino Y、Kayamori K、Oshima-Hasegawa N、Muto T、Mitsukawa S、Takeda Y、Mimura N、Ohwada C、Nakaseko C、Ikeda J、Sakaida E
- Journal Title
  
  Leukemia Research Reports
  
  Volume: 16 Pages: 100278-100278
- DOI
  10.1016/j.lrr.2021.100278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338, KAKENHI-PROJECT-21K06881
[Journal Article] High presepsin concentrations in bile and its marked elevation in biliary tract diseases: A retrospective analysis2021
- Author(s)
  Yamaguchi T、Ohira M、Kawagoe N、Nakamura S、Tanaka S、Oka R、Watanabe Y、Sato Y、Nagayama D、Saiki A、Matsuzawa Y、Bujo H、Terai K、Hiruta N、Tatsuno I、Nakaseko C、Kikuchi H、Matsuoka K、Yokota H、Shimizu N
- Journal Title
  
  Clinica Chimica Acta
  
  Volume: 521 Pages: 278-284
- DOI
  10.1016/j.cca.2021.07.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] Genetic and transcriptional landscape of plasma cells in POEMS syndrome2019
- Author(s)
  Nagao Y, Mimura N, Takeda J, Yoshida K, Shiozawa Y, Oshima M, Aoyama K, Nishijima D, Isshiki Y, Kayamori K, Kawajiri-Manako C, Oshima-Hasegawa N, Tsukamoto S, Mitsukawa S, Takeda Y, Ohwada C, Takeuchi M, Iseki T, Misawa S, Miyano S, Ohara O, Yokote K, Sakaida E, Kuwabara S, Sanada M, Iwama A, Ogawa S, Nakaseko C.
- Journal Title
  
  Leukemia
  
  Volume: － Issue: 7 Pages: 1723-1735
- DOI
  10.1038/s41375-018-0348-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10136, KAKENHI-PROJECT-18K08338, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-19H05656
[Journal Article] POEMS症候群の形質細胞における遺伝子異常2019
- Author(s)
  三村尚也、堺田惠美子、中世古知昭
- Journal Title
  
  腫瘍内科
  
  Volume: 24 Pages: 691-696
- NAID
  40022108670
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] POEMS syndrome: advances in molecular pathophysiology and treatment2019
- Author(s)
  Nakaseko C
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 60 Issue: 8 Pages: 979-987
- DOI
  10.11406/rinketsu.60.979
- NAID
  130007702166
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] 特集「全身性疾患と腎update」　第5章　血液疾患 4. POEMS諸侯群（Crow-Fukase症候群）・血液専門医の立場より2019
- Author(s)
  中世古知昭
- Journal Title
  
  腎と透析
  
  Volume: 86 Pages: 299-301
- Data Source
  KAKENHI-PROJECT-18K08338
[Journal Article] Dual inhibition of EZH2 and EZH1 sensitizes PRC2-dependent tumors to proteasome inhibition.2017
- Author(s)
  Ola Rizq, Naoya Mimura, Motohiko Oshima, Atsunori Saraya, Shuhei Koide, Yuko Kato, Kazumasa Aoyama, Yaeko Nakajima-Takagi, Changshan Wang, Tetsuhiro Chiba, Anqi Ma, Jian Jin, Tohru Iseki, Chiaki Nakaseko, and Atsushi Iwama
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 23(16) Issue: 16 Pages: 4817-4830
- DOI
  10.1158/1078-0432.ccr-16-2735
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09839, KAKENHI-INTERNATIONAL-15K21751, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K20959
[Journal Article] Safety and efficacy of granulocyte-colony stimulating factor monotherapy for peripheral blood stem cell collection in POEMS Syndrome.2017
- Author(s)
  Muto T, Ohwada C, Takaishi K, Isshiki Y, Nagao Y, Hasegawa N, Kawajiri-Manako C, Togasaki E, Shimizu R, Tsukamoto S, Sakai S, Takeda Y, Mimura N, Takeuchi M, Sakaida E, Misawa S, Shimizu N, Iseki T, Kuwabara S, Nakaseko C.
- Journal Title
  
  Biol Blood Marrow Transplant
  
  Volume: 23 Issue: 2 Pages: 361-363
- DOI
  10.1016/j.bbmt.2016.10.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461397, KAKENHI-PROJECT-16K09692
[Journal Article] Prognostic impact of serum soluble LR11 in newly diagnosed diffuse large B-cell lymphoma: A multicenter prospective analysis.2016
- Author(s)
  Sugita Y, Ohwada C, Kawaguchi T, Muto T, Tsukamoto S, Takeda Y1, Mimura N, Takeuchi M , Sakaida E, Shimizu N, Tanaka H, Abe D, Fukazawa M, Sugawara T, Aotsuka N, Nishiwaki K, Shono K, Ebinuma H, Fujimura K, Bujo H, Yokote K, Nakaseko C.
- Journal Title
  
  Clin Chim Acta.
  
  Volume: 463 Pages: 47-52
- DOI
  10.1016/j.cca.2016.10.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15198
[Journal Article] Acutely deteriorated extravascular volume overload during peripheral blood stem cell mobilization in POEMS syndrome: A case series with cytokine analysis.2016
- Author(s)
  Muto T, Ohwada C, Sawai S, Beppu M, Tsukamoto S, Takeda Y, Mimura N, Takeuchi M, Sakaida E, Sogawa K, Misawa S, Shimizu N, Iseki T, Nomura F, Kuwabara S, Nakaseko C.
- Journal Title
  
  Transfus Apher Sci
  
  Volume: 54 Issue: 2 Pages: 276-281
- DOI
  10.1016/j.transci.2015.10.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461397
[Journal Article] Serum soluble LR11, a novel tumor derived biomarker associated with the outcome of patients with diffuse large B-cell lymphoma.2015
- Author(s)
  Ohwada C, Yamazaki A, Kawaguchi T, Sugita Y, Takeuchi M, Shimizu N, Sakaida E, Takeda Y, Tsukamoto S, Muto T, Jiang M, Higashi M, Yokote K, Tamaru JI, Bujo H, Nakaseko C.
- Journal Title
  
  Leuk Lymphoma.
  
  Volume: 印刷中 Issue: 10 Pages: 1-4
- DOI
  10.3109/10428194.2015.1016930
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-25461409, KAKENHI-PROJECT-15K15198, KAKENHI-PROJECT-15K08366, KAKENHI-PROJECT-26670362, KAKENHI-PROJECT-26293165
[Journal Article] Potential utility of serum soluble LR11 as a diagnostic biomarker for intravascular large B-cell lymphoma2014
- Author(s)
  Kawaguchi T, Ohwada C, Takeuchi M, Shimizu N, Sakaida E, Takeda Y, Sakai S, Tsukamoto S, Yamazaki A, Sugita Y, Higashi M, Fujikawa K, Matsue K, Yokote K, Tamaru JI, Bujo H, Nakaseko C
- Journal Title
  
  Leuk Lymphoma
  
  Volume: (印刷中) Issue: 10 Pages: 2391-2394
- DOI
  10.3109/10428194.2014.880430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590413, KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-25461409
[Journal Article] The soluble form of LR11 is a regulator of hypoxia-induced, uPAR-mediated adhesion of immature hematological cells2013
- Author(s)
  Keigo Nishii, Chiaki Nakaseko, Meizi Jiang, Naomi Shimizu, Masahiro Takeuchi, Wolfgang Johann Schneider, and Hideaki Bujo
- Journal Title
  
  J Biol Chem
  
  Volume: 288(17) Pages: 11877-86
- Data Source
  KAKENHI-PROJECT-23591368
[Journal Article] The soluble form of LR11 is a regulator of hypoxia-induced, uPAR-mediated adhesion of immature hematological cells2013
- Author(s)
  Keigo Nishii, Chiaki Nakaseko, Meizi Jiang, Naomi Shimizu, Masahiro Takeuchi, Wolfgang Johann Schneider, and Hideaki Bujo
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288(17) Issue: 17 Pages: 11877-11886
- DOI
  10.1074/jbc.m112.442491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591368, KAKENHI-PROJECT-24390231, KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-24790907
[Journal Article] LR11 : a novel biomarker identified in follicular lymphoma2013
- Author(s)
  Kawaguchi T, Ohwada C, Takeuchi M, Shimizu N, Sakaida E, Takeda Y, Sakai S, Tsukamoto S, Yamazaki A, Sugita Y, Jiang M, Higashi M, Yokote K, Tamura J, Bujo H, Nakaseko C
- Journal Title
  
  Br J Haematol
  
  Volume: 163(2) Issue: 2 Pages: 277-280
- DOI
  10.1111/bjh.12467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390185, KAKENHI-PROJECT-23590413, KAKENHI-PROJECT-24390231, KAKENHI-PROJECT-24591380, KAKENHI-PROJECT-24659346, KAKENHI-PROJECT-24790907, KAKENHI-PROJECT-25461409
[Journal Article] Takeda Y, Nakaseko C, Tanaka H, Takeuchi M, Yui M, Saraya A, Miyagi S, Ohwada C, Sakaida E, Yamaguchi N, Yokote K, Hennighausen L, Iwama A.2011
- Author(s)
  Takeda Y, Nakaseko C, Tanaka H, Takeuchi M, Yui M, Saraya A, Miyagi S, Ohwada C, Sakaida E, Yamaguchi N, Yokote K, Hennighausen L, Iwama A.
- Journal Title
  
  Brit J Haematol [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591110
[Journal Article] Identification of a novel TEL-Lyn fusion gene in primary myelofibrosis.2010
- Author(s)
  Tanaka H, Takeuchi M, Takeda Y, Sakai S, Abe D, Ohwada C, Sakaida E, Shimizu N, Saito Y, Miyagi S, Iwama A, Nakaseko C.
- Journal Title
  
  Leukemia 24(1)
  
  Pages: 197-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591110
[Journal Article] Clonal expansion of non-leukemic cells expressing two novel MLL-ELL variants with distinct transforming activity.2008
- Author(s)
  Takeuchi M, Nakaseko C, Miyagi S, Takeda Y, Ozawa S, Ohwada C, Cho R, Nishimura M, Saito Y, Iwama A.
- Journal Title
  
  Leukemia 22(4)
  
  Pages: 861-864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591110
[Presentation] POEMS症候群の分子病態の解明と治療の進歩2022
- Author(s)
  Nakaseko C
- Organizer
  第47回日本骨髄腫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] マルチパラメータフローサトメトリーによるＰＯＥＭＳ症候群のクローン性形質細胞の検出2022
- Author(s)
  石井改，塚本祥吉, 三村尚也, 長井友莉恵，一色祐介，松井愼一郎，中尾三四郎，柴宮明日香，日野祐太郎, 栢森健介, 大島渚, 武藤朋也, 三川紫緒, 竹田勇輔, 水地智基，三澤園子，大和田千桂子，横手幸太郎，桑原聡，中世古知昭, 高松博幸，堺田惠美子
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] POEMS症候群のクローナル形質細胞に特有な遺伝子発現と表面マーカーの同定2021
- Author(s)
  一色佑介, 大島基彦, 三村尚也, 栢森健介, 長井友莉恵, 関真秀, 中島やえ子, 武藤朋也, 塚本祥吉, 竹田勇輔, 大和田千桂子, 三澤園子, 池田純一郎, 真田昌, 桑原聡, 鈴木穣, 堺田惠美子, 中世古知昭, 岩間厚志
- Organizer
  第83回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] 移植適応多発性骨髄腫における初回採取レジメンによる自家末梢血幹細胞採取不良例の解析2021
- Author(s)
  三村尚也, 長井友莉恵, 塚田信弘,青墳信之, 李政樹, 勝岡優奈, 若山聡雄, 鈴木利貴央, 尾崎修治, 村上博和, 中世古知昭, 堺田惠美子.
- Organizer
  日本輸血・細胞治療学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] 骨髄形質細胞シングルセル解析によるPOEMS症候群の分子病態の解明2021
- Author(s)
  中世古知昭, 織谷健司, 森直樹, 大和田千桂子, 渡部玲子, 東ヶ崎絵美, 桐戸敬介, 塚本祥吉, 三村尚也, 堺田恵美子
- Organizer
  国際医療福祉大学学会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Utxの喪失はBrafV600E変異と協調して多発性骨髄腫様疾患を誘発する2021
- Author(s)
  Ola Rizq, 三村尚也, 小出周平, モハメドリズク, 大島基彦, 百瀬修二, 中島やえ子, 青山和正, 更屋敦則, 井関徹, 堺田惠美子, 中世古知昭, 奥野豊, 田丸淳一, 本田浩章, 岩間厚志
- Organizer
  第83回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Detection of Clonal Plasma Cells in POEMS Syndrome Using Multiparameter Flow Cytometry2021
- Author(s)
  Ishii A, Tsukamoto S, Mimura N, Nagai Y, Matsui S, Nakao S, Shibamiya A, Hino Y, Kayamori K, Oshima-Hasegawa N, Muto T, Mitsukawa S, Takeda Y, Suichi , Misawa S, Ohwada C, Yokote K, Kuwabara S, Nakaseko C, Takamatsu H, Sakaida E
- Organizer
  63rd ASH Annual Meeting and Exposition
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Single plasma cell transcriptome analysis in POEMS syndrome.2020
- Author(s)
  Yusuke Isshiki, Naoya Mimura, Motohiko Oshima, Kensuke Kayamori, Masahide Seki, Kiyomi Imamura, Terumi Horiuchi, Yurie Nagai, Shokichi Tsukamoto, Yusuke Takeda, Chikako Ohwada, Sonoko Misawa, Satoshi Kuwabara, Yutaka Suzuki, Emiko Sakaida, Chiaki Nakaseko, Atsushi Iwama.
- Organizer
  25th Congress of European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] 自家移植後再燃 POEMS 症候群に対し複数回移植は有用である2020
- Author(s)
  松井慎一郎、大和田千桂子、相関祥穂、塩入勇翔、礒貝俊太郎、中尾三四郎、柴宮明日香、石井改、山﨑美貴、三科達三、長井友莉恵、日野裕太郎、木村賢司、栢森健介、大島渚、塚本祥吉、三川紫緒、竹田勇輔、三村尚也、武内正博、井関徹、中世古知昭、堺田惠美子
- Organizer
  第42回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Single plasma cell transcriptome analysis in POEMS syndrome.2020
- Author(s)
  Isshiki Y, Mimura N, Nakaseko C et al.
- Organizer
  The European Hematology Association Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Single-cell analyses unravel unique features of plasma cell clones in POEMS syndrome.2020
- Author(s)
  Isshiki Y, Mimura N, Nakaseko C et al.
- Organizer
  The 62nd Annual Meeting of the American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] 再発POEMS症候群に対する再移植の有用性2019
- Author(s)
  柴宮明日香、大和田千桂子、松井愼一郎、中尾三四郎、石井改、長井友莉恵、三科達三、山崎美貴、一色佑介、高石浩司、木村賢司、大島渚、塚本祥吉、竹田勇輔、三川紫緒、三村尚也、武内正博、井関徹、三澤園子、桑原聡、中世古知昭、堺田惠美子
- Organizer
  第81回日本血液学会総会
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Utx Insufficiency Cooperates with Braf V600E in the Induction of Myeloma in Mice2018
- Author(s)
  Ola Rizq, Naoya Mimura, Motohiko Oshima, Shuji Momose, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Atsunori Saraya, Tohru Iseki, Emiko Sakaida, Chiaki Nakaseko, Yutaka Okuno, Hiroaki Honda, Jun-ichi Tamaru, and Atsushi Iwama
- Organizer
  The 60th ASH annual meeting (SanDiego, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09839
[Presentation] 新規骨髄腫マウスモデルの作成2018
- Author(s)
  リズクオラ, 三村尚也, 井関徹, 堺田惠美子, 中世古知昭, 岩間厚志
- Organizer
  第43回日本骨髄腫学会学術集会 (千葉市)
- Data Source
  KAKENHI-PROJECT-16K09839
[Presentation] POEMS症候群の克服にむけて～分子病態解明と新規治療法の確立2018
- Author(s)
  中世古知昭
- Organizer
  第43回日本骨髄腫学会学術集会会長講演
- Invited
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] 形質細胞腫瘍の診断と治療の進歩2018
- Author(s)
  中世古知昭
- Organizer
  第19回日本検査血液学会学術集会教育講演
- Invited
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] POEMS症候群の克服に向けて　分子病態解明と新規治療法の確立2018
- Author(s)
  中世古知昭
- Organizer
  第43回日本骨髄腫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09494
[Presentation] Loss of Utx with Braf V600E induces mature B-cell tumorigenesis in a conditional mouse model2018
- Author(s)
  Ola Rizq, Naoya Mimura, Motohiko Oshima, Shuji Momose, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Atsunori Saraya, Tohru Iseki, Emiko Sakaida, Chiaki Nakaseko, Yutaka Okuno, Hiroaki Honda, Jun-ichi Tamaru, and Atsushi Iwama
- Organizer
  第80回日本血液学会総会（大阪市）
- Data Source
  KAKENHI-PROJECT-16K09839
[Presentation] Molecular analysis of pathophysiology and recent advances in the treatment of POEMS syndrome2018
- Author(s)
  中世古知昭
- Organizer
  第80回日本血液学会総会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K08338
[Presentation] Loss of Utx Cooperates with Braf V600E Mutation to Induce Post-Germinal Center B-cell Disorders in Mice2018
- Author(s)
  Ola Rizq, Naoya Mimura, Motohiko Oshima, Syuji Momose, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Atsunori Saraya, Tohru Iseki, Emiko Sakaida, Chiaki Nakaseko, Yutaka Okuno, Hiroaki Honda, Jun-ichi Tamaru, and Atsushi Iwama
- Organizer
  The 9th JSH international symposium (Kyoto, Japan)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09839
[Presentation] POEMS症候群における形質細胞の網羅的遺伝子解析2017
- Author(s)
  永尾侑平，三村尚也，竹田淳恵，大島基彦，吉田健一，堺田惠美子, 横手幸太郎, 桑原聡，眞田昌，岩間厚志，小川誠司，中世古知昭.
- Organizer
  第54回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2017-04-14
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] POEMS症候群におけるNGSを用いたλ鎖レパトア解析によるクローナルλ鎖再構成と疾患活動性の解析2017
- Author(s)
  中世古知昭，真子千華，三村尚也，福世宏枝，福世真樹，永尾侑平，大島渚，塚本祥吉，高石浩司，酒井紫緒，竹田勇輔，大和田千桂子，武内正博，井関徹，三澤園子，桑原聡，金田篤志，堺田惠美子
- Organizer
  第42回日本骨髄腫学会学術集会
- Place of Presentation
  日本赤十字看護大学(東京都)
- Year and Date
  2017-05-27
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] Molecular mechanism behind the synergistic activity of proteasome inhibition and PRC2 inhibition in the treatment of multiple myeloma.2016
- Author(s)
  14.Ola Rizq, Naoya Mimura, Motohiko Oshima, Atsunori Saraya, Shuhei Koide, Yuko Kato, Kazumasa Aoyama, Yaeko Nakajima-Takagi, Changshan Wang, Anqi Ma, Jian Jin, Tohru Iseki, Chiaki Nakaseko, and Atsushi Iwama.
- Organizer
  The 58th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Diego Convention Center, California, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09839
[Presentation] Clonal IGL gene rearrangements detected by NGS is correlated with disease status in POEMS syndrome2016
- Author(s)
  川尻千華, 三村尚也, 南波宏枝, 福世真樹, 永尾侑平, 東ヶ崎絵美, 清水亮, 竹田勇輔, 酒井紫緒, 大和田千桂子, 武内正博, 堺田惠美子, 井関徹, 三澤園子, 桑原聡, 築地信, 金田篤志, 中世古知昭.
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] Clonal immunoglobulin λ light-chain gene rearrangements detected by next generation sequencing in POEMS Syndrome.2016
- Author(s)
  Chika Kawajiri-Manako, Naoya Mimura, Masaki Fukuyo, Hiroe Namba-Fukuyo, Bahityar Rahmutulla, Yuhei Nagai, Yusuke Takeda, Chikako Ohwada, Masahiro Takeuchi, Emiko Sakaida, Sonoko Misawa, Koutaro Yokote, Satoshi Kuwabara, Atsushi Kaneda, Chiaki Nakaseko
- Organizer
  The 58th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09494
[Presentation] Clonal immunoglobulin λ light-chain gene rearrangements detected by next generation sequencing in POEMS Syndrome.2016
- Author(s)
  Kawajiri-Manako C, Mimura N, Fukuyo M, Namba-Fukuyo H, Rahmutulla B, Nagao Y, Togasaki E, Shimizu R, Hasegawa N, Sakai S, Takeda Y, Ohwada C, Takeuchi M, Sakaida E, Iseki T, Misawa S, Yokote K, Tsuiji M, Kuwabara S, Kaneda A, Nakaseko C.
- Organizer
  The 58th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] Clonal IGL gene rearrangements detected by NGS is correlated with disease status in POEMS syndrome2016
- Author(s)
  川尻千華, 三村尚也, 南波宏枝, 福世真樹, 永尾侑平, 東ヶ崎絵美, 清水亮, 竹田勇輔, 酒井紫緒, 大和田千桂子, 武内正博, 堺田惠美子, 井関徹, 三澤園子, 桑原聡, 築地信, 金田篤志, 中世古知昭.
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K09494
[Presentation] Clonal IGL gene rearrangements detected by NGS is correlated with disease status in POEMS syndrome2016
- Author(s)
  Chika Kawajiri, Naoya Mimura, Yuhei Nagao, Emi Togasaki, Ryo Shimizu, Nagisa Hasegawa, Yusuke Takeda, Shio Sakai, Chikako Ohwada, Masahiro Takeuchi, Emiko Sakaida, Tohru Iseki, Sonoko Misawa, Satoshi Kuwabara, Atsushi Kaneda, Chiaki Nakaseko
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] Distinctive genetic features of plasma cells in POEMS syndrome.2016
- Author(s)
  Nagao Y, Mimura N, Takeda J, Oshima M, Yoshida K, Shiozawa Y, Aoyama K, Saraya A, Koide S, Shiraishi Y, Chiba C, Tanaka H, Kawajiri-Manako C, Hasegawa N, Sakai S, Takeda Y, Ohwada C, Takeuchi M, Sakaida E, Iseki T, Misawa S, Yokote K, Miyano S, Ohara O, Kuwabara S, Sanada M, Iwama A, Ogawa S, Nakaseko C.
- Organizer
  The 58th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] EZH2・EZH1阻害剤は骨髄腫細胞のボルテゾミブ感受性を増強する2016
- Author(s)
  Ola Rizq, 三村尚也, 井関徹, 中世古知昭, 岩間厚志
- Organizer
  第41回日本骨髄腫学会学術集会
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-16K09839
[Presentation] Combined inhibition of PRC2 and proteasome as a potential therapy for multiple myeloma2016
- Author(s)
  Ola Rizq, 三村尚也, 大島基彦, 更屋敦則, 小出周平, 加藤裕子, 青山和正, 井関徹, 中世古知昭, 岩間厚志
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09839
[Presentation] PRC2 Inhibition Sensitizes Myeloma Cells to Proteasome Inhibitor.2016
- Author(s)
  Ola Rizq, Naoya Mimura, Motohiko Oshima, Atsunori Saraya, Shuhei Koide, Yuko Kato, Kazumasa Aoyama, Changshan Wang, Tetsuhiro Chiba, Tohru Iseki, Chiaki Nakaseko, and Atsushi Iwama.
- Organizer
  The 5th Japanese Cancer Association (JCA) - American Association for Cancer Research (AACR) Special Joint Conference
- Place of Presentation
  Tokyo Bay Maihama Hotel Club Resort（千葉県浦安市）
- Year and Date
  2016-07-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09839
[Presentation] 血清可溶型LR11（sLR11）のIntravascular large B-cell lymphoma（IVLBCL）に対する診断有用性2014
- Author(s)
  大和田千桂子、中世古知昭、川口岳晴、竹田勇輔、武内正博、堺田惠美子、清水直美、横手幸太郎
- Organizer
  第111回日本内科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461409
[Presentation] 濾胞性リンパ腫における可溶型LR11のバイオマーカーとしての有用性2013
- Author(s)
  川口岳晴，大和田千桂子、山崎敦子、塚本祥吉、酒井紫緒、竹田勇輔、武内正博、堺田恵美子、清水直美、横手幸太郎、武城英明、中世古知昭.
- Organizer
  第50回日本臨床分子医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461409
[Presentation] LR11 plays critical roles in leukemogenesis of AML by regulating cell adhesion and homing ability2013
- Author(s)
  西居圭吾、中世古知昭、武内正博、清水直美、大和田千佳子、塚本祥吉、川口岳晴、姜美子、岩間厚志、武城英明
- Organizer
  第75回日本血液学会総会
- Year and Date
  2013-10-11
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] LR11 Plays a Critical Role in Leukemogenesis of Acute Myeloid Leukemia by Regulating Adhesion and Homing Ability to Bone Marrow2012
- Author(s)
  西居圭吾、武内正博、中世古知昭、武城英明ほか
- Organizer
  54th ASH annual meeting and exposition(米国血液学会年次総会)
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] LR11 regulates the hypoxia-induced hematopoietic immature cell adhesion2012
- Author(s)
  西居圭吾、武内正博、中世古知昭、武城英明ほか
- Organizer
  第74回日本血液学会総会
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] LR11 regulates the hypoxia-induced hematopoietic immature cell adhesion.2012
- Author(s)
  西居圭吾、武内正博、中世古知昭、武城英明　ほか
- Organizer
  日本血液学会総会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] Serum soluble LR11 is a promising novel biomarker for B cell lymphoma2012
- Author(s)
  川口岳晴、大和田千桂子、酒井紫緒、竹田勇輔、清水直美、武内正博、堺田恵美子、田久保耕平、海老沼宏幸、深町勇、東守洋、田丸淳一、横手幸太郎、武城英明、中世古知昭
- Organizer
  53rd ASH annual meeting and exposition(米国血液学会年次総会)
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] 可溶型LR11はCD87・CD11b複合体を介して単球系THP-1細胞を活性化する2011
- Author(s)
  塚本祥吉、武内正博、杉田泰雅、山崎敦子、川口岳晴、酒井紫緒、竹田勇輔、大和田千桂子、清水直美、堺田恵美子、西居圭吾、姜美子、横手幸太郎、武城英明、中世古知昭
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] Serum soluble LR11 is a promising novel biomarker for B cell lymphoma.2011
- Author(s)
  川口岳晴、大和田千桂子、酒井紫緒、竹田勇輔、清水直美、武内正博、堺田恵美子、田久保耕平、海老沼宏幸、深町勇、東守洋、田丸淳一、横手幸太郎、武城英明、中世古知昭
- Organizer
  53ｒｄ　ASH annual meeting and exposition　（米国血液学会年次総会）
- Place of Presentation
  サンディエゴ
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] Soluble LR11/SorLA, a Potential Circulating Marker Indicating the G-CSF-Induced Mobilization of Hematopoietic Stem Cells, Is a Modulator of G-CSF-Mediated Migration of HL-60 Cells2011
- Author(s)
  清水直美、中世古知昭、武内正博、大和田千桂子、塚本祥吉、川口岳晴、西居桂吾、姜美子、横手幸太郎、深町勇、武城英明
- Organizer
  53rd ASH annual meeting and exposition(米国血液学会年次総会)
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] 可溶型LR11はCD87・CD11b複合体を介して単球系THP-1細胞を活性化する2011
- Author(s)
  塚本祥吉、武内正博、杉田泰雅、山崎敦子、川口岳晴、酒井紫緒、竹田勇輔、大和田千桂子、清水直美、堺田恵美子、西居圭吾、姜美子、横手幸太郎、武城英明、中世古知昭
- Organizer
  第73回日本血液学会学術集会
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] 可溶性LR11は白血病細胞株HL-60の新たな走化性因子であり、G-CSFによる遊走能を増強する2011
- Author(s)
  清水直美、中世古知昭、酒井紫緒、塚本祥吉、川口岳晴、竹田勇輔、大和田千桂子、武内正博、堺田恵美子、井関徹、西居桂吾、姜美子、横手幸太郎、武城英明
- Organizer
  第73回日本血液学会学術集会
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] Serum soluble LR11 is a promising novel biomarker for malignant lymphoma2011
- Author(s)
  川口岳晴、大和田千桂子、酒井紫緒、竹田勇輔、清水直美、武内正博、堺田恵美子、田久保耕平、海老沼宏幸、深町勇、東守洋、田丸淳一、横手幸太郎、武城英明、中世古知昭
- Organizer
  第73回日本血液学会学術集会
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] 可溶性LR11は白血病細胞株HL-60の新たな走化性因子であり、G-CSFによる遊走能を増強する2011
- Author(s)
  清水直美、中世古知昭、酒井紫緒、塚本祥吉、川口岳晴、竹田勇輔、大和田千桂子、武内正博、堺田恵美子、井関徹、西居桂吾、姜美子、横手幸太郎、武城英明
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] Serum soluble LR11 is a promising novel biomarker for malignant lymphoma.2011
- Author(s)
  川口岳晴、大和田千桂子、酒井紫緒、竹田勇輔、清水直美、武内正博、堺田恵美子、田久保耕平、海老沼宏幸、深町勇、東守洋、田丸淳一、横手幸太郎、武城英明、中世古知昭
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] Soluble LR11/SorLA, a Potential Circulating Marker Indicating the G-CSF-Induced Mobilization of Hematopoietic Stem Cells, Is a Modulator of G-CSF-Mediated Migration of HL-60 Cells2011
- Author(s)
  清水直美、中世古知昭、武内正博、大和田千桂子、塚本祥吉、川口岳晴、西居桂吾、姜美子、横手幸太郎、深町勇、武城英明
- Organizer
  53ｒｄ　ASH annual meeting and exposition　（米国血液学会年次総会）
- Place of Presentation
  サンディエゴ
- Data Source
  KAKENHI-PROJECT-23591368
[Presentation] Direct Activation of STAT5 by TEL-Lyn Fusion Protein Promotes Induction of Myeloproliferative Neoplasms with Myelofibrosis.2010
- Author(s)
  竹田勇輔, 中世古知昭, 田中宏明, 武内正博, 由井麻紀子, 更家敦則, 宮城聡, 大和田千桂子, 堺田恵美子, 横手幸太郎, 岩間厚志
- Organizer
  The 52th American Society of Hematology
- Place of Presentation
  Orlando
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20591110
[Presentation] TEL-Lyn融合タンパクはStat5を活性化し骨髄線維症を誘発する2010
- Author(s)
  竹田勇輔, 中世古知昭, 田中宏明, 武内正博, 由井麻紀子, 更家敦則, 宮城聡, 大和田千桂子, 堺田恵美子, 山口直人, 横手幸太郎, Lothar Hennighausen, 岩間厚志
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20591110
[Presentation] The Efficacy and Long-Term Outcomes of ASCT in POEMS Syndrome: A Multicenter Retrospective Study in Japan
- Author(s)
  Chika Kawajiri, Emiko Sakaida, Chikako Ohwada, Toshihiro Miyamoto, Taichi Azuma, Jun Taguchi, Takehiko Mori, Yuichi Hasegawa, Tadakazu Kondo, Toshiaki Yujiri, Makoto Yoshimitsu, Mitsuru Tsudo, Toshihiko Iwasaki, Akio Shigematsu, Ritsuro Suzuki, Yoshiko Atsuta, Makoto Hirokawa, Hisashi Sakamaki, Chiaki Nakaseko.
- Organizer
  The 56th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Francisco
- Year and Date
  2014-12-05 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26461397
[Presentation] 血管内大細胞性リンパ腫（IVLBCL）の診断におけるLR11の有用性
- Author(s)
  大和田千桂子、中世古知昭、川口岳晴、竹田勇輔、武内正博1、堺田恵美子、清水直美、横手幸太郎
- Organizer
  第111回日本内科学会総会
- Place of Presentation
  東京、国際フォーラム
- Year and Date
  2014-04-11 – 2014-04-13
- Data Source
  KAKENHI-PROJECT-25461409
[Presentation] LR11 plays a critical role in leukemogenesis of AML by regulating cell adhes ion and homing ability
- Author(s)
  西居桂吾、中世古知昭、武内正博、清水直美、大和田千桂子、塚本祥吉、川口岳晴、姜美子、岩間厚志、武城英明
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591368

1. TAKEUCHI Masahiro (50466702)

# of Collaborated Projects: 6 results

# of Collaborated Products: 27 results
2. OHWADA Chikako (80436352)

# of Collaborated Projects: 6 results

# of Collaborated Products: 29 results
3. SAKAIDA Emiko (60422218)

# of Collaborated Projects: 5 results

# of Collaborated Products: 29 results
4. IWAMA Atsushi (70244126)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
5. BUJO Hideaki (80291300)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
6. Naoya Mimura (00422220)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 塚本祥吉 (00814617)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
8. MIMURA Naoya (00710229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 35 results
9. YOKOTE Koutaro (20312944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. NISHIMURA Miki (10292690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. JIANG Meizi (00624066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHIMIZU Naomi (30375802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. HIRUTA Nobuyuki (50201736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAGAO Tateki (20167555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. IKEUCHI Takeshi (20372469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Iseki Tohru (10232365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
17. Oshima Motohiko (70506287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
18. 竹田勇輔 (60772746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
19. SANADA Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 東守洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 田丸淳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakaseko Chiaki 中世古 知昭

NAKASEKO Chiaki 中世古 知昭

Research Projects

Research Products

Co-Researchers

Elucidation of the molecular pathology of AL amyloidosis by gene expression analysis of bone marrow plasma cells

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Elucidation of the molecular mechanism of POEMS syndrome by single cell analysis of bone marrow plasma cellsPrincipal Investigator

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Epigenetic pathogenesis of multiple myeloma related to drug resistance

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Establishment of treatment strategy for POEMS syndrome based on MRD detection method with next generation sequencer

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Identification of the pathologically-transited immature cells diagnosed by soluble LR11

Principal Investigator

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Genetic and Transcriptional Landscape of Plasma Cells in POEMS SyndromePrincipal Investigator

Principal Investigator

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Analysis of the mechanism of myelofibrosis with Smad3 knock out mice

Principal Investigator

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An establishment of serum soluble LR11, as a novel biomarker in patients with acute leukemia and malignant lymphoma

Principal Investigator

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Analysis of the function of LR11 on normal leukocytes and leukemia cells

Principal Investigator

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Mechanism of myelofibrosis by a novel TEL-Lyn fusion gene.Principal Investigator

Principal Investigator

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Identification of novel molecules associated for graft-versus-myeloma effect by SEREX screeningPrincipal Investigator

Principal Investigator

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Research Institution

[Journal Article] Genetic subtype classification using a simplified algorithm and mutational characteristics of diffuse large B‐cell lymphoma in a Japanese cohort2021

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[Journal Article] Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone therapy increases carotid intima-media thickness and plaque score with von Willebrand factor activity elevation in patients with malignant lymphoma2021

Author(s)

Journal Title

DOI

Nakaseko Chiaki 中世古知昭

NAKASEKO Chiaki 中世古知昭

[Journal Article] 特集「全身性疾患と腎update」　第5章　血液疾患 4. POEMS諸侯群（Crow-Fukase症候群）・血液専門医の立場より2019