Kojima Naoshi 小島直

… Alternative Names

KOJIMA Naoshi 小島直

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Researcher Number	30356985
Other IDs
Affiliation (Current)	2023: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help	2023: 国立研究開発法人産業技術総合研究所, その他部局等, 研究員 2017 – 2022: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2015 – 2016: 国立研究開発法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 2008 – 2009: National Institute of Advanced Industrial Science and Technology, ゲノムファクトリー研究部門, 主任研究員 2007: National Institute of Advanced Industrial Science and Technology, ゲノムファクトリー研究部門, 主任研究員 2004 – 2006: National Institute of Advanced Industrial Science and Technology, Research Institute of Genome-based Biofactory, Research Scientist, ゲノムファクトリー研究部門, 研究員 2003: 独立行政法人産業技術総合研究所, 生物機能工学研究部門, 研究員
Review Section/Research Field	Principal Investigator Living organism molecular science / Chemical pharmacy / Basic Section 34020:Analytical chemistry-related Except Principal Investigator Living organism molecular science / Biomolecular chemistry / Analytical chemistry / Basic Section 28050:Nano/micro-systems-related
Keywords	Principal Investigator 核酸 / 遺伝子 / 分子認識 / 合成化学 / 検出 / 核酸誘導体 / デアザヌクレオシド / 1-デアザグアノシン / 核酸合成酵素 / ポリメラーゼ … More / オリゴヌクレオチド / 合成後修飾 / 機能生核酸 / 機能性核酸 / 塩基対 / ミスマッチ塩基対 / 損傷塩基 / 低分子リガンド / 疎水性相互作用 / 親水性相互作用 / 遺伝子検出 / 生物発光 / ルシフェリン / 核酸プローブ / 核酸化学 … More Except Principal Investigator OPN / siRNA / RNA / オステオポンチン / 転移 / concanavalin A / 肝炎 / オリゴヌクレオチド / Concanavalin A / 癌転移 / RNAi / 炎症疾患 / リン酸化糖タンパク質 / Osteopontin / metastasis / concanavarin A / hepatitis / oligonucleotide / 生物発光 / ルシフェリン / ルシフェラーゼ / 発光ゴカイ / 発光生物 / ゴカイ / エピジェネティクス / マイクロデバイス / メチル化DNA / 一分子 / 一細胞 / µTAS / バイオセンサ / メチルシトシン / 分析科学 / 微粒子 / 電気化学発光 / マーカー分子検出 / 電極 / がん Less

遺伝子検出技術の高感度化に向けた生物発光の利用Principal Investigator
- Principal Investigator
  
  小島直
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
１細胞単位電気化学発光計測技術によるマーカー分子微量発現がん細胞の超高感度検出
- Principal Investigator
  
  金賢徹
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28050:Nano/micro-systems-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Epigenome analysis on an array device for single cell / genome
- Principal Investigator
  
  KURITA RYOJI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Analytical chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Novel molecular mechanisms of luminous fireworm
- Principal Investigator
  
  Mitani Yasuo
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Building up the bioluminescence molecule on the nucleic acid sequence and its application to gene detection technologyPrincipal Investigator
- Principal Investigator
  
  KOJIMA Naoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Synthesis of novel chemical ligand that selectively bind to the unstabilized base pairs formed in DNAPrincipal Investigator
- Principal Investigator
  
  KOJIMA Naoshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
分子間相互作用を利用したRNA末端部位標識化試薬の開発Principal Investigator
- Principal Investigator
  
  小島直
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
非天然型ヌクレオシドの合成と、これを利用した核酸合成酵素認識機構の解析Principal Investigator
- Principal Investigator
  
  小島直
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Investigation of regulatory mechanism of homeostasis using functional nucleic acids.
- Principal Investigator
  
  KOMATSU Yasuo, 大塚榮子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

All 2021 2020 2019 2018 2017 2016 2009 2008 2006 2005 2003

All Journal Article Presentation Patent

[Journal Article] Development of gapmer antisense oligonucleotide with deoxyribonucleic guanidine (DNG) modifications2019
- Author(s)
  Kojima Naoshi、Shrestha Ajaya R.、Akisawa Takuya、Piao Haishun、Kizawa Hideki、Ohmiya Yoshihiro、Kurita Ryoji
- Journal Title
  
  Nucleosides, Nucleotides & Nucleic Acids
  
  Volume: 39 Pages: 258-269
- DOI
  10.1080/15257770.2019.1668563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03084
[Journal Article] Immobilization of DNA on Biosensing Devices with Nitrogen Mustard?Modified Linkers2019
- Author(s)
  栗之丸隆章、小島直、栗田僚二
- Journal Title
  
  Current Protocols in Nucleic Acid Chemistry
  
  Volume: 77
- DOI
  10.1002/cpnc.85
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06192, KAKENHI-PROJECT-17H03084, KAKENHI-PROJECT-18K14258
[Journal Article] Sequential Assessment of Multiple Epigenetic Modifications of Cytosine in Whole Genomic DNA by Surface Plasmon Resonance2019
- Author(s)
  栗之丸隆章、小島直、栗田僚二
- Journal Title
  
  Analytical Chemistry
  
  Volume: 91 Pages: 13933-13939
- DOI
  10.1021/acs.analchem.9b03423
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06192, KAKENHI-PROJECT-17H03084, KAKENHI-PROJECT-18K14258
[Journal Article] Immobilization of DNA with nitrogen mustard?biotin conjugate for global epigenetic analysis2018
- Author(s)
  小島直、須田友美、栗之丸隆章、栗田僚二
- Journal Title
  
  Analytica Chimica Acta
  
  Volume: 1043 Pages: 107-114
- DOI
  10.1016/j.aca.2018.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06192, KAKENHI-PROJECT-18K14258, KAKENHI-PROJECT-17H03084
[Journal Article] An alkylating immobilization linker for immunochemical epigenetic assessment2017
- Author(s)
  Kurinomaru Takaaki、Kojima Naoshi、Kurita Ryoji
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Pages: 8308-8311
- DOI
  10.1039/c7cc02883k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03084, KAKENHI-PROJECT-15K14933
[Journal Article] Development of a 3′-amino linker with high conjugation activity and its application to conveniently cross-link blunt ends of a duplex.2016
- Author(s)
  Keiko Kowata, Naoshi Kojima, Yasuo Komatsu
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 24 Pages: 2108-2113
- DOI
  10.1016/j.bmc.2016.03.039
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14933, KAKENHI-PROJECT-25293030
[Journal Article] Development of novel chemical probes to detect abasic sites in DNA2009
- Author(s)
  Naoshi Kojima
- Journal Title
  
  Nucleic Acids Symposium Series 53
  
  Pages: 45-46
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Efficient synthesis of oligonucleotide conjugates on solid-support using an (aminoethoxycarbonyl)aminohexyl group for 5'-terminal modification2009
- Author(s)
  Naoshi Kojima
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters 19
  
  Pages: 2144-2147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Efficient synthesis of oligonucleotide conjugates on solid-support using an (aminoethoxycarbonyl)- aminohexyl group for 5'-terminal modification2009
- Author(s)
  Kojima, N., Takebayashi, T., Mikami, A., Ohtsuka, E., Komatsu, Y.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 19
  
  Pages: 2144-2147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Construction of highly reactive probes for abasic site detection by introduction of an aromatic and a guanidine residue into an aminooxy group2009
- Author(s)
  Kojima, N., Takebayashi, T., Mikami, A., Ohtsuka, E., Komatsu, Y.
- Journal Title
  
  J. Am. Chem. Soc. 131
  
  Pages: 13208-13209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Construction of highly reactive probes for abasic site detection by introduction of an aromatic and a guanidine residue into an aminooxy group2009
- Author(s)
  Naoshi Kojima
- Journal Title
  
  Journal of the American Chemical Society 131
  
  Pages: 13208-13209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Comparison of the chemical properties of a novel amino-linker with various amino modifications2008
- Author(s)
  Kojima, N., Takebayashi, T., Mikami, A., Sugino, M., Ohtsuka, E., Komatsu, Y.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 463-464
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Comparison of the chemical properties of a novel amino-linker with various aminomodifications2008
- Author(s)
  Kojima, N.
- Journal Title
  
  Nucleic Acids Symposium Series 52
  
  Pages: 463-464
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Construction of an aminooxy derivative for RNA and DNA labeling2008
- Author(s)
  Komatsu, Y., Kojima, N., Takebayashi, T., Mikami, A., Sugino, M., Ohtsuka, E.
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 393-394
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Construction of an aminooxy derivative for RNA and DNA labeling2008
- Author(s)
  Kojima, N.
- Journal Title
  
  Nucleic Acids Symposium Series 52
  
  Pages: 393-394
- Data Source
  KAKENHI-PROJECT-20710179
[Journal Article] Enhanced reactivity of amino-modified oligonucleotides by insertion of aromatic residue2006
- Author(s)
  Kojima, N
- Journal Title
  
  Bioorganic ＆ Medicinal Chemistry Letters 16・19
  
  Pages: 5118-5121
- Data Source
  KAKENHI-PROJECT-18710199
[Journal Article] High throughput purification of amino-modified oligonucleotides and its application to novel detection system of gene expression.2005
- Author(s)
  Kojima, N
- Journal Title
  
  Nucleic Acids Symposium Series No.49
  
  Pages: 181-182
- Data Source
  KAKENHI-PROJECT-16710166
[Journal Article] Generation of an Abasic Site in an Oligonucleotide by Using Acid-Labile 1-Deaza-2'-deoxyguanosine and its Application to Postsynthetic Modification2005
- Author(s)
  Kojima, N
- Journal Title
  
  Organic Letters 7・4
  
  Pages: 709-712
- Data Source
  KAKENHI-PROJECT-16710166
[Journal Article] Generation of an abasic site in an oligonucleotide by using acid-labile 1-deaza-2'-deoxyguanosine and its application to postsynthetic modification.2005
- Author(s)
  Kojima, N
- Journal Title
  
  Organic Letters 7・4
  
  Pages: 709-712
- Data Source
  KAKENHI-PROJECT-15310157
[Journal Article] Generation of an abasic site in an oligonucleotide by using acid-labile 1-deaza-2'-deoxyguanosine and its application to postsynthetic modification.2005
- Author(s)
  Kojima, N.
- Journal Title
  
  Organic Letters 7
  
  Pages: 709-712
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310157
[Journal Article] A new, but old, nucleoside analog : the first synthesis of l-deaza-2'-deoxy-guanosine and its properties as a nucleoside and as oligodeoxynucleotides.2003
- Author(s)
  Kojima, N.
- Journal Title
  
  Nucleic Acids Research 31
  
  Pages: 7175-7188
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310157
[Patent] 微小構造体、その作製方法およびそれを利用した分子検出方法2021
- Inventor(s)
  金賢徹、加藤大、小島直、山村昌平、鎌田智之
- Industrial Property Rights Holder
  国立研究開発法人産業技術総合研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20H02597
[Patent] 核酸の液中固定化剤2017
- Inventor(s)
  栗田僚二、小島直、栗之丸隆章
- Industrial Property Rights Holder
  栗田僚二、小島直、栗之丸隆章
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-033930
- Filing Date
  2017-02-24
- Data Source
  KAKENHI-PROJECT-15K14933
[Presentation] 電気化学発光計測によるがん細胞表面発現マーカー分子検出技術の開発2021
- Author(s)
  内山皐生、栗山愛理、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  第82回応用物理学会秋季学術講演会
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] Detection of target biomolecules expressed on a cell surface based on electrochemiluminescence by using cup-shaped microelectrode2021
- Author(s)
  栗山愛理、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  Biosensors 2021, 31st Anniversary World congress on Biosensors
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] カップ形状微小電極への細胞捕捉と電気化学発光計測による細胞表面発現分子検出技術の開発2020
- Author(s)
  栗山愛理、内山皐生、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  日本応用物理学会第81回秋季学術講演会
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] Electrochemiluminescence-Based Detection of Cell Surface Biomolecules by Using Cup-Shaped Microelectrodes2020
- Author(s)
  栗山愛理、鎌田智之、加藤大、小島直、山村昌平、金賢徹
- Organizer
  PRiME2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02597
[Presentation] NITROGEN-MUSTARD COATED MAGNETIC BEADS FOR HYBRIDIZATION AND ELUTION-FREE CIRCULATING TUMOR DNA DETECTION2019
- Author(s)
  Benediktus Nixon Hapsianto,小島直、栗田僚二,Hitoshi Yamagata,Hiroyuki Fujita,Teruo Fujii,Soo Hyeon Kim
- Organizer
  MicroTAS 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03084
[Presentation] Immunochemical Assessment of 5-Methylcytosine and 5-Hydroxymethylcytosine Using Nitrogen Mustard Modified Linkers2019
- Author(s)
  小島直、須田友美、栗之丸隆章、栗田僚二
- Organizer
  The 46th International Symposium on Nucleic Acids Chemistry, The 3rd Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03084
[Presentation] Immunochemical Sensing of Epigenomic Modification Using An Alkylating Immobilization Linker2017
- Author(s)
  Takaaki Kurinomaru, Naoshi Kojima, Ryoji Kurita
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry / The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry
- Data Source
  KAKENHI-PROJECT-17H03084
[Presentation] Immunochemical Sensing of Epigenomic Modification Using An Alkylating Immobilization Linker2017
- Author(s)
  栗之丸隆章、小島直、栗田僚二
- Organizer
  第44回国際核酸化学シンポジウム（ISNAC2017、日本核酸科学会第1回年会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14933
[Presentation] エピゲノムのオンチップ分析に向けたアルキル化リンカーの創成2017
- Author(s)
  栗田僚二, 栗之丸隆章, 小島直
- Organizer
  化学とマイクロ・ナノシステム学会第36回研究会
- Data Source
  KAKENHI-PROJECT-17H03084
[Presentation] 抗がん剤を有する新規リンカー分子を用いたメチル化DNA免疫センサーの開発2017
- Author(s)
  栗之丸隆章、小島直、吉岡恭子、栗田僚二
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学日吉キャンパス（神奈川県横浜市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K14933
[Presentation] Development of novel chemical probes to detect abasic sites in DNA2009
- Author(s)
  小島直
- Organizer
  6^<th> International Symposium on Nucleic Acids Chemistry and 36^<th> Symposium on Nucleic Acids Chemistry
- Place of Presentation
  岐阜県高山市
- Year and Date
  2009-09-29
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] Development of novel chemical probes to detect abasic sites in DNA2009
- Author(s)
  小島直、小松知志恵、三上暁子、大塚榮子、小松康雄
- Organizer
  第6回国際核酸化学シンポジウム
- Place of Presentation
  岐阜県高山市
- Year and Date
  2009-09-29
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] DNA脱塩基部位に高効率で反応する試薬の開発2009
- Author(s)
  小島直、小松知志恵、三上暁子、大塚榮子、小松康雄
- Organizer
  日本環境変異原学会第38回大会
- Place of Presentation
  静岡県清水市
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] Comparison of the chemical properties of a novel amino-linker with various aminomodifications2008
- Author(s)
  小島直
- Organizer
  第35回国際核酸化学シンポジウム
- Place of Presentation
  京都大学
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] Construction of an aminoxy derivative for RNA and DNA labeling2008
- Author(s)
  小松康雄、小島直、小松知志恵、三上暁子、杉野麻衣子、大塚榮子
- Organizer
  第35回核酸化学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] 新規アミノ化試薬の開発と、固相上でのオリゴヌクレオチド修飾反応への応用2008
- Author(s)
  小島直
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜大学
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] 新規アミノ化試薬の開発と, 固相上でのオリゴヌクレオチド修飾反応への応用2008
- Author(s)
  小島直、小松知志恵、三上暁子、杉野麻衣子、大塚榮子、小松康雄
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜県岐阜市
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20710179
[Presentation] Comparison of the chemical properties of a novel amino-linker with various amino modifications2008
- Author(s)
  小島直、小松知志恵、三上暁子、杉野麻衣子、大塚榮子、小松康雄
- Organizer
  第35回核酸化学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-20710179

1. KOMATSU Yasuo (30271670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. UEDE Toshimitsu (00160185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KON Shigeyuki (90344499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Mitani Yasuo (10358103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KURITA RYOJI (50415676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. 大塚榮子 (80028836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 吉岡恭子 (50358321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 冨田峻介 (50726817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 栗之丸隆章 (50769693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. 金賢徹 (70514107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 加藤大 (80533190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 山村昌平 (50432141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. 中村史 (40357661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kojima Naoshi 小島 直

KOJIMA Naoshi 小島 直

Research Projects

Research Products

Co-Researchers

遺伝子検出技術の高感度化に向けた生物発光の利用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

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１細胞単位電気化学発光計測技術によるマーカー分子微量発現がん細胞の超高感度検出

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Epigenome analysis on an array device for single cell / genome

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Novel molecular mechanisms of luminous fireworm

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Building up the bioluminescence molecule on the nucleic acid sequence and its application to gene detection technologyPrincipal Investigator

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Synthesis of novel chemical ligand that selectively bind to the unstabilized base pairs formed in DNAPrincipal Investigator

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分子間相互作用を利用したRNA末端部位標識化試薬の開発Principal Investigator

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非天然型ヌクレオシドの合成と、これを利用した核酸合成酵素認識機構の解析Principal Investigator

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Investigation of regulatory mechanism of homeostasis using functional nucleic acids.

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[Journal Article] Development of gapmer antisense oligonucleotide with deoxyribonucleic guanidine (DNG) modifications2019

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[Journal Article] Immobilization of DNA on Biosensing Devices with Nitrogen Mustard?Modified Linkers2019

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[Journal Article] Sequential Assessment of Multiple Epigenetic Modifications of Cytosine in Whole Genomic DNA by Surface Plasmon Resonance2019

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[Journal Article] Immobilization of DNA with nitrogen mustard?biotin conjugate for global epigenetic analysis2018

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[Journal Article] An alkylating immobilization linker for immunochemical epigenetic assessment2017

Kojima Naoshi 小島直

KOJIMA Naoshi 小島直