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KITAO HIROYUKI  北尾 洋之

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… Alternative Names

KITAO Hiroyuki  北尾 洋之

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Researcher Number 30368617
Other IDs
External Links
Affiliation (Current) 2025: 福岡歯科大学, 口腔歯学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 福岡歯科大学, 口腔歯学部, 教授
2017 – 2022: 九州大学, 薬学研究院, 教授
2015 – 2016: 九州大学, 医学研究院, 准教授
2015: 九州大学, 大学院医学研究科, 准教授
2011 – 2015: 九州大学, 医学(系)研究科(研究院), 准教授 … More
2011 – 2013: 九州大学, 医学研究院, 准教授
2008 – 2010: Kyushu University, 医学研究院, 客員准教授
2009: 京都大学, 放射線生物研究センター, 研究員
2008: Kyushu University, 医学研究院, 寄附講座教員
2007: Kyoto University, 放射線生物研究センター, 助教
2007: 京都大学, 放射線生物研究センター, 研究員
2006: Research Institute for Radiation Biology and Medicine, Postdoctoral Researcher for COE program, 原爆放射線医科学研究所, COE研究員
2004 – 2005: Kawasaki Med Sch, Deptcf Immunol and Mol Genet, Research Associate, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Medium-sized Section 50:Oncology and related fields / Tumor therapeutics
Except Principal Investigator
Digestive surgery / General surgery / Pathological medical chemistry / Biological Sciences / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55020:Digestive surgery-related / Tumor biology / General medical chemistry
Keywords
Principal Investigator
複製ストレス / 抗がん剤 / ゲノム不安定性 / FANCJ / ファンコニ貧血 / 治療誘導性細胞老化 / DNA複製ストレス / BRCA1 / 家族性乳がん / 染色体不安定性 … More / 一本鎖DNA / 1本鎖DNA / ssDNA / ATR / 抗腫瘍効果 / RNA転写複合体 / FancD2 / RNA転写中間体 / M期スキップ / 細胞老化 / がん化学療法 / 抗癌剤 / ロンサーフ(TFTD,TAS-102) / トリフルリジン / FdUrd / MLH1 / 分子腫瘍学 / BRCAI / 家族性乳癌 / 遺伝性疾患 / 相同組換え修復 / DNA2重鎖切断 / DNA鎖間クロスリンク / 遺伝子破壊 / ニワトリB細胞株DT40 / 家族性乳ガン … More
Except Principal Investigator
DNA修復 / 染色体不安定性 / 大腸癌 / I-SceI / DNA repair / 集学的治療 / ゲノム不安定性 / ファンコニ貧血 / トランスレーショナルリサーチ / 細胞・組織 / estrogen receptor / DNA double strand break / TAT配列 / エストロジェン受容体 / homologous recombination / 姉妹染色分体交換 / 遺伝子変異 / MSI / 食道癌 / BUBR1 / 乳癌 / 相同DNA組み換え / DT40細胞 / モノユビキチン化 / ユビキチン化 / 癌の浸潤・転移 / p53機能獲得型変異 / p53機能獲得型変異 / 癌幹細胞化 / エピゲノム異常 / 遺伝子発現プロファイル / p53変異細胞株パネル / 機能獲得型p53変異 / 術後化学療法 / 周術期治療 / NGS解析 / LGR5 / 補助化学療法 / cDNAマクロアレイ / 術後補助療法 / ctDNA / 遺伝子サブタイプ / 遺伝子検査 / ゲノム検査 / ミッドボディ / 酸化ストレス / OGG1 / 細胞質分裂 / heterogeneity / 四倍体細胞 / 癌集学的治療 / 抗腫瘍免疫 / 免疫チェック ポイント阻害剤 / マイクロサテライト不安定性 / 消化管外科 / 免疫チェックポイント阻害剤 / 食道扁平上皮癌 / 創薬 / プロテオーム / Sphere / 化合物ライブラリー / 造血幹細胞 / がん幹細胞 / Type IVcollagen / plasma fibronectin / 腹膜播種 / sphere / シグナル伝達 / 薬剤反応性 / 外科 / 癌 / tamoxifen / non-homologous end joining / DNA二重鎖切断修復 / DNA連鎖切断修復 / protein transduction / I-Sce I / プロテイントランスダクション / TAT配 / I-Scel / DNA二重鎖切断 / sister chromatid exchanges / Fanconi anemia / Rad51 paralogs / DT 40 cells / XRCC3 / Rad52 / Rad51ファミリー / Rad51 / 相同組み換え / 複製後修復 / ジーンターゲティング / 相同組替え / BLMヘリケース / Rad51パラログ / 化学放射線療法 / HLA ClassⅠ / PD-L1 / 腫瘍免疫 / PARP阻害剤 / DNA2重鎖修復 / サブタイプ / 癌抑制遺伝子 / ER陽性乳癌 / APOBEC3B / p53 / 細胞分裂期スピンドルチェックポイント機構 / 炎症 / LINE1 / メチル化 / BRAF / 低侵襲手術 / プロスタグランジン / 炎症性メデイエーター / DNAメチル化 / 遺伝子プロファイル / PAK / 難治性消化管癌 / 染色体分配機構 / 消化管癌 / DNA修復系関連遺伝子 / 5-FU感受性 / 胃十二指腸外科学 / 発がん / PLK1 / Aurora-B / Aurora-A / DNA aneuploidy / スピンドルチェックポイント / GATA-3 / FOXA1 / ホルモン感受性 / ホルモン抵抗性 / ホルモン療法 / ホルモン受容体 / チェックポイント / リン酸化 / チェックポイントキナーゼ / FAコア複合体 / ゲノム安定性 / シスプラチン / FANCI / FANCD2 Less
  • Research Projects

    (25 results)
  • Research Products

    (240 results)
  • Co-Researchers

    (65 People)
  •  Establishment of therapeutic strategies based on the understanding of cancer stemness regulated by gain-of-function mutant p53

    • Principal Investigator
      maehara yoshihiko
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers
  •  The critical role of ATR activation in the process of therapy-induced senescencePrincipal Investigator

    • Principal Investigator
      北尾 洋之
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Fukuoka Dental College
  •  Establishment of new selection system for adjuvant chemotherapy of colorectal cancer

    • Principal Investigator
      OKI Eiji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  RNA involvement in the process of chemotherapy-induced DNA replication stressPrincipal Investigator

    • Principal Investigator
      Kitao Hiroyuki
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Kyushu University
  •  Molecular mechanisms of cytokinesis completion and cell fate decision after cytokinesis failure

    • Principal Investigator
      Iimori Makoto
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Kyushu University
  •  Molecular mechanism of therapy-induced senescence caused by replicative stressPrincipal Investigator

    • Principal Investigator
      Kitao Hiroyuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Kyushu University
  •  Elucidation of molecular mechanisms of and development of combined therapy with immune checkpoint inhibitors for digestive tract cancer

    • Principal Investigator
      SAEKI hiroshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells

    • Principal Investigator
      Maehara Yoshihiko
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Digestive surgery
    • Research Institution
      Fukuoka Dental College
      Kyushu University
  •  Gemonic alteration, molecular subtypes and drug sensitivity in breast cancer

    • Principal Investigator
      Tokunaga Eriko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      National Hospital Organization, Kyushu Cancer Center
      Kyushu University
  •  Investigation of chemoradiation sensitivity based on the DNA repair mechanism in esophageal carcinoma

    • Principal Investigator
      Ito Shuhei
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Novel molecular targeting strategy against chromosomal maintenance factor FANCJPrincipal Investigator

    • Principal Investigator
      KITAO HIROYUKI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyushu University
  •  Chromosomal dynamics and development of novel therapy in gastrointestinal tract cancer

    • Principal Investigator
      Saeki Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Establishment of the new therapy based on inflammatory mediator and DNA methylation in colorectal cancer

    • Principal Investigator
      Oki Eiji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  The analysis of the spindle checkpoint protens and the application to the new molecular targetted therapy for colorectal cancer.

    • Principal Investigator
      Emi Yasunori
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  DNA mismatch repair gene analysis predicts the response to anticancer drug sensitivity in gastrointestinal cancers for tailored therapy.

    • Principal Investigator
      Kakeji Yoshihiro
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kobe University
  •  Molecular mechanisms of hormone sensitivity of hormone receptor-positive breast cancer and their application for individual treatment

    • Principal Investigator
      TOKUNAGA Eriko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kyushu University
  •  A systematic study of the disorders in the spindle assembly checkpoint genes in colorectal cancer and its application to molecular targeted therapy

    • Principal Investigator
      KOHNOE Shunji
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Genomic instability in the absence of FANCJ and its possible contribution to tumorigenesisPrincipal Investigator

    • Principal Investigator
      KITAO Hiroyuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyushu University
  •  Regulation of the ubiquitin system by checkpoint kinases in response to stalled replication forks

    • Principal Investigator
      TAKATA Minoru
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyoto University
  •  Molecular mechanism of large genome deletion induced byDisrupting BRCA1-related gene, FA-J.Principal Investigator

    • Principal Investigator
      KITAO Hiroyuki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyushu University
      Kyoto University
  •  Functional analysis of Fanconi anemia genes that are involved in chromosomal stability and tumor prevention

    • Principal Investigator
      TAKATA Minoru
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
      Hiroshima University
      Kawasaki Medical School
  •  ファンコニ貧血遺伝子FA-D2と家族性乳ガン遺伝子Brca2との相互作用の再検討Principal Investigator

    • Principal Investigator
      北尾 洋之
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Hiroshima University
      Kawasaki Medical School
  •  Induction of single DNA double strand break in animal cell genome and its monitoring methodology

    • Principal Investigator
      TAKATA Minoru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      HIROSHIMA UNIVERSITY
      Kawasaki Medical School
  •  Physical monitoring of repair process of chromosomal double stand break induced by simultaneous nuclear introduction of I-SceI endonuclease

    • Principal Investigator
      TAKATA Minoru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kawasaki Medical School
  •  Functional analysis of genes involved in maintenance of chromosome stability and homologous recombination

    • Principal Investigator
      TAKATA Minoru
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kawasaki Medical School

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] トリフルリジン・チピラシル塩酸塩(TAS-102: TFTD)の抗腫瘍効果における分子機序2016

    • Author(s)
      北尾洋之、松岡和明、飯森真人、徳永えり子、佐伯浩司、沖英次、宮本裕士、馬場秀夫、前原喜彦
    • Total Pages
      7
    • Publisher
      癌と化学療法
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Book] 別冊日本臨床 新領域別症候群シリーズ 「先天代謝異常症候群 第2版(上)」-病因・病態研究、診断・治療の進歩-ファンコニ貧血2012

    • Author(s)
      北尾洋之
    • Total Pages
      688
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Journal Article] The anti-tumor effect of trifluridine via induction of aberrant mitosis is unaffected by mutations modulating p53 activity2023

    • Author(s)
      Wakasa Takeshi、Iimori Makoto、Nonaka Kentaro、Oki Eiji、Maehara Yoshihiko、Kitao Hiroyuki et al.
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2023.08.30.555463

    • Data Source
      KAKENHI-PROJECT-22K19577
  • [Journal Article] Mutational spectrum of TP53 gene correlates with nivolumab treatment efficacy in advanced gastric cancer (TP53MUT study)2023

    • Author(s)
      Ando Koji、Nakamura Yoshiaki、Narita Yukiya、Hara Hiroki、Ohta Takashi、Esaki Taito、Hamamoto Yasuo、Kato Ken、Yamamoto Yoshiyuki、Minashi Keiko、Ohtsubo Koushiro、Izawa Naoki、Kawakami Hisato、Kato Takeshi、Satoh Taroh、Okano Naohiro、Tsuji Akihito、Yamazaki Kentaro、Yoshino Takayuki、Maehara Yoshihiko、Oki Eiji
    • Journal Title

      British Journal of Cancer

      Volume: 129 Issue: 6 Pages: 1032-1039

    • DOI

      10.1038/s41416-023-02378-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19559, KAKENHI-PROJECT-22K19577, KAKENHI-PROJECT-23K24405
  • [Journal Article] Lineage of drug discovery research on fluorinated pyrimidines: chronicle of the achievements accomplished by Professor Setsuro Fujii2023

    • Author(s)
      Maehara Yoshihiko、Oki Eiji、Kitao Hiroyuki、Iimori Makoto、Makino Kunio、Takechi Teiji、Sagara Takeshi、Miyadera Kazutaka、Matsuoka Kazuaki、Wakasa Takeshi、Ochiiwa Hiroaki、et al.
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 28 Issue: 5 Pages: 613-624

    • DOI

      10.1007/s10147-023-02326-w

    • Data Source
      KAKENHI-PROJECT-22K19577
  • [Journal Article] CD44v3,8‐10 is essential for Slug‐dependent <i>vimentin</i> gene expression to acquire TGF‐β1‐induced tumor cell motility2022

    • Author(s)
      Qiu Shichao、Iimori Makoto、Edahiro Keitaro、Fujimoto Yoshiaki、Matsuoka Kazuaki、Oki Eiji、Maehara Yoshihiko、Mori Masaki、Kitao Hiroyuki
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 8 Pages: 2654-2667

    • DOI

      10.1111/cas.15353

    • Data Source
      KAKENHI-PROJECT-22K19577
  • [Journal Article] Lack of impact of the <scp>ALDH2</scp> rs671 variant on breast cancer development in Japanese <scp>BRCA1</scp> /2‐mutation carriers2022

    • Author(s)
      Mori Tomoharu、Takata Minoru et al.
    • Journal Title

      Cancer Medicine

      Volume: 12 Issue: 6 Pages: 6594-6602

    • DOI

      10.1002/cam4.5430

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-22K19577, KAKENHI-PROJECT-21K15362, KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H03748
  • [Journal Article] Detection of trifluridine in tumors of patients with metastatic colorectal cancer treated with trifluridine/tipiracil. Cancer.2020

    • Author(s)
      Fujimoto Y, Nakanishi R, Nukatsuka M, Matsuoka K, Ando K, Wakasa T, Kitao H, Oki E, Maehara Y, Mori M.
    • Journal Title

      Chemother Pharmacol

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05792
  • [Journal Article] DNA replication stress induced by trifluridine determines tumor cell fate according to p53 status2020

    • Author(s)
      Kataoka Yuki、Iimori Makoto、Fujisawa Ryo、Morikawa-Ichinose Tomomi、Niimi Shinichiro、Wakasa Takeshi、Saeki Hiroshi、Oki Eiji、Miura Daisuke、Tsurimoto Toshiki、Maehara Yoshihiko、Kitao Hiroyuki
    • Journal Title

      Molecular Cancer Research

      Volume: - Issue: 9 Pages: 1354-1366

    • DOI

      10.1158/1541-7786.mcr-19-1051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-18K19478
  • [Journal Article] Detection of trifluridine in tumors of patients with metastatic colorectal cancer treated with trifluridine/tipiracil.2020

    • Author(s)
      Fujimoto Yoshiaki, Nakanishi Ryota, Nukatsuka Mamoru, Matsuoka Kazuaki, Ando Koji, Wakasa Takeshi, Kitao Hiroyuki, Oki Eiji, Maehara Yoshihiko, Mori Masaki
    • Journal Title

      Cancer Chemotherapy and Pharmacology

      Volume: - Issue: 6 Pages: 1029-1038

    • DOI

      10.1007/s00280-020-04072-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-18K15282
  • [Journal Article] Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level2019

    • Author(s)
      Kataoka Yuki、Iimori Makoto、Niimi Shinichiro、Tsukihara Hiroshi、Wakasa Takeshi、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko、Kitao Hiroyuki
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 7964-7964

    • DOI

      10.1038/s41598-019-44399-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05792, KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-18K19478
  • [Journal Article] A minimal threshold of FANCJ helicase activity is required for its response to replication stress or double-strand break repair2018

    • Author(s)
      Bharti Sanjay Kumar、Sommers Joshua A、Awate Sanket、Bellani Marina A、Khan Irfan、Bradley Lynda、King Graeme A、Seol Yeonee、Vidhyasagar Venkatasubramanian、Wu Yuliang、Abe Takuye、Kobayashi Koji、Shin-ya Kazuo、Kitao Hiroyuki、Wold Marc S、Branzei Dana、Neuman Keir C、Brosh Robert M
    • Journal Title

      Nucleic Acids Research

      Volume: 46 Issue: 12 Pages: 6238-6256

    • DOI

      10.1093/nar/gky403

    • Data Source
      KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-17H03598
  • [Journal Article] MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites2018

    • Author(s)
      Watanabe Sugiko、Iimori Makoto、Chan David Virya、Hara Eiji、Kitao Hiroyuki、Maehara Yoshihiko
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 10888-10888

    • DOI

      10.1038/s41598-018-29239-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-15H05792
  • [Journal Article] Epithelial Paradox: Clinical Significance of Coexpression of E-cadherin and Vimentin With?Regard to Invasion and Metastasis of Breast?Cancer2018

    • Author(s)
      Yamashita Nami、Tokunaga Eriko、Iimori Makoto、Inoue Yuka、Tanaka Kimihiro、Kitao Hiroyuki、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko
    • Journal Title

      Clinical Breast Cancer

      Volume: 印刷中 Issue: 5 Pages: e1003-e1009

    • DOI

      10.1016/j.clbc.2018.02.002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19899, KAKENHI-PROJECT-18K08576, KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-15H05792
  • [Journal Article] Thymidine Kinase 1 Loss Confers Trifluridine Resistance without Affecting 5-Fluorouracil Metabolism and Cytotoxicity2018

    • Author(s)
      Edahiro Keitaro、Iimori Makoto、Kobunai Takashi、Morikawa-Ichinose Tomomi、Miura Daisuke、Kataoka Yuki、Niimi Shinichiro、Wakasa Takeshi、Saeki Hiroshi、Oki Eiji、Kitao Hiroyuki、Maehara Yoshihiko
    • Journal Title

      Molecular Cancer Research

      Volume: 16 Issue: 10 Pages: 1483-1490

    • DOI

      10.1158/1541-7786.mcr-17-0686

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-16J40073, KAKENHI-PROJECT-16K10502, KAKENHI-PROJECT-15H05792
  • [Journal Article] DNA replication stress and cancer chemotherapy2018

    • Author(s)
      Kitao Hiroyuki、Iimori Makoto、Kataoka Yuki、Wakasa Takeshi、Tokunaga Eriko、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 2 Pages: 264-271

    • DOI

      10.1111/cas.13455

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Journal Article] Activation of the FA pathway mediated by phosphorylation and ubiquitination2017

    • Author(s)
      Ishiai M., Sato K, Tomida J, Kitao H., Kurumizaka H., Takata M.
    • Journal Title

      Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

      Volume: 803-805 Pages: 89-95

    • DOI

      10.1016/j.mrfmmm.2017.05.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-17H03598
  • [Journal Article] Clinical Significance of the Wild Type p53-Induced Phosphatase 1 Expression in Invasive Breast Cancer2017

    • Author(s)
      Inoue Yuka、Yamashita Nami、Kitao Hiroyuki、Tanaka Kimihiro、Saeki Hiroshi、Oki Eiji、Oda Yoshinao、Tokunaga Eriko、Maehara Yoshihiko
    • Journal Title

      Clinical Breast Cancer

      Volume: 印刷中 Issue: 4 Pages: e643-e650

    • DOI

      10.1016/j.clbc.2017.11.008

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-16K19899, KAKENHI-PROJECT-18K08576, KAKENHI-PROJECT-15H05792
  • [Journal Article] Mitotic slippage and the subsequent cell fates after inhibition of Aurora B during tubulin-binding agent?induced mitotic arrest2017

    • Author(s)
      Tsuda Yasuo、Iimori Makoto、Nakashima Yuichiro、Nakanishi Ryota、Ando Koji、Ohgaki Kippei、Kitao Hiroyuki、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 16762-16762

    • DOI

      10.1038/s41598-017-17002-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Journal Article] Monitoring trifluridine incorporation in the peripheral blood mononuclear cells of colorectal cancer patients under trifluridine/tipiracil medication2017

    • Author(s)
      Nakanishi Ryota、Kitao Hiroyuki、Kiniwa Mamoru、Morodomi Yosuke、Iimori Makoto、Kurashige Junji、Sugiyama Masahiko、Nakashima Yuichiro、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 16969-16969

    • DOI

      10.1038/s41598-017-17282-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16564, KAKENHI-PROJECT-17H03598
  • [Journal Article] Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.2016

    • Author(s)
      Tokunaga E, Yamashita N, Tanaka K, Inoue Y, Akiyoshi S, Saeki H, Oki E, Kitao H, Maehara Y.
    • Journal Title

      PLoS One

      Volume: 11 Issue: 12 Pages: e0168090-e0168090

    • DOI

      10.1371/journal.pone.0168090

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
  • [Journal Article] Gastric cancer patients with high PLK1 expression and DNA aneuploidy correlate with poor prognosis.2016

    • Author(s)
      Otsu H,Iimori M, Ando K,Saeki H, Aishima S,Oda Y,Morita M, Matsuo K,Kitao H,Oki E, Maehara Y.
    • Journal Title

      Oncology

      Volume: - Issue: 1 Pages: 31-40

    • DOI

      10.1159/000445952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-15K10125
  • [Journal Article] Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.2016

    • Author(s)
      Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, Oki E, Kitao H, Maehara Y:
    • Journal Title

      Nature Communications

      Volume: [Epub ahead of print] Issue: 1 Pages: 11117-11117

    • DOI

      10.1038/ncomms11117

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25462024, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-15H05792, KAKENHI-PROJECT-26281025, KAKENHI-PROJECT-26430116
  • [Journal Article] Biological and clinical significance of loss of heterozygosity at the INPP4B gene locus in Japanese breast cancer.2016

    • Author(s)
      Tokunaga E, Yamashita N, Kitao H, Tanaka K, Taketani K, Inoue Y, Saeki H, Oki E, Oda Y, Maehara Y.
    • Journal Title

      The Breast

      Volume: 26 Pages: 62-68

    • DOI

      10.1016/j.breast.2015.10.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
  • [Journal Article] The impact of the expression of vimentin and Axl in breast cancer.2016

    • Author(s)
      Tanaka K, Tokunaga E, Inoue Y, Yamashita N, Saeki H, Okano S, Kitao H, P Oki E, Oda Y, Maehara Y.
    • Journal Title

      Clin Breast Cancer

      Volume: 16 Issue: 6 Pages: 520-526

    • DOI

      10.1016/j.clbc.2016.06.015

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
  • [Journal Article] Trifluridine Induces p53-Dependent Sustained G2 Phase Arrest with Its Massive Misincorporation into DNA and Few DNA Strand Breaks2015

    • Author(s)
      Matsuoka K, Iimori M, Niimi S, Tsukihara H, Watanabe S, Kiyonari S, Kiniwa M, Ando K, Tokunaga E, Saeki H, Oki E, Maehara Y, Kitao H.
    • Journal Title

      Molecular Cancer Therapeutics

      Volume: 14 Issue: 4 Pages: 1004-1013

    • DOI

      10.1158/1535-7163.mct-14-0236

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-25460390
  • [Journal Article] The 1,2-diaminocyclohexane carrier ligand in oxaliplatin induces p53-dependent transcriptional repression of factors involved in thymidylate biosynthesis.2015

    • Author(s)
      Kiyonari S, Iimori M, Matsuoka K, Watanabe S, Morikawa-Ichinose T, Miura D, Niimi S, Saeki H, Tokunaga E, Oki E, Morita M, Kadomatsu K, Maehara Y, Kitao H
    • Journal Title

      Mol Cancer Ther

      Volume: 14 Issue: 10 Pages: 2332-42

    • DOI

      10.1158/1535-7163.mct-14-0748

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10125, KAKENHI-PROJECT-25460390, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-26713020
  • [Journal Article] Epigenetic Inactivation of BRCA1 Through Promoter Hypermethylation and Its Clinical Importance in Triple-Negative Breast Cancer.2015

    • Author(s)
      Yamashita N, Tokunaga E, Kitao H, Hitchins M, Inoue Y, Tanaka K, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Oda Y, Saeki H, Oki E, Maehara Y.
    • Journal Title

      Clin Breast Cancer

      Volume: 15 Issue: 6 Pages: 498-504

    • DOI

      10.1016/j.clbc.2015.06.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461949
  • [Journal Article] Discrimination of p53 immunohistochemistry-positive tumors by its staining pattern in gastric cancer.2015

    • Author(s)
      Ando K, Oki E, Saeki H, Yan Z, Tsuda Y, Hidaka G, Kasagi Y, Otsu H, Kawano H, Kitao H, Morita M, Maehara Y.
    • Journal Title

      Cancer Med.

      Volume: 4 Issue: 1 Pages: 75-83

    • DOI

      10.1002/cam4.346

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-15K10125, KAKENHI-PROJECT-15K10127
  • [Journal Article] Mortalin is a prognostic factor of gastric cancer with normal p53 function2014

    • Author(s)
      Ando K, Oki E, Zhao Y, Yoshida A, Kitao H, Saeki H, Kimura Y, Ida S, Morita M, Kusumoto T, Maehara Y.
    • Journal Title

      Gastric Cancer

      Volume: 17(2) Pages: 255-262

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] Oxidative DNA damage in human esophageal cancer: clinicopathological analysis of 8-hydroxydeoxyguanosine and its repair enzyme.2014

    • Author(s)
      Kubo N, Morita M, Nakashima Y, Kitao H, Egashira A, Saeki H, Oki E, Kakeji Y, Oda Y, Maehara Y.
    • Journal Title

      Dis Esophagus.

      Volume: 27 Issue: 3 Pages: 285-293

    • DOI

      10.1111/dote.12107

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-25460390
  • [Journal Article] Aberrations of BUBR1 and TP53 gene mutually associated with chromosomal instability in human colorectal cancer.2014

    • Author(s)
      Zhao Y, Ando K, Oki E, Ikawa-Yoshida A, Ida S, Kimura Y, Saeki H, Kitao H, Morita M, Maehara Y.
    • Journal Title

      Anticancer Res.

      Volume: 34 Pages: 5313-5320

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Journal Article] Mortalin is a prognostic factor of gastric cancer with normal p53 function.2014

    • Author(s)
      Ando K., Oki E., Zhao Y., Yoshida A., Kitao H., Saeki H., Kimura Y., Ida S., Morita M., Kusumoto T., Maehara Y.
    • Journal Title

      Gastric Cancer

      Volume: 17(2) Issue: 2 Pages: 255-262

    • DOI

      10.1007/s10120-013-0279-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-24659614
  • [Journal Article] Chromosomal instability associated with global DNA hypomethylation is associated with the initiation and progression of esophageal squamous cell carcinoma2014

    • Author(s)
      Kawano H, Saeki H, Kitao H, Tsuda Y, Otsu H, Ando K, Ito S, Egashira A, Oki E, Morita M, Oda Y, Maehara Y.
    • Journal Title

      Annals of Surgical Oncology

      Volume: 4 Issue: S4 Pages: 696-702

    • DOI

      10.1245/s10434-014-3818-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-25460390, KAKENHI-PROJECT-25462024
  • [Journal Article] Molecular mechanisms regulating the hormone sensitivity of breast cancer.2014

    • Author(s)
      Tokunaga E1, Hisamatsu Y, Tanaka K, Yamashita N, Saeki H, Oki E, Kitao H, Maehara Y.
    • Journal Title

      Cancer Sci.

      Volume: 105(11) Issue: 11 Pages: 1377-1377

    • DOI

      10.1111/cas.12521

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25861160, KAKENHI-PROJECT-26461949
  • [Journal Article] Contribution of Auroa-A and -B expression to DNA aneuploidy in gastric cancers.2014

    • Author(s)
      Honma K., Nakanishi R., Nakanoko T., Ando K., Saeki H., Oki E., Iimori M., Kitao H., Kakeji Y., Maehara Y.
    • Journal Title

      Surgery Today

      Volume: 44(3) Issue: 3 Pages: 454-461

    • DOI

      10.1007/s00595-013-0581-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24390321
  • [Journal Article] Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer2014

    • Author(s)
      Tokunaga E, Nakashima Y, Yamashita N, Hisamatsu Y, Okada S, Akiyoshi S, Aishima S, Kitao H, Morita M, Maehara Y
    • Journal Title

      Breast Cancer

      Volume: 21 Pages: 341-9

    • Data Source
      KAKENHI-PROJECT-23591896
  • [Journal Article] Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer.2014

    • Author(s)
      Tokunaga E, Nakashima Y, Yamashita N, Hisamatsu Y, Okada S, Akiyoshi S, Aishima S, Kitao H, Morita M, Maehara Y.
    • Journal Title

      Breast Cancer

      Volume: 21 Issue: 3 Pages: 341-349

    • DOI

      10.1007/s12282-012-0398-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591896, KAKENHI-PROJECT-25861160
  • [Journal Article] Contribution of Aurora-A and–B expression to DNA aneuploidy in gastric cancer2014

    • Author(s)
      Honma K, Nakanishi R, Nakanoko T, Ando K, Saeki H, Oki E, Iimori M, Kitao H, Kakeji Y, Maehara Y.
    • Journal Title

      Surg Today

      Volume: 44(3) Pages: 454-461

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer2013

    • Author(s)
      Nakanishi R, Harada J, Tuul M, Zhao Y, Ando K, Saeki H, Oki E, Ohga T, Kitao H, Kakeji Y, Maehara Y.
    • Journal Title

      Int J Clin Oncol

      Volume: 18(6) Pages: 1042-1048

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] Contribution of BubR1 to oxidative stress-induced aneuploidy in p53-deficient cells.2013

    • Author(s)
      Ikawa-Yoshida A., Ando K., Oki E., Saeki H., Kumashiro R., Taketani K., Ida S., Tokunaga E., Kitao H., Morita M., Maehara Y.
    • Journal Title

      Cancer Medicine

      Volume: 2(4) Issue: 4 Pages: 447-456

    • DOI

      10.1002/cam4.101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-24659614, KAKENHI-PROJECT-25462058
  • [Journal Article] Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer.2013

    • Author(s)
      Nakanishi R, Harada J, Tuul M, Zhao Y, Ando K, Saeki H, Oki E, Ohga T, Kitao H, Kakeji Y, Maehara Y
    • Journal Title

      Int J Clin Oncol.

      Volume: 18(6) Issue: 6 Pages: 1042-1048

    • DOI

      10.1007/s10147-012-0501-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Journal Article] Mortalin is a prognostic factor of gastric cancer with normal p53 function.2013

    • Author(s)
      Ando K., Oki E., Zhao Y., Yoshida A., Kitao H., Saeki H., Kimura Y., Ida S., Morita M., Kusumoto T., Maehara Y.
    • Journal Title

      Gastric Cancer

      Volume: 17 Pages: 255-262

    • NAID

      40020216055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462059
  • [Journal Article] Vimentin as a poor prognostic factor for triple-negative breast cancer2013

    • Author(s)
      Yamashita N, Tokunaga E, Kitao H, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Aishima S, Morita M, Maehara Y
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 139 Pages: 739-46

    • Data Source
      KAKENHI-PROJECT-23591896
  • [Journal Article] Congribution of BubR1 to oxidative stress-induced aneuploidy in p53- deficient cells2013

    • Author(s)
      Ikawa-Yoshida A, Ando K, Oki E, Saeki H, Kumashiro R, Taketani K, Ida S, Tokunaga E, Kitao H, Morita M, Maehara Y.
    • Journal Title

      Cancer Medicine

      Volume: 2(4) Pages: 447-456

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] Involvement of ribonucleotide reductase-M1 in 5-fluorouracil induced DNA damage in esophageal cancer cell lines.2013

    • Author(s)
      Aoki Y, Sakogawa K, Hihara J, Emi M, Hamai Y, Kono K, Shi L, Sun J, Kitao H, Ikura T, Niida H, Nakanishi M, Okada M, Tashiro S.
    • Journal Title

      Int J Oncol.

      Volume: 42(6) Issue: 6 Pages: 1951-60

    • DOI

      10.3892/ijo.2013.1899

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22118003, KAKENHI-PLANNED-22131004, KAKENHI-PROJECT-23240124, KAKENHI-PROJECT-23501259, KAKENHI-PROJECT-23510061, KAKENHI-PROJECT-24390072, KAKENHI-PROJECT-24591944, KAKENHI-PROJECT-24659137, KAKENHI-PROJECT-25460390, KAKENHI-PROJECT-25462022, KAKENHI-PROJECT-25640066
  • [Journal Article] Vimentin as a poor prognostic factor for triple-negative breast cancer.2013

    • Author(s)
      Yamashita N, Tokunaga E, Kitao H, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Aishima S, Morita M, Maehara Y.
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 139 Issue: 5 Pages: 739-746

    • DOI

      10.1007/s00432-013-1376-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591896, KAKENHI-PROJECT-25861160
  • [Journal Article] Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance2013

    • Author(s)
      Tuul M
    • Journal Title

      PLoS One

      Volume: 8巻(2号) Issue: 2 Pages: 55361-55361

    • DOI

      10.1371/journal.pone.0055361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24701028, KAKENHI-PROJECT-25460390
  • [Journal Article] The Q Motif of Fanconi Anemia Group J Protein (FANCJ) DNA Helicase Regulates Its Dimerization, DNA Binding, and DNA Repair Function.2012

    • Author(s)
      Wu Y., Sommers JA., Loiland JA., Kitao H., Kuper J., Kisker C., Brosh RM Jr.
    • Journal Title

      J Biol Chem

      Volume: 287(26) Issue: 26 Pages: 21699-716

    • DOI

      10.1074/jbc.m112.351338

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer.2012

    • Author(s)
      Nakanishi R., Harada J., Tuul M., Zhao Y., Ando K., Saeki H., Oki E., Ohga T., Kitao H., Kakeji Y.,
    • Journal Title

      Int J Clin Oncol

      Volume: Nov 29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple negative breast cancers2012

    • Author(s)
      Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y
    • Journal Title

      Breast Cancer

      Volume: 19 Pages: 161-9

    • NAID

      10030981059

    • Data Source
      KAKENHI-PROJECT-23591896
  • [Journal Article] 胃癌における紡錘体形成チェックポイントタンパク質の発現異常とDNA aneuploidy2012

    • Author(s)
      安藤 幸滋、北尾 洋之、飯森 真人、沖  英次、佐伯 浩司、大賀 丈史、掛地 吉弘、辻谷 俊一、鴻江 俊治、前原 喜彦
    • Journal Title

      胃がんperspective

      Volume: 5(1) Pages: 224-224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] PARP and CSB modulate the processing of transcription-mediated DNA strand breaks2012

    • Author(s)
      Sakai A, Sakasai R, Kakeji Y, Kitao H, Maehara Y.
    • Journal Title

      Genes Genetic Systems

      Volume: 87(4) Pages: 265-272

    • NAID

      10031126619

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] 消化器癌におけるDNA aneuploidy の意義2012

    • Author(s)
      安藤 幸滋、趙岩、沖 英次、北尾 洋之、佐伯 浩司、掛地吉 弘、木村 和恵、井田  智、森田  勝、楠本 哲也、前原 喜彦
    • Journal Title

      CYTOMETRY RESEARCH

      Volume: 22(2) Pages: 15-20

    • NAID

      10031026118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity2012

    • Author(s)
      Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yoshinaga K, Saeki H, Morita M, Kakeji Y, Gillespie DA, Yamamoto K, Takata M, Kitao H, Maehara Y.
    • Journal Title

      DNA Repair

      Volume: 11(3) Pages: 247-258

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] FANCJ Expression Predicts the Response to 5-Fluorouracil-Based Chemotherapy in MLH1-Proficient Colorectal Cancer2012

    • Author(s)
      Nakanishi R, Kitao H, Fujinaka Y, Yamashita N, Iimori M, Tokunaga E, Yamashita N, Morita M, Kakeji Y, Maehara Y.
    • Journal Title

      Ann Surg Oncol

      Volume: 19(11) Pages: 3627-3635

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication.2012

    • Author(s)
      Sakasai R., Sakai A., Iimori M., Kiyonari S., Matsuoka K., Kakeji Y., Kitao H., Maehara Y.
    • Journal Title

      Genes Cells

      Volume: 17(12) Issue: 12 Pages: 962-70

    • DOI

      10.1111/gtc.12011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24701028
  • [Journal Article] Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair2012

    • Author(s)
      Koichi Sato. Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Tachiwana, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka
    • Journal Title

      The EMBO Journal

      Volume: 31 Issue: 17 Pages: 3524-3536

    • DOI

      10.1038/emboj.2012.197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J02700, KAKENHI-ORGANIZER-20114001, KAKENHI-PLANNED-20114006, KAKENHI-PROJECT-22370063, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PROJECT-24370071, KAKENHI-PROJECT-24570138, KAKENHI-PROJECT-24870027, KAKENHI-PLANNED-20114005, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23114711, KAKENHI-PUBLICLY-23131505
  • [Journal Article] Loss of Heterozygosity at BRCA1 locus is significantly associated with aggressiveness and poor prognosis in breast cancer2012

    • Author(s)
      Okada S, Tokunaga E, Kitao H, Akiyoshi S, Yamashita N, Saeki H, Oki E, Morita M, Kakeji Y, Maehara Y
    • Journal Title

      Ann Surg Oncol

      Volume: 19 Pages: 1499-507

    • Data Source
      KAKENHI-PROJECT-23591896
  • [Journal Article] Loss of Heterozygosity at BRCA1 Locus Is Significantly Associated with Aggressiveness and Poor Prognosis in Breast Cancer.2012

    • Author(s)
      Okada S, Tokunaga E, Kitao H, Akiyoshi S, Yamashita N, Saeki H, Oki E, Morita M, Kakeji Y, Maehara Y.
    • Journal Title

      Ann Surg Oncol.

      Volume: 19 Pages: 1499-507

    • Data Source
      KAKENHI-PROJECT-23591896
  • [Journal Article] FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer2012

    • Author(s)
      Nakanishi, et al
    • Journal Title

      Annals of Surgical Oncology

      Volume: (In press) Issue: 11 Pages: 3627-35

    • DOI

      10.1245/s10434-012-2349-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590338, KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24591966
  • [Journal Article] PARP and CSB modulate the processing of transcription-mediated DNA strand breaks.2012

    • Author(s)
      Sakai A., Sakasai R., Kakeji Y., Kitao H., Maehara Y.
    • Journal Title

      Genes Genetic Systems

      Volume: 87(4) Pages: 265-72

    • NAID

      10031126619

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] 胃癌における紡錘体形成チェックポイントタンパク質の発現異常とDNA aneuploidy2012

    • Author(s)
      安藤幸滋、北尾洋之、飯森真人、沖英次、佐伯浩司、大賀丈史、掛地吉弘、辻谷俊一、鴻江俊治、前原喜彦
    • Journal Title

      胃がんperspective

      Volume: 5(1) Pages: 24-32

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication2012

    • Author(s)
      Sakasai R, Sakai A, Iimori M, Kiyonari S, Matsuoka K, Kakeji Y, Kitao H, Maehara Y.
    • Journal Title

      Genes Cells

      Volume: 17(12) Pages: 962-970

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers.2012

    • Author(s)
      Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y.
    • Journal Title

      Breast Cancer.

      Volume: 19 Pages: 161-9

    • NAID

      10030981059

    • Data Source
      KAKENHI-PROJECT-23591896
  • [Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers.2011

    • Author(s)
      Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y.
    • Journal Title

      Breast Cancer

      Volume: (In press)

    • NAID

      10030981059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] FancJ/Brip1 helicase protects against genomic losses and gains invertebrate cells2011

    • Author(s)
      Kitao, et al
    • Journal Title

      Genes to Cells

      Volume: 16 Issue: 6 Pages: 717-724

    • DOI

      10.1111/j.1365-2443.2011.01523.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590338, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
  • [Journal Article] Fanconi anemia : a disorder defective in the DNA damage response2011

    • Author(s)
      Kitao, Takata
    • Journal Title

      International Journal of Hematology

      Volume: 93 Issue: 4 Pages: 417-424

    • DOI

      10.1007/s12185-011-0777-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590338, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
  • [Journal Article] Evaluation of homologous recombinational repair in chicken Blymphoma cell line, DT402011

    • Author(s)
      Kitao, et al
    • Journal Title

      Methods in Molecular Biology

      Volume: 745 Pages: 293-309

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] Fanconi anemia : a disorder defective in the DNA damage response.2011

    • Author(s)
      Kitao H, Takata M
    • Journal Title

      Int J Hematology

      Volume: (In press)

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer2010

    • Author(s)
      Ando K, Kakeji Y, Kitao H, Iimori M, Zhao Y, Yoshida R, Oki E, Yoshinaga K, Matumoto T, Morita M, Sakaguchi Y, Maehara Y
    • Journal Title

      Cancer Science Epub

    • NAID

      10026589263

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers2010

    • Author(s)
      Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y
    • Journal Title

      Breast Cancer

    • NAID

      10030981059

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes.2010

    • Author(s)
      Wu Y, Sommers JA, Suhasini AN, Leonard T, Deakyne JS, Mazin AV, Shin-Ya K, Kitao H, Brosh RM Jr.
    • Journal Title

      Blood

      Volume: 116 Pages: 3780-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer2010

    • Author(s)
      Tokunaga E, Okada S, Kitao H, Shiotani S, Saeki H, Endo K, Morita M, Kakeji Y, Maehara Y.
    • Journal Title

      Breast Cancer Epub

    • NAID

      10029407629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] The Fanconi anemia pathway : Insights from somatic cell genetics using DT40 cell line. Invited review.2009

    • Author(s)
      Takata M, Ishiai M, Kitao H
    • Journal Title

      Mutation Research Fanconi anemia special Issue (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Journal Article] Insights from somatic cell genetics using DT40 cellline. Invited review2009

    • Author(s)
      Takata M, Ishiai M, Kitao H., et.al.
    • Journal Title

      Mutation Research Fanconi anemia Special Issue(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] TheFanconi anemia pathway: Insights from somatic cell genetics using DT40 cell line.2009

    • Author(s)
      Takata M., Ishiai M., Kitao H.
    • Journal Title

      Invited review. Mutat. Res. 668

      Pages: 92-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] The Fanconi anemia pathway : Insights from somatic cell genetics using DT40 cell line.2009

    • Author(s)
      Takata M, Ishiai M, Kitao H
    • Journal Title

      Mutat Res 668

      Pages: 92-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] ファンコニ貧血とDNA損傷応答ネットワーク2009

    • Author(s)
      松下暢子、北尾洋之、石合正道、高田穣
    • Journal Title

      蛋白質核酸酵素 54

      Pages: 580-585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] The Fanconi anemia pathway : insights from somatic cell genetics using DT40 cell line2009

    • Author(s)
      Takata M, Iahiai M, Kitao H.
    • Journal Title

      Mutation Research 668

      Pages: 92-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] ファンコニ貧血とゲノム不安定性2009

    • Author(s)
      北尾洋之、藤中良彦、久保信英、中ノ子智徳、吉永敬士、徳永えり子、佐伯浩司、遠藤和也、森田勝、掛地吉弘、前原喜彦
    • Journal Title

      福岡医学雑誌 99

      Pages: 115-122

    • NAID

      120000981513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR muation2008

    • Author(s)
      Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M
    • Journal Title

      Cancer Science 98

      Pages: 357-363

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway2008

    • Author(s)
      Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, Saberi A, Kinoshita E, Kinoshita Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M.
    • Journal Title

      Nat Struct Mol Biol 15(11)

      Pages: 1138-46

    • Data Source
      KAKENHI-PROJECT-19390087
  • [Journal Article] FANCI phosphorylation functions as a molecular switchto turn on the Fanconi anemia pathway2008

    • Author(s)
      Ishiai Kitao H, Smogorzewska A, Tomida J, Kinomura A, et.al.
    • Journal Title

      Nat Struct Mol Biol 15

      Pages: 1138-1146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion2008

    • Author(s)
      Kitao H, Kimura M, Yamamoto K, Seo H, Namikoshi K, Agata Y, Ohta K, Takata M.
    • Journal Title

      Int Immunol 20(2)

      Pages: 277-84

    • NAID

      10021239538

    • Data Source
      KAKENHI-PROJECT-19390087
  • [Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway2008

    • Author(s)
      Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, Saberi A, Kinoshita E, Kinoshita Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M
    • Journal Title

      Nature Structural and Molecular Biology 15

      Pages: 1138-1146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.2008

    • Author(s)
      Ishiai M, Kitao H, Elledge SJ, Takata M., et al
    • Journal Title

      Nat Struct Mol Biol. 15

      Pages: 1138-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.2008

    • Author(s)
      Kitao H., Kimura M., Yamamoto K., Seo H., Namikoshi K., Agata Y., Ohta K., Takata M.
    • Journal Title

      Int. Immunol. 20

      Pages: 277-284

    • NAID

      10021239538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Detection of phosphorylation on large proteins by western blotting using Phos-tag containing gel.2008

    • Author(s)
      Tomida J., Kitao H., Kinoshita E., Takata., M.
    • Journal Title

      Nature Protocols 232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in immunoglobulin gene conversion.2008

    • Author(s)
      Kitao, H., Kimura, M., Yamamoto, K., Seo, H., Namikoshi, K., Agata, Y., Ohta, K., and Takata, M.
    • Journal Title

      International Immunology 20

      Pages: 277-284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.2008

    • Author(s)
      Kitao H, et. al.
    • Journal Title

      Int Immunology 20

      Pages: 277-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion2008

    • Author(s)
      Kitao H, Kimura M, Yamamoto K, Seo H, Namikoshi K, Agata Y, Ohta K, Takata M
    • Journal Title

      International Immunology 20

      Pages: 277-284

    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.2008

    • Author(s)
      Kitao H, et. al.
    • Journal Title

      Int Immunology 20

      Pages: 277-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway2008

    • Author(s)
      Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, SaberiA, Kinoshita E, Kinoshita-Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M
    • Journal Title

      Nature Structural and Molecular Biology 15

      Pages: 1138-1146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.2008

    • Author(s)
      Ishiai M., Kitao H., Smogorzewska A., Tomida J., Kinomura A., Uchida E., Saberi A., Kinoshita E., Kinoshita-Kikuta E., Koike T., Tashiro S., Elledge S.J., Takata M.
    • Journal Title

      Nat. Struc. Mol. Biol. 15

      Pages: 1138-1146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] ファンコニ貧血とゲノム不安定2008

    • Author(s)
      北尾洋之、藤中良彦、久保信英、中ノ子智徳、吉永士、徳永えり子、佐伯浩司、遠藤和也、森田勝、掛地吉弘、前原喜彦
    • Journal Title

      福岡医学雑誌 99

      Pages: 115-122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non Small Cell Lung Cancer Cell Line.2007

    • Author(s)
      Ogino A., Kitao H., A., Ishiai M., Kozuki T., Takigawa N., Hirano S., Uchida Takata M., Kiura K., Tanimoto M.
    • Journal Title

      Cancer Res. 67

      Pages: 7807-7014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] ファンコニ貧血の分子機構2007

    • Author(s)
      北尾洋之, 高田穣
    • Journal Title

      最新医学 62・2

      Pages: 112-117

    • NAID

      40015288565

    • Data Source
      KAKENHI-PROJECT-17790218
  • [Journal Article] Emergence of epidermal growth factor receptor T790M mutation during chronicexposure to gefitinib in a non small cell lung cancer cell line.2007

    • Author(s)
      Ogino, A., Kitao, H., Hirano, S., Uchida, A., Ishiai, M., Kozuki, T., Takigawa, N., Takata, M., Kiura, K., and Tanimoto, M.
    • Journal Title

      Cancer Research 67

      Pages: 7807-7814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] A requirement of FancL and FancD2 monoubiquitination in DNA repair.2007

    • Author(s)
      Seki S., Ohzeki M., Uchida A., Hirano S., Matsushita N., Kitao H., Oda T., Yamashita T., Kashihara N., Tsubahara A., Takata M., Ishiai M.
    • Journal Title

      Genes Cells 12

      Pages: 299-310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation.2007

    • Author(s)
      Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M.
    • Journal Title

      Cancer Sci. 98(3)

      Pages: 357-63

    • NAID

      10019481589

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590279
  • [Journal Article] Fanconi Anemia : genetic analysis of a human disease using chicken system2007

    • Author(s)
      Takata M, Kitao H, Ishiai M
    • Journal Title

      Cytogenetic and Genome Research 117

      Pages: 346-351

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] genetic analysis of a human disease using chicken system.2007

    • Author(s)
      Takata M, Kitao H, Ishiai M. Fanconianemia
    • Journal Title

      Cytogenet Genome Res. 117

      Pages: 346-351

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] A requirement of FancL and FancD2 monoubiquitination in DNA repair.2007

    • Author(s)
      Seki S, Ohzeki M, Uchida A, Hirano S, Matsushita N, Kitao H, Oda T, Yamashita T, Kashihara N, Tsubahara A, Takata M, Ishiai M.
    • Journal Title

      Genes Cells. 12(3)

      Pages: 299-310

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590279
  • [Journal Article] ファンコニ貧血の分子機構2007

    • Author(s)
      北尾洋之、高田穣
    • Journal Title

      最新医学 62

      Pages: 112-117

    • NAID

      40015288565

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non Small Cell Lung Cancer Cell Line2007

    • Author(s)
      Ogino A, Kitao H, Hirano S, Uchida A, Ishiai M, Kozuki T, Takigawa N, Takata M, Kiura K, Tanimoto M
    • Journal Title

      Cancer Res. 67(16)

      Pages: 7807-14

    • Data Source
      KAKENHI-PROJECT-19390087
  • [Journal Article] Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non small cell lung cancer cell line2007

    • Author(s)
      Ogino A, Kitao H, Hirano S, Uchida A, Ishiai M, Kozuki T, Takigawa N, Takata M, Kiura K, Tanimoto M.
    • Journal Title

      Cancer Research 67

      Pages: 7807-7814

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] A requirement of FancL and FancD2 monoubiquitination in DNA repair2007

    • Author(s)
      Seki S, Ohzeki M, Uchida A, Hirano S, Matsushita N, Kitao H, Oda T, Yamashita T, Kashihara N, Tsubahara A, Takata M, Ishiai M
    • Journal Title

      Genes to Cells 12

      Pages: 299-310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006

    • Author(s)
      Kitao H., Yamamoto K., Matsushita N., Ohzeki M., Ishiai M., Takata M.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 21312-21320

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Functional interplay between BRCA2/FANCDI and FANCC in DNA repair.2006

    • Author(s)
      Kitao H, Yamanioto K. et al.
    • Journal Title

      Journal of Biological Chemistry 281・302

      Pages: 21312-21320

    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006

    • Author(s)
      Kitao H, Yamamoto K, etal.
    • Journal Title

      Journal of Biological Chemistry 281・301

      Pages: 21312-21320

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590279
  • [Journal Article] Functional interplay between BRCA2/FancD2 and FancC in DNA repair.2006

    • Author(s)
      Kitao H, Yamamoto K, et al.
    • Journal Title

      Journal of Biological Chemistry 281・30

      Pages: 21312-21320

    • Data Source
      KAKENHI-PROJECT-17790218
  • [Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006

    • Author(s)
      Kitao H, Yamamoto K, Matsushita N, Ohzeki M, Ishiai M, Takata M.
    • Journal Title

      J Biol Chem. 281(30)

      Pages: 21312-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590279
  • [Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006

    • Author(s)
      Kitao H, Yamamoto K, et al.
    • Journal Title

      Journal of Biological Chemistry 281・302

      Pages: 21312-21320

    • Data Source
      KAKENHI-PROJECT-17590279
  • [Journal Article] DNA修復における家族性乳ガン遺伝子BRCA2とファンコニ貧血経路との機能的連携2006

    • Author(s)
      北尾洋之
    • Journal Title

      放射線生物研究 41・2

      Pages: 137-153

    • NAID

      40007359881

    • Data Source
      KAKENHI-PROJECT-17790218
  • [Journal Article] A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair.2005

    • Author(s)
      Matsushita N., Kitao H., Ishiai M., Nagashima N., Hirano S., Okawa K., Ohta T., Yu D.S., McHugh P.J., Hickson I.D., Venkitaraman A.R., Kurumizaka H., Takata M.
    • Journal Title

      Mol. Cell 19

      Pages: 841-847

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Journal Article] A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair.2005

    • Author(s)
      Matsushita N, Kitao H, Ishiai M, Nagashima N, Hirano S, Okawa K, Ohta T, Yu DS, McHugh PJ, Hickson ID, Venkitaraman AR, Kurumizaka H, Takata M.
    • Journal Title

      Mol Cell. 19(6)

      Pages: 841-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590279
  • [Journal Article] Copy-neutral loss of heterozygosity at the p53 locus in carcinogenesis of esophageal squamous cell carcinomas associated with p53 mutations

    • Author(s)
      Saeki H, Kitao H, Yoshinaga K, Nakanoko T, Kubo N, Kakeji Y, Morita M, Maehara Y.
    • Journal Title

      Clinical Cancer Research

      Volume: 17(7) Pages: 1731-40

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes

    • Author(s)
      Wu Y, Sommers JA, Suhasini AN, Leonard T, Deakyne JS, Mazin AV, Shin-Ya K, Kitao H, Brosh RM Jr
    • Journal Title

      Blood

      Volume: 116(19) Pages: 3780-91

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] Maehara Y. FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer

    • Author(s)
      Nakanishi R, Kitao H, Fujinaka Y, Yamashita N, Iimori M, Tokunaga E, Yamashita N, Morita M, Kakeji Y
    • Journal Title

      Annals of Surgical Oncology(2012) in press.

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] Fanconi anemia : a disorder defective in the DNA damage response

    • Author(s)
      Kitao H, Takata M
    • Journal Title

      International Journalof Hematology

      Volume: 4 Pages: 417-24

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] 消化器癌におけるDNA aneuploidyの意義

    • Author(s)
      安藤幸滋、趙岩、沖英次、北尾洋之、佐伯浩司、掛地吉弘、木村和恵、井田智、森田勝、楠本哲也、前原喜彦
    • Journal Title

      CYTOMETRY RESEARCH

      Volume: 22(2) Pages: 15-20

    • NAID

      10031026118

    • Data Source
      KAKENHI-PROJECT-23591964
  • [Journal Article] Maehara Y. ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity

    • Author(s)
      Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yoshinaga K, Saeki H, Morita M, Kakeji Y, Gillespie DA, Yamamoto K, Takata M, Kitao H
    • Journal Title

      DNA Repair(Amst)

      Volume: 11(3) Pages: 247-58

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer

    • Author(s)
      Ando K, Kakeji Y, Kitao H, Iimori M, Zhao Y, Yoshida R, Oki E, Yoshinaga K, Matumoto T, Morita M, Sakaguchi Y, Maehara Y
    • Journal Title

      Cancer Science

      Volume: 101(3) Pages: 639-45

    • NAID

      10026589263

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer

    • Author(s)
      Tokunaga E, Okada S, Kitao H, Shiotani S, Saeki H, Endo K, Morita M, Kakeji Y, Maehara Y
    • Journal Title

      Breast Cancer

      Volume: 18(2) Pages: 120-3

    • NAID

      10029407629

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] Maehara Y. FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer

    • Author(s)
      Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yoshinaga K, Saeki H, Morita M, Kakeji Y, Gillespie DA, Yamamoto K, Takata M, Kitao H
    • Journal Title

      Annals of Surgical Oncology(2012) in press

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells

    • Author(s)
      Kitao H, Nanda I, Sugino RP, Kinomura A, Yamazoe M, Arakawa H, Schmid M, Innan H, Hiom K, Takata M
    • Journal Title

      Genes to Cells(2011)

      Volume: 16(6) Pages: 714-27

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] Evaluation of homologous recombinational repair in chicken B lymphoma cell line

    • Author(s)
      Kitao H, Hirano S, Takata M.
    • Journal Title

      DT40. Methods Mol Biol

      Volume: 745

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Journal Article] The Fanconi anemia pathway : insights from somatic cell genetics using DT40 cell line

    • Author(s)
      Takata M, Ishiai M, Kitao H
    • Journal Title

      Mutation Research

      Volume: 668(1-2) Pages: 92-102

    • Data Source
      KAKENHI-PROJECT-21590338
  • [Patent] 検出剤、該検出剤を含むキット、被験試料中のDNAに取り込まれたトリフルリジンを検出する方法およびトリフルリジンまたはトリフルリジンを含む抗悪性腫瘍剤の抗腫瘍効果を判定する方法2015

    • Inventor(s)
      北尾洋之、諸富洋介、木庭守、前原喜彦
    • Industrial Property Rights Holder
      北尾洋之、諸富洋介、木庭守、前原喜彦
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25460390
  • [Presentation] p53機能欠損細胞におけるトリフルリジン誘導性DNA複製ストレスによる細胞毒性効果のメカニズム Mechanisms of cytotoxicity of trifluridine-induced DNA replication stress in p53 deficient cells2024

    • Author(s)
      飯森真人,若狹武司,野中謙太朗,菊竹智恵,須山幹太,小武内尚,松岡和明,沖英次,前原喜彦,北尾洋之
    • Organizer
      第83回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19577
  • [Presentation] The significance of ATR as a therapeutic target in combination with DNA replication stress-inducing drugs2023

    • Author(s)
      北尾洋之、野中謙太朗、飯森真人、沖英次
    • Organizer
      19th Ataxia Telagiectasia Workshop
    • Data Source
      KAKENHI-PROJECT-22K19577
  • [Presentation] The significance of ATR as a therapeutic target in combination with DNA replication stress-inducing drugs2023

    • Author(s)
      北尾洋之、野中謙太朗、飯森真人、沖英次
    • Organizer
      19th Ataxia Telagiectasia Workshop
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24030
  • [Presentation] DNA複製ストレス誘導性抗がん剤との併用における治療標的としてのATR制御の意義2022

    • Author(s)
      野中謙太朗、飯森真人、北尾洋之
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K24030
  • [Presentation] DNA複製ストレス誘導性抗がん剤との併用における治療標的としてのATR制御の意義2022

    • Author(s)
      野中謙太朗、飯森真人、北尾洋之
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19577
  • [Presentation] p53機能欠損細胞におけるトリフルリジン誘導性DNA複製ストレスによる細胞毒性効果のメカニズム2022

    • Author(s)
      飯森真人、若狹武司、野中謙太朗、菊竹千恵、須山幹太、小武内尚、松岡和明、沖英次、前原喜彦、北尾洋之
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K24030
  • [Presentation] DNA複製ストレス誘導性抗がん剤との併用における治療標的としてのATR制御の意義2022

    • Author(s)
      飯森真人、野中謙太朗、北尾洋之
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K24030
  • [Presentation] DNA複製ストレス誘導性抗がん剤との併用における治療標的としてのATR制御の意義2022

    • Author(s)
      飯森真人、野中謙太朗、北尾洋之
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K19577
  • [Presentation] p53機能欠損細胞におけるトリフルリジン誘導性DNA複製ストレスによる細胞毒性効果のメカニズム2022

    • Author(s)
      飯森真人、若狹武司、野中謙太朗、菊竹千恵、須山幹太、小武内尚、松岡和明、沖英次、前原喜彦、北尾洋之
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19577
  • [Presentation] Tracing trifluridine in the DNA using anti-BrdU antibodies2019

    • Author(s)
      北尾洋之、藤本禎明、中西良太、糠塚守、松岡和明、武知貞士、若狹武司、飯森真人、森正樹
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19478
  • [Presentation] トリフルリジン誘導性細胞老化とDNA複製ストレスとの関連2019

    • Author(s)
      北尾洋之、片岡裕貴、飯森真人、若狹武司、藤澤遼、釣本敏樹、松岡和明、沖英次、佐伯浩司、前原喜彦、森正樹
    • Organizer
      第23回日本がん分子標的治療学会
    • Data Source
      KAKENHI-PROJECT-18K19478
  • [Presentation] Cell fate decision according to p53 status in response to nucleoside analog-induced DNA replication stress2018

    • Author(s)
      Hiroyuki Kitao
    • Organizer
      Gordon Research Conference-Mutagenesis
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Presentation] Cell fate decision according to p53 status in response to nucleoside analog-induced DNA replication stress2018

    • Author(s)
      Hiroyuki Kitao
    • Organizer
      Gordon Research Conference-Mutagenesis
    • Data Source
      KAKENHI-PROJECT-18K19478
  • [Presentation] Cell fate decision according to p53 status in response to nucleoside analog-induced DNA replication stress2018

    • Author(s)
      Hiroyuki Kitao
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Presentation] Cell fate decision according to p53 status in response to nucleoside analog-induced DNA replication stress2018

    • Author(s)
      Hiroyuki Kitao
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K19478
  • [Presentation] The mechanism of tumor cell fate decision by an antitumor nucleoside analogue, trifluridine2018

    • Author(s)
      Hiroyuki Kitao
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K19478
  • [Presentation] The mechanism of tumor cell fate decision by an antitumor nucleoside analogue, trifluridine2018

    • Author(s)
      Hiroyuki KItao
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Presentation] トリフルリジン誘導性DNA複製ストレスががん細胞の運命に及ぼす影響2017

    • Author(s)
      北尾洋之、片岡裕貴、飯森真人、藤澤遼、 釣本敏樹、一瀬智美、三浦大典、松岡和明、沖英次、佐伯浩司、前原喜彦
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Presentation] トリフルリジン・チピラシルによる治療効果の基礎・臨床での評価2017

    • Author(s)
      北尾 洋之、飯森真人、中西良太、佐伯浩司、沖英次、前原喜彦
    • Organizer
      第35回日本ヒト細胞学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Presentation] Replicative stress in the induction of p53-dictated cytotoxicity by an antitumor nucleoside analogue, trifluridine.2017

    • Author(s)
      北尾洋之、片岡裕貴、飯森真人、藤澤遼、 釣本敏樹、一瀬智美、三浦大典、松岡和明、沖英次、佐伯浩司、前原喜彦
    • Organizer
      29th Fanconi Anemia Research Fund Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Presentation] ヌクレオチドアナログ誘導性DNA複製ストレスとp53を介した細胞運命2017

    • Author(s)
      北尾洋之、飯森真人、片岡裕貴、藤澤遼、釣本敏樹、一瀬智美、三浦大典、若狹武司、松岡和明、佐伯浩司、沖英次、前原喜彦
    • Organizer
      第40回日本分子生物学会総会
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Presentation] トリフルリジン誘導性DNA複製ストレスががん細胞の運命に及ぼす影響2017

    • Author(s)
      北尾洋之、片岡裕貴、飯森真人、藤澤遼、 釣本敏樹、一瀬智美、三浦大典、松岡和明、沖英次、佐伯浩司、前原喜彦
    • Organizer
      第21回日本がん分子標的治療学会
    • Data Source
      KAKENHI-PROJECT-17H03598
  • [Presentation] Clinical impact of the expression of polymeraseθ in breast cancer2016

    • Author(s)
      Eriko Tokunaga, Yuka Inoue, Nami Yamashita, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26461949
  • [Presentation] Clinical impact of the expression of APOBEC3B in breast cancer2015

    • Author(s)
      Eriko Tokunaga, Nami Yamashita, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-26461949
  • [Presentation] 食道扁平上皮癌におけるMTH1発現のバイオマーカーとしての意義2015

    • Author(s)
      佐伯浩司、秋山真吾、北尾洋之、西村 章、工藤健介、中司 悠、田尻裕匡、堤 智崇、由茅隆文、笠木勇太、杉山雅彦、中島雄一郎、大垣吉平、園田英人、沖 英次、前原喜彦
    • Organizer
      第26回日本消化器癌発生学会総会
    • Place of Presentation
      鳥取
    • Year and Date
      2015-11-20
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] The 1,2-diaminocyclohexane carrier ligand in oxaliplatin induces p53-dependent transcriptional repression of factors involved in thymidylate biosynthesis2015

    • Author(s)
      北尾洋之
    • Organizer
      27th AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
    • Place of Presentation
      Hynes Convention Center, Boston, MA, USA
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460390
  • [Presentation] Cellular response to a fluorinated thymidine analogue trifluridine, a key component of the novel oral antitumor drug TAS-102.2015

    • Author(s)
      Kitao H., Matsuoka K., Iimori M., Niimi S., Watanabe S., Kiniwa M,, Maehara Y.
    • Organizer
      Gordon Research Conference on Nucleosides, Nucleotides and Oligonucleotides, Newport, Rhode Island
    • Place of Presentation
      USA
    • Year and Date
      2015-06-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] 新規経口ヌクレオシド型抗腫瘍薬「ロンサーフ」の作用機序2015

    • Author(s)
      北尾 洋之
    • Organizer
      九州大学先端融合医療レドックスナビ研究拠点若手研究者主催シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2015-01-27
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] Cellular response to a fluorinated thymidine analogue trifluridine, a key component of the novel oral antitumor drug TAS-1022015

    • Author(s)
      北尾洋之
    • Organizer
      Gordon Research Conference on Nucleosides, Nucleotides and Oligonucleotides
    • Place of Presentation
      Salva Regina University, Newport, RI, USA
    • Year and Date
      2015-06-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460390
  • [Presentation] 新規経口ヌクレオシド系抗悪性腫瘍剤TAS-102の抗がん作用機序解析2015

    • Author(s)
      北尾 洋之、松岡 和明、新美晋一郎、飯森 真人、渡邉すぎ子、 木庭  守、佐伯 浩司、沖  英次、前原 喜彦
    • Organizer
      第19回日本がん分子標的治療学会学術集会
    • Place of Presentation
      松山
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-15H05792
  • [Presentation] Trifluridine induces p53-dependent sustained G2 phase arrest with its massive misincorporation into DNA and few DNA strand breaks2015

    • Author(s)
      Kazuaki Matsuoka, Hiroyuki Kitao
    • Organizer
      American Association of Cancer Research (AACR) Annual Meeting 2015
    • Place of Presentation
      Philadelphia, PA
    • Year and Date
      2015-04-20
    • Data Source
      KAKENHI-PROJECT-25460390
  • [Presentation] 食道扁平上皮癌におけるMTH1発現のバイオマーカーとしての意義2015

    • Author(s)
      佐伯 浩司、秋山 真吾、北尾 洋之、西村  章、工藤 健介、 中司  悠、田尻 裕匡、堤  智崇、由茅 隆文、笠木 勇太、 杉山 雅彦、中島雄一郎、大垣 吉平、園田 英人、沖  英次、 前原 喜彦
    • Organizer
      第26回日本消化器癌発生学会総会
    • Place of Presentation
      米子
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-15H05792
  • [Presentation] トリフルリジンはDNAに取り込まれ、p53依存的なG2期停止を引き起こす2015

    • Author(s)
      北尾 洋之、松岡 和明、飯森 真人、新美晋一郎、渡邊すぎ子、 佐伯 浩司、沖  英次、前原 喜彦
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H05792
  • [Presentation] Cellular response to a fluorinated thymidine analogue trifluridine, a key component of the novel oral antitumor drug TAS-1022015

    • Author(s)
      Kitao H., Matsuoka K., Iimori M., Niimi S., Watanabe S.Kiniwa M., Maehara Y.
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Rockport, RI, USA
    • Year and Date
      2015-06-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05792
  • [Presentation] The 1,2-diaminocyclohexane carrier ligand in oxaliplatin induces p53-dependent transcriptional repression of factors involved in thymidylate biosynthesis.2015

    • Author(s)
      Kitao H., Kiyonari S., Iimori M., Matsuoka K., Morikawa-Ichinose T., Miura D., Niimi S., Saeki H., Oki E., Maehara Y.
    • Organizer
      AACR-NCI-EORTC International Conference &#8211; Molecular Targets and Cancer Therapeutics
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05792
  • [Presentation] The 1,2-diaminocyclohexane carrier ligand in oxaliplatin induces p53-dependent transcriptional repression of factors involved in thymidylate biosynthesis2015

    • Author(s)
      Kitao H., Kiyonari S, Iimori M, Matsuoka K, Morikawa-Ichinose T, Miura D, Niimi S, Saeki H, Oki E, Maehara Y.
    • Organizer
      27th AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Boston, Massachusetts
    • Place of Presentation
      USA
    • Year and Date
      2015-11-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] 新規経口ヌクレオシド型抗腫瘍薬「ロンサーフ」の作用機序2015

    • Author(s)
      北尾 洋之
    • Organizer
      九州大学先端融合医療レドックスナビ研究拠点若手研究者主催シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2015-01-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460390
  • [Presentation] Analysis of KRAS/NRAS, PI3CA and BRAF mutations in the phase 2 KSCC0901 study of cetuximab + s-1 as 3rd-line treatment for metastatic colorectal cancer in Japanese patients2014

    • Author(s)
      Yasunori Emi, Eiji Oki, Hiroshi Saeki, Hiroyuki Kitao, Hironori Samura, Takao Takahashi, Terumitsu Sawai, Yoshito Akagi, Akihito Tsuji, Susumu Eguchi, Kazuhiro Yoshida, Hideo Baba, Yutaka Ogata, Shoji Natsugoe, Mototugu Shimokawa, Yoshihiko Maehara
    • Organizer
      ASCO-GI
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-25462059
  • [Presentation] Aurora BおよびCDK1による微小管結合因子EB2の制御機構2013

    • Author(s)
      飯森 真人、北尾 洋之、渡邊すぎ子、前原 喜彦
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] Subtype specific chromosomal aberrations in breast cancer2013

    • Author(s)
      Eriko Tokunaga, Nami Yamashita, Kimihiro Tanaka, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Masaru Morita, Yoshihiko Maehara
    • Organizer
      San Antonio Breast Cancer Symposium 2013
    • Place of Presentation
      San Antonio
    • Data Source
      KAKENHI-PROJECT-23591896
  • [Presentation] Trifluorothymidine induces p53-dependent sustained G2 arrest without extensive DNA strand-breaks2013

    • Author(s)
      Kazuaki Matsuoka, Makoto Iimori, Hiroshi Tsukihara, Shinichi Kiyonari, Sugiko Watanabe, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
    • Organizer
      第36回日本分子生物学会総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25460390
  • [Presentation] Subtype specific chromosomal aberrations in breast cancer2013

    • Author(s)
      Tokunaga E, Yamashita N, Tanaka K, Saeki H, Oki E, Kitao H, Morita M, Maehara Y
    • Organizer
      San Antonio Breast Cancer Symposium 2013
    • Place of Presentation
      サンアントニオ
    • Data Source
      KAKENHI-PROJECT-23591896
  • [Presentation] Subtype specific chromosomal aberrations in breast cancer2013

    • Author(s)
      Eriko Tokunaga, Nami Yamashita, Kenji Taketani, Koji Ando, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Masaru Morita, Yoshihiko Maehara
    • Organizer
      第72回 日本癌学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591896
  • [Presentation] 食道癌におけるLINE-1メチル化の検討2013

    • Author(s)
      河野 浩幸、北尾 洋之、日高  元、笠木 勇太、 津田 康雄、由茅 隆文、大津  甫、武谷 憲二、 安藤 幸滋、井田  智、木村 和恵、佐伯 浩司、 沖  英次、森田  勝、楠本 哲也、前原 喜彦
    • Organizer
      第67回日本食道学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] Rad9, Rad17, TopBP1 and Claspin Play Essential Roles in Heat-Induced Activation of ATR Kinase and Heat Tolerance.2013

    • Author(s)
      Tuul M., Kitao H., Matsuoka K., Iimori M., Kiyonari S., Yamamoto K., Morita M., Maehara Y.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] トリフルオロチミジンによるピリミジン代謝経路への影響とDNA損傷応答2013

    • Author(s)
      松岡 和明、飯森 真人、月原 宏志、清成 信一、渡邊すぎ子、徳永えり子、沖  英次、北尾 洋之、前原 喜彦
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] Subtype specific chromosomal aberrations in breast cancer2013

    • Author(s)
      Tokunaga E, Yamashita N, Taketani K, Ando K, Saeki H, Oki E, Kitao H, Morita M, Maehara Y
    • Organizer
      第72回日本癌学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591896
  • [Presentation] FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer.2012

    • Author(s)
      Nakanishi R., Kitao H., Fujinaka Y., Yamashita N., Iimori M., Tokunaga E., Yamashita N., Morita M., Kakeji Y., Maehara Y.
    • Organizer
      The 8th International Symposium on Cancer Research and Therapy
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Presentation] Significance of mortalin expression in gastric cancer with normal p532012

    • Author(s)
      Ando K, Oki E, Yan Z, Kitao H, Saeki H, Ohga T, Kakeji Y, Tujitani S, Kohnoe S, Maehara Y.
    • Organizer
      ASCO GI 2012
    • Place of Presentation
      サンフランシスコ
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Presentation] 大腸癌におけるKRAS, BRAF変異とマイクロサテライト不安定性2012

    • Author(s)
      中西良太、趙岩、北尾洋之、安藤幸滋、佐伯浩司、大賀丈史、沖英次、掛地吉弘、辻谷俊一、鴻江俊治、前原喜彦
    • Organizer
      第45回制癌剤適応研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-03-02
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Presentation] 胃癌におけるDNA ploidyと紡錘体形成チェックポイントタンパク質BUBR1の発現2012

    • Author(s)
      安藤 幸滋、掛地 吉弘、中西 良太、久松 雄一、北尾 洋之、佐伯 浩司、沖  英次、大賀 丈史、辻谷 俊一、鴻江 俊治、前原 喜彦
    • Organizer
      第21回日本癌転移学会学術集会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Presentation] 胃癌におけるDNA ploidyと紡錘体形成チェックポイントタンパク質BUBR1の発現2012

    • Author(s)
      安藤幸滋、掛地吉弘、中西良太、久松雄一、北尾洋之、佐伯浩司、沖英次、大賀丈史、辻谷俊一、鴻江俊治、前原喜彦
    • Organizer
      第21回日本癌転移学会学術集会総会
    • Place of Presentation
      広島市
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Presentation] ATR-Chk1 signaling pathway arid homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity.2012

    • Author(s)
      Kitao H
    • Organizer
      第71回日本癌学会総会
    • Place of Presentation
      ロイトン札幌(札幌)
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] 大腸癌におけるDNA修復因子FANCJ発現と5-FU感受性2012

    • Author(s)
      中西良太、北尾洋之、藤中良彦、安藤幸滋、佐伯浩司、大賀丈史、徳永えり子、沖英次、掛地吉弘、辻谷俊一、鴻江俊治、前原喜彦
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Presentation] Functional role of FancJ in the cellular response to 5-FU-induced DNA damage.2012

    • Author(s)
      Kitao H
    • Organizer
      第35回日本分子生物学会総会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] 大腸癌におけるDNA修復因子FANCJの発現と5-FU感受性2012

    • Author(s)
      中西 良太、北尾 洋之、秋吉清百合、安藤 幸滋、佐伯 浩司、大賀 丈史、徳永えり子、沖  英次、掛地 吉弘、辻谷 俊一、鴻江 俊治、前原 喜彦
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Presentation] Significance of mortalin expression in gastric cancer with normal p532012

    • Author(s)
      Ando K,. Oki E., Yan Z., Kitao H., Saeki H., Ohga T., Kakeji Y., Tujitani S., Kohnoe S., Maehara Y.
    • Organizer
      ASCO GI
    • Place of Presentation
      San Francisco
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Presentation] Hyperthermia activates both ATM and ATR signaling pathways for cell tolerance against heat.2012

    • Author(s)
      Kitao H
    • Organizer
      The 11^<th> International Congress of Hyperthermic Oncology, The 29^<th> Japanese Congress of Thermal Medicine Joint meeting 2012
    • Place of Presentation
      ハイアットリージェンシー京都
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation]2012

    • Author(s)
      Nakanishi R, Kitao H, Fujinaka Y, Yamashita N, Iimori M, Tokunaga E, Yamashita N, Morita M, Kakeji Y, Maehara Y.
    • Organizer
      The 8th International Symposium on Cancer Research and Therapy
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591964
  • [Presentation] Different impact of the loss of heterozygosity at BRCA1 and BRCA2 loci on clinicopathological features of breast cancer2011

    • Author(s)
      Tokunaga E, Okada S, Akiyoshi S, Yamashita N, Ando N, Saeki H, Oki E, Ohga T, Kitao H, Kakeji Y, Maehara Y
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23591896
  • [Presentation] 5-FUにより誘起されるDNA損傷に対する細胞応答機構2011

    • Author(s)
      北尾洋之、藤中良彦、飯森真人、ムンフボルド・トール、中西良太、山下奈真、松岡和明、掛地吉弘、前原喜彦
    • Organizer
      第15回日本がん分子標的治療学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] Involvement of FancJ and Msh2 in the cellular response to 5-FU-induced DNA damages2011

    • Author(s)
      Kitao, et al
    • Organizer
      23^<rd> Annual Fanconi Anemia Research Fund Scientific Symposium
    • Place of Presentation
      スペイン・バルセロナ
    • Year and Date
      2011-10-20
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells2011

    • Author(s)
      Kitao, et al
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] Homologous recombinational repair and Chk1-mediated S phase arrest protect cells from 5-FU cytotoxicity2011

    • Author(s)
      Kitao H, Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yamamoto K, Takata M, Kakeji Y, Maehara Y
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] 家族性乳がん遺伝子FancJ/Brip1ヘリカーゼ欠損によって起こる大規模ゲノム欠失・増幅2011

    • Author(s)
      北尾洋之、高田穣、前原喜彦
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] Chk1-mediated S phase arrest and homologous recombinational repair protect cells from 5-FU cytotoxicity2011

    • Author(s)
      Kitao, et al
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] Involvement of FancJ and Msh2 in the cellular response to 5-FU-induced DNA damages2011

    • Author(s)
      Kitao H, Nakanishi R, Iimori M, Fujinaka Y, Tuul M, Yamashita N, Takata M, Kakeji Y, Maehara Y
    • Organizer
      23rd Annual Fanconi Anemia Research Fund Scientific Symposium
    • Place of Presentation
      スペイン・バルセロナ
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] 5-FUにより発生するDNA損傷に対する細胞応答機構2011

    • Author(s)
      北尾洋之, 他
    • Organizer
      第17回日本がん分子標的治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-23
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] Possible contribution of FancJ in the repair process of 5-FU-induced DNA damages2010

    • Author(s)
      Kitao H, Nakanishi R, Iimori M, Fujinaka Y, Tuul M, Yamashita N, Takata M, Kakeji Y, Maehara Y
    • Organizer
      22^<nd> Annual Fanconi Anemia Research Fund Scientific Symposium
    • Place of Presentation
      米国ミネアポリス
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] 5-FUによるファンコニ貧血経路活性化のメカニズム2010

    • Author(s)
      北尾洋之、藤中良彦、飯森真人、ムンフボルド・トール、中西良太、山下奈真、久保信英、吉永敬士、徳永えり子、森田勝、掛地吉弘、前原喜彦
    • Organizer
      第14回日本がん分子標的治療学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] 5-FUによるファンコニ貧血経路活性化におけるChk1の役割2010

    • Author(s)
      北尾洋之、飯森真人、ムンフボルド・トール、藤中良彦、久保信英、中西良太、山下奈真、吉永敬士、徳永えり子、森田勝、掛地吉弘、前原喜彦
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] GENOME INSTABILITY PHENOTYPES INDUCED BY LOSS OF FANCJ/BRIP1 FUNCTION2010

    • Author(s)
      Kitao H, Nanda I, Kakeji Y, Maehara Y, Takata M
    • Organizer
      100^<th> Annual Meeting American Association for Cancer Research
    • Place of Presentation
      米国デンバー
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] A novel role of FancJ in the cellular response to 5-FU-induced DNA damages2010

    • Author(s)
      Kitao H, Nakanishi R, Iimori M, Fujinaka Y, Tuul M, Yamashita N, Takata M, Kakeji Y, Maehara Y
    • Organizer
      8^<th> Joint Conference of the AACR and JCA
    • Place of Presentation
      ハワイ
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] A novel role of FancJ in the cellular response to 5-FU-induced DNA damages2010

    • Author(s)
      Kitao H, Iimori M, Fujinaka Y, Kubo N, Nakanishi R, Munkhbold T, Yoshinaga K, Tokunaga E, Saeki H, Morita M, Kakeji Y, Takata M, Maehara Y.
    • Organizer
      8^<th> AACR/JCA Conference
    • Place of Presentation
      Hilton Waikoloa Village, Waikoloa, Hawaii, USA
    • Year and Date
      2010-02-09
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] Possible contribution of FancJ in the repair process of 5-FU-induced DNA damages2010

    • Author(s)
      Kitao H, Iimori M, Fujinaka Y, Nakanishi R, Tuul M, Yamashita N, Kubo N, Kakeji Y, Takata M, Maehara Y.
    • Organizer
      22^<nd> Fanconi Anemia Research Fund Annual Meeting
    • Place of Presentation
      Minneapolis, MN
    • Year and Date
      2010-10-21
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] 5-FU感受性規定因子としてのファンコニ貧血経路とその分子機序の解明2009

    • Author(s)
      北尾洋之、藤中良彦、飯森真人、ムンフボルド・トール、久保信英、吉永敬士、中西良太、掛地吉弘、福島正和、高田穣、前原喜彦
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] Genomic instability phenotypes induced by loss of FancJ/Brip1 function2009

    • Author(s)
      Kitao H, Nanda I, Kakeji Y, Maehara Y, Takata M
    • Organizer
      American Association for Cancer Research 100th Annual Meeting
    • Place of Presentation
      Colorado Convention Center, Denver,CO
    • Year and Date
      2009-04-19
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] A novel role of the FA core complex in FANCI phosphorylation, an important switch in the FA pathway.2009

    • Author(s)
      Minoru Takata, Junya Tomida, Tomoko Shigechi, Hiroyuki Kitao, Akiko Itaya, Masamichilshiai
    • Organizer
      Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium
    • Place of Presentation
      Baltimore, MA, USA
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Presentation] FancJ/Brip1ヘリカーゼ欠損により生じるゲノム不安定性症候群2008

    • Author(s)
      北尾洋之
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] Role of FANCI protein and its phosphorylation for the Fanconi anemia pathway function2008

    • Author(s)
      M. Takata, H. Kitao, A. kinomura, A. Smogorzewska, S. J. Elledge, M. Ishiai
    • Organizer
      Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Presentation] ファンコニ貧血経路の活性化制御とFANCIタンパク質のリン酸化メカニズム2008

    • Author(s)
      冨田純也、内田亜希子、北尾洋之、木下英司、内田恵美、小林昌彦、山本健一、小池透、石合正道、高田穣
    • Organizer
      日本放射線影響学会第51回大会
    • Place of Presentation
      北九州市
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Symposium : "DNA repair network deficiency and carcinogenesis"2008

    • Author(s)
      Ishiai M, Kitao H, Takata M.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋市, 神戸
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Presentation] Frequent Loss of the Immunogolobulin Heavy Chain Gene Occurs in FANCJ deficient DT40 Cell Line2008

    • Author(s)
      H. Kitao, I. Nada, A. Kinomura, M. Takata
    • Organizer
      Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium
    • Place of Presentation
      Chicago
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Presentation] FancJ/Brip1ヘリカーゼ欠損により生じるゲノム不安定性表現型2008

    • Author(s)
      北尾洋之、Indrajit Nanda、木野村愛子、山添光芳、Michael Schmid、武田俊一、吉永敬士、前原喜彦、高田穣
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] ユビキチン化とリン酸化によるファンコニ貧血経路の制御機構2008

    • Author(s)
      石合正道、北尾洋之、高田穣
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway Symposium.2008

    • Author(s)
      Ishiai M, Kitao H, Takata M
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Presentation] FANCI phosphorylation functions as a-molecular switch toturn on the Fanconi anemia pathway. Symposium2008

    • Author(s)
      Ishiai M, Kitao H, Takata M
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Presentation] Takata M. Frequent loss of the Immunoglobulin heavy chain gene occurs in FANCJ-deficient DT40 cell line2008

    • Author(s)
      Kitao H, Nanda I, Kinomura A, Schmid M, Takata M
    • Organizer
      Ataxia-Telangiectasia Workshop 2008
    • Place of Presentation
      大津プリンスホテル
    • Year and Date
      2008-04-25
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] ファンコニ貧血経路の制御とFANCI タンパク質のリン酸化メカニズム2008

    • Author(s)
      冨田純也、内田亜希子、北尾洋之、木下英司、内田恵美、小林昌彦、山本健一、小池透、石合正道、高田穣
    • Organizer
      第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Presentation] BRCmotif-RPA融合蛋白はBRCA2欠損細胞の相同組換え修復異常を相補する2008

    • Author(s)
      佐伯浩司、北尾洋之、江見泰徳、森田勝、掛地吉弘、前原喜彦、Maria Jasin
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Symposium "DNA repair network deficiency and carcinogenesis".2008

    • Author(s)
      Ishiai M., Kitao H., Takata M.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-17013083
  • [Presentation] ファンコニ貧血コア複合体によるモノユビキチン化とDNAクロスリンク修復制御2007

    • Author(s)
      高田穣、北尾洋之、木野村愛子、石合正道
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Presentation] FancJ/BRIP1 helicasedeficient cells display huge loss of rearranged IgH locus2007

    • Author(s)
      Kitao H, Kinomura A, Kimura M, Ishiai M, Takata M
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] Emergence of EGFR T790M mutation during chronic exposure to gefitinib in a non-small cell lung cancer cell line2007

    • Author(s)
      Ogino A, Kitao H, Uchida A, Ishiai M, Takigawa N, Takata M, Kiura K, Tanimoto M
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-10-05
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] Role of FANCI protein and its pathway function2007

    • Author(s)
      Takata M, Kitao H, Kinomura A, Smogorzewska A, Elledge SJ, Ishiai M
    • Organizer
      19th Annual Fanconi Anemia Research
    • Place of Presentation
      The Westin Michigan Avenue, Chicago, IL.
    • Year and Date
      2007-10-10
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] Regulation of DNA crosslink repair through monoubiquitination mediated by the Fanconi anemia core complex2007

    • Author(s)
      Takata M, Kitao H, Kinomura A, Ishiai M
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] Frequent loss of the Immunoglobulin Heavy Chain Gene Occurs in FANCJ-deficient DT40 cell line2007

    • Author(s)
      Kitao H, Nanda I, Kinomura A, Schmid M, Takata M
    • Organizer
      19th Annual Fanconi Anemia Research Fund Scientific Symposium
    • Place of Presentation
      The Westin Michigan Avenue, Chicago, IL.
    • Year and Date
      2007-10-10
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] ファンコニ貧血コア複合体によるFANCD2/FANCI複合体のモノユビキチン化と相同組換え修復。ワークショップ 放射線DNA損傷修復機構研究の最前線2007

    • Author(s)
      高田穣、北尾洋之、木野村愛子、石合正道
    • Organizer
      放射線影響学会6第50回大会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Presentation] Frequent loss of the immunoglobulin heavy chain geneoccurs in FANCJ-deficient DT40 cells2007

    • Author(s)
      Hiroyuki Kitao
    • Organizer
      19th Annual Fanconi Anemia Research Fund Scientific Symposium
    • Place of Presentation
      Chicago, MI
    • Year and Date
      2007-10-10
    • Data Source
      KAKENHI-PROJECT-19790234
  • [Presentation] FANCJ 遺伝子欠損DT40細胞株で起こる免疫グロブリン重鎖遺伝子でのゲノム欠失2007

    • Author(s)
      北尾洋之、ナンダインドラジット、木野村愛子、シュミットマイケル、高田穣
    • Organizer
      ワークショップ第30回分子生物学会第80回日本生化学会合同大会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-19390087
  • [Presentation] Coexistence of LOH at BRCA1 and TP53 loci is associated with aggressive phenotype and poor prognosis in breast cancer

    • Author(s)
      Eriko Tokunaga, Nami Yamashita, Kenji Taketani, Koji Ando, Yasue Kimura, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Masaru Morita, Yoshihiko Maehara
    • Organizer
      日本癌学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23591896
  • [Presentation] 5-FU感受性規定因子としてのファンコニ貧血経路

    • Author(s)
      北尾洋之、藤中良彦、久保信英、中ノ子智徳、茂地智子、吉永敬士、ムンフボルド・トール、佐伯浩司、徳永えり子、江見泰徳、森田勝、掛地吉弘、前原喜彦
    • Organizer
      第13回日本がん分子標的治療学会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-21590338
  • [Presentation] 消化器癌におけるDNA aneuploidyの意義

    • Author(s)
      安藤 幸滋、沖  英次、吉田 綾恵、北尾 洋之、飯森 真人、 佐伯 浩司、中島雄一郎、今村 裕、大垣 吉平、前原 喜彦
    • Organizer
      第25回日本消化器癌発生学会総会 第8回国際消化器癌発生会議
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-13 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] 食道癌におけるLINE-1メチル化の生物学的意義および染色体不安定性に対する検討

    • Author(s)
      河野 浩幸、北尾 洋之、大津  甫、安藤 幸滋、日吉 幸晴、 伊藤 修平、佐伯 浩司、沖 英次、森田 勝、前原 喜彦
    • Organizer
      第114回日本外科学会定期学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-04-03 – 2014-04-05
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] 食道癌におけるグローバルDNA低メチル化と染色体不安定性

    • Author(s)
      佐伯 浩司、河野 浩幸、西村 章、堤 亮介、中司 悠、 工藤 健介、堤 智崇、由茅 隆文、田尻 裕匡、笠木 勇太、 津田 康雄、財津 瑛子、安藤 幸滋、中島雄一郎、今村 裕、大垣 吉平、沖 英次、北尾 洋之、前原 喜彦
    • Organizer
      第25回日本消化器癌発生学会総会 第8回国際消化器癌発生会議
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-13 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] Cellular response to a fluorinated thymidine analogue trifluridine, a key component of the novel oral antitumor drug TAS-102.

    • Author(s)
      Hiroyuki Kitao
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Rockport, RI
    • Year and Date
      2015-06-28 – 2015-07-03
    • Data Source
      KAKENHI-PROJECT-25460390
  • [Presentation] Global DNA hypomethylation-mediated chromosomal instability is related to the initiation and progression of esophageal squamous cell carcinoma

    • Author(s)
      Kawano H., Saeki H., Kitao H., Tsuda Y., Otsu H., Ando K., Ito S., Egashira A., Oki E., Morita M., Maehara Y.
    • Organizer
      ASCO 2014 Annual meeting
    • Place of Presentation
      Chicago
    • Year and Date
      2014-05-30 – 2014-06-03
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] Global DNA hypomethylation-mediated chromosomal instability is related to the initiation and progression of esophageal squamous cell carcinoma

    • Author(s)
      Kawano H, Saeki H, Kitao H, Tsuda Y, Otsu H, Ando K, Ito S, Egashira A, Oki E, Morita M, Maehara Y
    • Organizer
      2014 Annual meeting of American Society of Clinical Oncology (ASCO)
    • Place of Presentation
      Chicago
    • Year and Date
      2014-05-30 – 2014-06-03
    • Data Source
      KAKENHI-PROJECT-25462024
  • [Presentation] Trifluridine induces p53-dependent sustained G2 phase arrest with its massive misincorporation into DNA and few DNA strand breaks

    • Author(s)
      Matsuoka K, Kitao H, 他
    • Organizer
      American Association of Cancer Research (AACR) Annual Meeting 2015
    • Place of Presentation
      Philadelphia, PA
    • Year and Date
      2015-04-18 – 2015-04-22
    • Data Source
      KAKENHI-PROJECT-24390321
  • [Presentation] 食道癌におけるグローバルDNA低メチル化と染色体不安定性

    • Author(s)
      佐伯浩司、河野浩幸、西村 章、堤 亮介、中司 悠、工藤健介、堤 智崇、由茅隆文、田尻裕匡、笠木勇太、津田康雄、財津瑛子、安藤幸滋、中島雄一郎、今村 裕、大垣吉平、沖 英次、北尾洋之、前原喜彦
    • Organizer
      第25回日本消化器癌発生学会総会/第8回国際消化器癌発生会議, シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-13 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-25462024
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