KITAO HIROYUKI 北尾洋之

… Alternative Names

KITAO Hiroyuki 北尾洋之

Less

Researcher Number	30368617
Other IDs
External Links
Affiliation (Current)	2025: 福岡歯科大学, 口腔歯学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 福岡歯科大学, 口腔歯学部, 教授 2017 – 2022: 九州大学, 薬学研究院, 教授 2015 – 2016: 九州大学, 医学研究院, 准教授 2015: 九州大学, 大学院医学研究科, 准教授 2011 – 2015: 九州大学, 医学(系)研究科(研究院), 准教授 … More 2011 – 2013: 九州大学, 医学研究院, 准教授 2008 – 2010: Kyushu University, 医学研究院, 客員准教授 2009: 京都大学, 放射線生物研究センター, 研究員 2008: Kyushu University, 医学研究院, 寄附講座教員 2007: Kyoto University, 放射線生物研究センター, 助教 2007: 京都大学, 放射線生物研究センター, 研究員 2006: Research Institute for Radiation Biology and Medicine, Postdoctoral Researcher for COE program, 原爆放射線医科学研究所, COE研究員 2004 – 2005: Kawasaki Med Sch, Deptcf Immunol and Mol Genet, Research Associate, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Medium-sized Section 50:Oncology and related fields / Tumor therapeutics Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / General surgery / Pathological medical chemistry / Biological Sciences / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Tumor biology / General medical chemistry
Keywords	Principal Investigator 複製ストレス / 抗がん剤 / ゲノム不安定性 / FANCJ / ファンコニ貧血 / 治療誘導性細胞老化 / DNA複製ストレス / BRCA1 / 家族性乳がん / 染色体不安定性 … More / 一本鎖DNA / 1本鎖DNA / ssDNA / ATR / 抗腫瘍効果 / RNA転写複合体 / FancD2 / RNA転写中間体 / M期スキップ / 細胞老化 / がん化学療法 / 抗癌剤 / ロンサーフ（TFTD,TAS-102） / トリフルリジン / FdUrd / MLH1 / 分子腫瘍学 / BRCAI / 家族性乳癌 / 遺伝性疾患 / 相同組換え修復 / DNA2重鎖切断 / DNA鎖間クロスリンク / 遺伝子破壊 / ニワトリB細胞株DT40 / 家族性乳ガン … More Except Principal Investigator DNA修復 / 染色体不安定性 / 大腸癌 / I-SceI / DNA repair / 集学的治療 / ゲノム不安定性 / ファンコニ貧血 / トランスレーショナルリサーチ / 細胞・組織 / estrogen receptor / DNA double strand break / TAT配列 / エストロジェン受容体 / homologous recombination / 姉妹染色分体交換 / 遺伝子変異 / MSI / 食道癌 / BUBR1 / 乳癌 / 相同DNA組み換え / DT40細胞 / モノユビキチン化 / ユビキチン化 / 細胞周期 / DNA複製ストレス / 化学療法 / 癌の浸潤・転移 / p53機能獲得型変異 / ｐ53機能獲得型変異 / 癌幹細胞化 / エピゲノム異常 / 遺伝子発現プロファイル / p53変異細胞株パネル / 機能獲得型p53変異 / 術後化学療法 / 周術期治療 / NGS解析 / LGR5 / 補助化学療法 / cDNAマクロアレイ / 術後補助療法 / ctDNA / 遺伝子サブタイプ / 遺伝子検査 / ゲノム検査 / ミッドボディ / 酸化ストレス / OGG1 / 細胞質分裂 / heterogeneity / 四倍体細胞 / 癌集学的治療 / 抗腫瘍免疫 / 免疫チェックポイント阻害剤 / マイクロサテライト不安定性 / 消化管外科 / 免疫チェックポイント阻害剤 / 食道扁平上皮癌 / 創薬 / プロテオーム / Sphere / 化合物ライブラリー / 造血幹細胞 / がん幹細胞 / Type IVcollagen / plasma fibronectin / 腹膜播種 / sphere / シグナル伝達 / 薬剤反応性 / 外科 / 癌 / tamoxifen / non-homologous end joining / DNA二重鎖切断修復 / DNA連鎖切断修復 / protein transduction / I-Sce I / プロテイントランスダクション / TAT配 / I-Scel / DNA二重鎖切断 / sister chromatid exchanges / Fanconi anemia / Rad51 paralogs / DT 40 cells / XRCC3 / Rad52 / Rad51ファミリー / Rad51 / 相同組み換え / 複製後修復 / ジーンターゲティング / 相同組替え / BLMヘリケース / Rad51パラログ / 化学放射線療法 / HLA ClassⅠ / PD-L1 / 腫瘍免疫 / PARP阻害剤 / DNA2重鎖修復 / サブタイプ / 癌抑制遺伝子 / ER陽性乳癌 / APOBEC3B / p53 / 細胞分裂期スピンドルチェックポイント機構 / 炎症 / LINE1 / メチル化 / BRAF / 低侵襲手術 / プロスタグランジン / 炎症性メデイエーター / DNAメチル化 / 遺伝子プロファイル / PAK / 難治性消化管癌 / 染色体分配機構 / 消化管癌 / DNA修復系関連遺伝子 / 5-FU感受性 / 胃十二指腸外科学 / 発がん / PLK1 / Aurora-B / Aurora-A / DNA aneuploidy / スピンドルチェックポイント / GATA-3 / FOXA1 / ホルモン感受性 / ホルモン抵抗性 / ホルモン療法 / ホルモン受容体 / チェックポイント / リン酸化 / チェックポイントキナーゼ / FAコア複合体 / ゲノム安定性 / シスプラチン / FANCI / FANCD2 Less

Antitumor strategy to synergize DNA replication stress-inducing anticancer drugs by controlling G2 phase of the cell cycle
- Principal Investigator
  
  野中謙太朗
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers
Establishment of therapeutic strategies based on the understanding of cancer stemness regulated by gain-of-function mutant p53
- Principal Investigator
  
  maehara yoshihiko
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers
The critical role of ATR activation in the process of therapy-induced senescencePrincipal Investigator
- Principal Investigator
  
  北尾洋之
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Fukuoka Dental College
Establishment of new selection system for adjuvant chemotherapy of colorectal cancer
- Principal Investigator
  
  OKI Eiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyushu University
RNA involvement in the process of chemotherapy-induced DNA replication stressPrincipal Investigator
- Principal Investigator
  
  Kitao Hiroyuki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kyushu University
Molecular mechanisms of cytokinesis completion and cell fate decision after cytokinesis failure
- Principal Investigator
  
  Iimori Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kyushu University
Molecular mechanism of therapy-induced senescence caused by replicative stressPrincipal Investigator
- Principal Investigator
  
  Kitao Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kyushu University
Elucidation of molecular mechanisms of and development of combined therapy with immune checkpoint inhibitors for digestive tract cancer
- Principal Investigator
  
  SAEKI hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Development of Innovative Treatment Targeting the Sphere Formation Mechanism Involving Cancer Stem Cells
- Principal Investigator
  
  Maehara Yoshihiko
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukuoka Dental College
  Kyushu University
Gemonic alteration, molecular subtypes and drug sensitivity in breast cancer
- Principal Investigator
  
  Tokunaga Eriko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Hospital Organization, Kyushu Cancer Center
  Kyushu University
Investigation of chemoradiation sensitivity based on the DNA repair mechanism in esophageal carcinoma
- Principal Investigator
  
  Ito Shuhei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Novel molecular targeting strategy against chromosomal maintenance factor FANCJPrincipal Investigator
- Principal Investigator
  
  KITAO HIROYUKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
Chromosomal dynamics and development of novel therapy in gastrointestinal tract cancer
- Principal Investigator
  
  Saeki Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Establishment of the new therapy based on inflammatory mediator and DNA methylation in colorectal cancer
- Principal Investigator
  
  Oki Eiji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
The analysis of the spindle checkpoint protens and the application to the new molecular targetted therapy for colorectal cancer.
- Principal Investigator
  
  Emi Yasunori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
DNA mismatch repair gene analysis predicts the response to anticancer drug sensitivity in gastrointestinal cancers for tailored therapy.
- Principal Investigator
  
  Kakeji Yoshihiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Molecular mechanisms of hormone sensitivity of hormone receptor-positive breast cancer and their application for individual treatment
- Principal Investigator
  
  TOKUNAGA Eriko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
A systematic study of the disorders in the spindle assembly checkpoint genes in colorectal cancer and its application to molecular targeted therapy
- Principal Investigator
  
  KOHNOE Shunji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Genomic instability in the absence of FANCJ and its possible contribution to tumorigenesisPrincipal Investigator
- Principal Investigator
  
  KITAO Hiroyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
Regulation of the ubiquitin system by checkpoint kinases in response to stalled replication forks
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Molecular mechanism of large genome deletion induced byDisrupting BRCA1-related gene, FA-J.Principal Investigator
- Principal Investigator
  
  KITAO Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
  Kyoto University
Functional analysis of Fanconi anemia genes that are involved in chromosomal stability and tumor prevention
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
  Hiroshima University
  Kawasaki Medical School
ファンコニ貧血遺伝子FA-D2と家族性乳ガン遺伝子Brca2との相互作用の再検討Principal Investigator
- Principal Investigator
  
  北尾洋之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hiroshima University
  Kawasaki Medical School
Induction of single DNA double strand break in animal cell genome and its monitoring methodology
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  HIROSHIMA UNIVERSITY
  Kawasaki Medical School
Physical monitoring of repair process of chromosomal double stand break induced by simultaneous nuclear introduction of I-SceI endonuclease
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kawasaki Medical School
Functional analysis of genes involved in maintenance of chromosome stability and homologous recombination
- Principal Investigator
  
  TAKATA Minoru
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kawasaki Medical School

[Book] トリフルリジン・チピラシル塩酸塩（TAS-102: TFTD）の抗腫瘍効果における分子機序2016
- Author(s)
  北尾洋之、松岡和明、飯森真人、徳永えり子、佐伯浩司、沖英次、宮本裕士、馬場秀夫、前原喜彦
- Total Pages
  7
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-24390321
[Book] 別冊日本臨床新領域別症候群シリーズ「先天代謝異常症候群第2版(上)」-病因・病態研究、診断・治療の進歩-ファンコニ貧血2012
- Author(s)
  北尾洋之
- Total Pages
  688
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-24390321
[Journal Article] The anti-tumor effect of trifluridine via induction of aberrant mitosis is unaffected by mutations modulating p53 activity2023
- Author(s)
  Wakasa Takeshi、Iimori Makoto、Nonaka Kentaro、Oki Eiji、Maehara Yoshihiko、Kitao Hiroyuki et al.
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2023.08.30.555463
- Data Source
  KAKENHI-PROJECT-22K19577
[Journal Article] Mutational spectrum of TP53 gene correlates with nivolumab treatment efficacy in advanced gastric cancer (TP53MUT study)2023
- Author(s)
  Ando Koji、Nakamura Yoshiaki、Narita Yukiya、Hara Hiroki、Ohta Takashi、Esaki Taito、Hamamoto Yasuo、Kato Ken、Yamamoto Yoshiyuki、Minashi Keiko、Ohtsubo Koushiro、Izawa Naoki、Kawakami Hisato、Kato Takeshi、Satoh Taroh、Okano Naohiro、Tsuji Akihito、Yamazaki Kentaro、Yoshino Takayuki、Maehara Yoshihiko、Oki Eiji
- Journal Title
  
  British Journal of Cancer
  
  Volume: 129 Issue: 6 Pages: 1032-1039
- DOI
  10.1038/s41416-023-02378-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19559, KAKENHI-PROJECT-22K19577, KAKENHI-PROJECT-23K24405
[Journal Article] Lineage of drug discovery research on fluorinated pyrimidines: chronicle of the achievements accomplished by Professor Setsuro Fujii2023
- Author(s)
  Maehara Yoshihiko、Oki Eiji、Kitao Hiroyuki、Iimori Makoto、Makino Kunio、Takechi Teiji、Sagara Takeshi、Miyadera Kazutaka、Matsuoka Kazuaki、Wakasa Takeshi、Ochiiwa Hiroaki、et al.
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 28 Issue: 5 Pages: 613-624
- DOI
  10.1007/s10147-023-02326-w
- Data Source
  KAKENHI-PROJECT-22K19577
[Journal Article] CD44v3,8‐10 is essential for Slug‐dependent <i>vimentin</i> gene expression to acquire TGF‐β1‐induced tumor cell motility2022
- Author(s)
  Qiu Shichao、Iimori Makoto、Edahiro Keitaro、Fujimoto Yoshiaki、Matsuoka Kazuaki、Oki Eiji、Maehara Yoshihiko、Mori Masaki、Kitao Hiroyuki
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 8 Pages: 2654-2667
- DOI
  10.1111/cas.15353
- Data Source
  KAKENHI-PROJECT-22K19577
[Journal Article] Lack of impact of the <scp>ALDH2</scp> rs671 variant on breast cancer development in Japanese <scp>BRCA1</scp> /2‐mutation carriers2022
- Author(s)
  Mori Tomoharu、Takata Minoru et al.
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 6 Pages: 6594-6602
- DOI
  10.1002/cam4.5430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21394, KAKENHI-PROJECT-22K19577, KAKENHI-PROJECT-21K15362, KAKENHI-PROJECT-20H03450, KAKENHI-PROJECT-20H03748
[Journal Article] Detection of trifluridine in tumors of patients with metastatic colorectal cancer treated with trifluridine/tipiracil. Cancer.2020
- Author(s)
  Fujimoto Y, Nakanishi R, Nukatsuka M, Matsuoka K, Ando K, Wakasa T, Kitao H, Oki E, Maehara Y, Mori M.
- Journal Title
  
  Chemother Pharmacol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05792
[Journal Article] DNA replication stress induced by trifluridine determines tumor cell fate according to p53 status2020
- Author(s)
  Kataoka Yuki、Iimori Makoto、Fujisawa Ryo、Morikawa-Ichinose Tomomi、Niimi Shinichiro、Wakasa Takeshi、Saeki Hiroshi、Oki Eiji、Miura Daisuke、Tsurimoto Toshiki、Maehara Yoshihiko、Kitao Hiroyuki
- Journal Title
  
  Molecular Cancer Research
  
  Volume: - Issue: 9 Pages: 1354-1366
- DOI
  10.1158/1541-7786.mcr-19-1051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-18K19478
[Journal Article] Detection of trifluridine in tumors of patients with metastatic colorectal cancer treated with trifluridine/tipiracil.2020
- Author(s)
  Fujimoto Yoshiaki, Nakanishi Ryota, Nukatsuka Mamoru, Matsuoka Kazuaki, Ando Koji, Wakasa Takeshi, Kitao Hiroyuki, Oki Eiji, Maehara Yoshihiko, Mori Masaki
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: - Issue: 6 Pages: 1029-1038
- DOI
  10.1007/s00280-020-04072-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-18K15282
[Journal Article] Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level2019
- Author(s)
  Kataoka Yuki、Iimori Makoto、Niimi Shinichiro、Tsukihara Hiroshi、Wakasa Takeshi、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko、Kitao Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 7964-7964
- DOI
  10.1038/s41598-019-44399-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05792, KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-18K19478
[Journal Article] A minimal threshold of FANCJ helicase activity is required for its response to replication stress or double-strand break repair2018
- Author(s)
  Bharti Sanjay Kumar、Sommers Joshua A、Awate Sanket、Bellani Marina A、Khan Irfan、Bradley Lynda、King Graeme A、Seol Yeonee、Vidhyasagar Venkatasubramanian、Wu Yuliang、Abe Takuye、Kobayashi Koji、Shin-ya Kazuo、Kitao Hiroyuki、Wold Marc S、Branzei Dana、Neuman Keir C、Brosh Robert M
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 46 Issue: 12 Pages: 6238-6256
- DOI
  10.1093/nar/gky403
- Data Source
  KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-17H03598
[Journal Article] MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites2018
- Author(s)
  Watanabe Sugiko、Iimori Makoto、Chan David Virya、Hara Eiji、Kitao Hiroyuki、Maehara Yoshihiko
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10888-10888
- DOI
  10.1038/s41598-018-29239-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-15H05792
[Journal Article] Epithelial Paradox: Clinical Significance of Coexpression of E-cadherin and Vimentin With?Regard to Invasion and Metastasis of Breast?Cancer2018
- Author(s)
  Yamashita Nami、Tokunaga Eriko、Iimori Makoto、Inoue Yuka、Tanaka Kimihiro、Kitao Hiroyuki、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko
- Journal Title
  
  Clinical Breast Cancer
  
  Volume: 印刷中 Issue: 5 Pages: e1003-e1009
- DOI
  10.1016/j.clbc.2018.02.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19899, KAKENHI-PROJECT-18K08576, KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-15H05792
[Journal Article] Thymidine Kinase 1 Loss Confers Trifluridine Resistance without Affecting 5-Fluorouracil Metabolism and Cytotoxicity2018
- Author(s)
  Edahiro Keitaro、Iimori Makoto、Kobunai Takashi、Morikawa-Ichinose Tomomi、Miura Daisuke、Kataoka Yuki、Niimi Shinichiro、Wakasa Takeshi、Saeki Hiroshi、Oki Eiji、Kitao Hiroyuki、Maehara Yoshihiko
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 16 Issue: 10 Pages: 1483-1490
- DOI
  10.1158/1541-7786.mcr-17-0686
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19478, KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-16J40073, KAKENHI-PROJECT-16K10502, KAKENHI-PROJECT-15H05792
[Journal Article] DNA replication stress and cancer chemotherapy2018
- Author(s)
  Kitao Hiroyuki、Iimori Makoto、Kataoka Yuki、Wakasa Takeshi、Tokunaga Eriko、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 2 Pages: 264-271
- DOI
  10.1111/cas.13455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03598
[Journal Article] Activation of the FA pathway mediated by phosphorylation and ubiquitination2017
- Author(s)
  Ishiai M., Sato K, Tomida J, Kitao H., Kurumizaka H., Takata M.
- Journal Title
  
  Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
  
  Volume: 803-805 Pages: 89-95
- DOI
  10.1016/j.mrfmmm.2017.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-17H03598
[Journal Article] Clinical Significance of the Wild Type p53-Induced Phosphatase 1 Expression in Invasive Breast Cancer2017
- Author(s)
  Inoue Yuka、Yamashita Nami、Kitao Hiroyuki、Tanaka Kimihiro、Saeki Hiroshi、Oki Eiji、Oda Yoshinao、Tokunaga Eriko、Maehara Yoshihiko
- Journal Title
  
  Clinical Breast Cancer
  
  Volume: 印刷中 Issue: 4 Pages: e643-e650
- DOI
  10.1016/j.clbc.2017.11.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03598, KAKENHI-PROJECT-16K19899, KAKENHI-PROJECT-18K08576, KAKENHI-PROJECT-15H05792
[Journal Article] Mitotic slippage and the subsequent cell fates after inhibition of Aurora B during tubulin-binding agent?induced mitotic arrest2017
- Author(s)
  Tsuda Yasuo、Iimori Makoto、Nakashima Yuichiro、Nakanishi Ryota、Ando Koji、Ohgaki Kippei、Kitao Hiroyuki、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 16762-16762
- DOI
  10.1038/s41598-017-17002-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03598
[Journal Article] Monitoring trifluridine incorporation in the peripheral blood mononuclear cells of colorectal cancer patients under trifluridine/tipiracil medication2017
- Author(s)
  Nakanishi Ryota、Kitao Hiroyuki、Kiniwa Mamoru、Morodomi Yosuke、Iimori Makoto、Kurashige Junji、Sugiyama Masahiko、Nakashima Yuichiro、Saeki Hiroshi、Oki Eiji、Maehara Yoshihiko
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 16969-16969
- DOI
  10.1038/s41598-017-17282-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16564, KAKENHI-PROJECT-17H03598
[Journal Article] Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.2016
- Author(s)
  Tokunaga E, Yamashita N, Tanaka K, Inoue Y, Akiyoshi S, Saeki H, Oki E, Kitao H, Maehara Y.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 12 Pages: e0168090-e0168090
- DOI
  10.1371/journal.pone.0168090
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] Gastric cancer patients with high PLK1 expression and DNA aneuploidy correlate with poor prognosis.2016
- Author(s)
  Otsu H,Iimori M, Ando K,Saeki H, Aishima S,Oda Y,Morita M, Matsuo K,Kitao H,Oki E, Maehara Y.
- Journal Title
  
  Oncology
  
  Volume: - Issue: 1 Pages: 31-40
- DOI
  10.1159/000445952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-15K10125
[Journal Article] Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.2016
- Author(s)
  Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, Oki E, Kitao H, Maehara Y:
- Journal Title
  
  Nature Communications
  
  Volume: [Epub ahead of print] Issue: 1 Pages: 11117-11117
- DOI
  10.1038/ncomms11117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462024, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-15H05792, KAKENHI-PROJECT-26281025, KAKENHI-PROJECT-26430116
[Journal Article] Biological and clinical significance of loss of heterozygosity at the INPP4B gene locus in Japanese breast cancer.2016
- Author(s)
  Tokunaga E, Yamashita N, Kitao H, Tanaka K, Taketani K, Inoue Y, Saeki H, Oki E, Oda Y, Maehara Y.
- Journal Title
  
  The Breast
  
  Volume: 26 Pages: 62-68
- DOI
  10.1016/j.breast.2015.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] The impact of the expression of vimentin and Axl in breast cancer.2016
- Author(s)
  Tanaka K, Tokunaga E, Inoue Y, Yamashita N, Saeki H, Okano S, Kitao H, P Oki E, Oda Y, Maehara Y.
- Journal Title
  
  Clin Breast Cancer
  
  Volume: 16 Issue: 6 Pages: 520-526
- DOI
  10.1016/j.clbc.2016.06.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] Trifluridine Induces p53-Dependent Sustained G2 Phase Arrest with Its Massive Misincorporation into DNA and Few DNA Strand Breaks2015
- Author(s)
  Matsuoka K, Iimori M, Niimi S, Tsukihara H, Watanabe S, Kiyonari S, Kiniwa M, Ando K, Tokunaga E, Saeki H, Oki E, Maehara Y, Kitao H.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 14 Issue: 4 Pages: 1004-1013
- DOI
  10.1158/1535-7163.mct-14-0236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-25460390
[Journal Article] The 1,2-diaminocyclohexane carrier ligand in oxaliplatin induces p53-dependent transcriptional repression of factors involved in thymidylate biosynthesis.2015
- Author(s)
  Kiyonari S, Iimori M, Matsuoka K, Watanabe S, Morikawa-Ichinose T, Miura D, Niimi S, Saeki H, Tokunaga E, Oki E, Morita M, Kadomatsu K, Maehara Y, Kitao H
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 14 Issue: 10 Pages: 2332-42
- DOI
  10.1158/1535-7163.mct-14-0748
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10125, KAKENHI-PROJECT-25460390, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-26713020
[Journal Article] Epigenetic Inactivation of BRCA1 Through Promoter Hypermethylation and Its Clinical Importance in Triple-Negative Breast Cancer.2015
- Author(s)
  Yamashita N, Tokunaga E, Kitao H, Hitchins M, Inoue Y, Tanaka K, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Oda Y, Saeki H, Oki E, Maehara Y.
- Journal Title
  
  Clin Breast Cancer
  
  Volume: 15 Issue: 6 Pages: 498-504
- DOI
  10.1016/j.clbc.2015.06.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461949
[Journal Article] Discrimination of p53 immunohistochemistry-positive tumors by its staining pattern in gastric cancer.2015
- Author(s)
  Ando K, Oki E, Saeki H, Yan Z, Tsuda Y, Hidaka G, Kasagi Y, Otsu H, Kawano H, Kitao H, Morita M, Maehara Y.
- Journal Title
  
  Cancer Med.
  
  Volume: 4 Issue: 1 Pages: 75-83
- DOI
  10.1002/cam4.346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-15K10125, KAKENHI-PROJECT-15K10127
[Journal Article] Mortalin is a prognostic factor of gastric cancer with normal p53 function2014
- Author(s)
  Ando K, Oki E, Zhao Y, Yoshida A, Kitao H, Saeki H, Kimura Y, Ida S, Morita M, Kusumoto T, Maehara Y.
- Journal Title
  
  Gastric Cancer
  
  Volume: 17(2) Pages: 255-262
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] Oxidative DNA damage in human esophageal cancer: clinicopathological analysis of 8-hydroxydeoxyguanosine and its repair enzyme.2014
- Author(s)
  Kubo N, Morita M, Nakashima Y, Kitao H, Egashira A, Saeki H, Oki E, Kakeji Y, Oda Y, Maehara Y.
- Journal Title
  
  Dis Esophagus.
  
  Volume: 27 Issue: 3 Pages: 285-293
- DOI
  10.1111/dote.12107
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-25460390
[Journal Article] Aberrations of BUBR1 and TP53 gene mutually associated with chromosomal instability in human colorectal cancer.2014
- Author(s)
  Zhao Y, Ando K, Oki E, Ikawa-Yoshida A, Ida S, Kimura Y, Saeki H, Kitao H, Morita M, Maehara Y.
- Journal Title
  
  Anticancer Res.
  
  Volume: 34 Pages: 5313-5320
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390321
[Journal Article] Mortalin is a prognostic factor of gastric cancer with normal p53 function.2014
- Author(s)
  Ando K., Oki E., Zhao Y., Yoshida A., Kitao H., Saeki H., Kimura Y., Ida S., Morita M., Kusumoto T., Maehara Y.
- Journal Title
  
  Gastric Cancer
  
  Volume: 17(2) Issue: 2 Pages: 255-262
- DOI
  10.1007/s10120-013-0279-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-24659614
[Journal Article] Chromosomal instability associated with global DNA hypomethylation is associated with the initiation and progression of esophageal squamous cell carcinoma2014
- Author(s)
  Kawano H, Saeki H, Kitao H, Tsuda Y, Otsu H, Ando K, Ito S, Egashira A, Oki E, Morita M, Oda Y, Maehara Y.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 4 Issue: S4 Pages: 696-702
- DOI
  10.1245/s10434-014-3818-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-25460390, KAKENHI-PROJECT-25462024
[Journal Article] Molecular mechanisms regulating the hormone sensitivity of breast cancer.2014
- Author(s)
  Tokunaga E1, Hisamatsu Y, Tanaka K, Yamashita N, Saeki H, Oki E, Kitao H, Maehara Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105(11) Issue: 11 Pages: 1377-1377
- DOI
  10.1111/cas.12521
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25861160, KAKENHI-PROJECT-26461949
[Journal Article] Contribution of Auroa-A and -B expression to DNA aneuploidy in gastric cancers.2014
- Author(s)
  Honma K., Nakanishi R., Nakanoko T., Ando K., Saeki H., Oki E., Iimori M., Kitao H., Kakeji Y., Maehara Y.
- Journal Title
  
  Surgery Today
  
  Volume: 44(3) Issue: 3 Pages: 454-461
- DOI
  10.1007/s00595-013-0581-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24390321
[Journal Article] Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer2014
- Author(s)
  Tokunaga E, Nakashima Y, Yamashita N, Hisamatsu Y, Okada S, Akiyoshi S, Aishima S, Kitao H, Morita M, Maehara Y
- Journal Title
  
  Breast Cancer
  
  Volume: 21 Pages: 341-9
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer.2014
- Author(s)
  Tokunaga E, Nakashima Y, Yamashita N, Hisamatsu Y, Okada S, Akiyoshi S, Aishima S, Kitao H, Morita M, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume: 21 Issue: 3 Pages: 341-349
- DOI
  10.1007/s12282-012-0398-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896, KAKENHI-PROJECT-25861160
[Journal Article] Contribution of Aurora-A and–B expression to DNA aneuploidy in gastric cancer2014
- Author(s)
  Honma K, Nakanishi R, Nakanoko T, Ando K, Saeki H, Oki E, Iimori M, Kitao H, Kakeji Y, Maehara Y.
- Journal Title
  
  Surg Today
  
  Volume: 44(3) Pages: 454-461
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer2013
- Author(s)
  Nakanishi R, Harada J, Tuul M, Zhao Y, Ando K, Saeki H, Oki E, Ohga T, Kitao H, Kakeji Y, Maehara Y.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 18(6) Pages: 1042-1048
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] Contribution of BubR1 to oxidative stress-induced aneuploidy in p53-deficient cells.2013
- Author(s)
  Ikawa-Yoshida A., Ando K., Oki E., Saeki H., Kumashiro R., Taketani K., Ida S., Tokunaga E., Kitao H., Morita M., Maehara Y.
- Journal Title
  
  Cancer Medicine
  
  Volume: 2(4) Issue: 4 Pages: 447-456
- DOI
  10.1002/cam4.101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-24659614, KAKENHI-PROJECT-25462058
[Journal Article] Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer.2013
- Author(s)
  Nakanishi R, Harada J, Tuul M, Zhao Y, Ando K, Saeki H, Oki E, Ohga T, Kitao H, Kakeji Y, Maehara Y
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 18(6) Issue: 6 Pages: 1042-1048
- DOI
  10.1007/s10147-012-0501-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390321
[Journal Article] Mortalin is a prognostic factor of gastric cancer with normal p53 function.2013
- Author(s)
  Ando K., Oki E., Zhao Y., Yoshida A., Kitao H., Saeki H., Kimura Y., Ida S., Morita M., Kusumoto T., Maehara Y.
- Journal Title
  
  Gastric Cancer
  
  Volume: 17 Pages: 255-262
- NAID
  40020216055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462059
[Journal Article] Vimentin as a poor prognostic factor for triple-negative breast cancer2013
- Author(s)
  Yamashita N, Tokunaga E, Kitao H, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Aishima S, Morita M, Maehara Y
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 139 Pages: 739-46
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Congribution of BubR1 to oxidative stress-induced aneuploidy in p53- deficient cells2013
- Author(s)
  Ikawa-Yoshida A, Ando K, Oki E, Saeki H, Kumashiro R, Taketani K, Ida S, Tokunaga E, Kitao H, Morita M, Maehara Y.
- Journal Title
  
  Cancer Medicine
  
  Volume: 2(4) Pages: 447-456
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] Involvement of ribonucleotide reductase-M1 in 5-fluorouracil induced DNA damage in esophageal cancer cell lines.2013
- Author(s)
  Aoki Y, Sakogawa K, Hihara J, Emi M, Hamai Y, Kono K, Shi L, Sun J, Kitao H, Ikura T, Niida H, Nakanishi M, Okada M, Tashiro S.
- Journal Title
  
  Int J Oncol.
  
  Volume: 42(6) Issue: 6 Pages: 1951-60
- DOI
  10.3892/ijo.2013.1899
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22118003, KAKENHI-PLANNED-22131004, KAKENHI-PROJECT-23240124, KAKENHI-PROJECT-23501259, KAKENHI-PROJECT-23510061, KAKENHI-PROJECT-24390072, KAKENHI-PROJECT-24591944, KAKENHI-PROJECT-24659137, KAKENHI-PROJECT-25460390, KAKENHI-PROJECT-25462022, KAKENHI-PROJECT-25640066
[Journal Article] Vimentin as a poor prognostic factor for triple-negative breast cancer.2013
- Author(s)
  Yamashita N, Tokunaga E, Kitao H, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Aishima S, Morita M, Maehara Y.
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume: 139 Issue: 5 Pages: 739-746
- DOI
  10.1007/s00432-013-1376-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896, KAKENHI-PROJECT-25861160
[Journal Article] Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance2013
- Author(s)
  Tuul M
- Journal Title
  
  PLoS One
  
  Volume: 8巻(2号) Issue: 2 Pages: 55361-55361
- DOI
  10.1371/journal.pone.0055361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24701028, KAKENHI-PROJECT-25460390
[Journal Article] The Q Motif of Fanconi Anemia Group J Protein (FANCJ) DNA Helicase Regulates Its Dimerization, DNA Binding, and DNA Repair Function.2012
- Author(s)
  Wu Y., Sommers JA., Loiland JA., Kitao H., Kuper J., Kisker C., Brosh RM Jr.
- Journal Title
  
  J Biol Chem
  
  Volume: 287(26) Issue: 26 Pages: 21699-716
- DOI
  10.1074/jbc.m112.351338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer.2012
- Author(s)
  Nakanishi R., Harada J., Tuul M., Zhao Y., Ando K., Saeki H., Oki E., Ohga T., Kitao H., Kakeji Y.,
- Journal Title
  
  Int J Clin Oncol
  
  Volume: Nov 29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple negative breast cancers2012
- Author(s)
  Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Breast Cancer
  
  Volume: 19 Pages: 161-9
- NAID
  10030981059
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] 胃癌における紡錘体形成チェックポイントタンパク質の発現異常とDNA aneuploidy2012
- Author(s)
  安藤　幸滋、北尾　洋之、飯森　真人、沖　　英次、佐伯　浩司、大賀　丈史、掛地　吉弘、辻谷　俊一、鴻江　俊治、前原　喜彦
- Journal Title
  
  胃がんperspective
  
  Volume: 5(1) Pages: 224-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] PARP and CSB modulate the processing of transcription-mediated DNA strand breaks2012
- Author(s)
  Sakai A, Sakasai R, Kakeji Y, Kitao H, Maehara Y.
- Journal Title
  
  Genes Genetic Systems
  
  Volume: 87(4) Pages: 265-272
- NAID
  10031126619
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] 消化器癌におけるDNA aneuploidy の意義2012
- Author(s)
  安藤　幸滋、趙岩、沖　英次、北尾　洋之、佐伯　浩司、掛地吉　弘、木村　和恵、井田　　智、森田　　勝、楠本　哲也、前原　喜彦
- Journal Title
  
  CYTOMETRY RESEARCH
  
  Volume: 22(2) Pages: 15-20
- NAID
  10031026118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity2012
- Author(s)
  Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yoshinaga K, Saeki H, Morita M, Kakeji Y, Gillespie DA, Yamamoto K, Takata M, Kitao H, Maehara Y.
- Journal Title
  
  DNA Repair
  
  Volume: 11(3) Pages: 247-258
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] FANCJ Expression Predicts the Response to 5-Fluorouracil-Based Chemotherapy in MLH1-Proficient Colorectal Cancer2012
- Author(s)
  Nakanishi R, Kitao H, Fujinaka Y, Yamashita N, Iimori M, Tokunaga E, Yamashita N, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19(11) Pages: 3627-3635
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication.2012
- Author(s)
  Sakasai R., Sakai A., Iimori M., Kiyonari S., Matsuoka K., Kakeji Y., Kitao H., Maehara Y.
- Journal Title
  
  Genes Cells
  
  Volume: 17(12) Issue: 12 Pages: 962-70
- DOI
  10.1111/gtc.12011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24701028
[Journal Article] Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair2012
- Author(s)
  Koichi Sato. Masamichi Ishiai, Kazue Toda, Satoshi Furukoshi, Akihisa Osakabe, Hiroaki Tachiwana, Yoshimasa Takizawa, Wataru Kagawa, Hiroyuki Kitao, Naoshi Dohmae, Chikashi Obuse, Hiroshi Kimura, Minoru Takata, Hitoshi Kurumizaka
- Journal Title
  
  The EMBO Journal
  
  Volume: 31 Issue: 17 Pages: 3524-3536
- DOI
  10.1038/emboj.2012.197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02700, KAKENHI-ORGANIZER-20114001, KAKENHI-PLANNED-20114006, KAKENHI-PROJECT-22370063, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PROJECT-24370071, KAKENHI-PROJECT-24570138, KAKENHI-PROJECT-24870027, KAKENHI-PLANNED-20114005, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23114711, KAKENHI-PUBLICLY-23131505
[Journal Article] Loss of Heterozygosity at BRCA1 locus is significantly associated with aggressiveness and poor prognosis in breast cancer2012
- Author(s)
  Okada S, Tokunaga E, Kitao H, Akiyoshi S, Yamashita N, Saeki H, Oki E, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19 Pages: 1499-507
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Loss of Heterozygosity at BRCA1 Locus Is Significantly Associated with Aggressiveness and Poor Prognosis in Breast Cancer.2012
- Author(s)
  Okada S, Tokunaga E, Kitao H, Akiyoshi S, Yamashita N, Saeki H, Oki E, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: 19 Pages: 1499-507
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer2012
- Author(s)
  Nakanishi, et al
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: (In press) Issue: 11 Pages: 3627-35
- DOI
  10.1245/s10434-012-2349-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338, KAKENHI-PROJECT-23591964, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24591966
[Journal Article] PARP and CSB modulate the processing of transcription-mediated DNA strand breaks.2012
- Author(s)
  Sakai A., Sakasai R., Kakeji Y., Kitao H., Maehara Y.
- Journal Title
  
  Genes Genetic Systems
  
  Volume: 87(4) Pages: 265-72
- NAID
  10031126619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] 胃癌における紡錘体形成チェックポイントタンパク質の発現異常とDNA aneuploidy2012
- Author(s)
  安藤幸滋、北尾洋之、飯森真人、沖英次、佐伯浩司、大賀丈史、掛地吉弘、辻谷俊一、鴻江俊治、前原喜彦
- Journal Title
  
  胃がんperspective
  
  Volume: 5(1) Pages: 24-32
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication2012
- Author(s)
  Sakasai R, Sakai A, Iimori M, Kiyonari S, Matsuoka K, Kakeji Y, Kitao H, Maehara Y.
- Journal Title
  
  Genes Cells
  
  Volume: 17(12) Pages: 962-970
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers.2012
- Author(s)
  Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Breast Cancer.
  
  Volume: 19 Pages: 161-9
- NAID
  10030981059
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers.2011
- Author(s)
  Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume: (In press)
- NAID
  10030981059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] FancJ/Brip1 helicase protects against genomic losses and gains invertebrate cells2011
- Author(s)
  Kitao, et al
- Journal Title
  
  Genes to Cells
  
  Volume: 16 Issue: 6 Pages: 717-724
- DOI
  10.1111/j.1365-2443.2011.01523.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
[Journal Article] Fanconi anemia : a disorder defective in the DNA damage response2011
- Author(s)
  Kitao, Takata
- Journal Title
  
  International Journal of Hematology
  
  Volume: 93 Issue: 4 Pages: 417-424
- DOI
  10.1007/s12185-011-0777-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23651046
[Journal Article] Evaluation of homologous recombinational repair in chicken Blymphoma cell line, DT402011
- Author(s)
  Kitao, et al
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 745 Pages: 293-309
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] Fanconi anemia : a disorder defective in the DNA damage response.2011
- Author(s)
  Kitao H, Takata M
- Journal Title
  
  Int J Hematology
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer2010
- Author(s)
  Ando K, Kakeji Y, Kitao H, Iimori M, Zhao Y, Yoshida R, Oki E, Yoshinaga K, Matumoto T, Morita M, Sakaguchi Y, Maehara Y
- Journal Title
  
  Cancer Science Epub
- NAID
  10026589263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers2010
- Author(s)
  Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Breast Cancer
- NAID
  10030981059
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes.2010
- Author(s)
  Wu Y, Sommers JA, Suhasini AN, Leonard T, Deakyne JS, Mazin AV, Shin-Ya K, Kitao H, Brosh RM Jr.
- Journal Title
  
  Blood
  
  Volume: 116 Pages: 3780-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer2010
- Author(s)
  Tokunaga E, Okada S, Kitao H, Shiotani S, Saeki H, Endo K, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Breast Cancer Epub
- NAID
  10029407629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] The Fanconi anemia pathway : Insights from somatic cell genetics using DT40 cell line. Invited review.2009
- Author(s)
  Takata M, Ishiai M, Kitao H
- Journal Title
  
  Mutation Research Fanconi anemia special Issue (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Insights from somatic cell genetics using DT40 cellline. Invited review2009
- Author(s)
  Takata M, Ishiai M, Kitao H., et.al.
- Journal Title
  
  Mutation Research Fanconi anemia Special Issue(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] TheFanconi anemia pathway: Insights from somatic cell genetics using DT40 cell line.2009
- Author(s)
  Takata M., Ishiai M., Kitao H.
- Journal Title
  
  Invited review. Mutat. Res. 668
  
  Pages: 92-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] The Fanconi anemia pathway : Insights from somatic cell genetics using DT40 cell line.2009
- Author(s)
  Takata M, Ishiai M, Kitao H
- Journal Title
  
  Mutat Res 668
  
  Pages: 92-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] ファンコニ貧血とDNA損傷応答ネットワーク2009
- Author(s)
  松下暢子、北尾洋之、石合正道、高田穣
- Journal Title
  
  蛋白質核酸酵素 54
  
  Pages: 580-585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] The Fanconi anemia pathway : insights from somatic cell genetics using DT40 cell line2009
- Author(s)
  Takata M, Iahiai M, Kitao H.
- Journal Title
  
  Mutation Research 668
  
  Pages: 92-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] ファンコニ貧血とゲノム不安定性2009
- Author(s)
  北尾洋之、藤中良彦、久保信英、中ノ子智徳、吉永敬士、徳永えり子、佐伯浩司、遠藤和也、森田勝、掛地吉弘、前原喜彦
- Journal Title
  
  福岡医学雑誌 99
  
  Pages: 115-122
- NAID
  120000981513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR muation2008
- Author(s)
  Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Science 98
  
  Pages: 357-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway2008
- Author(s)
  Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, Saberi A, Kinoshita E, Kinoshita Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M.
- Journal Title
  
  Nat Struct Mol Biol 15(11)
  
  Pages: 1138-46
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] FANCI phosphorylation functions as a molecular switchto turn on the Fanconi anemia pathway2008
- Author(s)
  Ishiai Kitao H, Smogorzewska A, Tomida J, Kinomura A, et.al.
- Journal Title
  
  Nat Struct Mol Biol 15
  
  Pages: 1138-1146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion2008
- Author(s)
  Kitao H, Kimura M, Yamamoto K, Seo H, Namikoshi K, Agata Y, Ohta K, Takata M.
- Journal Title
  
  Int Immunol 20(2)
  
  Pages: 277-84
- NAID
  10021239538
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway2008
- Author(s)
  Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, Saberi A, Kinoshita E, Kinoshita Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M
- Journal Title
  
  Nature Structural and Molecular Biology 15
  
  Pages: 1138-1146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.2008
- Author(s)
  Ishiai M, Kitao H, Elledge SJ, Takata M., et al
- Journal Title
  
  Nat Struct Mol Biol. 15
  
  Pages: 1138-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.2008
- Author(s)
  Kitao H., Kimura M., Yamamoto K., Seo H., Namikoshi K., Agata Y., Ohta K., Takata M.
- Journal Title
  
  Int. Immunol. 20
  
  Pages: 277-284
- NAID
  10021239538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Detection of phosphorylation on large proteins by western blotting using Phos-tag containing gel.2008
- Author(s)
  Tomida J., Kitao H., Kinoshita E., Takata., M.
- Journal Title
  
  Nature Protocols 232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in immunoglobulin gene conversion.2008
- Author(s)
  Kitao, H., Kimura, M., Yamamoto, K., Seo, H., Namikoshi, K., Agata, Y., Ohta, K., and Takata, M.
- Journal Title
  
  International Immunology 20
  
  Pages: 277-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.2008
- Author(s)
  Kitao H, et. al.
- Journal Title
  
  Int Immunology 20
  
  Pages: 277-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion2008
- Author(s)
  Kitao H, Kimura M, Yamamoto K, Seo H, Namikoshi K, Agata Y, Ohta K, Takata M
- Journal Title
  
  International Immunology 20
  
  Pages: 277-284
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.2008
- Author(s)
  Kitao H, et. al.
- Journal Title
  
  Int Immunology 20
  
  Pages: 277-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway2008
- Author(s)
  Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, SaberiA, Kinoshita E, Kinoshita-Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M
- Journal Title
  
  Nature Structural and Molecular Biology 15
  
  Pages: 1138-1146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.2008
- Author(s)
  Ishiai M., Kitao H., Smogorzewska A., Tomida J., Kinomura A., Uchida E., Saberi A., Kinoshita E., Kinoshita-Kikuta E., Koike T., Tashiro S., Elledge S.J., Takata M.
- Journal Title
  
  Nat. Struc. Mol. Biol. 15
  
  Pages: 1138-1146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] ファンコニ貧血とゲノム不安定2008
- Author(s)
  北尾洋之、藤中良彦、久保信英、中ノ子智徳、吉永士、徳永えり子、佐伯浩司、遠藤和也、森田勝、掛地吉弘、前原喜彦
- Journal Title
  
  福岡医学雑誌 99
  
  Pages: 115-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non Small Cell Lung Cancer Cell Line.2007
- Author(s)
  Ogino A., Kitao H., A., Ishiai M., Kozuki T., Takigawa N., Hirano S., Uchida Takata M., Kiura K., Tanimoto M.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 7807-7014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] ファンコニ貧血の分子機構2007
- Author(s)
  北尾洋之, 高田穣
- Journal Title
  
  最新医学 62・2
  
  Pages: 112-117
- NAID
  40015288565
- Data Source
  KAKENHI-PROJECT-17790218
[Journal Article] Emergence of epidermal growth factor receptor T790M mutation during chronicexposure to gefitinib in a non small cell lung cancer cell line.2007
- Author(s)
  Ogino, A., Kitao, H., Hirano, S., Uchida, A., Ishiai, M., Kozuki, T., Takigawa, N., Takata, M., Kiura, K., and Tanimoto, M.
- Journal Title
  
  Cancer Research 67
  
  Pages: 7807-7814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] A requirement of FancL and FancD2 monoubiquitination in DNA repair.2007
- Author(s)
  Seki S., Ohzeki M., Uchida A., Hirano S., Matsushita N., Kitao H., Oda T., Yamashita T., Kashihara N., Tsubahara A., Takata M., Ishiai M.
- Journal Title
  
  Genes Cells 12
  
  Pages: 299-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib-resistance in cells carrying EGFR mutation.2007
- Author(s)
  Uchida A, Hirano S, Kitao H, Ogino A, Rai K, Toyooka S, Takigawa N, Tabata M, Takata M, Kiura K, Tanimoto M.
- Journal Title
  
  Cancer Sci. 98(3)
  
  Pages: 357-63
- NAID
  10019481589
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Fanconi Anemia : genetic analysis of a human disease using chicken system2007
- Author(s)
  Takata M, Kitao H, Ishiai M
- Journal Title
  
  Cytogenetic and Genome Research 117
  
  Pages: 346-351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] genetic analysis of a human disease using chicken system.2007
- Author(s)
  Takata M, Kitao H, Ishiai M. Fanconianemia
- Journal Title
  
  Cytogenet Genome Res. 117
  
  Pages: 346-351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] A requirement of FancL and FancD2 monoubiquitination in DNA repair.2007
- Author(s)
  Seki S, Ohzeki M, Uchida A, Hirano S, Matsushita N, Kitao H, Oda T, Yamashita T, Kashihara N, Tsubahara A, Takata M, Ishiai M.
- Journal Title
  
  Genes Cells. 12(3)
  
  Pages: 299-310
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] ファンコニ貧血の分子機構2007
- Author(s)
  北尾洋之、高田穣
- Journal Title
  
  最新医学 62
  
  Pages: 112-117
- NAID
  40015288565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non Small Cell Lung Cancer Cell Line2007
- Author(s)
  Ogino A, Kitao H, Hirano S, Uchida A, Ishiai M, Kozuki T, Takigawa N, Takata M, Kiura K, Tanimoto M
- Journal Title
  
  Cancer Res. 67(16)
  
  Pages: 7807-14
- Data Source
  KAKENHI-PROJECT-19390087
[Journal Article] Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non small cell lung cancer cell line2007
- Author(s)
  Ogino A, Kitao H, Hirano S, Uchida A, Ishiai M, Kozuki T, Takigawa N, Takata M, Kiura K, Tanimoto M.
- Journal Title
  
  Cancer Research 67
  
  Pages: 7807-7814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] A requirement of FancL and FancD2 monoubiquitination in DNA repair2007
- Author(s)
  Seki S, Ohzeki M, Uchida A, Hirano S, Matsushita N, Kitao H, Oda T, Yamashita T, Kashihara N, Tsubahara A, Takata M, Ishiai M
- Journal Title
  
  Genes to Cells 12
  
  Pages: 299-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790234
[Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006
- Author(s)
  Kitao H., Yamamoto K., Matsushita N., Ohzeki M., Ishiai M., Takata M.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 21312-21320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Functional interplay between BRCA2/FANCDI and FANCC in DNA repair.2006
- Author(s)
  Kitao H, Yamanioto K. et al.
- Journal Title
  
  Journal of Biological Chemistry 281・302
  
  Pages: 21312-21320
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006
- Author(s)
  Kitao H, Yamamoto K, etal.
- Journal Title
  
  Journal of Biological Chemistry 281・301
  
  Pages: 21312-21320
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Functional interplay between BRCA2/FancD2 and FancC in DNA repair.2006
- Author(s)
  Kitao H, Yamamoto K, et al.
- Journal Title
  
  Journal of Biological Chemistry 281・30
  
  Pages: 21312-21320
- Data Source
  KAKENHI-PROJECT-17790218
[Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006
- Author(s)
  Kitao H, Yamamoto K, Matsushita N, Ohzeki M, Ishiai M, Takata M.
- Journal Title
  
  J Biol Chem. 281(30)
  
  Pages: 21312-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Functional interplay between BRCA2/FANCD1 and FANCC in DNA repair.2006
- Author(s)
  Kitao H, Yamamoto K, et al.
- Journal Title
  
  Journal of Biological Chemistry 281・302
  
  Pages: 21312-21320
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] DNA修復における家族性乳ガン遺伝子BRCA2とファンコニ貧血経路との機能的連携2006
- Author(s)
  北尾洋之
- Journal Title
  
  放射線生物研究 41・2
  
  Pages: 137-153
- NAID
  40007359881
- Data Source
  KAKENHI-PROJECT-17790218
[Journal Article] A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair.2005
- Author(s)
  Matsushita N., Kitao H., Ishiai M., Nagashima N., Hirano S., Okawa K., Ohta T., Yu D.S., McHugh P.J., Hickson I.D., Venkitaraman A.R., Kurumizaka H., Takata M.
- Journal Title
  
  Mol. Cell 19
  
  Pages: 841-847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013083
[Journal Article] A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair.2005
- Author(s)
  Matsushita N, Kitao H, Ishiai M, Nagashima N, Hirano S, Okawa K, Ohta T, Yu DS, McHugh PJ, Hickson ID, Venkitaraman AR, Kurumizaka H, Takata M.
- Journal Title
  
  Mol Cell. 19(6)
  
  Pages: 841-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590279
[Journal Article] Copy-neutral loss of heterozygosity at the p53 locus in carcinogenesis of esophageal squamous cell carcinomas associated with p53 mutations
- Author(s)
  Saeki H, Kitao H, Yoshinaga K, Nakanoko T, Kubo N, Kakeji Y, Morita M, Maehara Y.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 17(7) Pages: 1731-40
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes
- Author(s)
  Wu Y, Sommers JA, Suhasini AN, Leonard T, Deakyne JS, Mazin AV, Shin-Ya K, Kitao H, Brosh RM Jr
- Journal Title
  
  Blood
  
  Volume: 116(19) Pages: 3780-91
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] Maehara Y. FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer
- Author(s)
  Nakanishi R, Kitao H, Fujinaka Y, Yamashita N, Iimori M, Tokunaga E, Yamashita N, Morita M, Kakeji Y
- Journal Title
  
  Annals of Surgical Oncology(2012) in press.
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] Fanconi anemia : a disorder defective in the DNA damage response
- Author(s)
  Kitao H, Takata M
- Journal Title
  
  International Journalof Hematology
  
  Volume: 4 Pages: 417-24
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] 消化器癌におけるDNA aneuploidyの意義
- Author(s)
  安藤幸滋、趙岩、沖英次、北尾洋之、佐伯浩司、掛地吉弘、木村和恵、井田智、森田勝、楠本哲也、前原喜彦
- Journal Title
  
  CYTOMETRY RESEARCH
  
  Volume: 22(2) Pages: 15-20
- NAID
  10031026118
- Data Source
  KAKENHI-PROJECT-23591964
[Journal Article] Maehara Y. ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity
- Author(s)
  Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yoshinaga K, Saeki H, Morita M, Kakeji Y, Gillespie DA, Yamamoto K, Takata M, Kitao H
- Journal Title
  
  DNA Repair(Amst)
  
  Volume: 11(3) Pages: 247-58
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer
- Author(s)
  Ando K, Kakeji Y, Kitao H, Iimori M, Zhao Y, Yoshida R, Oki E, Yoshinaga K, Matumoto T, Morita M, Sakaguchi Y, Maehara Y
- Journal Title
  
  Cancer Science
  
  Volume: 101(3) Pages: 639-45
- NAID
  10026589263
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer
- Author(s)
  Tokunaga E, Okada S, Kitao H, Shiotani S, Saeki H, Endo K, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Breast Cancer
  
  Volume: 18(2) Pages: 120-3
- NAID
  10029407629
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] Maehara Y. FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer
- Author(s)
  Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yoshinaga K, Saeki H, Morita M, Kakeji Y, Gillespie DA, Yamamoto K, Takata M, Kitao H
- Journal Title
  
  Annals of Surgical Oncology(2012) in press
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells
- Author(s)
  Kitao H, Nanda I, Sugino RP, Kinomura A, Yamazoe M, Arakawa H, Schmid M, Innan H, Hiom K, Takata M
- Journal Title
  
  Genes to Cells(2011)
  
  Volume: 16(6) Pages: 714-27
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] Evaluation of homologous recombinational repair in chicken B lymphoma cell line
- Author(s)
  Kitao H, Hirano S, Takata M.
- Journal Title
  
  DT40. Methods Mol Biol
  
  Volume: 745
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] The Fanconi anemia pathway : insights from somatic cell genetics using DT40 cell line
- Author(s)
  Takata M, Ishiai M, Kitao H
- Journal Title
  
  Mutation Research
  
  Volume: 668(1-2) Pages: 92-102
- Data Source
  KAKENHI-PROJECT-21590338
[Patent] 検出剤、該検出剤を含むキット、被験試料中のＤＮＡに取り込まれたトリフルリジンを検出する方法およびトリフルリジンまたはトリフルリジンを含む抗悪性腫瘍剤の抗腫瘍効果を判定する方法2015
- Inventor(s)
  北尾洋之、諸富洋介、木庭守、前原喜彦
- Industrial Property Rights Holder
  北尾洋之、諸富洋介、木庭守、前原喜彦
- Industrial Property Rights Type
  特許
- Filing Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460390
[Presentation] p53機能欠損細胞におけるトリフルリジン誘導性DNA複製ストレスによる細胞毒性効果のメカニズム Mechanisms of cytotoxicity of trifluridine-induced DNA replication stress in p53 deficient cells2024
- Author(s)
  飯森真人，若狹武司，野中謙太朗，菊竹智恵，須山幹太，小武内尚，松岡和明，沖英次，前原喜彦，北尾洋之
- Organizer
  第83回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19577
[Presentation] The significance of ATR as a therapeutic target in combination with DNA replication stress-inducing drugs2023
- Author(s)
  北尾洋之、野中謙太朗、飯森真人、沖英次
- Organizer
  19th Ataxia Telagiectasia Workshop
- Data Source
  KAKENHI-PROJECT-22K19577
[Presentation] The significance of ATR as a therapeutic target in combination with DNA replication stress-inducing drugs2023
- Author(s)
  北尾洋之、野中謙太朗、飯森真人、沖英次
- Organizer
  19th Ataxia Telagiectasia Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24030
[Presentation] DNA複製ストレス誘導性抗がん剤との併用における治療標的としてのATR制御の意義2022
- Author(s)
  野中謙太朗、飯森真人、北尾洋之
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24030
[Presentation] DNA複製ストレス誘導性抗がん剤との併用における治療標的としてのATR制御の意義2022
- Author(s)
  野中謙太朗、飯森真人、北尾洋之
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19577
[Presentation] p53機能欠損細胞におけるトリフルリジン誘導性DNA複製ストレスによる細胞毒性効果のメカニズム2022
- Author(s)
  飯森真人、若狹武司、野中謙太朗、菊竹千恵、須山幹太、小武内尚、松岡和明、沖英次、前原喜彦、北尾洋之
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24030
[Presentation] DNA複製ストレス誘導性抗がん剤との併用における治療標的としてのATR制御の意義2022
- Author(s)
  飯森真人、野中謙太朗、北尾洋之
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24030
[Presentation] DNA複製ストレス誘導性抗がん剤との併用における治療標的としてのATR制御の意義2022
- Author(s)
  飯森真人、野中謙太朗、北尾洋之
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19577
[Presentation] p53機能欠損細胞におけるトリフルリジン誘導性DNA複製ストレスによる細胞毒性効果のメカニズム2022
- Author(s)
  飯森真人、若狹武司、野中謙太朗、菊竹千恵、須山幹太、小武内尚、松岡和明、沖英次、前原喜彦、北尾洋之
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19577
[Presentation] Tracing trifluridine in the DNA using anti-BrdU antibodies2019
- Author(s)
  北尾洋之、藤本禎明、中西良太、糠塚守、松岡和明、武知貞士、若狹武司、飯森真人、森正樹
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19478
[Presentation] トリフルリジン誘導性細胞老化とDNA複製ストレスとの関連2019
- Author(s)
  北尾洋之、片岡裕貴、飯森真人、若狹武司、藤澤遼、釣本敏樹、松岡和明、沖英次、佐伯浩司、前原喜彦、森正樹
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-18K19478
[Presentation] Cell fate decision according to p53 status in response to nucleoside analog-induced DNA replication stress2018
- Author(s)
  Hiroyuki Kitao
- Organizer
  Gordon Research Conference-Mutagenesis
- Data Source
  KAKENHI-PROJECT-17H03598
[Presentation] Cell fate decision according to p53 status in response to nucleoside analog-induced DNA replication stress2018
- Author(s)
  Hiroyuki Kitao
- Organizer
  Gordon Research Conference-Mutagenesis
- Data Source
  KAKENHI-PROJECT-18K19478
[Presentation] Cell fate decision according to p53 status in response to nucleoside analog-induced DNA replication stress2018
- Author(s)
  Hiroyuki Kitao
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03598
[Presentation] Cell fate decision according to p53 status in response to nucleoside analog-induced DNA replication stress2018
- Author(s)
  Hiroyuki Kitao
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19478
[Presentation] The mechanism of tumor cell fate decision by an antitumor nucleoside analogue, trifluridine2018
- Author(s)
  Hiroyuki Kitao
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19478
[Presentation] The mechanism of tumor cell fate decision by an antitumor nucleoside analogue, trifluridine2018
- Author(s)
  Hiroyuki KItao
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03598
[Presentation] トリフルリジン誘導性DNA複製ストレスががん細胞の運命に及ぼす影響2017
- Author(s)
  北尾洋之、片岡裕貴、飯森真人、藤澤遼、釣本敏樹、一瀬智美、三浦大典、松岡和明、沖英次、佐伯浩司、前原喜彦
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03598
[Presentation] トリフルリジン・チピラシルによる治療効果の基礎・臨床での評価2017
- Author(s)
  北尾洋之、飯森真人、中西良太、佐伯浩司、沖英次、前原喜彦
- Organizer
  第35回日本ヒト細胞学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03598
[Presentation] Replicative stress in the induction of p53-dictated cytotoxicity by an antitumor nucleoside analogue, trifluridine.2017
- Author(s)
  北尾洋之、片岡裕貴、飯森真人、藤澤遼、釣本敏樹、一瀬智美、三浦大典、松岡和明、沖英次、佐伯浩司、前原喜彦
- Organizer
  29th Fanconi Anemia Research Fund Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03598
[Presentation] ヌクレオチドアナログ誘導性DNA複製ストレスとp53を介した細胞運命2017
- Author(s)
  北尾洋之、飯森真人、片岡裕貴、藤澤遼、釣本敏樹、一瀬智美、三浦大典、若狹武司、松岡和明、佐伯浩司、沖英次、前原喜彦
- Organizer
  第40回日本分子生物学会総会
- Data Source
  KAKENHI-PROJECT-17H03598
[Presentation] トリフルリジン誘導性DNA複製ストレスががん細胞の運命に及ぼす影響2017
- Author(s)
  北尾洋之、片岡裕貴、飯森真人、藤澤遼、釣本敏樹、一瀬智美、三浦大典、松岡和明、沖英次、佐伯浩司、前原喜彦
- Organizer
  第21回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-17H03598
[Presentation] Clinical impact of the expression of polymeraseθ in breast cancer2016
- Author(s)
  Eriko Tokunaga, Yuka Inoue, Nami Yamashita, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] Clinical impact of the expression of APOBEC3B in breast cancer2015
- Author(s)
  Eriko Tokunaga, Nami Yamashita, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] 食道扁平上皮癌におけるMTH1発現のバイオマーカーとしての意義2015
- Author(s)
  佐伯浩司、秋山真吾、北尾洋之、西村　章、工藤健介、中司　悠、田尻裕匡、堤　智崇、由茅隆文、笠木勇太、杉山雅彦、中島雄一郎、大垣吉平、園田英人、沖　英次、前原喜彦
- Organizer
  第26回日本消化器癌発生学会総会
- Place of Presentation
  鳥取
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] The 1,2-diaminocyclohexane carrier ligand in oxaliplatin induces p53-dependent transcriptional repression of factors involved in thymidylate biosynthesis2015
- Author(s)
  北尾洋之
- Organizer
  27th AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Place of Presentation
  Hynes Convention Center, Boston, MA, USA
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460390
[Presentation] Cellular response to a fluorinated thymidine analogue trifluridine, a key component of the novel oral antitumor drug TAS-102.2015
- Author(s)
  Kitao H., Matsuoka K., Iimori M., Niimi S., Watanabe S., Kiniwa M,, Maehara Y.
- Organizer
  Gordon Research Conference on Nucleosides, Nucleotides and Oligonucleotides, Newport, Rhode Island
- Place of Presentation
  USA
- Year and Date
  2015-06-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] 新規経口ヌクレオシド型抗腫瘍薬「ロンサーフ」の作用機序2015
- Author(s)
  北尾　洋之
- Organizer
  九州大学先端融合医療レドックスナビ研究拠点若手研究者主催シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2015-01-27
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] Cellular response to a fluorinated thymidine analogue trifluridine, a key component of the novel oral antitumor drug TAS-1022015
- Author(s)
  北尾洋之
- Organizer
  Gordon Research Conference on Nucleosides, Nucleotides and Oligonucleotides
- Place of Presentation
  Salva Regina University, Newport, RI, USA
- Year and Date
  2015-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460390
[Presentation] 新規経口ヌクレオシド系抗悪性腫瘍剤TAS-102の抗がん作用機序解析2015
- Author(s)
  北尾　洋之、松岡　和明、新美晋一郎、飯森　真人、渡邉すぎ子、木庭　　守、佐伯　浩司、沖　　英次、前原　喜彦
- Organizer
  第19回日本がん分子標的治療学会学術集会
- Place of Presentation
  松山
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] Trifluridine induces p53-dependent sustained G2 phase arrest with its massive misincorporation into DNA and few DNA strand breaks2015
- Author(s)
  Kazuaki Matsuoka, Hiroyuki Kitao
- Organizer
  American Association of Cancer Research (AACR) Annual Meeting 2015
- Place of Presentation
  Philadelphia, PA
- Year and Date
  2015-04-20
- Data Source
  KAKENHI-PROJECT-25460390
[Presentation] 食道扁平上皮癌におけるMTH1発現のバイオマーカーとしての意義2015
- Author(s)
  佐伯　浩司、秋山　真吾、北尾　洋之、西村　　章、工藤　健介、中司　　悠、田尻　裕匡、堤　　智崇、由茅　隆文、笠木　勇太、杉山　雅彦、中島雄一郎、大垣　吉平、園田　英人、沖　　英次、前原　喜彦
- Organizer
  第26回日本消化器癌発生学会総会
- Place of Presentation
  米子
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] トリフルリジンはDNAに取り込まれ、p53依存的なG2期停止を引き起こす2015
- Author(s)
  北尾　洋之、松岡　和明、飯森　真人、新美晋一郎、渡邊すぎ子、佐伯　浩司、沖　　英次、前原　喜彦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] Cellular response to a fluorinated thymidine analogue trifluridine, a key component of the novel oral antitumor drug TAS-1022015
- Author(s)
  Kitao H., Matsuoka K., Iimori M., Niimi S., Watanabe S.Kiniwa M., Maehara Y.
- Organizer
  Gordon Research Conference
- Place of Presentation
  Rockport, RI, USA
- Year and Date
  2015-06-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] The 1,2-diaminocyclohexane carrier ligand in oxaliplatin induces p53-dependent transcriptional repression of factors involved in thymidylate biosynthesis.2015
- Author(s)
  Kitao H., Kiyonari S., Iimori M., Matsuoka K., Morikawa-Ichinose T., Miura D., Niimi S., Saeki H., Oki E., Maehara Y.
- Organizer
  AACR-NCI-EORTC International Conference – Molecular Targets and Cancer Therapeutics
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05792
[Presentation] The 1,2-diaminocyclohexane carrier ligand in oxaliplatin induces p53-dependent transcriptional repression of factors involved in thymidylate biosynthesis2015
- Author(s)
  Kitao H., Kiyonari S, Iimori M, Matsuoka K, Morikawa-Ichinose T, Miura D, Niimi S, Saeki H, Oki E, Maehara Y.
- Organizer
  27th AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Boston, Massachusetts
- Place of Presentation
  USA
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] 新規経口ヌクレオシド型抗腫瘍薬「ロンサーフ」の作用機序2015
- Author(s)
  北尾　洋之
- Organizer
  九州大学先端融合医療レドックスナビ研究拠点若手研究者主催シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2015-01-27
- Invited
- Data Source
  KAKENHI-PROJECT-25460390
[Presentation] Analysis of KRAS/NRAS, PI3CA and BRAF mutations in the phase 2 KSCC0901 study of cetuximab + s-1 as 3rd-line treatment for metastatic colorectal cancer in Japanese patients2014
- Author(s)
  Yasunori Emi, Eiji Oki, Hiroshi Saeki, Hiroyuki Kitao, Hironori Samura, Takao Takahashi, Terumitsu Sawai, Yoshito Akagi, Akihito Tsuji, Susumu Eguchi, Kazuhiro Yoshida, Hideo Baba, Yutaka Ogata, Shoji Natsugoe, Mototugu Shimokawa, Yoshihiko Maehara
- Organizer
  ASCO-GI
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-25462059
[Presentation] Aurora BおよびCDK1による微小管結合因子EB2の制御機構2013
- Author(s)
  飯森　真人、北尾　洋之、渡邊すぎ子、前原　喜彦
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] Subtype specific chromosomal aberrations in breast cancer2013
- Author(s)
  Eriko Tokunaga, Nami Yamashita, Kimihiro Tanaka, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Masaru Morita, Yoshihiko Maehara
- Organizer
  San Antonio Breast Cancer Symposium 2013
- Place of Presentation
  San Antonio
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] Trifluorothymidine induces p53-dependent sustained G2 arrest without extensive DNA strand-breaks2013
- Author(s)
  Kazuaki Matsuoka, Makoto Iimori, Hiroshi Tsukihara, Shinichi Kiyonari, Sugiko Watanabe, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
- Organizer
  第３６回日本分子生物学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25460390
[Presentation] Subtype specific chromosomal aberrations in breast cancer2013
- Author(s)
  Tokunaga E, Yamashita N, Tanaka K, Saeki H, Oki E, Kitao H, Morita M, Maehara Y
- Organizer
  San Antonio Breast Cancer Symposium 2013
- Place of Presentation
  サンアントニオ
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] Subtype specific chromosomal aberrations in breast cancer2013
- Author(s)
  Eriko Tokunaga, Nami Yamashita, Kenji Taketani, Koji Ando, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Masaru Morita, Yoshihiko Maehara
- Organizer
  第72回　日本癌学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 食道癌におけるLINE-1メチル化の検討2013
- Author(s)
  河野　浩幸、北尾　洋之、日高　　元、笠木　勇太、津田　康雄、由茅　隆文、大津　　甫、武谷　憲二、安藤　幸滋、井田　　智、木村　和恵、佐伯　浩司、沖　　英次、森田　　勝、楠本　哲也、前原　喜彦
- Organizer
  第67回日本食道学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] Rad9, Rad17, TopBP1 and Claspin Play Essential Roles in Heat-Induced Activation of ATR Kinase and Heat Tolerance.2013
- Author(s)
  Tuul M., Kitao H., Matsuoka K., Iimori M., Kiyonari S., Yamamoto K., Morita M., Maehara Y.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] トリフルオロチミジンによるピリミジン代謝経路への影響とDNA損傷応答2013
- Author(s)
  松岡　和明、飯森　真人、月原　宏志、清成　信一、渡邊すぎ子、徳永えり子、沖　　英次、北尾　洋之、前原　喜彦
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] Subtype specific chromosomal aberrations in breast cancer2013
- Author(s)
  Tokunaga E, Yamashita N, Taketani K, Ando K, Saeki H, Oki E, Kitao H, Morita M, Maehara Y
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer.2012
- Author(s)
  Nakanishi R., Kitao H., Fujinaka Y., Yamashita N., Iimori M., Tokunaga E., Yamashita N., Morita M., Kakeji Y., Maehara Y.
- Organizer
  The 8th International Symposium on Cancer Research and Therapy
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591964
[Presentation] Significance of mortalin expression in gastric cancer with normal p532012
- Author(s)
  Ando K, Oki E, Yan Z, Kitao H, Saeki H, Ohga T, Kakeji Y, Tujitani S, Kohnoe S, Maehara Y.
- Organizer
  ASCO GI 2012
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-23591964
[Presentation] 大腸癌におけるKRAS, BRAF変異とマイクロサテライト不安定性2012
- Author(s)
  中西良太、趙岩、北尾洋之、安藤幸滋、佐伯浩司、大賀丈史、沖英次、掛地吉弘、辻谷俊一、鴻江俊治、前原喜彦
- Organizer
  第45回制癌剤適応研究会
- Place of Presentation
  東京
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PROJECT-23591964
[Presentation] 胃癌におけるDNA ploidyと紡錘体形成チェックポイントタンパク質BUBR1の発現2012
- Author(s)
  安藤　幸滋、掛地　吉弘、中西　良太、久松　雄一、北尾　洋之、佐伯　浩司、沖　　英次、大賀　丈史、辻谷　俊一、鴻江　俊治、前原　喜彦
- Organizer
  第21回日本癌転移学会学術集会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23591964
[Presentation] 胃癌におけるDNA ploidyと紡錘体形成チェックポイントタンパク質BUBR1の発現2012
- Author(s)
  安藤幸滋、掛地吉弘、中西良太、久松雄一、北尾洋之、佐伯浩司、沖英次、大賀丈史、辻谷俊一、鴻江俊治、前原喜彦
- Organizer
  第21回日本癌転移学会学術集会総会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23591964
[Presentation] ATR-Chk1 signaling pathway arid homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity.2012
- Author(s)
  Kitao H
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  ロイトン札幌(札幌)
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] 大腸癌におけるDNA修復因子FANCJ発現と5-FU感受性2012
- Author(s)
  中西良太、北尾洋之、藤中良彦、安藤幸滋、佐伯浩司、大賀丈史、徳永えり子、沖英次、掛地吉弘、辻谷俊一、鴻江俊治、前原喜彦
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-23591964
[Presentation] Functional role of FancJ in the cellular response to 5-FU-induced DNA damage.2012
- Author(s)
  Kitao H
- Organizer
  第35回日本分子生物学会総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] 大腸癌におけるDNA修復因子FANCJの発現と5-FU感受性2012
- Author(s)
  中西　良太、北尾　洋之、秋吉清百合、安藤　幸滋、佐伯　浩司、大賀　丈史、徳永えり子、沖　　英次、掛地　吉弘、辻谷　俊一、鴻江　俊治、前原　喜彦
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23591964
[Presentation] Significance of mortalin expression in gastric cancer with normal p532012
- Author(s)
  Ando K,. Oki E., Yan Z., Kitao H., Saeki H., Ohga T., Kakeji Y., Tujitani S., Kohnoe S., Maehara Y.
- Organizer
  ASCO GI
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-23591964
[Presentation] Hyperthermia activates both ATM and ATR signaling pathways for cell tolerance against heat.2012
- Author(s)
  Kitao H
- Organizer
  The 11^<th> International Congress of Hyperthermic Oncology, The 29^<th> Japanese Congress of Thermal Medicine Joint meeting 2012
- Place of Presentation
  ハイアットリージェンシー京都
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation]2012
- Author(s)
  Nakanishi R, Kitao H, Fujinaka Y, Yamashita N, Iimori M, Tokunaga E, Yamashita N, Morita M, Kakeji Y, Maehara Y.
- Organizer
  The 8th International Symposium on Cancer Research and Therapy
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591964
[Presentation] Different impact of the loss of heterozygosity at BRCA1 and BRCA2 loci on clinicopathological features of breast cancer2011
- Author(s)
  Tokunaga E, Okada S, Akiyoshi S, Yamashita N, Ando N, Saeki H, Oki E, Ohga T, Kitao H, Kakeji Y, Maehara Y
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 5-FUにより誘起されるDNA損傷に対する細胞応答機構2011
- Author(s)
  北尾洋之、藤中良彦、飯森真人、ムンフボルド・トール、中西良太、山下奈真、松岡和明、掛地吉弘、前原喜彦
- Organizer
  第15回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] Involvement of FancJ and Msh2 in the cellular response to 5-FU-induced DNA damages2011
- Author(s)
  Kitao, et al
- Organizer
  23^<rd> Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  スペイン・バルセロナ
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells2011
- Author(s)
  Kitao, et al
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] Homologous recombinational repair and Chk1-mediated S phase arrest protect cells from 5-FU cytotoxicity2011
- Author(s)
  Kitao H, Fujinaka Y, Matsuoka K, Iimori M, Tuul M, Sakasai R, Yamamoto K, Takata M, Kakeji Y, Maehara Y
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] 家族性乳がん遺伝子FancJ/Brip1ヘリカーゼ欠損によって起こる大規模ゲノム欠失・増幅2011
- Author(s)
  北尾洋之、高田穣、前原喜彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] Chk1-mediated S phase arrest and homologous recombinational repair protect cells from 5-FU cytotoxicity2011
- Author(s)
  Kitao, et al
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] Involvement of FancJ and Msh2 in the cellular response to 5-FU-induced DNA damages2011
- Author(s)
  Kitao H, Nakanishi R, Iimori M, Fujinaka Y, Tuul M, Yamashita N, Takata M, Kakeji Y, Maehara Y
- Organizer
  23rd Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  スペイン・バルセロナ
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] 5-FUにより発生するDNA損傷に対する細胞応答機構2011
- Author(s)
  北尾洋之, 他
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] Possible contribution of FancJ in the repair process of 5-FU-induced DNA damages2010
- Author(s)
  Kitao H, Nakanishi R, Iimori M, Fujinaka Y, Tuul M, Yamashita N, Takata M, Kakeji Y, Maehara Y
- Organizer
  22^<nd> Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  米国ミネアポリス
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] 5-FUによるファンコニ貧血経路活性化のメカニズム2010
- Author(s)
  北尾洋之、藤中良彦、飯森真人、ムンフボルド・トール、中西良太、山下奈真、久保信英、吉永敬士、徳永えり子、森田勝、掛地吉弘、前原喜彦
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] 5-FUによるファンコニ貧血経路活性化におけるChk1の役割2010
- Author(s)
  北尾洋之、飯森真人、ムンフボルド・トール、藤中良彦、久保信英、中西良太、山下奈真、吉永敬士、徳永えり子、森田勝、掛地吉弘、前原喜彦
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] GENOME INSTABILITY PHENOTYPES INDUCED BY LOSS OF FANCJ/BRIP1 FUNCTION2010
- Author(s)
  Kitao H, Nanda I, Kakeji Y, Maehara Y, Takata M
- Organizer
  100^<th> Annual Meeting American Association for Cancer Research
- Place of Presentation
  米国デンバー
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] A novel role of FancJ in the cellular response to 5-FU-induced DNA damages2010
- Author(s)
  Kitao H, Nakanishi R, Iimori M, Fujinaka Y, Tuul M, Yamashita N, Takata M, Kakeji Y, Maehara Y
- Organizer
  8^<th> Joint Conference of the AACR and JCA
- Place of Presentation
  ハワイ
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] A novel role of FancJ in the cellular response to 5-FU-induced DNA damages2010
- Author(s)
  Kitao H, Iimori M, Fujinaka Y, Kubo N, Nakanishi R, Munkhbold T, Yoshinaga K, Tokunaga E, Saeki H, Morita M, Kakeji Y, Takata M, Maehara Y.
- Organizer
  8^<th> AACR/JCA Conference
- Place of Presentation
  Hilton Waikoloa Village, Waikoloa, Hawaii, USA
- Year and Date
  2010-02-09
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] Possible contribution of FancJ in the repair process of 5-FU-induced DNA damages2010
- Author(s)
  Kitao H, Iimori M, Fujinaka Y, Nakanishi R, Tuul M, Yamashita N, Kubo N, Kakeji Y, Takata M, Maehara Y.
- Organizer
  22^<nd> Fanconi Anemia Research Fund Annual Meeting
- Place of Presentation
  Minneapolis, MN
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] 5-FU感受性規定因子としてのファンコニ貧血経路とその分子機序の解明2009
- Author(s)
  北尾洋之、藤中良彦、飯森真人、ムンフボルド・トール、久保信英、吉永敬士、中西良太、掛地吉弘、福島正和、高田穣、前原喜彦
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] Genomic instability phenotypes induced by loss of FancJ/Brip1 function2009
- Author(s)
  Kitao H, Nanda I, Kakeji Y, Maehara Y, Takata M
- Organizer
  American Association for Cancer Research 100th Annual Meeting
- Place of Presentation
  Colorado Convention Center, Denver,CO
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] A novel role of the FA core complex in FANCI phosphorylation, an important switch in the FA pathway.2009
- Author(s)
  Minoru Takata, Junya Tomida, Tomoko Shigechi, Hiroyuki Kitao, Akiko Itaya, Masamichilshiai
- Organizer
  Twenty-first Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Baltimore, MA, USA
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] FancJ/Brip1ヘリカーゼ欠損により生じるゲノム不安定性症候群2008
- Author(s)
  北尾洋之
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] Role of FANCI protein and its phosphorylation for the Fanconi anemia pathway function2008
- Author(s)
  M. Takata, H. Kitao, A. kinomura, A. Smogorzewska, S. J. Elledge, M. Ishiai
- Organizer
  Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] ファンコニ貧血経路の活性化制御とFANCIタンパク質のリン酸化メカニズム2008
- Author(s)
  冨田純也、内田亜希子、北尾洋之、木下英司、内田恵美、小林昌彦、山本健一、小池透、石合正道、高田穣
- Organizer
  日本放射線影響学会第51回大会
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Symposium : "DNA repair network deficiency and carcinogenesis"2008
- Author(s)
  Ishiai M, Kitao H, Takata M.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市, 神戸
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Frequent Loss of the Immunogolobulin Heavy Chain Gene Occurs in FANCJ deficient DT40 Cell Line2008
- Author(s)
  H. Kitao, I. Nada, A. Kinomura, M. Takata
- Organizer
  Nineteenth Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] FancJ/Brip1ヘリカーゼ欠損により生じるゲノム不安定性表現型2008
- Author(s)
  北尾洋之、Indrajit Nanda、木野村愛子、山添光芳、Michael Schmid、武田俊一、吉永敬士、前原喜彦、高田穣
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] ユビキチン化とリン酸化によるファンコニ貧血経路の制御機構2008
- Author(s)
  石合正道、北尾洋之、高田穣
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway Symposium.2008
- Author(s)
  Ishiai M, Kitao H, Takata M
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] FANCI phosphorylation functions as a-molecular switch toturn on the Fanconi anemia pathway. Symposium2008
- Author(s)
  Ishiai M, Kitao H, Takata M
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] Takata M. Frequent loss of the Immunoglobulin heavy chain gene occurs in FANCJ-deficient DT40 cell line2008
- Author(s)
  Kitao H, Nanda I, Kinomura A, Schmid M, Takata M
- Organizer
  Ataxia-Telangiectasia Workshop 2008
- Place of Presentation
  大津プリンスホテル
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] ファンコニ貧血経路の制御とFANCI タンパク質のリン酸化メカニズム2008
- Author(s)
  冨田純也、内田亜希子、北尾洋之、木下英司、内田恵美、小林昌彦、山本健一、小池透、石合正道、高田穣
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] BRCmotif-RPA融合蛋白はBRCA2欠損細胞の相同組換え修復異常を相補する2008
- Author(s)
  佐伯浩司、北尾洋之、江見泰徳、森田勝、掛地吉弘、前原喜彦、Maria Jasin
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. Symposium "DNA repair network deficiency and carcinogenesis".2008
- Author(s)
  Ishiai M., Kitao H., Takata M.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-17013083
[Presentation] ファンコニ貧血コア複合体によるモノユビキチン化とDNAクロスリンク修復制御2007
- Author(s)
  高田穣、北尾洋之、木野村愛子、石合正道
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] FancJ/BRIP1 helicasedeficient cells display huge loss of rearranged IgH locus2007
- Author(s)
  Kitao H, Kinomura A, Kimura M, Ishiai M, Takata M
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] Emergence of EGFR T790M mutation during chronic exposure to gefitinib in a non-small cell lung cancer cell line2007
- Author(s)
  Ogino A, Kitao H, Uchida A, Ishiai M, Takigawa N, Takata M, Kiura K, Tanimoto M
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] Role of FANCI protein and its pathway function2007
- Author(s)
  Takata M, Kitao H, Kinomura A, Smogorzewska A, Elledge SJ, Ishiai M
- Organizer
  19th Annual Fanconi Anemia Research
- Place of Presentation
  The Westin Michigan Avenue, Chicago, IL.
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] Regulation of DNA crosslink repair through monoubiquitination mediated by the Fanconi anemia core complex2007
- Author(s)
  Takata M, Kitao H, Kinomura A, Ishiai M
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] Frequent loss of the Immunoglobulin Heavy Chain Gene Occurs in FANCJ-deficient DT40 cell line2007
- Author(s)
  Kitao H, Nanda I, Kinomura A, Schmid M, Takata M
- Organizer
  19th Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  The Westin Michigan Avenue, Chicago, IL.
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] ファンコニ貧血コア複合体によるFANCD2/FANCI複合体のモノユビキチン化と相同組換え修復。ワークショップ放射線DNA損傷修復機構研究の最前線2007
- Author(s)
  高田穣、北尾洋之、木野村愛子、石合正道
- Organizer
  放射線影響学会6第50回大会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Frequent loss of the immunoglobulin heavy chain geneoccurs in FANCJ-deficient DT40 cells2007
- Author(s)
  Hiroyuki Kitao
- Organizer
  19th Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  Chicago, MI
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-19790234
[Presentation] FANCJ 遺伝子欠損DT40細胞株で起こる免疫グロブリン重鎖遺伝子でのゲノム欠失2007
- Author(s)
  北尾洋之、ナンダインドラジット、木野村愛子、シュミットマイケル、高田穣
- Organizer
  ワークショップ第30回分子生物学会第80回日本生化学会合同大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19390087
[Presentation] Coexistence of LOH at BRCA1 and TP53 loci is associated with aggressive phenotype and poor prognosis in breast cancer
- Author(s)
  Eriko Tokunaga, Nami Yamashita, Kenji Taketani, Koji Ando, Yasue Kimura, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Masaru Morita, Yoshihiko Maehara
- Organizer
  日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 5-FU感受性規定因子としてのファンコニ貧血経路
- Author(s)
  北尾洋之、藤中良彦、久保信英、中ノ子智徳、茂地智子、吉永敬士、ムンフボルド・トール、佐伯浩司、徳永えり子、江見泰徳、森田勝、掛地吉弘、前原喜彦
- Organizer
  第13回日本がん分子標的治療学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] 消化器癌におけるDNA aneuploidyの意義
- Author(s)
  安藤　幸滋、沖　　英次、吉田　綾恵、北尾　洋之、飯森　真人、佐伯　浩司、中島雄一郎、今村　裕、大垣　吉平、前原　喜彦
- Organizer
  第25回日本消化器癌発生学会総会第8回国際消化器癌発生会議
- Place of Presentation
  福岡
- Year and Date
  2014-11-13 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] 食道癌におけるLINE-1メチル化の生物学的意義および染色体不安定性に対する検討
- Author(s)
  河野　浩幸、北尾　洋之、大津　　甫、安藤　幸滋、日吉　幸晴、伊藤　修平、佐伯　浩司、沖　英次、森田　勝、前原　喜彦
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] 食道癌におけるグローバルDNA低メチル化と染色体不安定性
- Author(s)
  佐伯　浩司、河野　浩幸、西村　章、堤　亮介、中司　悠、工藤　健介、堤　智崇、由茅　隆文、田尻　裕匡、笠木　勇太、津田　康雄、財津　瑛子、安藤　幸滋、中島雄一郎、今村　裕、大垣　吉平、沖　英次、北尾　洋之、前原　喜彦
- Organizer
  第25回日本消化器癌発生学会総会第8回国際消化器癌発生会議
- Place of Presentation
  福岡
- Year and Date
  2014-11-13 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] Cellular response to a fluorinated thymidine analogue trifluridine, a key component of the novel oral antitumor drug TAS-102.
- Author(s)
  Hiroyuki Kitao
- Organizer
  Gordon Research Conference
- Place of Presentation
  Rockport, RI
- Year and Date
  2015-06-28 – 2015-07-03
- Data Source
  KAKENHI-PROJECT-25460390
[Presentation] Global DNA hypomethylation-mediated chromosomal instability is related to the initiation and progression of esophageal squamous cell carcinoma
- Author(s)
  Kawano H., Saeki H., Kitao H., Tsuda Y., Otsu H., Ando K., Ito S., Egashira A., Oki E., Morita M., Maehara Y.
- Organizer
  ASCO 2014 Annual meeting
- Place of Presentation
  Chicago
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] Global DNA hypomethylation-mediated chromosomal instability is related to the initiation and progression of esophageal squamous cell carcinoma
- Author(s)
  Kawano H, Saeki H, Kitao H, Tsuda Y, Otsu H, Ando K, Ito S, Egashira A, Oki E, Morita M, Maehara Y
- Organizer
  2014 Annual meeting of American Society of Clinical Oncology (ASCO)
- Place of Presentation
  Chicago
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-25462024
[Presentation] Trifluridine induces p53-dependent sustained G2 phase arrest with its massive misincorporation into DNA and few DNA strand breaks
- Author(s)
  Matsuoka K, Kitao H, 他
- Organizer
  American Association of Cancer Research (AACR) Annual Meeting 2015
- Place of Presentation
  Philadelphia, PA
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] 食道癌におけるグローバルDNA低メチル化と染色体不安定性
- Author(s)
  佐伯浩司、河野浩幸、西村　章、堤　亮介、中司　悠、工藤健介、堤　智崇、由茅隆文、田尻裕匡、笠木勇太、津田康雄、財津瑛子、安藤幸滋、中島雄一郎、今村　裕、大垣吉平、沖　英次、北尾洋之、前原喜彦
- Organizer
  第25回日本消化器癌発生学会総会/第8回国際消化器癌発生会議, シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2014-11-13 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-25462024

1. OKI Eiji (70380392)

# of Collaborated Projects: 13 results

# of Collaborated Products: 47 results
2. SAEKI Hiroshi (80325448)

# of Collaborated Projects: 11 results

# of Collaborated Products: 43 results
3. IIMORI Makoto (20546460)

# of Collaborated Projects: 9 results

# of Collaborated Products: 39 results
4. MORITA Masaru (30294937)

# of Collaborated Projects: 8 results

# of Collaborated Products: 36 results
5. TAKATA Minoru (30281728)

# of Collaborated Projects: 5 results

# of Collaborated Products: 33 results
6. TOKUNAGA Eriko (50325453)

# of Collaborated Projects: 4 results

# of Collaborated Products: 32 results
7. KAKEJI Yoshihiro (80284488)

# of Collaborated Projects: 4 results

# of Collaborated Products: 47 results
8. MATSUSHITA Nobuko (30333222)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
9. HIRANO Seiki (20368616)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
10. MAEHARA Yoshihiko (80165662)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
11. IKEDA Tetsuo (60585701)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. 安藤幸滋 (20608864)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
13. 岡野慎士 (10380429)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
14. 中島雄一郎 (40733564)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
15. ISHIAI Masamichi (90298844)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
16. TOMIDA Junya (50511367)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
17. 山下奈真 (60608967)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
18. 杉山雅彦 (40751079)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
19. AKIYOSHI Sayuri (50567360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
20. KOHNOE Shunji (30215199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
21. TSUJITANI Shunichi (30188544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
22. OHGA Takefumi (60335958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
23. EGASHIRA Akinori (00419524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SONODA Hideto (00465725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Emi Yasunori (50223673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. Ito Shuhei (10706914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. KIURA Katsuyuki (10243502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 山本和彦 (40333223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 播本憲史 (00419582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 古山正 (00419590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 原田結 (00608507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 間野洋平 (10792244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 馬場秀夫 (20240905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 赤星朋比古 (20336019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 松本拓也 (20374168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 副島雄二 (30325526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 森崎浩一 (30625801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 豊川剛二 (30627261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 吉野一郎 (40281547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 米満吉和 (40315065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 本村貴志 (50719507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 調憲 (70264025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 相島慎一 (70346774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 武冨紹信 (70363364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 内山秀昭 (70380425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 吉住朋晴 (80363373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 原田昇 (80419580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. 池上徹 (80432938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 岡本龍郎 (80568626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 木村光一 (80755273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 伊藤心二 (90382423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. 田川哲三 (90419557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. 庄司文裕 (90444851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. 中西良太 (90771254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
55. 工藤健介 (90801663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
56. 堤亮介 (60846541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
57. 橋本直隆 (30608964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. 久保信英 (20811748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
59. 諸富洋介 (60645365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
60. 安田光宏 (90269043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
61. 釣本敏樹 (30163885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
62. 三浦大典 (40532627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
63. 野中謙太朗 (90971713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
64. 佐藤太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
65. 胡桃坂仁志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
66. 中西真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KITAO HIROYUKI 北尾 洋之

KITAO Hiroyuki 北尾 洋之

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The critical role of ATR activation in the process of therapy-induced senescencePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNA involvement in the process of chemotherapy-induced DNA replication stressPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of therapy-induced senescence caused by replicative stressPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel molecular targeting strategy against chromosomal maintenance factor FANCJPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

KITAO HIROYUKI 北尾洋之

KITAO Hiroyuki 北尾洋之