Nito Chikako 仁藤智香子

… Alternative Names

永田智香子(仁藤智香子) ナガタチカコ

NAGATA Chikako 永田智香子

NITO Chikako 仁藤智香子

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Researcher Number	30409172
Other IDs
Affiliation (Current)	2023: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 日本医科大学, 医学部, 教授 2016 – 2020: 日本医科大学, 医学部, 准教授 2015: 日本医科大学, 医学部, 講師 2011 – 2012: 日本医科大学, 医学部, 講師 2010: 日本医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurology / Neurosurgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 90120:Biomaterials-related
Keywords	Principal Investigator 脳虚血 / 脳梗塞 / 局所脳虚血 / 血液脳関門障害 / 血管新生 / 歯髄幹細胞 / 遺伝子治療 / 幹細胞移植 / 局所脳虚血モデル / 肝細胞増殖因子 … More / Cdk5 / 神経細胞死 / アデノ随伴ウィルスベクター / 幹細胞治療 / AAVベクター / 脳保護効果 / 歯髄由来間葉系幹細胞 / 炎症抑制 / 脳虚血モデル / アデノ随伴ウイルスベクター / 血液脳関門 / 神経細胞保護 / 間葉系幹細胞 / 細胞治療 / エクソソーム … More Except Principal Investigator 幹細胞 / 細胞治療 / 脳出血 / ヒストン脱アセチル化酵素阻害剤 / 歯髄幹細胞 / 再生 / 神経保護 / 脳卒中 / 歯髄由来幹細胞 / 脳内出血 / 頭部外傷 / 神経再生医療 / 神経栄養因子 / 脳梗塞 / 肺炎 / 免疫調整 / トランスレーショナルリサーチ / 感染 / 核酸医薬 / ヘテロ核酸 / 臓器特異的 (脳・骨格筋) / 神経・筋疾患 / 臓器特異的 / 血管性認知症 / ドラッグリポジショニング / ケモカイン / 間葉系幹細胞 / iPS細胞 / ウイルス様粒子 / ゲノム編集治療 Less

改変iPS細胞由来間葉系幹細胞を用いた標的化ゲノム編集遺伝子治療法の開発
- Principal Investigator
  
  山崎吉之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Nippon Medical School
Development of innovative target organ-specific oligonucleotide therapy
- Principal Investigator
  
  永田哲也
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Tokyo Medical and Dental University
ケモカイン受容体デュアル制御分子に着目した血管性認知症に対する疾患修飾薬の確立
- Principal Investigator
  
  須田智
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
羊膜間葉系幹細胞由来エクソソームを利用した次世代型脳梗塞治療法の確立Principal Investigator
- Principal Investigator
  
  仁藤智香子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
重症頭部外傷に対する新規神経栄養因子を用いた再生治療の効率化
- Principal Investigator
  
  佐々木和馬
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
脳虚血後肺炎に対する歯髄由来幹細胞治療：肺内免疫に注目し、治療応用の可能性を探る
- Principal Investigator
  
  須田智
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
Therapeutic gene transfer enhances neuroprotective effects of dental pulp stem cells following focal cerebral ischemia ~ for clinical application ~Principal Investigator
- Principal Investigator
  
  Chikako Nito
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nippon Medical School
Combination therapy with dental pulp stem cells and histone deacetylase inhibitor against intracerebral hemorrhage in rat
- Principal Investigator
  
  SUDA SATOSHI
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Nippon Medical School
Effect of Dental Pulp Stem Cells Overexpressing Therapeutic Gene in a Rat Stroke Model.Principal Investigator
- Principal Investigator
  
  Nito Chikako
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Nippon Medical School
The role of CDK5 activation in neuronal death and angiogenesis after ischemic strokePrincipal Investigator
- Principal Investigator
  
  NAGATA Chikako (NITO Chikako)
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nippon Medical School

All 2022 2020 2019 2018 2017 2016 2012 2011 2010

All Journal Article Presentation Book

[Book] Therapeutic Windowを広げる時間を止める:t-PAと脳保護薬の併用の可能性.分子脳血管病第10巻第1号2010
- Author(s)
  仁藤智香子、片山泰朗
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-22590942
[Journal Article] Dental-Pulp Stem Cells as a Therapeutic Strategy for Ischemic Stroke2022
- Author(s)
  Nito Chikako、Suda Satoshi、Nitahara-Kasahara Yuko、Okada Takashi、Kimura Kazumi
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 4 Pages: 737-737
- DOI
  10.3390/biomedicines10040737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08981, KAKENHI-PROJECT-20H03788, KAKENHI-PROJECT-19K09492
[Journal Article] Recent Advances in Cell-Based Therapies for Ischemic Stroke2020
- Author(s)
  Satoshi Suda, Chikako Nito, Shoji Yokobori, Yuki Sakamoto, Masataka Nakajima, Kota Sowa, Hirofumi Obinata, Kazuma Sasaki, Sean I Savitz, Kazumi Kimura
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 18 Pages: 6718-6718
- DOI
  10.3390/ijms21186718
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09492
[Journal Article] Impact of Dental Pulp Stem Cells Overexpressing Hepatocyte Growth Factor after Cerebral Ischemia/Reperfusion in Rats2018
- Author(s)
  Sowa K, Nito C, Nakajima M, Suda S, Nishiyama Y, Sakamoto Y, Nitahara-Kasahara Y, Nakamura-Takahashi A, Ueda M, Kimura K, Okada T
- Journal Title
  
  Mol Ther Methods Clin Dev
  
  Volume: 10 Pages: 281-290
- DOI
  10.1016/j.omtm.2018.07.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10742, KAKENHI-PROJECT-15K10317, KAKENHI-PROJECT-26293328
[Journal Article] Transplantation of human dental pulp stem cells ameliorates brain damage following acute cerebral ischemia2018
- Author(s)
  Nito C, Sowa K, Nakajima M, Sakamoto Y, Suda S, Nishiyama Y, Nakamura-Takahashi A, Nitahara-Kasahara Y, Ueda M, Okada T, Kimura K
- Journal Title
  
  Biomed Pharmacother
  
  Volume: 108 Pages: 1005-1014
- DOI
  10.1016/j.biopha.2018.09.084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10742, KAKENHI-PROJECT-26293328
[Journal Article] Involvement of Mitogen-Activated Protein Kinase Pathways in Expression of the Water Channel Protein Aquaporin-4 after Ischemia in Rat Cortical Astrocytes2012
- Author(s)
  Nito C, Kamada H, Endo H, NarasimhanP, Lee Y-S, Chan PH
- Journal Title
  
  J Neurotrauma
  
  Volume: 29 Pages: 2404-12
- Data Source
  KAKENHI-PROJECT-22590942
[Journal Article] Neuroprotective Effect of an Antioxidant in Ischemic Stroke : Involvement of Neuronal Death Signaling and Blood-brain Barrier Disruption2011
- Author(s)
  Chikako Nito
- Journal Title
  
  J Nippon Med Sch.
  
  Volume: 78 Pages: 60-62
- NAID
  130004147093
- Data Source
  KAKENHI-PROJECT-22590942
[Journal Article] FK506 ameliorates oxidative damage and protects rat brain following transient focal cerebral ischemia2011
- Author(s)
  Nito C, Ueda M, Inaba T, Katsura K, Katayama Y
- Journal Title
  
  Neurol Res
  
  Volume: 33 Pages: 881-9
- Data Source
  KAKENHI-PROJECT-22590942
[Journal Article] FK506 ameliorates oxidative damage and protects rat brain following transient focal cerebral ischemia2011
- Author(s)
  Chikako Nito
- Journal Title
  
  Neurological Research
  
  Volume: 33 Pages: 881-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590942
[Journal Article] Neuroprotective Effect of an Antioxidant in Ischemic Stroke: Involvement of Neuronal Death Signaling and Blood-brain Barrier Disruption2011
- Author(s)
  Nito C, Katayama Y
- Journal Title
  
  J Nippon Med Sch
  
  Volume: 78 Pages: 60-62
- NAID
  130004147093
- Data Source
  KAKENHI-PROJECT-22590942
[Presentation] 時間で追う脳虚血の病態と治療:(3)慢性期　虚血性脳卒中における歯髄幹細胞をはじめとした細胞治療の展望2019
- Author(s)
  仁藤智香子
- Organizer
  日本脳循環代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10742
[Presentation] 歯髄幹細胞移植による新規脳梗塞治療の開発2019
- Author(s)
  仁藤智香子
- Organizer
  第44回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10742
[Presentation] Neuroprotective effects of human dental pulp stem cells after acute cerebral ischemia.2019
- Author(s)
  Nito C, Suda S, Sowa K, Nakajima M, Sakamoto Y, Takahashi S, Nishiyama Y, Kasahara YN, Okada T, Kimura K.
- Organizer
  The 25th Internal Symposium on Cerebral Blood Flow, Metabolism, and Function
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08981
[Presentation] 脳卒中におけるトランスレーショナル・リサーチ　歯髄由来幹細胞(DPSC)による虚血性脳卒中の治療法開発2019
- Author(s)
  仁藤智香子
- Organizer
  神経治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10742
[Presentation] Transplantation of human dental pulp stem cells attenuates brain injury after transient middle cerebral artery occlusion.2019
- Author(s)
  Nito C, Sowa K, Sakamoto Y, Takahashi S, Arakawa M, Suda S, Nishiyama Y, Takahashi A N, Kasahara YN, Kimura K, Okada T.
- Organizer
  第25回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08981
[Presentation] Effect of dental pulp stem cell overexpressing hepatocyte growth factor by AAV receptor in a rat stroke model.2018
- Author(s)
  Kota Sowa, Chikako Nito, Masataka Nakajima, Satoshi Suda, Yasuhiro Nishiyama,Aki- Nakamura Takahashi, Yuko Nitahara-Kasahara, Kiwamu Imagawa, Tohru Hirato, Masayuki Ueda, Kazumi Kimura, Takashi Okada
- Organizer
  The 24th Annual Meeting Japan Society of Gene and Cell Therapy
- Data Source
  KAKENHI-PROJECT-15K10317
[Presentation] Therapeutic Effect of Human Dental Pulp Stem Cells Overexpressing Hepatocyte Growth Factor in Experimental Stroke2018
- Author(s)
  Kota Sowa, Chikako Nito, Masataka Nakajima, Satoshi Suda, Yasuhiro Nishiyama, Aki Takahashi, Yuko Kasahara, Kiwamu Imagawa, Tohru Hirato, Masayuki Ueda, Takashi Okada, Kazumi Kimura
- Organizer
  International Stroke Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10317
[Presentation] Transplantation of dental pulp stem cells ameliorates brain damage after focal cerebral ischemia2017
- Author(s)
  仁藤智香子
- Organizer
  第57回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10742
[Presentation] ラット局所脳虚血モデルにおけるHGF強発現歯髄幹細胞移植の神経保護効果2017
- Author(s)
  岨康太，仁藤智香子, 中島壯崇, 須田智, 上田雅之, 笠原優子, 今川究, 平戸徹，岡田尚巳, 木村和美
- Organizer
  第42回日本脳卒中学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K10742
[Presentation] 虚血再灌流障害における歯髄幹細胞移植の神経保護効果2016
- Author(s)
  仁藤智香子、岨康太、中島壯崇、須田智、岡田尚巳、木村和美
- Organizer
  第59回　日本脳循環代謝学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-15K10317
[Presentation] ラット局所脳虚血モデルにおけるHGF強発現歯髄幹細胞移植の治療効果2016
- Author(s)
  岨康太、仁藤智香子、中島壯崇、須田智、岡田尚巳、木村和美
- Organizer
  第59回　日本脳循環代謝学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-15K10317
[Presentation] The neuroprotective effects of Post-treatment with atorvastatin reduces inflammatory responses and protects rat brain after transient focal ischemia2012
- Author(s)
  Saito T, Nito C, Ueda M, Inaba T, Kamiya F, Katayama Y
- Organizer
  42nd Annual Meeting of Society for Neuroscience
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-22590942
[Presentation] Neuroprotective effects of nicergoline against brain damage in a rat model of permanent focal cerebral ischemia2012
- Author(s)
  Nito C, Inaba T, Ueda M, Saito T, Katayama Y
- Organizer
  42nd Annual Meeting of Society for Neuroscience
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-22590942
[Presentation] Combination therapy with edaravone and mild hypothermia prevents MMP-9activiation and neurovascular injury after focal cerebral ischemia in rats2011
- Author(s)
  Nito C, Ueda M, Inaba T, Okubo S, Nomur K, Kamiya F, Ohta S, Katayama Y
- Organizer
  The 25th Internal Symposium on Cerebral Blood Flow, Metabolism, and Function
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22590942
[Presentation] Combination therapy with edaravone and mild hypothermia prevents MMP-9 activiation and neurovascular injury after focal cerebral ischemia in rats2011
- Author(s)
  Chikako Nito
- Organizer
  The 25th Internal Symposium on Cerebral Blood Flow, Metabolism, and Function
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-22590942
[Presentation] A free radical scavenger combined with mild hypothermia attenuates ischemic brain damage by suppressing matrix metalloproteinase 92011
- Author(s)
  Chikako Nito
- Organizer
  The 5th Korean-Japanese Joint Stroke Conference
- Place of Presentation
  Gyeongju, Korea
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22590942
[Presentation] A free radical scavenger and mild hypothemia for brain damage after focal ischemeia-Effects on MMP activation and blood-brain barrier disruption2010
- Author(s)
  Chikako Nito-Nagata
- Organizer
  The 1st Forum on Cerebral Blood Flow, Metabolism and Function Kyoto 2010
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-22590942
[Presentation] A free radical scavenger combined with mild hypothermia attenuates ischemic brain damage by suppressing matrix metalloproteinase 92010
- Author(s)
  Nito C, Ueda M, Inaba T, Nomura K, Katayama Y
- Organizer
  40th Annual Meeting of Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-22590942
[Presentation] A free radical scavenger combined with mild hypothermia ameriolates ischemic brain damage by suppressing matrix metalloproteinase 92010
- Author(s)
  Chikako Nito
- Organizer
  40th Annual Meeting of Neuroscience
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-22590942

1. SUDA SATOSHI (00366733)

# of Collaborated Projects: 7 results

# of Collaborated Products: 11 results
2. 横堀将司 (70449271)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 永田哲也 (50362976)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 宮川世志幸 (90415604)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 佐々木和馬 (30832266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山田真吏奈 (70508621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 阪本太吾 (90587073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 神尾孝一郎 (20465305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 原倫太朗 (70709766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 寺島裕也 (90538729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 笠原優子 (90391911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山崎吉之 (90407685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Okada Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. YOKOBORI Shouji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nito Chikako 仁藤 智香子

永田 智香子(仁藤智香子) ナガタ チカコ

NAGATA Chikako 永田 智香子

NITO Chikako 仁藤 智香子

Research Projects

Research Products

Co-Researchers

改変iPS細胞由来間葉系幹細胞を用いた標的化ゲノム編集遺伝子治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of innovative target organ-specific oligonucleotide therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ケモカイン受容体デュアル制御分子に着目した血管性認知症に対する疾患修飾薬の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

羊膜間葉系幹細胞由来エクソソームを利用した次世代型脳梗塞治療法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

重症頭部外傷に対する新規神経栄養因子を用いた再生治療の効率化

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳虚血後肺炎に対する歯髄由来幹細胞治療：肺内免疫に注目し、治療応用の可能性を探る

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic gene transfer enhances neuroprotective effects of dental pulp stem cells following focal cerebral ischemia ~ for clinical application ~Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Combination therapy with dental pulp stem cells and histone deacetylase inhibitor against intracerebral hemorrhage in rat

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of Dental Pulp Stem Cells Overexpressing Therapeutic Gene in a Rat Stroke Model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of CDK5 activation in neuronal death and angiogenesis after ischemic strokePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Therapeutic Windowを広げる時間を止める:t-PAと脳保護薬の併用の可能性.分子脳血管病第10巻第1号2010

Author(s)

Publisher

Data Source

[Journal Article] Dental-Pulp Stem Cells as a Therapeutic Strategy for Ischemic Stroke2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recent Advances in Cell-Based Therapies for Ischemic Stroke2020

Author(s)

Journal Title

DOI

Nito Chikako 仁藤智香子

永田智香子(仁藤智香子) ナガタチカコ

NAGATA Chikako 永田智香子

NITO Chikako 仁藤智香子

[Presentation] 時間で追う脳虚血の病態と治療:(3)慢性期　虚血性脳卒中における歯髄幹細胞をはじめとした細胞治療の展望2019

[Presentation] 脳卒中におけるトランスレーショナル・リサーチ　歯髄由来幹細胞(DPSC)による虚血性脳卒中の治療法開発2019