SHIMIZU Kosuke 清水広介

Researcher Number	30423841
Other IDs
Affiliation (Current)	2026: 浜松医科大学, 光医学総合研究所, 准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 浜松医科大学, 光医学総合研究所, 准教授 2016 – 2023: 浜松医科大学, 光尖端医学教育研究センター, 准教授 2016 – 2017: 浜松医科大学, 学内共同利用施設等, 准教授 2014 – 2016: 静岡県立大学, 薬学部, 講師 2006 – 2013: 静岡県立大学, 薬学部, 助教 2010: University of Shizuoka, 薬学部・大学院・薬学研究科, 助教
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90120:Biomaterials-related Except Principal Investigator Physical pharmacy / Medium-sized Section 21:Electrical and electronic engineering and related fields / Basic Section 53010:Gastroenterology-related / Basic Section 52040:Radiological sciences-related / Basic Section 21030:Measurement engineering-related / Basic Section 53030:Respiratory medicine-related … More / Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biomaterial science and engineering / General internal medicine and related fields / Medical pharmacy / Biological Sciences Less
Keywords	Principal Investigator リポソーム / ドラッグデリバリーシステム / DDS / PEG / 自己免疫疾患 / 自己抗原修飾リポソーム / 自己免疫疾患治療 / イメージング / がんイメージング / 逆標的化 … More / ターゲティング / がん / ビメンチン / がん治療 / 抗体 / 細胞表面ビメンチン / ナノ粒子 / 循環がん細胞 / PET / 抗PEG抗体 / ノイズキャンセリング / Chrna1 / アセチルコリン受容体 / アセチルコリン / 抗体アセチルコリン受容体抗体 / 筋電図 / EAMG / 筋電図測定 / 握力測定 / 実験的自己免疫性重症筋無力症（EAMG） / アセチルコリン受容体αサブユニット / 重症筋無力症 / 神経免疫疾患 / フィンゴリモド / 再発寛解型 / T細胞 / 標的化DDS / 抗原特異的T細胞 / 脾臓 / 実験的自己免疫性脳脊髄炎 / 多発性硬化症 / ホスファチジルセリン / カテプシンB / マクロファージ / アクチベータブル蛍光プローブ / 脾臓B細胞 / 根治療法 / 膵臓B細胞 / 胚中心 / Cry j 1 / B細胞 / スギ花粉症 / EPR効果 / リンパ管新生 / ドラッグデリバリー … More Except Principal Investigator リポソーム / DDS / 薬物送達システム / ドラッグデリバリー / 脳梗塞 / 薬物送達 / 虚血性疾患 / パルス磁場 / 磁性ナノ粒子 / アクティブターゲティング / ファスジル / ＤＤＳ / ナノ粒子 / アシアロエリスロポエチン / 細胞保護効果 / アレルギー / 逆標的化 / がん治療 / 磁化応答 / 血中循環がん細胞 / 膜小胞 / 光線力学療法 / 膵がん / リピドミクス / 放射線増感剤 / 神経膠芽腫 / X線直接励起型光増感剤 / がん温熱治療 / 磁気粒子イメージング / 腫瘍内環境 / 動的磁化計測 / 腫瘍内性状 / がん診断治療 / 磁気緩和 / ヘルパーT細胞 / 細胞傷害性T細胞 / ハイブリッド長鎖エピトープペプチド / 脂質ナノ粒子 / ハイブリッドエピトープ長鎖ペプチド / 能動輸送 / 脳内デリバリー / 高分子 / マイクロプラズマ / 散乱係数 / 生物・生体工学 / 生物物理 / 拡散光トモグラフィ / 脳組織 / 換算散乱係数 / 吸収係数 / 生体内光伝播 / ＭＭＰ / 脳出血抑制 / ＰＤＧＦ / 血栓溶解剤 / 治療可能時間 / 脳血管障害 / 脳血管疾患 / 組織プラスミノーゲン活性化因子 / 脳梗塞治療 / 動物 / SPECT / PET / 核医学 / ICG / 光イメージング / 線維化 / Tissue Factor / 蛍光イメージング / 肝星細胞 / Fab / 肝臓 / 抗体 / TissueFactor / NASH / 組織線維化 / 分子イメージング / 解毒 / 人工抗体 / 中和活性 / 毒素 / ポリマーリガンド / ポリマー粒子 / 膜流動性 / 毒素の中和 / ヒストン / 敗血症 / プラスチック抗体 / ノンインプリント人工抗体 / autoimmune disease / allergy / desensitization / liposome / drug delivery system / active targeting / reverse targeting / リボソーム / 自己免疫疾患 / 減感作 / 新生血管標的化 / ドキソルビシン / 併用療法 / 腫瘍血管新生 / miR-499 / miR499 / TEPA-PCL / 血管正常化 / マイクロRNA / ポリカチオンリポソーム / RNA干渉 / 核酸医薬品 / バイオパニング / ファージディスプレイペプチドライブラリー / 長期血中滞留性 / 薬学 / 行動薬理 / エリスロポエチン / タクロリムス / ＰＥＴ / 運動機能 / 脳保護薬 / 虚血再灌流障害 / 脳虚血再灌流障害 / ナノ粒 / タムスロシン / Cryjl / Cryj 1 / Cryj1 / ABC現象 / 免疫疾患 / 花粉症 / 血管新生 / 複標的化 / ターゲティング / 標的化 / 新生血管 Less

Development of a Treatment Method for Intractable Brain Tumors Using X-ray Direct Excitation Photodynamic Effect
- Principal Investigator
  
  荒牧修平
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hamamatsu University School of Medicine
Development of a new local treatment for pancreatic cancer by endoscopic PDT using liposomal DDS
- Principal Investigator
  
  山田貴教
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hamamatsu University School of Medicine
Non-invasive observation of tumor environment by magnetization response for cancer theranostics
- Principal Investigator
  
  大多哲史
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 21030:Measurement engineering-related
- Research Institution
  Shizuoka University
Basic research of noise-canceling technology for molecular imaging utilizing DDSPrincipal Investigator
- Principal Investigator
  
  清水広介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Hamamatsu University School of Medicine
Cancer theranostics developed by real-time detection of circulating tumor cells by magnetic vesicle
- Principal Investigator
  
  大多哲史
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 21:Electrical and electronic engineering and related fields
- Research Institution
  Shizuoka University
警告を受けた循環がん細胞を強制退場させるレフェリーナノ粒子の創製Principal Investigator
- Principal Investigator
  
  清水広介
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hamamatsu University School of Medicine
Creation of a microplasma device for active transport of macromolecular drugs to in vivo tissue
- Principal Investigator
  
  清水一男
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Shizuoka University
細胞内寄生菌に対するハイブリッド長鎖エピトープ搭載脂質ナノ粒子ワクチンの開発
- Principal Investigator
  
  榎本紀之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Hamamatsu University School of Medicine
Basic research for development of a new drug for the treatment of myasthenia gravisPrincipal Investigator
- Principal Investigator
  
  Shimizu Kosuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Hamamatsu University School of Medicine
Innovative DDS medicine for the complete recovery from autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  Shimizu Kosuke
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Hamamatsu University School of Medicine
Development of non-invasive imaging of tissue fibrosis
- Principal Investigator
  
  Magata Yasuhiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  General internal medicine and related fields
- Research Institution
  Hamamatsu University School of Medicine
Estimation of optical properties in biological tissue using time-resolved spectroscopy with femtosecond laser
- Principal Investigator
  
  Hoshi Yoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Hamamatsu University School of Medicine
Development of liposomal plastic antibody for novelDDS and applicaion for sepsis treatment
- Principal Investigator
  
  Oku Naoto
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Development of FA-Snap, a smart DDS drug, for proposing an innovative therapeutic modality of ischemic stroke.
- Principal Investigator
  
  OKU Naoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Teikyo University
  University of Shizuoka
Development of tumor-targetable, enzyme-specific activatable fluorescent probe for early diagnosis of tumorPrincipal Investigator
- Principal Investigator
  
  Shimizu Kosuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Hamamatsu University School of Medicine
  University of Shizuoka
Novel strategy of tumor treatiment via the normalization of tumor vasculature by microRNA
- Principal Investigator
  
  Oku Naoto
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Innovation of a novel technology for supporting the development of DDS drugs and protein medicines by controling their pharmacokinetics.
- Principal Investigator
  
  OKU NAOTO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Development of therapy for Japanese cedar pollinosis by utilizing reverse-targeting drug delivery systemPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Kosuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
New development of diagnostic and therapeutic modality for ischemia/reperfusion injury by intelligent DDS
- Principal Investigator
  
  OKU Naoto
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Development of novel nanoparticles for DDS, and establishment of Therapeutic modality for brain ischemia by use of these nanoparticles.
- Principal Investigator
  
  OKU Naoto
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
難治がんの克服を目標した発展型腫瘍新生血管標的化DDSに関する研究
- Principal Investigator
  
  OKU Naoto
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Shizuoka
A novel targeting DDS for the treatment of autoimmune diseases and allergy
- Principal Investigator
  
  OKU Naoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Influence of tumor lymphangiogenesis on tumor-targeting liposomal DDSPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Kosuke
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Development of Radical Treatment Modality for Curing Allergies and Immune Diseases by a Novel Consept, RTDDS
- Principal Investigator
  
  OKU Naoto
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Shizuoka

[Book] Brain Tumor Diagnosis Using PET with Angiogenic Vessel-Targeting Liposomes."Tumors of the Centra Nervous System volume3 Brain Tumors"(Part 1)2011
- Author(s)
  Kosuke Shimizu, Naoto Oku
- Publisher
  Springer London
- Data Source
  KAKENHI-PROJECT-22659010
[Book] Tumors of the Centra Nervous System volume3 Brain Tumors2011
- Author(s)
  K.Shimizu, N.Oku
- Total Pages
  8
- Publisher
  Springer London
- Data Source
  KAKENHI-PROJECT-22659010
[Book] 機能性DDSキャリアの製剤設計(岡田弘晃監修)2008
- Author(s)
  清水広介, ら
- Total Pages
  321
- Publisher
  むシーエムシー出版
- Data Source
  KAKENHI-PROJECT-20790041
[Book] 機能性DDSキャリアの製剤設計(岡田弘晃監修)2008
- Author(s)
  清水広介
- Publisher
  シーェムシー出版
- Data Source
  KAKENHI-PROJECT-20390014
[Journal Article] Enhancing Galantamine Distribution in Rat Brain Using Microplasma-Assisted Nose-to-Brain Drug Delivery2025
- Author(s)
  Sadiq Abubakar Hamza、Alam Md Jahangir、Begum Farhana、Hasan Mahedi、Kristof Jaroslav、Mamun Md. Al、Maniruzzaman Md.、Shimizu Kosuke、Kanazawa Takanori、Kahyo Tomoaki、Setou Mitsutoshi、Shimizu Kazuo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 26 Issue: 4 Pages: 1710-1710
- DOI
  10.3390/ijms26041710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K28433, KAKENHI-PROJECT-23K17473, KAKENHI-PROJECT-24K22407
[Journal Article] Measurement of magnetic relaxation in intratumor magnetic nanoparticles2025
- Author(s)
  Satoshi Ota, Hiroki Kosaka, Keita. Honda, Kota Hoshino, Haruki Goto, Masato Futagawa, Yasushi Takemura, Kosuke Shimizu
- Journal Title
  
  International Journal on Magnetic Particle Imaging
  
  Volume: 1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K26114
[Journal Article] The influence of barrier discharge by microplasma drug delivery system probe on cell viability and intracellular drug absorption2025
- Author(s)
  1.A. H. Sadiq, J. Kristof, A. M. Jahangir, S. A. Rimi, Y. Mizuno, T. Okada, K. Shimizu
- Journal Title
  
  Journal of Electrostatics
  
  Volume: 134 Pages: 104040-104040
- DOI
  10.1016/j.elstat.2025.104040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K17473
[Journal Article] Spiral Wire Microplasma Inducing Growth and Viability of Nasal Cell2024
- Author(s)
  2.A. H. Sadiq, J. Kristof, A. M. Jahangir, S. A. Rimi, Y. Mizuno, K. Shimizu
- Journal Title
  
  Recent Advances in Technology Research and Education, (Inter-Academia 2023)
  
  Volume: NA Pages: 164-173
- DOI
  10.1007/978-3-031-54450-7_18
- ISBN
  9783031544491, 9783031544507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K17473
[Journal Article] Characterization of Microscopic Structures in Living Tumor by In Vivo Measurement of Magnetic Relaxation Time Distribution of Intratumor Magnetic Nanoparticles2024
- Author(s)
  Ota Satoshi、Kosaka Hiroki、Honda Keita、Hoshino Kota、Goto Haruki、Futagawa Masato、Takemura Yasushi、Shimizu Kosuke
- Journal Title
  
  Advanced Materials
  
  Volume: 36 Issue: 46 Pages: 2404766-2404766
- DOI
  10.1002/adma.202404766
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H05652, KAKENHI-PROJECT-23K26114
[Journal Article] New strategy for MS treatment with autoantigen-modified liposomes and their therapeutic effect2021
- Author(s)
  Shimizu Kosuke、Agata Kazuki、Takasugi Shohei、Goto Shungo、Narita Yudai、Asai Tomohiro、Magata Yasuhiro、Oku Naoto
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 335 Pages: 389-397
- DOI
  10.1016/j.jconrel.2021.05.027
- NAID
  120007159864
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06593, KAKENHI-PROJECT-20K21905, KAKENHI-PROJECT-21H02614
[Journal Article] 免疫疾患治療のための新たなDDS創薬2021
- Author(s)
  清水広介
- Journal Title
  
  PHARM TECH JAPAN
  
  Volume: 37 Pages: 161-168
- NAID
  120007183696
- Data Source
  KAKENHI-PROJECT-21H02614
[Journal Article] 免疫疾患治療のための新たなDDS創薬2021
- Author(s)
  清水広介
- Journal Title
  
  PHARM TECH JAPAN
  
  Volume: 37 Pages: 161-168
- NAID
  120007183696
- Data Source
  KAKENHI-PROJECT-18K06593
[Journal Article] 多発性硬化症治療の現状とDDS創薬2020
- Author(s)
  清水広介
- Journal Title
  
  別冊BIO Clinica 慢性炎症と疾患　自己免疫疾患
  
  Volume: 9 Pages: 137-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06593
[Journal Article] Treatment of multiple sclerosis with DDS drug targeting to autoantigen-recognizing immune cells2020
- Author(s)
  清水広介
- Journal Title
  
  Drug Delivery System
  
  Volume: 35 Issue: 5 Pages: 367-375
- DOI
  10.2745/dds.35.367
- NAID
  130007991311
- ISSN
  0913-5006, 1881-2732
- Year and Date
  2020-11-25
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-18K06593
[Journal Article] In situ estimation of optical properties of rat and monkey brains using femtosecond time-resolved measurements.2019
- Author(s)
  Hoshi Y, Tanikawa Y, Okada E, Kawaguchi H, Shimizu K, Nemoto M, Kodama T, Watanabe M.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 9165-9165
- DOI
  10.1038/s41598-019-45736-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02081, KAKENHI-PROJECT-16K09732
[Journal Article] Macrophage-targeted, enzyme-triggered fluorescence switch-on system for detection of embolism-vulnerable atherosclerotic plaques.2019
- Author(s)
  Narita Y, Shimizu K, Ikemoto K, Uchino R, Kosugi M, Maess MB, Magata Y, Oku N, Ogawa M.
- Journal Title
  
  J. Control. Release
  
  Volume: 302 Pages: 105-115
- DOI
  10.1016/j.jconrel.2019.03.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05081, KAKENHI-PROJECT-15H02569
[Journal Article] Combination therapy with liposomal neuroprotectants and tissue plasminogen activator for treatment of ischemic stroke.2017
- Author(s)
  Fukuta T, Asai T, Yanagida Y, Namba M, Koide H, Shimizu K, Oku N.
- Journal Title
  
  The FASEB Journal
  
  Volume: 印刷中 Issue: 5 Pages: 1879-1890
- DOI
  10.1096/fj.201601209r
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02569, KAKENHI-PROJECT-14J10730, KAKENHI-PROJECT-16K08201, KAKENHI-PROJECT-16H05081
[Journal Article] Non-invasive evaluation of neuroprotective drug candidates for cerebral infarction by PET imaging of mitochondrial complex-1 activity2016
- Author(s)
  Tatsuya Fukuta, Tomohiro Asai, Takayuki Ishii, Hiroyuki Koide, Chiaki Kiyokawa, Masahiro Hashimoto, Takashi Kikuchi, Kosuke Shimizu, Norihiro Harada, Hideo Tsukada, Naoto Oku
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 30127-30127
- DOI
  10.1038/srep30127
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02569, KAKENHI-PROJECT-14J10730, KAKENHI-PROJECT-16K08201, KAKENHI-PROJECT-16H05081
[Journal Article] Neuroprotection against cerebral ischemia/reperfusion injury by intravenous administration of liposomal fasudil2016
- Author(s)
  Fukuta T, Asai T, Sato A, Namba M, Yanagida Y, Kikuchi T, Koide H, Shimizu K, Oku N.
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 506 Issue: 1-2 Pages: 129-137
- DOI
  10.1016/j.ijpharm.2016.04.046
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J10730, KAKENHI-PROJECT-25460041, KAKENHI-PROJECT-15H02569, KAKENHI-PROJECT-16H05081
[Journal Article] Challenge to the development of diagnostic and therapeutic drugs using liposomal drug delivery systems：8<sup>th</sup> Young Scientist Award, Japan Society of DDS2016
- Author(s)
  清水広介
- Journal Title
  
  Drug Delivery System
  
  Volume: 31 Issue: 4 Pages: 352-360
- DOI
  10.2745/dds.31.352
- NAID
  130006846570
- ISSN
  0913-5006, 1881-2732
- Language
  Japanese
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07896
[Journal Article] Neuroprotective effect of nobiletin on cerebral ischemia-reperfusion injury in transient middle cerebral artery-occluded rats.2014
- Author(s)
  Yasuda N, Ishii T, Oyama D, Fukuta T, Agato Y, Sato A, Shimizu K, Asai T, Asakawa T, Kan T, Yamada S, Ohizumi Y, Oku N.
- Journal Title
  
  Brain Res.
  
  Volume: 1559 Pages: 46-54
- DOI
  10.1016/j.brainres.2014.02.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23249005, KAKENHI-PROJECT-25460041, KAKENHI-PUBLICLY-26102736
[Journal Article] Real-time trafficking of PEGylated liposomes in the rodent focal brain ischemia analyzed by positron emission tomography2014
- Author(s)
  Fukuta T, Ishii T, Asai T, Nakamura G, Takeuchi Y, Sato A, Agato Y, Shimizu K, Asai S, Fukumoto D, Harada N, Tsukada H, Kawaguchi AT, Oku N
- Journal Title
  
  Artificial organs
  
  Volume: 38 Issue: 8 Pages: 662-6
- DOI
  10.1111/aor.12350
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J10730, KAKENHI-PROJECT-23249005, KAKENHI-PROJECT-24659049, KAKENHI-PROJECT-25460041, KAKENHI-PROJECT-25461167
[Journal Article] Biomembrane damage caused by exposure to multi-walled carbon nanotubes2013
- Author(s)
  Kosuke Shimizu, Arina Uchiyama, Mina Yamashita, Akihiko Hirose, Tetsuji Nishimura, Naoto Oku
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 38 Issue: 1 Pages: 7-12
- DOI
  10.2131/jts.38.7
- NAID
  10031138722
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790047
[Journal Article] Enhanced active targeting via cooperative binding of ligands on liposomes to target receptors.2013
- Author(s)
  Sugiyama T, Asai T, Nedachi YM, Katanasaka Y, Shimizu K, Maeda N, Oku N.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 6 Pages: e67550-e67550
- DOI
  10.1371/journal.pone.0067550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659021, KAKENHI-PROJECT-25460041
[Journal Article] Suppression of immune response by antigen-modified liposomes encapsulating model agents : A novel strategy for the treatment of allergy2013
- Author(s)
  Ichikawa K, Asai T, Shimizu K, Yonezavva S, Urakami T, Miyauchi H, Kawashima H, Ishida T, Kiwada H, and Oku N
- Journal Title
  
  J. Control. Release
  
  Volume: Vol. 167 Issue: 3 Pages: 284-289
- DOI
  10.1016/j.jconrel.2013.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390018, KAKENHI-PROJECT-24790047, KAKENHI-PROJECT-25460041
[Journal Article] Treatment of cerebral ischemia-reperfusion injury with PEGylated liposomes encapsulating FK506.2013
- Author(s)
  Ishii T, Asai T, Oyama D, Agato Y, Yasuda N, Fukuta T, Shimizu K, Minamino T, Oku N.
- Journal Title
  
  FASEB J.
  
  Volume: 27 Issue: 4 Pages: 1362-1370
- DOI
  10.1096/fj.12-221325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249005, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24790047, KAKENHI-PROJECT-25460041
[Journal Article] Enhanced active targeting via cooperative binding of ligands on liposomes to target receptors2013
- Author(s)
  Sugiyama T, Asai T, Nedachi YM, Katanasaka Y, Shimizu K, Maeda N, Oku N
- Journal Title
  
  PLoS One
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-24659021
[Journal Article] DDSの理想を追いかけて2013
- Author(s)
  清水広介
- Journal Title
  
  薬剤学
  
  Volume: 73 Pages: 171-175
- NAID
  10031171114
- Data Source
  KAKENHI-PROJECT-24790047
[Journal Article] Systemic delivery of small interfering RNA by use of targeted polycation liposomes for cancer therapy.2013
- Author(s)
  Kenjo E, Asai T, Yonenaga N, Ando H, Ishii T, Hatanaka K, Shimizu K, Urita Y, Dewa T, Nango M, Tsukada H, Oku N.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 36 Pages: 287-291
- NAID
  130003361373
- Data Source
  KAKENHI-PROJECT-24659021
[Journal Article] Nanoparticles accumulate in ischemic core and penumbra region even when cerebral perfusion is reduced.2013
- Author(s)
  Ishii T, Fukuta T, Agato Y, Oyama D, Yasuda N, Shimizu K, Kawaguchi AT, Asai T, Oku N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 430 Issue: 4 Pages: 1201-1205
- DOI
  10.1016/j.bbrc.2012.12.080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249005, KAKENHI-PROJECT-24249086, KAKENHI-PROJECT-24790047, KAKENHI-PROJECT-25460041
[Journal Article] Development of miR-92a delivery system for antiangiogenesis-based cancer therapy.2013
- Author(s)
  H. Ando, A. Okamoto, M. Yokota, K. Shimizu, T. Asai, T. Dewa, N. Oku
- Journal Title
  
  J. Gene Med.
  
  Volume: 15 Issue: 1 Pages: 20-27
- DOI
  10.1002/jgm.2690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790045, KAKENHI-PROJECT-24790047, KAKENHI-PROJECT-25460041, KAKENHI-PUBLICLY-23107713
[Journal Article] Amelioration of cerebral ischemia-reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin2012
- Author(s)
  T.Ishii, T.Asai, D.Oyama, T.Fukuta, N.Yasuda, K.Shimizu, T.Minamino, N.Oku
- Journal Title
  
  Journal of Controlled Release
  
  Volume: (In press) Issue: 1 Pages: 81-87
- DOI
  10.1016/j.jconrel.2012.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J55523, KAKENHI-PROJECT-22790045, KAKENHI-PROJECT-23249005, KAKENHI-PROJECT-23659416, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24790047
[Journal Article] Inhibitory Effect of Liposomal Rhinacanthin-N Isolated from <i>Rhinacanthus nasutus</i> on Pulmonary Metastasis in Mice2012
- Author(s)
  Pongpun Siripong, Jantana Yahuafai, Suratsawadee Piyaviriyakul, Kwanjai Kanokmedhakul, Hiroyuki Koide, Takayuki Ishii, Kosuke Shimizu, Somsak Ruchirawat, Naoto Oku
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 7 Pages: 1197-1200
- DOI
  10.1248/bpb.b12-00244
- NAID
  130001872126
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790047
[Journal Article] RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment.2012
- Author(s)
  Yonenaga N, Kenjo E, Asai T,Tsuruta A, Shimizu K, Dewa T, Nango M, Oku N:
- Journal Title
  
  J. Control. Release
  
  Volume: 160 Issue: 2 Pages: 177-181
- DOI
  10.1016/j.jconrel.2011.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790045, KAKENHI-PROJECT-24790047, KAKENHI-PUBLICLY-23107713
[Journal Article] A single injection of liposomal asialo-erythropoietin improves motor function deficit caused by cerebral ischemia/reperfusion.2012
- Author(s)
  T. Ishii, T. Asai, T. Fukuta, D. Oyama, N. Yasuda, Y. Agato, K. Shimizu, T. Minamino, N. Oku
- Journal Title
  
  Int. J. Pharm.
  
  Volume: 439 Issue: 1-2 Pages: 269-274
- DOI
  10.1016/j.ijpharm.2012.09.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790045, KAKENHI-PROJECT-23249005, KAKENHI-PROJECT-24790047
[Journal Article] Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer.2012
- Author(s)
  K. Nishikawa, T. Asai, H. Shigematsu, K. Shimizu, H. Kato, Y. Asano, S. Takashima, E. Mekada, N. Oku, T. Minamino
- Journal Title
  
  J. Control. Release
  
  Volume: 160 Issue: 2 Pages: 274-280
- DOI
  10.1016/j.jconrel.2011.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790045, KAKENHI-PROJECT-22890104, KAKENHI-PROJECT-23240126, KAKENHI-PROJECT-23659416, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24790047
[Journal Article] Anti-angiogenic activity and intracellular distribution of epigallocatechin-3-gallate analogs.2011
- Author(s)
  Piyaviriyakul S, Shimizu K, Asakawa T, Kan T, Siripong P, Oku N.
- Journal Title
  
  Biol Pharm Bull. 34
  
  Pages: 396-400
- NAID
  130000657819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Preventive effect of green tea catechins on experimental tumor metastasis in senescence-accelerated mice.2010
- Author(s)
  Shimizu K, Kinouchi Shimizu N, Hakamata W, Unno K, Asai T, Oku N.
- Journal Title
  
  Biol.Pharm.Bull. 33
  
  Pages: 117-121
- NAID
  130000140203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Preventive effect of green tea catechins on experimental tumor metastasis in senescence-accelerated mice2010
- Author(s)
  Kosuke Shimizu, et al.
- Journal Title
  
  Biol.Pharm.Bull. 33
  
  Pages: 117-121
- NAID
  130000140203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Temperature-dependent transfer of amphotericin B from liposomal membrane of AmBisome to fungal cell membrane.2010
- Author(s)
  Shimizu K, Osada M, Takemoto K, Yamamoto Y, Asai T, Oku N.
- Journal Title
  
  J.Control.Release 141
  
  Pages: 208-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] PET imaging of brain cancer with positron emitter-labeled liposomes2010
- Author(s)
  Naoto Oku, Mina Yamashita, Yurie Katayama, Takeo Urakami, Kentaro Hatanaka, Kosuke Shimizu, Tomohiro Asai, Hideo Tsukada, Shuji Akai, Hiroaki Kanazawa
- Journal Title
  
  Int. J. Pharm
  
  Volume: 403 Pages: 170-177
- Data Source
  KAKENHI-PROJECT-22659010
[Journal Article] PET imaging of brain cancer with positron emitter-labeled liposomes.2010
- Author(s)
  Oku N, Yamashita M, Katayama Y, Urakami T, Hatanaka K, Shimizu K, Asai T, Tsukada H, Akai S, Kanazawa H.
- Journal Title
  
  Int J Pharm. 403
  
  Pages: 170-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] A novel DDS strategy, "dual-targeting", and its application for antineovascular therapy.2010
- Author(s)
  Murase Y, Asai T, Katanasaka Y, Sugiyama T, Shimizu K, Maeda N, Oku N.
- Journal Title
  
  Cancer Lett. 287
  
  Pages: 165-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Anti-obesity effect of phosphatidylinositol on diet-induced obesity in mice2010
- Author(s)
  Kosuke Shimizu, et al.
- Journal Title
  
  J.Agric.Food Chem.
  
  Volume: 58 Pages: 11218-11225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Temperature-dependent transfer of amphotericin B from liposomal membrane of AmBisome to fungal cell membrane2010
- Author(s)
  Kosuke Shimizu, et al.
- Journal Title
  
  J.Control.Release 141
  
  Pages: 208-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Anti-obesity effect of phosphatidylinositol on diet-induced obesity in mice.2010
- Author(s)
  Shimizu K, Ida T, Tsutsui H, Asai T, Otsubo K, Oku N.
- Journal Title
  
  J.Agric.Food Chem. 58
  
  Pages: 11218-11225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] PEG化ナノキャリア頻回投与によるaccelerated blood clearance現象の機構解明2009
- Author(s)
  小出裕之、浅井知浩、畑中剣太朗、清水広介、横山昌幸、石田竜弘、際田弘志、奥直人
- Journal Title
  
  YAKUGAKU ZASSHI 129
  
  Pages: 1445-1451
- NAID
  130000136135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390014
[Journal Article] In vivo distribution of liposome-encapsulated hemoglobin determined by positron emission tomography.2009
- Author(s)
  Urakami T, Kawaguchi AT, Akai S, Hatanaka K, Koide H, Shimizu K, Asai T, Fukumoto D, Harada N, Tsukada H, Oku N.
- Journal Title
  
  Artif.Organs 33
  
  Pages: 164-168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Enhanced experimental tumor metastasis with age in senescence-accelerated mouse.2008
- Author(s)
  Shimizu K, Kinouchi Shimizu N, Asai T, Tsukada H, Oku N.
- Journal Title
  
  Biol.Pharm.Bull. 31
  
  Pages: 847-851
- NAID
  110006663939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Antineovascular therapy with angiogenic vessel-targeted polyethyleneglycol-shielded liposomal DPP-CNDAC.2008
- Author(s)
  Asai T, Miyazawa S, Maeda N, Hatanaka K, Katanasaka Y, Shimizu K, Shuto S, Oku N.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 1029-1033
- NAID
  10024006453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Chronopharmacologic cancer treatment with and angiogenic vessel-targeted liposomal drug2008
- Author(s)
  Kosuke Shimizu, et.al.
- Journal Title
  
  Biol. Pharm. Bull 31
  
  Pages: 95-98
- NAID
  110006569981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Enhanced experimental tumor metastasis with age in senescence-accelerated mouse2008
- Author(s)
  Kosuke Shimizu, et.al.
- Journal Title
  
  Biol. Pharm 31
  
  Pages: 847-851
- NAID
  110006663939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Journal Article] Antiangiogenic cancer therapy using tumor vasculature-targeted liposomes encapsulating 3-(3,5-dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydro-in dol-2-one, SU5416.2008
- Author(s)
  Katanasaka Y, Ida T, Asai T, Shimizu K, Koizumi F, Maeda N, Baba K, Oku N.
- Journal Title
  
  Cancer Lett. 270
  
  Pages: 260-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790041
[Patent] 自己免疫疾患の治療又は予防剤2018
- Inventor(s)
  清水広介、奥直人
- Industrial Property Rights Holder
  清水広介、奥直人
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2019-031481
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] Measurement of magnetic relaxation in intratumor magnetic nanoparticles2025
- Author(s)
  Satoshi Ota, Hiroki Kosaka, Keita Honda, Kota Hoshino, Haruki Goto, Masato Futagawa, Yasushi Takemura, Kosuke Shimizu
- Organizer
  14th International Workshop on Magnetic Particle Imaging
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26114
[Presentation] Novel Technique of Microplasma Assisted Nose-to-Brain Drug Delivery2025
- Author(s)
  A. H. Sadiq, A. M. Jahangir, F. Begum, M. Hasan, T. Yamano, J. Kristof, K. Shimizu
- Organizer
  The 11th International Symposium toward the Future of Advanced Research at Shizuoka University
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17473
[Presentation] Dielectric Barrier Discharge Microplasma Assisted Nose-to-Brain drug delivery2024
- Author(s)
  H. A. Sadiq, A. M. Jahangir. J. Kristof, M. Hasan, F. Begum, K. Shimizu
- Organizer
  3rd International virtual Conference on Neuroscience, Brain Disorders & Therapeutics, Virtual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17473
[Presentation] Evaluation of in vivo magnetization dynamics of magnetic nanoparticles in living tumor2024
- Author(s)
  Satoshi Ota, Hiroki Kosaka, Keita Honda, Kota Hoshino, Haruki Goto, Masato Futagawa, Yasushi Takemura, Kosuke Shimizu
- Organizer
  14th International Conference on the Scientific and Clinical Applications of Magnetic Carriers
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K26114
[Presentation] 磁性ナノ粒子を活用した腫瘍組織性状の推定と空間分解能の検討2024
- Author(s)
  鈴木千博, 小坂宏輝, 二川雅登, 竹村泰司, 清水広介, 大多哲史
- Organizer
  マグネティックス/マイクロマシン・センサシステム/バイオ・マイクロシステム合同研究会
- Data Source
  KAKENHI-PROJECT-23K26114
[Presentation] Drug Delivery and Cell Membrane Response to Spiral DBD Plasma2024
- Author(s)
  A. H. Sadiq, F. Begum, A. M. Jahangir, M. Hasan, J. Kristof, K. Shimizu
- Organizer
  The 9th International Symposium on Biomedical Engineering (ISBE2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17473
[Presentation] 磁性ナノ粒子を用いた生体内腫瘍における磁化応答計測システムの高感度化の検討2024
- Author(s)
  小坂宏輝, 二川雅登, 竹村泰司, 清水広介, 大多哲史
- Organizer
  マグネティックス研究会
- Data Source
  KAKENHI-PROJECT-23K26114
[Presentation] Observation of OH radical generated in culture medium by spiral DBD microplasma2024
- Author(s)
  A. H. Sadiq, J. Kristof, A. M. Jahangir, M. Hasan, S. A. Rimi, K. Shimizu
- Organizer
  Future of Advanced Researches at Shizuoka University (ISFAR-SU2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17473
[Presentation] Active release of liposomal cytotoxic drug by irradiation of near-infrared light and its cancer therapeutic effect2024
- Author(s)
  Kosuke Shimizu, Yudai Narita, Yuri Katsurada, Yasunobu Matsumoto, Hiroshi Kikuchi, Naoto Oku, Kenji Hyodo
- Organizer
  Liposome Research Days Conference 2024 (LRD2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K03279
[Presentation] 標的化DDSが拓く新たな多発性硬化症治療創薬2024
- Author(s)
  清水広介
- Organizer
  第36回日本神経免疫学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-24K03279
[Presentation] 磁性ナノ粒子の磁気緩和機構解析による生体内腫瘍の性状評価2024
- Author(s)
  小坂宏輝, 本夛勁汰, 二川雅登, 竹村泰司, 清水広介, 大多哲史
- Organizer
  第48回日本磁気学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K26114
[Presentation] 免疫疾患を克服する新たな標的化DDS創薬2024
- Author(s)
  清水広介
- Organizer
  徳島大学大学院医歯薬学研究部DDS研究センターシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] 腫瘍内に投与された磁性ナノ粒子の磁化応答に基づく緩和時間解析2023
- Author(s)
  大多哲史, 小坂宏輝, 本夛勁汰, 二川雅登, 清水広介, 竹村泰司
- Organizer
  第32回MAGDAコンファレンス
- Data Source
  KAKENHI-PROJECT-23K26114
[Presentation] Wire microplasma inducing growth and viability of nasal cells2023
- Author(s)
  H. A. Sadiq, J. Kristof, A. M. Jahangir, S. A. Rimi, Y. Mizuno and K. Shimizu
- Organizer
  Inter-Academia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17473
[Presentation] Investigating the cellular barrier permeation using wire microplasma2023
- Author(s)
  A. H. Sadiq, J. Kristof, A. Jahangir, S. A. Rimi, Y. Mizuno, T. Okada, K. Shimizu
- Organizer
  2023 Annual Meeting of the Electrostatics Society of America (ESA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17473
[Presentation] 生体内腫瘍における磁性ナノ粒子の磁気緩和機構の評価2023
- Author(s)
  小坂宏輝, 本夛勁汰, 二川雅登, 清水広介, 竹村泰司, 大多哲史
- Organizer
  日本磁気学会第47回学術講演会
- Data Source
  KAKENHI-PROJECT-23K26114
[Presentation] マイクロプラズマ照射による細胞内への高分子DDSの検討2023
- Author(s)
  清水一男, アラム・ムハンマド・ジヤハンギル, 岡田　拓己, 大石恭平, アフリン・サディアリミ, アブバカ・ハムザ・サディク, クリストフ・ヤロスラヴ
- Organizer
  第39回日本DDS学会・学術集会
- Data Source
  KAKENHI-PROJECT-23K17473
[Presentation] A new strategy for multiple sclerosis treatment with autoantigen-modified liposomes2022
- Author(s)
  Kosuke Shimizu, Shohei Takasugi, Kazuki Agata, Yudai Narita, Tomohiro Asai,Yasuhiro Magata, Naoto Oku
- Organizer
  Liposome Research Days Conference 2022 (LRD2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] MS治療に向けた自己抗原修飾リポソーム製剤のEAE治療効果の検討2022
- Author(s)
  清水広介、高杉昇平、阿形寿規、成田雄大、奥直人、間賀田泰寛
- Organizer
  第34回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] 免疫疾患克服に向けた新たな標的化DDSの開発2022
- Author(s)
  清水広介
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2022
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] 自己抗原特異的免疫細胞への標的化DDSによる多発性硬化症治療2022
- Author(s)
  清水広介、高杉昇平、阿形寿規、間賀田泰寛、奥直人
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] 免疫疾患治療・根治に向けた標的化DDS創薬研究2022
- Author(s)
  清水広介
- Organizer
  日本薬剤学会第37年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] 免疫疾患治療のための新規製剤技術2021
- Author(s)
  清水広介
- Organizer
  BioJapan 2021
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 免疫疾患治療のための新たなDDS創薬研究2021
- Author(s)
  清水広介
- Organizer
  日本薬剤学会第36年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 鮮明なイメージング画像を得るためのDDSの利用と病態イメージング応用2021
- Author(s)
  清水広介
- Organizer
  日本薬剤学会第36年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] Neogenin遺伝子発現抑制による実験的自己免疫性脳脊髄炎治療2021
- Author(s)
  清水広介、間賀田泰寛
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] 免疫疾患治療のための新たなDDS創薬研究2021
- Author(s)
  清水広介
- Organizer
  日本薬剤学会第36年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] 鮮明なイメージング画像を得るためのDDSの利用と病態イメージング応用2021
- Author(s)
  清水広介
- Organizer
  日本薬剤学会第36年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] 免疫疾患治療のための新規製剤技術2021
- Author(s)
  清水広介
- Organizer
  BioJapan 2021
- Data Source
  KAKENHI-PROJECT-21H02614
[Presentation] Neogenin遺伝子発現抑制による実験的自己免疫性脳脊髄炎治療2021
- Author(s)
  清水広介、間賀田泰寛
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 自己抗原修飾リポソームによる自己抗原認識免疫細胞への標的化と自己免疫疾患治療2021
- Author(s)
  清水広介，高杉昇平，阿形寿規，成田雄大，浅井知浩，奥直人，間賀田泰寛
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 自己抗原認識免疫細胞を標的とする多発性硬化症治療薬の開発2020
- Author(s)
  清水広介，高杉昇平，阿形寿規，成田雄大，浅井知浩，奥直人，間賀田泰寛
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 多発性硬化症治療に向けた自己抗原修飾リポソーム製剤の開発2020
- Author(s)
  清水広介，高杉昇平，阿形寿規，成田雄大，浅井知浩，奥直人，間賀田泰寛
- Organizer
  第32回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 抗組織因子抗体を用いたNASHにおける肝組織線維化イメージング2020
- Author(s)
  清水広介、松村保広、間賀田泰寛
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K19650
[Presentation] 自己抗原修飾リポソームを用いた自己免疫疾患治療の機構解析2019
- Author(s)
  髙杉昇平、清水広介、阿形寿規、成田雄大、間賀田泰寛、奥直人、浅井知浩
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 自己抗原修飾リポソームを用いた実験的自己免疫性脳脊髄炎治療2019
- Author(s)
  髙杉昇平、清水広介、阿形寿規、成田雄大、奥直人、浅井知浩
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 自己抗原修飾リポソームを用いた標的化DDSによる自己免疫疾患治療2019
- Author(s)
  清水広介、高杉昇平、阿形寿規、成田雄大、浅井知浩、奥直人、間賀田泰寛
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 自己抗原認識免疫細胞への標的化DDSと多発性硬化症治療応用2019
- Author(s)
  清水広介、高杉昇平、阿形寿規、成田雄大、浅井知浩、奥直人、間賀田泰寛
- Organizer
  第31回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] Autoantigen-modified liposomes as an immune cell-targetable drug carrier for the treatment of multiple sclerosis2019
- Author(s)
  Shohei Takasugi, Kazuki Agata, Naoto Oku, Tomohiro Asai, Kosuke Shimizu
- Organizer
  Liposome Research Days 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] Development of autoantigen-modified liposomes for the treatment of autoimmune diseases2019
- Author(s)
  Shohei Takasugi, Kazuki Agata, Yudai Narita, Naoto Oku, Tomohiro Asai, Kosuke Shimizu
- Organizer
  CRS2019 Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 逆標的化DDS戦略を利用した自己免疫疾患治療2018
- Author(s)
  清水広介、阿形寿規、後藤峻吾、高杉昇平、成田雄大、奥直人
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] 自己免疫疾患治療を可能とする新たなDDS創薬2018
- Author(s)
  清水広介
- Organizer
  BIO tech 2018　第15回アカデミックフォーラム
- Data Source
  KAKENHI-PROJECT-18K06593
[Presentation] NIRF imaging of atherosclerotic plaques with fluorescence activatable probe and macrophage-targeting DDS2017
- Author(s)
  Yudai Narita, Kosuke Shimizu, Marten Maess, Kazuya Hokamura, Yasuhiro Magata, Mikako Ogawa, Naoto Oku
- Organizer
  2017 AAPS Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] 動脈硬化不安定プラークの近赤外蛍光イメージングを目的としたマクロファージ標的化リポソームの開発2017
- Author(s)
  成田雄大、清水広介、間賀田泰寛、外村和也、小川美香子、奥　直人
- Organizer
  第12回日本分子イメージング学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] マクロファージ標的化アクチベータブル蛍光プローブによる動脈硬化不安定プラークの近赤外蛍光イメージング2017
- Author(s)
  清水広介、成田雄大、Marten Maess、外村和也、間賀田泰寛、奥　直人、小川美香子
- Organizer
  第12回日本分子イメージング学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] 近赤外蛍光アクチベータブルプローブとマクロファージ標的化DDSによる動脈硬化不安定プラークイメージング2017
- Author(s)
  成田雄大、清水広介、間賀田泰寛、外村和也、小川美香子、奥　直人
- Organizer
  第81回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] 光スイッチプローブDDSを応用した新規動脈硬化診断法の開発2017
- Author(s)
  成田雄大、清水広介、間賀田泰寛、小川美香子、奥　直人
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] Usefulness of liposomal neuro-protectants for the treatment of ischemic stroke2017
- Author(s)
  Naoto Oku, Tatsuya Fukuta, Hiroyuki Koide, Kosuke Shimizu, Tomohiro Asai
- Organizer
  Liposome Advances Progress in Drug and Vaccine Delivery
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05081
[Presentation] マクロファージ標的化蛍光プローブによる動脈硬化不安定プラークの検出2017
- Author(s)
  清水広介、成田雄大、Marten Maess、外村和也、間賀田泰寛、奥　直人、小川美香子
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] Combination therapy with liposomal fasudil and tissue plasminogen activator for ischemic stroke treatment2017
- Author(s)
  Yosuke Yanagida, Tatsuya Fukuta, Tomohiro Asai, Kosuke Shimizu, Hiroyuki Koide, Naoto Oku:
- Organizer
  Liposomes Advances Progress in Drug and Vaccine Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05081
[Presentation] Development of enzyme-specific, macrophage-targeted near-infrared fluorescence probe for easy diagnosis of atherosclerosis2017
- Author(s)
  Kosuke Shimizu, Yudai Narita, Marten Maess, Yasuhiro Magata, Mikako Ogawa, Naoto Oku
- Organizer
  Controlled Release Society 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] Optical imaging for detecting atherosclerotic plaques by use of macrophage-targeted liposomes encapsulating activatable fluorescent probe2017
- Author(s)
  Kosuke Shimizu, Yudai Narita, Mikako Ogawa, Naoto Oku, Yasuhiro Magata
- Organizer
  第22回静岡健康・長寿学術フォーラム
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] NIRF imaging vulnerable atherosclerotic plaques with activatable probe-encapsulated liposomes2017
- Author(s)
  Yudai Narita, Kosuke Shimizu, Marten Maess, Kazuya Hokamura, Yasuhiro Magata, Mikako Ogawa, Naoto Oku
- Organizer
  ILS and LRD Combined Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] リポソームDDSの疾患診断・治療への応用2017
- Author(s)
  清水広介
- Organizer
  InnoPack Japanコンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] アクチベータブル蛍光プローブDDS製剤による動脈硬化宇安定プラークイメージング2017
- Author(s)
  成田雄大、清水広介、Maess Marten、間賀田泰寛、外村和也、小川美香子、奥　直人
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] リポソームDDSの魅力、疾患診断・治療へのチャレンジ2016
- Author(s)
  清水広介
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] 動脈硬化不安定プラーク近赤外蛍光イメージングを指向したマクロファージ標的化DDS製剤の開発2016
- Author(s)
  成田雄大、清水広介、小川美香子、Marten Maess、間賀田泰寛、奥直人
- Organizer
  日本分子イメージング学会第11回総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] Development of activatable fluorescence probe for easy diagnosis of cancer2015
- Author(s)
  Yudai Narita, Yoshihito Takeuchi, Keisuke Ikemoto, Kosuke Shimizu, Mikako Ogawa, Yasuhiro Magata, Naoto Oku
- Organizer
  42nd Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Edinburgh, Scotland
- Year and Date
  2015-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] リポソームDDSの応用による疾患イメージング研究2015
- Author(s)
  清水広介
- Organizer
  日本分析化学会中部支部静岡講演会
- Place of Presentation
  静岡
- Year and Date
  2015-09-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] がん特異的検出を目指した蛍光スイッチ機能を有するリポソームの開発2015
- Author(s)
  清水広介、成田雄大、橋本正寛、Marten Maess、小川美香子、間賀田泰寛、奥直人
- Organizer
  第10回日本分子イメージング学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] リポソームDDSを利用した疾患イメージング2015
- Author(s)
  清水広介
- Organizer
  第 15 回放射性医薬品・画像診断薬研究会
- Place of Presentation
  京都
- Year and Date
  2015-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-15K07896
[Presentation] 分子イメージングとDDS創薬2014
- Author(s)
  奥直人、清水広介、浅井知浩、菅敏幸、塚田秀夫
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] リポソームを用いた脳虚血部位への脳保護剤デリバリー2014
- Author(s)
  11.福田達也、浅井知浩、佐藤晶彦、清水広介、南野哲男、塚田秀雄、奥直人
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] RT-DDS: A novel targeting strategy for the treatment of allergy2014
- Author(s)
  Daiki Saito, Tomoki Yokoyama, Kota Matsuki, Ayumi Ito, Shungo Goto, Kosuke Shimizu, Tomohiro Asai, Naoto Oku
- Organizer
  Liposome Research Days 2014
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] NMDA受容体遮断薬内封リポソームを用いた脳虚血再灌流障害の治療2014
- Author(s)
  3.菊地隆司、上戸由里佳、福田達也、清水広介、浅井知浩、奥　直人
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] リポソームDDS製剤の虚血時投与による脳虚血/再灌流障害治療2014
- Author(s)
  1.福田達也、佐藤昌彦、菊地隆司、清水広介、浅井知浩、南野哲男、奥　直人
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮
- Year and Date
  2014-05-20
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Reverse targeting DDS for the treatment of immune diseases2014
- Author(s)
  Naoto Oku, Kosuke Shimizu, Tomoki Yokoyama, Kota Matsuki
- Organizer
  Liposome Research Days 2014
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] 抗原修飾リポソームにより脾臓B細胞を標的化した新たなスギ花粉治療療法の開発2014
- Author(s)
  後藤峻吾、松木孝太、伊藤あゆみ、斉藤大騎、橋本正寛、清水広介、浅井知浩、奥直人
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] 脳虚血時におけるリポソームの動態解析と脳梗塞治療への応用2014
- Author(s)
  2.福田達也、佐藤昌彦、菊地隆司、清水広介、浅井知浩、南野哲男、塚田秀夫、奥　直人
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] The design of a liposomal delivery system for the treatment of ischemic stroke.2014
- Author(s)
  5.Tomohiro Asai, Tatsuya Fukuta, Takayuki Ishii, Akihiko Sato, Takashi Kikuchi, Kosuke Shimizu, Hideo Tsukada, Naoto Oku
- Organizer
  Liposome Research Days 2014
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-08-06
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Delivery of neuroprotective agents to ischemic brain region using liposomes for stroke treatment.2014
- Author(s)
  10.Tatsuya Fukuta, Tomohiro Asai, Akihiko Sato, Kosuke Shimizu, Tetsuo Minamino, Hideo Tsukada, Naoto Oku
- Organizer
  The 2nd International Conference on Pharma and Food
- Place of Presentation
  静岡
- Year and Date
  2014-11-05
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Enhanced circulation of secondly injected PEGylated liposomes after injection of doxorubicin-encapsulatd PEGylated liposomes2013
- Author(s)
  Jantana Yahuafai, Yuri Kiyokawa, Yoshito Takeuchi, Daiki Saito, Kosuke Shimizu, Tomohiro Asai, Pongpun Siripong, Kenji Hyodo, Hiroshi Ishihara, Hiroshi Kikuchi, Naoto Oku
- Organizer
  The 5 th Conference
- Place of Presentation
  名古屋
- Year and Date
  2013-08-05
- Data Source
  KAKENHI-PROJECT-24659021
[Presentation] FK506封入PEG修飾リポソームによる脳虚血/再灌流障害治療2013
- Author(s)
  上戸由里佳、石井貴之、尾山大、安田和、福田達也、佐藤晶彦、清水広介、浅井知浩、南野哲男、奥直人
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Suppression of allergic response by antigen-modified liposomes encapsulating cytotoxic drugs2013
- Author(s)
  Kosuke Shimizu, Kanae Ichikawa, Takeo Urakami, Tomohiro Asai, Tatsuhiro Ishida, Hiroshi Kiwada, Naoto Oku
- Organizer
  The 5th Asian Arden Conference
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] スギ花粉症根治を目指したCryj1表面修飾リポソームの開発2013
- Author(s)
  斉藤大騎、松木孝太、伊藤あゆみ、清水広介、浅井知浩、奥直人
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] 脳梗塞に対する新規脳保護療法の構築に向けたリポソームDDSの応用2013
- Author(s)
  佐藤晶彦、福田達也、石井貴之、尾山大、安田和、上戸由里佳、清水広介、浅井知浩、南野哲男、奥直人
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] ファージライブラリーを用いた長期血中滞留性ペプチドの探索2013
- Author(s)
  清河友理、中田貴志、古屋恵一、清水広介、浅井知浩、奥直人
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24659021
[Presentation] Increased Half-life of secondly injected PEGylated liposomes in mice pretreated with doxorubicin-encapsulated PEGylated liposome2013
- Author(s)
  Jantana Yahuafai, Tomohiro Asai, Genki Nakamura, Yuri Kiyokawa, Yoshihito Takeuchi, Kosuke Shimizu, Pongpun Siripong, Kenji Hyodo, Hiroshi Ishihara, Hiroshi Kikuchi, Naoto Oku
- Organizer
  International Liposome Society 2013 Meeting Liposome Advances : Progress in Drug and Vaccine Delivery
- Place of Presentation
  London, UK
- Year and Date
  2013-12-14
- Data Source
  KAKENHI-PROJECT-24659021
[Presentation] Suppression of allergic responses by specific delivery of a cytotoxic drug to splenic B cells2013
- Author(s)
  Kosuke Shimizu, Kanae Ichikawa, Takeo Urakami, Tomohiro Asai, Tatsuhiro Ishida, Hiroshi Kiwada, Naoto Oku
- Organizer
  The 18th Shizuoka Forum on Health and Longevity
- Place of Presentation
  Shizuoka, Japan
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] Identification of a novel peptide targeting to human tumor vasculature for drug delivery2012
- Author(s)
  Takashi Nakada, Koji Hirashima, Yuri Kiyokawa, Kentaro Hatanaka, Kosuke Shimizu, Tomohiro Asai, Nanoto Oku
- Organizer
  Liposome Research Days
- Place of Presentation
  Hangzou, China
- Year and Date
  2012-10-09
- Data Source
  KAKENHI-PROJECT-24659021
[Presentation] FK506封入PEG修飾リポソームを用いた脳虚血再灌流障害治療2012
- Author(s)
  石井貴之、上戸由里佳、尾山大、安田和、福田達也、浅井知浩、清水広介、南野哲男、奥直人
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] リポソームDDS技術を応用した脳虚血/再灌流障害治療法の開発2012
- Author(s)
  石井貴之、浅井知浩、尾山大、福田達也、安田和、上戸由里佳、清水広介、南野哲男、奥直人
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22659010
[Presentation] リポソームDDSを応用した脳虚血時における新規脳保護戦略の構築2012
- Author(s)
  福田達也、石井貴之、尾山大、安田和、上戸由里佳、浅井知浩、清水広介、南野哲男、奥直人
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22659010
[Presentation] Antigen-decorated liposomes for the treatment of allergic diseases2012
- Author(s)
  Kosuke Shimizu, Kanae Ichikawa, Takeo Urakami, Tomohiro Asai, Tatsuhiro Ishida, Hiroshi Kiwada, Naoto Oku
- Organizer
  Liposome Research Days 2012
- Place of Presentation
  Hangzhou, China
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] Development of PEGylated liposomes encapsulating FK506 for the treatment of cerebral ischemia/reperfusion injury2012
- Author(s)
  Takayuki Ishii, Tomohiro Asai, Dai Oyama, Yurika Agato, Nodoka Yasuda, Tatsuya Fukuta, Kosuke Shimizu, Tetsuo Minamino, Naoto Oku
- Organizer
  Liposome Research Days 2012
- Place of Presentation
  Hangzhou, China
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] 脳梗塞に対する新規脳保護戦略構築に向けたリポソームDDSの応用2012
- Author(s)
  福田達也、石井貴之、尾山大、安田和、上戸由里佳、浅井知浩、清水広介、南野哲男、奥直人
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Treatment of cerebral ischemia/reperfusion injury with asialoerythropoietin　-modified PEGylated liposomes2012
- Author(s)
  Tatsuya Fukuta, Takayuki Ishii, Tomohiro Asai, Dai Oyama, Nodoka Yasuda, Kosuke Shimizu, Tetsuo Minamino, Naoto Oku
- Organizer
  Liposome Research Days 2012
- Place of Presentation
  Hangzhou, China
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Development of liposomes for complete cure of Japanese cedar pollinosis2012
- Author(s)
  Kota Matsuki, Ayumi Ito, Daiki Saito, Kosuke Shimizu, Tomohiro Asai, Naoto Oku
- Organizer
  Liposome Research Days 2012
- Place of Presentation
  Hangzhou, China
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] 脳虚血再灌流モデルラットにおけるFK506封入PEG修飾リポソームの薬理効果及び脳内挙動の解析2012
- Author(s)
  上戸由里佳、石井貴之、尾山大、安田和、福田達也、浅井知浩、清水広介、南野哲男、奥直人
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22659010
[Presentation] 逆標的化DDSを利用した新規スギ花粉症治療法の確立2012
- Author(s)
  松木孝太、伊藤あゆみ、斎藤大騎、清水広介、浅井知浩、奥　直人
- Organizer
  第34回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] FK506のリポソーム化による脳虚血/再灌流障害抑制効果の増強2012
- Author(s)
  上戸由里佳、石井貴之、尾山大、安田和、福田達也、佐藤晶彦、浅井知浩、清水広介、南野哲男、奥直人
- Organizer
  第58回日本薬学会東海支部総会･大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Identification of a novel peptide targeting to human tumor vasculature for drug delivery2012
- Author(s)
  T Nakada, K Hirashima, Y Kiyokawa, K Hatanaka, K Shimizu, T Asai, N Oku
- Organizer
  Liposome Research Days 2012
- Place of Presentation
  Hangzhou, China
- Data Source
  KAKENHI-PROJECT-24659021
[Presentation] スギ花粉症根治を可能とする免疫細胞標的化リポソームの開発2012
- Author(s)
  伊藤あゆみ、松木孝太、斉藤大騎、清水広介、浅井知浩、奥　直人
- Organizer
  第58回日本薬学会東海支部総会･大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24790047
[Presentation] Treatment of Cerebral Ischemia-Reperfusion Injury with Liposomal Asialo-Erythropoietin2011
- Author(s)
  Dai Oyama, Takayuki Ishii, Tomohiro Asai, Tatsuya Fukuta, Nodoka Yasuda, Kosuke Shimizu, Tetsuo Minamino, Naoto Oku
- Organizer
  Liposomes Jerusalem 2011
- Place of Presentation
  Jerusalem Israel
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-22659010
[Presentation] 脳虚血再灌流障害治療に向けたFK506封入PEG修飾リポソームの応用2011
- Author(s)
  安田和、石井貴之、尾山大、上戸由里佳、福田達也、浅井知浩、清水広介、南野哲男、奥直人
- Organizer
  第33回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  岡山
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-22659010
[Presentation] Application of liposomal DDS for the treatment of ischemia/reperfusion injury2011
- Author(s)
  Naoto Oku, Takayuki Ishii, Dai Oyama, Tatsuya Fukuta, Nodoka Yasuda, Kosuke Shimizu, Tomohiro Asai, Tetsuo Minamino
- Organizer
  International Liposome Society 2011 Meeting
- Place of Presentation
  London, UK
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22659010
[Presentation] リポソームDDSによるAsialo-erythropoietinの脳虚血再灌流障害抑制効果の増強2011
- Author(s)
  石井貴之、浅井知浩、福田達也、尾山大、安田和、清水広介、南野哲男、奥直人
- Organizer
  第27回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-22659010
[Presentation] Liposomal Drug Delivery System as a Potential Strategy for the Treatment of Cerebral Ischemia-Reperfusion Injury2011
- Author(s)
  Takayuki Ishii, Tomohiro Asai, Dai Oyama, Tatsuya Fukuta, Nodoka Yasuda, Kosuke Shimizu, Tetsuo Minamino, Naoto Oku
- Organizer
  Liposomes Jerusalem 2011
- Place of Presentation
  Jerusalem Israel
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-22659010
[Presentation] 腫瘍リンパ管新生が及ぼす薬物ナノキャリア腫瘍移行性への影響2010
- Author(s)
  清水広介, ら
- Organizer
  第74回日本生化学会中部支部例会・シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] Treatment of cerebral ischemia-reperfusion injury by liposomal drug delivery system2010
- Author(s)
  Takayuki Ishii, Dai Oyama, Tomohiro Asai, Kosuke Shimizu, Tetsuo Minamino, Naoto Oku
- Organizer
  LRD/LLMB 2010 Conference
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-22659010
[Presentation] Liposomal tumor targeting and tumor lymphangiogenesis.2010
- Author(s)
  Kosuke Shimizu, et al.
- Organizer
  LRD/LLMB 2010 Conference
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] Positron imaging of biodistribution of [11C]Me-EGCg2010
- Author(s)
  Kosuke Shimizu, et al.
- Organizer
  ICOS 2010 The 4th International Conference on O-CHA (Tea) Culture and Science
- Place of Presentation
  グランシップ(静岡)
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] 腫瘍リンパ管新生がリポソームのがん集積性に与える影響2010
- Author(s)
  清水広介, ら
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] Liposomal tumor targeting and tumor lymphangiogenesis2010
- Author(s)
  Kosuke Shimizu, et al.
- Organizer
  LRD/LLMB 2010 Conference
- Place of Presentation
  University of British Columbia
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] 腫瘍リンパ管新生が及ぼす薬物ナノキャリア腫瘍移行性への影響2010
- Author(s)
  清水広介, ら
- Organizer
  第74回日本生化学会中部支部例会・シンポジウム
- Place of Presentation
  名古屋大学医学部
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] 腫瘍リンパ管新生がリポソームのがん集積性に与える影響2010
- Author(s)
  清水広介, ら
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島あわぎんホール
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] 機能性リン脂質Phosphatidylinositolの体内動態解析と肥満抑制効果の検討2009
- Author(s)
  清水広介, ら
- Organizer
  第63回日本栄養・食糧学会大会
- Place of Presentation
  長崎新聞文化ホール
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] Mechanism of Temperature-dependent Antifungal Activity of AmBisome2009
- Author(s)
  Kosuke Shimizu, et al.
- Organizer
  36th Annual Meeting & Exposition of Controlled Release Society
- Place of Presentation
  Bella Center
- Year and Date
  2009-07-21
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] Tumor-targeting liposomal DDS and lymphagiogenesis.2008
- Author(s)
  Kosuke Shimizu, et al.
- Organizer
  11th Liposome Research Days Conference
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-07-20
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] Tumor-targeting Liposomal DDS and Lymphangiogenesis2008
- Author(s)
  Kosuke Shimizu, et.al.
- Organizer
  11^<th> Liposome Research Days Conference
- Place of Presentation
  横浜シンポジア(横浜)
- Year and Date
  2008-07-20
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] リポソームの腫瘍受動標的化におけるリンパ管新生の影響2008
- Author(s)
  清水広介, ら
- Organizer
  第24回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] リポソームの腫瘍受動標的化におけるリンパ管新生の影響2008
- Author(s)
  清水広介, ら
- Organizer
  第24回日本DDS学会
- Place of Presentation
  六本木アカデミーヒルズ(東京)
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-20790041
[Presentation] Neuroprotective Effect of PEGylated Liposomes Encapsulating FK506 on Cerebral Ischemia-reperfusion Injury.
- Author(s)
  Yurika Agato, Takayuki Ishii, Dai Oyama, Nodoka Yasuda, Tatsuya Fukuta, Akihiko Sato, Kosuke Shimizu, Tomohiro Asai, Tetsuo Minamino, Naoto Oku:
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Increased Half-life of secondly injected PEGylated liposomes in mice pretreated with doxorubicin-encapsulated PEGylated liposomes
- Author(s)
  Jantana Yafuafai, Tomohiro Asai, Genki Nakamura, Yuri Kiyokawa, Yoshihito Takeuchi, Kosuke Shimizu, Pongpun Siripong, Kenji Hyodo, Hiroshi Ishihara, Hiroshi Kikuchi, Naoto Oku
- Organizer
  International Liposome Society 2013 Meeting
- Place of Presentation
  London UK
- Data Source
  KAKENHI-PROJECT-24659021
[Presentation] Enhanced circulation of secondly injected PEGylated liposomes after injection of doxorubicin-encapsulatd PEGylated liposomes
- Author(s)
  Jantana Yahuafai, Yuri Kiyokawa, Yoshito Takeuchi, Daiki Saito, Kosuke Shimizu, Tomohiro Asai, Pongpun Siripong, Kenji Hyodo, Hiroshi Ishihara, Hiroshi Kikuchi, Naoto Oku
- Organizer
  The 5th Asian Arden Conference
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24659021
[Presentation] 脳虚血/再灌流障害治療を目的としたリポソームDDSの応用
- Author(s)
  石井貴之、尾山大、福田達也、安田和、上戸由里佳、佐藤晶彦、浅井知浩、清水広介、南野哲男、奥直人
- Organizer
  第22回DDSカンファランス
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Development of liposomal drug delivery system for ischemic stroke treatment before reperfusion of cerebral blood flow
- Author(s)
  Tatsuya Fukuta, Takayuki Ishii, Akihiko Sato, Yurika Agato, Kosuke Shimizu, Tomohiro Asai, Tetsuo Minamino, Naoto Oku
- Organizer
  Development of liposomal drug delivery system for ischemic stroke treatment before reperfusion of cerebral blood flow
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Liposomal drug delivery system as a pre-reperfusion therapy for ischemic stroke
- Author(s)
  Fukuta T, Ishii T, Sato A, Agato Y, Shimizu K, Asai T, Minamino T, Tsukada H, Oku N
- Organizer
  The 4th International Symposium on Artificial Oxygen Carriers
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] Liposomal drug delivery system for the treatment of ischemic stroke before restoration of cerebral blood flow
- Author(s)
  Tatsuya Fukuta, Tomohiro Asai, Akihiko Sato, Yurika Agato, Kosuke Shimizu, Hideo Tsukada, Naoto Oku
- Organizer
  International Liposome Society 2013 Meeting
- Place of Presentation
  London, UK
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] 脳梗塞新規治療戦略構築に向けたリポソームDDSの応用
- Author(s)
  福田達也、佐藤晶彦、清水広介、浅井知浩、南野哲男、塚田秀夫、奥直人
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23249005
[Presentation] NMDA受容体遮断薬内封リポソームを用いた脳虚血/再灌流障害治療による神経保護
- Author(s)
  上戸由里佳、石井貴之、菊地隆司、福田達也、清水広介、浅井知浩、奥直人
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23249005

1. OKU Naoto (10167322)

# of Collaborated Projects: 9 results

# of Collaborated Products: 52 results
2. ASAI Tomohiro (00381731)

# of Collaborated Projects: 9 results

# of Collaborated Products: 37 results
3. Magata Yasuhiro (20209399)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. 小出裕之 (60729177)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. 大多哲史 (30774749)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
6. TAKEDA Atsushi (90145714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Hoshi Yoko (50332383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 阪原晴海 (10187031)

# of Collaborated Projects: 1 results

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9. 鈴木千恵 (20637285)

# of Collaborated Projects: 1 results

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10. 馬渡健一 (70190577)

# of Collaborated Projects: 1 results

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11. 谷川ゆかり (20344202)

# of Collaborated Projects: 1 results

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12. 岡田英史 (40221840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 町田学 (40396916)

# of Collaborated Projects: 1 results

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14. 川口拓之 (60510394)

# of Collaborated Projects: 1 results

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15. 山岸覚 (40372362)

# of Collaborated Projects: 1 results

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16. 福田敦夫 (50254272)

# of Collaborated Projects: 1 results

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17. 清水一男 (90282681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
18. 榎本紀之 (50436961)

# of Collaborated Projects: 1 results

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19. 須田隆文 (30291397)

# of Collaborated Projects: 1 results

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20. 永田年 (90275024)

# of Collaborated Projects: 1 results

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21. 中村篤志 (50402243)

# of Collaborated Projects: 1 results

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22. 荒牧修平 (60907872)

# of Collaborated Projects: 1 results

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23. 中村和正 (20284507)

# of Collaborated Projects: 1 results

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24. 山田貴教 (10402265)

# of Collaborated Projects: 1 results

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25. 大澤恵 (10397391)

# of Collaborated Projects: 1 results

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26. 濱屋寧 (20436968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 石田竜弘 (50325271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 田代陽介 (30589528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. KANAZAWA Takanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 川島博人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 竹村泰司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIMIZU Kosuke 清水 広介

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Basic research of noise-canceling technology for molecular imaging utilizing DDSPrincipal Investigator

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警告を受けた循環がん細胞を強制退場させるレフェリーナノ粒子の創製Principal Investigator

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Basic research for development of a new drug for the treatment of myasthenia gravisPrincipal Investigator

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Innovative DDS medicine for the complete recovery from autoimmune diseasesPrincipal Investigator

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Development of tumor-targetable, enzyme-specific activatable fluorescent probe for early diagnosis of tumorPrincipal Investigator

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SHIMIZU Kosuke 清水広介