Saito Yasuhiro 齊藤康弘

… Alternative Names

SAITO Yasuhiro 齊藤康弘

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Researcher Number	30613004
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 政策・メディア研究科(藤沢), 特任准教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 慶應義塾大学, 政策・メディア研究科(藤沢), 特任准教授 2024: 慶應義塾大学, その他の研究科, 准教授 2019 – 2022: 慶應義塾大学, 政策・メディア研究科(藤沢), 特任講師 2014: 東京大学, 大学院医学系研究科, 助教 2012 – 2013: 東京大学, 医学(系)研究科(研究院), 助教 2011 – 2012: 東京大学, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / 0901:Oncology and related fields / Bacteriology (including mycology) / Bacteriology (including Mycology) Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Biological Sciences
Keywords	Principal Investigator 細胞極性タンパク質 / 乳がん / アミノ酸トランスポーター / オルガノイド / ストレス / 細胞極性 / 薬剤耐性乳がん細胞 / ER陽性乳がん / 薬剤耐性乳がん / ホルモン受容体陽性乳がん … More / 薬剤耐性 / ノックアウトマウス / 細菌エフェクター / ヘリコバクター・ピロリ菌 / SHP2 / CagA / ピロリ菌 / 胃がん … More Except Principal Investigator メタボローム解析 / 骨形成 / プラセントカイン / 母体環境 / 母体情報伝達 / 非症候群性口唇口蓋裂 / 顎顔面形成 / 胎盤 / シグナル伝達 / 細菌 / 癌 / 炎症 / ヘリコバクター・ピロリ / 胃がん / 感染症 / がん Less

複合的細胞ストレス研究におけるオルガノイド解析基盤の確立Principal Investigator
- Principal Investigator
  
  齊藤康弘
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
乳がん細胞における複合的細胞ストレス適応の分子機序の解明Principal Investigator
- Principal Investigator
  
  齊藤康弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
Preventive medicine of cleft lip and palate with placental functional regulation and placentocaines
- Principal Investigator
  
  楠山譲二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Tokyo Medical and Dental University
The molecular mechanisms of tamoxifen-resistance induction by intracellular amino acids in ER-positive breast cancerPrincipal Investigator
- Principal Investigator
  
  SAITO Yasuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Keio University
Molecular mechanisms of adaptation to nutrient stress in ER-positive breast cancerPrincipal Investigator
- Principal Investigator
  
  SAITO Yasuhiro
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Keio University
細菌EPIYAエフェクターが模倣する宿主タンパク質プラグミンの感染における役割Principal Investigator
- Principal Investigator
  
  齊藤康弘
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  The University of Tokyo
The pathophysiological function of Helicobacter pylori CagA oncoprotein that is processed in gastric epithelial cellsPrincipal Investigator
- Principal Investigator
  
  SAITO Yasuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
Host response as an enhancer of infection-associated cancer and its regulation
- Principal Investigator
  
  HATAKEYAMA Masanori
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2012 2011 2010

All Journal Article Presentation

[Journal Article] Comprehensive metabolome analysis of intracellular metabolites in cultured cells2022
- Author(s)
  Kudo Ryuhei、Igarashi Kaori、Soga Tomoyoshi、Ishikawa Takamasa、Saito Yasuhiro
- Journal Title
  
  STAR Protocols
  
  Volume: 3 Issue: 3 Pages: 101531-101531
- DOI
  10.1016/j.xpro.2022.101531
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07620
[Journal Article] Amino acid transporters as emerging therapeutic targets in cancer2021
- Author(s)
  Saito Yasuhiro、Soga Tomoyoshi
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 8 Pages: 2958-2965
- DOI
  10.1111/cas.15006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07620
[Journal Article] アミノ酸トランスポーターを標的とした個別化医療2021
- Author(s)
  齊藤康弘、曽我朋義
- Journal Title
  
  Precision Medicine
  
  Volume: 4 Pages: 18-21
- Data Source
  KAKENHI-PROJECT-20K07620
[Journal Article] Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulatRhoA-dependent actin cytoskeletal reorganization2011
- Author(s)
  Yamahashi Y, Saito Y, Murata-Kamiya N, Hatakeyama M
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 44576-44584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890037
[Journal Article] Conversion of Helicobacter pylori CagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21.2010
- Author(s)
  Saito, Y.
- Journal Title
  
  J.Exp.Med.
  
  Volume: 207 Pages: 2157-2174
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114002
[Presentation] 乳がんにおけるアミノ酸トランスポーターSLC7A5の病態生理学的役割とその機能制御2024
- Author(s)
  齊藤康弘
- Organizer
  文部科学省共同利用・共同研究システム形成事業学際領域展開ハブ形成プログラムキックオフシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K27441
[Presentation] ER陽性乳がん細胞において栄養ストレス環境下でHSPB1のリン酸化はLLGL2-SLC7A5複合体形成を促進する2023
- Author(s)
  鈴木結香子、曽我朋義、齊藤康弘
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K27441
[Presentation] ER陽性乳がん細胞においてHSPB1はLLGL2-SLC7A5複合体形成を介して細胞増殖を促進する2023
- Author(s)
  齊藤康弘、鈴木結香子、曽我朋義
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27441
[Presentation] 乳がん細胞におけるロイシン依存的細胞増殖の分子機序2023
- Author(s)
  齊藤康弘
- Organizer
  第17回日本アミノ酸学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27441
[Presentation] ER陽性乳がん細胞において栄養ストレス依存的なHSPB1のリン酸化はLLGL2-SLC7A5複合体形成を促進する2023
- Author(s)
  鈴木結香子、曽我朋義、齊藤康弘
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27441
[Presentation] 乳がん細胞におけるLLGL2によるアミノ酸トランスポーターの制御2022
- Author(s)
  齊藤康弘
- Organizer
  第8回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] 細胞極性タンパク質SCRIBはSLC3A2と相互作用しER陽性乳がんの増殖を制御する2022
- Author(s)
  齊藤康弘、植田幸嗣、曽我朋義、Muthuswamy Senthil
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] 乳がん細胞におけるアミノ酸の新たな病態生理学的役割2022
- Author(s)
  齊藤康弘
- Organizer
  鶴岡がん研究シンポジウム2022
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] 乳がんにおけるアミノ酸の病態生理学的役割2022
- Author(s)
  齊藤康弘
- Organizer
  第2回反分野的生物医療学会in湯布院
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] 乳がんにおけるアミノ酸の新たな病態生理学的役割2022
- Author(s)
  齊藤康弘
- Organizer
  第1回分子栄養生物学セミナーin鶴岡
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] Polarity proteins regulate amino acid uptake in ER+ breast cancer2021
- Author(s)
  齊藤康弘
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] 分岐鎖アミノ酸ロイシンによる乳がん細胞の増殖機構2021
- Author(s)
  齊藤康弘
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] アミノ酸ロイシンによる乳がん細胞の増殖機構2021
- Author(s)
  齊藤康弘
- Organizer
  FRIS/TI-FRIS Life Science Seminar 2021-2022
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] 細胞極性タンパク質はER陽性乳がん細胞においてアミノ酸取り込みを制御する2021
- Author(s)
  齊藤康弘
- Organizer
  第73回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] ER陽性乳がん細胞において細胞極性タンパク質LLGL2はロイシン依存的細胞増殖の重要分子である2020
- Author(s)
  齊藤康弘
- Organizer
  第79回　日本癌学会学術総会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] アミノ酸を標的とした乳がん治療を目指して2020
- Author(s)
  齊藤康弘
- Organizer
  第2回　日本質量分析学会東北談話会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] ER陽性乳がんにおけるロイシン取り込みとその治療標的としての可能性2020
- Author(s)
  齊藤康弘
- Organizer
  第79回　日本癌学会学術総会　腫瘍別シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] アミノ酸を標的とした乳がん治療を目指して2020
- Author(s)
  齊藤康弘
- Organizer
  第2回日本質量分析学会東北談話会
- Invited
- Data Source
  KAKENHI-PROJECT-19K23896
[Presentation] エストロジェン受容体陽性乳がん細胞において細胞極性タンパク質LLGL2はロイシン取り込みを制御する2020
- Author(s)
  齊藤康弘
- Organizer
  第1回癌学会・若手の会
- Data Source
  KAKENHI-PROJECT-19K23896
[Presentation] 乳がん細胞において細胞極性タンパク質 LLGL2 はアミノ酸の取り込みを制御する2020
- Author(s)
  齊藤康弘
- Organizer
  第72回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K23896
[Presentation] 乳がん細胞において細胞極性タンパク質 LLGL2 はアミノ酸の取り込みを制御する2020
- Author(s)
  齊藤康弘
- Organizer
  第72回　日本細胞生物学会大会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] ER陽性乳がんにおけるロイシン取り込みとその治療標的としての可能性2020
- Author(s)
  齊藤康弘
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K23896
[Presentation] エストロジェン受容体陽性乳がん細胞において細胞極性タンパク質LLGL2はロイシン取り込みを制御する2020
- Author(s)
  齊藤康弘
- Organizer
  第1回癌学会・若手の会
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] 秀吉に学ぶがん治療戦略2020
- Author(s)
  齊藤康弘
- Organizer
  第3回　Scienc-ome
- Invited
- Data Source
  KAKENHI-PROJECT-20K07620
[Presentation] ER陽性乳がん細胞において細胞極性タンパク質LLGL2はロイシン依存的細胞増殖の重要分子である2020
- Author(s)
  齊藤康弘
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K23896
[Presentation] Interaction of the Helicobacter py; pro CagA oncoprotein with SHP2 in the nucleus2012
- Author(s)
  Yasuhiro Saito
- Organizer
  第７１回日本癌学会総会
- Place of Presentation
  札幌文芸館、札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-22114002
[Presentation] Interaction of the Helicobacter pylori CagA oncoprotein with SHP2 in the nucleus.核内における Helicobacter pylori CagA がんタンパク質 - SHP2 相互作用2012
- Author(s)
  齊藤康弘、畠山昌則
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Involvement of multiple tyrosine kinases in antagonizing parafibromin-mediated activation of Wnt signaling by SHP2 複数のチロシンキナーゼによる SHP2/parafibromin 依存的 Wnt シグナル活性化の拮抗制御2012
- Author(s)
  高橋昌史、齊藤康弘、畠山昌則
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Interaction of the Helicobacter pylori CagA oncoprotein with SHP2 in the nucleus2012
- Author(s)
  齊藤康弘
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育文化会館、札幌市
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation2011
- Author(s)
  Saito Y
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PLANNED-22114002
[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation2011
- Author(s)
  齊藤康弘
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Pragmin is a human EPIYA-containing protein targeted by H. pylori CagA oncoprotein. 胃がん発症におけるヘリコバクター・ピロリ CagA とヒト Pragmin の EPIYA 配列を介した競合作用の意義2011
- Author(s)
  サファリファテメ、紙谷尚子、齊藤康弘、畠山昌則
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation.Helicobacter pylori CagA は上皮細胞極性破壊により異常な細胞増殖を誘導する2011
- Author(s)
  齊藤康弘、紙谷尚子、畠山昌則
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23890037

1. HATAKEYAMA Masanori (40189551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KAMIYA Naoko (40279352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. MUTOH Hiroyuki (50322392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TSUTSUMI Ryohei (50435872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKAHASHI Atsushi (00624496)

# of Collaborated Projects: 1 results

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6. 楠山譲二 (70596105)

# of Collaborated Projects: 1 results

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7. 中富満城 (10571771)

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8. 門間陽樹 (90633488)

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Saito Yasuhiro 齊藤 康弘

SAITO Yasuhiro 齊藤 康弘

Research Projects

Research Products

Co-Researchers

複合的細胞ストレス研究におけるオルガノイド解析基盤の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

乳がん細胞における複合的細胞ストレス適応の分子機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preventive medicine of cleft lip and palate with placental functional regulation and placentocaines

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The molecular mechanisms of tamoxifen-resistance induction by intracellular amino acids in ER-positive breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of adaptation to nutrient stress in ER-positive breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細菌EPIYAエフェクターが模倣する宿主タンパク質プラグミンの感染における役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pathophysiological function of Helicobacter pylori CagA oncoprotein that is processed in gastric epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Host response as an enhancer of infection-associated cancer and its regulation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Comprehensive metabolome analysis of intracellular metabolites in cultured cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Amino acid transporters as emerging therapeutic targets in cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] アミノ酸トランスポーターを標的とした個別化医療2021

Author(s)

Journal Title

Data Source

[Journal Article] Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulatRhoA-dependent actin cytoskeletal reorganization2011

Author(s)

Journal Title

Data Source

[Journal Article] Conversion of Helicobacter pylori CagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21.2010

Author(s)

Journal Title

Data Source

[Presentation] 乳がんにおけるアミノ酸トランスポーターSLC7A5の病態生理学的役割とその機能制御2024

Author(s)

Organizer

Data Source

[Presentation] ER陽性乳がん細胞において栄養ストレス環境下でHSPB1のリン酸化はLLGL2-SLC7A5複合体形成を促進する2023

Saito Yasuhiro 齊藤康弘

SAITO Yasuhiro 齊藤康弘