SAITO Yasuhiro 齊藤康弘

Researcher Number	30613004
Affiliation *help	2014 : 東京大学, 大学院医学系研究科, 助教 2012 – 2013 : 東京大学, 医学(系)研究科(研究院), 助教 2011 – 2012 : 東京大学, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Bacteriology (including mycology) Except Principal Investigator Biological Sciences
Keywords	Principal Investigator ピロリ菌 / ノックアウトマウス / 細菌エフェクター / CagA / 胃がん / ヘリコバクター・ピロリ菌 / SHP2 Except Principal Investigator 癌 / 感染症 / 炎症 … More

細菌EPIYAエフェクターが模倣する宿主タンパク質プラグミンの感染における役割Principal Investigator
- Principal Investigator
  
  齊藤康弘
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  The University of Tokyo
The pathophysiological function of Helicobacter pylori CagA oncoprotein that is processed in gastric epithelial cellsPrincipal Investigator
- Principal Investigator
  
  SAITO Yasuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
Host response as an enhancer of infection-associated cancer and its regulation
- Principal Investigator
  
  HATAKEYAMA Masanori
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2012 2011 2010

All Journal Article Presentation

[Journal Article] Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulatRhoA-dependent actin cytoskeletal reorganization2011
- Author(s)
  Yamahashi Y, Saito Y, Murata-Kamiya N, Hatakeyama M
- Journal Title
  
  J. Biol. Chem
  
  Volume : 286 Pages : 44576-44584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890037
[Journal Article] Conversion of Helicobacter pylori CagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21.2010
- Author(s)
  Saito, Y.
- Journal Title
  
  J.Exp.Med.
  
  Volume : 207 Pages : 2157-2174
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22114002
[Presentation] Interaction of the Helicobacter py; pro CagA oncoprotein with SHP2 in the nucleus2012
- Author(s)
  Yasuhiro Saito
- Organizer
  第７１回日本癌学会総会
- Place of Presentation
  札幌文芸館、札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-22114002
[Presentation] Interaction of the Helicobacter pylori CagA oncoprotein with SHP2 in the nucleus2012
- Author(s)
  齊藤康弘
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育文化会館、札幌市
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Interaction of the Helicobacter pylori CagA oncoprotein with SHP2 in the nucleus.核内における Helicobacter pylori CagA がんタンパク質 - SHP2 相互作用2012
- Author(s)
  齊藤康弘、畠山昌則
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Involvement of multiple tyrosine kinases in antagonizing parafibromin-mediated activation of Wnt signaling by SHP2 複数のチロシンキナーゼによる SHP2/parafibromin 依存的 Wnt シグナル活性化の拮抗制御2012
- Author(s)
  高橋昌史、齊藤康弘、畠山昌則
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation2011
- Author(s)
  Saito Y
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PLANNED-22114002
[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation.Helicobacter pylori CagA は上皮細胞極性破壊により異常な細胞増殖を誘導する2011
- Author(s)
  齊藤康弘、紙谷尚子、畠山昌則
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Pragmin is a human EPIYA-containing protein targeted by H. pylori CagA oncoprotein. 胃がん発症におけるヘリコバクター・ピロリ CagA とヒト Pragmin の EPIYA 配列を介した競合作用の意義2011
- Author(s)
  サファリファテメ、紙谷尚子、齊藤康弘、畠山昌則
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23890037
[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation2011
- Author(s)
  齊藤康弘
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-23890037

1. HATAKEYAMA Masanori (40189551)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
2. KAMIYA Naoko (40279352)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
3. MUTOH Hiroyuki (50322392)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. TSUTSUMI Ryohei (50435872)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. TAKAHASHI Atsushi (00624496)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

SAITO Yasuhiro 齊藤 康弘

Research Projects

Research Products

Co-Researchers

細菌EPIYAエフェクターが模倣する宿主タンパク質プラグミンの感染における役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pathophysiological function of Helicobacter pylori CagA oncoprotein that is processed in gastric epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Host response as an enhancer of infection-associated cancer and its regulation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulatRhoA-dependent actin cytoskeletal reorganization2011

Author(s)

Journal Title

Data Source

[Journal Article] Conversion of Helicobacter pylori CagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21.2010

Author(s)

Journal Title

Data Source

[Presentation] Interaction of the Helicobacter py; pro CagA oncoprotein with SHP2 in the nucleus2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Interaction of the Helicobacter pylori CagA oncoprotein with SHP2 in the nucleus2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Interaction of the Helicobacter pylori CagA oncoprotein with SHP2 in the nucleus.核内における Helicobacter pylori CagA がん タンパク質 - SHP2 相互作用2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Involvement of multiple tyrosine kinases in antagonizing parafibromin-mediated activation of Wnt signaling by SHP2 複数のチロシンキナーゼによる SHP2/parafibromin 依存的 Wnt シグナル活性化の拮抗制御2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation.Helicobacter pylori CagA は上皮細胞極性破 壊により異常な細胞増殖を誘導する2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Pragmin is a human EPIYA-containing protein targeted by H. pylori CagA oncoprotein. 胃がん発症におけるヘリコバクター・ピロリ CagA とヒト Pragmin の EPIYA 配列を介し た競合作用の意義2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

SAITO Yasuhiro 齊藤康弘

[Presentation] Interaction of the Helicobacter pylori CagA oncoprotein with SHP2 in the nucleus.核内における Helicobacter pylori CagA がんタンパク質 - SHP2 相互作用2012

[Presentation] Helicobacter pylori CagA oncoprotein targets epithelial polarity to elicit aberrant cell proliferation.Helicobacter pylori CagA は上皮細胞極性破壊により異常な細胞増殖を誘導する2011

[Presentation] Pragmin is a human EPIYA-containing protein targeted by H. pylori CagA oncoprotein. 胃がん発症におけるヘリコバクター・ピロリ CagA とヒト Pragmin の EPIYA 配列を介した競合作用の意義2011