Kono Susumu 河野晋

… Alternative Names

Kohno Susumu 河野晋

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Researcher Number	30625463
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, がん進展制御研究所, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 金沢大学, がん進展制御研究所, 助教 2016 – 2018: 金沢大学, がん進展制御研究所, 特任助教 2016: 金沢大学, がん進展制御研究所, 研究員 2015 – 2016: 金沢大学, がん進展制御研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology Except Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Tumor biology
Keywords	Principal Investigator RB / PGAM / ELOVL6 / 休眠細胞 / MYC / エピジェネティクス / KDM5A / グルコース代謝 / がん幹細胞 / 糖代謝 … More Except Principal Investigator … More レギュカルチン / グルタミン / 糖代謝 / コレステロール / がん幹細胞 / 代謝 / がん / がん抑制遺伝子 / PGAM / 脂質代謝 / 解糖系 / RB / がん代謝 Less

脂質クオリテイ制御による腫瘍微小環境ホット化機構の解明Principal Investigator
- Principal Investigator
  
  河野晋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
レギュカルチンの多機能性を基軸とした疾患発症メカニズムの解明と疾患治療法の開発
- Principal Investigator
  
  村田富保
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Meijo University
dormancy inducers and molecular mechanisms underlying late recurrence of breast cancerPrincipal Investigator
- Principal Investigator
  
  Kohno Susumu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Tumor progression through epigenetics remodeling by RB-PGAMPrincipal Investigator
- Principal Investigator
  
  Kohno Susumu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Analysis of reprogrammed metabolism by PGAM in cancer stem cell modelPrincipal Investigator
- Principal Investigator
  
  Kohno Susumu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Regulation of metabolism by RB tumor suppressor gene
- Principal Investigator
  
  Takahashi Chiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University

All 2023 2022 2021 2020 2018 2017 2016 2015 2014

All Journal Article Presentation Book Patent

[Book] 『代謝変化とエピジェテックス制御』「RBがん抑制遺伝子産物による細胞未分化性制御」2016
- Author(s)
  河野晋、北嶋俊輔、佐々木信成、髙橋智聡.
- Total Pages
  7
- Publisher
  生化学
- Data Source
  KAKENHI-PROJECT-26290037
[Book] マウス甲状腺C細胞および線維芽細胞は高度な未分化性を獲得する. BioMedサーカス.com 最新研究情報「執筆者自身による研究論文レビュー第35回」2015
- Author(s)
  北嶋俊輔, 河野晋, 髙橋智聡
- Publisher
  BioMedサーカス.com
- Data Source
  KAKENHI-PROJECT-26290037
[Journal Article] Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line2023
- Author(s)
  Noguchi Masafumi、Kohno Susumu、Pellattiero Anna、Machida Yukino、Shibata Keitaro、Shintani Norihito、Kohno Takashi、Gotoh Noriko、Takahashi Chiaki、Hirao Atsushi、Scorrano Luca、Kasahara Atsuko
- Journal Title
  
  Cell Death & Disease
  
  Volume: 14 Issue: 4 Pages: 1-10
- DOI
  10.1038/s41419-023-05768-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15017, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-23K18237, KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-22K20654, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-21H02671, KAKENHI-PROJECT-21H02761, KAKENHI-PROJECT-23K27437
[Journal Article] Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat2022
- Author(s)
  Oo Swe Mar、Oo Hein Ko、Takayama Hiroaki、Ishii Kiyo-aki、Takeshita Yumie、Goto Hisanori、Nakano Yujiro、Kohno Susumu、Takahashi Chiaki、Nakamura Hiroyuki、Saito Yoshiro、Matsushita Mami、Okamatsu-Ogura Yuko、Saito Masayuki、Takamura Toshinari
- Journal Title
  
  Cell Reports
  
  Volume: 38 Issue: 13 Pages: 110566-110566
- DOI
  10.1016/j.celrep.2022.110566
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-21K08572, KAKENHI-PROJECT-21K08573, KAKENHI-PROJECT-21K19503, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-22K11772, KAKENHI-PROJECT-22K19686, KAKENHI-PROJECT-19H03882, KAKENHI-PROJECT-21H02571, KAKENHI-PROJECT-18K11013, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-21K19321, KAKENHI-PLANNED-21H05270, KAKENHI-PROJECT-20H00488
[Journal Article] RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia2022
- Author(s)
  Pham Loc Thi、Peng Hui、Ueno Masaya、Kohno Susumu、Kasada Atuso、Hosomichi Kazuyoshi、Sato Takehiro、Kurayoshi Kenta、Kobayashi Masahiko、Tadokoro Yuko、Kasahara Atsuko、Shoulkamy Mahmoud I.、Xiao Bo、Worley Paul F.、Takahashi Chiaki、Tajima Atsushi、Hirao Atsushi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 621 Pages: 74-79
- DOI
  10.1016/j.bbrc.2022.06.089
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08448, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H01356, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07566, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K16264, KAKENHI-PUBLICLY-21H00342
[Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner2021
- Author(s)
  Nomura Naho、Ito Chiaki、Ooshio Takako、Tadokoro Yuko、Kohno Susumu、Ueno Masaya、Kobayashi Masahiko、Kasahara Atsuko、Takase Yusuke、Kurayoshi Kenta、Si Sha、Takahashi Chiaki、Komatsu Masaaki、Yanagawa Toru、Hirao Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1666-1679
- DOI
  10.1038/s41598-021-81076-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06657, KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-20K07566, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-19K17824, KAKENHI-PROJECT-19H03846, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K07558
[Journal Article] Chemical inducer of regucalcin attenuates lipopolysaccharide‐induced inflammatory responses in pancreatic MIN6 β‐cells and RAW264.7 macrophages2021
- Author(s)
  Murata Tomiyasu、Hashimoto Kazunori、Kohno Susumu、Takahashi Chiaki、Yamaguchi Masayoshi、Ito Chihiro、Masataka Itoigawa、Kojima Roji、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  FEBS Open Bio
  
  Volume: 12 Issue: 1 Pages: 175-191
- DOI
  10.1002/2211-5463.13321
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-19K07092
[Journal Article] Treatment of Retinoblastoma 1?Intact Hepatocellular Carcinoma With Cyclin‐Dependent Kinase 4/6 Inhibitor Combination Therapy2021
- Author(s)
  Sheng Jindan、Kohno Susumu、Okada Nobuhiro、Okahashi Nobuyuki、Teranishi Kana、Matsuda Fumio、Shimizu Hiroshi、Linn Paing、Nagatani Naoko、Yamamura Minako、Harada Kenichi、Horike Shin‐ichi、Inoue Hiroshi、Yano Seiji、Kumar Sharad、Kitajima Shunsuke、Ajioka Itsuki、Takahashi Chiaki
- Journal Title
  
  Hepatology
  
  Volume: 74 Issue: 4 Pages: 1971-1993
- DOI
  10.1002/hep.31872
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07365, KAKENHI-PUBLICLY-20H04943, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-20K07612
[Journal Article] Cytotoxic activity of dimeric acridone alkaloids derived from Citrus plants towards human leukaemia HL-60 cells2020
- Author(s)
  Murata Tomiyasu、Kohno Susumu、Ogawa Kazuma、Ito Chihiro、Itoigawa Masataka、Ito Masafumi、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  Journal of Pharmacy and Pharmacology
  
  Volume: 72 Issue: 10 Pages: 1445-1457
- DOI
  10.1111/jphp.13327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-19H01889, KAKENHI-PROJECT-19K07092
[Journal Article] Regucalcin enhances adipocyte differentiation and attenuates inflammation in 3T3‐L1 cells2020
- Author(s)
  Murata Tomiyasu、Yamaguchi Masayoshi、Kohno Susumu、Takahashi Chiaki、Risa Watanabe、Hatori Kanna、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  FEBS Open Bio
  
  Volume: 10 Issue: 10 Pages: 1967-1984
- DOI
  10.1002/2211-5463.12947
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-19K07092
[Journal Article] Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion2020
- Author(s)
  Kohno Susumu、Linn Paing、Nagatani Naoko、Watanabe Yoshihiro、Kumar Sharad、Soga Tomoyoshi、Takahashi Chiaki
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 34 Pages: 5690-5707
- DOI
  10.1038/s41388-020-1381-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-16H06276
[Journal Article] Peripubertal high‐fat diet promotes c‐Myc stabilization in mammary gland epithelium2020
- Author(s)
  Kulathunga Nilakshi、Kohno Susumu、Linn Paing、Nishimoto Yuuki、Horike Shin‐ichi、Zaraiskii Mikhail I.、Kumar Sharad、Muranaka Hayato、Takahashi Chiaki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 7 Pages: 2336-2348
- DOI
  10.1111/cas.14492
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555
[Journal Article] Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD22018
- Author(s)
  Nishimura Tatsunori、Nakata Asuka、Chen Xiaoxi、Nishi Kurumi、Meguro-Horike Makiko、Sasaki Soichiro、Kita Kenji、Horike Shin-ichi、Saitoh Kaori、Kato Keiko、Igarashi Kaori、Murayama Takahiko、Kohno Susumu、Takahashi Chiaki、Mukaida Naofumi、Yano Seiji、Soga Tomoyoshi、Tojo Arinobu、Gotoh Noriko
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 14 Pages: 2464-2481
- DOI
  10.1038/s41388-018-0589-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K19587, KAKENHI-PROJECT-17K14992, KAKENHI-PROJECT-17K15021, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-17H03576
[Journal Article] Regucalcin confers resistance to amyloid-β toxicity in neuronally differentiated PC12 cells2018
- Author(s)
  Murata Tomiyasu、Yamaguchi Masayoshi、Kohno Susumu、Takahashi Chiaki、Kakimoto Mitsumi、Sugimura Yukiko、Kamihara Mako、Hikita Kiyomi、Kaneda Norio
- Journal Title
  
  FEBS Open Bio
  
  Volume: 8 Issue: 3 Pages: 349-360
- DOI
  10.1002/2211-5463.12374
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PROJECT-16K08252
[Journal Article] The RB?IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity2017
- Author(s)
  Kitajima S、Yoshida A、Kohno S、Li F、Suzuki S、Nagatani N、Nishimoto Y、Sasaki N、Muranaka H、Wan Y、Thai T C、Okahashi N、Matsuda F、Shimizu H、Nishiuchi T、Suzuki Y、Tominaga K、Gotoh N、Suzuki M、Ewen M E、Barbie D A、Hirose O、Tanaka T、Takahashi C
- Journal Title
  
  Oncogene
  
  Volume: 36 Issue: 36 Pages: 5145-5157
- DOI
  10.1038/onc.2017.124
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-16J40231, KAKENHI-PROJECT-17J06037, KAKENHI-PROJECT-17H03576
[Journal Article] MicroRNA-140 mediates RB tumor suppressor function to control stem cell-like activity through interleukin-6.2017
- Author(s)
  Yoshida A, Kitajima S, Li F, Chaoyang C, Yujiro T, Susumu K, Wan Y, Naoyuki H, Hayato M, Nishimoto Y, Nagatani N, Nishiuchi T, Thai T C, Suzuki S, Nakao S, Tanaka T, Hirose O, Barbie D A and Takahashi C.
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中 Issue: 8 Pages: 13872-85
- DOI
  10.18632/oncotarget.14681
- NAID
  120006226780
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-26430105, KAKENHI-PROJECT-16KK0197, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-17H03576
[Journal Article] A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling2017
- Author(s)
  Muranaka H、Hayashi A、Minami K、Kitajima S、Kohno S、Nishimoto Y、Nagatani N、Suzuki M、Kulathunga L A N、Sasaki N、Okada N、Matsuzaka T、Shimano H、Tada H、Takahashi C
- Journal Title
  
  Oncogenesis
  
  Volume: 6 Issue: 6 Pages: e350-e350
- DOI
  10.1038/oncsis.2017.51
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-17J06037, KAKENHI-PROJECT-17H03576
[Journal Article] Glucoraphanin ameliorates obesity and insulin resistance through adipose tissue browning and reduction of metabolic endotoxemia in mice.2017
- Author(s)
  Nagata N, Xu L, Kohno S, Ushida Y, Aoki Y, Umeda R, Fuke N, Zhuge F, Ni Y, Nagashimada M, Takahashi C, Suganuma H, Kaneko S and Ota T.
- Journal Title
  
  Diabetes
  
  Volume: 印刷中 Issue: 5 Pages: 1222-1236
- DOI
  10.2337/db16-0662
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H05345, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-15K00813, KAKENHI-PROJECT-17K19586, KAKENHI-PROJECT-17K14992, KAKENHI-PUBLICLY-17H05615, KAKENHI-PROJECT-16H03035, KAKENHI-PROJECT-17H03576
[Journal Article] RB tumor suppressor functions shared by stem cell and cancer cell strategies.2016
- Author(s)
  Kohno S, Kitajima S, Sasaki N and Takahashi C.
- Journal Title
  
  World J Stem Cells
  
  Volume: 8 Issue: 4 Pages: 170-184
- DOI
  10.4252/wjsc.v8.i4.170
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-15K18404
[Journal Article] Therapeutic strategy for targeting aggressive malignant gliomas by disrupting their energy balance.2016
- Author(s)
  Hegazy AM, Yamada D, Kobayashi M, Kohno S, Ueno M, Ali MA, Ohta K, Tadokoro Y, Ino Y, Todo T, Soga T, Takahashi C and Hirao A.
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Pages: 170-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290037
[Journal Article] Metabolic characterization of cultured mammalian cells by mass balance analysis, tracer labeling experiments and computer-aided simulations.2015
- Author(s)
  Okahashi N, Kohno S, Kitajima S, Matsuda F, Takahashi C, Shimizu H.
- Journal Title
  
  J Biosci Bioeng.
  
  Volume: 120 Issue: 6 Pages: 725-731
- DOI
  10.1016/j.jbiosc.2015.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18404, KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-15J05988, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-26290037
[Journal Article] Undifferentiated State Induced by Rb-P53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts2015
- Author(s)
  Kitajima S, Kohno S, Kondoh A, Sasaki N, Nishimoto Y, Li F, Mohammed MS, Muranaka H, Nagatani N, Suzuki M, Kido Y, Takahashi C
- Journal Title
  
  STEM CELLS
  
  Volume: - Issue: 5 Pages: 1657-1669
- DOI
  10.1002/stem.1971
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25830076, KAKENHI-PROJECT-25830077, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-15K18404, KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26290037
[Journal Article] An in vitro system to characterize prostate cancer progression identified signaling required for self-renewal.2015
- Author(s)
  Salah M, Nishimoto Y, Kohno S, Kondoh A, Kitajima S, Muranaka H, Nishiuchi T, Ibrahim A, Yoshida A, Takahashi C.
- Journal Title
  
  Mol Carcinog.
  
  Volume: in press Issue: 12 Pages: 1974-1989
- DOI
  10.1002/mc.22444
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18404, KAKENHI-PUBLICLY-15H01487, KAKENHI-PROJECT-26640070, KAKENHI-PROJECT-26290037
[Patent] ＲＢ１陽性癌の治療用医薬組成物及びキット2020
- Inventor(s)
  高橋智聡、河野晋、盛金丹
- Industrial Property Rights Holder
  高橋智聡、河野晋、盛金丹
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB欠失による脆弱性を標的とした前立腺がん治療法の探索.2022
- Author(s)
  河野晋, 曽我朋義,高橋智聡.
- Organizer
  第8回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] PDACに対するCdk 4/6阻害療法の応用.2022
- Author(s)
  張園園, Gothwal KS, 河野晋, 盛金丹, 高橋智聡.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] SUCLA2遺伝子欠失前立腺がんに対するthymoquinoneの治療効果.2022
- Author(s)
  河野晋, 高橋智聡.
- Organizer
  第66回香料・テルペンおよび精油化学に関する討論会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] Targeting cancers carrying RB1-SUCLA2 deletion.2022
- Author(s)
  Takahashi C, Linn P, MishiroK, Kunishima M, Watanabe Y and Kohno S.
- Organizer
  Cold Spring Harbor Laboratory Meetings
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB欠失による脆弱性を標的とした前立腺がん治療法の探索.2022
- Author(s)
  河野晋, 高橋智聡.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] A mutant p53 P72R driven modulation of CXCR5-CXCL13 axis in human B cell lymphoma-migratio.2022
- Author(s)
  Gothwal KS, Kohno S, Sato A and Takahashi C.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] Application of CDK4/6 inhibition therapies to PDACs.2022
- Author(s)
  Zhang Y, Gothwal KS, Kohno S, Sheng J, Takahashi C.
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB欠損はERK経路の不活性化を介してMYCを不安定化させる2022
- Author(s)
  キョウ麟祥, Dominic Chih-Cheng Voon, 高橋智聡, 河野晋.
- Organizer
  日本生化学会北陸支部第40回大会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] Application of CDK4/6 inhibition therapies to PDACs.2022
- Author(s)
  Zhang Y, Gothwal KS, Kohno S, Sheng J, Takahashi C.
- Organizer
  第17回生命医科学研究所ネットワーク国際シンポジウム/令和4年度金沢国際がん生物学シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 loss.2021
- Author(s)
  Kohno Susumu, Paing Linn, Mishiro Kenji, Kunishima Munetaka, Watanabe Yoshihiro and Takahashi Chiaki.
- Organizer
  AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] Pharmacologically targetable metabolic vulnerability in prostate cancer carrying RB1-SUCLA2 deletion.2021
- Author(s)
  Kohno Susumu, Paing Linn, Soga Tomoyoshi, Takahashi Chiaki.
- Organizer
  Keystone symposia tumor metabolism and microenvironment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB-コレステロールによる未分化性維持機構の解明2021
- Author(s)
  河野晋, 佐々木信成, 高橋智聡
- Organizer
  第94回日本生化学大
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB1-SUCLA2欠失による代謝脆弱性を標的とした前立腺がん治療法の開発2021
- Author(s)
  河野晋, 高橋智聡
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB欠損に付随する代謝遺伝子欠損を標的とした治療法の探索2020
- Author(s)
  河野晋
- Organizer
  第1回日本癌学会若手の会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] NFYAによる乳がん悪性化機構への影響2020
- Author(s)
  植木ちひろ、辻本剛己、河野晋、高橋智聡、岡田宣宏
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] 進行前立腺がんにおけるRB1-SUCLA2遺伝子欠失を標的とする新規治療2020
- Author(s)
  高橋智聡、Paing Linn、曽我朋義、河野晋
- Organizer
  第58回日本癌治療学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB1-SUCLA2 欠損による代謝脆弱性を標的とした前立腺がん治療法の探索2020
- Author(s)
  河野晋、曽我朋義、高橋智聡
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] RB欠損に付随する代謝遺伝子欠損を標的とした治療法の探索2020
- Author(s)
  河野晋
- Organizer
  第2回金沢大学がん進展制御研究所・国立がん研究センター研究所若手研究発表会
- Data Source
  KAKENHI-PROJECT-20K07612
[Presentation] KDM5AとRBが制御する代謝分子の探索2018
- Author(s)
  3.河野晋, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡.
- Organizer
  第6回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] ストン脱メチル化酵素KDM5AとRBが制御する代謝分子の探索.2018
- Author(s)
  河野晋, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] RB controls differentiation through positive regulation of phosphoglycerate mutases.2018
- Author(s)
  Kohno S and Takahashi C.
- Organizer
  Abcam Cancer and Metabolism conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] ヒストン脱メチル化酵素KDM5AとRBが制御する代謝分子の探索.2018
- Author(s)
  河野晋, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡.
- Organizer
  第1回金沢大学がん進展制御研究所・国立がん研究センター研究所若手研究発表会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] 悪性進展過程におけるRBの代謝調節機能2017
- Author(s)
  河野晋, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] 前立腺がんにおけるRBホモ欠損に伴う脆弱性の獲得2017
- Author(s)
  河野晋, Paing Linn, 髙橋智聡
- Organizer
  第5回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-17K14992
[Presentation] Metabolic rewiring in Rb deficient cells during cancer progression.2016
- Author(s)
  Kohno S, Okahashi N, Kitajima S Suzuki S, Tanaka T, Matsuda F, Shimizu H and Takahashi C.
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  New Orleans USA/Ernest N. Morial Convention Center
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] CONTROL OF GLUCOSE METABOLISM BY RB.2016
- Author(s)
  Kohno S, Takahashi C
- Organizer
  Translational research in cancer cell metabolism
- Place of Presentation
  Palacio Euskalduna Jauregia /ビルバオスペイン
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Phosphoglyceratemutases (PGAMs) mediate RB function to control differentiation.2016
- Author(s)
  Kohno S and Takahashi C
- Organizer
  Fourth International Rb Meeting
- Place of Presentation
  コロンバス　オハイオ州
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Metabolic rewiring in Rb deficient cells during cancer progression2016
- Author(s)
  Kohno S, Okahashi N, Kitajima S Suzuki S, Tanaka T, Matsuda F, Shimizu H and Takahashi C.
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  New Orleans USA
- Year and Date
  2016-04-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] RB function in controlling glycolysis.2016
- Author(s)
  Kohno S, Kitajima S and Takahashi C.
- Organizer
  Keystone Symposia
- Place of Presentation
  Banff, Canada/Fairmont Banff Springs
- Year and Date
  2016-02-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Phosphoglyceratemutases (PGAMs) mediate RB function to control differentiation.2016
- Author(s)
  Kohno S and Takahashi C.
- Organizer
  Fourth International Rb Meeting
- Place of Presentation
  Hilton Columbus Downtown /コロンバス　オハイオ州
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RBがん抑制遺伝子による代謝制御と細胞未分化性2016
- Author(s)
  髙橋智聡, 北嶋俊輔, 河野晋
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都/京都テルサ
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Control of glucose metabolism by RB2016
- Author(s)
  Kohno S　and Takahashi C
- Organizer
  Translational research in cancer cell metabolism
- Place of Presentation
  ビルバオスペイン
- Year and Date
  2016-10-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] RBの中心炭素代謝制御機能2016
- Author(s)
  河野晋, 髙橋智聡
- Organizer
  第4回がんと代謝研究会
- Place of Presentation
  鹿児島
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Rb不活性化による代謝リワイヤリング機構の解明2015
- Author(s)
  河野晋，岡橋伸幸，北嶋俊輔，鈴木佐和子，田中知明，松田史生，清水浩，高橋智聡
- Organizer
  平成27年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科/蓼科グランドホテル
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Rb不活性化による代謝リワイヤリング機構の解明2015
- Author(s)
  河野晋，岡橋伸幸，北嶋俊輔，鈴木佐和子，田中知明，松田史生，清水浩，高橋智聡
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸/神戸ポートアイランド
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Rb不活性化による代謝リワイヤリング機構の解明2015
- Author(s)
  河野晋，岡橋伸幸，北嶋俊輔，鈴木佐和子，田中知明，松田史生，清水浩，高橋智聡
- Organizer
  第3回がんと代謝研究会
- Place of Presentation
  金沢/石川県立音楽堂
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] The metabolic function of RB in controlling mevalonate (MVA) pathway regulates tumor progression2015
- Author(s)
  Sasaki N, Kitajima S, Muranaka H, Shamma A, Kohno S, Takahashi C
- Organizer
  Keystone Symposia
- Place of Presentation
  Vancouver・Canada・Fairmont Hotel
- Year and Date
  2015-01-16
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Rb不活性化に伴うメタボリックリワイヤリング機構の解明2015
- Author(s)
  河野晋，北嶋俊輔，鈴木佐和子，田中知明，佐々木信成，村中勇人，高橋智聡
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋/名古屋国際会議場
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] Control of cellular metabolism by tumor suppressors2015
- Author(s)
  Susumu Kohno
- Organizer
  2015 Kanazawa University Cancer Research Institute Fudan University Shanghai Cancer Center Joint Symposium
- Place of Presentation
  金沢/金沢大学　医学部記念館
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K18404
[Presentation] The metabolic function of RB in controlling mevalonate (MVA) pathway and tumor progression.2014
- Author(s)
  Sasaki N, Muranaka H, Kitajima S, Kohno S, Shamma A and Takahashi C
- Organizer
  第37回日本癌学会学術総会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Rbによるサイトカインを介したがん悪性化制御機構の解明2014
- Author(s)
  北嶋俊輔, 吉田晶代, 河野晋, 鈴木佐和子, 田中知明, 後藤典子, 髙橋智聡
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RBによるメバロン酸経路を介したがん悪性進展制御機構.2014
- Author(s)
  佐々木信成, 村中勇人, 北嶋俊輔, 河野晋, Shamma A, 髙橋智聡
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RBの中心代謝制御機能2014
- Author(s)
  河野晋, 北嶋俊輔, 吉田晶代, 鈴木佐和子, 田中知明, 佐々木信成, 村中勇人, 髙橋智聡
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] がん抑制遺伝子RBによるSREBP-1の制御とがんにおける役割の解析2014
- Author(s)
  村中勇人, 北嶋俊輔, 佐々木信成, 河野晋, 吉田晶代, 丹下正一朗, 鈴木健之, 林昭夫, 多田秀昭, Shamma A, 髙橋智聡
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川県・横浜市・パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] RB不活性化によって誘導されるがん幹細胞様未分化状態におけるPgam2の役割2014
- Author(s)
  河野晋, 北嶋俊輔, 佐々木信成, 村中勇人, 鈴木佐和子, 田中知明, 岡橋伸幸, 松田史生, 清水浩, 髙橋智聡
- Organizer
  第2回がんと代謝研究会
- Place of Presentation
  東京都・葛飾区・東京理科大学
- Year and Date
  2014-07-16
- Data Source
  KAKENHI-PROJECT-26290037
[Presentation] Reductive glutamine metabolism in p53-null soft tissue sarcoma cells.2014
- Author(s)
  Okahashi N, Matsuda F, Kohno S, Takahashi C and Shimizu H.
- Organizer
  Metabolomics 2014.
- Place of Presentation
  山形県・鶴岡市・慶応大学鶴岡キャンパス
- Year and Date
  2014-06-05
- Data Source
  KAKENHI-PROJECT-26290037

1. Takahashi Chiaki (50283619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. Hayashi Naoyuki (50253456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. Kitajima Syunsuke (90566465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
4. Shamma Awad (50402839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. Sasaki Nobunari (40415170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 村田富保 (80285189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 寺前純吾 (90351395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 橋本和宜 (10816242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKAMURA Toshinari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. HORIKE Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 笠原敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 田所優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 町田雪乃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kono Susumu 河野 晋

Kohno Susumu 河野 晋

Research Projects

Research Products

Co-Researchers

脂質クオリテイ制御による腫瘍微小環境ホット化機構の解明Principal Investigator

Principal Investigator

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レギュカルチンの多機能性を基軸とした疾患発症メカニズムの解明と疾患治療法の開発

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dormancy inducers and molecular mechanisms underlying late recurrence of breast cancerPrincipal Investigator

Principal Investigator

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Review Section

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Tumor progression through epigenetics remodeling by RB-PGAMPrincipal Investigator

Principal Investigator

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Analysis of reprogrammed metabolism by PGAM in cancer stem cell modelPrincipal Investigator

Principal Investigator

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Regulation of metabolism by RB tumor suppressor gene

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[Book] 『代謝変化とエピジェテックス制御』「RBがん抑制遺伝子産物による細胞未分化性制御」2016

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[Book] マウス甲状腺C細胞および線維芽細胞は高度な未分化性を獲得する. BioMedサーカス.com 最新研究情報「執筆者自身による研究論文レビュー 第35回」2015

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[Journal Article] Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line2023

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[Journal Article] Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat2022

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[Journal Article] RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia2022

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[Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner2021

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[Journal Article] Chemical inducer of regucalcin attenuates lipopolysaccharide‐induced inflammatory responses in pancreatic MIN6 β‐cells and RAW264.7 macrophages2021

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[Journal Article] Treatment of Retinoblastoma 1?Intact Hepatocellular Carcinoma With Cyclin‐Dependent Kinase 4/6 Inhibitor Combination Therapy2021

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Kono Susumu 河野晋

Kohno Susumu 河野晋

[Book] マウス甲状腺C細胞および線維芽細胞は高度な未分化性を獲得する. BioMedサーカス.com 最新研究情報「執筆者自身による研究論文レビュー第35回」2015