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tajima yosuke  田島 陽介

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Tajima Yosuke  田島 陽介

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Researcher Number 30757505
Other IDs
Affiliation (Current) 2025: 新潟大学, 医歯学総合研究科, 客員研究員
Affiliation (based on the past Project Information) *help 2023: 新潟大学, 医歯学総合研究科, 客員研究員
2022 – 2023: 新潟大学, 医歯学系, 助教
2022 – 2023: 新潟大学, 医歯学総合病院, 助教
2018 – 2021: 藤田医科大学, 医学部, 講師
2016 – 2018: 新潟大学, 医歯学総合病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 55020:Digestive surgery-related / Digestive surgery
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Digestive surgery
Keywords
Principal Investigator
大腸癌 / 16S rRNA遺伝子解析 / 腸内細菌叢 / 低分化胞巣 / 簇出 / 上皮間葉移行 / Budding / PDC / PTEN / 粘膜層バリア … More / 16S rRNA解析 / 炎症性発癌 / 細菌叢 / 粘液層 / α多様性 / カルノア固定 / 粘液 / 機能性食品 / バクテリオシン / 回腸嚢炎 / 抗菌性機能食品 / プロバイオティクス / 過酸化水素 / 乳酸 / 乳酸菌 / MRSA / ヨーグルト … More
Except Principal Investigator
大腸癌 / Radiomics / Radiogenomics / 発癌メカニズム / スフィンゴシン-1-リン酸 / 発癌 / 脂質メディエーター / 潰瘍性大腸炎 / 大腸がん / 変異シグネチャー / 粘液形質 / BRAF変異 / ゲ ノム解析 / 16S rRNA遺伝子解析 / DNA付加体 / ゲノム解析 / 高次元データ解析 / 変異シグネチャー解析 / 癌遺伝子異常 / 腫瘍内細菌叢 / 側方リンパ節転移 / 予測モデル / 側方リンパ節 / 直腸癌 / Random forest / 機械学習 / mutational signature / 大腸癌肝転移 / 腸内細菌叢 / 細菌叢 / 炎症 / 回腸嚢炎 / 腫瘍内リンパ球浸潤 / 低分化胞巣 / TMB-H / SMAD4 / SMAD2 / ACVR2A / TGFBR2 / TGF-β / S1P / 炎症性発癌 / 遺伝子解析 / スフィンゴシン1リン酸 / 炎症性腸疾患 Less
  • Research Projects

    (10 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (32 People)
  •  BRAF変異陽性の大腸癌における分子病理学的特徴を加味した新しい分類法の確立

    • Principal Investigator
      中野 麻恵
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  大腸癌の変異シグネチャーを予測するRadiogenomics解析法の確立

    • Principal Investigator
      松本 瑛生
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  PTEN遺伝子変異による上皮間葉移行に着目した大腸癌の簇出・低分化胞巣の機序解明Principal Investigator

    • Principal Investigator
      田島 陽介
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Radiogenomicsによる直腸癌側方リンパ節転移の高精度予測モデルの開発

    • Principal Investigator
      中野 雅人
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  腫瘍内細菌叢が引き起こす癌遺伝子異常の同定と変異シグネチャー解析による要因の解明

    • Principal Investigator
      若井 俊文
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Niigata University
  •  Pathogenesis of pouchitis after ileal pouch anal anastomosis for ulcerative colitis: Analysis of intestinal microbiota and lipid mediators.

    • Principal Investigator
      Kameyama Hitoshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Bacterial composition analysis in colorectal tissue is affected by the degree of mucus adhesionPrincipal Investigator

    • Principal Investigator
      Tajima Yosuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Fujita Health University
  •  The new classification of colorectal cancer focusing on differences of molecular mechanisms in TGF-b signal pathway

    • Principal Investigator
      Shimada Yoshifumi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Niigata University
  •  Role of lipid mediator in colitis-associated cancer

    • Principal Investigator
      Kameyama Hitoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University
  •  A new treatment for postoperative intractable inflammatory condition focusing on antibacterial effect and intestinal regulation of yogurtPrincipal Investigator

    • Principal Investigator
      Tajima Yosuke
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Niigata University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Mucin phenotype and genetic alterations in non-V600E BRAF-mutated colorectal cancer2024

    • Author(s)
      Ozeki Hikaru、Shimada Yoshifumi、Nakano Mae、Kondo Shuhei、Ohashi Riuko、Miwa Yamato、Yamai Daisuke、Matsumoto Akio、Abe Kaoru、Tajima Yosuke、Ichikawa Hiroshi、Sakata Jun、Takii Yasumasa、Sugai Mika、Nagai Takahiro、Ling Yiwei、Okuda Shujiro、Wakai Toshifumi
    • Journal Title

      Human Pathology

      Volume: 145 Pages: 71-79

    • DOI

      10.1016/j.humpath.2024.02.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K17850, KAKENHI-PROJECT-23K08189
  • [Journal Article] Clinical significance of metastatic tumor deposit foci in rectal cancer in the lateral pelvic lymph node area2023

    • Author(s)
      Yamai Daisuke、Shimada Yoshifumi、Nakano Masato、Ozeki Hikaru、Matsumoto Akio、Abe Kaoru、Tajima Yosuke、Nakano Mae、Ichikawa Hiroshi、Sakata Jun、Nagai Takahiro、Ling Yiwei、Okuda Shujiro、Watanabe Gen、Nogami Hitoshi、Maruyama Satoshi、Takii Yasumasa、Wakai Toshifumi
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 28 Issue: 10 Pages: 1388-1397

    • DOI

      10.1007/s10147-023-02391-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K17850, KAKENHI-PROJECT-22K08890
  • [Journal Article] Axillary cutaneous metastasis of colon cancer with microsatellite instability-high and BRAF V600E mutation treated with curative-intent surgery: a case report2023

    • Author(s)
      Yamai Daisuke、Shimada Yoshifumi、Ozeki Hikaru、Matsumoto Akio、Abe Kaoru、Tajima Yosuke、Nakano Mae、Ichikawa Hiroshi、Sakata Jun、Wakai Toshifumi
    • Journal Title

      Surgical Case Reports

      Volume: 9 Issue: 1 Pages: 196-196

    • DOI

      10.1186/s40792-023-01780-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K08189, KAKENHI-PROJECT-21H02998
  • [Journal Article] 潰瘍性大腸炎術後回腸嚢炎とスフィンゴシン-1-リン酸の関連2022

    • Author(s)
      亀山仁史、永橋昌幸、田島陽介、小柳英人、廣瀬雄己、中野麻恵、中野雅人、島田能史、竹内志穂、奥田修二郎、若井俊文
    • Journal Title

      新潟医学会雑誌

      Volume: 136 Pages: 219-224

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09074
  • [Journal Article] Differential analysis of microbiomes in mucus and tissues obtained from colorectal cancer patients.2022

    • Author(s)
      Tajima Y, Okuda S, Hanai T, Hiro J, Masumori K, Koide Y, Kamiya T, Cheong Y, Inaguma G, Shimada Y, Wakai T, Takihara H, Akimoto S, Matsuoka H, Uyama I, Suda K.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Issue: 1 Pages: 18193-18193

    • DOI

      10.1038/s41598-022-21928-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Journal Article] Unveiling microbiome profiles in human inner body fluids and tumor tissues with pancreatic or biliary tract cancer.2022

    • Author(s)
      Okuda S, Hirose Y, Takihara H, Okuda A, Ling Y, Tajima Y, Shimada Y, Ichikawa H, Takizawa K, Sakata J, Wakai T.
    • Journal Title

      Sci Rep.

      Volume: 12(1) Issue: 1 Pages: 8766-8766

    • DOI

      10.1038/s41598-022-12658-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19556, KAKENHI-PROJECT-21K17850, KAKENHI-ORGANIZER-21H05107
  • [Journal Article] Histopathological characteristics and artificial intelligence for predicting tumor mutational burden-high colorectal cancer2021

    • Author(s)
      Shimada Yoshifumi、Okuda Shujiro、Watanabe Yu、Tajima Yosuke、Nagahashi Masayuki、Ichikawa Hiroshi、Nakano Masato、Sakata Jun、Takii Yasumasa、Kawasaki Takashi、Homma Kei-ichi、Kamori Tomohiro、Oki Eiji、Ling Yiwei、Takeuchi Shiho、Wakai Toshifumi
    • Journal Title

      Journal of Gastroenterology

      Volume: - Issue: 6 Pages: 547-559

    • DOI

      10.1007/s00535-021-01789-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04123, KAKENHI-PROJECT-18K08612, KAKENHI-PROJECT-21H02998, KAKENHI-PROJECT-21K17850
  • [Journal Article] RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer2020

    • Author(s)
      Matsumoto A, Shimada Y, Nakano M, Oyanagi H, Tajima Y, Nakano M, Kameyama H, Hirose Y, Ichikawa H, Nagahashi M, Nogami H, Maruyama S, Takii Y, Ling Y, Okuda S, Wakai T.
    • Journal Title

      Oncology Reports

      Volume: 43 Pages: 1853-1862

    • DOI

      10.3892/or.2020.7561

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08612, KAKENHI-PROJECT-17K10624, KAKENHI-PROJECT-19K20397
  • [Journal Article] SMAD4 alteration associates with invasive-front pathological markers and poor prognosis in colorectal cancer2019

    • Author(s)
      Oyanagi H, Shimada Y, Nagahashi M, Ichikawa H, Tajima Y, Abe K, Nakano M, Kameyama H, Takii Y, Kawasaki T, Homma KI, Ling Y, Okuda S, Takabe K, Wakai T.
    • Journal Title

      Histopathology

      Volume: 74 Issue: 6 Pages: 873-882

    • DOI

      10.1111/his.13805

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08612
  • [Journal Article] Genomic characterization of colitis-associated colorectal cancer.2018

    • Author(s)
      Kameyama H, Nagahashi M, Shimada Y, Tajima Y, Ichikawa H, Nakano M, Sakata J, Kobayashi T, Narayanan S, Takabe K, Wakai T.
    • Journal Title

      World journal of surgical oncology

      Volume: 16 Issue: 1 Pages: 121-121

    • DOI

      10.1186/s12957-018-1428-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Journal Article] Feasibility of restorative proctocolectomy in patients with ulcerative colitis-associated lower rectal cancer: A retrospective study.2018

    • Author(s)
      Hotta S, Shimada Y, Nakano M, Yamada S, Abe K, Oyanagi H, Yagi R, Tajima Y, Nakano M, Kameyama H, Nagahashi M, Sakata J, Kobayashi T, Wakai T.
    • Journal Title

      Asian Journal of Surgery

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Journal Article] メチシリン耐性黄色ブドウ球菌に対するヤスダヨーグルトの抗菌活性の検討2018

    • Author(s)
      田島陽介,立石善隆,亀山仁史,松本壮吉,若井俊文
    • Journal Title

      新潟医学会雑誌

      Volume: 131 Pages: 645-653

    • NAID

      120006763487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K21041
  • [Journal Article] Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer.2018

    • Author(s)
      Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Takabe K, Wakai T.
    • Journal Title

      Journal of surgical research

      Volume: 231 Pages: 323-330

    • DOI

      10.1016/j.jss.2018.05.085

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] 大腸癌肝転移Radiomics解析による遺伝子変異予測モデルの構築2024

    • Author(s)
      松本瑛生,中野雅人,山崎元彦,山井大介,宗岡悠介,田島陽介,島田能史,坂田 純,石川浩志、若井俊文
    • Organizer
      第79回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-22K08794
  • [Presentation] 大腸癌における細菌叢と臨床病理学的因子および予後との関連2023

    • Author(s)
      田島 陽介, 島田 能史, 中野 麻恵, 中野 雅人, 山井 大介, 阿部 馨, 松本 瑛生, 大関 瑛, 宗岡 悠介, 廣瀬 雄己, 臼井 賢司, 石川 博補, 加納 陽介, 三浦 宏平, 市川 寛, 滝沢 一泰, 小林 隆, 坂田 純, 奥田 修二郎, 若井 俊文
    • Organizer
      第123回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Presentation] Stage I-III大腸癌におけるPTEN変異の臨床的意義の検討2023

    • Author(s)
      田島陽介,島田能史,中野麻恵,阿部馨,山井大介,市川寛,三浦宏平,坂田純,小林隆,若井俊文
    • Organizer
      第78回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-22K08812
  • [Presentation] 下部直腸癌の側方領域転移症例における壁外非連続性癌進展病巣の臨床的意義2023

    • Author(s)
      山井大介、島田能史、松本瑛生、阿部馨、田島陽介、中野麻恵、中野雅人、宗岡悠介、臼井賢司、石川博補、加納陽介、市川寛、滝沢一泰、坂田純、小林隆、野上仁、丸山聡、瀧井康公、奥田修二郎、若井俊文
    • Organizer
      第123回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-22K08890
  • [Presentation] 大腸癌患者の全ゲノム解析と遺伝子パネル検査における変異シグネチャーの相関性2023

    • Author(s)
      廣瀬 雄己, 島田 能史, 田島 陽介, 安部 馨, 松本 瑛生, 大関 瑛, 土田 純子, 諸 和樹, 宗岡 悠介, 市川 寛, 竹内 志穂, 永橋 昌幸, 坂田 純, 奥田 修二郎, 若井 俊文
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Presentation] 下部直腸癌の側方領域おける壁外非連続性癌進展病巣の臨床的意義2022

    • Author(s)
      山井大介、島田能史、松本瑛生、田島陽介、中野麻恵、中野雅人、宗岡悠介、加納陽介、石川博補、三浦宏平、市川寛、羽入隆晃、滝沢一泰、石川卓、坂田純、小林隆、野上仁、丸山聡、瀧井康公、若井俊文
    • Organizer
      第20回日本消化器外科学会大会
    • Data Source
      KAKENHI-PROJECT-22K08890
  • [Presentation] ヒトの大腸癌および大腸粘膜に定着した細菌を同定する手法の検討2022

    • Author(s)
      田島陽介、廣純一郎、松岡 宏、花井 恒一、島田能史、奥田修二郎、若井俊文、須田康一
    • Organizer
      第30回日本消化器関連学会週間(JDDW2022)
    • Data Source
      KAKENHI-PROJECT-22K19556
  • [Presentation] 外科に関連した細菌の腸内細菌叢の話題2021

    • Author(s)
      田島陽介、花井恒一
    • Organizer
      消化器癌学術講演会2021
    • Data Source
      KAKENHI-PROJECT-19K18105
  • [Presentation] 慢性炎症による癌の増殖・転移を促進する脂質メディエーター分子機構2020

    • Author(s)
      永橋 昌幸, 土田 純子, 油座 築, 諸 和樹, 根本 万里子, 廣瀬 雄己, 利川 千絵, 五十嵐 麻由子, 三浦 宏平, 田島 陽介, 市川 寛, 羽入 隆晃, 滝沢 一泰, 中島 真人, 島田 能史, 小林 隆, 坂田 純, 石川 卓, 亀山 仁史, 若井 俊文
    • Organizer
      第120回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-20K09074
  • [Presentation] 大腸癌のPrecision medicineの現状と展望 大腸癌診療における遺伝子パネル検査の可能性2019

    • Author(s)
      島田 能史, 永橋 昌幸, 市川 寛, 田島 陽介, 中野 雅人, 阿部 馨, 田中 花菜, 小柳 英人, 諸 和樹, 滝沢 一泰, 羽入 隆晃, 廣瀬 雄己, 三浦 宏平, 小林 隆, 坂田 純, 亀山 仁史, 野上 仁, 丸山 聡, 瀧井 康公, 若井 俊文
    • Organizer
      第74回日本大腸肛門病学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] 大腸癌Hypermutationの臨床病理学的特徴(Clinicopathological features of hypermutation in colorectal cancer)2019

    • Author(s)
      島田 能史, 田島 陽介, 小柳 英人, 永橋 昌幸, 市川 寛, 中野 麻恵, 中野 雅人, 諸 和樹, 坂田 純, 小林 隆, 亀山 仁史, 奥田 修二郎, 若井 俊文
    • Organizer
      第78回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] 潰瘍性大腸炎関連大腸癌診断における脂質メディエーター(S1P)解析の有用性2018

    • Author(s)
      亀山仁史,永橋昌幸,油座 築,田島陽介,羽入隆晃,中野雅人,中島真人,島田能史,坂田 純,若井俊文
    • Organizer
      第73回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] High Expression of Sphingosine Kinase 1 in Colitis-Associated Cancer2018

    • Author(s)
      Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, Nakajima M, Ichikawa H, Sakata J, Kobayashi T, Takabe K, Wakai T
    • Organizer
      14th Annual Academic Surgical Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] 潰瘍性大腸炎に合併した大腸癌(colitic cancer)におけるリン酸化スフィンゴシンキナーゼ1高発現の意義2018

    • Author(s)
      油座 築、永橋昌幸、島田能史、中野麻恵、田島陽介、亀山仁史、中島真人、市川 寛、坂田 純、小林 隆、高部和明、若井俊文
    • Organizer
      第118回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K10624
  • [Presentation] ヨーグルトのMRSAに対する抗菌活性の検討2017

    • Author(s)
      田島陽介、亀山仁史、山田沙季、山本潤、堀田真之介、橋本喜文、田村博史、八木亮磨、八木寛、細井愛、岩城孝和、市川寛、岡村拓磨、木戸知紀、中野雅人、永橋昌幸、島田能史、坂田純、小林隆、若井俊文
    • Organizer
      日本外科学会
    • Data Source
      KAKENHI-PROJECT-16K21041
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