Seya Daiki 瀬谷大貴

Researcher Number	30806021
Other IDs
Affiliation (Current)	2022: 東京慈恵会医科大学, 医学部, ポストドクトラルフェロー
Affiliation (based on the past Project Information) *help	2020 – 2022: 東京慈恵会医科大学, 医学部, ポストドクトラルフェロー 2021: 国立研究開発法人国立循環器病研究センター, 研究所, 流動研究員 2017 – 2019: 国立研究開発法人国立循環器病研究センター, 研究所, 流動研究員
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Embryonic/Neonatal medicine / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 48010:Anatomy-related
Keywords	Principal Investigator 先天性心疾患 / 転写調節因子 / 発現制御 / ノックアウトマウス / 形態形成 / 発生・分化 / 心血管系 / 発生・形態形成 / 肺高血圧 / 病態モデル / 肺静脈 / 肺循環障害 … More Except Principal Investigator … More 形態形成 / シグナル伝達 / 心血管発生 / 心血管系 / 発生 / 転写調節因子 / 先天性心疾患 / ノックアウトマウス / 発生・形態形成 / 心血管発生・形態形成 / 先天性心血管疾患 / 遺伝性血管病 / 細胞シグナル伝達 / 遺伝子組換えマウス / 内皮細胞 / 心筋細胞 / 難治性血管病 / 胸部大血管 / 心筋 / 転写 / 細胞系譜 / 心室筋 / 転写制御 / Notch/Rbpjシグナル伝達経路 / 心臓 Less

遺伝子改変マウスモデルを用いた肺静脈性肺高血圧症の病態解明および新規治療法の探索Principal Investigator
- Principal Investigator
  
  瀬谷大貴
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Jikei University School of Medicine
Ventricular transcription factor cascade in the formation of atrioventricular valve and septum during embryonic heart development.Principal Investigator
- Principal Investigator
  
  Seya Daiki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Jikei University School of Medicine
  National Cardiovascular Center Research Institute
胸部大血管および心室筋形成における細胞分化の分子機構
- Principal Investigator
  
  渡邉裕介
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  National Cardiovascular Center Research Institute
Significance of cellular signaling pathways in cardiovascular development and disease
- Principal Investigator
  
  NAKAGWA Osamu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Cardiovascular Center Research Institute
Signaling pathways that regulate cardiovascular development and morphogenesis
- Principal Investigator
  
  Nakagawa Osamu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  National Cardiovascular Center Research Institute

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Sample Preparation for Computed Tomography-based Three-dimensional Visualization of Murine Hind-limb Vessels2021
- Author(s)
  Seya Daiki、Xu Yuqing、Mukunoki Toshifumi、Tsujita Kenichi、Nakagawa Osamu、Arima Yuichiro
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: -
- DOI
  10.3791/63009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17318, KAKENHI-PROJECT-18H02787
[Journal Article] A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2‐Mycn pathway during cardiac morphogenesis2021
- Author(s)
  Seya Daiki、Ihara Dai、Shirai Manabu、Kawamura Teruhisa、Watanabe Yusuke、Nakagawa Osamu
- Journal Title
  
  Dev Growth Differ.
  
  Volume: 63 Pages: 82-92
- DOI
  10.1111/dgd.12707
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17318, KAKENHI-PROJECT-18H02787, KAKENHI-PROJECT-19H03398
[Journal Article] Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription.2020
- Author(s)
  Watanabe Yusuke、Seya Daiki、Ihara Dai、Ishii Shuhei、Uemoto Taiki、Kubo Atsushi、Arai Yuji、Isomoto Yoshie、Nakano Atsushi、Abe Takaya、Shigeta Mayo、Kawamura Teruhisa、Saito Yoshihiko、Ogura Toshihiko、Nakagawa Osamu
- Journal Title
  
  J Biol Chem.
  
  Volume: 295 Pages: 17632-17645
- DOI
  10.1074/jbc.ra120.015003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17318, KAKENHI-PROJECT-18H02787, KAKENHI-PROJECT-19H03398
[Journal Article] Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors.2020
- Author(s)
  Ihara Dai、Watanabe Yusuke、Seya Daiki、Arai Yuji、Isomoto Yoshie、Nakano Atsushi、Kubo Atsushi、Ogura Toshihiko、Kawamura Teruhisa、Nakagawa Osamu
- Journal Title
  
  Developmental Biology
  
  Volume: 461 Pages: 124-131
- DOI
  10.1016/j.ydbio.2020.02.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17318, KAKENHI-ORGANIZER-15H05935, KAKENHI-PROJECT-18H02787, KAKENHI-PROJECT-19H03398, KAKENHI-WRAPUP-20H05615
[Presentation] Changes in the transcriptional profile of rat pulmonary veins before and after birth2022
- Author(s)
  瀬谷大貴、赤池徹、岩瀬晃康、栗原裕基、南沢享
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K17318
[Presentation] Transcriptional profiles of the rat pulmonary vein during a perinatal period2021
- Author(s)
  瀬谷大貴、赤池徹、南沢享
- Organizer
  第126回日本解剖学会総会・全国学術大会／第98回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K17318
[Presentation] Function and transcriptional regulation of Hey transcription factors during cardiovascular development2021
- Author(s)
  Yusuke WATANABE, Dai IHARA, Daiki SEYA, Yuki TANAKA, Yunce WANG, Teruhisa KAWAMURA, Osamu NAKAGAWA
- Organizer
  日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] 周産期におけるラット肺静脈の転写プロファイルの検討2021
- Author(s)
  瀬谷大貴、赤池徹、南沢享
- Organizer
  第6回日本肺高血圧・肺循環学会学術集会／第27回日本小児肺循環研究会
- Data Source
  KAKENHI-PROJECT-19K17318
[Presentation] Importance and transcriptional regulation of Hey2 transcription factor in embryonic ventricles2021
- Author(s)
  Yusuke WATANABE, Daiki SEYA, Dai IHARA, Yuki TANAKA, Teruhisa KAWAMURA, Osamu NAKAGAWA.
- Organizer
  第24回日本心血管内分泌代謝学会
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] 胎生期心室筋におけるHey2転写因子の機能と発現制御機構2020
- Author(s)
  渡邉裕介、瀬谷大貴、井原大、田中裕樹、川村晃久、中川修
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] Function and transcriptional regulation of Hey transcription factors during cardiovascular development2019
- Author(s)
  Yusuke WATANABE, Dai IHARA, Daiki SEYA, Yoshie ISOMOTO, Yuji ARAI, Atsushi NAKANO, Atsushi KUBO, Osamu NAKAGAWA
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] 右心室および心室中隔におけるHey2発現は心臓形態形成に必須である2019
- Author(s)
  瀬谷大貴、井原大、川村晃久、渡邉裕介、中川修
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] Hey2 expression in the right ventricle and interventricular septum is essential for cardiac morphogenesis2019
- Author(s)
  瀬谷大貴、井原大、川村晃久、渡邉裕介、中川修
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K17318
[Presentation] Function and transcriptional regulation of Hey transcription factors during cardiovascular development2019
- Author(s)
  Yusuke WATANABE, Dai IHARA, Daiki SEYA, Yoshie ISOMOTO, Yuji ARAI, Atsushi NAKANO, Atsushi KUBO, Osamu NAKAGAWA
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] GataおよびT-box因子は胎生期心室筋におけるHey2遺伝子の転写を制御する2019
- Author(s)
  井原大、渡邉裕介、瀬谷大貴、磯本祥恵、荒井勇二、中野厚史、川村晃久、中川修
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] 右心室および心室中隔におけるHey2発現は心臓形態形成に必須である2019
- Author(s)
  瀬谷大貴、井原大、川村晃久、渡邉裕介、中川修
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Significance of Hey transcription factors in endothelial cell differentiation and embryonic vascular development2019
- Author(s)
  Toru TANAKA, Norika LIU, Shoko TAMURA, Daiki SEYA, Yusuke WATANABE, Osamu NAKAGAWA
- Organizer
  NAVBO Vascular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] GataおよびT-box因子は胎生期心室筋におけるHey2遺伝子の転写を制御する2019
- Author(s)
  井原大、渡邉裕介、瀬谷大貴、磯本祥恵、荒井勇二、中野厚史、川村晃久、中川修
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Significance of Hey transcription factors in endothelial cell differentiation and embryonic vascular development2019
- Author(s)
  Toru TANAKA, Norika LIU, Shoko TAMURA, Daiki SEYA, Yusuke WATANABE, Osamu NAKAGAWA
- Organizer
  NAVBO Vascular Biology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03398
[Presentation] 心臓発生におけるHey2の心室緻密化層領域の発現制御メカニズム解明2018
- Author(s)
  Dai Ihara, Yusuke Watanabe, Daiki Seya, Yoshie Isomoto, Teruhisa Kawamura, Osamu Nakagawa
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Significance of Hey transcriptional factors in endothelial cells during cardiovascular development2018
- Author(s)
  Yusuke WATANABE, Tomoe NAKAMURA-NISHITANI, Daiki SEYA, Dai IHARA, Teruhisa KAWAMURA, Osamu NAKAGAWA
- Organizer
  日本循環器学会　第2回Basic Cardiovascular Research Conference
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Hey転写調節因子ファミリーの胎生期血管形成における細胞特異的意義の解析2018
- Author(s)
  西谷-中村友重、渡邉裕介、瀬谷大貴、田中亨、中川修
- Organizer
  第26回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Transcriptional regulation and physiological significance of BMP-ALK1 signal target genes in embryonic vascular endothelial cells2018
- Author(s)
  Osamu NAKAGAWA, Yusuke WATANABE, Yumi KINUGASA-KATAYAMA, Tomoe NAKAMURA-NISHITANI, Yukihiro HARADA, Norika Liu, Toru TANAKA, Daiki SEYA, Dai IHARA, Teruhisa KAWAMURA
- Organizer
  12th International BMP Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Significance of Hey transcriptional factors in endothelial cells during cardiovascular development2018
- Author(s)
  Yusuke WATANABE, Tomoe NAKAMURA-NISHITANI, Daiki SEYA, Dai IHARA, Teruhisa KAWAMURA, Osamu NAKAGAWA
- Organizer
  日本血管生物医学会　第16回Korea-Japan Joint Symposium
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] Significance of the Hey family of transcription factors during cardiovascular development2018
- Author(s)
  Yusuke WATANABE, Shuhei ISHII, Taiki UEMOTO, Tomoe NAKAMURA-NISHITANI, Daiki SEYA, Dai IHARA, Teruhisa KAWAMURA, Osamu NAKAGAWA
- Organizer
  International Vascular Biology Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02787
[Presentation] 胎生期血管内皮細胞におけるHey1遺伝子の発現制御機構2017
- Author(s)
  深山俊治、渡邉裕介、瀬谷大貴、井原大、荒井勇二、磯本祥恵、中川修
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15H04883
[Presentation] Significance of Hey1 transcription factor in pharyngeal arch artery formation and regulatory mechanisms of its expression during embryonic development2017
- Author(s)
  Yusuke WATANABE, Masahide FUJITA, Shuhei ISHII, Toshiharu FUKAYAMA, Dai IHARA, Daiki SEYA, Teruhisa KAWAMURA, Osamu NAKAGAWA
- Organizer
  The 8th TAKAO International Symposium on Molecular Mechanism of Cardiopulmonary Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04883
[Presentation] 胎生期血管内皮遺伝子Tmem100の心血管形成における発現制御機構2017
- Author(s)
  片山由美、冨松彩佳、渡邉裕介、久光隆、瀬谷大貴、荒井勇二、磯本祥恵、斎藤義彦、中川修
- Organizer
  第25回日本血管生物学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04883

1. Nakagawa Osamu (40283593)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. 渡邉裕介 (20562333)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
3. 田中亨 (50806065)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. 西谷友重 (50393244)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. 浦崎明宏 (40550083)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 劉孟佳 (50826922)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. LAMRI LYNDA (90883984)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 片山由美 (20570675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 深山俊治 (60779304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 久光隆 (50327946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 山岸敬幸 (40255500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岩田裕子 (80171908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 坂部正英 (00525983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田村昌子 (30849261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小柴和子 (30467005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 能丸寛子 (30885538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 原田恭弘 (70911402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 垣花優希 (40910534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 橋本大輝 (40911342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Seya Daiki 瀬谷 大貴

Research Projects

Research Products

Co-Researchers

遺伝子改変マウスモデルを用いた肺静脈性肺高血圧症の病態解明および新規治療法の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ventricular transcription factor cascade in the formation of atrioventricular valve and septum during embryonic heart development.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

胸部大血管および心室筋形成における細胞分化の分子機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Significance of cellular signaling pathways in cardiovascular development and disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Signaling pathways that regulate cardiovascular development and morphogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sample Preparation for Computed Tomography-based Three-dimensional Visualization of Murine Hind-limb Vessels2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2‐Mycn pathway during cardiac morphogenesis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Changes in the transcriptional profile of rat pulmonary veins before and after birth2022

Author(s)

Organizer

Data Source

[Presentation] Transcriptional profiles of the rat pulmonary vein during a perinatal period2021

Author(s)

Organizer

Data Source

[Presentation] Function and transcriptional regulation of Hey transcription factors during cardiovascular development2021

Author(s)

Organizer

Data Source

[Presentation] 周産期におけるラット肺静脈の転写プロファイルの検討2021

Author(s)

Organizer

Data Source

[Presentation] Importance and transcriptional regulation of Hey2 transcription factor in embryonic ventricles2021

Author(s)

Organizer

Data Source

[Presentation] 胎生期心室筋におけるHey2転写因子の機能と発現制御機構2020

Author(s)

Organizer

Data Source

[Presentation] Function and transcriptional regulation of Hey transcription factors during cardiovascular development2019

Author(s)

Seya Daiki 瀬谷大貴