Watanabe Daiki 渡邊大輝

Researcher Number	30823281
Other IDs	https://orcid.org/0000-0002-1278-3773
Affiliation (Current)	2025: 大阪体育大学, スポーツ科学部, 助手
Affiliation (based on the past Project Information) *help	2024: 大阪体育大学, スポーツ科学部, 助手 2023 – 2024: 大阪体育大学, 体育学部, 助手 2020 – 2023: 広島大学, 人間社会科学研究科(総), 助教 2022: 国立研究開発法人国立循環器病研究センター, 研究所, 上級研究員 2021: 広島大学, 人間社会科学研究科, 助教 2019: 広島大学, 総合科学研究科, 助教 2018: 電気通信大学, 大学院情報理工学研究科, UECポスドク研究員
Review Section/Research Field	Principal Investigator Basic Section 59020:Sports sciences-related / 0909:Sports sciences, physical education, health sciences, and related fields Except Principal Investigator Basic Section 59020:Sports sciences-related / Basic Section 59010:Rehabilitation science-related
Keywords	Principal Investigator 筋疲労 / 不活動 / 筋小胞体 / スキンドファイバー / 骨格筋疲労 / 活性酸素種 / 細胞内遊離Ca2+ / カルシウム漏出 / ミツグミン23 / トレーニング … More / 単一筋線維 / 筋細胞内カルシウム恒常性 / S-glutathionylation / 筋原線維 / S-gluathionylation / カルシウムイオン / 卵巣摘出 / 細胞内カルシウム / 伸張性収縮 / エストロゲン / 骨格筋 … More Except Principal Investigator 筋疲労 / 伸張性収縮 / 高強度運動 / 骨格筋 / 能動的張力 / 受動的張力 / タイチン / 神経筋電気刺激 / 運動処方 / PGC-1α / 高強度間欠的運動 / 神経－筋電気刺激 / 特発性炎症性ミオパチー / 細胞膜興奮性 / 乳酸 / 筋力低下 / 微弱電流 / 遅発性筋痛 / 張力低下 / リカバリー / 微弱電流刺激 / 筋挫傷 / 筋収縮 / イメージング / 衝撃耐性 / 粘弾性 / 微小管 / リン酸化 / Ca2+誘因性最大張力 / 筋原線維Ca2+感受性 / タイチン依存性能動的張力 / ストレッチ Less

骨格筋の適応を促す細胞内カルシウム配分機構の包括的理解Principal Investigator
- Principal Investigator
  
  渡邊大輝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Osaka University of Health and Sport Sciences
高強度運動の筋疲労耐性効果における乳酸の作用機序の解明
- Principal Investigator
  
  浜田拓
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Osaka University of Health and Sport Sciences
Is reduction in active force after eccentric contraction alleviated via suppression of passive force reduction?
- Principal Investigator
  
  和田正信
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Hiroshima University
活動量の変化に伴う骨格筋の可塑的変化のメカニズムの解明Principal Investigator
- Principal Investigator
  
  渡邊大輝
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Osaka University of Health and Sport Sciences
  National Cardiovascular Center Research Institute
橋渡し研究の推進による特発性炎症性ミオパチー克服へ向けた運動処方の基盤創出
- Principal Investigator
  
  山田崇史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Sapporo Medical University
Does increased passive force result in an increase in active force during recovery from muscle fatigue?
- Principal Investigator
  
  Wada Masanobu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Hiroshima University
Role of Microtubules in the Muscle Structure-Contraction Relationship
- Principal Investigator
  
  Kobayashi Takuya
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Juntendo University
Does Microcurrent Electorical Neuromuscler Stimulation Improve Muscle Function after Eccentric Contraction-induced Muscle Damage in Human Skeletal Muscle
- Principal Investigator
  
  Hiroshige Yosuke
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Teikyo University
  International Pacific University
Identification of novel compound for alleviating skeletal muscle fatigue focusing on S-glutathionylationPrincipal Investigator
- Principal Investigator
  
  Watanabe Daiki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Hiroshima University
Why female has greater resistance for skeletal muscle damage than male?: contribution of mitochondriaPrincipal Investigator
- Principal Investigator
  
  Watanabe Daiki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0909:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Hiroshima University
  The University of Electro-Communications

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Ca2+ storage function is altered in the sarcoplasmic reticulum of skeletal muscle lacking mitsugumin 232024
- Author(s)
 Watanabe Daiki、Nishi Miyuki、Liu Feng、Bian Yuhan、Takeshima Hiroshi
- Journal Title
 
 American Journal of Physiology-Cell Physiology
 
 Volume: 326 Issue: 3 Pages: C795-C809
- DOI
 10.1152/ajpcell.00440.2023
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-23K10634, KAKENHI-PROJECT-21H02663, KAKENHI-PROJECT-23K24738
[Journal Article] Intrinsic contractile dysfunction due to impaired sarcoplasmic reticulum Ca2+ release in compensatory hypertrophied muscle fibers following synergist ablation2023
- Author(s)
 Tokuda Nao、Watanabe Daiki、Naito Azuma、Yamauchi Nao、Ashida Yuki、Cheng Arthur J.、Yamada Takashi
- Journal Title
 
 American Journal of Physiology-Cell Physiology
 
 Volume: 325 Issue: 3 Pages: C599-C612
- DOI
 10.1152/ajpcell.00127.2023
- Peer Reviewed / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-21K19723, KAKENHI-PROJECT-23K21587
[Journal Article] How to evaluate skeletal muscle function: suggestion from studies on skeletal muscle fatigue2022
- Author(s)
  Watanabe Daiki、Kanzaki Keita、Wada Masanobu
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 157 Issue: 1 Pages: 9-14
- DOI
  10.1254/fpj.21065
- NAID
  130008138780
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K19570
[Journal Article] Eccentric muscle contraction potentiates titin stiffness-related contractile properties in rat fast-twitch muscles2022
- Author(s)
  Shi J, Watanabe D, Wada M
- Journal Title
  
  Journal of Applied Physiology
  
  Volume: 133 Issue: 3 Pages: 710-720
- DOI
  10.1152/japplphysiol.00327.2022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11335
[Journal Article] Stretching Ameliorates Skeletal Muscle Hypoexcitability during the Early Stage of Denervation2021
- Author(s)
  芦田雪、渡邊大輝、宮田浩文、檜森弘一、玉井勝是、木村伊織、阿部真佐美、今井富裕、山田崇史
- Journal Title
  
  Journal of Physical Therapy Fundamentals
  
  Volume: 24 Issue: 1 Pages: 1-10
- DOI
  10.24780/jjptf.24.1_1
- NAID
  130008113500
- ISSN
  2436-6382
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19J22784, KAKENHI-PROJECT-21K19723, KAKENHI-PROJECT-23K21587
[Journal Article] Effects of vigorous isometric muscle contraction on titin stiffness-related contractile properties in rat fast-twitch muscles2021
- Author(s)
  Shi, J., Watanabe, D. and Wada, M.
- Journal Title
  
  American Journal of Physiology
  
  Volume: 321 Issue: 6 Pages: R858-R868
- DOI
  10.1152/ajpregu.00189.2021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11335
[Journal Article] Orthograde signal of dihydropyridine receptor increases Ca2+ leakage after repeated contractions in rat fast-twitch muscles in vivo2021
- Author(s)
  Watanabe Daiki、Wada Masanobu
- Journal Title
  
  American Journal of Physiology-Cell Physiology
  
  Volume: - Issue: 5 Pages: C806-C821
- DOI
  10.1152/ajpcell.00364.2020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K19570
[Journal Article] Sex differences in mitochondrial Ca2+ handling in mouse fast-twitch skeletal muscle in vivo2020
- Author(s)
  Watanabe Daiki、Hatakeyama Koji、Ikegami Ryo、Eshima Hiroaki、Yagishita Kazuyoshi、Poole David C.、Kano Yutaka
- Journal Title
  
  Journal of Applied Physiology
  
  Volume: 128 Issue: 2 Pages: 241-251
- DOI
  10.1152/japplphysiol.00230.2019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03240, KAKENHI-PROJECT-19K21491
[Journal Article] Fatigue‐induced change in T‐system excitability and its major cause in rat fast‐twitch skeletal muscle in vivo2020
- Author(s)
  Watanabe Daiki、Wada Masanobu
- Journal Title
  
  The Journal of Physiology
  
  Volume: 598 Issue: 22 Pages: 5195-5211
- DOI
  10.1113/jp279574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K19570
[Journal Article] Effects of clenbuterol administration on mitochondrial morphology and its regulatory proteins in rat skeletal muscle2019
- Author(s)
  Yu Kitaoka, Daiki Watanabe, Yudai Nonaka, Kazuyoshi Yagishita, Yutaka Kano, Daisuke Hoshino
- Journal Title
  
  Physiological Reports
  
  Volume: 7 Issue: 19
- DOI
  10.14814/phy2.14266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17792, KAKENHI-PROJECT-19K21491
[Presentation] 不活動に伴う筋原線維の収縮特性および受動的張力の経時的変化2024
- Author(s)
  渡邊大輝，松本真里，三島隆章，浜田拓
- Organizer
  第62回大阪体育学会
- Data Source
  KAKENHI-PROJECT-23K24738
[Presentation] 神経筋接合部の伝達阻害が摘出骨格筋の興奮性に及ぼす影響2024
- Author(s)
  31.松本真里，浜田拓，三島隆章，渡邊大輝
- Organizer
  第62回大阪体育学会
- Data Source
  KAKENHI-PROJECT-23K24738
[Presentation] Role of Mitsugumin 23 in Ca2+ storage of sarcoplasmic reticulum in type I and type II fibers of the mice2023
- Author(s)
 Watanabe Daiki、Nishi Miyuki、Liu Feng、Takeshima Hiroshi
- Organizer
 50th European Muscle Conference
- Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-23K24738
[Presentation] 協働筋切除により筋機能は低下する2023
- Author(s)
  德田奈央，渡邊大輝，内藤雷，山内菜緒，芦田雪，山田崇史
- Organizer
  第9回骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-23K21587
[Presentation] 協働筋切除による筋肥大モデルにおける興奮収縮連関障害のメカニズム2023
- Author(s)
  德田奈央，渡邊大輝，内藤雷，山内菜緒，木村伊織，芦田雪，山田崇史
- Organizer
  第9回日本筋学会学術大会・第10回筋ジストロフィー医療研究会
- Data Source
  KAKENHI-PROJECT-23K21587
[Presentation] The effects of eccentric muscle contraction on titin stiffness-related contractile properties in rat fast-twitch muscles2023
- Author(s)
  Shi, J., Watanabe, D., and Wada, M.
- Organizer
  52nd European Muscle Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K10714
[Presentation] 代償性過負荷による筋線維の肥大は興奮収縮連関障害を伴う2023
- Author(s)
  德田奈央，渡邊大輝，山田崇史
- Organizer
  第31回日本運動生理学会大会
- Data Source
  KAKENHI-PROJECT-23K21587
[Presentation] Compensatory hypertrophied muscle fibers display intrinsic contractile dysfunction due to impaired sarcoplasmic reticulum Ca2+ release.2023
- Author(s)
  Tokuda N, Watanabe D, Naito A, Yamauchi N, Ashida Y, Yamada T
- Organizer
  50th European Muscle Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21587
[Presentation] Contribution of Mitsugumin 23 to Ca2+ leakage of sarcoplasmic reticulum in skeletal muscle fibers2023
- Author(s)
 Watanabe Daiki、Nishi Miyuki、Liu Feng、Takeshima Hiroshi
- Organizer
 Gordon Research Conference Muscle: Excitation-contraction coupling
- Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-23K24738
[Presentation] 高強度インターバル運動が筋疲労に及ぼす影響2022
- Author(s)
  和田正信，渡邊大輝
- Organizer
  第77回日本体力医学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24738
[Presentation] ミツグミン23が骨格筋疲労に及ぼす影響2022
- Author(s)
  渡邊大輝，西美幸，竹島浩
- Organizer
  第8回日本筋学会
- Data Source
  KAKENHI-PROJECT-23K24738
[Presentation] 協働筋切除による筋肥大モデルにおける収縮機能障害2022
- Author(s)
  德田奈央，渡邊大輝，内藤雷，山内菜緒，木村伊織，芦田雪，山田崇史
- Organizer
  第77回日本体力医学会大会
- Data Source
  KAKENHI-PROJECT-23K21587
[Presentation] 高強度インターバルトレーニングに伴う骨格筋の適応メカニズム2022
- Author(s)
  渡邊大輝
- Organizer
  第77回日本体力医学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24738
[Presentation] オーバートレーニングによる筋機能障害のメカニズム2022
- Author(s)
  德田奈央，渡邊大輝，内藤雷，山内菜緒，木村伊織，芦田雪，山田崇史
- Organizer
  第27回日本基礎理学療法学会学術大会
- Data Source
  KAKENHI-PROJECT-23K21587
[Presentation] 協働筋切除による筋線維の肥大は収縮機能の低下を伴う2021
- Author(s)
  德田奈央，渡邊大輝，芦田雪，木村伊織，内藤雷，山内菜緒，山田崇史
- Organizer
  第7回日本筋学会学術大会
- Data Source
  KAKENHI-PROJECT-23K21587
[Presentation] Intrinsic contractile dysfunction in a surgical model of muscle hypertrophy2021
- Author(s)
  Tokuda N, Watanabe D, Ashida Y, Kimura I, Naito A, Yamauchi N, Yamada T
- Organizer
  Journal of General Physiology Symposium, E-C coupling meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21587
[Presentation] Microcurrent electrical neuromuscular stimulation promotes muscle fatigue and soreness recovery after eccentric contraction: double-blind, randomized controlled trial.2021
- Author(s)
  HIROSHIGE Y, SAWAI A, KAMIKUBO T, YAMAGUCHI R, TANAKA K, WATANABE D, WADA M
- Organizer
  European College of Sports Science Congress 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11406
[Presentation] 伸張性収縮に伴う筋細胞内小器官の機能変化2021
- Author(s)
  渡邊大輝
- Organizer
  第28回日本運動生理学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K19570
[Presentation] 生体で骨格筋収縮力が変化した原因を明らかにするために：in vivo収縮とメカニカルスキンドファイバーの融合2021
- Author(s)
  渡邊大輝，和田正信
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-20K19570
[Presentation] 持続的なストレッチは脱神経筋におけるクロナキシー増大を抑制する2021
- Author(s)
  芦田雪，渡邊大輝，宮田浩文，檜森弘一，玉井勝是，木村伊織，阿部真佐美，山田崇史
- Organizer
  第26回日本基礎理学療法学会学術大会
- Data Source
  KAKENHI-PROJECT-23K21587
[Presentation] Sex differences in prolonged low-frequency force depression after eccentric contractions2019
- Author(s)
  Daiki Watanabe, Ryo Ikegami, Yutaka Kano
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21491
[Presentation] Sex differences in prolonged low-frequency force depression after eccentric contractions2019
- Author(s)
  Watanabe, D., Ikegami, R., Kano, Y.
- Organizer
  Gordon Research Conference Muscle: Excitation-Contraction Coupling
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21491
[Presentation] Sex difference in mitochondria Ca2+ handling properties in mouse skeletal muscle2019
- Author(s)
  Daiki Watanabe, Hatakeyama Koji, Ikegami Ryo, Eshima Hiroaki, Yutaka Kano
- Organizer
  Federation of the Asian and Oceanian Physiological Societies Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21491
[Presentation] Sex differences in mitochondria Ca2+ handling properties in mouse skeletal muscle2019
- Author(s)
  Watanabe, D., Hatakeyama, K., Ikegami, R., Eshima, H., Kano, Y.
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21491

1. Wada Masanobu (80220961)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. 松永智 (70221588)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Kobayashi Takuya (60468585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Hiroshige Yosuke (10803695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 矢中規之 (70346526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 茅元司 (00422098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 呉林なごみ (50133335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 浜田拓 (00466294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山田崇史 (50583176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
10. 西美幸 (60183894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 竹島浩 (70212024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. HOSHINO Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 竹島美幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
14. 狩野豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Daiki 渡邊 大輝

Research Projects

Research Products

Co-Researchers

骨格筋の適応を促す細胞内カルシウム配分機構の包括的理解Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高強度運動の筋疲労耐性効果における乳酸の作用機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Is reduction in active force after eccentric contraction alleviated via suppression of passive force reduction?

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

活動量の変化に伴う骨格筋の可塑的変化のメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

橋渡し研究の推進による特発性炎症性ミオパチー克服へ向けた運動処方の基盤創出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Does increased passive force result in an increase in active force during recovery from muscle fatigue?

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of Microtubules in the Muscle Structure-Contraction Relationship

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Does Microcurrent Electorical Neuromuscler Stimulation Improve Muscle Function after Eccentric Contraction-induced Muscle Damage in Human Skeletal Muscle

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel compound for alleviating skeletal muscle fatigue focusing on S-glutathionylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Why female has greater resistance for skeletal muscle damage than male?: contribution of mitochondriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Ca<sup>2+</sup> storage function is altered in the sarcoplasmic reticulum of skeletal muscle lacking mitsugumin 232024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intrinsic contractile dysfunction due to impaired sarcoplasmic reticulum Ca<sup>2+</sup> release in compensatory hypertrophied muscle fibers following synergist ablation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] How to evaluate skeletal muscle function: suggestion from studies on skeletal muscle fatigue2022

Author(s)

Journal Title

DOI

NAID

ISSN

Watanabe Daiki 渡邊大輝