INOUE Tan 井上丹

Researcher Number	40114855
Other IDs
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Affiliation (based on the past Project Information) *help	2015: 京都大学, 大学院生命科学研究科, 教授 2011 – 2014: 京都大学, 生命科学研究科, 教授 2006: Kyoto University, Graduate School of Biostudies, Professor 2005 – 2006: 京都大学, 生命科学研究科, 教授 2003 – 2004: 京都大学, 大学院・生命科学研究科, 教授 … More 2002: 京都大学, 生命科学研究科, 教授 2001: Kyoto University, Graduate School of Science, Professor, 大学院・理学研究科, 教授 1999 – 2001: 京都大学, 大学院・生命科学研究科, 教授 1995 – 1998: 京都大学, 大学院・理学研究科, 教授 1996: Kyoto University, Chemistry, Professor, 大学院理学研究科, 教授 1993 – 1994: 京都大学, 理学部, 教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Molecular biology / Chemical biology / Structural biochemistry Except Principal Investigator Complex systems / Developmental biology / Structural biochemistry
Keywords	Principal Investigator RNA / リボザイム / 酵素 / RNP / ribozyme / 分子デザイン / in vitro selection / synthetic biology / 触媒部位 / 立体構造 … More / P4-P6 RNA / 分子エンジニアリング / ナノバイオ / リガーゼ / in vitroセレクション / テトラヒメナ / nano / molccular engineering / molecular design / ligase / in vitro セレクション / self-foldingRNA / ナオバイオ / self-folding RNA / 核酸 / 遺伝子 / 分子認識 / ナノ / splicing / hammerhead ribozyme / group I introns / snRNA / catakytic RNA / catalyticRNA / スプライシング / 反応機構 / 分子設計 / 23SリボソームRNA / RNase P / U6snRNA / マキシザイム / GNRA-receptor 4 / G167 / ンマーヘッド型リボザイム / ヘアピン型リボザイム / スプライソソーム / リボソーム / snRNP / ハンマーヘッド型リボザイム / グループIイントロン / Tetrahymena / enzyme / 分子進化 / バイオナノテクノロジー / シンセティックバイオロジー / コンビナトリアル / 分子生物学 … More Except Principal Investigator NMR / tRNA / リボザイム / ミトコンドリア / RNA結合蛋白質 / スプライシング / RNA / 高次生命現象 / 触媒機能 / RNA動的機能 / Mitochondria / Aplicing / Translation Factors / Rybozyme / RNA High-level Function / RNA Information Function / RNA Catalytic Function / 高次生命現像 / PNAの触媒機能 / 動的構造の解析法 / ミトコンドリア病 / RNAの高次構造 / 分子擬態 / mRNAの発現調節 / RNAの触媒機能 / 高次機能 / 情報機能 / 翻訳因子 / RNA高次機能 / RNA情報機能 / RNA触媒機能 / Biosensor / Protein interaction / Gene targeting / Higher plants / Morphogenesis / Cre-loxP / Fission yeast / 植物 / 胚形成 / 蛋白高次機能構造 / 遺伝子ターゲティング / RNAプロセシング / バイオモニタリング / DNA再複製 / 細胞周期 / 温度感受性突然変異体 / ATPase / 免疫病 / 免疫系 / バイオセンサー / 分子相互作用 / 遺伝子標的 / 高等植物 / 形態形成 / Cre-IoxP / 分裂酵母 / sx1 protein / stable isotope labeling / base pairing / modified nucleoside / alternative splicing / splicing / ミトコンドリアtRNA / mRNAスプライシング / rRNA / nRNAスプライシング / 機能構造 / 蛋白質 / 安定同位体標識 / 塩基対合 / 修飾ヌクレオシド / オルタナテイブスプライシング / 信号伝達制御 / nanobio technology / ＲＮＡ / 遺伝暗号 / 数理モデル / タンパク質 / 進化分子工学 / 合成生物学 / プロテイン・キナーゼ / 突然変異体 / 多細胞生物 / プロテインキナーゼ / 生殖細胞 / 体細胞 / ボルボックス / RNA-蛋白質複合体 / SELEX法 / 構造-機能相関 / mRNA動的構造 / 情報発現調節機能 Less

Evolutionary engineering of biomacromolecules for improvement of artificial genetic circuits
- Principal Investigator
  
  Kiga Daisuke
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Institute of Technology
Design and construction of new systems for regulating human cell fatePrincipal Investigator
- Principal Investigator
  
  INOUE Tan
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Chemical biology
- Research Institution
  Kyoto University
RNAバイオナノサイエンスの基礎研究Principal Investigator
- Principal Investigator
  
  井上丹
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Network of functions and structures of ribozymesPrincipal Investigator
- Principal Investigator
  
  INOUE Tan
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecular Basis for RNA Dynamic Function
- Principal Investigator
  
  WATANABE Kimitsuna
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
Researches on ribozymes at molecular and atomic levelPrincipal Investigator
- Principal Investigator
  
  INOUE Tan
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
超分子リボザイムの機能発現の研究Principal Investigator
- Principal Investigator
  
  井上丹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
RNA機能のフロンティア
- Principal Investigator
  
  WATANABE Kimitsuna
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
ボルボックスを用いた多細胞体制構築機構の分子遺伝学的研究
- Principal Investigator
  
  SHIRAISHI Hideaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Developmental biology
- Research Institution
  Kyoto University
超分子リボザイムの機能発現の研究Principal Investigator
- Principal Investigator
  
  井上丹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Experimental simulation on molecular evolution of RNA enzymes (ribozymes)Principal Investigator
- Principal Investigator
  
  INOUE Tan
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  KYOTO UNIVERSITY
Regulation of Gene Expression
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Mechanism of RNA function expression
- Principal Investigator
  
  WATANABE Kimitsuna
- Project Period (FY)
  1992 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo

All 2016 2015 2014 2013 2012 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] Nucleic Acid Switches and Sensors (edited by Scott K.Silverman)2006
- Author(s)
  Tan Inoue*, Yoshiya Ikawa
- Total Pages
  12
- Publisher
  Eurekah. com and Springer Science+Business Media
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] A Bacterial Continuous Culture System Based on a Microfluidic Droplet Open Reactor2016
- Author(s)
  Manami Ito,Haruka Sugiura, Shotaro Ayukawa, Daisuke Kiga,Masahiro Takinoue
- Journal Title
  
  Anal. Sci.
  
  Volume: 32 Issue: 1 Pages: 61-66
- DOI
  10.2116/analsci.32.61
- NAID
  130005118567
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26540150, KAKENHI-PROJECT-25730176, KAKENHI-PLANNED-23119005, KAKENHI-PROJECT-26540152
[Journal Article] A purification method for a molecular complex in which a scaffold molecule is fully loaded with heterogeneous molecules2015
- Author(s)
  Shoji Ohuchi, Fumihiko Sagawa, Tan Inoue
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 3 Pages: e0120576-e0120576
- DOI
  10.1371/journal.pone.0120576
- NAID
  120005615650
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23221011, KAKENHI-PLANNED-23119005
[Journal Article] A trifunctional, triangular RNA-protein complex2015
- Author(s)
  Shoji Ohuchi, Fumihiko Sagawa, Tan Inoue
- Journal Title
  
  FEBS letters
  
  Volume: x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23221011
[Journal Article] Stereo-specific azimuth adjustment of a protein at the tip of an RNA using the circular permutation technique2015
- Author(s)
  Shoji Ohuchi, Fumihiko Sagawa, Tan Inoue
- Journal Title
  
  ACS nano letter
  
  Volume: x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23221011
[Journal Article] Designed regular tetragon-shaped RNA-protein complexes with RPL1 for bionanotechnology and synthetic biology2015
- Author(s)
  Hirohisa Ohno, Tan Inoue
- Journal Title
  
  ACS nano
  
  Volume: x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23221011
[Journal Article] Cell-surface receptor control that depends on the size of a synthetic equilateral-triangular RNA-protein complex2014
- Author(s)
  1.Yoshihiko Fujita, Tan Inoue
- Journal Title
  
  Sci. Rep.
  
  Volume: 4 Issue: 1 Pages: 1-7
- DOI
  10.1038/srep06422
- NAID
  120005575182
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23221011, KAKENHI-PLANNED-23119005
[Journal Article] Directed evolution of a synthetic RNA-protein module to create a new translational switch2013
- Author(s)
  Tomoaki Hara, Hirohide Saito and Tan Inoue
- Journal Title
  
  Chem. Commun.
  
  Volume: Epub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23221011
[Journal Article] Feedback Control of Protein Expression in Mammalian Cells by Tunable Synthetic Translational Inhibition2012
- Author(s)
  James A. Stapleton, Kei Endo, Yoshihiko Fujita, Karin Hayashi, Masahiro Takinoue, Hirohide Saito, and Tan Inoue
- Journal Title
  
  ACS Synthetic Biology
  
  Volume: 1 Pages: 83-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23221011
[Journal Article] Self-replication reactions dependent on tertiary interaction motifs in an RNA ligase ribozyme.2012
- Author(s)
  Ohmori R, Saito H, Ikawa Y, Fujita Y, Inoue T.
- Journal Title
  
  J. Mol. Evol.
  
  Volume: 73 Pages: 221-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23221011
[Journal Article] Three-dimensionally designed protein-responsive RNA devices for cell signaling regulation2012
- Author(s)
  Shunnichi Kashida, Tan Inoue and Hirohide Saito
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 40 Pages: 9369-9378
- NAID
  120004920410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23221011
[Journal Article] The role of peptide motifs in the evolution of a protein network.2007
- Author(s)
  Saito H, Kashida S, Inoue T, Shiba K.
- Journal Title
  
  Nucleic Acids Res. 35
  
  Pages: 6357-6366
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] RNA and RNP as new molecular parts in synthetic biology・2007
- Author(s)
  Saito H, Inoue T.
- Journal Title
  
  J Biotechnol. 132
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] Structural and biochemical characterization of DSL ribozyme2006
- Author(s)
  Souta Horie, Yoshiya Ikawa, Tan Inoue
- Journal Title
  
  Biochemical and Biophysical Research Communications 339
  
  Pages: 115-121
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] Structural and Biochemical Characterization of DSL Ribozyme2006
- Author(s)
  Horie, S. Ikawa, Y. & Inoue, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 339
  
  Pages: 115-121
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] Redesign of an Artificial Ligase Ribozyme Based on the Analysis of Its Structural Elements2005
- Author(s)
  Yoshiya Ikawa, Junko Matsumoto, Souta Horie, Tan Inoue
- Journal Title
  
  RNA biology 2・4
  
  Pages: 137-142
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] A ligase ribozyme obtained from a structural pool2004
- Author(s)
  Yoshioka, Y., Ikawa, Y., Jaeger, L., Inoue, T.
- Journal Title
  
  Nucleic Acids res.Symp.Ser. 48
  
  Pages: 209-210
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] De novo synthesis and development of an RNA enzyme2004
- Author(s)
  Ikawa, Y., Tsuda, K., Matsumura, S., Inoue T.
- Journal Title
  
  Proc.Nad.Acad.Sci.USA 101
  
  Pages: 13750-13755
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] リボザイムの分子設計法-RNA構造情報の分子デザインへの還元2004
- Author(s)
  井上丹, 井川善也
- Journal Title
  
  実験医学(増刊) 22
  
  Pages: 2401-2407
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] Generation of a catalytic module on a self folding RNA2004
- Author(s)
  Yoshioka, W., Ikawa, Y., Jaeger, L., Shiraishi, H., Inoue, T.
- Journal Title
  
  RNA 10
  
  Pages: 1900-1906
- Data Source
  KAKENHI-PROJECT-14035224
[Journal Article] Artificial Modules for Enhancing Rate Constants of a Group I Intron Ribozyme without a P4-P6 Core Element2004
- Author(s)
  Shoji J.Ohuchi, Yoshiya Ikawa, Hideaki Shiraishi, Tan Inoue
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 540-546
- Data Source
  KAKENHI-PROJECT-14035224
[Presentation] RNAシンセティックバイオロジー2007
- Author(s)
  井上丹
- Organizer
  BMB 2007 第30回日本分子生物学会・第80回日本生化学会
- Place of Presentation
  パシフイコ横浜・ヨコハマグランドインクーコンチネンタルホテル
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035224

1. WATANABE Kimitsuna (00134502)

# of Collaborated Projects: 3 results

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2. YOKOYAMA Shigeyuki (00159229)

# of Collaborated Projects: 3 results

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3. SHIRAISHI Hideaki (90202118)

# of Collaborated Projects: 3 results

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4. SHIMURA Yoshiro (60025426)

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5. SHIMAMOTO Nobuo (20127658)

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6. SAITO Hirohide (20423014)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. OHTA Shigeo (00125832)

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8. NAKAMURA Yoshikazu (40114590)

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9. OHNO Mutsuhito (80201979)

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10. 坂本博 (00187048)

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11. Kiga Daisuke (30376587)

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12. IKAWA Yoshiya (70281087)

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13. KIGAWA Takanori (20270598)

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14. NISHIKAWA Kazuya (60109262)

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15. TANIGUCHI Masaru (80110310)

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16. KYO Masaharu (70195395)

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17. WATANABE Masao (90240522)

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18. OKADA Kiyotaka (50101093)

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19. KOMEDA Yoshifumi (10124215)

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20. KATO Koichi (20211849)

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21. MURAKAMI Yuji (70272995)

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22. YOSHIDA Minoru (80191617)

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23. ISOGAI Akira (20011992)

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24. KAMADA Hiroshi (00169608)

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25. WAKASUGI Hiro (10112632)

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26. SASAZUKI Takehiko (50014121)

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27. KISHIMOTO Tadamitsu (10093402)

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28. OKUMURA Ko (50009700)

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29. SHINOZAKI Kazuo (20124216)

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30. FUJII Tadashi (20011611)

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31. YAMADA Tetsuji (00191320)

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32. DOKE Noriyuki (80023472)

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33. TANAKA Keiji (10108871)

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34. SAKAI Shingo (60033388)

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36. SHIMADA Kazuo (70196476)

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37. HORINOUCHI Sueharu (80143410)

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38. MATSUBARA Ken-ichi (20037394)

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39. YAMADA Yasuyuki (50026415)

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40. KARUBE Isao (50089827)

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41. BEPPU Teruhiko (80011873)

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42. KIKUTANI Hitoshi (80161412)

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43. KOSEKI Haruhiko (40225446)

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44. SAITO Takashi (50205655)

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45. WATANABE Takeshi (40028684)

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46. TANI Tokio (80197516)

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47. TAIRA Kazunari (10261778)

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48. SAKAMOTO Kensaku (50240685)

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49. SUZUKI Tsutomu (20292782)

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75. 原知明

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78. マリセン B.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
79. バーリング R.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
80. マティス D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
81. ベノワ C.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
82. クーパー J.A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
83. ハーガン I.M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
84. ラジャウスキー K.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
85. シラー F.W.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
86. デュマ C.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
87. ツジイ F.I.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
88. ロバーツ G.C.K.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
89. デルセニー M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
90. フォルセン K.S.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
91. TSUJI Federick

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
92. FORSEN Karl

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
93. COOPER Jonathan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
94. HAGAN Iain

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
95. ROBERTS Gordon

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
96. NAKASEKO Nobuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
97. DUMAS C.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
98. SCHELLER Frieder

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
99. DELSENY Michel

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
100. MATHIS Diane

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
101. BENOIST Christophe

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
102. MALISSEN Bernard

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
103. BALLING Rudolf

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
104. RAJEWSKY Klaus

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
105. 和田雅人

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
106. スレイマン C.W.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
107. ラスキー R.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
108. シュミット R.D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
109. マリッセン B.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
110. 藤田至彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

INOUE Tan 井上 丹

Research Projects

Research Products

Co-Researchers

Evolutionary engineering of biomacromolecules for improvement of artificial genetic circuits

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Design and construction of new systems for regulating human cell fatePrincipal Investigator

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RNAバイオナノサイエンスの基礎研究Principal Investigator

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Network of functions and structures of ribozymesPrincipal Investigator

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Molecular Basis for RNA Dynamic Function

Principal Investigator

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Researches on ribozymes at molecular and atomic levelPrincipal Investigator

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超分子リボザイムの機能発現の研究Principal Investigator

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RNA機能のフロンティア

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ボルボックスを用いた多細胞体制構築機構の分子遺伝学的研究

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超分子リボザイムの機能発現の研究Principal Investigator

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Experimental simulation on molecular evolution of RNA enzymes (ribozymes)Principal Investigator

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Regulation of Gene Expression

Principal Investigator

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Mechanism of RNA function expression

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[Book] Nucleic Acid Switches and Sensors (edited by Scott K.Silverman)2006

Author(s)

Total Pages

Publisher

INOUE Tan 井上丹