Shimoya Kouichirou 下屋浩一郎

… Alternative Names

SHIMOYA Kouichiro 下屋浩一郎

SIMOYA Kouichirou 下屋浩一郎

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Researcher Number	40291950
Other IDs
External Links
Affiliation (Current)	2025: 川崎医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 川崎医科大学, 医学部, 教授 2007 – 2019: 川崎医科大学, 医学部, 教授 2006: Kawasaki Medical College, Professor, 産婦人科, 教授 2001 – 2005: 大阪大学, 医学系研究科, 助手 2002: 大阪大学, 医学系研究科, 助教授 … More 1999: Osaka University Graduate School of Medicine Assistant Professor retire, 医学系研究科, 助手 1998: 阪大, 医学部, 助手 1997 – 1998: Osaka University Medical School, Assistant Professor, 医学部, 助手 1993: Osaka Univ. Med. School Dept. of Obstet. and Gyne. Research Fellow, 医学部・附属病院, 医員 Less
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Bioethics
Keywords	Principal Investigator サイトカイン / Fractalkine / 母体ストレス / CX3CR1 / Fallopian tube / 卵管 / SNRPN / H19 / IGF2 / 卵胞 … More / 酸化ストレス / fractalkine / 子宮内感染 / 早産 / 卵巣顆粒膜細胞 / 生殖医療 / 顆粒膜細胞 / 体外受精-胚移植 / 精漿 / 線維芽細胞 / 精子機能 / ヒストン脱アセチル化酵素阻害剤 / 顆粒膜細胞腫 / 胎児脳障害 / 神経前駆細胞 / 脳性麻痺 / 新生児脳障害 / 大脳6層構造 / 脳障害 / amnion / S100B / Prostaglandin F2alpha knockout mouse / intrauterine fetal death (IUFD) / oligohydrammios / S100蛋白 / アクアポリン / 子宮内胎児発育不全 / 胎児死亡 / 羊膜 / S100B蛋白 / Prostaglandin F2alphaノックアウトマウス / 羊水過少 / 原因不明胎児死亡 / sperm / endometrium / chemokine / endometriosis / ascites / Erythropoietin / 精子 / 子宮頚 / ケモカイン受容体 / 子宮頚管 / 子宮内膜 / 腹水 / 子宮内膜症 / フラクタルカイン / ケモカイン / fraclalkine / acrosome reaction / SLPI / protease inhibitor / SLPI(secretory leukocyte elastase inhibitor) / 精子先体反応 / SLPI (secretory leukocyte elastase inhibitor) / プロテアーゼインヒビター / ovarian choriocarcinoma / human imprinted genes / genomic imprinting / IGF2.H19.SNRPN遺伝子 / HLA-G遺伝子 / ゲノム・インプリント解除 / 胚細胞系腫瘍 / 絨毛癌 / HI9 / 絨毛癌再 / 良性卵巣奇形腫 / ゲノムインプリンティング / 抗酸化力 / コルチゾール / ストレスマーカー / 嗅覚 / 子宮収縮 / 子宮筋 / 炎症 / CRP / RCAS1 / 唾液中ストレスマーカー / RCASI / 妊娠高血圧症候群 / 体外受精・胚移植 / 6 Ckine / 子宮内感染(絨毛羊膜炎) / 着床 / 6Ckine … More Except Principal Investigator 子宮内膜 / リンパ節転移 / 着床 / がん関連線維芽細胞 / endometrium / 婦人科がん / 不均一性 / stat-3 / decoy / デコイ / hypercapnia / IL-18 / COX-2 / HNE / 酸化ストレス / CD46 / dysplasia / 絨毛細胞 / 子宮頸癌 / がんの微小環境 / 着床不全 / 遺伝子導入 / 腹膜播種 / 膜タンパク質 / 蛍光イメージ / ヌードマウス皮下移植 / 子宮頸がん / 転移 / IVF-ET / decidualization / progesterone / transient in vivo gene transfer / implantation failure / 原因不明妊娠 / HVJ-E / Stat-3 / 体外受精-胚移植 / 退学受精-胚移植 / 脱落膜化 / プロゲステロン / start-3 / 一過性遺伝子導入 / NF-κB / HVJ-E vector / in vivo gene transfer / implantation / NFkappaβ / 生体内一過性遺伝子導入・発現系 / NFKappaB / 一過性強制発現 / NF KappaB / HVJ-Eベクター / neurogenesis / hypothermia / hypoxia-ischemia (HI) brain injury / cDNAマイクロアレイ / IL-10 / 低酸素虚血脳障害モデル / 低酸素虚血脳障害 / 神経幹細胞 / real time PCR / 低酸素虚血性脳症 / ステロイド / ステロイド療法 / 高二酸化炭素状態 / 低体温療法 / 新生児低酸素虚血性脳障害 / lipid peroxide catabolite / cyclin / cell cycle, cyclin / oxidative stress / preeclampsia of pregnancy / trophoblasts / サイクリン依存性キナーゼインヒビター / サイクリン依存性キナーゼ / 過酸化脂質分解産物 / サイクリン / 細胞周期 / 妊娠中毒症 / transcription / chorioamnionitis / uterine contraction / methylated DNA / preterm labor / oxytocin receptor / HNE(4-hysroxy-2-nonenal) / prostaglandin / COX(cyclooxygenase) / HNE(4-hydroxy-2-nonenal) / シクロオキシゲナーゼ / ホスホリパーゼ / アラキドン酸 / oviduct / prostaglandin D synthetase (PGDS) / oestrogen / 受精 / プロスタグランディン / プロスタグランディンD合成酵素 / 女性ホルモン / 卵管 / ポロスタグランディンD合成酵素 / fertilization / acrosome reaction / human oocyte / human spermatozoa / 受精分子 / 先体反応 / ヒト卵 / ヒト精子 / genomic lmprinting / telomerase / mol gene / PXGR gene / CIS / テロメアーゼ活性 / モータリン蛋白 / クロナリティー / CIS病変 / 子宮頸部上皮内病変 / genomicimprinting現象 / genomic imprinting現象 / テロメラーゼ活性 / mol遺伝子 / PXGR遺伝子 / 異型上皮病変 / 子宮頚部癌 / regulatory element / N-glycosylation / oxytocin binding capacity / oxytocin unresponsiveness / ゲルシフトアッセイ / 発見調節領域 / 糖鎖 / 発現調節領域 / オキシトシン結合能 / 遺伝子多型 / オキシトシン不応症 / 遷延分娩 / RDS / Chorioamnionitis / Fetomaternal defense mechanism / Perinatal infection / Endocrine function / Trophoblast / placenta / Cytokine / タイロシン蛋白酵素 / 細胞内情報伝達経路 / ホルモン分泌調節 / 呼吸窮迫症候群 / 絨毛羊膜炎 / 母児生体防御能 / 周産期感染症 / ホルモン分泌調節機序 / 胎盤 / サイトカイン / 希少婦人科がん / がん組織バンク / テーラーメイドがん治療 / ヌードマウス同所移植 / 婦人科がん治療 / リンパ節転移遺伝子 / 癌の微小環境 / 蛍光細胞標識 / 細胞間相互作用 / 癌関連線維芽細胞 / 胎児脳循環 / 過換気 / 二酸化炭素分圧 / 胎児脳血流 / 二酸化炭素 / 胎児脳酸素化 / アンケート調査 / 選択的人工妊娠中絶 / 生命倫理学 / 市民意識 / 人工妊娠中絶 / 出生前診断 / 血流量 / ex vivo / マウスモデル / 生体内遺伝子導入 / リアルタイム計測 / 不妊症 / 体温 / 年齢 / ニューロゲネシス / アポトーシス / subgranular zone / subventricular zone / 未熟脳 / 放射線 / HVJリポオーム / NFkB Less

婦人科がん微小環境細胞の包括的解析－分子標的の発見から細胞療法を目指して－
- Principal Investigator
  
  村田卓也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kawasaki Medical School
The analysis focusing on ovarian granulosa cells from reproductive medicine to gynecological tumorsPrincipal Investigator
- Principal Investigator
  
  下屋浩一郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kawasaki Medical School
Subset cell analysis of gynecological cancer-associated fibroblast that induce lymph node metastasis.
- Principal Investigator
  
  村田卓也
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kawasaki Medical School
Elucidation of cervical cancer microenvirnment - aiming to supress cancer cell behavir affected by stromal cells
- Principal Investigator
  
  Takuya Murata
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kawasaki Medical School
An approach to pathological analysis of fetal and neonatal brain damage from the viewpoint of brain development (six layers of cerebrum)Principal Investigator
- Principal Investigator
  
  SHIMOYA KOICHIRO
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kawasaki Medical School
The management of labor and fetal cerebral oxygenation: the importance of carbon dioxide
- Principal Investigator
  
  Tomimatsu Takuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Reconstitution of gynecological cancer microenvirnment
- Principal Investigator
  
  Murata Takuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kawasaki Medical School
The regulation mechanism of uterine contraction: Association between Uterine myometrium and Immunological cells/oxidative stressPrincipal Investigator
- Principal Investigator
  
  SHIMOYA KOICHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kawasaki Medical School
Attitude of Japanese citizen for selective artifical abortion
- Principal Investigator
  
  YUICHIRO Nakai
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioethics
- Research Institution
  Kawasaki Medical School
The effects of endocrine and immunological factors in reproductive medicinePrincipal Investigator
- Principal Investigator
  
  SHIMOYA Koichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kawasaki Medical School
Development of a new method for evaluation of uterine receptivity
- Principal Investigator
  
  KIMURA Tadashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
ヒト神経幹細胞を用いた放射線脳障害メカニズムの解明とその臨床応用
- Principal Investigator
  
  FUKUDA Hirotsugu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Cardiovascular Center Research Institute
Development of molecular target therapy for human implantation failure focusing on nuclear transcription factor activity
- Principal Investigator
  
  KIMURA Tadashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Determination of physiology and pathology of oligohydramnios and intrauterine fetal death by using animal model and human analysisPrincipal Investigator
- Principal Investigator
  
  SHIMOYA Koichiro, 早田憲司
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Development of the treatment for neonatal for hypoxia-ischemia (HI) brain injury
- Principal Investigator
  
  MURATA Yuji
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Development of gene therapy model for implantation failure patients using transient gene transfer to uterine endometrium
- Principal Investigator
  
  KIMURA Tadashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Analysis of chemokine-chemokine receptor system in human female reproductive tissue and its functionPrincipal Investigator
- Principal Investigator
  
  SHIMOYA Koichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Abnormality of proliferation and differentiation of the trophoblasts in preeclampsia -Correlation between the cell cycle and oxidative stress-
- Principal Investigator
  
  KOYAMA Masayasu, 井阪茂之
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
着床期子宮内膜に対する遺伝子導入法の確立と着床不全モデルの確立
- Principal Investigator
  
  AZUMA Chihiro
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
The elucidation of the mechanism of abortion/ premature birth by the key enzymes (PLA2 and COX) in the arachidonic acid cascade
- Principal Investigator
  
  KOYAMA Masayasu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Analysis of function of protease inhibitor in the human reproduction area and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  SHIMOYA Koichiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
早産・絨毛羊膜炎の病態に関する分子生物学的解析および新たな評価診断法の開発Principal Investigator
- Principal Investigator
  
  下屋浩一郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
The effect of prostaglandin D synthetase (PGDS) on fertilization, ovum transport and implantation.
- Principal Investigator
  
  TOKUGAWA Yosihiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Comparison of pathogenesis between human uterine cervical dysplasia and carcinoma in situ
- Principal Investigator
  
  AZUMA Chihiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Analysis of molecules for fertilization on human spermatozoa and oocytes
- Principal Investigator
  
  OHASHI Kazutomo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
The analysis of genomic imprinting in ovarian teratomas and choriocarcinomaPrincipal Investigator
- Principal Investigator
  
  SIMOYA Kouichirou
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Analysis of the oxytocin unresponsiveness due to the mutant oxytocin receptor.
- Principal Investigator
  
  TOKUGAWA Yoshihiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University
Analysis of placental endocrine and immunological function regulated by placenta-derived cytokines
- Principal Investigator
  
  MITSUDA Nobuaki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Osaka University

[Book] 標準産科婦人科学第4版2011
- Author(s)
  下屋浩一郎
- Total Pages
  626
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21592118
[Book] 性感染症と生殖器感染(女性)2011
- Author(s)
  下屋浩一郎
- Total Pages
  317
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-21592118
[Book] 産婦人科レビュー生殖医療内科疾患と生殖2011
- Author(s)
  下屋浩一郎
- Publisher
  鍬谷書店
- Data Source
  KAKENHI-PROJECT-21592118
[Journal Article] Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normalization from aberrant epigenetic states on granulosa cell tumor cell lines.2022
- Author(s)
  Hazama Y, Tsujioka T, Kitanaka A, Tohyama K, Shimoya K.
- Journal Title
  
  PLoS One.
  
  Volume: 17(7) Issue: 7 Pages: 0271245-0271245
- DOI
  10.1371/journal.pone.0271245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09505, KAKENHI-PROJECT-22K07488, KAKENHI-PROJECT-20H03582
[Journal Article] Comprehensive analysis of cytokines in the follicular fluid and serum during in vitro fertilization and embryo transfer2021
- Author(s)
  Keiko MATSUMOTO, Takehiko MATSUYAMA, Shin OHIRA, Rumi NAKAZAWA, Yukiko HAZAMA, Takuya MORIYA, Ryo MATSUMOTO, Takafumi NAKAMURA, Koichiro SHIMOYA
- Journal Title
  
  Kawasaki Medical Journal
  
  Volume: 47 Pages: 167-178
- DOI
  10.11482/KMJ-E202147167
- ISSN
  0385-0234, 2434-3404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09505
[Journal Article] Unresponsiveness to oxytocin due to an extremely thin uterine wall in a pregnant woman with systemic lupus erythematosus and Sjögren's syndrome.2018
- Author(s)
  Tomimatsu T, Hazama Y, Takeuchi M, Kimura T, Shimoya K.
- Journal Title
  
  Unresponsiveness to oxytocin due to an extremely thin uterine wall in a pregnant woman with systemic lupus erythematosus and Sjögren's syndrome.
  
  Volume: Feb;38(2) Pages: 276-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10695
[Journal Article] The Analysis of Cell Cycle-related Proteins in Ovarian Clear Cell Carcinoma Versus High-grade Serous Carcinoma.2017
- Author(s)
  Hazama Y, Moriya T, Sugihara M, Sano R, Shiota M, Nakamura T, Shimoya K.
- Journal Title
  
  Int J Gynecol Pathol.
  
  Volume: Oct 10 Issue: 6 Pages: 516-524
- DOI
  10.1097/pgp.0000000000000461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10695
[Journal Article] Vasohibin-1 Is a Poor Prognostic Factor of Ovarian Carcinoma2017
- Author(s)
  Sano R, Kanomata N, Suzuki S, Shimoya K, Sato Y, Moriya T, Shiota M.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 243 Issue: 2 Pages: 107-114
- DOI
  10.1620/tjem.243.107
- NAID
  130006178275
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10695
[Journal Article] Maternal Depression and Mother-to-Infant Bonding: The Association of Delivery Mode, General Health and Stress Markers2017
- Author(s)
  Mihyon Song, Hiroshi Ishii, Masahiro Toda, Takuji Tomimatsu, Hironobu Katsuyama, Yuichiro Nakai, Koichiro Shimoya
- Journal Title
  
  Open Journal of Obstetrics and Gynecology
  
  Volume: 7 Issue: 02 Pages: 155-166
- DOI
  10.4236/ojog.2017.72017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10695
[Journal Article] Guillain-Barré syndrome after trivalent influenza vaccination during pregnancy.2016
- Author(s)
  Tomimatsu T, Sugihara M, Nagai T, Sunada Y, Kimura T, Shimoya K.
- Journal Title
  
  Eur J Obstet Gynecol Reprod Biol.
  
  Volume: 201 Pages: 225-226
- DOI
  10.1016/j.ejogrb.2016.03.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462506, KAKENHI-PROJECT-15K10695
[Journal Article] Massive cystic degeneration of a uterine leiomyoma in a patient with autosomal dominant polycystic kidney disease.2015
- Author(s)
  Tomimatsu T, Sugihara M, Nakamura T, Kashihara N, Shimoya K.
- Journal Title
  
  Gynecologic and Obstetric Investigation
  
  Volume: 79 Issue: 3 Pages: 168-171
- DOI
  10.1159/000369996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462506, KAKENHI-PROJECT-26462488
[Journal Article] Abnormal pressure-wave reflection in pregnant women with chronic hypertension: association with maternal and fetal outcomes2014
- Author(s)
  Tomimatsu, T. Fujime, M. Kanayama, T. Mimura, K. Koyama, S. Kanagawa, T. Endo, M. Shimoya, K. Kimura, T.
- Journal Title
  
  Hypertens Res
  
  Volume: 37 Issue: 11 Pages: 989-992
- DOI
  10.1038/hr.2014.109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249080, KAKENHI-PROJECT-24592493, KAKENHI-PROJECT-26462506
[Journal Article] Timing of cisplatin administration for chemoradiotherapy in transgenic mice bearing lens tumors.2014
- Author(s)
  Kaku S, Ushioda N, Ishii H, Murakami T, Takahashi K, Nakai Y, Shimoya K, Nakamura T
- Journal Title
  
  Oncology Report
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592493
[Journal Article] Association between sexual health and delivery mode2014
- Author(s)
  Song, M. Ishii, H. Toda, M. Tomimatsu, T. Katsuyama, H. Nakamura, T. Nakai, Y. Shimoya, K.
- Journal Title
  
  Sex Med
  
  Volume: 2 Issue: 4 Pages: 153-158
- DOI
  10.1002/sm2.46
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249080, KAKENHI-PROJECT-24592493, KAKENHI-PROJECT-26462506
[Journal Article] 妊産婦におけるアロマ吸引によるストレス軽減効果の検討2014
- Author(s)
  宋美玄, 石井浩志, 比名朋子, 石田剛, 中井祐一郎, 戸田雅裕, 下屋浩一郎
- Journal Title
  
  アロマテラピー学雑誌
  
  Volume: 14 Pages: 52-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592493
[Journal Article] 【血栓・止血の異常と妊娠】坑リン脂質抗体症候群と妊娠2013
- Author(s)
  下屋浩一郎
- Journal Title
  
  産科と婦人科
  
  Volume: 80 Pages: 61-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592493
[Journal Article] 分娩誘発の頸管熟化処置におけるフォーリーカテーテルの有用性と安全性についての検討2013
- Author(s)
  郭翔志, 石田剛, 佐野力哉, 張良実, 前田岳史, 冨松拓治, 中井祐一郎, 高橋健太郎, 村上節, 下屋浩一郎
- Journal Title
  
  日本周産期・新生児医学会雑誌
  
  Volume: 49 Pages: 238-243
- NAID
  10031176899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592493
[Journal Article] 当科における妊娠糖尿病新基準による管理2013
- Author(s)
  杉原弥香, 羽間夕紀子, 佐野力哉, 石田剛, 宋美玄, 村田卓也, 福家信二, 冨松拓治, 中井祐一郎, 中村隆文, 下屋浩一郎
- Journal Title
  
  現代産婦人科
  
  Volume: 62 Pages: 59-63
- NAID
  10031203929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592493
[Journal Article] 当院におけるHPVワクチンの接種完遂率の検討2013
- Author(s)
  羽間夕紀子, 杉原弥香, 佐野力哉, 石田剛, 宋美玄, 村田卓也, 福家信二, 冨松拓治, 中井祐一郎, 中村隆文, 下屋浩一郎
- Journal Title
  
  現代産婦人科
  
  Volume: 62 Pages: 65-67
- NAID
  10031203930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592493
[Journal Article] 【知っておきたい重症産褥合併症】産褥管理の総論2012
- Author(s)
  下屋浩一郎
- Journal Title
  
  産科と婦人科
  
  Volume: 79 Pages: 1087-1092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592493
[Journal Article] 出生前診断に関わる問題に対する産ふじか以外の医師の意識に関する検討2011
- Author(s)
  張良実、中井祐一郎、佐野力哉、石田剛、下屋浩一郎ほか
- Journal Title
  
  現代産婦人科
  
  Volume: 60 Pages: 139-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23613010
[Journal Article] Change of the salivary stress marker concentrations during pregnancy2011
- Author(s)
  H Tsubouchi, Shimoya K, et al.
- Journal Title
  
  Maternal depressive status suppress the changes of those levels
  
  Volume: 37(8) Pages: 1004-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592118
[Journal Article] クリニカルカンファランス周産期科学的な視点から分娩の生理と病理を探る子宮収縮の生理と病理2011
- Author(s)
  下屋浩一郎
- Journal Title
  
  日本産科婦人科学会雑誌
  
  Volume: 63巻 Pages: 244-250
- Data Source
  KAKENHI-PROJECT-21592118
[Journal Article] Effects of 4-Hydroxy-2-Nonenal, a Major Lipid Peroxidation-Derived Aldehyde, and N-Acetylcysteine on the Cyclooxygenase-2 Expression in Human Uterine Myometrium2011
- Author(s)
  K Temma-Asano, Shimoya K, et al.
- Journal Title
  
  Gynecol Obstet Invest
  
  Volume: 72(1) Pages: 37-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592118
[Journal Article] Maternal blood serum and plasma human tumor-associated antigen RCAS1 during the course of uncomplicated pregnancies : a prospective study2010
- Author(s)
  Tskitishvili E, Shimoya K, et al.
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 64(3) Pages: 218-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592118
[Journal Article] Human C-reactive protein enhances vulnerability of immature rats to hypoxic-ischemic brain damage : a preliminary study2010
- Author(s)
  Kinugasa-Taniguchi Y, Shimoya K, et al.
- Journal Title
  
  Reprod Sci
  
  Volume: 17(5) Pages: 419-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592118
[Journal Article] The effect of tumor-associated protein RCAS1 gene silencing on bloodpressure and urinary protein excretion in pregnant mouse : a pilot study2010
- Author(s)
  Tskitishvili E, Shimoya K, et al.
- Journal Title
  
  Am J Obstet Gynecol
  
  Volume: 203(4) Pages: 6-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592118
[Journal Article] Maternal urinoma during pregnancy2008
- Author(s)
  Ushioda N, Matsuo K, Nagamatsu M, Kimura T, Shimoya K.
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research 34
  
  Pages: 88-91
- NAID
  10021250356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390429
[Journal Article] Maternal positioning and fetal positioning in utero2007
- Author(s)
  Koji Matsuo, Koichiro Shimoya, Norichika Ushioda, Tadashi Kimura
- Journal Title
  
  The Journal of Obstetrics and Gynaecology Re search 33
  
  Pages: 279-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390429
[Journal Article] Relationship between human tumor-associated antigen RCAS1 and gestational diabetes mellitus2007
- Author(s)
  Tskitishvili, E., Komoto, Y., Kinugasa, Y., Kanagawa, T., Song, M., Mimura, K., Tomimatsu, T., Kimura, T., Shimoya, K.
- Journal Title
  
  American Journal of Reproductive Immunology 58
  
  Pages: 440-446
- Data Source
  KAKENHI-PROJECT-19390429
[Journal Article] Rapid detection of trisomy 21 by gene dosage analysis using quantitative real-time PCR2006
- Author(s)
  Tsujie T, Kimura T, Shimoya K, Tsutsui T, et al.
- Journal Title
  
  J Obstet Gynaecol Res 32
  
  Pages: 368-372
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591734
[Journal Article] 既往歴・合併症と妊娠のリスク評価2006
- Author(s)
  下屋浩一郎他
- Journal Title
  
  臨床産婦人科 60
  
  Pages: 960-963
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Murata Y The expression of fractalkine in the endometrium during the menstrual cycle2006
- Author(s)
  Watanabe M, Shimoya K, Temma-Asano K, Kimura T
- Journal Title
  
  Int J Gynecol Obstet 92
  
  Pages: 242-247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] 妊娠高血圧症候群と栄養-塩分・体重増加について2006
- Author(s)
  下屋浩一郎他
- Journal Title
  
  平成17年度病栄協ガイドブック周産期の栄養
  
  Pages: 23-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Murata Y The effects of repeated corticosteroid administration on the neurogenesis in the neonatal rat2006
- Author(s)
  Kanagawa T, Tomimatsu T, Hayashi S, Shioji M, Fukuda H, Shimoya K
- Journal Title
  
  Am J Obstet Gynecol 194
  
  Pages: 231-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Rapid detection of trisomy 21 by gene dosage analysis using quantitative real-time PCR2006
- Author(s)
  Tsujie T, Takemura M, Kimura T, Shimoya K, Tsutsui T. et al.
- Journal Title
  
  Journal of Obetetrics and Gynaecology Research 32
  
  Pages: 368-372
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591734
[Journal Article] Murata Y Long-term neuroprotective effects of carbon dioxide on neonatal rat hypoxic-ischemic brain injury : an experimental study of skilled motor tasks2006
- Author(s)
  Kohzuki M, Tomimatsu T, Fukuda H, Kanagawa T, Kanzaki T, Shimoya K
- Journal Title
  
  Am J Obstet Gynecol 195
  
  Pages: 240-245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Murata Y Reduction of aquaporin-8 on fetal membranes under oligohydramnios in mice lacking prostaglandin F2 alpha receptor2006
- Author(s)
  Shioji M, Fukuda H, Kanzaki T, Wasada K, Kanagawa T, Shimoya K, Mu J, Sugimoto Y
- Journal Title
  
  J Obstet Gynecol Res 32
  
  Pages: 373-378
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] 微弱陣痛と難産2006
- Author(s)
  下屋浩一郎他
- Journal Title
  
  ペリネイタルケア 25
  
  Pages: 985-989
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Murata Y S100B protein expression in the amnion and amniotic fluid in pregnancies complicated by pre-eclampsia2006
- Author(s)
  Tskitishivili E, Komoto Y, Temma-Asano K, Hayashi S, Kinugasa Y, Tsubouchi H, Song M, Kanagawa T, Shimoya K
- Journal Title
  
  Mol Human Reprod 12
  
  Pages: 755-761
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] The expression of fractalkine in the endometrium during menstrual cycle2006
- Author(s)
  Watanabe, M., Shimoya, K., Zhang, Q., Temma-Asano, K., Kimura, T., Murata, Y.
- Journal Title
  
  Int J Gynecol Obstet (in press)
- Data Source
  KAKENHI-PROJECT-17591734
[Journal Article] Murata Y Prospective study of non-closure or closure of the peritoneum at cesarean delivery in 124 women : Impact of prior peritoneal closure at primary cesarean on the interval time between first cesarean section and the next pregnancy and significant adhesion at second cesarean2006
- Author(s)
  Komoto Y, Shimoya K, Shimizu T, Kimura T, Hayashi S, Temma-Asano K, Kanagawa T, Fukuda H
- Journal Title
  
  J Obstet Gynecol Res 32
  
  Pages: 396-402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Murata Y Effect of coffee intake on blood flow and maternal stressduringthe third trimester of pregnancy2006
- Author(s)
  Tsubouchi H, Shimoya K, Hayashi S, Toda M, Fukuda H
- Journal Title
  
  Int J Gynecol Obstet 92
  
  Pages: 19-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Koyama M, Murata Y Secretory leukocyte protease inhibitor levels in cervicovaginal secretion of elderly women2006
- Author(s)
  Shimoya K, Zhang Q, Temma K, Kimura T, Tsujie T, Tsuitsui T, Wasada K, kanzaki T
- Journal Title
  
  Maturitas 54
  
  Pages: 141-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Murata Y Cesarean delivery after successful external cephalic version of breech presentation at term2006
- Author(s)
  Matsuzaki S, Shimoya K
- Journal Title
  
  Int J Gynecol Obstet 93
  
  Pages: 248-249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Secretory leukocyte protease inhibitor levels in cervicovaginal secretion of elderly women2006
- Author(s)
  Shimoya K, et al.
- Journal Title
  
  Maturitas 54
  
  Pages: 141-148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Secretory leukocyte protease inhibitor levels in cervicovaginal secretion of elderly women2005
- Author(s)
  Shimoya K. et al.
- Journal Title
  
  Maturitus (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591746
[Journal Article] Fractalkine in the peritoneal fluid of women with endometriosis2005
- Author(s)
  Shimoya K, et al.
- Journal Title
  
  Int J gynecol Obstet 91
  
  Pages: 36-41
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Murata Y Helicobacter pylori infection and platelet counts during pregnancy2005
- Author(s)
  Fukui O, Shimoya K, Shimizu T, Fukuda H, Wasada K
- Journal Title
  
  Int J Gynecol Obstet 89
  
  Pages: 26-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Fractalkine in the peritoneal fluid of women with endometriosis2005
- Author(s)
  Shimoya, K
- Journal Title
  
  Int J Gynaecol Obstet 91
  
  Pages: 36-41
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Murata Y Fractalkine in the peritoneal fluid of women with endometriosis2005
- Author(s)
  Shimoya K, Zhang Q, Temma-Asano K, Hayashi S, Kimura T
- Journal Title
  
  Int J Gynecol Obstet 91
  
  Pages: 36-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] 胎児評価法について2005
- Author(s)
  下屋浩一郎他
- Journal Title
  
  妊娠中毒症から妊娠高血圧症候群へ
  
  Pages: 286-287
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] 妊娠前からのカウンセリングの意義こついて2005
- Author(s)
  下屋浩一郎他
- Journal Title
  
  Pharma Medica 23
  
  Pages: 49-52
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Fractalkine in the peritoneal fluid of women with endometriosis2005
- Author(s)
  Shimoya K, et al.
- Journal Title
  
  Int J Gynecol Obstet 91
  
  Pages: 36-41
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209054
[Journal Article] Secretory leukocyte protease inhibitor levels in cervicovaginal secretion of elderly women2004
- Author(s)
  Shimoya K.et al.
- Journal Title
  
  Maturitus (In press)
- Data Source
  KAKENHI-PROJECT-15591746
[Journal Article] Murata Y Effects of 4-hydroxy-2-nonenal, a marker of oxidative stress, on the cyclooxygenase-2 of human placenta in chorioamnionitis2004
- Author(s)
  Temma K, Shimoya K, Zhang Q, Kimura T, Wasada K, Kanzaki T, Azuma C, Koyama M
- Journal Title
  
  Mol human Reprod 10
  
  Pages: 167-171
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] 妊娠とその異常2004
- Author(s)
  下屋浩一郎他
- Journal Title
  
  別冊医学のあゆみサイトカイン-State of arts
  
  Pages: 321-324
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390476
[Journal Article] Secretory leukocyte protease inhibitor levels in cervicovaginal secretion of elderly women2004
- Author(s)
  Shimoya K. et al.
- Journal Title
  
  Maturitus (印刷中)
- Data Source
  KAKENHI-PROJECT-15209054
[Journal Article] Secretory leukocyte protease inhibitor levels in cervicovaginal secretion of elderly women
- Author(s)
  Shimoya, K
- Journal Title
  
  Maturitas (in press)
- Data Source
  KAKENHI-PROJECT-16390476
[Patent] ピロールイミダゾールポリアミド化合物を有効成分とするがん転移阻害剤2022
- Inventor(s)
  村田卓也, 下屋浩一郎, 杉山弘, 池田修司
- Industrial Property Rights Holder
  村田卓也, 下屋浩一郎, 杉山弘, 池田修司
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-21K09554
[Patent] ピロールイミダゾールポリアミド化合物を有効成分とするがん転移阻害剤2021
- Inventor(s)
  村田卓也, 下屋浩一郎, 杉山弘, 池田修司
- Industrial Property Rights Holder
  村田卓也, 下屋浩一郎, 杉山弘, 池田修司
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-066356
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K09554
[Presentation] 体外受精における卵胞液中のサイトカインの網羅的解析2021
- Author(s)
  松本桂子, 松山毅彦, 中澤留美, 羽間夕紀子, 松本良, 下屋浩一郎
- Organizer
  日本生殖医学会
- Data Source
  KAKENHI-PROJECT-21K09505
[Presentation] 周産期医療と女性医学2015
- Author(s)
  下屋浩一郎
- Organizer
  第20回日本女性医学学会ワークショップ
- Place of Presentation
  東武ホテルグランデ宇都宮（栃木県）
- Year and Date
  2015-02-28
- Invited
- Data Source
  KAKENHI-PROJECT-24592493
[Presentation] 分娩時の諸要素が産後うつ・産褥の母子愛着・女性性機能に与える影響2014
- Author(s)
  宋美玄, 羽間夕紀子, 佐野力哉, 杉原弥香, 梅本雅彦, 村田卓也, 福家信二, 冨松拓治, 中井祐一郎, 中村隆文, 塩田充, 下屋浩一郎
- Organizer
  第66回日本産科婦人科学会
- Place of Presentation
  東京国際フォーラム（東京都）
- Year and Date
  2014-04-18
- Data Source
  KAKENHI-PROJECT-24592493
[Presentation] 細胞周期制御因子のグリア細胞分化に及ぼす影響の解析-新生児脳障害の病態改善に向けて-2014
- Author(s)
  石田剛, 冨松拓治, 羽間夕紀子, 杉原弥香, 佐野力哉, 宋美玄, 中井祐一郎, 塩田充, 下屋浩一郎
- Organizer
  第50回日本周産期・新生児医学会
- Place of Presentation
  シェラトン・グランデ・トーキョーベイ・ホテル（千葉県）
- Year and Date
  2014-07-15
- Data Source
  KAKENHI-PROJECT-24592493
[Presentation] 脳形成時に神経前駆細胞が神経系細胞へ分化するメカニズムの解析―新生児脳障害の治療に向けて―2014
- Author(s)
  石田剛, 冨松拓治, 中井祐一郎, 中村隆文, 小曽戸陽一, 樋田一徳, 下屋浩一郎
- Organizer
  第66回日本産科婦人科学会
- Place of Presentation
  東京国際フォーラム（東京都）
- Year and Date
  2014-04-18
- Data Source
  KAKENHI-PROJECT-24592493
[Presentation] 妊娠と免疫グロブリン-血小板減少などの合併症を中心に-2011
- Author(s)
  下屋浩一郎
- Organizer
  第1回周産期血液・免疫研究会
- Place of Presentation
  神戸
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-21592118
[Presentation] 科学的な視点から分娩の生理と病理を探る子宮収縮の生理と病理2011
- Author(s)
  下屋浩一郎
- Organizer
  第63回日本産科婦人科学会学術講演会
- Place of Presentation
  大阪
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-21592118
[Presentation] 合併症を有する女性の不妊治療・周産期医療2011
- Author(s)
  下屋浩一郎
- Organizer
  第91回北海道医学大会産婦人科分科会
- Place of Presentation
  旭川
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21592118
[Presentation] 周産期脳障害と感染の関連機序および予防の可能性についての検討　－新生仔ラットモデルを用いて－
- Author(s)
  冨松拓冶，味村和哉，谷口友其子，中井祐一郎，下屋浩一郎，木村正
- Organizer
  第49回日本周産期・新生児医学会
- Place of Presentation
  横浜（パシフィコ横浜・会議センター）
- Data Source
  KAKENHI-PROJECT-24592493
[Presentation] 脳形成時に神経前駆細胞が神経系細胞へ分化するメカニズムの解析―新生児脳障害の治療に向けて―
- Author(s)
  石田剛, 冨松拓治, 中井祐一郎, 中村隆文, 小曽戸陽一, 樋田一徳, 下屋浩一郎
- Organizer
  第66回日本産科婦人科学会
- Place of Presentation
  東京(東京国際フォーラム)
- Data Source
  KAKENHI-PROJECT-24592493
[Presentation] ヒト生殖・周産期領域における6Ckineを中心としたリンパ球・NK細胞・樹状細胞制御機構の解明
- Author(s)
  下屋浩一郎
- Organizer
  第3回川崎医科大学学術集会
- Place of Presentation
  川崎医科大学（倉敷市）
- Data Source
  KAKENHI-PROJECT-24592493

1. MURATA Takuya (20714207)

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2. AZUMA Chihiro (20151061)

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38. WATANABE Masanobu (00418774)

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50. 福井温

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51. MIMURA Kazuya

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52. 中村仁美

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Shimoya Kouichirou 下屋 浩一郎

SHIMOYA Kouichiro 下屋 浩一郎

SIMOYA Kouichirou 下屋 浩一郎

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The analysis focusing on ovarian granulosa cells from reproductive medicine to gynecological tumorsPrincipal Investigator

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An approach to pathological analysis of fetal and neonatal brain damage from the viewpoint of brain development (six layers of cerebrum)Principal Investigator

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The regulation mechanism of uterine contraction: Association between Uterine myometrium and Immunological cells/oxidative stressPrincipal Investigator

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The effects of endocrine and immunological factors in reproductive medicinePrincipal Investigator

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Determination of physiology and pathology of oligohydramnios and intrauterine fetal death by using animal model and human analysisPrincipal Investigator

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Shimoya Kouichirou 下屋浩一郎

SHIMOYA Kouichiro 下屋浩一郎

SIMOYA Kouichirou 下屋浩一郎