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Tsuge Hideaki  津下 英明

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… Alternative Names

TSUGE Hideaki  津下 英明

津下 秀明  ツゲ ヒデアキ

津下 英明  ツゲ ヒデアキ

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Researcher Number 40299342
Other IDs
External Links
Affiliation (Current) 2025: 京都産業大学, 生命科学部, 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 京都産業大学, 生命科学部, 教授
2019: 京都産業大学, 生命科学部, 教授
2011 – 2018: 京都産業大学, 総合生命科学部, 教授
2012: 京都産業大学, 公私立大学の部局等, 教授
2010 – 2011: 京都産業大学, 総合生命学部, 教授 … More
2003 – 2009: 徳島文理大学, 健康科学研究所, 教授
2000: 徳島文理大学, 家政学部兼健康科学研究所, 助教授
1998 – 1999: 徳島文理大学, 家政学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Basic Section 43040:Biophysics-related / General medical chemistry / Biological Sciences / Structural biochemistry / Medium-sized Section 38:Agricultural chemistry and related fields
Except Principal Investigator
Basic Section 38030:Applied biochemistry-related / Applied biochemistry / Biophysics / Bacteriology (including Mycology) / Applied microbiology … More / Drug development chemistry / Applied materials science/Crystal engineering / Functional biochemistry / Biological Sciences Less
Keywords
Principal Investigator
ADPリボシル化 / クライオ電子顕微鏡 / アクチン / RhoA / C3 / タンパク質膜透過 / 二成分毒素 / X線結晶構造解析 / モノADPリボシル化 / Ia … More / 結晶構造解析 / 膜孔形成毒素 / ディフィシル菌 / 複合体 / 膜結合 / フォールディング / 複合体構造解析 / ホスト認識 / 細菌毒素 / ADPリボシルトランスフェラーゼ / 複合体結晶構造解析 / 特異性 / スフィンゴミエリナーゼ / 1分子測定 / トキシン膜透過システム / RNA N-glycosidase / リボソーム / リボソーム不活性化タンパク / トキシン透過システム / 動的構造解析 / クライオ 電子顕微鏡 / アンフォールディング / 電気生理 / タンパク質膜透過機構 / トランスロコン / 膜孔 / アンフォールド / イオタ毒素 / 超分子複合体 / 単粒子解析 / ウェルシュ菌 / 構造酵素学 / Rac1 / CPILE-a / 基質タンパク質認識 / 修飾アミノ酸認識機構 / 基質タンパク質認識機構 / タンパク質複合体 / Cdc42 / 基質特異性 / metal-binding / apotosis / ceramide / sphingomyelinase / 阻害剤 / 酵素 / 脂質ラフト / アポトーシス / 金属結合 / セラミド / スフィンゴミエリン / リン脂質 / SpvB / 翻訳後修飾 / Rho GTPase / 外部シャペロン / サブチリシン様セリンプロテアーゼ / 反応機構 / 複合体構造 / 毒素 / 細菌 / C3毒素 / 複合体解析 / 局在化 / 結晶化 / 巻き戻し / スフィンゴシン1リン酸 / スフィンゴミエリン代謝系酵素 / スフィンゴシンキナーゼ / スフィンゴミエリン代謝酵素 / 構造生物学 … More
Except Principal Investigator
DyP / タンパク質工学 / 分子進化 / DyP型ペルオキシダーゼ / X線結晶構造解析 / カテプシン阻害 / Komagataeibacter xylinus / セルロース生産菌 / エンカプスリン / タンパク質機能 / 立体構造のトポロジー / 収束進化 / DyP型ペルオキシダーゼ / X線小角散乱 / 胃がん / ピロリ菌 / phospholipid / divalent metal cation / hemolysis / crystal analysis / sphinogmyelinase / Bacillus cereus / alpha-toxin / Clostridium perfrngens / スフィンゴシン1-リン酸 / スフィンゴミエリン / リン脂質 / 二価金属イオン / 溶血 / 結晶解析 / スフィンゴミエリナーゼ / セレウス菌 / α毒素 / ウエルシュ菌 / Crystal structure analysis / DNA-binding protein / Alteration of substrate specificity / Protein engineering / Restriction endonuclease / 構造生物学 / DNA認識機構 / 転写制御因子 / 界面活性剤 / 金属イオン / 部位特異的変異 / 結晶化 / エンドヌクレアーゼ / 制限修飾系 / 結晶構造解析 / DNA結合タンパク質 / 特異性改変 / 制限酵素 / cytolysin / infection / 細胞溶解毒素 / 感染症 / 液液相分離 / 脱塩 / タンパク質 / コロイド結晶 / 遠心濃縮 / タンパク質結晶 / コロイド結晶化 / EfeB / クロロジスムターゼ / DyP-typeペルオキシダーゼ / スイングメカニズム / ペルオキシダーゼ / 加水分解 / アントラキノン / 基質結合部位 / スイングモデル / 反応メカニズム / DyP / 触媒メカニズム / リソゾーム / リソアポプターゼ / カスパーゼ / 癌細胞 / アポプトーシス / 阻害剤開発 / カテプシン / 蛋白立体構造 / IgE産生 / 免疫抑制 / 骨吸収 / ビタミンB_6 / ピリドキサール燐酸 Less
  • Research Projects

    (21 results)
  • Research Products

    (175 results)
  • Co-Researchers

    (21 People)
  •  Toxin membrane translocation system approached by liposome single particle analysisPrincipal Investigator

    • Principal Investigator
      津下 英明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Kyoto Sangyo University
  •  Role of encapsulin and DyP from cellulose high-producing bacateria

    • Principal Investigator
      菅野 靖史
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38030:Applied biochemistry-related
    • Research Institution
      Japan Women's University
  •  Cryo-EM structure analysis of the complex of ribosome inactivating protein and ribosomePrincipal Investigator

    • Principal Investigator
      津下 英明
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 38:Agricultural chemistry and related fields
    • Research Institution
      Kyoto Sangyo University
  •  Dynamic Structural Analysis of Protein Translocation Across Membrane by Cryo-EMPrincipal Investigator

    • Principal Investigator
      津下 英明
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Kyoto Sangyo University
  •  Structural and Functional Study of Binary Toxin Translocon by Cryo-EM and X-ray CrystallographyPrincipal Investigator

    • Principal Investigator
      TSUGE Hideaki
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Kyoto Sangyo University
  •  Rho GTPase Recognition Mechanism of ADP-ribosylating C3 exoenzymePrincipal Investigator

    • Principal Investigator
      TSUGE Hideaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto Sangyo University
  •  Structure-activity relationship of carcinogenic factor, Tip-alpha, from Helicobacter pylori

    • Principal Investigator
      TSURUMURA Toshiharu
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      Kyoto Sangyo University
  •  Rational design of DyP type peroxidase based on the topology

    • Principal Investigator
      SUGANO Yasushi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied biochemistry
    • Research Institution
      Japan Women's University
  •  複合体構造解析による細菌毒素の標的結合タンパク質認識機構の解明Principal Investigator

    • Principal Investigator
      津下 英明
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto Sangyo University
  •  Colloidal crystallization of protein molecules

    • Principal Investigator
      SUZUKI Yoshihisa
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied materials science/Crystal engineering
    • Research Institution
      The University of Tokushima
  •  複合体構造解析によるADPリボシル化毒素の標的タンパク質認識機構の解明Principal Investigator

    • Principal Investigator
      津下 英明
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto Sangyo University
  •  Characterization of the catalytic mechanism of DyP which is a representative novel peroxidase family.

    • Principal Investigator
      SUGANO Yasushi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Japan Women's University
      Tokyo Institute of Technology
  •  Structural and functional basis of the complex of mono-ADP-ribosylating toxin and substrate proteinPrincipal Investigator

    • Principal Investigator
      TSUGE Hideaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyoto Sangyo University
      Tokushima Bunri University
  •  Structural and cell biological study of sphingolipid metabolic enzymePrincipal Investigator

    • Principal Investigator
      TSUGE Hideaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Tokushima Bunri University
  •  Structural basis of the neutral sphingomyelinase to understand the lipid raftPrincipal Investigator

    • Principal Investigator
      TSUGE Hideaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokushima Bunri University
  •  Structural analysis of endonuclease-DNA interaction and alteration of substrate specificity

    • Principal Investigator
      KITA Keiko
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied microbiology
    • Research Institution
      Kyoto University
  •  Molecular biological and structural analysis of toxic and enzymatic activities in Clostridium perfringens alpha-toxin

    • Principal Investigator
      SAKURAI J.
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Tokushima Bunri University
  •  Dynamic structure of intermedilysin : Analysis of membrane binding region

    • Principal Investigator
      OHKURA Kazuto
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Nagoya University
  •  リソゾーム由来の新カスパーゼ3活性化酵素と肝癌におけるこの欠如

    • Principal Investigator
      勝沼 信彦
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokushima Bunri University
  •  蛋白立体構造に基づく6種カテプシン分別阻害剤開発とそれによる新生理機能の解明

    • Principal Investigator
      勝沼 信彦
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tokushima Bunri University
  •  ビタミンB_6による抗原プロセッシンダ酵素カテプシンBの阻害と免疫応答抑制

    • Principal Investigator
      KATUNUMA Nobuhiko
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tokushima Bunri University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] 構造生物学-ポストゲノム時代のタンパク質研究-(倉光成紀, 杉山政則 編)2007

    • Author(s)
      津下英明 等
    • Total Pages
      261
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors2024

    • Author(s)
      Falke S, Lieske J, Herrmann A, Loboda J, Karnicar K, Guther S, Reinke PYA, Ewert W, Usenik A, Lindic, Sekirnik A, Dretnik K, Tsuge H, Turk V, Chapman HN, Hinrichs W, Ebert G, Turk D, Meents A.
    • Journal Title

      J Med Chem

      Volume: 67,9 Issue: 9 Pages: 7048-7067

    • DOI

      10.1021/acs.jmedchem.3c02351

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Journal Article] Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile2022

    • Author(s)
      Kawamoto Akihiro、Yamada Tomohito、Yoshida Toru、Sato Yusui、Kato Takayuki、Tsuge Hideaki
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 6119-6119

    • DOI

      10.1038/s41467-022-33888-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21J13410, KAKENHI-PROJECT-20K15763, KAKENHI-PROJECT-21H02452
  • [Journal Article] Preparation of Clostridium perfringens binary iota-toxin pore complex for structural analysis using cryo-EM2021

    • Author(s)
      Yamada T, Tsuge H.
    • Journal Title

      Methods Enzymol.

      Volume: 649 Pages: 125-148

    • DOI

      10.1016/bs.mie.2021.01.032

    • ISBN
      9780128238585
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Journal Article] Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex2020

    • Author(s)
      Yamada Tomohito、Yoshida Toru、Kawamoto Akihiro、Mitsuoka Kaoru、Iwasaki Kenji、Tsuge Hideaki
    • Journal Title

      Nature Structural & Molecular Biology

      Volume: 27 Issue: 3 Pages: 288-296

    • DOI

      10.1038/s41594-020-0388-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06170, KAKENHI-PROJECT-18K14639
  • [Journal Article] Substrate N2 atom recognition mechanism in pierisin family DNA-targeting, guanine-specific ADP-ribosyltransferase ScARP2018

    • Author(s)
      Yoshida Toru、Tsuge Hideaki
    • Journal Title

      Journal of Biological Chemistry

      Volume: 293 Issue: 36 Pages: 13768-13774

    • DOI

      10.1074/jbc.ac118.004412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15095, KAKENHI-PROJECT-18K06170
  • [Journal Article] Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin.2017

    • Author(s)
      Toniti, W., Yoshida, T., Tsurumura, T., Irikura, D., Monma, C., Kamata, Y., and Tsuge, H.
    • Journal Title

      PLoS ONE

      Volume: 12 Issue: 2 Pages: e0171278-e0171278

    • DOI

      10.1371/journal.pone.0171278

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16J09051, KAKENHI-PROJECT-15K08289
  • [Journal Article] Comparative Studies of Actin- and Rho-Specific ADP-Ribosylating Toxins: Insight from Structural Biology2017

    • Author(s)
      Tsuge H, Tsurumura T, Toda A, Murata H, Toniti W, Yoshida T.
    • Journal Title

      Curr Top Microbiol Immunol.

      Volume: 399 Pages: 69-86

    • DOI

      10.1007/82_2016_23

    • ISBN
      9783319500461, 9783319500478
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Journal Article] Involvement of the Arg566 residue of Aeromonas sobria serine protease in substrate specificity.2017

    • Author(s)
      Kobayashi H, Otsubo T, Teraoka F, Ikeda K, Seike S, Takahashi E, Okamoto K, Yoshida T, Tsuge H, Yamanaka H
    • Journal Title

      PLoS One

      Volume: - Issue: 10 Pages: e0186392-e0186392

    • DOI

      10.1371/journal.pone.0186392

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08289, KAKENHI-PROJECT-16K18926
  • [Journal Article] Anabaena sp. DyP-type peroxidase is a tetramer consisting of two asymmetirc dimers2016

    • Author(s)
      T. Yoshida, H.J.O. Ogola, Y. Amano, T. Hisabori, H. Ashida, Y. Sawa, H. Tsuge, Y. Sugano
    • Journal Title

      Proteins

      Volume: 84 Issue: 1 Pages: 31-42

    • DOI

      10.1002/prot.24952

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26450132
  • [Journal Article] Reaction Mechanism of Mono-ADP-Ribosyltransferase Based on Structures of the Complex of Enzyme and Substrate Protein2015

    • Author(s)
      Tsuge H, Tsurumura T.
    • Journal Title

      Curr Top Microbiol Immunol

      Volume: 384 Pages: 69-87

    • DOI

      10.1007/82_2014_415

    • ISBN
      9783319107707, 9783319107714
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Journal Article] Structural Basis for Action of the External Chaperone for a Propeptide-deficient Serine Protease from Aeromonas sobria2015

    • Author(s)
      Kobayashi H, Yoshida T, Miyakawa T, Tashiro M, Okamoto K, Yamanaka H, Tanokura M, Tsuge H.
    • Journal Title

      J Biol Chem

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Journal Article] Conformational plasticity is crucial for C3-RhoA complex formation by ARTT-loop2015

    • Author(s)
      Tsuge H, Yoshida T, Tsurumura T
    • Journal Title

      Pathog Dis

      Volume: 73 Issue: 9 Pages: ftv094-ftv094

    • DOI

      10.1093/femspd/ftv094

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Journal Article] Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure2015

    • Author(s)
      Toda A, Tsurumura T, Yoshida T, Tsumori Y, Tsuge H.
    • Journal Title

      J Biol Chem

      Volume: 290 Issue: 32 Pages: 19423-32

    • DOI

      10.1074/jbc.m115.653220

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Journal Article] Crystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virus2014

    • Author(s)
      Tsurumura T, Qiu H, Yoshida T, Tsumori Y, Tsuge H.
    • Journal Title

      Acta Crystallogr F Struct Biol Commun.

      Volume: 70 Issue: 1 Pages: 72-75

    • DOI

      10.1107/s2053230x13032603

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Journal Article] Conformational Polymorphism of m(7)GTP in Crystal Structure of the PB2 Middle Domain from Human Influenza A Virus2013

    • Author(s)
      Tsurumura T, Qiu H, Yoshida T, Tsumori Y, Hatakeyama D, Kuzuhara T, Tsuge H.
    • Journal Title

      PLoS One

      Volume: 8(11)

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Journal Article] Crystal structures ofdye-decolorizing peroxidase with ascorbic acid and 2,6-dimethoxyphenol2012

    • Author(s)
      T. Yoshida, H. Tsuge, T. Hisabori, Y. Sugano
    • Journal Title

      FEBS Letters

      Volume: 586(24) Pages: 4351-4356

    • Data Source
      KAKENHI-PROJECT-22570136
  • [Journal Article] Crystal structure of dye-decolorizing peroxidase with ascorbic acid and 2,6-dimethoxyphenol2012

    • Author(s)
      T. Yoshida, H. Tsuge, T. Hisabori, Y. Sugano
    • Journal Title

      FEBS Letters

      Volume: 586 Pages: 4351-4356

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570136
  • [Journal Article] Structural basis of the free reduced flavin generation by flavin reductase from Thermus thermophilus HB82011

    • Author(s)
      Imagawa T, Tsurumura T, Sugimoto Y, Aki K, Ishidoh K, Kuramitsu S, Tsuge H
    • Journal Title

      J Biol Chem

      Volume: 286(51) Pages: 44078-85

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/22052907

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Structure and stability of Gyuba, β-lactoglobulin chimera2011

    • Author(s)
      Ohtomo H, Konuma T, Utsunomiya H, Tsuge H, Ikeguchi M
    • Journal Title

      Protein Sci

      Volume: 20(11) Issue: 11 Pages: 1867-75

    • DOI

      10.1002/pro.720

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121, KAKENHI-PUBLICLY-23121529
  • [Journal Article] The catalytic mechanism of dye-decolorizing peroxidase DyP may require theswinging movement of an aspartic acid residue2011

    • Author(s)
      T. Yoshida, H. Tsuge, H. Konno, T.Hisabori, Y. Sugano
    • Journal Title

      FEBS Journal

      Volume: 278(13) Pages: 2387-2394

    • Data Source
      KAKENHI-PROJECT-22570136
  • [Journal Article] Structural basis of free reduced flavin generation by flavin reductase from Thermus thermophilus HB82011

    • Author(s)
      Imagawa T, Tsurumura T, Sugimoto Y, Aki K, Ishidoh K, Kuramitsu S, Tsuge H
    • Journal Title

      J Biol Chem

      Volume: 286(51) Pages: 44078-44085

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Journal Article] The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue2011

    • Author(s)
      Yoshida T, Tsuge H, Konno H, Hisabori T, Sugano Y
    • Journal Title

      FEBS J

      Volume: 278(13) Pages: 2387-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue2011

    • Author(s)
      Yoshida T, Tsuge H, Konno H, Hisabori T, Sugano Y
    • Journal Title

      FEBS.J

      Volume: 278 Pages: 2387-2394

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Journal Article] Structural basis of free reduced flavin generation by flavin reductase from Thermus thermophilus HB82011

    • Author(s)
      Imagawa T, Tsurumura T, Sugimoto Y, Aki K, Ishidoh K, Kuramitsu S, Tsuge H
    • Journal Title

      J Biol Chem.

      Volume: 286(51) Pages: 44078-44085

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue2011

    • Author(s)
      Yoshida T, Tsuge H, Konno H, Hisabori T, Sugano Y
    • Journal Title

      FEBS.J

      Volume: 278 Pages: 2387-2394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Nucleolin as cell surface receptor for tumor necrosis factor-alpha inducing protein : a carcinogenic factor of Helicobacter pylori.2010

    • Author(s)
      Watanabe T, Tsuge H, Imagawa T, Kise D, Hirano K, Beppu M, Takahashi A, Yamaguchi K, Fujiki H, Suganuma M.
    • Journal Title

      J Cancer Res Clin Oncol.

      Volume: 136(6) Pages: 911-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Nucleolin as cell surface receptor for tumor necrosis factor-alpha inducing protein : a carcinogenic factor of Helicobacter pylori2010

    • Author(s)
      Watanabe T, Tsuge H, Imagawa T, Kise D, Hirano K, Beppu M, Takahashi A, Yamaguchi K, Fujiki H, Suganuma M
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 136(6) Pages: 911-21

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20049476

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Nucleolin as cell surface receptor for tumor necrosis factor-alpha inducing protein : a carcinogenic factor of Helicobacter pylori2010

    • Author(s)
      Watanabe T., Tsuge H., 等
    • Journal Title

      J Cancer Res Clin Oncol. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue2009

    • Author(s)
      Kuzuhara T, Kise D, Yoshida H, Horita T, Murazaki Y, Nishimura A, Echigo N, Utsunomiya H, Tsuge H
    • Journal Title

      J Biol Chem

      Volume: 284(11) Pages: 6855-60

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19144639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] The carboxy-terminal tail of Aeromonas sobria Serine Protease is associated with the chaperone2009

    • Author(s)
      Kobayashi H, Tateishi A, Tsuge H, Takahashi E, Okamoto K, Yamanaka H
    • Journal Title

      Microbiol Immunol

      Volume: 53(12) Pages: 647-57

    • NAID

      10027687949

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19954452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Structural basis for the Helicobacter pylori-carcinogenic TNF-alpha-inducing protein2009

    • Author(s)
      Tsuge H., Tsurumura T., 等
    • Journal Title

      Biochem Biophys Res Commun. 388-2

      Pages: 193-198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Crystallization and X-ray diffraction analysis of the RNA primer/promoter-binding domain of influenza A virus RNA-dependent RNA polymerase PB22009

    • Author(s)
      Kuzuhara T, Kise D, Yoshida H, Horita T, Murazaki Y, Utsunomiya H, Tsuge H
    • Journal Title

      Acta Crystallogr Sect F Struct Biol Cryst Commun

      Volume: 65 Pages: 144-6

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19194006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Crystallization and X-ray diffraction analysis of RNA-primer/promoter-binding domain of influenza A virus RNA-dependent RNA polymerase PB22009

    • Author(s)
      Tsuge H., Kuzuhara T., Kise D. et al.
    • Journal Title

      Acta Crystallographica sect F Struct Biol Cryst Commun 1-65

      Pages: 144-146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Crystallization and X-ray diffraction analysis of RNA-primer/promoter-binding domain of influenza A virus RNA-dependent RNA polymerase PB2.2009

    • Author(s)
      Kuzuhara T., Tsuge H., 等
    • Journal Title

      Acta Crystallographica sect F Struct Biol Cryst Commun. 1-65

      Pages: 144-146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] The carboxy-terminal tail of Aeromonas sobria serine protease is associated with the chaperone2009

    • Author(s)
      Kobayashi H., Tsuge H., 等
    • Journal Title

      Microbiol Immunol. 53-12

      Pages: 647-657

    • NAID

      10027687949

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Refolding, characterization and crystal structure of(S)-malate dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix2009

    • Author(s)
      Kawakami R, Sakuraba H, Goda S, Tsuge H, Ohshima T
    • Journal Title

      Biochim Biophys Acta

      Volume: 1794(10) Pages: 1496-504

    • NAID

      120007015445

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19555779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Clostridium perfringens Iota-Toxin : Structure and Function2009

    • Author(s)
      Sakurai J., Tsuge H., 等
    • Journal Title

      Toxins. 1

      Pages: 208-228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Structural basis for the kexin-like serine protease from Aeromonas sobria as sepsis-causing factor2009

    • Author(s)
      Kobayashi H, Utsunomiya H, Yamanaka H, Sei Y, Katunuma N, Okamoto K, Tsuge H
    • Journal Title

      J Biol Chem

      Volume: 284(40) Pages: 27655-63

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19954452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Structural basis for the Helicobacter pylori-carcinogenic TNF-alpha-inducing protein2009

    • Author(s)
      Tsuge H, Tsurumura T, Utsunomiya H, Kise D, Kuzuhara T, Watanabe T, Fujiki H, Suganuma M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 388(2) Pages: 193-8

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19643085

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Refolding characterization and crystal structure of(S)-malate dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix2009

    • Author(s)
      Kawakami R., Tsuge H., 等
    • Journal Title

      Biochim Biophys Acta. 1794-10

      Pages: 1496-1504

    • NAID

      120007015445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue.2009

    • Author(s)
      Kuzuhara T., Tsuge H., 等
    • Journal Title

      J Biol Chem. 284-11

      Pages: 6855-6860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Non-native alpha-helix formation is not necessary for folding of lipocalin : comparison of burst-phase folding between tear lipocalin and beta-lactoglobulin2009

    • Author(s)
      Tsukamoto S, Yamashita T, Yamada Y, Fujiwara K, Maki K, Kuwajima K, Matsumura Y, Kihara H, Tsuge H, Ikeguchi M
    • Journal Title

      Proteins

      Volume: 76(1) Pages: 226-36

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19137619

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue2009

    • Author(s)
      Tsuge H., Kuzuhara T., Kise D. et al.
    • Journal Title

      J Biol Chem 284-11

      Pages: 6855-6860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Structural analysis of human glutamine : fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes2009

    • Author(s)
      Nakaishi Y, Bando M, Shimizu H, Watanabe K, Goto F, Tsuge H, Kondo K, Komatsu M
    • Journal Title

      FEBS Lett

      Volume: 583(1) Pages: 163-7

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19059404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Structural basis for the kexin-like serine protease from Aeromonas sobria as a sepsiscausing factor2009

    • Author(s)
      Kobayashi H., Tsuge H., 等
    • Journal Title

      J Biol Chem. 284-40

      Pages: 27655-27663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Journal Article] Structure of an archaeal alanine:glyoxylate aminotransferase2008

    • Author(s)
      Tsuge H., Katunuma N., Sakuraba H. et al.
    • Journal Title

      Acta Crystallogr D Biol Crystallogr 64-6

      Pages: 696-699

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Crystal structure of the YdiC-family protein TTHBO29 from Thermus thermophilus HB8:Structural relationship with peptidoglycan N-acetylglucosamine deacetylase2008

    • Author(s)
      Tsuge H., Imagawa T., 等
    • Journal Title

      Biochem Biophys Res Commun 367-3

      Pages: 535-541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Structural basis of actin recognition and arginine ADP-ribosylation by Clostridium perfringens iota-toxin.2008

    • Author(s)
      Tsuge H., Nagahama M., 等
    • Journal Title

      Proc Natl Acad Sci U.S.A. 105-21

      Pages: 7399-7404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Crystal structure of the YdiC-family protein TTHB029 from Thermus thermophilus HB8:Structural relationship with peptidoglycan N-acetylglucosamine deacetylase2008

    • Author(s)
      Tsuge H., Imagawa T. et al.
    • Journal Title

      Biochem Biophys Res Commun 367-3

      Pages: 535-541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Structure of l-aspartate oxidase from the hyperthermophilic archaeon Sulfblobus tokodaii2008

    • Author(s)
      Tsuge H., Sakuraba H., 等
    • Journal Title

      Biochim Biophys Acta 1784-3

      Pages: 563-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes2008

    • Author(s)
      Tsuge H., Nakaishi Y., Bando M. et al.
    • Journal Title

      FEBS Lett 583-1

      Pages: 163-167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Structural analysis of human glutamine : fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes.2008

    • Author(s)
      Nakaishi Y., Tsuge H., 等
    • Journal Title

      FEBS Lett. 583-1

      Pages: 163-167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Non-native alpha-helix formation in not necessary for folding of lipocalin : Comparison of burst-phase folding between tear lipocalin and beta-lactoglobulin.2008

    • Author(s)
      Tsukamoto S., Tsuge H., 等
    • Journal Title

      Proteins. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Structure of 1-aspartate oxidase from the hyperthermophilic archaeon Sulfolobus tokodaii2008

    • Author(s)
      Tsuge H., Sakuraba H., Katunuma N. et al.
    • Journal Title

      Biochim Biophys Acta 1784-3

      Pages: 563-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Non-native alpha-helix formation in not necessary for folding of lipocalin:Comparison of burst-phase folding between tear lipocalin and beta-lactoglobulin2008

    • Author(s)
      Tsuge H., Tsukamoto S., Yamashita T. et al.
    • Journal Title

      Proteins (In press)

      Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Structure of an archaeal alanine : glyoxylate aminotransferase.2008

    • Author(s)
      Sakuraba H., Tsuge H., 等
    • Journal Title

      Acta Crystallogr D Biol Crystallogr. 64-6

      Pages: 696-699

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Structural basis of actin recognition and arginine ADP-ribosylation by Clostridium perfringens iota-toxin2008

    • Author(s)
      Tsuge H., Nagahama M., Oda M., Sakurai J. et al.
    • Journal Title

      Proc Natl Acad Sci U.S.A. 105-21

      Pages: 7399-7404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Crystal structure of archaeal highly thermostable L-aspartate dehydrogenase/NAD/citrate ternary complex2007

    • Author(s)
      Tsuge H., Yoneda K. et al.
    • Journal Title

      FEBS Journal 274-16

      Pages: 4315-4325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Sequential aldol condensation catalyzed by hyperthermophilic 2-deoxy-d-ribose-5-phosphate aldolase2007

    • Author(s)
      Tsuge H., Sakuraba H. et al.
    • Journal Title

      Appl Environ Microbiol 73-22

      Pages: 7427-7434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Crystal structure of archaeal highly thermostable L-aspartate dehydrogenase/NAD/citrate ternary complex2007

    • Author(s)
      Tsuge H., Yoneda K., 等
    • Journal Title

      FEBS Journal 274-16

      Pages: 4315-4325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Human D-amino acid oxidase: an update and review2007

    • Author(s)
      Tsuge H., Kawazoe T. et al.
    • Journal Title

      Chem Rec 7-5

      Pages: 305-315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Sequential aldol condensation catalyzed by hyperthermophilic 2-deoxy-d-ribose-5-phosphate aldolase2007

    • Author(s)
      Tsuge H., Sakuraba H., 等
    • Journal Title

      Appl Environ Microbiol 73-22

      Pages: 7427-7434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] Human D-amino acid oxidase:an update and review2007

    • Author(s)
      Tsuge H., Kawazoe T., 等
    • Journal Title

      Chem Rec 7-5

      Pages: 305-315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Journal Article] 新規ジフラビン脱水素酵素ファミリー:FAD,FMN,ATP結合L-プロリン脱水素酵素複合体の構造と機能2006

    • Author(s)
      津下英明, 等
    • Journal Title

      生化学 78・1

      Pages: 41-45

    • NAID

      10017148546

    • Data Source
      KAKENHI-PROJECT-17590256
  • [Journal Article] 新規ジフラビン脱水素酵素ファミリー : FAD, FMN, ATP結合L-プロリン脱水素酵素複合体の構造と機能2006

    • Author(s)
      津下英明, 等
    • Journal Title

      生化学 78・1

      Pages: 41-45

    • NAID

      10017148546

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590256
  • [Journal Article] Crystal Structure of a novel FAD-, FMN-, and ATP-containing L-Proline Dehydrogenase Complex from Pyrococcus horikoshii2005

    • Author(s)
      Tsuge H., et al.
    • Journal Title

      J Biol Chem. 280

      Pages: 31045-31049

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590256
  • [Journal Article] Crystal Structure of a novel FAD-, FMN-, and ATP-containing L-Proline Dehydrogenase Complex from Pyrococcus horikoshii2005

    • Author(s)
      Tsuge H., 等
    • Journal Title

      J Biol Chem. 280

      Pages: 31045-31049

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590256
  • [Journal Article] 新規ジフラビン脱水素酵素ファミリー : FAD, FMN, ATP結合L-プロリン脱水素酵素複合体の構造と機能2005

    • Author(s)
      津下英明, 等
    • Journal Title

      生化学

      Pages: 41-45

    • NAID

      10017148546

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590256
  • [Presentation] 電気生理による二成分毒素のポアシグナル測定2023

    • Author(s)
      三谷優季、川野竜司、滝口創太郎、津下英明
    • Organizer
      第69回トキシンシンポジウム
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] ウェルシュ菌イオタ毒素の膜透過機構の研究2023

    • Author(s)
      迫田憲亮、山田等仁、津下英明
    • Organizer
      第69回トキシンシンポジウム
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] Ribosome -Inactivating Proteinのリボソーム特異性と抗ウイルス活性に関する研究2023

    • Author(s)
      羽深典之、津下英明
    • Organizer
      第69回トキシンシンポジウム
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] スクミリンゴガイの膜孔形成毒素, PcPv-2オリゴマー構造の撮影の試み2023

    • Author(s)
      西田和哉、山田等仁、津下英明
    • Organizer
      第69回トキシンシンポジウム
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] クライオ電子顕微鏡から見えてきたウェルシュ菌イオタ毒素の膜孔形成機構2023

    • Author(s)
      山田等仁、杉田征彦、野田岳志、津下英明
    • Organizer
      第69回トキシンシンポジウム
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] ウェルシュ菌イオタ毒素Ib serine-clamp変異体の単粒子構造解析及び活性測定2023

    • Author(s)
      三谷優季、津下英明
    • Organizer
      第23回蛋白質科学会
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] 細菌ADPリボシル化酵素の基質認識機構とその細胞膜透過に関する研究2023

    • Author(s)
      津下英明
    • Organizer
      第75回日本ビタミン学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] 二成分毒素:ADPリボシル化酵素成分の基質認識機構と細胞膜透過機構について2023

    • Author(s)
      津下英明
    • Organizer
      日本環境変異原ゲノム学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] スクミリンゴガイ(Pomacea canaliculata)卵塊のタンパク質の物性2023

    • Author(s)
      津下英明
    • Organizer
      第473回ビタミンB 研究協議会
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] 二成分毒素CPILEbのセリンで形成された膜貫通孔2023

    • Author(s)
      吉田徹、門間千枝、滝口創太郎、藤田祥子、内田悠斗、山田等仁、川野竜司、津下英明
    • Organizer
      第69回トキシンシンポジウム
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] Construction of a membrane translocation assay system for C. difficile binary toxin by electrophysiological technique2023

    • Author(s)
      Yuki Mitani, Sotaro Takiguchi, Ryuji Kawano, Hideaki Tsuge
    • Organizer
      第60回日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] C. perfringens 由来に成分毒素CPILEbの貫通膜孔は、セリンで形成された最狭窄部位をもつ2022

    • Author(s)
      吉田徹、内田悠斗、山田等仁、津下英明
    • Organizer
      第68回トキシンシンポジウム (オンライン)
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] C. perfringens 由来に成分毒素CPILEbの貫通膜孔は、セリンで形成された最狭窄部位をもつ2022

    • Author(s)
      吉田徹、内田悠斗、山田等仁、津下英明
    • Organizer
      第68回トキシンシンポジウム
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] スクミリンゴガイ膜孔形成毒素PcPV-2の構造と機能の解析2022

    • Author(s)
      西田和哉、山田等仁、津下英明
    • Organizer
      第68回トキシンシンポジウム
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] スクミリンゴガイ膜孔形成毒素PcPV-2の構造と機能の解析2022

    • Author(s)
      西田和哉、山田等仁、津下英明
    • Organizer
      第68回トキシンシンポジウム (オンライン)
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] クライオ電子顕微鏡による高分解能構造解析で明らかになってきた二成分毒素の膜透過機構2022

    • Author(s)
      山田等仁、杉田征彦、野田岳志、津下英明
    • Organizer
      第60回生物物理学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] ディフィシル菌が産生する二成分毒素の構造解析2022

    • Author(s)
      山田等仁、川本晃大、吉田徹、加藤貴之、津下英明
    • Organizer
      第68回トキシンシンポジウム
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] Effect of narrowest clamp of binary toxin on cell toxicity2022

    • Author(s)
      内田悠斗、吉田徹、山田等仁、津下英明
    • Organizer
      第60回生物物理学会
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] イオタ毒素Ia-GFPキメラのタンパク質膜透過の確認と構造解析2022

    • Author(s)
      友田駿、山田等仁、津下英明
    • Organizer
      第60回生物物理学会
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] クライオ電子顕微鏡によるディフィシル菌二成分毒素CDTa CDTb複合体の構造解析2022

    • Author(s)
      山田等仁、川本晃大、吉田徹、加藤貴之、津下英明
    • Organizer
      第22回日本蛋白質科学会
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] ディフィシル菌の二成分毒素のタンパク質膜透過の動的な様子2022

    • Author(s)
      山田等仁、吉田徹、津下英明
    • Organizer
      第469回ビタミンB 研究委員会
    • Data Source
      KAKENHI-PROJECT-21H02452
  • [Presentation] Diarrheagenic activity of each component of CPILE as a new enterotoxin produced by Clostridium perfringens isolated from foodborne outbreaks2019

    • Author(s)
      Monma C, Saiki D, Shimojima Y, Suzuki J, Sadamasu K, Yamada T, Tsuge H, Kamata Y
    • Organizer
      CLOSPATH 11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] Clostridium Binary Toxin:膜孔形成タンパク質トロンスロコンの作用機構について2019

    • Author(s)
      津下英明
    • Organizer
      京都薬科大学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] Cryo-EM structure of clostridial binary toxin translocon Ib-pore2019

    • Author(s)
      Yamada T, Yoshida T, Kawamoto A, Mitsuoka K, Iwasaki K, and Tsuge H
    • Organizer
      European Workshops on Bacterial Protein Toxins - ETOX19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] ウェルシュ菌2成分毒素 膜孔複合体の単粒子解析2019

    • Author(s)
      山田等仁、津下英明
    • Organizer
      生理研研究会 クライオ電子顕微鏡によるタンパク質の高分解能単粒子構造解析~みんなのクライオ電顕~
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] タンパク質膜透過チャネルの単粒子構造解析2019

    • Author(s)
      津下英明
    • Organizer
      第453回ビタミンB 研究協議会
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] Cryo-EM structure of clostridial binary toxin translocation channel Ib-pore2019

    • Author(s)
      山田等仁、吉田徹、川本暁大、光岡薫、岩崎憲司、津下英明
    • Organizer
      第57回日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] From Protein to DNA Modification: Substrate recognition mechanism in pierisin family DNA-targeting guanine-specific ADP-ribosyltransferase ScARP2018

    • Author(s)
      津下英明
    • Organizer
      日本分子生物学会 ワークショップADP-ribosylation in intra- & extracellular communication and diseases
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] DNAを標的としたADPリボシル化酵素の基質認識機構2018

    • Author(s)
      津下英明
    • Organizer
      第453回ビタミンB 研究協議会
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] Membrane transport and ADP-ribosylation mechanism of binary toxin C. perfringens iota toxin2018

    • Author(s)
      Yoshida T, Yamada T, and Tsuge H
    • Organizer
      International Symposium on “Proteins; from the Cradle to the Grave”
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] Cryo-EM single particle analysis of C. perfringens binary toxin2018

    • Author(s)
      Yamada T, Yoshida T, and Tsuge H
    • Organizer
      International Symposium on “Proteins; from the Cradle to the Grave”
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] Substrate recognition and reaction mechanism of DNA-targeting guanine-specific ADP-ribosyltransferase2018

    • Author(s)
      Yoshida T, and Tsuge H
    • Organizer
      International Symposium on “Proteins; from the Cradle to the Grave”
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06170
  • [Presentation] Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin2017

    • Author(s)
      Waraphan Toniti, Toru Yoshida, Toshiharu Tsurumura, Daisuke Irikura, Chie Monma, Youichi Kamata, Hideaki Tsuge
    • Organizer
      ETOX18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] ウェルシュ菌の食中毒に関わる新規ADPリボシル化毒素CPILE:Iota毒素との比較2017

    • Author(s)
      津下英明
    • Organizer
      第447回ビタミンB 研究協議会
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] ヒトADPリボシル化酵素(PARP) と細菌モノADPリボシル化毒素との構造と機能の比較2017

    • Author(s)
      津下英明
    • Organizer
      第450回ビタミンB 研究協議会
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] Structure determination of Clostridium perfringens iota-like enterotoxin by X-ray crystallography2017

    • Author(s)
      Toru Yoshida, Hidetomo Kobayashi, Hiroyasu Yamanaka, Hideaki Tsuge
    • Organizer
      ETOX18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] Characterization of Actin ADP-ribosyltransferase from Clostridium perfringens iota-like enterotoxin2016

    • Author(s)
      Waraphan Toniti, Toru Yoshida, Toshiharu Tsurumura, Daisuke Irikura, Chie Monma, Yoichi Kamata, and Hideaki Tsuge
    • Organizer
      ICC05-AEM2016
    • Place of Presentation
      宇奈月国際会館(富山)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] ADPリボシル化毒素C3がシグナル伝達阻害を引き起こすしくみ2016

    • Author(s)
      津下英明
    • Organizer
      日本細菌学会
    • Place of Presentation
      大阪国際交流センター(大阪府、大阪市)
    • Year and Date
      2016-03-23
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] ADP-ribosylation of RhoA by C3 exoenzyme.2016

    • Author(s)
      Toru Yoshida, and Hideaki Tsuge
    • Organizer
      ICC05-AEM2016
    • Place of Presentation
      宇奈月国際会館(富山)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] C3 exoenzymeとRhoA複合体の結晶構造解析に基づく基質特異性2016

    • Author(s)
      津下英明、戸田暁之、鶴村俊治、吉田徹
    • Organizer
      日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] Structural basis of ADP-ribosyltransferase C3 exoenzyme with RhoA complex2015

    • Author(s)
      戸田暁之、鶴村俊治、吉田徹、津守耶良、津下英明
    • Organizer
      日本生物物理学会
    • Place of Presentation
      金沢大学(石川県、金沢市)
    • Year and Date
      2015-09-13
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] Structural basis of Bacterial ADP-ribosyltransferase and Human Protein Complex2015

    • Author(s)
      Hideaki Tsuge
    • Organizer
      European Workshop on Bacterial Protein Toxins
    • Place of Presentation
      Braga, Portugal
    • Year and Date
      2015-06-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08289
  • [Presentation] ADPリボシル化RhoAの立体構造に基づく阻害機構2014

    • Author(s)
      津下英明
    • Organizer
      ビタミンB研究協議会
    • Place of Presentation
      大阪工業大学うめきたナレッジセンター
    • Year and Date
      2014-11-22
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Presentation] 細菌感染症因子とホストタンパク質複合体の構造生物学2014

    • Author(s)
      津下英明
    • Organizer
      第7回共同利用・共同研究「酵素学研究拠点」シンポジウム
    • Place of Presentation
      徳島大学疾患酵素学研究センター(徳島)
    • Year and Date
      2014-11-14
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Presentation] 分解能決定におけるCChalf とR 値の関係性の考察2013

    • Author(s)
      江村晃太・吉田徹・津下英明
    • Organizer
      日本結晶学会
    • Place of Presentation
      熊本大学(熊本)
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Presentation] インンフルエンザウィルスRNAポリメラーゼ CAP結合とその構造2013

    • Author(s)
      鶴村俊治、秋こう、吉田徹、津守耶良、津下英明
    • Organizer
      ビタミンB研究協議会
    • Place of Presentation
      ウインクあいち(名古屋)
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Presentation] 沈澱剤フリー高濃度リゾチーム溶液からの結晶成長2013

    • Author(s)
      鈴木良尚, 津下英明, 上田昭子, 細川晃平
    • Organizer
      第43回結晶成長国内会議
    • Place of Presentation
      長野市生涯学習センター(長野県)
    • Year and Date
      2013-11-06
    • Data Source
      KAKENHI-PROJECT-24656016
  • [Presentation] Application of iota-toxin and actin complex crystal as the ADP-ribosylation reaction chamber2013

    • Author(s)
      T.Tsurumura and H.Tsuge
    • Organizer
      International Symposium on Diffraction Structural Biology(ISDSB)
    • Place of Presentation
      吹上ホール(名古屋)
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Presentation] ATPase,GTPaseを標的とした細菌毒素による翻訳後修飾の構造生物学2013

    • Author(s)
      津下英明
    • Organizer
      日本女子大学「理学セミナー」
    • Place of Presentation
      日本女子大学(東京)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Presentation] Substrate Selectivity of Monoacylglycerol Lipase based on the Crystal Structure2013

    • Author(s)
      T.Tsurumura and H.Tsuge
    • Organizer
      Structural Life Science 7th International Conference on Structural Genomics
    • Place of Presentation
      京王プラザホテル(札幌)
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Presentation] 感染症を理解するための構造生物学2013

    • Author(s)
      津下英明
    • Organizer
      細菌学会
    • Place of Presentation
      浦安
    • Year and Date
      2013-03-18
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] アルギニンADPリボシル化初めての可視化2012

    • Author(s)
      津下英明
    • Organizer
      ビタミンB研究協議会
    • Place of Presentation
      京都
    • Year and Date
      2012-11-17
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] ADPリボシル化反応に伴う酵素の構造変化2012

    • Author(s)
      津下英明
    • Organizer
      ビタミンB研究協議会
    • Place of Presentation
      京都国際交流会館
    • Year and Date
      2012-02-04
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] ADPリボシル化反応に伴う酵素の構造変化2012

    • Author(s)
      津下英明
    • Organizer
      ビタミンB研究協議会
    • Place of Presentation
      京都国際交流会館
    • Year and Date
      2012-02-04
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] Actin Recognition and ADP-ribosylation of C. perfringens iota-toxin2012

    • Author(s)
      Hideaki Tsuge
    • Organizer
      The 11th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路
    • Year and Date
      2012-09-13
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] ADPリボシル化毒素構造研究の最前線2011

    • Author(s)
      津下英明
    • Organizer
      シンポジウム「疾患治療に用いる天然有機化合物の生合成遺伝子の包括的理解」
    • Place of Presentation
      徳島文理大学(招待講演)
    • Year and Date
      2011-12-22
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] アクチンADPリボシル化の構造基盤2011

    • Author(s)
      津下英明
    • Organizer
      シンポジウム「ADPリボシル化によるシグナル伝達制御」生化学会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] アクチンADPリボシル化の構造基盤2011

    • Author(s)
      津下英明
    • Organizer
      生化学会
    • Place of Presentation
      京都国際会館(招待講演)
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] ADPリボシル化毒素構造研究の最前線2011

    • Author(s)
      津下英明
    • Organizer
      シンポジウム「疾患治療に用いる天然有機化合物の生合成遺伝子の包括的理解」
    • Place of Presentation
      徳島文理大学
    • Year and Date
      2011-12-22
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] Structural basis for the Helicobacter pylori-carcinogenic TNF-alpha-inducing protein2011

    • Author(s)
      Tsurumura T., Tsuge H
    • Organizer
      国際結晶学会
    • Place of Presentation
      国際結晶学会Madrid
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] ADPリボシル化毒素構造研究の最前線2011

    • Author(s)
      津下英明
    • Organizer
      シンポジウム「疾患治療に用いる天然有機化合物の生合成遺伝子の包括的理解」
    • Place of Presentation
      徳島文理大学(招待講演)
    • Year and Date
      2011-12-22
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] Crystal structure of Ia-Actin complex with novel ligand2011

    • Author(s)
      Tsurumura T., Tsuge H.
    • Organizer
      IUCr(国際結晶学会)
    • Place of Presentation
      Madrid Spain
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] ADPリボシル化毒素によるアクチン認識の特異性解析2011

    • Author(s)
      鶴村俊治、津下英明
    • Organizer
      日本蛋白質科学会
    • Place of Presentation
      大阪府吹田市
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] 感染症因子とヒトタンパク質の相互作用を見る2011

    • Author(s)
      津下英明
    • Organizer
      X線の会
    • Place of Presentation
      阪急グランドビル(招待講演)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] アクチンADPリボシル化の構造基盤2011

    • Author(s)
      津下英明
    • Organizer
      生化学会
    • Place of Presentation
      京都国際会館(招待講演)
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] ADPリボシル化毒素によるアクチン認識の特異性解析2011

    • Author(s)
      鶴村俊治、津下英明
    • Organizer
      日本蛋白質科学会
    • Place of Presentation
      大阪府吹田市
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] Structural basis for the Helicobacter pylori-carcinogenic TNF-alpha-inducing protein2011

    • Author(s)
      Tsurumura T., Tsuge H.
    • Organizer
      IUCr,(国際結晶学会)
    • Place of Presentation
      Madrid Spain
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] Structural basis for the Helicobacter pylori-carcinogenic TNF-alpha-inducing protein2011

    • Author(s)
      Tsurumura T., Tsuge H.
    • Organizer
      IUCr,(国際結晶学会)
    • Place of Presentation
      Madrid Spain
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] Crystal structure of Ia-Actin complex with novel ligand2011

    • Author(s)
      Tsurumura T., Tsuge H
    • Organizer
      国際結晶学会
    • Place of Presentation
      Madrid
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] 感染症因子とヒトタンパク質の相互作用を見る2011

    • Author(s)
      津下英明
    • Organizer
      X線の会
    • Place of Presentation
      阪急グランドビル(招待講演)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PUBLICLY-23121529
  • [Presentation] Crystal structure of Ia-Actin complex with novel ligand2011

    • Author(s)
      Tsurumura T., Tsuge H.
    • Organizer
      IUCr(国際結晶学会)
    • Place of Presentation
      Madrid Spain
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] 感染症因子とヒトタンパク質の相互作用を見る2011

    • Author(s)
      津下英明
    • Organizer
      X線の会
    • Place of Presentation
      阪急グランドビル26階
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] モノADPリボシル化毒素とその標的タンパク質アクチンとの複合体のX線結晶構造解析2010

    • Author(s)
      津下英明
    • Place of Presentation
      国立がんセンター研究所
    • Year and Date
      2010-02-22
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] 「X線結晶構造解析と質量分析による生理活性タンパク質の構造機能相関の研究」『細菌およびウィルス感染症の構造生物学』2010

    • Author(s)
      津下英明
    • Organizer
      第4回学術フロンティアシンポジウム
    • Place of Presentation
      徳島文理大学 徳島校 (徳島市)
    • Year and Date
      2010-01-30
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] 細菌およびウィルス感染症の構造生物学2010

    • Author(s)
      津下英明
    • Organizer
      第4回学術フロンティアシンポジウム「X線結晶構造解析と質量分析による生理活性蛋白質の構造機能相関の研究」
    • Place of Presentation
      徳島文理大学
    • Year and Date
      2010-01-30
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] 高度好熱菌HB8由来のフラビン還元酵素の構造機能解析ビタミンB研究委員会2010

    • Author(s)
      今川貴仁、津下英明
    • Organizer
      第422回研究協議会
    • Place of Presentation
      京都市
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] 「X 線結晶構造解析と質量分析による生理活性タンパク質の構造機能相関の研究」『アルギニン特異的ADP リボシル化毒素とアクチン複合体のX線結晶構造解析』2009

    • Author(s)
      津下英明
    • Organizer
      第3 回学術フロンティアシンポジウム
    • Place of Presentation
      徳島文理大学徳島校(徳島市)
    • Year and Date
      2009-02-28
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue2009

    • Author(s)
      Kuzuhara T., Tsuge H.
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      アスティとくしま(徳島市)
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] Crystal structure of influenza virus RNA polymerase PB2 including host determinant residue K6272009

    • Author(s)
      津下英明
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      アスティとくしま(徳島市)
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] インフルエンザウィルスRNAポリメラーゼPB2のX線結晶構造解析2009

    • Author(s)
      津下英明
    • Organizer
      第416回ビタミンB研究協議会
    • Place of Presentation
      京都学園大学(京都府亀岡市)
    • Year and Date
      2009-05-29
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] 「X線結晶構造解析と質量分析による生理活性タンパク質の構造機能相関の研究」『アルギニン特異的ADPリボシル化毒素とアクチン複合体のX線結晶構造解析』2009

    • Author(s)
      津下英明
    • Organizer
      第3回学術フロンティアシンポジウム
    • Place of Presentation
      徳島文理大学徳島校(徳島市)
    • Year and Date
      2009-02-28
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Structural Basis of influenza A virus RNA polymerase PB2 domain including pathogenicity determinant residue K6272009

    • Author(s)
      Tsuge H.
    • Organizer
      21^<th> IUBMB & 12^<th> FAOBMB International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai, CHINA
    • Data Source
      KAKENHI-PROJECT-21570121
  • [Presentation] 「X線結晶構造解析と質量分析による生理活性タンパク質の構造機能相関の研究」『複合体タンパク質X線結晶構造から見る酵素反応機能』2008

    • Author(s)
      津下 英明
    • Organizer
      徳島文理大学・健康科学研究所私学助成研究発表会
    • Place of Presentation
      徳島文理大学徳島校(徳島市)
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] 「X 線結晶構造解析と質量分析による生理活性タンパク質の構造機能相関の研究」『複合体タンパク質X 線結晶構造から見る酵素反応機能』2008

    • Author(s)
      津下英明
    • Organizer
      徳島文理大学・健康科学研究所・私学助成研究発表会
    • Place of Presentation
      徳島文理大学 徳島校(徳島市)
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Aeromonas sobriaセリンプロテアーゼの結晶構造構造解析2008

    • Author(s)
      津下英明
    • Organizer
      日本生物物理学会第1回中国四国支部大会
    • Place of Presentation
      高知大学朝倉キャンパス(高知市)
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] アルギニン特異的ADP リボシル化毒素とアクチン複合体のX線結晶構造解析2008

    • Author(s)
      津下英明
    • Organizer
      北海道大学生体高分子シンポジウム
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2008-12-19
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] -タンパク質・ペプチド研究の現状と展望-「アルギニン特異的ADPリボシル化毒素とアクチン複合体のX線結晶構造解析」2008

    • Author(s)
      津下英明
    • Organizer
      第18回WSフォーラム和光純薬工業(株)福岡営業所
    • Place of Presentation
      九州大学医系地区コラボセンクー(福岡市)
    • Year and Date
      2008-11-21
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Novel Family of Diflavin Enzyme : Crystal Structure of Archaeal L-Proline Dehydrogenase and the Industrial Application.2008

    • Author(s)
      Tsuge H.
    • Organizer
      BIT's 1^<st> Annual World Congress of ibio 2008
    • Place of Presentation
      New Century Grand Hotel Hangzhou, China
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Novel Family of Diflavin Enzyme:Crystal Structure of Archaeal L-Proline Dehydrogenase and the Industrial Application2008

    • Author(s)
      Tsuge H.
    • Organizer
      BIT's 1^<st> Annual World Congress of ibio 2008
    • Place of Presentation
      New Century Grand Hotel Hangzhou, China
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] -タンパク質・ペプチド研究の現状と展望-「アルギニン特異的ADP リボシル化毒素とアクチン複合体のX線結晶構造解析」2008

    • Author(s)
      津下英明
    • Organizer
      第18 回WS フォーラム 和光純薬工業(株)福岡営業所
    • Place of Presentation
      九州大学医系地区コラボセンター(福岡市)
    • Year and Date
      2008-11-21
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] アルギニン特異的ADPリボシル化毒素とアクチン複合体のX線結晶構造解析2008

    • Author(s)
      津下英明
    • Organizer
      北海道大学生体高分子シンポジウム
    • Place of Presentation
      北海道大学(北海道)
    • Year and Date
      2008-12-19
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Aeromonas sobria セリンプロテアーゼの結晶構造解析2008

    • Author(s)
      津下英明, 宇都宮敬子 等
    • Organizer
      日本生物物理学会第1 回中国四国支部大会
    • Place of Presentation
      高知大学朝倉キャンパス(高知市)
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] ADPリボシル化酵素とフラビン酵素の構造機能相関2007

    • Author(s)
      津下 英明
    • Organizer
      第410回ビタミンB研究協議会
    • Place of Presentation
      京大会館(京都市)
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Substrate recognition of ADP-ribosylating toxins2007

    • Author(s)
      Tsuge H.
    • Organizer
      Brookhaven National Laboratory
    • Place of Presentation
      New York
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Crystal structure of the YdiC family protein TTHB029 from Thermus thermos thermophilus HB8 revealed structural similarity with peptidoglycan deacetylase2007

    • Author(s)
      Tsuge H., Imagawa T. et al.
    • Organizer
      ISDSB2007(The 2^<nd> International Symposium on Diffraction Structure Biology 2007)
    • Place of Presentation
      Tower Hall Funabori, Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Crystallographic Study of Human D-Amino Acid Oxidase:Structural Basis of D-DOPA Oxidation2007

    • Author(s)
      Tsuge H., Kawazoe T., Fukui K.
    • Organizer
      THE 21^<st> SYMPOSIUM OF THE PROTEIN SOCIETY
    • Place of Presentation
      Boston, Massachusetts
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Crystal structure of Aeromonas sobria serine protease, prototype kexin/furin protease:the extra occluding domain regulates protein substarte specificity2007

    • Author(s)
      Tsuge H., Kobayashi H. et al.
    • Organizer
      5^<th> General Meeting of the International Proteolysis Society(IPS2007)
    • Place of Presentation
      Patras, Greece
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] アルギニンADPリボシル化の毒素のアクチン認識分子機構2007

    • Author(s)
      津下英明, 小田真隆, 櫻井純 等
    • Organizer
      第45 回日本生物物理学会年会
    • Place of Presentation
      パシフィコ横浜会議センター(横浜市)
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Crystallographic Study of Human D-Amino Acid OXidase:Structural Basis of D-DOPA OXidation2007

    • Author(s)
      Tsuge H., Kawazoe T., Fukui K
    • Organizer
      THE 21st SYMPOSIUM OF THE PROTEIN SOCIETY
    • Place of Presentation
      Boston,Massachusetts
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Crystal structure of the YdiC famiy protein TTHBO29 from Thermus the rmos thermophjlus HB8 revealed structural sirnilarity with peptidogly can deacetylase2007

    • Author(s)
      Tsuge H., Imagawa T., 等
    • Organizer
      ISDSB2007(The2nd International Symposium on Diffraction Structure Biology2007)
    • Place of Presentation
      Tower Hall Funabori,Tokyo,Japan
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Crystal structure of Aeromonas sobria serine protease,prototype kexin/furin protease:the extra occluding domain regUlates protein substarte specificity2007

    • Author(s)
      Tsuge H., Kobayashi H., 等
    • Organizer
      5th General Meeting of the International Proteolysis Society(IPS2007)
    • Place of Presentation
      Patras,Greece
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] Substrate recognitio of ADP-ribosylating toxins2007

    • Author(s)
      Tsuge H
    • Organizer
      Brookhaven National Laboratory
    • Place of Presentation
      New York
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] ADP リボシル化酵素とフラビン酵素の構造機能相関2007

    • Author(s)
      津下英明
    • Organizer
      第410 回ビタミンB 研究協議会
    • Place of Presentation
      京大会館(京都市)
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] アルギニンADPリボシル化の毒素のアクチン認識分子機構2007

    • Author(s)
      津下 英明、小田 真隆、櫻井 純, 等
    • Organizer
      第45回日本生物物理学会年会
    • Place of Presentation
      パシフィコ横浜会議センター(横浜市)
    • Data Source
      KAKENHI-PROJECT-19570113
  • [Presentation] ADPリボシル化RhoAの構造とそのシグナル伝達への影響

    • Author(s)
      戸田暁之、江村晃太、吉田徹、津守耶良、鶴村俊治、津下英明
    • Organizer
      日本生化学会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PUBLICLY-25121733
  • [Presentation] 沈澱剤フリー高濃度リゾチーム溶液からの結晶成長

    • Author(s)
      鈴木良尚, 津下英明, 上田昭子, 細川晃平
    • Organizer
      第43回結晶成長国内会議
    • Place of Presentation
      長野市生涯学習センター (長野県)
    • Data Source
      KAKENHI-PROJECT-24656016
  • 1.  KATUNUMA Nobuhiko (50035375)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 2.  YOSHIDA Toru (30724546)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 18 results
  • 3.  SAKURAI Jun (80029800)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 4.  SUGANO Yasushi (90282855)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 5.  NAGAHAMA Masahiro (40164462)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  ODA Masataka (00412403)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 7.  TSURUMURA Toshiharu (50450250)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 8.  SUZUKI Yoshihisa (60325248)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  SAKURABA Haruhiko (90205823)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OHKURA Kazuto (00242850)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HORI Hitoshi (90119008)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KITA Keiko (70234226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SAKO Yoshihiko (60153970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KOBAYASHI K. (90170315)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MIYANO Masashi (80332287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  AGO Hideo (70360477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  IKEGUCHI Masamichi (00192477)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  野村 紀通 (10314246)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  川野 竜司 (90401702)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 20.  杉田 征彦 (00734469)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TONITI WARAPHAN
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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