Nomura Norimichi 野村紀通

… Alternative Names

Researcher Number	10314246
Other IDs
External Links
Affiliation (Current)	2022: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 京都大学, 医学研究科, 准教授 2016 – 2018: 京都大学, 医学研究科, 助教 2017: 京都大学, 大学院医学研究科, 助教 2012 – 2015: 京都大学, 医学(系)研究科(研究院), 助教 2014: 京都大学, 大学院医学研究科, 助教 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Applied molecular and cellular biology / Structural biochemistry / Applied molecular and cellular biology / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related Except Principal Investigator Fisheries chemistry / General medical chemistry / Structural biochemistry / Fisheries chemistry / Applied microbiology / Complex systems / Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 43030:Functional biochemistry-related
Keywords	Principal Investigator 古細菌 / 超好熱菌 / ホーミングエンドヌクレアーゼ / 可動性イントロン / 逆遺伝学 / 遺伝子破壊 / イントロン / ホーミング / ゲノム / ゲノム多型 … More Except Principal Investigator X線結晶構造解析 / 結晶構造解析 / 古細菌 / ホーミングエンドヌクレアーゼ / 超好熱菌 / 創薬 / 抗体 / 膜タンパク質 / ゲノム / 制限修飾系 / 耐熱性酵素 / GPCR / トランスポーター / Archaea / エンドヌクレアーゼ / 構造生物学 / シグナル伝達 / ゲノム多型 / イントロンホーミング / 遺伝子水平伝播 / 利己的遺伝子 / 可動性イントロン / 有用遺伝子資源 / II型制限酵素 / タンパク質-DNA相互作用 / バイオインフォマテイックス / 無細胞蛋白質合成系 / モノクローナル抗体 / 立体構造認識抗体 / アデノシンA2a受容体 / 膜輸送体 / 輸送体 / 海底熱水孔 / 耐熱酵素 / 水素細菌 / イントロン / プロテアーゼ / 好熱遺伝子群 / 好気性超好熱菌 / 分子系統解析 / hyperthermophilic microorganism / marine hydrothermal vent / heat stable enzymes / homing endonuclease / hydrogen bacteria / Intron / restriction enzyme / 深海熱水環境 / 遺伝子資源 / ヒドロゲナーゼ / など / ヌクレアーゼ / 深海熱水孔 / ホーミングエンドヌクレアー / 海底熱水口 / 有用ゲノム資源 / メタゲノム解析 / 環境バイオテクノロジー / 知的財産権 / deep sea hydrothermal environment / hyperthermophilles / genome / genetic resources / thermostable enzyme / hydrogenase / endonuclease / 制限酵素 / タンパク質工学 / 特異性改変 / DNA結合タンパク質 / 結晶化 / 部位特異的変異 / 金属イオン / 界面活性剤 / 転写制御因子 / DNA認識機構 / Restriction endonuclease / Protein engineering / Alteration of substrate specificity / DNA-binding protein / Crystal structure analysis / ヒト膜受容体 / 薬剤開発 / ナルコレプシー / 睡眠 / 機能性抗体 / Gタンパク質共役型受容体 / タンパク質 / G蛋白質共役型受容体 / 蛋白質 / 癌 / X線自由電子レーザー / 構造ダイナミクス / 光遺伝学 / フォトクロミックタンパク質 / チャネルロドプシン / 時分割X線結晶構造解析 / 中分子 / クライオ電子顕微鏡単粒子解析 / 創薬ターゲット / 中分子ペプチド / ファージディスプレイ / 薬剤排出 / 物質輸送 / 多剤排出トランスポーター / 病原性細菌 / 薬剤排出トランスポーター / 構造解析 / 再構成 / 病原菌 / 薬剤耐性 / 膜輸送 Less

Time-resolved XFEL crystallography and rational engineering of light-driven proteins
- Principal Investigator
  
  岩田想
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
ヒト膜タンパク質を標的とした中分子構造創薬研究の基盤構築
- Principal Investigator
  
  岩田想
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kyoto University
MFS型多剤排出輸送体の多剤認識と輸送機構の解明
- Principal Investigator
  
  田辺幹雄
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  High Energy Accelerator Research Organization
Creation and crystallographic studies of artificial medium-sized aptamers that modulate membrane protein functionsPrincipal Investigator
- Principal Investigator
  
  Nomura Norimichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kyoto University
Crystallographic study of the mammalian bile acid transporter NTCP in complex with its conformation-specific antibodiesPrincipal Investigator
- Principal Investigator
  
  Nomura Norimichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Differential analysis of the crystal structures of active / inactive orexin receptor contributing to rational development of sleep control drug
- Principal Investigator
  
  Suno Ryoji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Trial for determining the structure of CXCR7
- Principal Investigator
  
  Shimamura Tatsuro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Structure determination of human membrane transporters
- Principal Investigator
  
  SHIMAMURA Tatsuro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Technologicaldevelopment for construction of synthetic proteins that facilitate membrane protein crystallizationPrincipal Investigator
- Principal Investigator
  
  NOMURA Norimichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Development of antibody stabilizing active or inactive state of GPCRs.
- Principal Investigator
  
  KOBAYASHI Takuya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
古細菌ゲノムに散在する可動性イントロンの集団内伝播と進化のダイナミクスPrincipal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ゲノム工学技術への応用をめざした人工レアカッター酵素の開発と分子設計原理の解明Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
Large scale collection and their industrial application of hyperthemophilic archaeal genome from deep sea hydrothermal envirenments
- Principal Investigator
  
  SAKO Yoshihiko
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kyoto University
Structural analysis of endonuclease-DNA interaction and alteration of substrate specificity
- Principal Investigator
  
  KITA Keiko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Kyoto University
古細菌ゲノムに散在する可動性イントロンの集団内伝播と進化のダイナミクスPrincipal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
海洋性好熱古細菌における新規制限酵素遺伝子群の網羅的開発に関する研究
- Principal Investigator
  
  SAKO Yoshihiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kyoto University
古細菌における制限酵素遺伝子群のゲノム規模での網羅的単離・同定Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
古細菌ゲノムの体系的・網羅的機能解析を支援する逆遺伝学的方法論の開発Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
古細菌ゲノムの体系的・網羅的機能解析を支援する逆遺伝学的方法論の開発Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
超好熱古細菌ゲノムの体系的機能解析のための分子遺伝学的基盤の構築Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
Isolation of novel thermophilic organisms from marine hydrothermal environments and the development of new catalytic functions
- Principal Investigator
  
  SAKO Yoshihiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  KYOTO UNIVERSITY

All 2021 2020 2019 2018 2017 2016 2015 2012 2011 2010 2007 2005

All Journal Article Presentation Book Patent

[Book] “The Intervening Removable Affinity Tag (iRAT) System for the Production of Recombinant Antibody Fragments” in Methods Mol Biol.2021
- Author(s)
  *Nomura N, Nomura Y, Sato Y and *Iwata S.
- Total Pages
  340
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-18K05334
[Book] “The Intervening Removable Affinity Tag (iRAT) System for the Production of Recombinant Antibody Fragments” in Methods Mol Biol.2021
- Author(s)
  *Nomura N, Nomura Y, Sato Y and *Iwata S.
- Total Pages
  340
- Publisher
  Humana Press
- ISBN
  9781071611258
- Data Source
  KAKENHI-PROJECT-19H00923
[Book] Methods in Enzymology, Vol. 629, "Tumor Immunology and Immunotherapy; Molecular Methods" (Edited by Lorenzo Galluzzi, Nils-Petter Rudqvist)2019
- Author(s)
  Norimichi Nomura, Yayoi Nomura, Yumi Sato, So Iwata
- Total Pages
  511
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-18K05334
[Book] Methods in Enzymology, Vol. 629, "Tumor Immunology and Immunotherapy; Molecular Methods" (Edited by Lorenzo Galluzzi, Nils-Petter Rudqvist)2019
- Author(s)
  Norimichi Nomura, Yayoi Nomura, Yumi Sato, So Iwata
- Total Pages
  511
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-19H00923
[Book] Methods Molecular Biology, Vol. 1700, Yamaguchi, A. and Nishino, K. (Eds.) “Bacterial Multidrug Exporters”2018
- Author(s)
  Jaenecke F., Nakada-Nakura, Y., Nagarathinam, K., Ogasawara, S., Liu, K., Hotta, Y., Iwata, S., Nomura, N., Tanabe, M
- Total Pages
  355
- Publisher
  Springer
- ISBN
  9781493974528
- Data Source
  KAKENHI-PROJECT-18K05334
[Book] Bacterial Multidrug Exporters2017
- Author(s)
  Jaenecke F., Nakada-Nakura, Y., Nagarathinam, K., Ogasawara, S., Liu, K., Hotta, Y., Iwata, S., Nomura, N., Tanabe, M
- Total Pages
  355
- Publisher
  Humana Press
- ISBN
  9781493974528
- Data Source
  KAKENHI-PROJECT-15K06968
[Book] 糖尿病学2016（第4章「GLUT5の立体構造とフルクトース輸送機構」）2016
- Author(s)
  野村紀通、岩田想
- Total Pages
  161
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-15K06968
[Journal Article] Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein2021
- Author(s)
  Nojima S, Fujita Y, Kimura KT, Nomura N, Suno R, Morimoto K, Yamamoto M, Noda T, Iwata S, Shigematsu H, Kobayashi T.
- Journal Title
  
  Structure
  
  Volume: 29 Pages: 252-260
- DOI
  10.1016/j.str.2020.11.007
- Peer Reviewed
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-19H03428, KAKENHI-PROJECT-19J12880, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K06172
[Journal Article] The structure of MgtE in the absence of magnesium provides new insights into channel gating2021
- Author(s)
  Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M.
- Journal Title
  
  PLoS Biol.
  
  Volume: 19
- DOI
  10.1371/journal.pbio.3001231
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334
[Journal Article] The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone2020
- Author(s)
  Asada Hidetsugu、Inoue Asuka、Ngako Kadji Francois Marie、Hirata Kunio、Shiimura Yuki、Im Dohyun、Shimamura Tatsuro、Nomura Norimichi、Iwanari Hiroko、Hamakubo Takao、Kusano-Arai Osamu、Hisano Hiromi、Uemura Tomoko、Suno Chiyo、Aoki Junken、Iwata So
- Journal Title
  
  Structure
  
  Volume: 28
- DOI
  10.1016/j.str.2019.12.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K16217, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-17K08264, KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-20K21392, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-18H02388
[Journal Article] Isolation and thermal stabilization of mouse ferroportin2020
- Author(s)
  Deshpande Chandrika N.、Azucenas Corbin R.、Qiao Bo、Nomura Norimichi、Xin Vicky、Font Josep、Iwata So、Ganz Tomas、Nemeth Elizabeta、Mackenzie Bryan、Jormakka Mika
- Journal Title
  
  FEBS Open Bio
  
  Volume: 11 Pages: 26-34
- DOI
  10.1002/2211-5463.13039
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334
[Journal Article] Structural insights into tetraspanin CD9 function2020
- Author(s)
  Umeda Rie、Satouh Yuhkoh、Takemoto Mizuki、Nakada-Nakura Yoshiko、Liu Kehong、Yokoyama Takeshi、Shirouzu Mikako、Iwata So、Nomura Norimichi、Sato Ken、Ikawa Masahito、Nishizawa Tomohiro、Nureki Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 11 Pages: 1606-1606
- DOI
  10.1038/s41467-020-15459-7
- NAID
  120006957458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06686, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334
[Journal Article] Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone2020
- Author(s)
  Im Dohyun、Inoue Asuka、Fujiwara Takaaki、Nakane Takanori、Yamanaka Yasuaki、Uemura Tomoko、Mori Chihiro、Shiimura Yuki、Kimura Kanako Terakado、Asada Hidetsugu、Nomura Norimichi、Tanaka Tomoyuki、Yamashita Ayumi、Nango Eriko、Tono Kensuke、Kadji Francois Marie Ngako、Aoki Junken、Iwata So、Shimamura Tatsuro
- Journal Title
  
  Nature Communications
  
  Volume: 11 Pages: 1-11
- DOI
  10.1038/s41467-020-20221-0
- NAID
  120006943309
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21392, KAKENHI-PLANNED-19H05781, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18H02394, KAKENHI-PROJECT-18K05334
[Journal Article] Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion2020
- Author(s)
  Matoba Kazuaki、Kotani Tetsuya、Tsutsumi Akihisa、Tsuji Takuma、Mori Takaharu、Noshiro Daisuke、Sugita Yuji、Nomura Norimichi、Iwata So、Ohsumi Yoshinori、Fujimoto Toyoshi、Nakatogawa Hitoshi、Kikkawa Masahide、Noda Nobuo N.
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 27 Pages: 1185-1193
- DOI
  10.1038/s41594-020-00518-w
- NAID
  40022756188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06532, KAKENHI-PROJECT-19K07265, KAKENHI-PROJECT-19K16071, KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05707, KAKENHI-PUBLICLY-20H05339, KAKENHI-PROJECT-16H06375, KAKENHI-PROJECT-19H05645, KAKENHI-PROJECT-18H03989, KAKENHI-PROJECT-18H04023, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K06097
[Journal Article] Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine2019
- Author(s)
  Kimura Kanako Terakado、Asada Hidetsugu、Inoue Asuka、Kadji Francois Marie Ngako、Im Dohyun、Mori Chihiro、Arakawa Takatoshi、Hirata Kunio、Nomura Yayoi、Nomura Norimichi、Aoki Junken、Iwata So、Shimamura Tatsuro
- Journal Title
  
  Nature Structural and Molecular Biology
  
  Volume: 26 Pages: 121-128
- DOI
  10.1038/s41594-018-0180-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08264, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-18H02388, KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05777
[Journal Article] FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics2019
- Author(s)
  Kinjo T., Terai K., Horita S., Nomura N., Sumiyama K., Togashi K., Iwata S., Matsuda M.
- Journal Title
  
  Nature Methods
  
  Volume: 16 Pages: 1029-1036
- DOI
  10.1038/s41592-019-0541-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K07066, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18H02490, KAKENHI-PROJECT-17J07950, KAKENHI-PROJECT-16H06280, KAKENHI-PLANNED-19H05777
[Journal Article] Structural basis for tumor necrosis factor blockade with the therapeutic antibody golimumab2018
- Author(s)
  Ono Masatsugu、Horita Shoichiro、Sato Yumi、Nomura Yayoi、Iwata So、Nomura Norimichi
- Journal Title
  
  Protein Science
  
  Volume: 印刷中 Pages: 1038-1046
- DOI
  10.1002/pro.3407
- NAID
  120006471155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06968, KAKENHI-PROJECT-18K05334
[Journal Article] Outward open conformation of a major facilitator superfamily multidrug/H+ antiporter provides insights into switching mechanism.2018
- Author(s)
  Nagarathinam K, Nakada-Nakura Y, Parthier C, Terada T, Juge N, Jaenecke F, Liu K, Hotta Y, Miyaji T, Omote H, Iwata S, Nomura N, Stubbs M, Tanabe M
- Journal Title
  
  Nat Commun
  
  Volume: 9 Pages: 4005-4005
- DOI
  10.1038/s41467-018-06306-x
- NAID
  120006528362
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K06114, KAKENHI-PROJECT-17K19489, KAKENHI-PROJECT-18H03179
[Journal Article] Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog2018
- Author(s)
  Asada H, Horita S, Hirata K, Shiroishi M, Shiimura Y, Iwanari H, Hamakubo T, Shimamura T, Nomura N, Kusano-Arai O, Uemura T, Suno C, Kobayashi T, Iwata S.
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 25 Pages: 570-576
- DOI
  10.1038/s41594-018-0079-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-18H02388
[Journal Article] The multidrug-resistance transporter MdfA from Escherichia coli: crystallization and X-ray diffraction analysis2017
- Author(s)
  Nagarathinam Kumar、Jaenecke Frank、Nakada-Nakura Yoshiko、Hotta Yunhon、Liu Kehong、Iwata So、Stubbs Milton T.、Nomura Norimichi、Tanabe Mikio
- Journal Title
  
  Acta Crystallographica Section F Structural Biology Communications
  
  Volume: 73 Pages: 423-430
- DOI
  10.1107/s2053230x17008500
- NAID
  120006318883
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06968
[Journal Article] High-resolution crystal structure of the therapeutic antibody pembrolizumab bound to the human PD-12016
- Author(s)
  Horita S, Nomura Y, Sato Y, Shimamura T, Iwata S, Nomura N.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 35297-35297
- DOI
  10.1038/srep35297
- NAID
  120005850219
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15J04343, KAKENHI-PROJECT-15K06968
[Journal Article] Structure and Molecular Mechanism of the Mammalian Fructose Transporter GLUT52016
- Author(s)
  野村紀通，岩田想
- Journal Title
  
  Journal of the Crystallographic Society of Japan
  
  Volume: 58 Issue: 3 Pages: 133-138
- DOI
  10.5940/jcrsj.58.133
- NAID
  130005159764
- ISSN
  0369-4585, 1884-5576
- Language
  Japanese
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06968
[Journal Article] A three-dimensional movie of structural changes in bacteriorhodopsin.2016
- Author(s)
  Nango, E., Royant, A.†, Kubo, M.† et al. (†equal contribution)(45名中2番目)
- Journal Title
  
  Nature
  
  Volume: 354 Pages: 1552-1557
- DOI
  10.1126/science.aah3497
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01055, KAKENHI-PROJECT-15H03841, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15H05476, KAKENHI-PROJECT-15K18486, KAKENHI-PROJECT-15K18523, KAKENHI-PROJECT-16H06315
[Journal Article] The intervening removable affinity tag (iRAT) production system facilitates Fv antibody fragment-mediated crystallography2016
- Author(s)
  Nomura Y, Sato Y, Suno R, Horita S, Iwata S, Nomura N.
- Journal Title
  
  Protein Science
  
  Volume: 25 Pages: 2268-2276
- DOI
  10.1002/pro.3035
- NAID
  120005841403
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15J04343, KAKENHI-PROJECT-15K06968, KAKENHI-PROJECT-15K08268
[Journal Article] Structure and transport mechanism of the mammalian fructose transporter GLUT5.2015
- Author(s)
  Nomura N, Verdon G, Kang HJ, Shimamura T, Nomura Y, Sonoda Y, Hussien SA, Qureshi AA, Coincon M, Sato Y, Abe H, Nakada-Nakura Y, Hino T, Arakawa T, Kusano-Arai O, Iwanari H, Murata T, Kobayashi T, Hamakubo T, Kasahara M, Iwata S, Drew D
- Journal Title
  
  Nature.
  
  Volume: 526 Pages: 397-401
- DOI
  10.1038/nature14909
- NAID
  120005657713
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06968, KAKENHI-PLANNED-24108007, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-25711004
[Journal Article] Platform for the rapid construction and evaluation of GPCRs for crystallography in Saccharomyces cerevisiae2012
- Author(s)
  Shiroishi M., et al.
- Journal Title
  
  Microb. Cell Fact.
  
  Volume: 11 Pages: 1-12
- DOI
  10.1186/1475-2859-11-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40150, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-23370049, KAKENHI-PROJECT-23657074, KAKENHI-PROJECT-23770123, KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-24659132, KAKENHI-PUBLICLY-24121715
[Journal Article] G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody2012
- Author(s)
  Hino T., et al
- Journal Title
  
  Nature.
  
  Volume: 482 Pages: 237-240
- DOI
  10.1038/nature10750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40150, KAKENHI-PROJECT-20221010, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22659059, KAKENHI-PROJECT-23370049, KAKENHI-PROJECT-23657074
[Journal Article] Evaluation of the Pichia pastorisexpression system for the production of GPCRs for structural analysis.2011
- Author(s)
  Asada, H., Uemura, T., Yurugi-Kobayashi, T., Shiroishi, M., Shimamura, T., Tsujimoto, H., Ito, K., Sugawara, T., Nakane, T., Nomura, N., Murata, T., Haga, T., Iwata, S., Kobayashi, T
- Journal Title
  
  Microbe Cell Fact
  
  Volume: 10 Pages: 24-24
- DOI
  10.1186/1475-2859-10-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04341, KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270
[Journal Article] Cloning, expression and purification of the anion exchanger 1 homologue from the basidiomvcete2011
- Author(s)
  Tokuda N, Igarashi K, Shimamura T(co-1st author), Yurugi-Kobayashi T, Shiroishi M, Ito K, Sugawara T, Asada H, Murata T, Nomura N, Iwata S, Kobayashi T.
- Journal Title
  
  Protein Expr Purif.
  
  Volume: 79(1) Pages: 81-7
- DOI
  10.1016/j.pep.2011.04.006
- NAID
  120003255719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-23657074
[Journal Article] Evaluation of the Pichiapastoris expression system for theproduction of GPCRs for structuralanalysis2011
- Author(s)
  Asada, H., Uemura, T., Yurugi-Kobayashi, T., Shiroishi, M., Shimamura, T., Tsujimoto, H., Ito, K., Sugawara, T., Nakane, T., Nomura, N., Murata, T., Haga, T. Iwata, S. and Kobayashi, T.
- Journal Title
  
  Microb. Cell Fact
  
  Volume: 10 Pages: 24-24
- URL
  http://www.microbialcellfactories.com/content/10/1/24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659059
[Journal Article] Cloning, expressionand purification of the anion exchanger 1homologue from basidiomycetePhanerochaete chrysosporium2011
- Author(s)
  Tokuda, N., Igarashi, K., Shimamura, T., Yurugi-Kobayashi, T., Shiroishi, M., Ito, K., Sugawara, T., Asada, H., Murata, T., Nomura, N., Iwata, S. and Kobayashi, T.
- Journal Title
  
  Protein Expr. Purif
  
  Volume: 79 Pages: 81-87
- URL
  http://www.sciencedirect.com/science/article/pii/S1046592811000866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659059
[Journal Article] Structure of a hyperthermophilic archaeal homing endonuclease, I-Tsp 0611 : Contribution of cross-domain polar networks to thermostability2007
- Author(s)
  Nakayama, H., T., Shimamura, T., Imagawa, N., Shirai, T., Itoh, Y., Sako, M., Miyano, H., Sakuraba, T., Oshima, N., Nomura, H., Tanga
- Journal Title
  
  J. Mol. Biol 365
  
  Pages: 362-378
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208020
[Journal Article] I-Apel : a novel intron-encoded LAGLIDADG homing endonuclease from the archaea, Aeropyrum @ernix K1.2005
- Author(s)
  Nomura N. et al.
- Journal Title
  
  Nucleic Acid Res. 33
- Data Source
  KAKENHI-PROJECT-16208020
[Patent] 膜蛋白質の立体構造を認識するモノクローナル抗体のスクリーニング方法2010
- Inventor(s)
  日野智也, 村田武士, 荒川孝俊, 野村紀通, 小林拓也, 岩田想
- Industrial Property Rights Holder
  日野智也, 村田武士, 荒川孝俊, 野村紀通, 小林拓也, 岩田想
- Filing Date
  2010-04-28
- Overseas
- Data Source
  KAKENHI-PROJECT-22570114
[Patent] 膜蛋白質の立体構造を認識するモノクローナル抗体のスクリーニング方法2010
- Inventor(s)
  岩田想・小林拓也・野村紀通
- Industrial Property Rights Holder
  科学技術振興機構
- Filing Date
  2010
- Overseas
- Data Source
  KAKENHI-PROJECT-22659059
[Presentation] 次世代構造創薬研究を先導するヒト膜タンパク質・抗体の生産技術支援2019
- Author(s)
  岩田　想、野村紀通
- Organizer
  BINDS公開シンポジウム2019
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] 次世代構造創薬研究を先導するヒト膜タンパク質・抗体の生産技術支援2019
- Author(s)
  岩田想，野村紀通
- Organizer
  BINDS公開シンポジウム2019
- Data Source
  KAKENHI-PROJECT-19H00923
[Presentation] 膜蛋白質のX線結晶構造解析を支援する抗体工学技術の確立2011
- Author(s)
  野村紀通, ら
- Organizer
  第84回日本生化学会大会シンポジウム「多様な生物種における膜タンパク質の機能理解を目指した新戦略」
- Place of Presentation
  京都国際会館
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22570114
[Presentation] 膜蛋白質のX線結晶構造解析を支援する抗体工学技術の確立2011
- Author(s)
  野村紀通,他
- Organizer
  第84回日本生化学会大会シンポジウム「多様な生物種における膜タンパク質の機能理解を目指した新戦略」
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22570114
[Presentation] 抗体フラグメントを用いたヒト膜タンパク質の結晶構造解析2010
- Author(s)
  岩田想, 野村紀通
- Organizer
  BioJapan2014アカデミックシーズ発表会
- Place of Presentation
  パシフィコ横浜(横浜市西区)
- Year and Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-22570114
[Presentation] 好気性超好熱菌Aeropyrum pernixTB5株由来ヒドロゲナーゼの精製と性状解析2007
- Author(s)
  西村宏・岩田恵里・野村良子・左子芳彦
- Organizer
  日本水産学会
- Place of Presentation
  東京海洋大学
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16208020
[Presentation] 好気性超好熱菌Aeropyrum pernix TB5株由来ヒドロゲナーゼの精製と性状解析2007
- Author(s)
  西村宏・岩田恵里・野村良子・左子芳彦
- Organizer
  日本水産学会
- Place of Presentation
  東京海洋大学
- Year and Date
  2007-03-28
- Data Source
  KAKENHI-PROJECT-16208020
[Presentation] Purification and characterization of hydrogenase from aerobic hyperther- mophilic archaeon Aaropyrum pernix TB52007
- Author(s)
  Nishimura, H., E., Iwata, Y., Nomura, Y., Sako
- Organizer
  The Japanese Society of Fisheries Scince
- Place of Presentation
  Tokyo Univ. of Marine Science and Technology, Tokyo
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208020

1. IWATA So (60452330)

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2. SAKO Yoshihiko (60153970)

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27. SHIROISHI Mitsunori

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Nomura Norimichi 野村 紀通

NOMURA Norimichi 野村 紀通

NOMURA Norimiti 野村 紀通

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Creation and crystallographic studies of artificial medium-sized aptamers that modulate membrane protein functionsPrincipal Investigator

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Crystallographic study of the mammalian bile acid transporter NTCP in complex with its conformation-specific antibodiesPrincipal Investigator

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Technologicaldevelopment for construction of synthetic proteins that facilitate membrane protein crystallizationPrincipal Investigator

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古細菌ゲノムに散在する可動性イントロンの集団内伝播と進化のダイナミクスPrincipal Investigator

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ゲノム工学技術への応用をめざした人工レアカッター酵素の開発と分子設計原理の解明Principal Investigator

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Nomura Norimichi 野村紀通

NOMURA Norimichi 野村紀通

NOMURA Norimiti 野村紀通