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Mitsuhashi Akira  三橋 暁

ORCIDConnect your ORCID iD *help
… Alternative Names

MITSUHASHI Akira  三橋 暁

三橋 暁  ミツハシ アキラ

三橋 曉  ミツハシ アキラ

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Researcher Number 40302541
Other IDs
External Links
Affiliation (Current) 2025: 獨協医科大学, 医学部, 教授
2025: 千葉大学, 大学院医学研究院, 特任教授
Affiliation (based on the past Project Information) *help 2020 – 2021: 千葉大学, 大学院医学研究院, 特任教授
2019: 千葉大学, 大学院医学研究院, 准教授
2016 – 2017: 千葉大学, 大学院医学研究院, 准教授
2012 – 2015: 千葉大学, 医学(系)研究科(研究院), 准教授
2012: 千葉大学, 医学研究科(研究院), 准教授 … More
2009 – 2011: Chiba University, 大学院・医学研究院, 准教授
2007 – 2008: Chiba University, Department of Reproductive Medicine, Lecture
2007: 千葉大学, 大学院・医学系研究科, 講師
2006: 千葉大学, 大学院医学研究院, 講師
2004: 千葉大学, 大学院・医学研究院, 助手
2003: 千葉大学, 医学部附属病院, 助手
2000 – 2001: 千葉大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology / Obstetrics and gynecology
Keywords
Principal Investigator
メトホルミン / 子宮体癌 / インスリン抵抗性 / 肥満 / 子宮内膜癌 / 子宮頸部癌 / 酸化的リン酸化阻害剤 / 糖代謝 / sgRNAスクリーニング / 癌代謝 … More / メチル化 / 婦人科腫瘍学 / ホモ欠失 / 3p21.3 / 子宮頸癌 / LOH / 3p21.3ホモ欠失 / HPV negative / cervical cancer / EGFR / HPV … More
Except Principal Investigator
ovulation induction / endometriosis / uterine leiomyoma / inhibitor / aromatase / 脂肪 / 妊孕性 / 排卵障害 / 催奇形性 / 排卵誘発 / 子宮内膜症 / 子宮筋腫 / 活性阻害剤 / アロマターゼ / GAMMA-CATENIN / BETA-CATENIN / GRNE EXPRESSION / CULTURED CELL / GENE AMPLIFICATION / CHROMOSOME 3 / OVARIAN CANCER / γ-catenin / β-catenin / 遺伝子発現 / 培養細胞 / 遺伝子増幅 / 第三染色体 / 卵巣癌 / 動物実験モデル / NOGマウス / 腎被膜下移植 / エストロゲン / 子宮内膜癌 Less
  • Research Projects

    (10 results)
  • Research Products

    (71 results)
  • Co-Researchers

    (18 People)
  •  Elucidation of abnormal metabolic profile of endometrial cancerPrincipal Investigator

    • Principal Investigator
      Mitsuhashi Akira
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Chiba University
  •  Clinical study of endometrial cancer prevention by metformin: targeting obesity and insulin resistancePrincipal Investigator

    • Principal Investigator
      Mitsuhashi Akira
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba University
  •  Chemoprevention of endometrial cancer by metfomrinPrincipal Investigator

    • Principal Investigator
      MITSUHASHI Akira
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba University
  •  Construction of xenograft models of human endometrial cancer in NOD/SCID IL-2R gamma null mice

    • Principal Investigator
      KATO Kazuyoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      公益財団法人がん研究会
      Chiba University
  •  To investigate of anti-neoplastic effect of metformin in endometrial cancerPrincipal Investigator

    • Principal Investigator
      MITSUHASHI Akira
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba University
  •  Study of PAX2 promoter methylation status in the carcinogenesis of estrogen dependent endometrial cancerPrincipal Investigator

    • Principal Investigator
      MITSUHASHI Akira
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba University
  •  Basic and Clinical study on endocrine therapy of gynecologic diseases targeting aromatase

    • Principal Investigator
      SHOZU Makio
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba University
      Kanazawa University
  •  子宮頸部癌における3p21.3領域のホモ欠失の検索Principal Investigator

    • Principal Investigator
      三橋 暁
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba University
  •  HPV陰性子宮頸部癌の発癌機構の解明Principal Investigator

    • Principal Investigator
      三橋 暁 (三橋 曉)
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba University
  •  MOLECULAR MECHANISM INVOLVED IN ONCOGENESIS AND PROGRESSION OF OVARIAN CANCER

    • Principal Investigator
      TANAKA Naotake
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      CHIBA UNIVERSITY

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2007 2006 Other

All Journal Article Presentation Other

  • [Journal Article] Lymphadenectomy issues in endometrial cancer.2021

    • Author(s)
      Konno Y, Asano H, Shikama A, Aoki D, Tanikawa M, Oki A, Horie K, Mitsuhashi A, Kikuchi A, Tokunaga H, Terao Y, Satoh T, Ushijima K, Ishikawa M, Yaegashi N, Watari H.
    • Journal Title

      J Gynecol Oncol

      Volume: 32 Issue: 2

    • DOI

      10.3802/jgo.2021.32.e25

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09796
  • [Journal Article] High prevalence of pulmonary embolism prior to cancer therapies in patients with ovarian and endometrial cancers detected by contrast‐enhanced CT using D‐dimer as an index2021

    • Author(s)
      Habu Yuji、Mitsuhashi Akira、Hanawa Shinsuke、Usui Hirokazu、Horikoshi Takuro、Uno Takashi、Shozu Makio
    • Journal Title

      Journal of Surgical Oncology

      Volume: 124 Issue: 1 Pages: 106-114

    • DOI

      10.1002/jso.26471

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09796
  • [Journal Article] Time-lapse monitoring of fertilized human oocytes focused on the incidence of 0PN embryos in conventional in vitro fertilization cycles. Kobayashi T, Ishikawa H, Ishii K, Sato A, Nakamura N, Saito Y, Hasegawa H, Fujita M, Mitsuhashi A, Shozu M.2021

    • Author(s)
      Kobayashi T, Ishikawa H, Ishii K, Sato A, Nakamura N, Saito Y, Hasegawa H, Fujita M, Mitsuhashi A, Shozu M.
    • Journal Title

      Sci Rep.

      Volume: 11 Issue: 1 Pages: 18862-18862

    • DOI

      10.1038/s41598-021-98312-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09748, KAKENHI-PROJECT-19K09796, KAKENHI-PROJECT-19K18663
  • [Journal Article] Medroxyprogesterone acetate plus metformin for fertility-sparing treatment of atypical endometrial hyperplasia and endometrial carcinoma: trial protocol for a prospective, randomised, open, blinded-endpoint design, dose-response trial (FELICIA trial)2020

    • Author(s)
      Mitsuhashi Akira、Kawasaki Yohei、Hori Makoto、Fujiwara Tadami、Hanaoka Hideki、Shozu Makio
    • Journal Title

      BMJ Open

      Volume: 10 Issue: 2 Pages: e035416-e035416

    • DOI

      10.1136/bmjopen-2019-035416

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09796
  • [Journal Article] New therapeutic approaches for the fertility-sparing treatment of endometrial cancer2020

    • Author(s)
      Mitsuhashi Akira、Shozu Makio
    • Journal Title

      Journal of Obstetrics and Gynaecology Research

      Volume: 46 Issue: 2 Pages: 215-222

    • DOI

      10.1111/jog.14155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09796
  • [Journal Article] Development of localized cul-de-sac endometrioid carcinoma associated with deep infiltrating endometriosis during remission of early endometrial cancer2020

    • Author(s)
      Seki Kumiko、Ishikawa Hiroshi、Hashimoto Rei、Mitsuhashi Akira、Ikeda Jun-ichiro、Shozu Makio
    • Journal Title

      Gynecologic Oncology Reports

      Volume: 31 Pages: 100526-100526

    • DOI

      10.1016/j.gore.2019.100526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09796
  • [Journal Article] Propensity score-matched analysis of systemic chemotherapy versus salvage hysterectomy for persistent cervical cancer after definitive radiotherapy/concurrent chemoradiotherapy.2020

    • Author(s)
      Takekuma M, Takahashi F, Mabuchi S, Kudaka W, Horie K, Ikeda M, Shikama A, Mitsuhashi A, Nagao S, Suzuki S, Mizuno M, Nishio S, Tokunaga H, Ota Y, Kasamatsu T, Kitagawa R, Toita T, Kobayashi H, Ishikawa M, Yaegashi N.
    • Journal Title

      BMC Cancer

      Volume: 20 Issue: 1 Pages: 1169-1169

    • DOI

      10.1186/s12885-020-07672-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08179, KAKENHI-PROJECT-19K09796
  • [Journal Article] Long-term outcomes of progestin plus metformin as a fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer patients2019

    • Author(s)
      Mitsuhashi Akira、Habu Yuji、Kobayashi Tatsuya、Kawarai Yoshimasa、Ishikawa Hiroshi、Usui Hirokazu、Shozu Makio
    • Journal Title

      Journal of Gynecologic Oncology

      Volume: 30 Issue: 6 Pages: 1-11

    • DOI

      10.3802/jgo.2019.30.e90

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09281, KAKENHI-PROJECT-19K09796
  • [Journal Article] Antitumor effects of metformin via indirect inhibition of protein phosphatase 2A in patients with endometrial cancer.2018

    • Author(s)
      Hanawa S, Mitsuhashi A, Shozu M.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 2 Pages: e0192759-e0192759

    • DOI

      10.1371/journal.pone.0192759

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Journal Article] Metformin alters DNA methylation genome-wide via the H19/SAHH axis.2017

    • Author(s)
      Zhong T, Men Y, Lu L, Geng T, Zhou J, Mitsuhashi A, Shozu M, Maihle NJ, Carmichael GG, Taylor HS, Huang Y.
    • Journal Title

      Oncogene

      Volume: 36 Issue: 17 Pages: 2345-2354

    • DOI

      10.1038/onc.2016.391

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Journal Article] Prospective evaluation of abnormal glucose metabolism and insulin resistance in patients with atypical endometrial hyperplasia and endometrial cancer.2017

    • Author(s)
      Mitsuhashi A, Uehara T, Hanawa S, Shozu M.
    • Journal Title

      Support Care Cancer.

      Volume: 25 Issue: 5 Pages: 1495-1501

    • DOI

      10.1007/s00520-016-3554-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Journal Article] Phase II study of medroxyprogesterone acetate plus metformin as a fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer2016

    • Author(s)
      Mitsuhashi A
    • Journal Title

      Ann Oncol

      Volume: 27 Issue: 2 Pages: 262-266

    • DOI

      10.1093/annonc/mdv539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Journal Article] Metformin potentiates the anticancer effects of cisplatin under normoxic conditions in vitro2015

    • Author(s)
      TAKASHI UEHARA, AKIRA MITSUHASHI, NOBUHIDE TSURUOKA, MAKIO SHOZU1
    • Journal Title

      ONCOLOGY REPORTS

      Volume: 33 Issue: 2 Pages: 744-750

    • DOI

      10.3892/or.2014.3611

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592504, KAKENHI-PROJECT-25670694
  • [Journal Article] 糖尿病治療薬メトホルミンが子宮体がんに奏効する可能性2015

    • Author(s)
      三橋暁
    • Journal Title

      産科と婦人科

      Volume: 82

    • Data Source
      KAKENHI-PROJECT-24592504
  • [Journal Article] 特集/婦人科悪性腫瘍治療に対するドラッグリポジショニングの幕開け -既存薬に秘められた新たな可能性- 4.糖尿病治療薬メトホルミンが子宮体がんに奏効する可能性2015

    • Author(s)
      三橋 暁
    • Journal Title

      産科と婦人科

      Volume: 82 Pages: 1099-1105

    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Journal Article] Effects of metformin on endometrial cancer cell growth in vivo: a preoperative prospective trial2014

    • Author(s)
      Akira Mitsuhashi, Takako Kiyokawa, Yasunori Sato, Makio Shozu
    • Journal Title

      Cancer

      Volume: 120 Issue: 19 Pages: 2986-2995

    • DOI

      10.1002/cncr.28853

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592504, KAKENHI-PROJECT-25670694
  • [Journal Article] 子宮体がんでの妊孕性温存療法の新たな展開2013

    • Author(s)
      三橋 暁
    • Journal Title

      産婦人科の実際

      Volume: 62 Pages: 1207-1213

    • Data Source
      KAKENHI-PROJECT-24592504
  • [Journal Article] 子宮体がんの妊孕性温存療法2013

    • Author(s)
      三橋 暁
    • Journal Title

      臨床婦人科産科

      Volume: 67 Pages: 498-504

    • Data Source
      KAKENHI-PROJECT-24592504
  • [Journal Article] Daily Low-Dose Cisplatin-Based Concurrent Chemoradiotherapy in Patients With Uterine Cervical Cancer With Emphasis on Elderly Patients: A Phase 2 Trial2012

    • Author(s)
      Mitsuhashi A, Uno T, Usui H, Nishikimi K, Yamamoto N, Watanabe M, Tate S, Hirashiki K, Kato K, Yamazawa K, Shozu M
    • Journal Title

      Int J Gynecol Cancer

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591847
  • [Journal Article] The application of a newly developed linear stapler preloaded with the tissue reinforcement to distal pancreatectomy in the management of ovarian cancer2011

    • Author(s)
      Kazuyoshi Kato, Shinichi Tate, Takashi Uehara, Hirokazu Usui, Akira Mitsuhashi, Makio Shozu
    • Journal Title

      European Journal of Gynaecological Oncology

      Volume: 32 Pages: 579-581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591847
  • [Journal Article] The application of a newly developed linear stapler preloaded with the tissue reinforcement to distal pancreatectomy in the management of ovarian cancer2011

    • Author(s)
      Kazuyoshi Kato, Shinichi Tate, Takashi Uehara, Hirokazu Usui, Akira Mitsuhashi, Makio Shozu
    • Journal Title

      Eur J Gynaecol Oncol

      Volume: 32 Pages: 579-581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591847
  • [Journal Article] Postoperative concurrent daily low-dose cisplatin-based chemoradiation improves the prognosis of patients with pathologic T2b or N1 cervical cancer2010

    • Author(s)
      Mitsuhashi A, Uno T, Usui H, Tate S, Hirashiki K, Kato K, Kiyohara H, Kato S, Ito H, Shozu M
    • Journal Title

      Anticancer Res

      Volume: 30 Pages: 2341-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591847
  • [Journal Article] Primary synovial sarcoma in fallopian tube : case report and literature review.2007

    • Author(s)
      Mitsuhashi A, Nagai Y, Suzuka K, Yamazawa K, Nojima T, Nikaido T, Ishikura H, Matsui H, Shozu M.
    • Journal Title

      Int J Gynecol Pathol. 26・1

      Pages: 34-7

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209049
  • [Journal Article] Primary synovial sarcoma in fallopian tube: case report and literature review.2007

    • Author(s)
      Mitsuhashi A, Nagai Y, Suzuka K, Yamazawa K, Nojima T, Nikaido T, Ishikura H, Matsui H, Shozu M.
    • Journal Title

      Int J Gynecol Pathol. 26(1)

      Pages: 34-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209049
  • [Journal Article] 排卵誘発剤としてのアロマターゼ阻害剤2007

    • Author(s)
      生水真紀夫, 碓井宏和, 三橋暁, 松井英雄
    • Journal Title

      産科と婦人科 74・8

      Pages: 929-937

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209049
  • [Journal Article] An aromatase inhibitor as an ovulation induction drug.2007

    • Author(s)
      Shozu M, Usui H, Mitsuhashi A, Matsui H.
    • Journal Title

      Obstet gynecol. 74(8)

      Pages: 929-937

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209049
  • [Journal Article] 排卵誘発剤としてのアロマターゼ阻害剤2007

    • Author(s)
      生水 真紀夫, 碓井 宏和, 三橋 暁, 松井 英雄
    • Journal Title

      産科と婦人科 74

      Pages: 929-937

    • Data Source
      KAKENHI-PROJECT-16209049
  • [Journal Article] Primary synovial sarcoma in fallopian tube:case report and literature revlew.2007Jan;26(1):34-7.Review.2007

    • Author(s)
      Mitsuhashi A, Nagai Y, Suzuka K, Yamazawa K, Nojima T, Nikaido T, lshikura H, Matsui H, Shozu M.
    • Journal Title

      Int J Gynecol Pathol 26

      Pages: 34-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16209049
  • [Journal Article] 子宮内膜症のスクリーニング2006

    • Author(s)
      生水真紀夫, 山澤功二, 三橋暁, 確井宏和, 木原真紀
    • Journal Title

      産婦人科の実際 55(11)

      Pages: 1894-1897

    • Data Source
      KAKENHI-PROJECT-16209049
  • [Presentation] Metformin may attenuate the effect of hyperprolactinemia induced by medroxyprogesterone acetate during fertility-sparing treatment for patients with atypical endometrial hyperplasia and endometrial cancer2019

    • Author(s)
      Mitsuhashi A, Gu W, Habu Y, Kobayashi T, Shozu M.
    • Organizer
      ESGO 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09796
  • [Presentation] Antitumor effects of metformin via indirect inhibition of protein phosphatase PP2A in patients with endometrial cancer2016

    • Author(s)
      Shinsuke Hanawa, Akira Mitsuhashi, Makio Shozu
    • Organizer
      16th Biennial Meeting of the International Gynecologic Cancer Society (IGCS)
    • Place of Presentation
      Lisbon,Portugal
    • Year and Date
      2016-10-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Presentation] 子宮体癌に対する メトホルミン療法の応用2016

    • Author(s)
      三橋 暁
    • Organizer
      第16回関東ホルモンと癌研究会
    • Place of Presentation
      東京大学医科学研究所附属病院(東京都港区)
    • Year and Date
      2016-01-30
    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Presentation] メトホルミン投与はインスリン抵抗性を有する患者で子宮体癌組織のPP2A発現を抑制する2016

    • Author(s)
      塙伸輔、三橋暁、生水真紀夫
    • Organizer
      日本産科婦人科学会学術講演会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Presentation] 子宮体癌組織のPP2Aの発現はメトホルミン投与で抑制される2016

    • Author(s)
      塙伸輔、三橋暁、生水真紀夫
    • Organizer
      日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      米子コンベンションセンター(鳥取県米子市)
    • Year and Date
      2016-07-08
    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Presentation] 子宮体癌に対するメドロキシプロゲステロン+メトホルミン併用妊孕性温存療法の臨床第2相試験2016

    • Author(s)
      三橋暁、塙伸輔、碓井宏和、生水真紀夫
    • Organizer
      日本産科婦人科学会学術講演会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-15K10702
  • [Presentation] メトホルミンは間接的に子宮内膜癌患者の増殖を抑制する2013

    • Author(s)
      三橋 暁
    • Organizer
      第14回ホルモンと癌研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] メトホルミンは単独および抗がん薬との併用で子宮体癌細胞の増殖を抑制する2013

    • Author(s)
      植原 貴史、三橋 暁
    • Organizer
      第65回日本産科婦人科学会 学術講演会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] メトホルミンは間接的に子宮内膜癌患者の増殖を抑制する2013

    • Author(s)
      三橋 暁
    • Organizer
      第65回日本産科婦人科学会 学術講演会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] メトホルミンは間接的に子宮内膜癌患者の増殖を抑制する2013

    • Author(s)
      三橋 暁
    • Organizer
      第54回 日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] Metformin prevents recurrence of endometrial cancer or atypical endometrial hyperplasia after progestin therapy and improves insulin resistance for fertility-sparing treatment in young women.2012

    • Author(s)
      A Mitsuhashi et al.
    • Organizer
      15th ICHSHC
    • Place of Presentation
      Kanazawa, Japan
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] 低濃度メトフォルミンは、抗がん薬との併用で子宮体癌細胞に対し、相乗相加効果は示さない2012

    • Author(s)
      植原貴史, 三橋暁, 他
    • Organizer
      第12回関東ホルモンと癌研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-19
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮体癌・子宮内膜異型増殖症に対するメドロキシプロゲステロン+メトホルミン併用妊孕性温存療法の前方視的試験.2012

    • Author(s)
      三橋 暁
    • Organizer
      第52回日本婦人科腫瘍学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] Therapeutic doses of metformin suppresses cell proliferation of endometrial cancer in vivo.2012

    • Author(s)
      A Mitsuhashi et al.
    • Organizer
      14th IGCS
    • Place of Presentation
      Vancouver ,Canada
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] 子宮体癌に対するメドロキシプロゲステロン+メトホルミン併用妊孕性温存療法の前方視的試験2011

    • Author(s)
      三橋暁, 他
    • Organizer
      第50回婦人科腫瘍学会
    • Place of Presentation
      札幌
    • Year and Date
      2011-07-22
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] SURGICAL ANATOMY OF THE VAGINAL AND INFERIOR VESICAL ARTERIES IN NERVE-SPARING RADICAL HYSTERECTOMY2011

    • Author(s)
      Kazuyoshi Kato, K.Nishikimi, H.Usui, S.Tate, N.Yamamoto, K.Yamazawa, Akira Mitsuhashi, Makio Shozu
    • Organizer
      17th International Meeting Of The European Society Of Gynaecological Oncology
    • Place of Presentation
      Milan Convention Center(イタリア ミラノ)
    • Year and Date
      2011-09-12
    • Data Source
      KAKENHI-PROJECT-22591847
  • [Presentation] The effect of metformin on cell proliferation in patients with endometrial cancer2011

    • Author(s)
      Akira Mitsuhashi, et al
    • Organizer
      2011 ASCO Annual Meeting
    • Place of Presentation
      アメリカ・シカゴ
    • Year and Date
      2011-06-03
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 骨盤自律神経温存広汎子宮全摘術における下膀胱動脈の臨床解剖学的検討2011

    • Author(s)
      加藤一喜、錦見恭子、三橋暁、生水真紀夫, 他
    • Organizer
      第50回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2011-07-24
    • Data Source
      KAKENHI-PROJECT-22591847
  • [Presentation] 子宮体癌に対するメドロキシプロゲステロン+メトホルミン併用妊孕性温存療法の前方視的試験2011

    • Author(s)
      三橋暁, 他
    • Organizer
      第12回ホルモンと癌研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-15
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] The effect of metformin on cell proliferation in patients with endometrial cancer2011

    • Author(s)
      三橋暁
    • Organizer
      2011 ASCO Annual Meeting
    • Place of Presentation
      シカゴ(招待講演)
    • Year and Date
      2011-06-03
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮体癌に対するメドロキシプロゲステロン+メトホルミン併用妊孕性温存療法の前方視的試験2011

    • Author(s)
      三橋暁
    • Organizer
      第12回ホルモンと癌研究会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-07-15
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] Metformin prevents recurrence following discontinuation of progestin therapy for fertility-sparing treatment in young women with endometrial cancer or atypical endometrial hyperplasia2011

    • Author(s)
      三橋暁
    • Organizer
      The 17^<th> International Meeting of the European Society of Gynecological Oncology (ESGO)
    • Place of Presentation
      ミラノ(招待講演)
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] Metformin prevents recurrence following discontinuation of progestin therapy for fertility-sparing treatment in young women with endometrial cancer or atypical endometrial hyperplasia2011

    • Author(s)
      Akira Mitsuhashi, et al
    • Organizer
      The 17^<th> International Meeting of the European Society of Gynecological Oncology
    • Place of Presentation
      (ESGO)(イタリア・ミラノ)
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮体癌に対するメドロキシプロゲステロン+メトホルミン併用妊孕性温存療法の前方視的試験2011

    • Author(s)
      三橋暁, 他
    • Organizer
      第63回日本産科婦人科学会学術講演会
    • Place of Presentation
      大阪
    • Year and Date
      2011-08-29
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮体癌に対する内分泌療法2011

    • Author(s)
      三橋暁, 他
    • Organizer
      第11回関東ホルモンと癌研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-01-29
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮体癌に対するメドロキシプロゲステロン+メトホルミン併用妊孕性温存療法の前方視的試験2011

    • Author(s)
      三橋暁
    • Organizer
      第50回婦人科腫瘍学会
    • Place of Presentation
      札幌(招待講演)
    • Year and Date
      2011-07-22
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮体癌に対するメドロキシプロゲステロン+メトホルミン併用妊孕性温存療法の前方視的試験2011

    • Author(s)
      三橋暁
    • Organizer
      第63回日本産科婦人科学会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-08-30
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮内膜癌に対するメトホルミンの抗腫瘍効果とその機序の検討2010

    • Author(s)
      三橋暁
    • Organizer
      婦人科腫瘍学会
    • Place of Presentation
      筑波
    • Year and Date
      2010-07-22
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮内膜癌に対するメトホルミンの抗腫瘍効果とその機序の検討2010

    • Author(s)
      三橋暁, 他
    • Organizer
      第48回婦人科腫瘍学会
    • Place of Presentation
      札幌
    • Year and Date
      2010-07-22
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] Metformin directly inhibits cell proliferation in endometrial cancer2010

    • Author(s)
      Akira Mitsuhashi
    • Organizer
      14^<th> international congress of Hormonal Steroid and Hormones&Cancer
    • Place of Presentation
      エジンバラ
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮体癌に対するメトホルミンの効果:作用機序の検討と臨床応用2010

    • Author(s)
      三橋暁, 他
    • Organizer
      第11回ホルモンと癌研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] 子宮体癌に対するメトホルミンの効果:臨床応用と作用機序の検討2010

    • Author(s)
      三橋暁
    • Organizer
      第10回関東ホルモンと癌研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-01-23
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] Metformin directly inhibits cell proliferation in endometrial cancer2010

    • Author(s)
      Akira Mitsuhashi, et al
    • Organizer
      14^<th> international congress of Hormonal Steroid and Hormones & Cancer
    • Place of Presentation
      イギリス・エジンバラ
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21592123
  • [Presentation] The measurements of serum human chorionic gonado tropin (HCG) in patients with gestational trophoblastic neoplasia (GTN) using eith two different commercial Hgg kits.2007

    • Author(s)
      Hideo Matsui, Maki Kihara, Hirokazu Usui, Emiri Nakada, Shinnichi Tate, Akira Mitsuhashi, Makio Shozu
    • Organizer
      The 14^<th> World Congress on Gestational Trophoblastic Diseases.
    • Place of Presentation
      Fukuoka
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209049
  • [Presentation] Protease profile of conditioned medium from choriocarcinoma cell lines.2007

    • Author(s)
      H. Usui, H. Matsui, A Mitsuhashi, M Kihara, B batzoring, E. Nakada, M. shozu
    • Organizer
      The 14^<th> World Congress on Gestaional Trophoblastic Diseases
    • Place of Presentation
      Fukouka
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209049
  • [Presentation] Protease profile of conditioned medium from choriocarcinoma cell lines.2007

    • Author(s)
      H. Usui, H. Matsui, A. Mitsuhashi, M. Kihara, B. Batzorig, E. Nakada, M. Shozu
    • Organizer
      The 14^<th>World Congress on Gestational Trophoblastic Diseases
    • Place of Presentation
      Fukuoka
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209049
  • [Presentation] The measurements of serum human chorionic gonadotropin (hCG) in patients with gestational trophoblastic neoplasia (GTN) using eith two different commercial hCG kits.2007

    • Author(s)
      Hideo Matsui, Maki Kihara, Hirokazu Usui, Emiri Nakada, Shinnichi Tate, Akira Mitsuhashi, Makio Shozu.
    • Organizer
      The 14^<th>World Congress on Gestational Trophoblastic Diseases
    • Place of Presentation
      Fukuoka
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209049
  • [Presentation] A phase II study of medroxyprogesterone acetate plus metformin as fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer.

    • Author(s)
      Mitsuhashi, A. Usui, H. Satoh, Y. Kiyokawa, T. Shozu, M.
    • Organizer
      ASCO2014
    • Place of Presentation
      CHIKAGO(USA)
    • Year and Date
      2014-05-30 – 2014-06-03
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] Prospective evaluation of glucose tolerance and insulin resistance among patients with endometrial cancer and atypical endometrial hyperplasia

    • Author(s)
      Mitsuhashi, A. Hanawa, S. Yamamoto, N. Uehara, T. Nishikimi, K. Tate, S. Usui, H. Shozu, M.
    • Organizer
      ESMO2014
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2014-09-26 – 2014-09-30
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] メトホルミンはインスリン抵抗性改善による間接効果で子宮内膜癌の増殖を抑制する

    • Author(s)
      三橋 暁
    • Organizer
      第88回日本内分泌学会
    • Place of Presentation
      ホテルニューオータニ東京(東京都千代田区)
    • Year and Date
      2015-04-23 – 2015-04-25
    • Data Source
      KAKENHI-PROJECT-24592504
  • [Presentation] Prospective evaluation of abnormal glucose metabolism and insulin resistance among patients with endometrial cancer and atypical endometrial hyperplasia

    • Author(s)
      Akira Mitsuhashi, Shinsuke Hanawa, Noriko Yamamoto, Takashi Uehara, Kyoko Nishikimi, Shinichi Tate, Hirokazu Usui, Makio Shozu
    • Organizer
      第66回日本産科婦人科学会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2014-04-18 – 2014-04-20
    • Data Source
      KAKENHI-PROJECT-24592504
  • []

  • 1.  SHOZU Makio (30226302)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 30 results
  • 2.  USUI Hirokazu (90375634)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 3.  KATO Kazuyoshi (80399451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  ISHIKAWA Hiroshi (70553973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  NISHIKIMI Kyoko (00536302)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  YAMAMOTO Noriko (30586722)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  TANAKA Naotake (80236611)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SEKIYA Souei (00092065)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  INOUE Masaki (10127186)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KIHARA Maki (20375760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 11.  MURAKAMI Koichi (20242555)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  海野 洋一 (90375759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  小野 俊介 (40345591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  植原 貴史 (70568659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  羽生 裕二 (40816162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  安西 尚彦 (70276054)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KOBAYASHI Tatsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  TOITA Takahumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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