KUMADA Maki 熊田真樹

Researcher Number	40326830
External Links
Affiliation (based on the past Project Information) *help	2011: 自治医科大学, 医学部・医学科, 准教授 2009 – 2011: 自治医科大学, 医学部, 准教授 2006 – 2007: 自治医科大学, 医学部, 助教 2006: 自治医科大学, 医学部, 講師 2000 – 2005: Jichi Medical School, Dept. of Medicine, Assist. Professor, 医学部, 助手
Review Section/Research Field	Principal Investigator Legal medicine Except Principal Investigator Legal medicine / Legal medicine / Anesthesiology/Resuscitation studies / Medical sociology / Hematology
Keywords	Principal Investigator 血液型 / 分子遺伝学 / ノックアウトマウス Except Principal Investigator Rh variant / 遺伝子多型 / Rh式血液型 / 変異型 / Rh血液型 / Weak D / 自己免疫性溶血性貧血 … More / Rh式血液型システム / Rh変異型 / 組換え / 分子進化 / Rh blood group system / Nucleotide substitution / Recombination / Molecular evolution / ラットABH抗原 / トランスジェニックラット / ラットABHオーソログ / ラットABOオーソログ / mimotope / linear peptide / オピオイド / 術後鎮痛 / 術後悪心・嘔吐 / 癌 / 術後痛 / 遺伝子情報 / 生活習慣病 / 行動変容 / 健康教育 / 遺伝子頻度 / 地域差 / 高血圧 / 遺伝子 / SNP / 塩分摂取 / 遺伝子検査 / GNB3 / 生活習慣 / RH遺伝子 / RHAG遺伝子 / プロモーター / エンハンサー / 抗原エピトープ / 遺伝子解析 / Rh blood system / RH gene / RHAG gene / promoter / enhancer / epitope / variant / genetic analysis / partial D / 分子遺伝学 / RHD遺伝子 / RHCE遺伝子 / マウスゲノム / Rh30遺伝子 / マウスオーソログ / weak D / エピトープ / Rhmod / Rh blood group / Partial D / Molecular genetics / RHD gene / RHCE gene / Mouse genome / 塩基置換・gap / Rh genotyping法 / 一塩基多型 / マイクロサテライト多型 / Rhgenotyping法 / Gaps / Rh genotyping / microsatellite / single nucleotide polymorphisms / ABOオーソログ / rat ABO homologue / paralogous gene / ABH antigen expression / transgenic rat / 移植抗原 / ABO transgenic rat / transplantation / ABO evolution / rat ABO antigen / 塩基置換 / orthologous RH gene superfamily / 多型 / 染色体マッピング / orthologous RH gene superfami1y / RH superfamily / Orthologous RH gene superfamily / Polymorphisms / Chromosome mapping / 抗赤血球自己抗体 / ランダムペプチドライブラリー / バンド3 / 分子相同性 / ミモトープ / Coombs陰性自己免疫性溶血性貧血 / CD47 / 交叉反応 / autoimmune hemolytic anemia / Rh blood groups / autoantibody / random peptide library / band 3 / molecular mimicry / トランスジェニックマウス / 炎症 / 新生児死亡 / 肥満 / 糖尿病 / ゲノムバンク / 本態性高血圧 / 間質性肺炎 / genome bank / Hypertension / inflammation / retinol binding protein 4 / association stud / type2 diabetes Less

Exploratory study of a usability of gene information on the health promotion and prevention of disease in the community setting
- Principal Investigator
  
  OKAYAMA Masanobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical sociology
- Research Institution
  Jichi Medical University
オピオイド受容体関連遺伝子の遺伝子多型とオピオイドの鎮痛効果及び副作用との関連
- Principal Investigator
  
  井上荘一郎
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Jichi Medical University
Molecularr epidemiology about unexpected sudden death
- Principal Investigator
  
  IWAMOTO Sadahiko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  Jichi Medical University
Development of model animal to reveal the antibody production for ABO blood group antigens.
- Principal Investigator
  
  IWAMOTO Sadahiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Jichi Medical School
The analysis of Rh antigen (polypeptide) function and the molecular evolution of orthologous RH genes in various species.
- Principal Investigator
  
  OKUDA Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Jichi Medical School
The study on the mechanism of production of autoantibodies in autoimmune hemolytic anemia.
- Principal Investigator
  
  KAMESAKI Toyomi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Rh蛋白複合体関連遺伝子ノックアウトマウスの作成とその遺伝学・生物学的解析Principal Investigator
- Principal Investigator
  
  熊田真樹
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Legal medicine
- Research Institution
  Jichi Medical University
Further investigation on the Rh blood group system for the expression of the RH gene and the epitopes of the Rh antigens
- Principal Investigator
  
  KAJII Eiji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  Jichi Medical School
The molecular genetic analysis and its application of single nucleotide polymorphisms and microsatellite in both RH genes.
- Principal Investigator
  
  OKUDA Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Jichi Medical School
Establishment of transgenic rat expressing human A or B Transferase gene and cloning of rat paralogous genes equivalent of human histo-blood group ABO gene.
- Principal Investigator
  
  IWAMOTO Sadahiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Jichi Medical School
Molecular genetical analysis of the epitopes on Rh blood group antigen and establishment of genetic examination system in RH genes.
- Principal Investigator
  
  KAJII Eiji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Legal medicine
- Research Institution
  Jichi Medical School

All 2010 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI2010
- Author(s)
  熊田真樹, 他
- Journal Title
  
  Obesity 18
  
  Pages: 1006-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390168
[Journal Article] Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI2010
- Author(s)
  Munkhtulga L, Kumada M(8番目), et al(18名)
- Journal Title
  
  Obesity
  
  Volume: 18 Pages: 1006-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390168
[Journal Article] Identification of a regulatory SNP in the retinol binding protein 4 gene associated with type 2 diabetes in Mongolia.2007
- Author(s)
  Munkhtulga L, Nakayama K, Utsumi N, Yanagisawa Y, Gotoh T, Omi T, Kumada M, Erdenebulgan B, Zolzaya K, Lkhagvasuren T, Iwamoto S.
- Journal Title
  
  Hum Genet. 120
  
  Pages: 879-888
- Data Source
  KAKENHI-PROJECT-17390205
[Journal Article] An intronic variable number of tandem repeat polymotphisms of the cold-induced autoinflammatory syndrome 1(CIAS1) gene modifies gene expression and is associated with essential hypertension.2006
- Author(s)
  Omi T, Kumada M, Kamesaki T, Okuda H, Munkhtulga L, Yanagisawa Y, Utsumi N, Gotoh T, Hata A, Soma M, Umemura S, Ogihara T, Takahashi N, Tabara Y, Shimada K, Mano H, Kajii E, Miki T, Iwamoto S.
- Journal Title
  
  Eur J Hum Genet. 14
  
  Pages: 1295-305
- Data Source
  KAKENHI-PROJECT-17390205
[Journal Article] CATERPILLER遺伝子群のSNPタイピングによる本態性高血圧との関連解析2006
- Author(s)
  北村歌奈子, 近江俊徳, 熊田真樹, 後藤孝也, 宇津見七海, ウハグワスレンムンフトルガ, 坂本敦司, 岩本禎彦
- Journal Title
  
  DNA多型 14
  
  Pages: 264-266
- Data Source
  KAKENHI-PROJECT-17390205
[Journal Article] Genetic heterogeneity in a susceptible region for essential hypertension among demographically different local populations in Japan2005
- Author(s)
  Kumada M.
- Journal Title
  
  Community Genet 11
  
  Pages: 150-9
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390205
[Journal Article] Aly/REF, a factor for mRNA transport, activates RH gene promoter function.2005
- Author(s)
  Suganuma H, Kumada M, Omi T, Gotoh T, Lkhagvasuren M, Okuda H, Kamesaki T, Kajii E, Iwamoto S.
- Journal Title
  
  FEBS J. 272
  
  Pages: 2696-2704
- Data Source
  KAKENHI-PROJECT-17390205
[Journal Article] cDNA cloning, mapping and polymorphism of the porcine Rhesus(RH) gene.2004
- Author(s)
  Omi T, Kumada M, Kamesaki T, Okuda H, Kajii E, Iwamoto S, Vogeli P, Schelling C, Stranzinger G
- Journal Title
  
  DNA Polymorphism 12
  
  Pages: 12-15
- NAID
  10013660627
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591018
[Journal Article] ブタRhesus(RH)遺伝子のcDNAクローニング、マッピング、多型解析2004
- Author(s)
  近江俊徳, 熊田真樹, 亀崎豊実, 奥田浩, 梶井英治, 岩本禎彦
- Journal Title
  
  DNA多型 12
  
  Pages: 12-15
- Data Source
  KAKENHI-PROJECT-15591018
[Journal Article] cDNA cloning, mapping and polymorphism of the porcine Rhesus (RH) gene.2004
- Author(s)
  Omi T, Kumada M, Kamesaki T, Okuda H, Kajii E, Iwamoto S, Voegeli P, Stranzinger G, Neuenshwander S
- Journal Title
  
  DNA polymorphism 12
  
  Pages: 262-263
- NAID
  10013660627
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590587
[Journal Article] A novel mutation in the RHD gene in Japanese individuals with weak D, encoding an amino acid change in the 11th transmembranous domain of the RhD protein transmembranous portion of the RhD protein.2003
- Author(s)
  Kamesaki T, Kumada M, Omi T, Okuda H, Iwamoto S, Takahashi J, Kimura K, Hirayama F, Kamata H, Obara K, Taniguchi M, Tani Y, Kajii E.
- Journal Title
  
  Vox Sang. 84
  
  Pages: 141-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591018
[Journal Article] A novel mutation in the RHD gene in Japanese individuals with weak D, encoding an amino acid change in the 11th transmembranous domain of the RhD protein.2003
- Author(s)
  Kamesaki T, Kumada M, Omi T, Okuda H, Iwamoto S, Takahashi J, Kimura K, Hirayama F. Kamata H, Obara K, Taniguchi M, Tani Y, Kajii E.
- Journal Title
  
  Vox Sang 84
  
  Pages: 141-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590586
[Journal Article] Gene duplication and polymorphism of rat ABO homologue.2003
- Author(s)
  S.Iwamoto, M.Kumada.T.Kamesaki, H.Okuda, E.Kajii.
- Journal Title
  
  DNA polymorphism 11
  
  Pages: 38-41
- NAID
  10013995330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590586
[Journal Article] A novel mutation in the RHD gene in Japanese individuals with weak D, encoding an amino acid change in the 11th transmembranous domain of the RhD protein transmembranous portion of the RhD protein.2003
- Author(s)
  Kamesaki T, Kumada M, Omi T, Okuda H, Iwamoto S, Takahashi J, Kimura K, Hirayama F, Kamata H, Obara K, Taniguchi M, Tani Y, Kajii E
- Journal Title
  
  Vox Sang 84
  
  Pages: 141-141
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590587
[Journal Article] Gene duplication and polymorphism of rat ABO homologue.2003
- Author(s)
  Iwamoto S, Kumada M, Kamesaki T, Okuda H, Kajii E.
- Journal Title
  
  DNA Polymorphism 11
  
  Pages: 38-41
- NAID
  10013995330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591018
[Journal Article] DNA-based identification resolved suspected misdiagnosis due to contaminated cytological specimens.2003
- Author(s)
  Iwamoto S, Kamesaki T, Kumada M, Omi T, Okuda H, Hasegawa T, Sakural S, Kajii E
- Journal Title
  
  Legal Medicine 5
  
  Pages: 246-250
- NAID
  50000002091
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590587
[Journal Article] DNA-based identification resolved suspected misdiagnosis due to contaminated cytological specimens.2003
- Author(s)
  Iwamoto S, Kamesaki T, Kumada M, Omi T, Okuda H, Hasegawa T, Sakurai S, Kajii E.
- Journal Title
  
  Leg Med 5
  
  Pages: 246-250
- NAID
  50000002091
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590586
[Journal Article] DNA-based identification resolved suspected misdiagnosis due to contaminated cytological specimens.2003
- Author(s)
  Iwamoto S, Kamesaki T, Kumada M, Omi T, Okuda H, Hasegawa T, Sakurai S, Kajii E.
- Journal Title
  
  Leg Med 5
  
  Pages: 246-250
- NAID
  50000002091
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591018
[Journal Article] Gene duplication and polymorphism of rat ABO homologue.2003
- Author(s)
  Iwamoto S, Kumada M, Kamesaki T, Okuda H, Kajii E
- Journal Title
  
  DNA polymorphism 11
  
  Pages: 38-41
- NAID
  10013995330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590587
[Journal Article] Aly/REF, a factor for mRNA transport, activates RH gene promoter function
- Author(s)
  Hiroshi Suganuma, Maki Kumada, Toshinori Omi, Takaya Gotoh, Munkhtulga Lkhagvasuren, Hiroshi Okuda, Toyomi Kamesaki, Eiji Kajii, Sadahiko Iwamoto
- Journal Title
  
  FEBS J (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590586
[Journal Article] Identification and characterization of novel peroxisome proliferators activated receptor gamma(PPARγ) transcriptional variants in pig and human.
- Author(s)
  Omi T, Kumada M, Gotoh T, Kamesaki T, Okuda H, Kajii E, Iwamoto S.
- Journal Title
  
  DNA polymorphism (in press)
- NAID
  10015685709
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590586
[Presentation] Comparative study of polymorphisms on Genes associated with lifestyle related diseases in Asian and Pacific populations.2007
- Author(s)
  Nakayama K, Munkhtulga L, Yanagisawa Y, Utsumi N, Kumada M, Gotoh T, jwamoto S, Kagawa Y
- Organizer
  The 39th conference of Asia-Pacific academic consortium for public health.
- Place of Presentation
  坂戸
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-17390205
[Presentation] トルコ鞍部・下垂体出血によって受傷約2週間後に急変・死亡したと推定される1例2007
- Author(s)
  坂本敦司、小山田隆、岩本禎彦、熊田真樹、後藤孝也、村田一素、奥田浩、梶井英治
- Organizer
  第13回遺伝診療学会
- Place of Presentation
  松山
- Year and Date
  2007-07-28
- Data Source
  KAKENHI-PROJECT-17390205

1. KJII Eiji (40204391)

# of Collaborated Projects: 9 results

# of Collaborated Products: 12 results
2. KAMESAKI Toyomi (90316513)

# of Collaborated Projects: 8 results

# of Collaborated Products: 14 results
3. IWAMOTO Sadahiko (10232711)

# of Collaborated Projects: 8 results

# of Collaborated Products: 19 results
4. OKUDA Hiroshi (50285772)

# of Collaborated Projects: 7 results

# of Collaborated Products: 14 results
5. OMI Toshnori (40296091)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
6. OKAYAMA Masanobu (10285801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOMATSU Kenichi (70364510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KANDA Takefumi (10528673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKESHIMA Tarou (50554565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KENZAKA Tsuneaki (90437492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. FUKUI Emiko (20208341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. GOTOH Takaya (80284355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. SAKAMOTO Atsushi (80235168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 井上荘一郎 (20322399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 茂木康一 (80344919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 瀬尾憲正 (40093257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 堀田訓久 (70322401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 今野和典 (40528676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KUMADA Maki 熊田 真樹

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Rh蛋白複合体関連遺伝子ノックアウトマウスの作成とその遺伝学・生物学的解析Principal Investigator

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[Journal Article] Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI2010

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Journal Title

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[Journal Article] Regulatory SNP in the RBP4 gene modified the expression in adipocytes and associated with BMI2010

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Journal Title

Data Source

[Journal Article] Identification of a regulatory SNP in the retinol binding protein 4 gene associated with type 2 diabetes in Mongolia.2007

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Data Source

[Journal Article] An intronic variable number of tandem repeat polymotphisms of the cold-induced autoinflammatory syndrome 1(CIAS1) gene modifies gene expression and is associated with essential hypertension.2006

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[Journal Article] CATERPILLER遺伝子群のSNPタイピングによる本態性高血圧との関連解析2006

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KUMADA Maki 熊田真樹