Chuman Yoshiro 中馬吉郎

… Alternative Names

CHUMAN Yoshiro 中馬吉郎

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Researcher Number	40372263
Other IDs
Affiliation (Current)	2025: 新潟大学, 自然科学系, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 新潟大学, 自然科学系, 研究教授 2013 – 2020: 新潟大学, 自然科学系, 准教授 2014: 新潟大学, 大学院自然科学系, 准教授 2012: 北海道大学, 理学(系)研究科(研究院), 助教 2007 – 2012: Hokkaido University, 大学院・理学研究院, 助教 2006: 北海道大学, 大学院理学研究院, 助手 2004 – 2005: Hokkaido Univ., Grad.School of Sci., Inst., 大学院・理学研究科, 助手
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Functional biochemistry / Medium-sized Section 50:Oncology and related fields / Bio-related chemistry / Chemistry related to living body Except Principal Investigator Living organism molecular science / Medium-sized Section 57:Oral science and related fields / Basic Section 57020:Oral pathobiological science-related / Bioorganic chemistry / Science and Engineering
Keywords	Principal Investigator がん / ホスファターゼ / 酵素 / アプタマー / 抗がん剤 / ＤＮＡアプタマー / 核酸医薬 / 分子標的薬 / p53 / PPM1D … More / プロテインホスファターゼ / AI / 光応答性 / 核酸治療 / 刺激応答 / DNAアプタマー / 触媒機構 / シグナル伝達 / リン酸化 / 染色体不安定性 / スプライシング / 結合モチーフ / 大腸菌発現 / 阻害剤 / ペプチド / ファージディスプレイ / PP2C … More Except Principal Investigator ペプチド / 癌抑制タンパク質 / 生体分子 / 癌 / 蛋白質 / オリゴマー / フォールディング / 変異体 / ヘテロオリゴマー / マクロライド / ナノバブル / 肺炎球菌 / Streptococcus pneumoniae / MRSA / tumor suppressor protein / dominant negative / peptide / combinatorial library / heterooligomer / ドミナントネガティブ / コンビナトリアルライブラリー / バイオミネラリゼーション / ナノマテリアル / 配向化 / 多量体化 / 生物活性 / 進化 / 系統進化 / シグナル伝達 / フォールデイング / バイオテクノロジー / 構造活性相関 / 変性 / 蛍光 / β構造 / アミロイド / 構造安定性 / がん抑制タンパク質 Less

Research and development of a preventive drug for vaccine side effects using nanobubble neomacrolide
- Principal Investigator
  
  Terao Yutaka
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Niigata University
Functional optimization and establishment of comprehensive evaluation of membrane-permeable aptamers for drug development using AI technologyPrincipal Investigator
- Principal Investigator
  
  中馬吉郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Niigata University
Development of Next-Generation Platform for Light-induced DrugsPrincipal Investigator
- Principal Investigator
  
  中馬吉郎
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Niigata University
In vivo MS analysis of drug-resistant pneumococci and research on the development of new antibacterial drugs
- Principal Investigator
  
  Terao Yutaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Niigata University
Elucidation of the mechanism for auto-penetrating DNA aptamers and their application as post-antibody drugsPrincipal Investigator
- Principal Investigator
  
  Chuman Yoshiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Niigata University
Construction of MRSA-specific 3D convertible DNA antibacterial drug
- Principal Investigator
  
  Terao Yutaka
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Niigata University
Substrate identification method for protein phosphatases through the induction of enzyme-substrate intermediatePrincipal Investigator
- Principal Investigator
  
  Chuman Yoshiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Niigata University
Control of Bioreaction via Oligomerization and Orientation of Tumor Suppressor Protein p53 Tetramer
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
Study on the molecular mechanism of genome instability in the cells with overexpression of PPM1DPrincipal Investigator
- Principal Investigator
  
  CHUMAN Yoshiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Niigata University
  Hokkaido University
Stability Change of Tetrameric Structure of Tumor Suppressor Protein p53 in Mutation and Evolution, and Threshold for Loss of Tumor Suppressor Activity in Terms of Disruption of the Tetrameric Structure.
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
Analysis of splicing variant of p53-inducible phosphatase PPM1D on carcinogenesisPrincipal Investigator
- Principal Investigator
  
  CHUMAN Yoshiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hokkaido University
Inactivation of Tumor Suppressor Protein p53 by Mutations in the Tetramerization Domain and Stabilizing Methods for the Tetrameric Structure
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hokkaido University
p53誘導性ホスファターゼPPM1Dの機能解析用分子ツールとしての阻害剤開発Principal Investigator
- Principal Investigator
  
  中馬吉郎
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Hokkaido University
がん抑制タンパク質p53の四量体形成ドメインのフォールディング
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Design and development of tumor suppressor protein p53 variant that cannot form heterooligomers with the wild-type protein
- Principal Investigator
  
  SAKAGUCHI Kazuyasu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  HOKKAIDO UNIVERSITY
  Kyushu University

[Book] 発がん関連Ser/Thrホスファターゼに対する新規阻害剤と基質同定法の開発2018
- Author(s)
  八木　誠也，金子　敦巳, 山崎　一樹，吉田　拓弥, 中馬　吉郎
- Total Pages
  4
- Publisher
  BIO Clinica 北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-15K05560
[Book] 発がん関連Ser/Thrホスファターゼに対する新規阻害剤の開発2017
- Author(s)
  金子　敦巳, 中馬　吉郎
- Total Pages
  4
- Publisher
  BIO Clinica 北隆館
- ISBN
- Data Source
  KAKENHI-PROJECT-15K05560
[Journal Article] Development of Antibody-like Proteins Targeting the Oncogenic Ser/Thr Protein Phosphatase PPM1D2022
- Author(s)
  Ikeura, M., Tashiro, H., Yamagata, Y., Saito, H., Kobayashi, T., Mizunuma, M., Yamazaki, K., Baba, K. Furukawa, K. and Chuman, Y.
- Journal Title
  
  Processes
  
  Volume: 10(8) Issue: 8 Pages: 1501-1501
- DOI
  10.3390/pr10081501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24178
[Journal Article] Development of Antibody-mimetic Small Proteins Targeting Tumor-associated Phosphatase PPM1D2022
- Author(s)
  Ikeura, M., Tashiro, H., Shinada, J., Furukawa, K., and Chuman, Y.
- Journal Title
  
  Peptide Sci.
  
  Volume: 2021 Pages: 79-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24178
[Journal Article] Identification of Inhibitors for Disease related Phosphatase Scp1 Using Antibody like Adnectin.2022
- Author(s)
  Shinada, J., Yamazaki, K., Ikeura, M., Furukawa, K., and Chuman, Y. Identification of Inhibitors for Disease related Phosphatase Scp1 Using Antibody like Adnectin
- Journal Title
  
  Peptide Sci.
  
  Volume: 2021 Pages: 97-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24178
[Journal Article] 時空間的制御可能な外部刺激応答性核酸医薬の現状と応用2021
- Author(s)
  山形　優香・鈴木　未来・水沼　正昂・中馬　吉郎
- Journal Title
  
  BIO Clinica
  
  Volume: 36 (14) Pages: 79-81
- Data Source
  KAKENHI-PROJECT-19H03512
[Journal Article] Application of Mn2+-specific Biosensor Based on G-quadruplex DNA Aptamer.2021
- Author(s)
  Mizunuma, M., Kaneko, A., Watari, M., Saito, H., Banno, A., Yamagata, Y., Furukawa, K., and Chuman, Y.
- Journal Title
  
  Peptide Sci.
  
  Volume: 2020 Pages: 135-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03512
[Journal Article] Methods for Identification of Substrates/Inhibitors of FCP/SCP Type Protein Ser/Thr Phosphatases2020
- Author(s)
  Mizunuma, M., Kaneko, A., Imai, S., Furukawa, K. and Chuman, Y.
- Journal Title
  
  Processes
  
  Volume: 8（12） Issue: 12 Pages: 1598-1598
- DOI
  10.3390/pr8121598
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03512, KAKENHI-PROJECT-18J20422
[Journal Article] Development of Aptamer Based Stimuli-Responsive PPM1D Inhibitors with Cell-Penetrating Activity2020
- Author(s)
  Kaneko, A., Watari, M., Mizunuma, M., Saito, H., Furukawa, K. and Chuman, Y
- Journal Title
  
  Peptide Sci.
  
  Volume: 2019 Pages: 23-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03512
[Journal Article] Development of Specific Inhibitors for Oncogenic Phosphatase PPM1D by Using Ion-Responsive DNA Aptamer Library2020
- Author(s)
  Kaneko, A., Watari, M., Mizunuma, M., Saito, H., Furukawa, K. and Chuman, Y.
- Journal Title
  
  Catalysts
  
  Volume: 10(10) Issue: 10 Pages: 1153-1153
- DOI
  10.3390/catal10101153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03512, KAKENHI-PROJECT-18J20422
[Journal Article] Development of Novel Substrate Identification Method for Oncogenic Phosphatase PPM1D Using His107-Mutants.2020
- Author(s)
  Imai, S., Yagi, S., Ikeura, M., Furukawa, K., and Chuman, Y.
- Journal Title
  
  Peptide Sci.
  
  Volume: 2019 Pages: 75-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03512
[Journal Article] Structure-activity Relationship of Aptamer Based Ion-responsive PPM1D Inhibitor.2019
- Author(s)
  Kaneko, A., Watari, M., Furukawa, K., and Chuman, Y.
- Journal Title
  
  Peptide Sci.
  
  Volume: 2018 Pages: 100-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03512
[Journal Article] Development of Substrate Identification Method for Oncogenic PPM1D Phosphatase.2019
- Author(s)
  Yagi, S., Tashiro, H., Furukawa, K., and Chuman, Y.
- Journal Title
  
  Peptide Sci.
  
  Volume: 2018 Pages: 102-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03512
[Journal Article] Identification of a Specific Inhibitor of Human Scp1 Phosphatase Using the Phosphorylation Mimic Phage Display Method2019
- Author(s)
  Yoshida, T., Yamazaki, K., Imai, S., Banno, A., Kaneko, A., Furukawa, K. and Chuman, Y.
- Journal Title
  
  Catalysts
  
  Volume: 9 Issue: 10 Pages: 842-842
- DOI
  10.3390/catal9100842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03512, KAKENHI-PROJECT-18J20422
[Journal Article] Development of a Substrate Identification Method for Human Scp1 Phosphatase Using Phosphorylation Mimic Phage Display2018
- Author(s)
  Otsubo Kodai、Yoneda Takashi、Kaneko Atsushi、Yagi Seiya、Furukawa Kazuhiro、Chuman Yoshiro
- Journal Title
  
  Protein & Peptide Letters
  
  Volume: 25 Issue: 1 Pages: 76-83
- DOI
  10.2174/0929866525666171206114913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05560
[Journal Article] Inhibition of protein phosphatase PPM1D enhances retinoic acid-induced differentiation in human embryonic carcinoma cell line2018
- Author(s)
  Ogasawara Sari、Chuman Yoshiro、Michiba Takahiro、Kamada Rui、Imagawa Toshiaki、Sakaguchi Kazuyasu
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 6 Pages: 471-477
- DOI
  10.1093/jb/mvy119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J01123, KAKENHI-PROJECT-19H03512
[Journal Article] Characterization of Enzymatic Activity of FCP/SCP Type Ser/Thr Phosphatase Family2017
- Author(s)
  Yagi, S., Yoneda, T., Otsubo, K., Furukawa, K., and Chuman, Y.
- Journal Title
  
  Peptide Sci.
  
  Volume: 2016 Pages: 225-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05560
[Journal Article] Characterization of Enzymatic Activity of FCP/SCP Type Ser/Thr Phosphatase Family2017
- Author(s)
  Yagi, S., Yoneda, T., Otsubo, K., Furukawa, K., and Chuman, Y
- Journal Title
  
  Peptide Sci
  
  Volume: 2016 Pages: 225-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05560
[Journal Article] Inhibition of Oncogenic Phosphatase PPM1D by G-quadruplex DNA Aptamer in Cancer Cells2017
- Author(s)
  Kaneko, A., Furukawa, K., Sakaguchi, K., and Chuman, Y.
- Journal Title
  
  Peptide Sci
  
  Volume: 2016 Pages: 23-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05560
[Journal Article] Novel Inhibitors Targeting PPM1D Phosphatase Potently Suppress Cancer Cell Proliferation.2015
- Author(s)
  Ogasawara, S., Kiyota, Y., Chuman, Y., Kowata, A., Yoshimura, F., Tanino, K., Kamada, R., and Sakaguchi, K.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 19 Pages: 6246-6249
- DOI
  10.1016/j.bmc.2015.08.042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K05560, KAKENHI-PLANNED-15H05842, KAKENHI-PROJECT-15H03806
[Journal Article] Development of the Novel Substrate Identification Methodology for Ser/Thr Phosphatases Using Phosphorylation Mimic Phage Display Library.2015
- Author(s)
  Otsubo, K., Furukawa K, Chuman, Y.
- Journal Title
  
  Peptide Sci.
  
  Volume: 2016 Pages: 271-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K05560
[Journal Article] Function of Proto-oncogene Product PPM1D and Development of PPM1D Inhibitors for Cancer Chemotherapy.2015
- Author(s)
  Kamada, R.; Chuman, Y.; Kozakai, Y.; Sakaguchi, K.
- Journal Title
  
  Seikagaku. The Journal of Japanese Biochemical Society
  
  Volume: 87 Pages: 531-538
- NAID
  40020649963
- Open Access
- Data Source
  KAKENHI-PROJECT-15K05560
[Journal Article] Synthesis of yellow and red fluorescent 1,3a,6a-triazapentalenes and the theoretical investigation of their optical properties2015
- Author(s)
  Kosuke Namba, Ayumi Osawa, Akira Nakayama, Akane Mera, Fumi Tano, Yoshiro Chuman, Eri Sakuda, Tetsuya Taketsugu, Kazuyasu Sakaguchi, Noboru Kitamura, Keiji Tanino
- Journal Title
  
  Chemical Science
  
  Volume: 6 Issue: 2 Pages: 1083-1093
- DOI
  10.1039/c4sc02780a
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J02457, KAKENHI-PROJECT-23750141, KAKENHI-PROJECT-24310162, KAKENHI-PROJECT-24570146, KAKENHI-PROJECT-26560449, KAKENHI-PROJECT-15K05560, KAKENHI-PROJECT-15K06563, KAKENHI-PLANNED-15H05842, KAKENHI-PUBLICLY-26102734, KAKENHI-PUBLICLY-26110501, KAKENHI-PROJECT-15H03806
[Journal Article] Secreted Frizzled-Related Protein Potentiation versus Inhibition of Wnt3a/β-catenin Signaling2014
- Author(s)
  1. Xaviera, C.P., Melikova, M., Chuman, Y., Üren, A., Baljinnyam, B., Rubin, J.S.
- Journal Title
  
  Cell. Signal
  
  Volume: 26 Issue: 1 Pages: 94-101
- DOI
  10.1016/j.cellsig.2013.09.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24570146
[Journal Article] Formation of Functionalized Nanowires Based on Control of Self-Assembly Using Multiple Modified Amyloid Peptides2013
- Author(s)
  Hiroki Sakai, Ken Watanabe, Yuya Asanomi, Yumiko Kobayashi, Yoshiro Chuman, Lihong Shi, Takuya Masuda, Thomas Wyttenbach, Michael T. Bowers, Kohei Uosaki, and Kazuyasu Sakaguchi
- Journal Title
  
  Adv. Funct. Mater.
  
  Volume: 23 Pages: 4881-4887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310152
[Journal Article] Effects of E/Z Configuration of Fluoroalkene-containing HDAC Inhibitors on Selectivity for HDAC Isoforms2013
- Author(s)
  Yoshiro Chuman, Mariko Ueyama, Satoshi Sano, Fei Wu, Yuhei Kiyota, Takayoshi Higashi, Satoshi Osada, and Kazuyasu Sakaguchi
- Journal Title
  
  Chem. Lett.
  
  Volume: 42 Issue: 8 Pages: 833-835
- DOI
  10.1246/cl.130243
- NAID
  10031189265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310152, KAKENHI-PROJECT-24570146
[Journal Article] Formation of Functionalized Nanowires by Control of Self-Assembly Using Multiple Modified Amyloid Peptides2013
- Author(s)
  Sakai H, Watanabe K, Asanomi Y, Kobayashi Y, Chuman Y, Shi L, Masuda T, Wyttenbach T, Bowers MT, Uosaki K, Sakaguchi K
- Journal Title
  
  Advanced Functional Materials
  
  Volume: 23 Issue: 39 Pages: 4881-4887
- DOI
  10.1002/adfm.201300577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07100, KAKENHI-PROJECT-24570146
[Journal Article] Repression of p53transcriptional activity by inhibitory peptide via heterotetramerization2012
- Author(s)
  J. Wada, R. Kamada, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2011 Pages: 301-302
- NAID
  10030204437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Inhibition of tumor suppressor protein p53-dependent transcription by a tetramerization domain peptide via hetero-oligomerization2012
- Author(s)
  J. Wada, R. Kamada, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Bioorg Med Chem. Lett
  
  Volume: 22 Issue: 8 Pages: 2780-2783
- DOI
  10.1016/j.bmcl.2012.02.085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133, KAKENHI-PROJECT-23651210
[Journal Article] Nanostructure formed by biomineralization peptide oligomerized via p53 tetramerization2012
- Author(s)
  T. Sakaguchi, R. Kamada, Y. Chuman, and K.Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2011 Pages: 345-346
- NAID
  10030204547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] A small molecule inhibitor of p53-inducible protein phosphatase PPM1D2012
- Author(s)
  八木寛陽
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: VOL.22 Issue: 1 Pages: 729-732
- DOI
  10.1016/j.bmcl.2011.10.084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01998, KAKENHI-PROJECT-21310133, KAKENHI-PROJECT-22710206, KAKENHI-PROJECT-23651210, KAKENHI-PROJECT-24350018, KAKENHI-PROJECT-24570146, KAKENHI-PLANNED-21106010
[Journal Article] Phosphatase assay for multi-phosphorylated substrates using phosphatase specific-motif antibody2011
- Author(s)
  Chuman, Y., Iizuka, K., Honda, T., Onoue, H., Shimohigashi, Y., Sakaguchi, K.
- Journal Title
  
  J.Biochem. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] sFRP-1 binds via its netrin-related motif to the N-module of thrombospondin-1 and blocks thrombospondin-1 stimulation of MDA-MB-231 breast carcinoma cell adhesion and migration.2011
- Author(s)
  Martin-Manso, G., Calzada, M.J., Chuman, Y., Sipes, J.M., Xavier, C.P., Wolf, V., Kuznetsova, S.A., Rubin, J.S., Roberts, D.D.
- Journal Title
  
  Arch.Biochem.Biophys. 509(2)
  
  Pages: 147-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Low Threshold of Destabilization for Loss of Tumor Suppressor Activity of p53 : A Quantitative Analysis of p53 Tetramerization Domain Mutants2011
- Author(s)
  R. Kamada, T. Nomura, Y. Chuman, T.Imagawa C.W. Anderson, and K. Sakaguchi
- Journal Title
  
  Peptide Sci
  
  Volume: 2010 Pages: 149-150
- NAID
  10028237634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Probing Phenylalanine Environments in Oligomeric Structures Phenylalanine with Pentafluorophenylalanine and Cyclohexylalanine2011
- Author(s)
  T. Nomura, R. Kamada, I. Ito, K. Sakamoto, Y. Chuman, K. Ishimori, Y. Shimohigashi, and K. Sakaguchi
- Journal Title
  
  Biopolymers
  
  Volume: 95 Issue: 6 Pages: 410-419
- DOI
  10.1002/bip.21594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133, KAKENHI-PROJECT-22221005
[Journal Article] Probing phenylalanine environments in oligomeric structures with pentafluorophenylalanine and cyclohexylalanine.2011
- Author(s)
  Nomura, T., Kamada, R., Ito, I., Sakamoto, K., Chuman, Y., Ishimori, K., Shimohigashi, Y., Sakaguchi, K.
- Journal Title
  
  Biopolymers 95(6)
  
  Pages: 410-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Repression of p53 transcriptional activity by p53 tetramerization domain peptide containing PTD and NLS domain2011
- Author(s)
  J. Wada, R. Kamada, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2010 Pages: 95-96
- NAID
  10028237399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Drastic Effects on Fibril Formation of Amyloid-beta Peptides by the Addition of Amino Acid Residue Units to the Termini2010
- Author(s)
  Asanomi, Y., Kobayashi, Y, Sakai, H., Masuda, T., Chen, X., Chuman, Y., Uosaki, K., Sakaguchi, K.
- Journal Title
  
  Protein Pept.Lett. 17(4)
  
  Pages: 458-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Inhibition of p53 by Introducing Tetramerization Domain Peptide Fused with Polyvalent Cationic Sequence into cells2010
- Author(s)
  R. Kamada, S. Ohshima, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2009 Pages: 319-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Characterization of Two Novel and Potent Inhibitors Specific for p53-Inducible Protein Phosphatase PPM1D.2010
- Author(s)
  Yagi, H., Chuman, Y., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2009
  
  Pages: 455-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Development of Probed-SCAP Directed at Thiol Groups.2010
- Author(s)
  Watanabe, K., Sakai, H., Chen, X., Chuman, Y, Sakaguchi, K.
- Journal Title
  
  Peptide Science 2009
  
  Pages: 407-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Biomineralization Activity of Multivalent min TBP-1 Peptide Mediated by p53 Tetramerization Domain2010
- Author(s)
  T. Sakaguchi, R. Kamada, T. Nomura, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Peptide Sci.
  
  Volume: 2009 Pages: 411-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Inhibition of p53 by Introducing Tetramerization Domain Peptide Fused with Polyvalent Cationic Sequence into Cells.2010
- Author(s)
  Kamada, R., Oshima, S., Chuman, Y., Imagawa, T., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2009
  
  Pages: 319-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Biomineralization Activity of Multivalent minTBP-1 Peptide Mediated by p53 Tetramerization Domain.2010
- Author(s)
  Sakaguchi, T., Kamada, R., Nomura, T., Chuman, Y., Imagawa, T., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2009
  
  Pages: 411-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Fluoroalkene Modification of Mercaptoacetamide-based Histone Deacetylase Inhibitors2010
- Author(s)
  Osada, S., Sano, S., Ueyama, M., Chuman, Y., Kodama, H., Sakaguchi, K.
- Journal Title
  
  Bioorg.Med.Chem. 18(2)
  
  Pages: 605-611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Enhancement of transcriptional activity of mutant p53 tumor suppressor protein through stabilization of tetramer formation by calix[6]arene derivatives2010
- Author(s)
  Kamada, R., Yoshino, W., Nomura, T., Chuman, Y., Imagawa, T., Suzuki, T., Sakaguchi, K.
- Journal Title
  
  Bioorg.Med.Chem Lett. 20(15)
  
  Pages: 4412-4415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D2009
- Author(s)
  Chuman et.al.
- Journal Title
  
  Peptide Science 2008
  
  Pages: 531-532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Oxidation of methionine residue at hydrophobic core destabilizes p53 tetrameric structure2009
- Author(s)
  T. Nomura, R. Kamada, I. Ito, Y.Chuman, Y. Shimohigashi, K. Sakaguchi
- Journal Title
  
  Biopolymers 91(1)
  
  Pages: 78-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Effects of tumor-associated mutations in the p53 tetramerization domain on oligomerization state and transcriptional activity.2009
- Author(s)
  Kamada, R., Terai, T., Nomura, T., Chuman, Y, Imagawa, T., Sakaguchi, K.
- Journal Title
  
  Adv.Exp.Med.Biol. 611
  
  Pages: 567-568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Oxidation of methionine residue at hydrophobic core destabilizes p53 tetrameric structure2009
- Author(s)
  Nomura, T., Kamada, R., Ito, I., Chuman, Y, Shimohigashi, Y, Sakaguchi, K.
- Journal Title
  
  Biopolymers 91(1)
  
  Pages: 78-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Effects of tumor-associated mutations in the p53 tetramerization domain on oligomerization state and transcriptional activity2009
- Author(s)
  R. Kamada, T. Terai, T. Nomura, Y. Chuman, T. Imagawa, and K. Sakaguchi
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 611 Pages: 567-8
- DOI
  10.1007/978-0-387-73657-0_249
- ISBN
  9780387736563, 9780387736570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310133
[Journal Article] Thermal Stability of p53 Tetramerization Domain Peptides Derived from Various Species2009
- Author(s)
  T. Nomura, R. Kamada, Y. Chumanand and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2008
  
  Pages: 35-36
- NAID
  10027165876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D.2009
- Author(s)
  Y. Chuman
- Journal Title
  
  Peptide Science 2008
  
  Pages: 531-532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D.2009
- Author(s)
  Chuman, Y., Kurihashi, W., Mizukami, Y., Nashimoto, T., Yagi, H., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2008
  
  Pages: 531-532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Effects of tumor-associated mutations in thep53 tetramerization domain onoligomerization state and transcriptionalactivity2009
- Author(s)
  R. Kamada, T. Terai, T. Nomura, Y. Chuman, T. Imagawa, K. Sakaguchi
- Journal Title
  
  Adv. Exp.Med. Biol 611
  
  Pages: 567-568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Identification of Novel Chemical Inhibitors for p53-Inducible Protein Phosphatase PPM1D.2009
- Author(s)
  Yagi, H., Chuman, Y., Yoshimura, F., Tanino, K., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2008
  
  Pages: 385-386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] PPMID430, a Novel Alternative Splicing Variant of the Human PPM1D, can Dephosphorylate p53 and Exhibits Specific Tissue Expression2009
- Author(s)
  Y. Chuman
- Journal Title
  
  J. Biochem. 145
  
  Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Extremely Long Nanofibrils of Functionalized Structure-Controlled-Amyloid Peptides Derived from Transthyretin.2009
- Author(s)
  Sakai, H., Asanomi, Y., Kobayashi, Y., Chen, X., Chuman, Y., Masuda, T., Uosaki, K., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2008
  
  Pages: 465-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Thermal Stability of p53 Tetramerization Domain Pe4ptides Derived from Various Species.2009
- Author(s)
  Nomura, T., Kamada, R., Chuman, Y., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2008
  
  Pages: 35-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D, can Dephosphorylate p53 and Exhibits Specific Tissue Expression2009
- Author(s)
  Chuman, Y., Kurihashi, W., Mizukami, Y., Nashimoto, T., Yagi, H., Sakaguchi, K.
- Journal Title
  
  J.Biochem. 145(1)
  
  Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D, can Dephosphorylate p53 and Exhibits Specific Tissue Expression2009
- Author(s)
  Chuman, et al.
- Journal Title
  
  J Biochem. 145
  
  Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D, can Dephosphorylate p53 and Exhibits Specific Tissue Expression2009
- Author(s)
  Chuman et.al.
- Journal Title
  
  J Biochem 145
  
  Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Characterization of the Active Site and a Unique Uncompetitive Inhibitor of the PPM1-type Protein Phosphatase PPM1D2008
- Author(s)
  Chuman, Y, et. al.
- Journal Title
  
  Protein Pept. Lett. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17750148
[Journal Article] Correlation between Expression Level in E.coli and Stability of Oligomeric Structure ofthe p53 Tetramerization Domain2008
- Author(s)
  H. Miyazaki, R. Kamada, T. Nomura, Y. Chuman, T.Imagawa and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2007
  
  Pages: 317-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Differential Recognition of PhosphorylatedTransactivation Domains of p53 by Differentp300 Domains2008
- Author(s)
  S. Polley, S. Guha, N.S. Roy,S. Kar, K. Sakaguchi, Y. Chuman, V.Swaminathan and S. Roy
- Journal Title
  
  J. Mol. Biol. 376
  
  Pages: 8-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Characterization of the Active Site and a Unique Uncompetitive Inhibitor of the PPM1-type Protein Phosphatase PPM1D2008
- Author(s)
  Y. Chuman
- Journal Title
  
  Protein & Peptide Lett. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Structural Photomodulation of Peptides with Azobenzoate Derivative in Peptide Backbone.2008
- Author(s)
  R. Kamada, K. Fukuda, H. Miyazaki, T.Nomura, Y. Chuman, T. Imagawa, K. Tanino and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2007
  
  Pages: 447-448
- NAID
  10021907298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Structural Photomodulation of Peptides with Azobenzoate Derivative in Peptide Backbone.2008
- Author(s)
  Kamada, R., Fukuda, K., Miyazaki, H., Nomura, T., Chuman, Y., Imagawa, T., Tanino, K., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2007
  
  Pages: 447-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Correlation of Oligomeric Structure and Transcriptional Activity of p53 Mutants.2008
- Author(s)
  Kamada, R, Terai, T., Nomura, T., Chuman, Y, Imagawa, T., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2007
  
  Pages: 69-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Correlation between Expression Level in E. coli and Stability of Oligomeric Structure of the p53 Tetramerization Domain.2008
- Author(s)
  Miyazaki, H., Kamada, R., Nomura, T., Chuman, Y., Imagawa, T., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2007
  
  Pages: 317-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Differential Recognition of Phosphorylated Transactivation Domains of p53 by Different p300 Domains2008
- Author(s)
  Polley, S., Guha, S., Roy, N.S., Kar, S., Sakaguchi, K., Chuman, Y., Swaminathan, V., Roy, S.
- Journal Title
  
  J.Mol.Biol. 376
  
  Pages: 8-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Correlation of Oligomeric Structure and Transcriptional Activity of p53 Mutants2008
- Author(s)
  R. Kamada, T. Terai, T. Nomura, Y. Chuman, T.Imagawa and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2007
  
  Pages: 69-70
- NAID
  10021906623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Characterization of the Active Site and a Unique Uncompetitive Inhibitor of the PPM1-tvpe Protein Phosphatase PPM1D2008
- Author(s)
  Y. Chuman
- Journal Title
  
  Protein Pept. Lett. 15
  
  Pages: 938-948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Screening of Peptides to Stabilize the p53 Tetramer Formation from Phage Displayed Library2008
- Author(s)
  T. Nomura, R. Kamada, Y. Chuman and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2007
  
  Pages: 315-316
- NAID
  10021907074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Characterization of the Active Site and a Unique Uncompetitive Inhibitor of the PPM1-type Protein Phosphatase PPM1D2008
- Author(s)
  Chuman, Y., Yagi, H., Fukuda, T., Nomura, T., Matsukizono, M., Shimohigashi, Y., Sakaguchi K.
- Journal Title
  
  Protein Pept.Lett. 15
  
  Pages: 938-948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Screening of Peptides to Stabilize the p53 Tetramer Formation from Phage Displayed Library.2008
- Author(s)
  Nomura, T., Kamada, R., Chuman, Y., Sakaguchi, K.
- Journal Title
  
  Peptide Science 2007
  
  Pages: 315-316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Characterization of the Active Site and a Unique Uncompetitive Inhibitor of the PPM1-type Protein Phosphatase PPM1D2008
- Author(s)
  Chuman et.al.
- Journal Title
  
  Protein Pept. Lett 15
  
  Pages: 938-948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770095
[Journal Article] Thermodynamic Stability of Mutant p53 Tetramerization Domain Peptides Associated with Human Tumors2007
- Author(s)
  R. Kamada, T. Nomura, Y. chuman, T. Imagawa and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2006
  
  Pages: 131-132
- NAID
  10020530042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Stabilization of p53 Tetrameric Structure by Polyol Compounds2007
- Author(s)
  T. Nomura, Y. Chuman and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2006
  
  Pages: 131-132
- NAID
  10020529267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Fibrillar and Granular Aggregation of G334V Mutant p53 Tetramer Peptide. Y. Asanomi, Y. Higashimoto2006
- Author(s)
  Y. Asanomi, Y. Higashimoto, Y. Chuman, S. Kaya, T. Imagawa and K. Sakaguchi
- Journal Title
  
  Peptide Sci 2005
  
  Pages: 397-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Analysis of Stabilization by Substituti on of Cyclohexylalanine for Phe341 in Hydrophobic Core of p53 Tetramer.2006
- Author(s)
  T. Nomura, K. Sakamoto, Y. Kasai, Y. Chuman, K. Ishimori and K. Sakaguchi
- Journal Title
  
  Peptide Science 2005
  
  Pages: 399-402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310140
[Journal Article] Identification of Novel Binding Motif for Secreted Frizzled-Related Protein-12005
- Author(s)
  Chuman, Y.
- Journal Title
  
  Peptide Science 2004
  
  Pages: 91-94
- Data Source
  KAKENHI-PROJECT-17750148
[Patent] 核酸アプタマー2020
- Inventor(s)
  中馬　吉郎，金子　敦巳，亘　美佑
- Industrial Property Rights Holder
  中馬　吉郎，金子　敦巳，亘　美佑
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03512
[Patent] 細胞内分子を標的とした細胞膜透過型核酸アプタマー2020
- Inventor(s)
  中馬　吉郎，金子　敦巳，亘　美佑
- Industrial Property Rights Holder
  中馬　吉郎，金子　敦巳，亘　美佑
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03512
[Patent] 細胞内分子を標的とした細胞膜透過型核酸アプタマー2019
- Inventor(s)
  中馬　吉郎，金子　敦巳，亘　美佑
- Industrial Property Rights Holder
  中馬　吉郎，金子　敦巳，亘　美佑
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03512
[Patent] プロテインホスファターゼ阻害剤2008
- Inventor(s)
  坂口和靖, 谷野圭持, 中馬吉郎, 吉村文彦, 八木寛陽
- Industrial Property Number
  2008-262646
- Filing Date
  2008-10-09
- Data Source
  KAKENHI-PROJECT-18310140
[Patent] プロテインホスファターゼ阻害剤2008
- Inventor(s)
  坂口和靖、谷野圭持、中馬吉郎、吉村文彦、八木寛陽
- Industrial Property Rights Holder
  LCIP
- Industrial Property Number
  2008-262646
- Filing Date
  2008-10-09
- Data Source
  KAKENHI-PROJECT-20770095
[Patent] p53翻訳後修飾部位を特異的に認識するーナル抗体、及びその抗体を含む修飾部位測定キット2006
- Inventor(s)
  坂口和靖, 中馬吉郎, 明日山康生, 松木園美穂
- Industrial Property Number
  2007-511193
- Filing Date
  2006-03-31
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] 疾患関連タンパク質Scp1に対する特異的IRDAptamerの機能解析2023
- Author(s)
  菅原諒太，水沼正昂，鈴木未来，山形優香，古川和広，中馬吉郎
- Organizer
  第１３回　UGCE　シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] 新規創薬モダリティ：IRDAptamerの開発と応用2023
- Author(s)
  中馬吉郎
- Organizer
  医療・診断の化学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] 抗体模倣分子のloop置換体を用いた疾患関連酵素Scp1阻害剤の開発2023
- Author(s)
  小林　環，品田純輝，鈴木未来，山形優香，古川和広，中馬吉郎
- Organizer
  第１３回　UGCE　シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] Development of SARS-CoV-2 Spike Protein-Binding Molecules Using G4-Based DNA Aptamer: IRDAptamer2023
- Author(s)
  Masataka Mizunuma, Yuka Yamagata, Mirai Suzuki, Shingo Tanaka, Kazuhiro Furukawa, and Yoshiro Chuman
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] 細胞内を標的可能な新規創薬プラットホームの開発2023
- Author(s)
  中馬吉郎
- Organizer
  みちのくGAPファンド DemoDay
- Invited
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] 発がん関連タンパク質PPM1Dにおける特異的loopの機能解析2023
- Author(s)
  原侑希1・齊藤輝1・古賀信康2・古川和広1・中馬吉郎
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] Development of a Method to Control the Function of G4-based DNA Aptamer; IRDAptamer2023
- Author(s)
  Mirai Suzuki, Yuka Yamagata, Masataka Mizunuma, Kazuhiro Furukawa, Yoshiro Chuman
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] グアニン四重鎖IRDAptamerに対する高感度検出ツールの開発2022
- Author(s)
  田中智貴, 坂野彰則, 山形優香, 古川和広2, 中馬吉郎
- Organizer
  第61回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] 細胞内を標的可能な新規創薬モダリティ：IRDAptamerの開発2022
- Author(s)
  中馬吉郎
- Organizer
  第4回 BVAバイオインターフェース
- Invited
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] 膜透過性DNA アプタマー： IRDAptamer を用いた創薬モダリティの開発2022
- Author(s)
  山形優香、金子敦巳、坂野彰則、水沼正昂、古川和広、○中馬吉郎
- Organizer
  第95回　日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] 細胞内を標的可能な新規創薬モダリティの開発2022
- Author(s)
  中馬吉郎
- Organizer
  第３回BVA創薬研究会
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] DEVELOPMENT OF MEMBRANE-PERMEABLE DNA APTAMERS TARGETING ONCOGENIC SER/THR PROTEIN PHOSPHATASE PPM1D2022
- Author(s)
  Yoshiro Chuman, Yuuka Yamagata, Atsushi Kaneko, Akinori Bannno, Masataka Mizunuma, Kazuhiro Furukawa
- Organizer
  The Protein phosphatase conference jointed by FASEB and JAPPR
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] 新規創薬モダリティIRDAptamer の機能制御法の開発2022
- Author(s)
  鈴木未来, 山形優香,古川和広, 中馬吉郎
- Organizer
  第61回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] Image Classification of Cancer Cells Treated with IRDAptermer2022
- Author(s)
  Rahman Rawnak Mim, Yuuka YAMAGATA, Yoshiro CHUMAN, and Shogo MURAMATSU
- Organizer
  映像情報メディア学会 ITE Technical Group Submission System
- Data Source
  KAKENHI-PROJECT-23K24178
[Presentation] Ion-responsive DNA Aptamer (IRDAptamer) drugs targeting intercellular oncogenic protein phosphatase PPM1D2021
- Author(s)
  Atsushi Kaneko, Yuuka Yamagata, Mirai Suzuki, Masataka Mizunuma, Kazuhiro Furukawa, 〇Yoshiro Chuman
- Organizer
  日本核酸医薬学会　第6回年会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] イオン刺激応答性DNAアプタマー: IRDAptamerの膜透過メカニズムの解明2021
- Author(s)
  〇山形優香,　坂野彰則,　齊藤輝,　金子敦巳,　古川和広,　中馬吉郎
- Organizer
  第10回日本プロテインホスファターゼ研究会学術集会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] Development of Novel Mn2+-specific Sensor using G-quadruplex DNA Aptamer2021
- Author(s)
  〇Masataka Mizunuma, Atsushi Kaneko, Kazuhiro Furukawa, Yoshiro Chuman
- Organizer
  第44回　日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] 脱リン酸化酵素PPM1Dの触媒活性における特異的loopの機能解明2021
- Author(s)
  〇齊藤輝, 伊東孝祐, 古川和広, 中馬吉郎
- Organizer
  第12回 UGCEシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] 発がんホスファターゼPPM1D特徴的loopの酵素活性における分子基盤解明2021
- Author(s)
  〇齊藤輝，伊東孝祐，古川和広，中馬吉郎
- Organizer
  第61回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] FCP/SCPタイプホスファターゼの酵素活性発現における末端領域の機能解析2021
- Author(s)
  〇田中信伍，石動駿樹, 古川和広，中馬吉郎
- Organizer
  第61回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] 発がん関連酵素Scp1結合IRDAptamerの同定と結合特性評価2020
- Author(s)
  坂野彰則,中馬吉郎
- Organizer
  ユビキタスグリーンケミカルエネルギー連携教育研究センター第11 回研究シンポジウム
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] 発がん関連ホスファターゼPPM1Dを標的とした膜透過性DNAアプタマーの開発2020
- Author(s)
  中馬　吉郎
- Organizer
  第43回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] Identification of the Binding Molecules for Disease-related Proteins Using Adn-based Phage Display Libraries2020
- Author(s)
  Yoshiro Chuman
- Organizer
  The 18th AKABORI Conference 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] 刺激応答性DNAアプタマー(IRDAptamer)を用いた疾患関連ホスファターゼ阻害剤の開発2020
- Author(s)
  中馬　吉郎
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] Application Of Mn2+-Specific Biosensor Based on G-Quadruplex DNA Aptamer2020
- Author(s)
  Masataka Mizunuma, Atsushi Kaneko, Miyuu Watari, Hikaru Saito, Akinori Banno, Yuka Yamagata, Kazuhiro Furukawa and Yoshiro Chuman
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] Specific Inhibitors for Oncogenic Protein Phosphatase PPM1D Using G-quadruplex-based DNA aptamer library2020
- Author(s)
  Yoshiro Chuman
- Organizer
  14th International Conference on Protein Phosphatase
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] Structure-activity Relationship and Intracellular Function of Ion-responsive DNA Aptamer against Oncogenic Phosphatase PPM1D2019
- Author(s)
  Atsushi Kaneko, Miyuu Watari, Masataka Mizunuma, Kazuhiro Furukawa, and Yoshiro Chuman
- Organizer
  2019 Taiwan-Japan Bilateral Conference on Phosphatase (4th)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] 生体内の金属イオンを高感度に検出可能なDNAアプタマーの探索と応用2019
- Author(s)
  水沼正昂, 亘美佑, 金子敦巳, 古川和広, 中馬吉郎
- Organizer
  第60回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] Development of Aptamer Based Stimuli-Responsive PPM1D Inhibitors with Cell-Penetrating Activity2019
- Author(s)
  Atsushi Kaneko, Miyuu Watari, Masataka Mizunuma, Hikaru Saito, Kazuhiro Furukawa and Yoshiro Chuman
- Organizer
  第56回ペプチド学会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] Identification of Specific Inhibitors for Oncogenic Protein Phosphatase PPM1D Using Ion-responsive DNA Aptamer (IRDAptamer) Library2019
- Author(s)
  Yoshiro Chuman、Miyuu Watari, Masataka Mizukami, Kazuhiro Furukawa、Atsushi Kaneko
- Organizer
  第42回　分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] 副作用軽減を指向したイオン応答性DNAアプタマー（IRDAptamer)薬剤の開発2019
- Author(s)
  中馬　吉郎
- Organizer
  日本核酸医薬学会　第5回年会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] イオン応答性DNAアプタマーを用いた発がんホスファターゼPPM1Dの機能制御2019
- Author(s)
  亘美佑, 金子敦巳, 水沼正昂, 古川和広, 中馬吉郎
- Organizer
  第60回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] イオン応答性PPM1D阻害剤の細胞内機能解析と構造活性相関解析2019
- Author(s)
  金子敦巳,　亘美佑,　水沼正昂,　古川和広,　中馬吉郎
- Organizer
  第9回日本プロテインホスファターゼ研究会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] Development of Highly Sensitive Ion Sensor Using Rare-metal Trapping DNA Aptamer2019
- Author(s)
  Masataka Mizunuma, Atsushi Kaneko,1 Miyuu Watari, Hikaru Saito,　Kazuhiro Furukawa, Yoshiro Chuman
- Organizer
  第100回日本化学会
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] Construction of Structurally-Controlled Platform for Identification of Specific Inhibitors against Oncogenic Ser/Thr Protein Phosphatases2019
- Author(s)
  Yoshiro Chuman
- Organizer
  2019 Taiwan-Japan Bilateral Conference on Phosphatase (4th)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03512
[Presentation] 発がん関連脱リン酸化酵素を標的とした阻害剤と新規基質同定法の開発2018
- Author(s)
  中馬　吉郎
- Organizer
  N-Hybrid conference
- Invited
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 発がんホスファターゼPPM1Dを標的とした新規基質トラップ変異体の開発2018
- Author(s)
  八木誠也,古川和広, 中馬吉郎
- Organizer
  N-Hybrid conference
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] Structure-activity Relationship Analysis of Ion-responsive DNA Aptamer Targeting Oncogenic Phosphatase PPM1D2017
- Author(s)
  Atsushi Kaneko, Masatoshi Eguchi, Kazuhiro Furukawa, Yoshiro Chuman
- Organizer
  The 3rd Japan-Taiwan Bilateral Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] イオン応答性核酸ライブラリを用いた発がんホスファターゼ機能制御法の開発2017
- Author(s)
  金子敦巳,　古川和広,　中馬吉郎
- Organizer
  第58回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] Development of the Novel Substrate Identification Method for Scp1 Phosphatase Using Peptide Phage Library with AlF4-2017
- Author(s)
  Kazuki Yamazaki, Kodai Otsubo, Takashi Yoneda, Kazuhiro Furukawa,　Yoshiro Chuman
- Organizer
  The 3rd Japan-Taiwan Bilateral Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] Development of Novel Substrate-trapping Mutants for Oncogenic Ser/Thr Protein Phosphatase PPM1D.2017
- Author(s)
  Seiya Yagi, Kazuhiro Furukawa, Yoshiro Chuman
- Organizer
  The 3rd Japan-Taiwan Bilateral Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 立体制約型抗体模倣分子を用いたファージライブラリーの構築と応用2017
- Author(s)
  山﨑一樹,　馬塲勁典,　古川和広,　中馬吉郎
- Organizer
  第58回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] Development of substrate-trapping mutant to identify the novel substrates of oncogenic protein phosphatase PPM1D2017
- Author(s)
  Seiya Yagi, Kazuhiro Furukawa, and Yoshiro Chuman
- Organizer
  ユビキタスグリーンケミカルエネルギー連携教育研究センター第７回研究シンポジウム
- Place of Presentation
  新潟大学（新潟県新潟市）
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 基質トラップ変異体を用いたがん関連ホスファターゼPPM1Dに対する新規基質同定法の開発2017
- Author(s)
  八木誠也,古川和広, 中馬吉郎
- Organizer
  第58回新潟生化学懇話会
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 脱リン酸化酵素SCPアイソフォームの酵素特性解析2017
- Author(s)
  石動駿樹, 八木誠也, 古川和広, 中馬吉郎
- Organizer
  「ユビキタスグリーンケミカルエネルギー連携教育研究センター」第8回研究シンポジウム
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] Role of Ser/Thr Phosphatase PPM1D through the Down-regulation of TOP2A on Genome Instability2017
- Author(s)
  Fumiya Suzuki, Sari Ogasawara, Kazuhiro Furukawa, Kazuyasu Sakaguchi, and Yoshiro Chuman
- Organizer
  The 3rd Japan-Taiwan Bilateral Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 金属錯体を用いた疾患関連脱リン酸化酵素に対する新規基質の探索2017
- Author(s)
  吉田拓弥, 米田崇史, 大坪広大, 古川和広, 中馬吉郎
- Organizer
  「ユビキタスグリーンケミカルエネルギー連携教育研究センター」第8回研究シンポジウム
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] イオン刺激応答性DNAアプタマーを母体とした発がんタンパク質阻害剤の開発2017
- Author(s)
  中馬吉郎、金子敦巳，古川和広
- Organizer
  日本核酸医薬学会大3回年会
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] Development of Specific Inhibitors for Oncogenic PPM1D Phosphatase Using Rigid-scaffold Structural Libraries2017
- Author(s)
  Atsushi, Kaneko, Kazuki Yamazaki, Seiya Yagi, Kazuhiro Furukawa, Yoshiro Chuman
- Organizer
  The 3rd Japan-Taiwan Bilateral Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 抗体模倣低分子タンパク質を用いたファージライブラリの構築2017
- Author(s)
  山﨑一樹, 馬塲勁典, 古川和広, 中馬吉郎
- Organizer
  「ユビキタスグリーンケミカルエネルギー連携教育研究センター」第8回研究シンポジウム
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 酵素-基質複合体誘導によるSer/Thrホスファターゼ基質同定法の開発と応用2016
- Author(s)
  中馬　吉郎
- Organizer
  第89回日本生化学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] リン酸化模倣ファージディスプレイによるSer/Thrホスファターゼ基質同定法の開発2016
- Author(s)
  大坪広大、米田崇史、古川和広、中馬吉郎
- Organizer
  第6回グリーンケミストリー研究会
- Place of Presentation
  新潟大学（新潟市）
- Year and Date
  2016-03-15
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] リン酸化ミミック分子によるSer/Thrプロテインホスファターゼ基質同定法の開発2016
- Author(s)
  大坪広大, 古川和広, 中馬吉郎
- Organizer
  第7回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  自然科学研究機構（岡崎市）
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] Screening of binding molecules for Ser/Thr phosphatases from rigid structural libraries2016
- Author(s)
  Yoshiro Chuman
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス(ICPP12)
- Place of Presentation
  近畿大学（大阪府東大阪市）
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] CHARACTERIZATION OF ENZYMATIC ACTIVITY OF FCP/SCP TYPE SER/THR PHOSPHATASE FAMILY2016
- Author(s)
  Seiya Yagi, Takashi Yoneda, Kodai Otsubo, Kazuhiro Furukawa, and Yoshiro Chuman
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] プロテインホスファターゼの制御破綻による発がん機構と抗がん剤開発2016
- Author(s)
  中馬　吉郎
- Organizer
  第84回新潟大学理学部コロキウム
- Place of Presentation
  新潟大学（新潟県新潟市）
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 立体制約型libraryを用いた疾患関連タンパク質結合分子の同定2016
- Author(s)
  中馬　吉郎
- Organizer
  フォーラム「生命科学談話シリーズ」
- Place of Presentation
  九州大学博多駅オフィス(福岡県福岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 発癌関連ホスファターゼに対する新規基質同定法と阻害剤の開発2016
- Author(s)
  中馬吉郎
- Organizer
  第２２回ペプチドフォーラム
- Place of Presentation
  金沢大学サテライトプラザ（金沢市）
- Year and Date
  2016-03-05
- Invited
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] 発癌タンパク質PPM1Dを標的とする立体制約型DNA aptamerの同定2015
- Author(s)
  江口正敏、古川和広、中馬吉郎
- Organizer
  第5回グリーンケミストリー研究会
- Place of Presentation
  新潟大学(新潟市）
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] DEVELOPMENT OF THE NOVEL SUBSTRATE IDENTIFICATION METHODOLOGY FOR SER/THR PHOSPHATASES USING PHOSPHORYLATION MIMIC PHAGE DISPLAY LIBRARY2015
- Author(s)
  Kodai Otsubo, Kazuhiro Furukawa, Yoshiro Chuman
- Organizer
  第５２回ペプチド討論会
- Place of Presentation
  平塚中央貢民会（平塚市）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] Drosophilaモデル動物を用いた心臓形成におけるA-type laminの機能解析2015
- Author(s)
  小熊　義樹,打野　亮,中馬　吉郎, 杉山　伸,古川　和広
- Organizer
  第5回グリーンケミストリー研究会
- Place of Presentation
  新潟大学(新潟市）
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] リン酸化ミミック Phage Display法を用いたFCP1ホスファターゼの新規基質同定法の開発2015
- Author(s)
  大坪広大、古川和広、中馬吉郎
- Organizer
  第5回グリーンケミストリー研究会
- Place of Presentation
  新潟大学(新潟市）
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] In vivoにおけるlaminドメイン特異的なクロマチン相互作用および重合形成の解析2015
- Author(s)
  打野　亮, 杉山　伸, 中馬　吉郎, 古川　和広
- Organizer
  第5回グリーンケミストリー研究会
- Place of Presentation
  新潟大学(新潟市）
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] リン酸化ミミックファージディスプレイによるホスファターゼ基質同定法の開発2015
- Author(s)
  大坪広大, 古川和広, 中馬吉郎
- Organizer
  H27年度生化学会　関東支部会・第５６回新潟生化学懇話会
- Place of Presentation
  新潟日報メディアシップ（新潟市）
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-15K05560
[Presentation] Novel Fluorescent Probe TAP-4PH for Cytoplasmic Staining in Living Cell2014
- Author(s)
  F. Kudoh, F. Tano, A. Osawa, R. Kamada, Y. Chuman, K. Namba, K. Tanino, and K. Sakaguchi
- Organizer
  Frontiers in Chemical Sciences 2014 (SNU-HU)
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-11-28
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] ヒトPPM1Dホスファターゼによる染色体不安定化と新規発がん機構2014
- Author(s)
  中馬吉郎・藤田章弘、小笠原紗里、小境夕紀、梨本健紘、水上洋平、今川敏明、坂口和靖
- Organizer
  第55回新潟生化学懇話会
- Place of Presentation
  長岡技術科学大学(長岡市）
- Year and Date
  2014-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] p53誘導性ホスファターゼPPM1D過剰発現による染色体不安定性機構2013
- Author(s)
  中馬吉郎・藤田章弘、小笠原紗里、小境夕紀、梨本健紘、水上洋平、今川敏明、坂口和靖
- Organizer
  第86回日本生化学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] 17q23にコードされたPPM1Dホスファターゼ過剰発現による染色体不安定化2013
- Author(s)
  中馬吉郎・藤田章弘、小笠原紗里、小境夕紀、梨本健紘、水上洋平、今川敏明、坂口和靖
- Organizer
  第50回日本生化学会北海道支部会
- Place of Presentation
  北海道大学医学部フラテ会館
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] p53-inducible Protein phosphatase PPM1D -the oncogenic functions and development of PPM1D-specific inhibitors2013
- Author(s)
  Ｙoshiro Chuman
- Organizer
  The 2nd Taiwan-Japan Bilateral Conference on Protein Phosphatases
- Place of Presentation
  National Health Research Institutes Taiwan
- Invited
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Recognition of Phosphorylated Ser/Thr residues by Human PPM1 Family Phosphatases2013
- Author(s)
  Yoshiro Chuman, Yukiko Shirahata, Yuhei Kiyota, Ryo Iwamuro, Jose Isagani B. Janairo, Hiroaki Yagi, and Kazuyasu Sakaguchi
- Organizer
  10th International Conference on Protein Phosphatase
- Place of Presentation
  国立がんセンター（東京都）
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] p53誘導性ホスファターゼPPM1D研究の新展開2013
- Author(s)
  中馬　吉郎
- Organizer
  生物化学研究会2013
- Place of Presentation
  北海道大学
- Invited
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] ヒトPPM1ホスファターゼにおけるリン酸化アミノ酸選択性2012
- Author(s)
  中馬吉郎・岩室良・白幡祐貴子・Jose Isagani B. Janairo・清田雄平・八木寛陽・坂口和靖
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Suppression of Breast Cancer Cells Proliferation by a Small Molecule Inhibitor of p53-inducible Protein Phosphatase PPM1D2012
- Author(s)
  Y.Chuman
- Organizer
  第5回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  大阪大学(吹田市)
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] Expression of p53-inducible Protein phosphatase PPM1D in Pluripotent Human Germ Cell Tumor-derived Cell Line, NCCIT2012
- Author(s)
  Yoshiro Chuman, Takahiro Michiba, Kazuyasu Sakaguchi
- Organizer
  The 58th/60th NIBB Conference “Germline -Specification, Sex, and Stem Cells-“
- Place of Presentation
  岡崎カンファレンスセンター（愛知県）
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Ser/Thr specificity and metal prefeceince in human PPM1 family phosphatases2012
- Author(s)
  中馬吉郎・岩室良・白幡祐貴子・Jose Isagani B. Janairo・清田雄平・八木寛陽・坂口和靖
- Organizer
  第４９回ペプチド討論会
- Place of Presentation
  かごしま県民交流センター（鹿児島市）
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Suppression of Breast Cancer Cells Proliferation by Novel Inhibitor for p53-Inducible Protein Phosphatase PPM1D2011
- Author(s)
  Chuman Y.
- Organizer
  1st International Symposium on Carcinogenic Spiral & 9th International Conference on Protein Phosphatase
- Place of Presentation
  Tetsumon Memorial Hall, The University of Tokyo
- Year and Date
  2011-02-01
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] p53誘導性ホスファターゼのスプライシングバリアントの同定と阻害剤開発2010
- Author(s)
  中馬吉郎
- Organizer
  第47回日本生化学会北海道支部例会(招待講演)
- Place of Presentation
  北海道大学医学部第3講堂
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] p53誘導性ホスファターゼ特異的阻害剤の開発と細胞増殖抑制能2010
- Author(s)
  中馬吉郎
- Organizer
  日本化学会北海道支部2010年夏季研究発表会
- Place of Presentation
  函館高専
- Year and Date
  2010-07-24
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] Suppression of Breast Cancer Cells Proliferation by Novel Inhibitor for p53-Inducible Protein Phosphatase PPM1D2010
- Author(s)
  Y.Chuman
- Organizer
  第9回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東京大学鉄門記念講堂
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] p53誘導性ホスファターゼPPMID阻害による乳がん細胞増殖抑制作用2010
- Author(s)
  中馬吉郎
- Organizer
  BMB2010第83回日本生化学会、第33回日本分子生物学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] p53誘導性ホスファターゼPPM1D阻害による乳がん細胞増殖抑制機能2010
- Author(s)
  Y.Chuman
- Organizer
  BMB2010(第33回日本分子生物学会年会兼第83回日本生化学会大会合同大会)
- Place of Presentation
  ポートアイランド
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] p53誘導性ホスファターゼのスプライシングバリアントの同定と阻害剤開発2010
- Author(s)
  中馬吉郎
- Organizer
  第47回日本生化学会北海道支部例会
- Place of Presentation
  北海道大学医学部第3講堂(招待講演)
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] PPMID430, a Nove1 Alternative Splicing Variant of the Human PPM1D, can Dephosphorylate p53 and Exhibits Specific Tissue Expression2010
- Author(s)
  中馬吉郎
- Organizer
  BMB2010第83回日本生化学会第33回日本分子生物学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D, can Dephosphorylate p53 and Exhibits Specific Tissue Experession2010
- Author(s)
  Y.Chuman
- Organizer
  BMB2010(第33回日本分子生物学会年会兼第83回日本生化学会大会合同大会)
- Place of Presentation
  ポートアイランド
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] p53誘導性ホスファターゼのスプライシングバリアントの同定と阻害剤開発2010
- Author(s)
  Y.Chuman
- Organizer
  第47回日本生化学会北海道支部例会
- Place of Presentation
  北海道大学医学部
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] p53誘導性ホスファターゼ特異的阻害剤の開発と細胞増殖抑制能2010
- Author(s)
  Y.Chuman
- Organizer
  日本化学会北海道支部2010年夏季研究発表会
- Place of Presentation
  函館工業高等専門学校
- Year and Date
  2010-07-24
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] p53誘導性ホスファターゼPPM1D阻害による乳がん細胞増殖抑制作用2010
- Author(s)
  中馬吉郎
- Organizer
  BMB2010第83回日本生化学会、第33回日本分子生物学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] p53誘導性ホスファターゼPPM1Dの細胞周期における新規制御機構の解明2010
- Author(s)
  Y.Chuman
- Organizer
  北大グローバルCOEプログラム若手研究者成果発表会
- Place of Presentation
  北大工学部
- Year and Date
  2010-02-24
- Data Source
  KAKENHI-PROJECT-21310133
[Presentation] PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D, can Dephosphorylate p53 and Exhibits Specific Tissue Expression2010
- Author(s)
  中馬吉郎
- Organizer
  BMB2010第83回日本生化学会、第33回日本分子生物学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] p53誘導性ホスファターゼPPM1Dに対する新規阻害剤の開発2009
- Author(s)
  中馬吉郎
- Organizer
  第4回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  熊本大学(熊本)
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] p53誘導性ホスファターゼPPMIDに対する新規阻害剤の開発2009
- Author(s)
  中馬吉郎
- Organizer
  第4回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  熊本大学(熊本)
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] 癌抑制タンパク質p53誘導性ホスファターゼのAlternative splicing variant2008
- Author(s)
  中馬吉郎
- Organizer
  日本分子生物学会第8回春季シンポジウム
- Place of Presentation
  京王プラザホテル(札幌)
- Year and Date
  2008-05-27
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] ターン部位にアゾベンゼンアミノ酸誘導体を導入したペプチドの光による構造制御2008
- Author(s)
  中馬吉郎, 他
- Organizer
  分子情報生命科学シンポジウム2008
- Place of Presentation
  札幌
- Year and Date
  2008-02-29
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] リン酸化と脱リン酸化によるタンパク質制御機構〜p53誘導性ホスファターゼPPM1Dを中心にして〜2008
- Author(s)
  中馬吉郎
- Organizer
  第41回若手ペプチド夏の勉強会
- Place of Presentation
  プライムイン城陽(京都・城陽市)
- Year and Date
  2008-08-05
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] An Alternative Splicing Variant of the PPM1 Protein Phosnhatase PPM1D2008
- Author(s)
  Chuman Y
- Organizer
  MPSA2008
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2008-08-26
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] ヒトPPMIDの選択的スプライシングバリアントPPMID4302008
- Author(s)
  中馬吉郎
- Organizer
  第45回ぺプチド討論会
- Place of Presentation
  タワーホール船堀(東京都江戸川区)
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] ヒトPPM1Dの選択的スプライシングバリアントPPM1D4302008
- Author(s)
  中馬吉郎
- Organizer
  第45回ペプチド討論会
- Place of Presentation
  タワーホール船堀(東京都江戸川区)
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] Aβアミロイドペプチドのアミノ酸付加による構造制御2008
- Author(s)
  中馬吉郎
- Organizer
  日本化学会第87春季年会
- Place of Presentation
  立教大学(東京・池袋)
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-17750148
[Presentation] ターン部位にアゾベンゼンアミノ酸誘導体を導入したペプチドの光による構造制御2008
- Author(s)
  中馬吉郎
- Organizer
  分子情報生命科学シンポジウム2008
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2008-02-29
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] リン酸化と脱リン酸化によるタンパク質制御機構～p53誘導性ホスファターゼPPMIDを中心にして～2008
- Author(s)
  中馬吉郎
- Organizer
  第41回若手ペプチド夏の勉強会
- Place of Presentation
  プライムイン城陽(京都・城陽市)
- Year and Date
  2008-08-05
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] 癌抑制タンパク質p53誘導性ホスファターゼのAlternative splicing varlant2008
- Author(s)
  中馬吉郎
- Organizer
  日本分子生物学会第8回春季シンポジウム
- Place of Presentation
  京王プラザホテル・札幌
- Data Source
  KAKENHI-PROJECT-18310140
[Presentation] 癌抑制タンパク質p53誘導性ホスファターゼのAlternativesplicing variant2008
- Author(s)
  中馬吉郎
- Organizer
  日本分子生物学会第8回春季シンポジゥム
- Place of Presentation
  京王プラザホテル(札幌)
- Year and Date
  2008-05-27
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] An Alternative Splicing Variant of the PPM1 Protein Phosphatase PPMID2008
- Author(s)
  Chuman Y.
- Organizer
  MPSA2008
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2008-08-26
- Data Source
  KAKENHI-PROJECT-20770095
[Presentation] Alternative Splicing Variants of p53-inducible Protein Phosphatase PPM1D2007
- Author(s)
  中馬吉郎
- Organizer
  BMB2007:第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜、他(神奈川県横浜市)
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-17750148
[Presentation] Identification of Alternative Splicing Variants of PPM1 Protein Phospha tase PPM1D2007
- Author(s)
  中馬吉郎
- Organizer
  4th International Peptide Symposium in conjunction with 7th Australian Peptide Conference and 2nd Asia-Pacific International Peptide Symposium
- Place of Presentation
  Cairns, Great Barrier Reef, Queensland, Australia
- Year and Date
  2007-10-21
- Data Source
  KAKENHI-PROJECT-17750148
[Presentation] PPM1Dホスファターゼ過剰発現による新規発癌機構
- Author(s)
  中馬　吉郎
- Organizer
  第46 回若手ペプチド夏の勉強会
- Place of Presentation
  京都府立青少年海洋センター(京都府宮津市）
- Year and Date
  2014-08-03 – 2014-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] DNA高次構造体を介した多量体化バイオミネラリゼーションペプチドによる銀ナノ構造体形成
- Author(s)
  峯健太、坂口達也、佐々木慎一郎、中馬吉郎、鎌田瑠泉、坂口和靖
- Organizer
  化学系学協会北海道支部2015年冬季研究発表会
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2015-01-27 – 2015-01-28
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] 複眼形成におけるDrosophila A , B-type laminの機能解析
- Author(s)
  田英恵, 打野亮, 中馬吉郎,　杉山伸, 古川和広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] In vivoにおけるlaminドメイン特異的なクロマチン相互作用および重合形成の解析
- Author(s)
  打野　亮, 杉山　伸, 中馬　吉郎, 古川　和広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] ショウジョウバエを用いたプレニル化によるlaminの動態解析
- Author(s)
  二木瞭, 打野亮, 山本洋敬,角山貴昭, 中馬吉郎, 杉山伸, 古川和広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Development of small molecule PPM1D phosphatase inhibitors
- Author(s)
  Sari Ogasawara, Yuhei Kiyota, Yoshiro Chuman, Fumihiko Yoshimura, Keiji Tanino, Kazuyasu Sakaguchi
- Organizer
  第11回プロテインホスファターゼ国際学会
- Place of Presentation
  東北大学(仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Effects of Oligomerization and Orientation of Biomineralization Peptides on Formation and Structure of Silver Nanoparticles
- Author(s)
  T. Sakaguchi, J. I. B. Janairo, Y. Chuman, and K. Sakaguchi
- Organizer
  Frontier Chemistry Center the 3rd International Symposium
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Analysis of Active Sites in Human PPM1 Phosphatase Family
- Author(s)
  Yuhei Kiyota, Sari Ogasawara, Yukiko Shirahata, Yutaka Matsuyama, Yuichi Nishimura, Yoshiro Chuman Yasuyuki Shimohigashi and Kazuyasu Sakaguchi
- Organizer
  第11回プロテインホスファターゼ国際学会
- Place of Presentation
  東北大学(仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] PPM1Dホスファターゼ過剰発現による染色体不安定化機構
- Author(s)
  中馬吉郎・藤田章弘、小笠原紗里、小境夕紀、水上洋平、今川敏明、坂口和靖
- Organizer
  第４９回ペプチド討論会
- Place of Presentation
  徳島大学大塚講堂(徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] DNA高次構造体を介した多量体化バイオミネラリゼーションペプチドによる銀ナノ構造体形成
- Author(s)
  峯健太、坂口達也、佐々木慎一郎、中馬吉郎、鎌田瑠依、坂口和靖
- Organizer
  日本化学会北海道支部2015年冬季研究発表会
- Place of Presentation
  北海道大学(札幌市）
- Year and Date
  2015-01-27 – 2015-01-28
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] Drosophilaモデル動物を用いた心臓形成におけるA-type laminの機能解析
- Author(s)
  小熊義樹, 打野　亮　中馬吉郎, 杉山伸, 古川和広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24570146
[Presentation] 生細胞蛍光イメージングのための新規細胞質特異的プローブ
- Author(s)
  鎌田瑠泉、田野史、大澤歩、工藤風樹、中馬吉郎、難波康祐、谷野圭持、坂口和靖
- Organizer
  日本化学会第95春季年会（2015）
- Place of Presentation
  日本大学（船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24310152
[Presentation] Induction of genome instability by overexpression of PPM1D phosphatase in cancer cells
- Author(s)
  Yoshiro Chuman, Sari Ogasawara, Akihiro Fujita, Yuuki Kozakai, and Kazuyasu Sakaguchi
- Organizer
  第11回プロテインホスファターゼ国際学会
- Place of Presentation
  東北大学(仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-24570146

1. SAKAGUCHI Kazuyasu (00315053)

# of Collaborated Projects: 6 results

# of Collaborated Products: 39 results
2. Terao Yutaka (50397717)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. TOSHIAKI Imagawa (20142177)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
4. Higashimoto Yuichiro (40352124)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 土門久哲 (00594350)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 前川知樹 (50625168)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. SHIMOHIGASHI Yasuyuki (00211293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 嘉屋俊二 (90186023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 米澤大輔 (90711896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 阿部貴志 (30390628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 伊東孝祐 (20502397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 牛田晃臣 (10582976)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 村松正吾 (30295472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 梨本正之 (30228069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 八木寛陽

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Chuman Yoshiro 中馬 吉郎

CHUMAN Yoshiro 中馬 吉郎

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Functional optimization and establishment of comprehensive evaluation of membrane-permeable aptamers for drug development using AI technologyPrincipal Investigator

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Development of Next-Generation Platform for Light-induced DrugsPrincipal Investigator

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Elucidation of the mechanism for auto-penetrating DNA aptamers and their application as post-antibody drugsPrincipal Investigator

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Substrate identification method for protein phosphatases through the induction of enzyme-substrate intermediatePrincipal Investigator

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Study on the molecular mechanism of genome instability in the cells with overexpression of PPM1DPrincipal Investigator

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Analysis of splicing variant of p53-inducible phosphatase PPM1D on carcinogenesisPrincipal Investigator

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p53誘導性ホスファターゼPPM1Dの機能解析用分子ツールとしての阻害剤開発Principal Investigator

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Chuman Yoshiro 中馬吉郎

CHUMAN Yoshiro 中馬吉郎