Yokoe Shunichi 横江俊一

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YOKOE Syunichi 横江俊一

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Researcher Number	40454756
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 大阪医科薬科大学, 医学部, 助教 2017 – 2020: 大阪医科大学, 医学部, 助教 2009 – 2010: 大阪医科大学, 医学部, 助教 2007 – 2008: Hyogo College of Medicine, Faculty of Medicine, Instructor
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / General pharmacology Except Principal Investigator Pathological medical chemistry / Basic Section 56060:Ophthalmology-related / Basic Section 59010:Rehabilitation science-related / Nerve anatomy/Neuropathology
Keywords	Principal Investigator 心不全 / ホスホランバン / ユビキチンリガーゼ / SARAF / ユビキチン / Parkin / ユビキチンリガーぜ / 血液 / 心血管 Except Principal Investigator Cu … More / Zn-SOD / スーパーオキシドジスムターゼ / 黄斑浮腫 / SOCE活性 / 糖尿病網膜症 / SOCE / STIM1遺伝子 / 急性心筋梗塞　慢性心不全 / 心リハ / AMPK / STIM1 / 骨格筋 / トレッドミル運動 / 心臓リハビリ / 心不全 / Cu, Zn-SOD / cleavage of oligosaccharides / LEC rat / sugar chain / reactive oxygen species / SOD / プロテオグリカン / ヒアルロン酸 / 銅イオン / トランスフェリン / 活性酸素 / グリコサミノグリカン / 糖鎖 / Cys111 / Cu,Zn-SOD / LECラット / 家族性筋萎縮性側策硬化症 / 活性酸素種 / Zn-SODノックアウトマウス / スーパーオキドジスムターゼ / 鉄 / 過酸化脂質 / ヒドロキシノネナール / Cu/Zn-SODノックアウトマウス / 酸化ストレス / グルタチオンSトランスフェラーゼ / 腎臓 / SOD1ノックアウトマウス / SOD1 / チャージアイソマー / 構造変化 / 酸化 / ALS / 筋萎縮性側索硬化症 / MALDI-TOF-MS / 酸化的翻訳後修飾 / 筋萎縮性側索硬化症(ALS) / 抗体 Less

SUMO修飾によるSOCE制御因子SARAFおよび心不全制御機構の解明Principal Investigator
- Principal Investigator
  
  横江俊一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
O-GlcNAc修飾によるSOCE活性を応用した糖尿病網膜症・黄斑症の新規治療戦略
- Principal Investigator
  
  喜田照代
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
心不全の進行におけるSOCE制御因子SARAFとその安定化分子ALG-2の関与Principal Investigator
- Principal Investigator
  
  横江俊一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
STIM1に着目した心リハ効果の分子機構の解明と相乗効果が期待できる薬物の探索
- Principal Investigator
  
  永塚健宏
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Elucidation of the mechanism of PLN degradation by ParkinPrincipal Investigator
- Principal Investigator
  
  Shunichi Yokoe
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Identification and functional analysis of ubiquitin ligases that interact with PLN.Principal Investigator
- Principal Investigator
  
  Yokoe Shunichi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College
The compensatory mechanism against oxidative stress in kidney dysfunction
- Principal Investigator
  
  SUZUKI Keiichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hyogo College of Medicine
The role of oxidized SOD1 on ALS using the new antibody against oxidized SOD1 (anti-C111ox-SOD1)
- Principal Investigator
  
  FUJIWARA Noriko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Hyogo College of Medicine
Nuclear translocation of antioxidant enzymes and ROS metabolism
- Principal Investigator
  
  SUZUKI Keiichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hyogo College of Medicine

All 2022 2020 2018 2017 2009 2008

All Journal Article Presentation

[Journal Article] Phospholamban Is Downregulated by pVHL-Mediated Degradation through Oxidative Stress in Failing Heart.2017
- Author(s)
  Shunichi Yokoe, Michio Asahi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Issue: 11 Pages: 2232-2232
- DOI
  10.3390/ijms18112232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15583
[Journal Article] Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice2009
- Author(s)
  Yoshihara D., Fujiwara N., Ookawara T., Kato S., Sakiyama H., Yokoe S., Eguchi H., Suzuki K.
- Journal Title
  
  Free Radic. Biol. Med. 47
  
  Pages: 559-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590320
[Journal Article] Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice2009
- Author(s)
  Yoshihara D., Fujiwara N., Ookawara T., Kato S., Sakiyama H., Yokoe S., Eguchi H., Suzuki K
- Journal Title
  
  Free Radic. Biol. Med 47
  
  Pages: 559-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] 不全心において、ホスホランバンはParkinによるユビキチン修飾により分解されている2022
- Author(s)
  横江俊一、朝日通雄
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07130
[Presentation] 心不全病態のERストレス環境下で、SARAFとALG-2は分解されている2022
- Author(s)
  横江俊一
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06640
[Presentation] 心不全において、ホスホランバンはParkinによる分解を受けている2020
- Author(s)
  横江俊一、朝日通雄
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07130
[Presentation] Phospholamban is degraded by VHL E3 ubiquitin ligase in failing hearts2018
- Author(s)
  横江俊一
- Organizer
  WCP2018
- Data Source
  KAKENHI-PROJECT-17K15583
[Presentation] Phospholamban is degraded by VHL E3 ubiquitin ligase in failing hearts.2018
- Author(s)
  横江俊一、中川孝俊、朝日通雄
- Organizer
  WCP2018 KYOTO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15583
[Presentation] 心筋収縮調節因子ホスホランバンは、pVHLにより分解の制御を受けている2017
- Author(s)
  横江俊一
- Organizer
  第 38回日本循環制御医学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K15583
[Presentation] 心機能調節因子ホスホランバンの E3ユビキチンリガーゼによる制御機構の解析2017
- Author(s)
  横江俊一
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-17K15583
[Presentation] SOD1ノックアウトマウスにおけるGSTA4の誘導と生理的意義2008
- Author(s)
  吉原大作、藤原範子、大河原知水、崎山晴彦、横江俊一、江口裕伸、鈴木敬一郎
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)(p14)
- Place of Presentation
  神戸(Late-Breaking Abstracts)
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] ヒトCu/Zn-スーパーオキシドジスムターゼ(SOD1)のCys111の酸化と酸化型SOD1特異抗体の作製2008
- Author(s)
  藤原範子、中の三弥子、大河原知水、吉原大作、横江俊一、加藤信介、谷口直之、鈴木敬一郎
- Organizer
  第61回日本酸化ストレス学会学術集会(p66)
- Place of Presentation
  京都(抄録)
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] ヒトCu/Zn-スーパーオキシドジスムターゼ(SOD1)のCys111の酸化と酸化型SOD1特異抗体の作製2008
- Author(s)
  藤原範子、中の三弥子、大河原知水、吉原大作、横江俊一、加藤信介、谷口直之、鈴木敬一郎
- Organizer
  第61回日本酸化ストレス学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19500313
[Presentation] Cu/Zn-SODノックアウトマウスにおけるGSTA4の生理的意義2008
- Author(s)
  吉原大作、藤原範子、大河原知水、横江俊一、崎山晴彦、鈴木敬一郎
- Organizer
  第61回日本酸化ストレス学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590320
[Presentation] GSTA4-4 as a biomarker of oxidative stress in renal tubular cells2008
- Author(s)
  Yoshihara D., Fujiwara N., Ookawara T., Yokoe S., Suzuki K.
- Organizer
  BOSHD2008 Biomarkers of Oxidative Stress in Health and Diseases
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-20590320

1. FUJIWARA Noriko (10368532)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. SUZUKI Keiichiro (70221322)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. OOKAWARA Tomomi (50330452)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. 朝日通雄 (10397614)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. SAKIYAMA Haruhiko (30508958)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. EGUCHI Hironobu (60351798)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. YOSHIHARA Daisaku (00567266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 永塚健宏 (10860083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 喜田照代 (90610105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TOMODA kiichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. II masaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yokoe Shunichi 横江 俊一

YOKOE Syunichi 横江 俊一

Research Projects

Research Products

Co-Researchers

SUMO修飾によるSOCE制御因子SARAFおよび心不全制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

O-GlcNAc修飾によるSOCE活性を応用した糖尿病網膜症・黄斑症の新規治療戦略

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

心不全の進行におけるSOCE制御因子SARAFとその安定化分子ALG-2の関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

STIM1に着目した心リハ効果の分子機構の解明と相乗効果が期待できる薬物の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of PLN degradation by ParkinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and functional analysis of ubiquitin ligases that interact with PLN.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The compensatory mechanism against oxidative stress in kidney dysfunction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of oxidized SOD1 on ALS using the new antibody against oxidized SOD1 (anti-C111ox-SOD1)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nuclear translocation of antioxidant enzymes and ROS metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Phospholamban Is Downregulated by pVHL-Mediated Degradation through Oxidative Stress in Failing Heart.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice2009

Author(s)

Journal Title

Data Source

[Journal Article] Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice2009

Author(s)

Journal Title

Data Source

[Presentation] 不全心において、ホスホランバンはParkinによるユビキチン修飾により分解されている2022

Author(s)

Organizer

Data Source

[Presentation] 心不全病態のERストレス環境下で、SARAFとALG-2は分解されている2022

Author(s)

Organizer

Data Source

Yokoe Shunichi 横江俊一

YOKOE Syunichi 横江俊一