OKUI Tatsuo 奥井達雄

… Alternative Names

Okui Tatsuo 奥井達雄

奥井達雄オクイタツオ

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Researcher Number	40610928
Other IDs	https://orcid.org/0000-0002-7640-3274
Affiliation (Current)	2025: 鹿児島大学, 医歯学域歯学系, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 鹿児島大学, 医歯学域歯学系, 教授 2020 – 2023: 島根大学, 学術研究院医学・看護学系, 准教授 2020: 岡山大学, 大学病院, 医員 2016 – 2020: 岡山大学, 大学病院, 助教 2017: 岡山大学, 大学病院, 医員 … More 2014: 岡山大学, 大学病院, その他 2012: 岡山大学, 岡山大学病院, 医員 2011 – 2012: 岡山大学, 大学病院, 医員 Less
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Basic Section 57020:Oral pathobiological science-related
Keywords	Principal Investigator 知覚神経 / 骨痛 / 口腔癌 / 癌性疼痛 / 骨破壊 / 顎骨 / がん骨破壊病変 / 骨代謝 / 癌骨破壊 / 破骨細胞 … More / がん性疼痛 / HMGB1 / 歯学 / 骨転移 / 癌 / 癌骨転移 / 癌性骨痛 / 癌血管新生 / 血管新生 / mTOR / HSP90 … More Except Principal Investigator 口腔癌 / 破骨細胞 / 骨破壊 / 血管新生 / 骨転移 / Hedgehog / 癌骨破壊 / 顎骨破壊 / 癌 / 癌性骨疼痛 / 癌骨微小環境 / 癌性骨痛 / 癌関連線維芽細胞 / angiogenin / Bone Metabolism Tracing / 口腔がん / 癌の骨転移 / Lysyl oxidase / 癌の骨浸潤 / 高カルシウム血症 / 銅キレート / 乳酸 / がん / GPR81 / 乳酸シャトル / A375細胞 / plexin-B2 / ヘッジホッグ / 神経ペプチドCGRP / 口腔癌の骨浸潤・骨転移 / CGRP8-37 / CGRP / ケミカルメディエータ－ / 骨吸収機構 / 骨破壊病変 / ケミカルメディエーター / 骨浸潤 / 口腔扁平上皮癌 / 癌骨破壊病変 / マスト細胞 / Angiogenin / 分子標的治療 / 血管新生作用 / リボヌクレアーゼ / 抗腫瘍効果 / リボソームRNA / リボヌクレアーぜ / 新規口腔癌治療薬 / N65828 Less

Molecular Basis of Hedgehog Signaling and New Therapeutic Strategies for Cancer induced Bone-Destruction
- Principal Investigator
  
  志茂剛
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
口腔癌骨破壊病変における知覚神経と癌細胞の相互作用メカニズムの解明Principal Investigator
- Principal Investigator
  
  奥井達雄
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kagoshima University
  Shimane University
口腔癌におけるangiogeninレセプターplexin-B2の発現と機能解析
- Principal Investigator
  
  岸本晃治
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
The role of lactate shuttle inbone metastasis
- Principal Investigator
  
  Yoneda Toshiyuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Osaka University
Establishment of therapeutic strategies using copper chelates for bone destruction lesions of cancer and analysis of their functional mechanisms
- Principal Investigator
  
  Sasaki Akira
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
The role of neuropeptide CGRP and regulatory mechanism for bone destruction in bone invasion and bone metastasis of oral cancer
- Principal Investigator
  
  YOSHIOKA NORIE
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
HMGB1 induces bone pain associated with colonization of oral cancer in bonePrincipal Investigator
- Principal Investigator
  
  Okui Tatsuo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
The study of the regulatory mechanisms of cancer bone destruction metabolism and immunity in Hedgehog signaling
- Principal Investigator
  
  SHIMO Tsuyoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Development of molecular target therapy for oral cancer by an inhibitor of angiogenin activity, N65828
- Principal Investigator
  
  Kishimoto Koji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Okayama University
The relationship between cancer-associted fibroblast and mast cell on the osteolysis of cancer induced bone disease
- Principal Investigator
  
  Sasaki Akira
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Okayama University
Midkine promotes oral cancer bone pain and progressionPrincipal Investigator
- Principal Investigator
  
  Okui Tatsuo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Okayama University
Midkineを標的とした口腔扁平上皮癌に対する新規分子標的治療法の開拓Principal Investigator
- Principal Investigator
  
  奥井達雄
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Okayama University
The role of mTOR and HSP90 against oral cancer induced angiogenesisPrincipal Investigator
- Principal Investigator
  
  OKUI Tatsuo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Okayama University

All 2023 2022 2021 2020 2019 2018 2017 2016 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Cancer?nerve interplay in cancer progression and cancer-induced bone pain2023
- Author(s)
  Yoneda Toshiyuki、Hiasa Masahiro、Okui Tatsuo、Hata Kenji
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: オンライン版 Issue: 3 Pages: 415-427
- DOI
  10.1007/s00774-023-01401-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03859
[Journal Article] Mouse Models of Tumor Bone Metastasis and Invasion for Studying CCN Proteins.2023
- Author(s)
  Shimo T, Okui T, Horie N, Yokozeki K, Takigawa M, Sasaki A.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2582 Pages: 343-353
- DOI
  10.1007/978-1-0716-2744-0_24
- ISBN
  9781071627433, 9781071627440
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03817, KAKENHI-PROJECT-23K24551
[Journal Article] Lactate secreted via MCT4 from bone?colonizing breast cancer excites sensory neurons via GPR812023
- Author(s)
  Okui Tatsuo、Hiasa Masahiro、Hasegawa Kazuaki、Nakamura Tomoya、Ono Kisho、Ibaragi Soichiro、Kanno Takahiro、Sasaki Akira、Yoneda Toshiyuki
- Journal Title
  
  International Journal of Oncology
  
  Volume: 62 Issue: 3 Pages: 39-51
- DOI
  10.3892/ijo.2023.5487
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03859, KAKENHI-PROJECT-21K10071
[Journal Article] The Role of Hedgehog Signaling in the Melanoma Tumor Bone Microenvironment2023
- Author(s)
  Shamsoon Karnoon、Hiraki Daichi、Yoshida Koki、Takabatake Kiyofumi、Takebe Hiroaki、Yokozeki Kenji、Horie Naohiro、Fujita Naomasa、Nasrun Nisrina Ekayani、Okui Tatsuo、Nagatsuka Hitoshi、Abiko Yoshihiro、Hosoya Akihiro、Saito Takashi、Shimo Tsuyoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 10 Pages: 8862-8862
- DOI
  10.3390/ijms24108862
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10019, KAKENHI-PROJECT-22K10170, KAKENHI-PROJECT-23K20333, KAKENHI-PROJECT-23K24551
[Journal Article] The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer2022
- Author(s)
  Ishihara Shota、Hata Kenji、Hirose Katsutoshi、Okui Tatsuo、Toyosawa Satoru、Uzawa Narikazu、Nishimura Riko、Yoneda Toshiyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 6261-6274
- DOI
  10.1038/s41598-022-10143-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10071, KAKENHI-PROJECT-20H03859
[Journal Article] The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone2021
- Author(s)
  Okui Tatsuo、Hiasa Masahiro、Ryumon Shoji、Ono Kisho、Kunisada Yuki、Ibaragi Soichiro、Sasaki Akira、Roodman G. David、White Fletcher A.、Yoneda Toshiyuki
- Journal Title
  
  Journal of Bone Oncology
  
  Volume: 26 Pages: 100330-100330
- DOI
  10.1016/j.jbo.2020.100330
- NAID
  120007032763
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22719, KAKENHI-PROJECT-20H03859, KAKENHI-PROJECT-17H05104
[Journal Article] Expression of Neurokinin B Receptor in the Gingival Squamous Cell Carcinoma Bone Microenvironment2021
- Author(s)
  Shoko Yoshida, Tsuyoshi Shimo, Kiyofumi Takabatake, Yurika Murase, Kyoichi Obata, Tatsuo Okui, Yuki Kunisada, Soichiro Ibaragi, Hitoshi Nagatsuka, Akira Sasaki
- Journal Title
  
  Diagnostics (Basel, Switzerland)
  
  Volume: 11 Pages: 1044-1044
- NAID
  120007116755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02999
[Journal Article] Sensory nerves: A driver of the vicious cycle in bone metastasis?2021
- Author(s)
  Yoneda T、Hiasa M、Okui T、Hata K
- Journal Title
  
  Journal of Bone Oncology
  
  Volume: 30 Pages: 100387-100387
- DOI
  10.1016/j.jbo.2021.100387
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22719, KAKENHI-PROJECT-20H03859, KAKENHI-PROJECT-21K10071
[Journal Article] Expression and Role of IL-1β Signaling in Chondrocytes Associated with Retinoid Signaling during Fracture Healing2020
- Author(s)
  Shimo Tsuyoshi、Takebe Hiroaki、Okui Tatsuo、Kunisada Yuki、Ibaragi Soichiro、Obata Kyoichi、Kurio Naito、Shamsoon Karnoon、Fujii Saki、Hosoya Akihiro、Irie Kazuharu、Sasaki Akira、Iwamoto Masahiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 7 Pages: 2365-2365
- DOI
  10.3390/ijms21072365
- NAID
  120007127458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17090, KAKENHI-PROJECT-18K09641, KAKENHI-PROJECT-19K10171, KAKENHI-PROJECT-18H02999
[Journal Article] High mobility group box 1 induces bone pain associated with bone invasion in a mouse model of advanced head and neck cancer2020
- Author(s)
  Nakamura Tomoya、Okui Tatsuo、Hasegawa Kazuaki、Ryumon Shoji、Ibaragi Soichiro、Ono Kisho、Kunisada Yuki、Obata Kyoichi、Masui Masanori、Shimo Tsuyoshi、Sasaki Akira
- Journal Title
  
  Oncology Reports
  
  Volume: 44 Issue: 6 Pages: 2547-2558
- DOI
  10.3892/or.2020.7788
- NAID
  120007004824
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02999, KAKENHI-PROJECT-20H03889
[Journal Article] High-mobility group box 1 induces bone destruction associated with advanced oral squamous cancer via RAGE and TLR42020
- Author(s)
  Sakamoto Yumi、Okui Tatsuo、Yoneda Toshiyuki、Ryumon Shoji、Nakamura Tomoya、Kawai Hotaka、Kunisada Yuki、Ibaragi Soichiro、Masui Masanori、Ono Kisho、Obata Kyoichi、Shimo Tsuyoshi、Sasaki Akira
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 531 Issue: 3 Pages: 422-430
- DOI
  10.1016/j.bbrc.2020.07.120
- NAID
  120006890006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17224, KAKENHI-PROJECT-18H02999, KAKENHI-PROJECT-20H03859, KAKENHI-PROJECT-20H03889
[Journal Article] Retinoic Receptor Signaling Regulates Hypertrophic Chondrocyte-specific Gene Expression2019
- Author(s)
  SHIMO TSUYOSHI、KOYAMA EIKI、OKUI TATSUO、MASUI MASANORI、KUNISADA YUKI、IBARAGI SOICHIRO、YOSHIOKA NORIE、KURIO NAITO、YOSHIDA SHOKO、SASAKI AKIRA、IWAMOTO MASAHIRO
- Journal Title
  
  In Vivo
  
  Volume: 33 Issue: 1 Pages: 85-91
- DOI
  10.21873/invivo.11443
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02999
[Journal Article] Ammonium trtrathiomolybdate enhances the anti tumor effect of cisplatin via the suppression of ATPase copper transporting beta in head and neck squamous cell carcinoma2019
- Author(s)
  Ryumon S., Okui T.,Kunisada Y., Kishimoto K., Shimo T., Hasegawa K., Ibaragi S., Akiyama K., Thi Thu Ha N., Hassan NMM., Sasaki A.
- Journal Title
  
  Oncology Reports
  
  Volume: 42 Pages: 2611-2621
- DOI
  10.3892/or.2019.7367
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04405, KAKENHI-PROJECT-18H02999
[Journal Article] The Prognostic Implications of Bone Invasion in Gingival Squamous Cell Carcinoma2018
- Author(s)
  Shoko Yoshida, Tsuyoshi Shimo, Yurika Murase, KiyoFumi Takabatake, Koji Kishimoto, Soichiro Ibaragi, Norie Yoshioka, Tatsuo Okui, Hitoshi Nagatsuka AND Akira Sasaki
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 2 Pages: 955-962
- DOI
  10.21873/anticanres.12309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K20579, KAKENHI-PROJECT-16H06992, KAKENHI-PROJECT-16K20577
[Journal Article] Ammonium tetrathiomolybdate enhances the antitumor effects of cetuximab via the suppression of osteoclastogenesis in head and neck squamous carcinoma.2018
- Author(s)
  Morisawa A, Okui T, Shimo T, Ibaragi S, Okusha Y, Ono M, Nguyen TTH, Hassan NMM, Sasaki A.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 52 Pages: 989-999
- DOI
  10.3892/ijo.2018.4242
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17895, KAKENHI-PROJECT-16H05524, KAKENHI-PROJECT-16H06992, KAKENHI-PROJECT-16K15802
[Journal Article] Lactate Transporter Monocarboxylate Transporter 4 Induces Bone Pain in Head and Neck Squamous Cell Carcinoma.2018
- Author(s)
  Hasegawa K, Okui T, Shimo T, Ibaragi S, Kawai H, Ryumon S, Kishimoto K, Okusha Y, Monsur Hassan NM, Sasaki A.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Issue: 11 Pages: 3317-3317
- DOI
  10.3390/ijms19113317
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17895, KAKENHI-PROJECT-18K17224, KAKENHI-PROJECT-18K17225
[Journal Article] Low-intensity pulsed ultrasound stimulation promotes osteoblast differentiation through hedgehog signaling2018
- Author(s)
  Matsumoto Kenichi、Shimo Tsuyoshi、Kurio Naito、Okui Tatsuo、Ibaragi Soichiro、Kunisada Yuki、Obata Kyoichi、Masui Masanori、Pai Pang、Horikiri Yuu、Yamanaka Nobuyuki、Takigawa Masaharu、Sasaki Akira
- Journal Title
  
  J. Cell Biochem.
  
  Volume: 印刷中 Issue: 6 Pages: 4352-4360
- DOI
  10.1002/jcb.26418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05014, KAKENHI-PROJECT-16H06992
[Journal Article] Oral Squamous Cell Carcinoma-derived Sonic Hedgehog Promotes Angiogenesis2017
- Author(s)
  Kuroda H, Kurio N, Shimo T, Matsumoto K, Masui M, Takabatake K, Okui T, Ibaragi S, Kunisada Y, Obata K, Yoshioka N, Kishimoto K, Nagatsuka H, Sasaki A.
- Journal Title
  
  Anticancer Research
  
  Volume: 37 Issue: 12 Pages: 6731-6737
- DOI
  10.21873/anticanres.12132
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20577, KAKENHI-PROJECT-16H06992
[Journal Article] Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3.2017
- Author(s)
  Hiasa M, Okui T, Allette YM, Ripsch MS, Sun-Wada GH, Wakabayashi H, Roodman GD, White FA, Yoneda T
- Journal Title
  
  Cancer Research
  
  Volume: 77(6) Issue: 6 Pages: 1283-1295
- DOI
  10.1158/0008-5472.can-15-3545
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06992, KAKENHI-PROJECT-16H07018, KAKENHI-PROJECT-26293394, KAKENHI-PROJECT-17H04377
[Journal Article] Role of Neurokinin 3 Receptor Signaling in Oral Squamous Cell Carcinoma.2017
- Author(s)
  Obata K, Shimo T, Okui T, Matsumoto K, Takada H, Takabatake K, Kunisada Y, Ibaragi S, Yoshioka N, Kishimoto K, Nagatsuka H, Sasaki A.
- Journal Title
  
  Anticancer Research
  
  Volume: 37 Issue: 11 Pages: 6119-6123
- DOI
  10.21873/anticanres.12060
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20577, KAKENHI-PROJECT-16H06992
[Journal Article] Semaphorin 4D promotes bone invasion in head and neck squamous cell carcinoma.2017
- Author(s)
  Takada H, Ibaragi S, Eguchi T, Okui T, Obata K, Masui M, Morisawa A, Takabatake K, Kawai H, Yoshioka N, Hassan NMM, Shimo T, Hu GF, Nagatsuka H, Sasaki A.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 51 Issue: 2 Pages: 625-32
- DOI
  10.3892/ijo.2017.4050
- NAID
  120006370695
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11642, KAKENHI-PROJECT-17K11836, KAKENHI-PROJECT-16K20577, KAKENHI-PROJECT-16H06992
[Journal Article] Tachykinin Receptor 3 Distribution in Human Oral Squamous Cell Carcinoma.2016
- Author(s)
  Obata K1, Shimo T, Okui T, Matsumoto K, Takada H, Takabatake K, Kunisada Y, Ibaragi S, Nagatsuka H, Sasaki A.
- Journal Title
  
  Anti cancer research
  
  Volume: 36(12) Issue: 12 Pages: 6335-6341
- DOI
  10.21873/anticanres.11230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06992, KAKENHI-PROJECT-16K20577
[Journal Article] Novel HSP90 inhibitor NVP-AUY922 enhances the anti-tumor effect of temsirolimus against oral squamous cell carcinoma2013
- Author(s)
  Okui T, Shimo T, Fukazawa T, Mohammad Monsur Hassan N, Honami T, Ibaragi S, Takaoka M, Naomoto Y, Sasaki A
- Journal Title
  
  Curr Cancer Drug Targets
  
  Volume: 13(3) Pages: 289-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890124
[Journal Article] Novel HSP90 Inhibitor NVP-AUY922 Enhances the Anti-tumor Effect of Temsirolimus Against Oral Squamous Cell Carcinoma.2013
- Author(s)
  (Okui T), Shimo T, Fukazawa T, Mohammad Monsur Hassan N, Honami T, Ibaragi S, Takaoka M, Naomoto Y, Sasaki A.
- Journal Title
  
  Current cancer drug targets
  
  Volume: 13 Pages: 289-299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890124
[Journal Article] Sonic hedgehog signaling promotes growth of oral squamous cell carcinoma cells associated with bone destruction.2012
- Author(s)
  Honami T, Shimo T, Okui T, Kurio N, Hassan NM, Iwamoto M, Sasaki A
- Journal Title
  
  Oral Oncol
  
  Volume: 48(1) Issue: 1 Pages: 49-55
- DOI
  10.1016/j.oraloncology.2011.08.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890124
[Journal Article] Hypoxia-induced up-regulation of angiogenin, besides VEGF, is related to progression of oral cancer.2012
- Author(s)
  Kishimoto K, Yoshida S, Ibaragi S, Yoshioka N, Okui T, Hu GF, Sasaki A
- Journal Title
  
  Oral Oncol.
  
  Volume: 48(11) Issue: 11 Pages: 1120-7
- DOI
  10.1016/j.oraloncology.2012.05.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890124
[Journal Article] Anti-tumor effect of a novel FAK inhibitor TAE226 against human oral squamous cell carcinoma.2012
- Author(s)
  Kurio N, Shimo T, Fukazawa T, Okui T, Hassan NM, Honami T, Horikiri Y, Hatakeyama S, Takaoka M, Naomoto Y, Sasaki A.
- Journal Title
  
  Oral Oncol
  
  Volume: 48(11) Issue: 11 Pages: 1159-70
- DOI
  10.1016/j.oraloncology.2012.05.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890124
[Journal Article] Antitumor effect of novel HSP90 inhibitor NVP-AUY922 against oral squamous cell carcinoma2011
- Author(s)
  Okui T, Shimo T, Hassan NM, Fukazawa T, Kurio N, Takaoka M, Naomoto Y, Sasaki A
- Journal Title
  
  Anticancer Res
  
  Volume: 31(4) Pages: 1197-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890124
[Journal Article] Antitumor Effect of Novel HSP90 Inhibitor NVP-AUY922 against Oral Squamous Cell Carcinoma2011
- Author(s)
  Tatsuo okui, et al
- Journal Title
  
  Anti cancer research
  
  Volume: 31 Pages: 1197-1204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890124
[Presentation] 癌骨微量環境における神経ペプチドCGRPの役割に関する検討2019
- Author(s)
  坂本裕美，吉岡德枝，奥井達雄，竜門省二，伊原木聰一郎，佐々木　朗
- Organizer
  第64回（公社）日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-18K09811
[Presentation] Bone pain-modifying actions of osteocytes via connexin43-mediated communications with sensory nerves2017
- Author(s)
  Masahiro Hiasa, Tatsuo Okui, Jesu´ s Delgado-Calle, Teresita Bellido, G David Roodman, Fletcher White, Lilian Plotkin, Toshiyuki Yoneda
- Organizer
  44th European Calcified Tissue Society Congress
- Data Source
  KAKENHI-PROJECT-16H06992
[Presentation] TRPV1 を通じて興奮した知覚神経は HGF 産生により骨内でのがんの進展および骨からの二次転移を促進する2017
- Author(s)
  奥井達雄，日浅雅博，志茂剛，Fletcher A White，G. David Roodman，佐々木朗，米田俊之
- Organizer
  第61回（公社）日本口腔外科学会総会
- Data Source
  KAKENHI-PROJECT-16H06992
[Presentation] Neuronal HGF regulates breast cancer progression and bone pain induction2017
- Author(s)
  Tatsuo Okui, Masahiro Hiasa, Fletcher White, G David Roodman, Toshiyuki Yoneda.
- Organizer
  44th European Calcified Tissue Society Congress
- Data Source
  KAKENHI-PROJECT-16H06992
[Presentation] 新規HSP90阻害薬NVP-AUY922はTemsirolimusの抗腫瘍効果を増強する2011
- Author(s)
  奥井達雄
- Organizer
  第56回日本口腔外科学会総会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23890124
[Presentation] Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction
- Author(s)
  奥井達雄
- Organizer
  岡山歯学会総会
- Place of Presentation
  岡山
- Invited
- Data Source
  KAKENHI-PROJECT-23890124

1. Sasaki Akira (00170663)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. SHIMO Tsuyoshi (40362991)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
3. 伊原木聰一郎 (80549866)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. Kishimoto Koji (40243480)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. YOSHIOKA NORIE (50362984)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. Yoneda Toshiyuki (80142313)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 吉田祥子 (00616047)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. 長塚仁 (70237535)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 高畠清文 (70736537)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. 青山絵理子 (10432650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 國定勇希 (10779416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 滝川正春 (20112063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 久保田聡 (90221936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 波多賢二 (80444496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 増井正典 (80881143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 小野喜章 (30845384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 堀江尚弘 (30802318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 建部廣明 (40638293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 平木大地 (40877560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 谷村明彦 (70217149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 細矢明宏 (70350824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. HIASA Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. EGUCHI Takanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 河合穂高

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 村瀬友里香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 奥舎有加

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

OKUI Tatsuo 奥井 達雄

Okui Tatsuo 奥井 達雄

奥井 達雄 オクイ タツオ

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口腔癌骨破壊病変における知覚神経と癌細胞の相互作用メカニズムの解明Principal Investigator

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HMGB1 induces bone pain associated with colonization of oral cancer in bonePrincipal Investigator

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Midkine promotes oral cancer bone pain and progressionPrincipal Investigator

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Midkineを標的とした口腔扁平上皮癌に対する新規分子標的治療法の開拓Principal Investigator

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The role of mTOR and HSP90 against oral cancer induced angiogenesisPrincipal Investigator

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[Journal Article] Cancer?nerve interplay in cancer progression and cancer-induced bone pain2023

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OKUI Tatsuo 奥井達雄

Okui Tatsuo 奥井達雄

奥井達雄オクイタツオ