Uchino Haruto 内野晴登

Researcher Number	40775144
Other IDs
Affiliation (Current)	2025: 北海道大学, 大学病院, 特任助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 北海道大学, 大学病院, 特任助教 2021: 北海道大学, 医学研究院, 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related Except Principal Investigator Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator DNAメチル化 / もやもや病 Except Principal Investigator Moyamoya disease / microRNA / Epigenome / Pial synangiosis / 創始者変異 / RNF213 / エピゲノム / 血漿microRNA … More / 病態修飾因子 / 発症素因 / もやもや病 / pial synangiosis / angiogenesis / epigenome / blood biomarker / circulating microRNA Less

Epigenetic regulation analysis in angiogenesis/pial synangiosis on the meninges in Moyamoya disease
- Principal Investigator
  
  伊東雅基
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
もやもや病の末梢血細胞DNAメチル化解析による発病機序の解明Principal Investigator
- Principal Investigator
  
  内野晴登
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
Comprehensive validation of circulating microRNA signatures for Moyamoya disease early detection as an epigenome blood biomarker
- Principal Investigator
  
  Ito Masaki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation Book

[Book] Epigenetics Methods, Chapter 23: Detection and Quantification of MicroRNAs (miRNAs) and High Throughput miRNAs Profiling2020
- Author(s)
  Ito M, Uchino H
- Total Pages
  736
- Publisher
  Elsevier
- ISBN
  9780128194140
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Impact of intraoperative cortical indocyanine green extravasation on local vasogenic edema immediately after direct revascularization in an adult with moyamoya disease: illustrative case2024
- Author(s)
  YAMASAKI Maeho、ITO Masaki、UCHINO Haruto、SUGIYAMA Taku、FUJIMURA Miki
- Journal Title
  
  Journal of Neurosurgery: Case Lessons
  
  Volume: 7 Issue: 13
- DOI
  10.3171/case2465
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Efficacy of Mobile Telemedicine System for Digital Subtraction Angiography of Moyamoya Disease Compared with Picture Archiving and Communication System2024
- Author(s)
  OSANAI Toshiya, UCHINO Haruto, ITO Masaki, FUJIMURA Miki
- Journal Title
  
  JMA Journal
  
  Volume: 7 Issue: 2 Pages: 282-285
- DOI
  10.31662/jmaj.2023-0129
- ISSN
  2433-328X, 2433-3298
- Year and Date
  2024-04-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Long-term Outcomes of Combined Revascularization Surgery for Moyamoya Disease in the Elderly: A Single Institute Experience2024
- Author(s)
  KURISU Kota、ITO Masaki、UCHINO Haruto、SUGIYAMA Taku、FUJIMURA Miki
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 64 Issue: 3 Pages: 108-115
- DOI
  10.2176/jns-nmc.2023-0219
- ISSN
  0470-8105, 1349-8029
- Year and Date
  2024-03-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Predictive value of the hemispheric magnetic resonance angiography score on the development of indirect pial synangiosis after combined revascularization surgery for adult moyamoya disease2024
- Author(s)
  UCHINO Haruto, ITO Masaki, FUJIMA Noriyuki, TOKAIRIN Kikutaro, TATEZAWA Ryota, SUGIYAMA Taku, FUJIMURA Miki
- Journal Title
  
  Acta Neurochir (Wien)
  
  Volume: 166(1) Pages: 181-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Moyamoya Syndrome Associated with Late-onset Idiopathic Aqueduct Stenosis Successfully Treated with Endoscopic Third Ventriculostomy2024
- Author(s)
  HONDA Taishi、ITO Masaki、UCHINO Haruto、SUGIYAMA Taku、FUJIMURA Miki
- Journal Title
  
  NMC Case Report Journal
  
  Volume: 11 Issue: 0 Pages: 13-18
- DOI
  10.2176/jns-nmc.2023-0195
- ISSN
  2188-4226
- Year and Date
  2024-12-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Effective Smartphone Application Use for Postoperative Management of Moyamoya Disease2024
- Author(s)
  UCHINO Haruto, OSANAI Toshiya, ITO Masaki, KURISU Kota, SUGIYAMA Taku, FUJIMURA Miki
- Journal Title
  
  Neurol Med Chir (Tokyo)
  
  Volume: 64(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Association of RNF213 polymorphism and cortical hyperintensity sign on fluid-attenuated inversion recovery images after revascularization surgery for moyamoya disease: possible involvement of intrinsic vascular vulnerability2023
- Author(s)
  UCHINO Haruto、ITO Masaki、TOKAIRIN Kikutaro、TATEZAWA Ryota、SUGIYAMA Taku、KAZUMATA Ken、FUJIMURA Miki
- Journal Title
  
  Neurosurgical Review
  
  Volume: 46 Issue: 1 Pages: 119-119
- DOI
  10.1007/s10143-023-02030-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Chronological Volume Changes of the Temporal Muscle Pedicle Used for Encephalo-myo-synangiosis in Combined Revascularization for Moyamoya Disease: A Prospective Observational Study2023
- Author(s)
  MIZUSHIMA Makoto、ITO Masaki、FUJIMA Noriyuki、UCHINO Haruto、SUGIYAMA Taku、FUJIMURA Miki
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 63 Issue: 7 Pages: 304-312
- DOI
  10.2176/jns-nmc.2023-0008
- ISSN
  0470-8105, 1349-8029
- Year and Date
  2023-07-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Impact of RNF213 founder polymorphism (p.R4810K) on the postoperative development of indirect pial synangiosis after direct/indirect combined revascularization surgery for adult Moyamoya disease2022
- Author(s)
  Ito Masaki、Kawabori Masahito、Sugiyama Taku、Tokairin Kikutaro、Tatezawa Ryota、Uchino Haruto、Kazumata Ken、Houkin Kiyohiro、Fujimura Miki
- Journal Title
  
  Neurosurgical Review
  
  Volume: online ahead of print Issue: 3 Pages: 2305-2313
- DOI
  10.1007/s10143-022-01749-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765, KAKENHI-PROJECT-20K09362
[Journal Article] Crossed cerebellar diaschisis as an indicator of severe cerebral hyperperfusion after direct bypass for moyamoya disease2020
- Author(s)
  Uchino Haruto、Kazumata Ken、Ito Masaki、Nakayama Naoki、Kuroda Satoshi、Houkin Kiyohiro
- Journal Title
  
  Neurosurgical Review
  
  Volume: 44 Issue: 1 Pages: 599-605
- DOI
  10.1007/s10143-020-01265-8
- NAID
  120006958359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Optogenetic Stimulation Reduces Neuronal Nitric Oxide Synthase Expression After Stroke2020
- Author(s)
  Pendharkar Arjun V.、Smerin Daniel、Gonzalez Lorenzo、Wang Eric H.、Levy Sabrina、Wang Stephanie、Ishizaka Shunsuke、Ito Masaki、Uchino Haruto、Chiang Terrance、Cheng Michelle Y.、Steinberg Gary K.
- Journal Title
  
  Translational Stroke Research
  
  Volume: 12 Issue: 2 Pages: 347-356
- DOI
  10.1007/s12975-020-00831-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Association of cognitive function with cerebral blood flow in children with moyamoya disease2020
- Author(s)
  Kazumata Ken、Tokairin Kikutaro、Sugiyama Taku、Ito Masaki、Uchino Haruto、Osanai Toshiya、Kawabori Masahito、Nakayama Naoki、Houkin Kiyohiro
- Journal Title
  
  Journal of Neurosurgery: Pediatrics
  
  Volume: 25 Issue: 1 Pages: 62-68
- DOI
  10.3171/2019.7.peds19312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Brain Structure, Connectivity, and Cognitive Changes Following Revascularization Surgery in Adult Moyamoya Disease2019
- Author(s)
  Kazumata Ken、Tha Khin Khin、Tokairin Kikutaro、Ito Masaki、Uchino Haruto、Kawabori Masahito、Sugiyama Taku
- Journal Title
  
  Neurosurgery
  
  Volume: 85 Issue: 5 Pages: E943-E952
- DOI
  10.1093/neuros/nyz176
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] もやもや病のエピゲノム病態修飾因子＜血漿microRNA＞探索2024
- Author(s)
  伊東雅基、内野晴登、東海林菊太郎、杉山拓、川堀真人、岩田育子、矢部一郎、寳金清博、藤村幹
- Organizer
  第53回日本脳卒中の外科学会学術集会シンポジウム 02 (卒外SY02)
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] Incidence and characteristics of extremely advanced Moyamoya disease with Suzuki's angiographic stage 6: Single institute experience2023
- Author(s)
  ITO Masaki, UCHINO Haruto, FUJIMURA Miki
- Organizer
  International Symposium of Cerebral Blood Flow & Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] Incidence and characteristics of extremely advanced Moyamoya disease with Suzuki's angiographic stage 6: Single institute experience2023
- Author(s)
  ITO Masaki, UCHINO Haruto, FUJIMURA Miki
- Organizer
  The 16th Korea-Japan Joint Conference on Surgery for Cerebral Stroke
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] もやもや病複合血行再建術後の側頭筋腫脹をもたらす患者要因の探索2023
- Author(s)
  水嶋慎、伊東雅基、内野晴登、栗栖宏多、杉山拓、藤村幹
- Organizer
  第53回日本脳卒中の外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] RNF213創始者変異は成人もやもや病複合血行再建術後の間接バイパス路発達に寄与する2021
- Author(s)
  伊東雅基, 川堀真人, 杉山拓, 東海林菊太郎, 舘澤諒大, 内野晴登, 数又研, 寳金清博, 藤村幹
- Organizer
  第80回日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] 成人もやもや病複合血行再建術後バイパス路発達度におけるRNF213創始者変異の意義2021
- Author(s)
  伊東雅基、川堀真人、杉山拓、東海林菊太郎、舘澤諒大、内野晴登、数又研、寳金清博、藤村幹
- Organizer
  第39回 The Mt. Fuji workshop on CVD
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] RNF213創始者変異は成人もやもや病複合血行再建術後の間接バイパス路発達に寄与する2021
- Author(s)
  伊東雅基, 川堀真人, 杉山拓, 東海林菊太郎, 舘澤諒大, 内野晴登, 数又研, 寳金清博, 藤村幹
- Organizer
  第64回　日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] 成人もやもや病に対する間接バイパス術に残された課題ーRNF213創始者変異術前検討の意義2021
- Author(s)
  伊東雅基, 川堀真人, 杉山拓, 東海林菊太郎, 舘澤諒大, 内野晴登, 数又研, 寳金清博, 藤村幹
- Organizer
  第51回　日本脳卒中の外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03765

1. Ito Masaki (10399850)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
2. 藤村幹 (00361098)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. 東海林菊太郎 (70883164)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. 佐藤典宏 (50360912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 矢部一郎 (60372273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 杉山拓 (70748863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
7. 寳金清博 (90229146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 中山若樹 (40421961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 数又研 (60634144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
10. 浜内祝嗣 (70794387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Uchino Haruto 内野 晴登

Research Projects

Research Products

Co-Researchers

Epigenetic regulation analysis in angiogenesis/pial synangiosis on the meninges in Moyamoya disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

もやもや病の末梢血細胞DNAメチル化解析による発病機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive validation of circulating microRNA signatures for Moyamoya disease early detection as an epigenome blood biomarker

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] Epigenetics Methods, Chapter 23: Detection and Quantification of MicroRNAs (miRNAs) and High Throughput miRNAs Profiling2020

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Impact of intraoperative cortical indocyanine green extravasation on local vasogenic edema immediately after direct revascularization in an adult with moyamoya disease: illustrative case2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of Mobile Telemedicine System for Digital Subtraction Angiography of Moyamoya Disease Compared with Picture Archiving and Communication System2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Long-term Outcomes of Combined Revascularization Surgery for Moyamoya Disease in the Elderly: A Single Institute Experience2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Predictive value of the hemispheric magnetic resonance angiography score on the development of indirect pial synangiosis after combined revascularization surgery for adult moyamoya disease2024

Author(s)

Journal Title

Data Source

[Journal Article] Moyamoya Syndrome Associated with Late-onset Idiopathic Aqueduct Stenosis Successfully Treated with Endoscopic Third Ventriculostomy2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Effective Smartphone Application Use for Postoperative Management of Moyamoya Disease2024

Author(s)

Journal Title

Data Source

[Journal Article] Association of RNF213 polymorphism and cortical hyperintensity sign on fluid-attenuated inversion recovery images after revascularization surgery for moyamoya disease: possible involvement of intrinsic vascular vulnerability2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronological Volume Changes of the Temporal Muscle Pedicle Used for Encephalo-myo-synangiosis in Combined Revascularization for Moyamoya Disease: A Prospective Observational Study2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Impact of RNF213 founder polymorphism (p.R4810K) on the postoperative development of indirect pial synangiosis after direct/indirect combined revascularization surgery for adult Moyamoya disease2022

Author(s)

Uchino Haruto 内野晴登