Yabe Ichiro 矢部一郎

… Alternative Names

YABE Ichiro 矢部一郎

谷部一郎ヤベイチロウ

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Researcher Number	60372273
Other IDs
External Links
Affiliation (Current)	2025: 北海道大学, 医学研究院, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 北海道大学, 医学研究院, 教授 2017 – 2019: 北海道大学, 医学研究院, 准教授 2016: 北海道大学, 医学研究科, 准教授 2013 – 2014: 北海道大学, 大学院医学研究科, 准教授 2007 – 2011: Hokkaido University, Grad. School of Med., Associate Prof. … More 2006: 北海道大学, 大学院医学研究科, 助教授 2005: 北海道大学, 大学院・医学研究科, 講師 2004: Hokkaido Univ., Grad School of Med., Instructor, 大学院・医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Neurology / Basic Section 56060:Ophthalmology-related / Basic Section 58010:Medical management and medical sociology-related / Basic Section 52010:General internal medicine-related / Basic Section 53020:Cardiology-related / Basic Section 56010:Neurosurgery-related / Basic Section 90110:Biomedical engineering-related / Neurology / Neurophysiology and muscle physiology / Radiation science
Keywords	Principal Investigator タウオパチー / 脊髄小脳変性症 / Bassoon / 進行性核上性麻痺 / ^<31>P-MRS / PRKCG / ノックインマウス / 筋エネルギー代謝 / 多系統萎縮症 / モデル動物 … More / tauopathy / ubiquitin / Bassoon proteinopathy / パーキンソニズム / 認知症 / 神経変性 / バイオマーカー / 多発性硬化症 / BSN遺伝子変異 / BSN proteinopathy / パーキンソン症候群 / 脳・神経 / タウオパチィー / タウ / PET / 筋萎縮性側索硬化症 / SCA14 / POLG1 / ミトコンドリア / パーキンソン病 / POLG / Machado-Joseph disease / 運動失調 / CACNAIA / CACNA1A / 家族性片麻痺性片頭痛 / 31P-MRS / FMR1 / phospholipase Cβ4 / protein kinase C / spinocerebellar ataxia / protein kinase C gamma / 遺伝子 … More Except Principal Investigator 遺伝子 / 多系統萎縮症 / 脊髄小脳変性症 / 神経難病 / パーキンソン病 / 発症機序 / 素因遺伝子 / アクロレイン / 滲出型加齢黄斑変性 / αシヌクレイン / 網膜色素上皮細胞 / 網膜色素上皮 / LRRK2 / 加齢黄斑変性 / 均てん化 / 医療格差 / ICT / ゲノム医療 / 遠隔医療 / 骨量 / 骨格筋量 / 進行性核上性麻痺 / 骨粗鬆症 / サルコペニア / パーキンソニズム / バイオマーカー / 末梢血単核球 / ミトコンドリア / 筋ジストロフィー / 創始者変異 / RNF213 / エピゲノム / 血漿microRNA / 病態修飾因子 / 発症素因 / もやもや病 / pial synangiosis / angiogenesis / epigenome / blood biomarker / circulating microRNA / Moyamoya disease / 非侵襲的 / 化学交換緩和移動イメージング / 脳脊髄液 / 導電率 / 神経疾患 / ゲノム / susceptible genes / genes / multiple sclerosis / 疾患感受性 / 多発性硬化症 / neurodegenerative disorder / spinocerebellar ataxia / molecular mechanism / spinocerebellar degeneration / 分子生物学 / 心理物理検査 / 霊長類 / 高次脳機能 / 小脳 / 予測制御 / マカクサル / 半月小葉 / 課題開発 / 脳画像 / 高次機能 / MRI / 脳 / 頚髄 / 拡散テンソル / 神経変性疾患 / 脊髄小脳性症 / ゲノム構造多型 / コピー数多型 / 脳神経疾患 / 関連解析 Less

Identification of issues and solution strategies for the development of genomic medicine in remote areas lacking in medical resources
- Principal Investigator
  
  山田崇弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Hokkaido University
Mechanism analysis research of Bassoon proteinopathyPrincipal Investigator
- Principal Investigator
  
  矢部一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hokkaido University
Japanese prospective multicenter study on the prognostic influence of sarcopenia and osteoporosis in Parkinsonism
- Principal Investigator
  
  饗場郁子
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Higashinagoya National Hospital
末梢血単核球ミトコンドリア機能を筋ジストロフィーの重症度評価・治療に応用する。
- Principal Investigator
  
  山澤弘州
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hokkaido University
加齢黄斑変性におけるセリン/スレオニンキナーゼLRRK2の病態意義解明
- Principal Investigator
  
  野田航介
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Hokkaido University
Noninvasive analysis of the cerebrospinal fluid composition by MRI
- Principal Investigator
  
  THA KHIN KHIN
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Hokkaido University
Pathophysiological study of Bassoon proteinopathyPrincipal Investigator
- Principal Investigator
  
  Yabe Ichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hokkaido University
Comprehensive validation of circulating microRNA signatures for Moyamoya disease early detection as an epigenome blood biomarker
- Principal Investigator
  
  Ito Masaki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
Genetic analysis study of syringomyelia
- Principal Investigator
  
  Sasaki Hidenao
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
Pathomechanism study of progressive supranuclear palsy based on genetic analysis in familial progressive supranuclear palsyPrincipal Investigator
- Principal Investigator
  
  Yabe Ichiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
Development of behavioral paradigms to evaluate cerebellar cognitive functions
- Principal Investigator
  
  KURKIN SERGEY
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Hokkaido University
Development of noninvasive imaging biomarker for early diagnosis and prediction of outcome of intractable diseases of the central nervous system
- Principal Investigator
  
  THA KHIN KHIN
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Clinical and genetic analysis on neurodegenerative disordersPrincipal Investigator
- Principal Investigator
  
  YABE Ichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
Genome-wide screening of CNV in Multiple System Atrophy
- Principal Investigator
  
  SASAKI Hidenao
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
The study for the pathogenesis and surrogate markers of spinocerebellar degenerationPrincipal Investigator
- Principal Investigator
  
  YABE Ichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
Approach to find the susceptible genes for multiple sclerosis
- Principal Investigator
  
  KIKUCHI Seiji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
多系統萎縮症の発症素因解明に関する基礎的研究
- Principal Investigator
  
  SASAKI Hidenao
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
遺伝性脊髄小脳変性症の発症機序におけるproteinkinaseC機能の解明Principal Investigator
- Principal Investigator
  
  谷部一郎 (矢部一郎)
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
Causative gene mutation and molecular mechanism in spinooerebellar degeneration
- Principal Investigator
  
  SASAKI Hidenao
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  HOKKAIDO UNIVERSITY

[Book] 改訂第3版EBMに基づく脳神経疾患の基本2010
- Author(s)
  矢部一郎,佐木秀直
- Total Pages
  663
- Publisher
  メジカルビュ-社
- Data Source
  KAKENHI-PROJECT-21591067
[Book] 改訂第3版EBMに基づく脳神経疾患の基本2010
- Author(s)
  矢部一郎, 佐々木秀直
- Total Pages
  663
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-21591067
[Book] 2009-2010EBM神経疾患の治療2009
- Author(s)
  矢部一郎,佐木秀直
- Total Pages
  673
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21591067
[Book] 2009-2010EBM 神経疾患の治療2009
- Author(s)
  矢部一郎
- Total Pages
  673
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21591067
[Book] 遺伝性脊髄小脳変性症,改訂第二版 EBMに基づく脳神経疾患の基本治療(田村晃,松谷雅生,清水輝夫編)2006
- Author(s)
  矢部一郎, 佐々木秀直
- Publisher
  メジカルビュー社(印刷中)
- Data Source
  KAKENHI-PROJECT-16790481
[Book] TRHやTRH誘導体は本当に有効なのか,EBM 神経疾患の治療 2006-2007.)(岡本幸市,棚橋紀夫,水澤英洋編)2006
- Author(s)
  矢部一郎, 佐々木秀直
- Publisher
  中外医学社(印刷中)
- Data Source
  KAKENHI-PROJECT-16790481
[Journal Article] Moyamoya Disease Associated with a Deficiency of Complement Component 62022
- Author(s)
  Kato Masaru、Kudo Yuki、Hatase Masanao、Tsuchida Naohisa、Takeyama Shuhei、Sugiyama Taku、Fujimura Miki、Yabe Ichiro、Tsujimoto Hiroshi、Fukumori Yasuo、Inoue Norimitsu、Atsumi Tatsuya
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 31 Issue: 8 Pages: 106601-106601
- DOI
  10.1016/j.jstrokecerebrovasdis.2022.106601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Bassoon proteinopathy2021
- Author(s)
  脇田雅大、長井梓、矢口裕章、矢部一郎
- Journal Title
  
  脳神経内科
  
  Volume: 95 Pages: 482-488
- NAID
  40022724771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03585
[Journal Article] Rescue extracranial-intracranial bypass for ischemic stroke secondary to progressive human immunodeficiency virus-associated vasculopathy2021
- Author(s)
  Mizushima M, Sugiyama T, Eguchi K, Tarisawa M, Tokairin K, Ito M, Hashimoto D, Yabe I, Fujimura M
- Journal Title
  
  J Neurol Surg A Cent Eur Neurosurgery
  
  Volume: online ahead of print Issue: 01 Pages: 088-093
- DOI
  10.1055/a-1779-4142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Mutations in bassoon in individuals with familial and sporadic progressive supranuclear palsy-like syndrome2018
- Author(s)
  Yabe I, Yaguchi H, Kato Y, Miki Y, Takahashi H, Tanikawa S, Shirai S, Takahashi I, Kimura M, Hama Y, Matsushima M, Fujioka S, Kano T, Watanabe M, Nakagawa S, Kunieda Y, Ikeda Y, Hasegawa M, Nishihara H, Ohtsuka T, Tanaka S, Tsuboi Y, Hatakeyama S, Wakabayashi K, Sasaki H
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 819-819
- DOI
  10.1038/s41598-018-19198-0
- NAID
  120006377499
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09663, KAKENHI-PROJECT-16K09665, KAKENHI-PROJECT-17K19506, KAKENHI-PUBLICLY-17H05560, KAKENHI-PUBLICLY-17H05741, KAKENHI-PUBLICLY-17H05989, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-15H02356, KAKENHI-PROJECT-15H04272, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-17K19578
[Journal Article] Review in Syringomyelia2018
- Author(s)
  矢部一郎，佐々木秀直
- Journal Title
  
  Neurological Therapeutics
  
  Volume: 34 Issue: 4 Pages: 346-349
- DOI
  10.15082/jsnt.34.4_346
- NAID
  130006386606
- ISSN
  0916-8443, 2189-7824
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-17K09771
[Journal Article] A nationwide survey of familial syringomyelia in Japan2017
- Author(s)
  Yabe I, Matsushima M, Seki T, Sasaki H
- Journal Title
  
  J Neurol Sci
  
  Volume: 381 Pages: 128-129
- DOI
  10.1016/j.jns.2017.08.3237
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09771
[Journal Article] Writing errors in ALS related to loss of neuronal integrity in the anterior cingulate gyrus2012
- Author(s)
  Yabe, I., Tsuji-Akimoto, S., Shiga, T., Hamada, S., Hirata, K., Otsuki, M., Kuge, Y., Tamaki, N., Sasaki, H.
- Journal Title
  
  J Neurol Sci
  
  Volume: 315 Pages: 55-59
- NAID
  120003974403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Estimation of skeletal muscle energy metabolism in Machado-Joseph disease using (31)P-MR spectroscopy2012
- Author(s)
  Yabe I, Tha KK, Yokota T, Sato K, Soma H, Takei A, Terae S, Okita K, Sasaki H
- Journal Title
  
  Mov Disord
  
  Volume: 26巻 Pages: 165-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591067
[Journal Article] 脊髄小脳変性症の治療の進歩2012
- Author(s)
  矢部一郎, 佐木秀直
- Journal Title
  
  神経治療学
  
  Volume: 29(4)(掲載予定)
- NAID
  130006638879
- Data Source
  KAKENHI-PROJECT-21591067
[Journal Article] Writing errors in ALS related to loss of neurons integrity in the anterior cingulate gyrus2012
- Author(s)
  Yabe I, et al.
- Journal Title
  
  J Neurol Sci
  
  Volume: 315 Issue: 1-2 Pages: 55-59
- DOI
  10.1016/j.jns.2011.11.039
- NAID
  120003974403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Genetic analysis of two Japanese families with progressive external ophthalmoplegia and parkinsonism2011
- Author(s)
  Kazunori Sato, Ichiro Yabe, Hiroaki Yaguchi, Fumihito Nakano, Yasuyuki Kunieda, Shinji Saitoh, Hidenao Sasaki
- Journal Title
  
  J Neurol
  
  Volume: 258 Pages: 1327-32
- NAID
  120004405523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene : discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy2011
- Author(s)
  Sasaki H, Emi M, Iijima H, Ito N, Sato H, Yabe I, Kato T, Utsumi J, Matsubara K
- Journal Title
  
  Mol Brain
  
  Volume: 4巻
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591067
[Journal Article] Estimation of skeletal muscle energy metabolism in achado-Joseph disease using 31P-MR spectroscopy2011
- Author(s)
  Yabe I, et al.
- Journal Title
  
  Mov Disord
  
  Volume: 26 Issue: 1 Pages: 165-8
- DOI
  10.1002/mds.23335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Estimation of skeletal muscle energy metabolism in Machado-Joseph disease using 31P-MR spectroscopy2011
- Author(s)
  Ichiro Yabe, Khin K. Tha, Takashi Yokota, Kazunori Sato, Hiroyuki Soma, Asako Takei, Satoshi Terae^2, Koichi Okita, Hidenao Sasaki
- Journal Title
  
  Mov Disord
  
  Volume: 26 Pages: 165-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Estimation of skeletal muscle energy metabolism in Machado-Joseph disease using 31P-MR spectroscopy.2011
- Author(s)
  Yabe I, et al.
- Journal Title
  
  Movement Disorders
  
  Volume: 26 Pages: 165-168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Genetic analysis of two Japanese families with progressive external ophthalmoplegia and Parkinsonism2011
- Author(s)
  Sato K, Yabe I, et al.
- Journal Title
  
  J Neurol
  
  Volume: 258 Pages: 1327-32
- NAID
  120004405523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Microstructural white matter abnormalities of multiple system atrophy : in vivo topographic illustration by using diffusion-tensor MR imaging.2010
- Author(s)
  Tha KK, Yabe I, et al.
- Journal Title
  
  Radiology
  
  Volume: 255 Pages: 563-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Autosomal dominant cerebellar ataxia without pathogenic PPP2R2B mutation mans to SCA12 locus.2010
- Author(s)
  Sato K, Yabe I, et al.
- Journal Title
  
  Archives of Neurology
  
  Volume: 67 Pages: 1257-1262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Progressive anterior operculum syndrome due to FTLD-TDP : a clinico-pathological investigation.2010
- Author(s)
  Otsuki M, Yabe I, et al.
- Journal Title
  
  Journal of Neurology
  
  Volume: 257 Pages: 1148-1153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] MERRF/MELAS overlap syndrome : A double pathogenic mutation in mitochondrial tRNA genes.2010
- Author(s)
  Yabe I, et al.
- Journal Title
  
  Journal of Medical Genetics
  
  Volume: 47 Pages: 659-664
- NAID
  120002722535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] Mapping of autosomal dominant cerebellar ataxia without pathogenic PPP2R2B mutation to the locus for spinocerebellar ataxia 122010
- Author(s)
  Sato K, Yabe I, Fukuda Y, Soma H, Nakahara Y, Tsuji S, Sasaki H
- Journal Title
  
  ArchNeurol
  
  Volume: 67巻 Pages: 1257-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591067
[Journal Article] Microstructural white matter abnormalities of multiple system atrophy : in vivo topographic illustration by using diffusion-tensor MR imaging2010
- Author(s)
  Tha KK, Terae S, Yabe I, Miyamoto T, Soma H, Zaitsu Y, Fujima N, Kudo K, Sasaki H, Shirato H
- Journal Title
  
  Radiology
  
  Volume: 255巻 Pages: 563-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591067
[Journal Article] Unusual retinal phenotypes in an SCA7 family2009
- Author(s)
  Inaba H, Yabe I, Yashima M, Soma H, Nakamura Y, Houzen H, Sasaki H
- Journal Title
  
  Intern Med
  
  Volume: 48巻 Pages: 1461-1464
- NAID
  130000122034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591067
[Journal Article] 新しい小脳性運動失調の重症度評価スケールScalefor the Assessment and Rating of Ataxia(SARA) 日本語版の信頼性に関する検討2009
- Author(s)
  佐藤和則, 矢部一郎, 相馬広幸, 安井建一, 伊藤瑞規, 下畑亨良, 小野寺理, 中島健二, 祖父江元, 西澤正豊, 佐木秀直
- Journal Title
  
  Brain and Nerve
  
  Volume: 61巻 Pages: 591-595
- NAID
  40016669037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591067
[Journal Article] Usefulness of the Scale for Assessment and Rating of Ataxia (SARA)2008
- Author(s)
  Yabe I
- Journal Title
  
  Journal of the Neurological Sciences 266
  
  Pages: 164-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590974
[Journal Article] Downbeat positioning nystagmus is a common clinical feature despite variable phenotypes in an FHM1 family2008
- Author(s)
  Yabe I
- Journal Title
  
  Journal of Neurology 255
  
  Pages: 1541-1544
- NAID
  120001600870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590974
[Journal Article] Downbeat positioning nystagmus is a common clinical feature despite variable phenotypes in an FHM1 family2008
- Author(s)
  Yabe I, Kitagawa M, Suzuki Y, Fujiwara K, Wada T, Tsubuku T, Takeichi N, Sakushima K, Soma H, Tsuji S, Niino M, Saitoh S, Sasaki H
- Journal Title
  
  J Neurol 255
  
  Pages: 1541-1544
- NAID
  120001600870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590974
[Journal Article] Spectrum and prevalence of autosomal dominant spinocerebellar ataxia in Hokkaido, the northern island of Japan : a study of 113 Japanese families2007
- Author(s)
  Yabe I, Basri R, Soma H, Sasaki H
- Journal Title
  
  J Hum Genet 52
  
  Pages: 848-855
- NAID
  10019776420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590974
[Journal Article] 脊髄小脳変性症の薬物療法2006
- Author(s)
  矢部一郎
- Journal Title
  
  難病と在宅ケア (印刷中)
- Data Source
  KAKENHI-PROJECT-16790481
[Journal Article] Hereditary in multiple system atrophy2006
- Author(s)
  Soma, H., Yabe, I., Takei, A., Fujiki, N., Yanagihara, T., Sasaki, H.
- Journal Title
  
  J Neurol Sci 240(1-2)
  
  Pages: 107-110
- Data Source
  KAKENHI-PROJECT-16790481
[Journal Article] Heredity in multiple system strophy2006
- Author(s)
  Soma H, Yabe I, Takei A, Fujiki N, Yanagihara T, Sasaki H
- Journal Title
  
  J Neurol Sci 240・1-2
  
  Pages: 107-110
- Data Source
  KAKENHI-PROJECT-16659227
[Journal Article] MSA-C is the predominant clinical phenotype of MSA in Japan : Analysis of 142 patients with probable MSA.2006
- Author(s)
  Yabe I
- Journal Title
  
  J Neurol Sci 249
  
  Pages: 115-121
- NAID
  120000958283
- Data Source
  KAKENHI-PROJECT-16659227
[Journal Article] The clinical and genetic spectrum of spinocerebellar ataxia 142005
- Author(s)
  Chen, D.H., Cimino, P.J., Ranum, L.P.W., Zoghbi, H.Y., Yabe, I., Schut, L., Margolis, R.L., Lipe, H.P., Feleke, A., Matsushita M., Wolff, J., Morgan, C., Lau, D., Fernandez, M., Sasaki, H., Raskind, W.H., Bird, T.D.
- Journal Title
  
  Neurology 64(7)
  
  Pages: 1258-1260
- Data Source
  KAKENHI-PROJECT-16790481
[Journal Article] Treatment of cerebellar ataxia with 5-HT1A agonist.2005
- Author(s)
  TaKei, A., Hamada, T., Yabe, I., Sasaki, H.
- Journal Title
  
  Cerebellum 4(3)
  
  Pages: 211-215
- Data Source
  KAKENHI-PROJECT-16790481
[Journal Article] No association between FMR1 premutations and multiple system atrophy.2004
- Author(s)
  Yabe I
- Journal Title
  
  Journal of Neurology 251
  
  Pages: 1411-1412
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] No association between FMR1 premutations and multiple system atrophy2004
- Author(s)
  Yabe I
- Journal Title
  
  Journal of Neurology 251
  
  Pages: 1411-1412
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] No association between FMR1 and multiple system atrophy2004
- Author(s)
  矢部一郎
- Journal Title
  
  Journal of Neurology 251
  
  Pages: 1411-1412
- Data Source
  KAKENHI-PROJECT-16790481
[Journal Article] Spinocerebellar ataxia type 142004
- Author(s)
  矢部一郎
- Journal Title
  
  神経内科 60
  
  Pages: 493-496
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] No association between FMR1 premutaions and multiple system atrophy2004
- Author(s)
  Yabe I
- Journal Title
  
  Journal of Neurology 251
  
  Pages: 1411-1412
- Data Source
  KAKENHI-PROJECT-16659227
[Journal Article] Spinocerebellar ataxia type 142004
- Author(s)
  矢部一郎
- Journal Title
  
  神経内科 60
  
  Pages: 493-496
- Data Source
  KAKENHI-PROJECT-16659227
[Journal Article] Spinocerebellar ataxia type142004
- Author(s)
  矢部一郎
- Journal Title
  
  神経内科 60
  
  Pages: 493-496
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Spinocerebellar ataxia type 142004
- Author(s)
  矢部一郎
- Journal Title
  
  神経内科 60
  
  Pages: 493-496
- Data Source
  KAKENHI-PROJECT-16790481
[Journal Article] Spinocerebellar ataxia type 14.2004
- Author(s)
  Yabe I
- Journal Title
  
  Neurological Medicine 60
  
  Pages: 493-496
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Positional Vertigo and Macroscopic Downbeat Positioning Nystagmus in Spinocerebellar Ataxia Type 6 (SCA6).2003
- Author(s)
  Yabe I
- Journal Title
  
  Journal of Neurology 250
  
  Pages: 440-443
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Spinocerebellar ataxia type 6 (SCA6)の臨床像についての再考2003
- Author(s)
  矢部一郎
- Journal Title
  
  脳と神経 55
  
  Pages: 299-306
- NAID
  40019912954
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Spinocerebellar ataxia type 14 caused by a mutation in protein kinase C γ.2003
- Author(s)
  Yabe I
- Journal Title
  
  Archives of Neurology 60
  
  Pages: 1749-1751
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Re-evaluation of clinical presentation in Spinocerebellar ataxia type6.2003
- Author(s)
  Yabe I
- Journal Title
  
  Brain and Nerve 55
  
  Pages: 299-306
- NAID
  40019912954
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Spinocerebellar ataxia type 14 caused by a mutation in protein kinase C γ2003
- Author(s)
  Yabe I
- Journal Title
  
  Archives of neurology 60
  
  Pages: 1749-1751
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Positional Vertigo and Macroscopic Downbeat Positioning Nystagmus in Spinocerebellar Ataxia Type 6 (SCA6)2003
- Author(s)
  Yabe I
- Journal Title
  
  Journal of neurology 250
  
  Pages: 440-443
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Late onset ataxia phenotype in dentatorubropallidoluysian atrophy (DRPLA)2002
- Author(s)
  Yabe I
- Journal Title
  
  Journal of Neurology 249(4)
  
  Pages: 432-436
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] 家族性発作性小脳失調症 a.ミオキミアを伴わない発作性小脳失調症2002
- Author(s)
  矢部一郎
- Journal Title
  
  日本臨床 2002年別冊「神経症候群VI」別冊
  
  Pages: 322-325
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Episodic ataxia without myokymia.2002
- Author(s)
  Yabe I
- Journal Title
  
  Ryouikibetsu Shoukougun Shiriizu 37 Pt 6
  
  Pages: 322-325
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Spastin gene mutation in Japanese with hereditary spastic paraplegia.2002
- Author(s)
  Yabe I
- Journal Title
  
  Journal of Neurology 39(8)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Spastin gene mutation in Japanese with hereditary sapstic paraplegia2002
- Author(s)
  Yabe I
- Journal Title
  
  Journal of medical genetics 39(8)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Late onset ataxia phenotype in dentatorubro-pallidoluysian atrophy (DRPLA).2002
- Author(s)
  Yabe I
- Journal Title
  
  Journal of Neurology 294(4)
  
  Pages: 432-436
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370202
[Journal Article] Genetic analysis of two Japanese families with progressive external ophthalmoplegia and parkinsonism.
- Author(s)
  Sato K, Yabe I, et al.
- Journal Title
  
  Journal of Neurology
  
  Volume: (In press)
- NAID
  120004405523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Journal Article] MERRF/MELAS overlap syndrome : A double pathogenic mutation in mitochondrial tRNA genes.
- Author(s)
  Yabe I
- Journal Title
  
  Journal of Medical Genetics (In press)
- NAID
  120002722535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591066
[Patent] 神経変性疾患の検査方法2011
- Inventor(s)
  佐木秀直、矢部一郎
- Industrial Property Rights Holder
  国立大学法人北海道大学
- Acquisition Date
  2011-02-21
- Data Source
  KAKENHI-PROJECT-21591067
[Presentation] もやもや病のエピゲノム病態修飾因子＜血漿microRNA＞探索2024
- Author(s)
  伊東雅基、内野晴登、東海林菊太郎、杉山拓、川堀真人、岩田育子、矢部一郎、寳金清博、藤村幹
- Organizer
  第53回日本脳卒中の外科学会学術集会シンポジウム 02 (卒外SY02)
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] Pathological study of PSP-like syndrome cases with mutations in BSN and BSN knock-in mice2023
- Author(s)
  Hiroaki Yaguchi, Masahiro Wakita, Mika Otuski, Satoshi Tanikawa, Yasuo Miki, Akihiko Kudo, Azusa Nagai, Hisashi Uwatoko, Yasunori Mito, Kaichi Yoshizaki, Taichi Hara, Takeshi Ikeuchi, Shinya Tanaka, Koichi Wakabayashi, Ichiro Yabe
- Organizer
  日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27511
[Presentation] The Role of Electric Properties Tomography in Biochemical Analysis of the Cerebrospinal Fluid and Parameter Optimization for Improved Accuracy2022
- Author(s)
  Tha KK, Katscher U, Hamaguchi H, Li X, Kawasaki T, Yamaguchi S, Yabe I, Hyodoh H
- Organizer
  Joint Annual Meeting ISMRM-ESMRMB
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12590
[Presentation] BSN遺伝子変異例におけるタンパク質品質管理の病理学的検討とモデルマウス作製2022
- Author(s)
  矢口裕章，脇田雅大, 長井　梓，白井慎一,岩田育子,松島理明,三木康生，原　太一，吉崎嘉一，高橋秀尚，若林　孝一,矢部一郎
- Organizer
  第63回神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20H03585
[Presentation] Biochemical Analysis of the Cerebrospinal Fluid Using Electric Properties Tomography.2022
- Author(s)
  Tha KK, Katscher U, Hamaguchi H, Li X, Kawasaki T, Yamaguchi S, Yabe I, Hyodoh H.
- Organizer
  2022 Joint Workshop on MR phase, magnetic susceptibility and electrical properties mapping
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12590
[Presentation] Mutation analysis of BSN gene in patients with multiple system atrophy2021
- Author(s)
  M. Wakita, A. Nagai, H. Yaguchi, I. Yabe.
- Organizer
  MDS Virtual Congress 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03585
[Presentation] Noninvasive Assessment Of The Cerebrospinal Fluid Composition By MRI: Does Electric Properties Tomography Have A Role?2021
- Author(s)
  Tha KK, Katscher U, Yabe I, Hyodoh H
- Organizer
  he 107th Scientific Assembly and Annual Meeting of the Radiological Society of North America
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12590
[Presentation] Genetic aspects of typical and atypical tauopathy2020
- Author(s)
  Yabe I
- Organizer
  61st Annual Meeting of Japanese Neurological Association
- Invited
- Data Source
  KAKENHI-PROJECT-20H03585
[Presentation] Identification of a gene associated with PSP2019
- Author(s)
  矢部一郎
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09663
[Presentation] A part of tauopathy may be caused by mutations in bassoon.2018
- Author(s)
  Yabe I, Yaguchi H, Kato Y, Miki Y, Takahashi H, Shirai S, Takahashi I, Kano T, Fujioka S, Watanabe M, Nakagawa S, Kunieda Y, Ikeda Y, Hasegawa M, Nishihara H, Tanaka S, Tsuboi Y, Hatakeyama S, Wakabayashi K, Sasaki H.
- Organizer
  第59回日本神経学会学術大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09663
[Presentation] Mutations in bassoon in individuals with familial and sporadic progressive supranuclear palsy-like syndrome2017
- Author(s)
  Yabe I, Yaguchi H, Kato Y, Miki Y, Takahashi H, Tanikawa S, Shirai S, Takahashi I, Fujioka S, Watanabe M, Nakagawa S, Kunieda Y, Ikeda Y, Hasegawa M, Nishihara H, Tanaka S, Tsuboi Y, Hatakeyama S, Wakabayashi K, Sasaki H
- Organizer
  23rd World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09663
[Presentation] 家族性進行性核上性麻痺症候群家系の遺伝子解析結果に基づいた孤発性進行性核上性麻痺の遺伝子解析研究2016
- Author(s)
  矢部一郎　他
- Organizer
  第57回日本神経学会学術集会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-16K09663
[Presentation] Regional DTI metrics of the cervical spinal cord in sporadic amyotrophic lateral sclerosis2014
- Author(s)
  Tha KK, Yabe I, Terae S, Hirotani M, Hamaguchi H, Suzuki Y, Okuaki T, Minowa K, Sasaki H, Shirato H
- Organizer
  第73回日本放射線学会
- Place of Presentation
  Pacifico Yokohama（横浜）
- Data Source
  KAKENHI-PROJECT-23791380
[Presentation] Regional DTI metrics of the cervical spinal cord in sporadic amyotrophic lateral sclerosis2014
- Author(s)
  Tha KK, Yabe I, Terae S, Hirotani M, Hamaguchi H, Suzuki Y, Okuaki T, Minowa K, Sasaki H, Shirato H.
- Organizer
  第73回日本放射線学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791380
[Presentation] The ascending sensory pathways may not be spared in amyotrophic lateral sclerosis2013
- Author(s)
  Tha KK, Yabe I, Terae S , Hirotani M, Hamaguchi H, Ishizaka K, Suzuki Y, Okuaki T, Minowa K, Sasaki H, Shirato H.
- Organizer
  The 11^<th> International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23791380
[Presentation] The ascending sensory pathways may not be spared in amyotrophic lateral sclerosis2013
- Author(s)
  Tha KK, Yabe I, Terae S, Hirotani M, Hamaguchi H, Ishizaka K, Suzuki Y, Okuaki T, Minowa K, Sasaki H, Shirato H
- Organizer
  The 11th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Science Bldg. No. 5, 2nd Floor, Graduate School of Science, Hokkaido University　（札幌）
- Data Source
  KAKENHI-PROJECT-23791380
[Presentation] ALSにおける11C-フルマゼニル(FMZ)-PET所見2011
- Author(s)
  矢部一郎
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場,愛知
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21591066
[Presentation] 進行性外眼筋麻痺を伴ったパーキンソニズムの遺伝子解析2011
- Author(s)
  佐藤和則、矢口裕章、加納崇裕、矢部一郎、佐木秀直、國枝保幸
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場、愛知
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21591066
[Presentation] ALSにおける11C-フルマゼニル(FMZ)-PET所見2011
- Author(s)
  矢部一郎、秋本幸子、大槻美佳、志賀哲、玉木長良、佐木秀直
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場、愛知
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21591066
[Presentation] 一卵性双生児CNV解析による多系統萎縮症のゲノムコピー数異常の同定2011
- Author(s)
  佐木秀直,矢部一郎,加藤丈夫,江見充,飯島寛,伊東紀子,佐藤秀則
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21591067
[Presentation] 多系統萎縮症(MSA)におけるSHC2遺伝子コピー数(CNV)異常2011
- Author(s)
  石井美穂,江見充,飯島寛,伊東紀子,佐藤秀則,加藤丈夫,矢部一郎,佐木秀直
- Organizer
  日本人類遺伝学会第56回大会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-21591067
[Presentation] ポリグルタミン病の筋エネルギー代謝2010
- Author(s)
  矢部一郎
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-21591066
[Presentation] MSA疾患感受性候補遺伝子の関連解析2010
- Author(s)
  相馬広幸,佐藤和則,矢部一郎,佐木秀直
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム(東京)
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-21591067
[Presentation] SCA12遺伝子座に連鎖しているがPPP2R2Bの変異を認めないADCAの1家系2010
- Author(s)
  佐藤和則,矢部一郎,相馬広幸,佐木秀直,福田陽子,三井純,中原康雄,辻省次
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム(東京)
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21591067
[Presentation] 日本語版SARAを用いた多系統萎縮症の経時的評価2009
- Author(s)
  佐藤和則,相馬広幸,矢部一郎,佐木秀直
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21591067
[Presentation] ポリグルタミン病の筋エネルギー代謝2009
- Author(s)
  矢部一郎
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台市国際センター
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21591066
[Presentation] Skeletal muscle energy metabolism in Machado-Joseph disease2008
- Author(s)
  Yabe I, Tha K K, Terae S, Okita K, Sasaki H
- Organizer
  12^<th>International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  Hilton Chicago, Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-19590974
[Presentation] ポリグルタミン病における筋エネルギー代謝測定-第2報2008
- Author(s)
  矢部一郎, Tha Khin Khin, 寺江聡, 沖田孝一, 佐々木秀直
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19590974
[Presentation] Skeletal muscle energy metabolism in Machado-Joseph disease2008
- Author(s)
  Yabe I
- Organizer
  12^<th> International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  Hilton Cicago
- Year and Date
  2008-06-25
- Data Source
  KAKENHI-PROJECT-19590974
[Presentation] ポリグルタミン病における筋エネルギー代謝測定-第2報2008
- Author(s)
  矢部一郎
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19590974
[Presentation] ポリグルタミン病における筋エネルギー代謝測定の試み2007
- Author(s)
  矢部一郎
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19590974
[Presentation] Usefulness of the scale for assessment and rating of ataxia (SARA)2007
- Author(s)
  Yabe I
- Organizer
  11^<th> International Congress of Parkinson's Disease and Movement Disorders
- Place of Presentation
  Istanbul Convention and Exhibition Centre
- Year and Date
  2007-06-05
- Data Source
  KAKENHI-PROJECT-19590974
[Presentation] Contribution of the cerebellum to perceptual prediction. (知覚的予測における小脳の役割)
- Author(s)
  Matsushima, A., Itoh, S., Yoshida, A., Kurkin, S., Yabe, I., Sasaki, H., Tanaka, M.
- Organizer
  日本神経科学学会
- Place of Presentation
  京都国際会館（京都市）
- Data Source
  KAKENHI-PROJECT-24500455

1. SASAKI Hidenao (80281806)

# of Collaborated Projects: 8 results

# of Collaborated Products: 27 results
2. TSUJI Sachiko (60374328)

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Yabe Ichiro 矢部 一郎

YABE Ichiro 矢部 一郎

谷部 一郎 ヤベ イチロウ

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Mechanism analysis research of Bassoon proteinopathyPrincipal Investigator

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Pathophysiological study of Bassoon proteinopathyPrincipal Investigator

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Pathomechanism study of progressive supranuclear palsy based on genetic analysis in familial progressive supranuclear palsyPrincipal Investigator

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Clinical and genetic analysis on neurodegenerative disordersPrincipal Investigator

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Yabe Ichiro 矢部一郎

YABE Ichiro 矢部一郎

谷部一郎ヤベイチロウ

[Book] 遺伝性脊髄小脳変性症,改訂第二版 EBMに基づく脳神経疾患の基本治療(田村晃,松谷雅生,清水輝夫編)2006