Iida Madoka 飯田円

Researcher Number	40815437
Other IDs	https://orcid.org/0000-0002-3394-9760
Affiliation (Current)	2025: 名古屋大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 名古屋大学, 医学系研究科, 助教 2018 – 2019: 名古屋大学, 医学系研究科, 学振特別研究員(RPD)
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / 0704:Neuroscience, brain sciences, and related fields / Basic Section 51030:Pathophysiologic neuroscience-related Except Principal Investigator Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator 球脊髄性筋萎縮症 / マウスモデル / 細胞モデル / in silico解析 / 治療薬開発 / In silico解析 / 骨格筋病態 / 運動ニューロン疾患 / 超早期病態 / 興奮毒性 … More / シナプス / イオンチャネル / オリゴデンドロサイト / シングルセル解析 / 運動ニューロンネットワーク変性 / 感覚ニューロン / 後根神経節 / アンドロゲン受容体 / Srcシグナル / Cre-loxPシステム / SBMA / Src阻害薬 / Srcシグナル異常 … More Except Principal Investigator 運動ニューロン / オリゴデンドロサイト / TDP-43 / 筋萎縮性側索硬化症 / イオンチャンネル / 転写障害 / 早期病態 / 球脊髄性筋萎縮症 / 神経変性疾患 / シングルセル解析 / 胎児 / マルチモーダル解析 / 運動ニューロン疾患 Less

球脊髄性筋萎縮症の運動ニューロン病態におけるアストロサイト脂質代謝異常の役割Principal Investigator
- Principal Investigator
  
  飯田円
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nagoya University
ALSに関連する運動ニューロン周囲オリゴデンドロサイトの機能と役割の解明
- Principal Investigator
  
  井口洋平
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagoya University
Elucidation of temporal alteration in motor neuron-oligodendrocyte interaction in motor neuron diseases
- Principal Investigator
  
  勝野雅央
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagoya University
Exploring skeletal muscle pathology in spinal and bulbar muscular atrophy using in silico analysis.Principal Investigator
- Principal Investigator
  
  Iida Madoka
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nagoya University
Elucidation of the pathogenesis of spinal and bulbar muscular atrophy by single cell RNA-seq analysisPrincipal Investigator
- Principal Investigator
  
  Iida Madoka
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0704:Neuroscience, brain sciences, and related fields
- Research Institution
  Nagoya University
Molecular mechanisms of neurocircuit in motor neuron diseasesPrincipal Investigator
- Principal Investigator
  
  Iida Madoka
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nagoya University

All 2024 2023 2022 2021 2019 2018

All Journal Article Presentation Book

[Book] CLINICAL NEUROSCIENCE2022
- Author(s)
  飯田　円
- Total Pages
  3
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22K15705
[Journal Article] Autoantibodies Against Dihydrolipoamide S-Acetyltransferase in Immune-Mediated Neuropathies.2024
- Author(s)
  Fukami Y, Iijima M, Koike H, Yagi S, Furukawa S, Mouri N, Ouchida J, Murakami A, Iida M, Yokoi S, Hashizume A, Iguchi Y, Imagama S, Katsuno M.
- Journal Title
  
  Neurol Neuroimmunol Neuroinflamm.
  
  Volume: 11(2) Issue: 2
- DOI
  10.1212/nxi.0000000000200199
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14751, KAKENHI-PROJECT-23K06926, KAKENHI-PROJECT-22K19506, KAKENHI-PROJECT-22K15705
[Journal Article] Exercise attenuates polyglutamine-mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy.2024
- Author(s)
  Hirunagi T, Nakatsuji H, Sahashi K, Yamamoto M, Iida M, Tohnai G, Kondo N, Yamada S, Murakami A, Noda S, Adachi H, Sobue G, Katsuno M.
- Journal Title
  
  J Cachexia Sarcopenia Muscle
  
  Volume: 15 Issue: 1 Pages: 159-172
- DOI
  10.1002/jcsm.13344
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06976, KAKENHI-PROJECT-22K15705, KAKENHI-PROJECT-23H00420
[Journal Article] Dysregulation of Aldh1a2 underlies motor neuron degeneration in spinal muscular atrophy2023
- Author(s)
  Kataoka Mayumi、Sahashi Kentaro、Tsujikawa Koyo、Takeda Jun-ichi、Hirunagi Tomoki、Iida Madoka、Katsunoa Masahisa
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 58-65
- DOI
  10.1016/j.neures.2023.04.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K20686, KAKENHI-PROJECT-22K15705
[Journal Article] Label-free morphological sub-population cytometry for sensitive phenotypic screening of heterogenous neural disease model cells2022
- Author(s)
  Imai Yuta、Iida Madoka、Kanie Kei、Katsuno Masahisa、Kato Ryuji
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 9296-9296
- DOI
  10.1038/s41598-022-12250-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15705, KAKENHI-PROJECT-20H00527, KAKENHI-PROJECT-21K20686
[Journal Article] Clinical implication of denervation in sporadic inclusion body myositis2022
- Author(s)
  Noda Seiya、Murakami Ayuka、Kazuta Tomoyuki、Hirano Satoko、Kimura Seigo、Nakanishi Hirotaka、Matsuo Koji、Tsujikawa Koyo、Yamada Shinichiro、Iida Madoka、Koike Haruki、Kuru Satoshi、Katsuno Masahisa
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 439 Pages: 120317-120317
- DOI
  10.1016/j.jns.2022.120317
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15705, KAKENHI-PROJECT-21K20686
[Journal Article] Metabolome and transcriptome analysis on muscle of sporadic inclusion body myositis.2022
- Author(s)
  Murakami, A., Noda, S., Kazuta, T., Hirano, S., Kimura, S., Nakanishi, H., Matsuo, K., Tsujikawa, K., Iida, M., Koike, H., Sakamoto, K., Hara, Y., Kuru, S., Kadomatsu, K., Shimamura, T., Ogi, T., Katsuno, M.
- Journal Title
  
  Ann Clin Transl Neurol.
  
  Volume: 9 Issue: 10 Pages: 1602-1615
- DOI
  10.1002/acn3.51657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18251, KAKENHI-PROJECT-22K15705, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-20K21832, KAKENHI-PROJECT-21K20686, KAKENHI-PUBLICLY-22H04839
[Journal Article] Mid1 is associated with androgen-dependent axonal vulnerability of motor neurons in spinal and bulbar muscular atrophy2022
- Author(s)
  Ogura Yosuke、Sahashi Kentaro、Hirunagi Tomoki、Iida Madoka、Miyata Takaki、Katsuno Masahisa
- Journal Title
  
  Cell Death & Disease
  
  Volume: 13 Issue: 7 Pages: 601-601
- DOI
  10.1038/s41419-022-05001-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15705, KAKENHI-PROJECT-20H00527, KAKENHI-PROJECT-21H02656, KAKENHI-PROJECT-21K20686, KAKENHI-PUBLICLY-21H00363
[Journal Article] Selective suppression of polyglutamine-expanded protein by lipid nanoparticle-delivered siRNA targeting CAG expansions in the mouse CNS.2021
- Author(s)
  Hirunagi T, Sahashi K, Tachikawa K, Leu AI, Nguyen M, Mukthavaram R, Karmali PP, Chivukula P, Tohnai G, Iida M, Onodera K, Ohyama M, Okada Y, Okano H, Katsuno M.
- Journal Title
  
  Mol Ther Nucleic Acids.
  
  Volume: 24 Pages: 1-10
- DOI
  10.1016/j.omtn.2021.02.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00527, KAKENHI-PROJECT-18K07539, KAKENHI-PROJECT-19K07969, KAKENHI-PROJECT-21K07471, KAKENHI-PROJECT-17K19465, KAKENHI-PROJECT-21K20686, KAKENHI-PROJECT-19H03576
[Journal Article] A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue-induced cocaine craving following prolonged abstinence.2021
- Author(s)
  Mitra S, Gobira PH, Werner CT, Martin JA, Iida M, Thomas SA, Erias K, Miracle S, Lafargue C, An C, Dietz DM.
- Journal Title
  
  Addict Biol.
  
  Volume: 26 Issue: 5
- DOI
  10.1111/adb.13007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20686
[Journal Article] Ratio of urinary N-terminal titin fragment to urinary creatinine is a novel biomarker for amyotrophic lateral sclerosis2021
- Author(s)
  Yamada Shinichiro、Hashizume Atsushi、Hijikata Yasuhiro、Ito Daisuke、Kishimoto Yoshiyuki、Iida Madoka、Koike Haruki、Hirakawa Akihiro、Katsuno Masahisa
- Journal Title
  
  Journal of Neurology, Neurosurgery & Psychiatry
  
  Volume: 92 Issue: 10 Pages: 1072-1079
- DOI
  10.1136/jnnp-2020-324615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15693, KAKENHI-PROJECT-21K20686
[Journal Article] Elevated serum creatine kinase in the early stage of sporadic amyotrophic lateral sclerosis.2019
- Author(s)
  Ito D, Hashizume A, Hijikata Y, Yamada S, Iguchi Y, Iida M, Kishimoto Y, Moriyoshi H, Hirakawa A, Katsuno M.
- Journal Title
  
  J Neurol.
  
  Volume: 266 Issue: 12 Pages: 2952-2961
- DOI
  10.1007/s00415-019-09507-6
- NAID
  120006786260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-17J40128, KAKENHI-PROJECT-17K09753, KAKENHI-PROJECT-18K15361
[Journal Article] Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy2019
- Author(s)
  Iida Madoka、Sahashi Kentaro、Kondo Naohide、Nakatsuji Hideaki、Tohnai Genki、Tsutsumi Yutaka、Noda Seiya、Murakami Ayuka、Onodera Kazunari、Okada Yohei、Nakatochi Masahiro、Tsukagoshi Okabe Yuka、Shimizu Shinobu、Mizuno Masaaki、Adachi Hiroaki、Okano Hideyuki、Sobue Gen、Katsuno Masahisa
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 4262-4262
- DOI
  10.1038/s41467-019-12282-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-18K16656, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-17J40128, KAKENHI-PROJECT-18K15361
[Journal Article] DNA methylation inhibitor attenuates polyglutamine-induced neurodegeneration by regulating Hes52019
- Author(s)
  Kondo N, Tohnai G, Sahashi K, Iida M, Kataoka M, Nakatsuji H, Tsutsumi Y, Hashizume A, Adachi H, Koike H, Shinjo K, Kondo Y, Sobue G, Katsuno M.
- Journal Title
  
  EMBO Mol Med
  
  Volume: none Issue: 5
- DOI
  10.15252/emmm.201708547
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H04195, KAKENHI-PROJECT-19K07970, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-17J40128, KAKENHI-PROJECT-18K15361
[Presentation] Single cell analysis reveals oligodendrocyte heterogeneity in spinal and bulbar muscular atrophy2023
- Author(s)
  Madoka Iida
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K20686
[Presentation] Single cell analysis reveals oligodendrocyte heterogeneity in spinal and bulbar muscular atrophy2023
- Author(s)
  飯田　円
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K15705
[Presentation] Single cell analysis reveals oligodendrocyte heterogeneity in spinal and bulbar muscular atrophy2023
- Author(s)
  Madoka Iida
- Organizer
  CAG Triplet Repeat Disorders Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20686
[Presentation] Single cell analysis reveals oligodendrocyte heterogeneity in spinal and bulbar muscular atrophy2023
- Author(s)
  飯田円, 佐橋健太郎, 蛭薙智紀, 榊原健二, 前田憲多郎, 紅朋浩, 日野原邦彦, 勝野雅央
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-23H00420
[Presentation] Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy2019
- Author(s)
  Madoka Iida, Kentaro Sahashi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Gen Sobue, Masahisa Katsuno
- Organizer
  AMED-MRCシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15361
[Presentation] Molecular mechanisms of neuromuscular degeneration in spinal and bulbar muscular atrophy2019
- Author(s)
  Madoka Iida
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K15361
[Presentation] Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy2019
- Author(s)
  Madoka Iida, Kentaro Sahashi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Masahisa Katsuno
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K15361
[Presentation] Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy2019
- Author(s)
  Madoka Iida, Kentaro Sahashi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Masahisa Katsuno
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K15361
[Presentation] Development of the therapeutics targeting the spatiotemporal dysregulation of signaling pathways in spinal and bulbar muscular atrophy2018
- Author(s)
  Madoka Iida, Kentaro Sahashi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Yutaka Tsutsumi, Masahisa Katsuno
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K15361
[Presentation] Development of the therapeutics targeting the spatiotemporal dysregulation of signaling pathways in spinal and bulbar muscular atrophy2018
- Author(s)
  Madoka Iida, Kentaro Sahashi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Yutaka Tsutsumi, Masahisa Katsuno
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K15361

1. 勝野雅央 (50402566)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 佐橋健太郎 (90710103)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 井口洋平 (80790659)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 蛭薙智紀 (00927527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 横井聡 (30815460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ADACHI Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 橋詰淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 門松健治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 深見祐樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 山田晋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Iida Madoka 飯田 円

Research Projects

Research Products

Co-Researchers

球脊髄性筋萎縮症の運動ニューロン病態におけるアストロサイト脂質代謝異常の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ALSに関連する運動ニューロン周囲オリゴデンドロサイトの機能と役割の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of temporal alteration in motor neuron-oligodendrocyte interaction in motor neuron diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring skeletal muscle pathology in spinal and bulbar muscular atrophy using in silico analysis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of spinal and bulbar muscular atrophy by single cell RNA-seq analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of neurocircuit in motor neuron diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] CLINICAL NEUROSCIENCE2022

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Autoantibodies Against Dihydrolipoamide S-Acetyltransferase in Immune-Mediated Neuropathies.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exercise attenuates polyglutamine-mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dysregulation of Aldh1a2 underlies motor neuron degeneration in spinal muscular atrophy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Label-free morphological sub-population cytometry for sensitive phenotypic screening of heterogenous neural disease model cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical implication of denervation in sporadic inclusion body myositis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolome and transcriptome analysis on muscle of sporadic inclusion body myositis.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mid1 is associated with androgen-dependent axonal vulnerability of motor neurons in spinal and bulbar muscular atrophy2022

Author(s)

Journal Title

DOI

Data Source

Iida Madoka 飯田円