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MATSUZAWA Akio  松沢 昭雄

ORCIDConnect your ORCID iD *help
Researcher Number 50012745
External Links
Affiliation (based on the past Project Information) *help 1998 – 1999: Inst.Med.Sci., Tokyo Univ., Professor, 医科学研究所, 教授
1998: 東京大学, 医科学研究科, 教授
1998: 東京大学医科学研究所, 教授
1997 – 1998: 東京大学, 医科研, 助教授
1986 – 1997: 東京大学, 医科学研究所, 助教授
1986: 東大, 医科学研究所, 助教授
1985: 東京大学, 医科研, 助教授
Review Section/Research Field
Principal Investigator
Experimental pathology
Except Principal Investigator
General surgery / 内科学一般 / Ophthalmology / Laboratory animal science / Digestive surgery / Experimental pathology
Keywords
Principal Investigator
自己免疫病 / lpr^<cg>遺伝子 / リンパ節腫脹 / 進展 / マウス乳癌 / lpr^<cg> gene / Autoimmune disease / gld遺伝子 / IV型コラーゲン / IL-12 … More / Gene therapy / Superantigen / スーパー抗原 / 糸球体腎炎 / MRL mice / 相補作用 / MRLマウス / Autoantibody / Lymphadenopathy / 自己抗体 / マウス / 基底膜 / オンコジーン / ホルモン依存性 / 染色体異常 / 自律性増殖 / ホルモン / 遺伝子治療 / hormone-dependent mammary tumor / autoimmune disease / lens / hereditary cataract / early development / kidney / mice / type IV collagen / Basement membrane / コンパクション / マウス初期発生 / マウス腎臓 / 【IV】型コラーゲン / 転移 / 自律性獲得 / ホルモン依存性乳癌 / 水晶体 / 遺伝性白内障 / 初期発生 / 腎臓 / Lympadenopathy / Glomerulonephritis / MRL-lprィイD1cgィエD1 mice / 免疫複合体 / 可溶性CD4 / CD4欠損変異 / IL-1 / 1pr^<cg>マウス / IL-12p40 / CD4T細胞 / lpr^<cg>マウス / Lymphoproliferation / Vbeta8.2+ T cells / Mammary tumor virus / 1pr^<cg>遺伝子 / Vβ8.2T細胞 / マウス乳癌ウイルス / lymphadenopathy / artiritis / gromeluronephritis / congenic / autoimmunity / MRL background / mouse model / リンパ筋腫脹 / 血管炎 / コンジェニック / MRL背景 / マウスモデル / Homing / Complementation / Nephritis / Autoimmunity / Gld gene / Lpr^<cg> gene / 全身性リンパ節腫脹 / ホーミング / 腎炎 / 自己免疫 / Thymus / gld gene / Double-negative T cells / Mouse / ホ-ミング / 異常T細胞 / 胸腺 / CD4^ー8^ーT細胞 / 全身リンパ節腫脹 / hst / int-2 / 肺コロニー形成能 / コラゲナーゼ / MMTV遺伝子 / ヘテロジェナイティー / 染色体 / プロMMTV / 悪性化 / プロジェステロン受容体 / 活性化 / エストロジェン受容体 / 癌治療 / 肝癌 / gld / lpr / 抗Fas抗体 / Fas / アポトーシス / IV型コラケーナーゼ / ケラチン / hst遺伝子 / intー2遺伝子 / 転移能 / 乳癌の進展 … More
Except Principal Investigator
マウス乳癌 / 自己免疫 / アポトーシス / apoptosis / nitrosomethylurea / Retinitis pigmentosa / point mutation / p-53 / ND2001 / HCFU / LMFS / Collagen gel / Malignancy / cell interactions / Tumor-cell / Autonomous growth / Hormone-dependency / Heterogenity / Mouse mammary tumor / ヘテロジェナイテイ / コラーゲンゲル / 悪性度 / 細胞間相互作用 / 自律性増殖 / ホルモン依存性 / lpr^<cg> gene / 自己免疫病 / gp120 / HIV / Fas / 浸潤 / gld / lpr / Murine mammary tumor / Murine hepatoma / Apoptosis / FasL system / Cancer gene therapy / マウス肝癌 / Fas-FasLシステム / 癌遺伝子治療 / rosette / retinal dysplasia / pigment epithelial cell / retinal degeneration / photoreceptor cell / 色素上皮細胞 / 実験動物 / 視細胞 / ニトロソ尿素 / 色素性網膜変性症 / ロゼット / 網膜異形成 / 網膜変性 / Photoreceptor cell / Methallotionein / メタロチオネイン / HIV-I-Tgマウス / HTLV-I-Tgマウス / IL-12 / HTLV-I Tgマウス / HIV-Tgマウス / HTLV-L Tgマウス / IL-1レセプターアンタゴニスト / 関節リウマチ / HTLV-I / IL-6 / IFN-γ / IL-1β / IL-1α / ノックアウトマウス / トランスジェニックマウス / chemotherapy / Inhibition of metastasis / spontaneous liver metastasis / 化学療法 / 転移抑制 / 自然肝転移 / superantigen / mouse mammary tumor virus / MRL mouse / glomerlonehritis / autoimmune disease / VB8.2 / レトロウイルス / スーパー抗原 / マウス乳癌ウイルス / MRLマウス / lpr^<cg>遺伝子 / 糸球体腎炎 / Actinonin / 自律性進展 / アクチノーン / 肺転移能 / ヘテロジェナイティ / アクチノニン / ヘテロジェナィティ / idiotype network / autoimmunity / 抗gp120抗体 / 自己免疫マウス / イディオタイプネットワーク / 1pr^<cg>遺伝子 / 水晶体蛋白 / 白内障発症機構 / 白内障遺伝子 / 戻し交配 / 白内障モデル / NAKANOマウス / 遺伝性白内障マウス / 白内障 / MMTV-LTR / MMTVの定量法 / 乳癌前癌病変 / 乳癌抑制遺伝子 / MMTVゲノム / MMTV / 妊娠依存性乳癌 / ヒト乳癌抗原 / ヒト乳癌 / ラット乳癌 / スンクス乳癌 / 乳癌ウイルス / アポトーシスエンドヌクレアーゼ / トポイソメラーゼIIα / エンドトキシンLPS / myc関連遺伝子 / CED-3 family proteases / ICE / リンパ腫 / Pim-1キナーゼ / LPS / アポトーシス耐性 / カスパーゼ3様プロテアーゼ / アポトーシスシグナル / FasL / Bax / 制がん剤 / アデノウイルスE1A / Myc / ホーミング / DN細胞 / ヘテロ接合 / lprcg / 転移 / リンパ節腫脹 / lpr^<cg> Less
  • Research Projects

    (25 results)
  • Co-Researchers

    (40 People)
  •  Elucidation of the mechanism how Vβ T cells aggravate autoimmune diseases and establishment of T cell receptor (TCR)-targeted gene therapies of autoimmune diseasesPrincipal Investigator

    • Principal Investigator
      TAMURA Toshiki, 松澤 昭雄
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  A study for cancer gene therapy through Fas-mediated apoptosis

    • Principal Investigator
      TAKEDA Yasutaka
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Comparative pathological study of human retinitis pigmentosa and its animal models

    • Principal Investigator
      TSUBURA Airo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Kansai Medical University
  •  アポトーシス機構の解析とその発がん、制がん研究への応用

    • Principal Investigator
      口野 嘉幸
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  サイトカイン研究のための遺伝子改変マウスライブラリーの作製

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  Amelioration of lpr^<cg>-induced autoimmune diseases with Vbeta8.2-specific viral superantigen and its application to gene therapy in micePrincipal Investigator

    • Principal Investigator
      MATSUZAWA Akio
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  A study on tumor cell/cell interactions using mouse mammary tumor models

    • Principal Investigator
      TAKEDA Yasutaka
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  FAS-FASリガンド実験系を用いたアポトーシスによる癌治療の基礎的研究Principal Investigator

    • Principal Investigator
      松澤 昭雄
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Analysis and murine atoimmune disease utilizing a superantigen possessed by a retrovirus.

    • Principal Investigator
      KIMURA Mikio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      The University of Tokyo
  •  INVESTIGATION OF SPONTANEOUS LIVER METASTASIS MODEL OF BALB/c REIROPERITONEAL SARCOMA (LMFS) AND CLINICAL APPLICATION

    • Principal Investigator
      FUJII Yuzo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      The University of Tokyo
  •  Elucidation of properties and mechanism of development of autoimmune diseases in new congenic MRL/MpJ-lprcg/lprcg micePrincipal Investigator

    • Principal Investigator
      MATSUZAWA Akio
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  Study of Tumor Progression in vivo and in vitro using

    • Principal Investigator
      TAKEDA Yasutaka
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Role of anti-HIV-gp120 antibody in the lpr^<cg> and other autoimmune mice.

    • Principal Investigator
      KIMURA Mikio
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      The University of Tokyo
  •  lprcg、lpr及びgld異常リンパ球のリンパ節浸潤、転移機構の解明

    • Principal Investigator
      木村 幹男
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Studies on background genes aggravating lpr^<cg>-induced nephritis and complementation between lpr^<cg> and gld genesPrincipal Investigator

    • Principal Investigator
      MATSUZAWA Akio
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  lpr^<cg>,lpr及びgld異常リンパ球のリンパ節浸潤、転移機構の解明

    • Principal Investigator
      KIMURA Mikio
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Studies on the Mechanism of Induction of Autoimmune Disease by the Novel Lymphoproliferation gene, lpr^<cg>Principal Investigator

    • Principal Investigator
      MATSUZAWA Akio
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  ホルモン依存性乳癌の進展とヘテロジェナィティーPrincipal Investigator

    • Principal Investigator
      松沢 昭雄
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  ホルモン依存性乳癌の進展とヘテロジェナイティーPrincipal Investigator

    • Principal Investigator
      松沢 昭雄
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  ホルモン依存性乳癌の進展とヘテロジェナイティーPrincipal Investigator

    • Principal Investigator
      松沢 昭雄
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  白内障発生における遺伝子発現に及ぼす宿主因子の影響

    • Principal Investigator
      和田 栄子
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  ホルモン依存性乳癌の自律増殖能獲得機構の解明Principal Investigator

    • Principal Investigator
      松沢 昭雄
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  マウス乳癌ウイルス(MMTV)を中心とする各種動物の乳癌発生機構の比較解析

    • Principal Investigator
      星野 宗光
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya University
  •  Studies on the roles of collagens in cell proliferation and differentiation, tissue organization, and pathological changesPrincipal Investigator

    • Principal Investigator
      MATSUZAW akio
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  ホルモン依存性乳癌の自律増殖能獲得機構の解明Principal Investigator

    • Principal Investigator
      松沢 昭雄
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  • 1.  KIMURA Mikio (90114462)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  TSUBURA Airo (90098137)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  KATAGIRI Takuya (70126100)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  村上 昭 (50127148)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  YOSHIMOTO Takayuki (80202406)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TAKEDA Yasutaka (40163422)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  及川 勉 (40120141)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  SHIMIZU Motomu (10124463)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  WATANABE Tomomasa (10100174)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  NARIUCHI Hideo (10012741)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  TAMURA Toshiki (40291306)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  IKEDA Hidetoshi (60101119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  WAKABAYASHI Tomo (90092379)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  FUJII Yuzo (40143515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  YANAGIE Hironobu (30212278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MORI Shigero (30010424)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  SAYAMA Kazutoshi (30260582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MIKI Hirohiko (30077771)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SENZAKI Hideto (10206659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKANO Hideki (30266928)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TANAKA Shin (70134624)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  口野 嘉幸 (60124418)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  中島 琢磨 (90256678)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  田沼 靖一 (10142449)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  三浦 正幸 (50202338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  藤田 直也 (20280951)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  堂福 隆一 (50099975)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  岩口 孝雄 (40085634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  星野 宗光 (10073107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  土田 信夫 (60089951)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  今井 俊介 (10075038)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  大野 典也 (60147288)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  田中 春高 (10027310)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  和田 栄子 (70114725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  保田 立二 (30092357)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  岩倉 洋一郎 (10089120)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  須藤 カツ子 (50126091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  浅野 雅秀 (50251450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  田川 陽一 (70262079)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  SAEGUSA Yoshiyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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